CN105477625B - A kind of absorption dust discharge Chinese herbal and crude drugs preparationses and preparation method thereof - Google Patents
A kind of absorption dust discharge Chinese herbal and crude drugs preparationses and preparation method thereof Download PDFInfo
- Publication number
- CN105477625B CN105477625B CN201510953666.3A CN201510953666A CN105477625B CN 105477625 B CN105477625 B CN 105477625B CN 201510953666 A CN201510953666 A CN 201510953666A CN 105477625 B CN105477625 B CN 105477625B
- Authority
- CN
- China
- Prior art keywords
- chinese herbal
- dust discharge
- crude drugs
- radix
- dust
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/723—Xanthans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/729—Agar; Agarose; Agaropectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/732—Pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/734—Alginic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Insects & Arthropods (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Otolaryngology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Husbandry (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to technical field of Chinese medicine, specifically disclose a kind of absorption dust discharge Chinese herbal and crude drugs preparationses and preparation method thereof.This absorption dust discharge Chinese herbal and crude drugs preparations is made up of following raw material：Ganoderma, Poria, Radix Asparagi, the Radix Astragali, Herba Dendrobii, Bulbus Fritillariae Cirrhosae, Folium Eriobotryae, Radix Codonopsis, Pericarpium Citri Reticulatae, Radix Isatidis, Fructus Schisandrae Chinensis, Semen Trichosanthis, Flos Lonicerae, Fructus Alpiniae Oxyphyllae, Semen Armeniacae Amarum, Rhizoma Zingiberis Recenss, Radix Glycyrrhizae, Fructus Momordicae, Flos lupuli (Flos Humuli Lupuli), mature vinegar, Mentholum, Sal, propolis, xanthan gum, guar gum, gelatin, sodium alginate, agar, glucosan, pectin, Mel, maltose, syrup, water.The colloid absorption pulmonary dust that each raw material synergism dissolves dust, formed, forms sputum, excretes；Meanwhile, play the effects such as antiinflammatory, antibacterial and antiviral, prevent and treat lung tissue inflammation further, promote dust discharge, it is to avoid the infection to lung tissue for the respiratory pathogen.In addition, said preparation storage and transport are convenient, using easy and simple to handle.
Description
Technical field
The present invention relates to technical field of Chinese medicine is and in particular to a kind of adsorb dust discharge Chinese herbal and crude drugs preparationses and preparation method thereof.
Background technology
Pneumoconiosis are gradually to develop after human lung tissue sucks dust to form.This dust one side is derived from commercial production
During, such as mine operation etc., people can suffer from pneumoconiosis because of the long-term various dust sucking in working environment；The opposing party
Face comes from atmospheric pollution, such as lives in the environment that haze weather occurs, can gradually suffer from slight pneumoconiosis.Pneumoconiosis can
To lead to patient lungs' pathological changes, easily cause pulmonary tuberculosis, once suffering from above-mentioned disease, the lighter reduces work capacity, weight simultaneously
Person causes systemic organs to die of exhaustion to die, and the disease directly resulting in except dust, the extraneous pathogen such as lung that dust carries
The pathogenetic bacterias such as tubercule bacillus, influenza virus, streptococcus pneumoniae and virus all can lead to the pulmonary infection disease of human body.Therefore,
More and more frequent, increasingly severe, the pneumoconiosis also more and more lifes that govern people occurring with haze weather in recent years
Live, cause the attention of people.It is to fill lung treatment currently for the maximally effective Therapeutic Method of pneumoconiosis, but fill lung treatment and patient is caused
Injury big, costly, weak curative effect it is difficult to promote, and for the pneumoconiosis patients with other symptoms such as pulmonary tuberculosis, nor
Treated using filling lung.Except filling lung treatment, the such as mode of the Drug therapy such as bronchial dilation agent and antiinflammatory, it is only capable of to the state of an illness
Play mitigation, dust discharge effect notable it is impossible to fundamentally remove the pathogenic dust of pulmonary, such as medicated cigarette flue dust or
The pneumoconiosis that atmospheric aerosol leads to, lacking effective Therapeutic Method at present will be direct for the toxic granular such as medicated cigarette flue dust or atmospheric aerosol
Discharge.Therefore, in the urgent need to researching and developing a kind of pharmaceutical preparation with significant dust suction dust discharge effect.
Pharmaceutical preparation with Chinese herbal medicine as raw material while preventing and treating disease, due to having low toxic and side effects
Increasingly pursued by people, and be developed research and be applied in various prevention and treatment of diseases, hence with Chinese herbal medicine
The disease that the materials such as prevention and treatment dust cause is increasingly becoming focus.
Content of the invention
In order to overcome the defect of prior art, it is an object of the invention to provide a kind of absorption dust discharge Chinese herbal and crude drugs preparationses, this suction
Attached dust discharge Chinese herbal and crude drugs preparationses not only have significantly molten dirt, dust suction and dust discharge effect, also have the effect eliminating pneumoconiosis inflammation；Enter
One step, moreover it is possible to kill and suppression pulmonary pathogen, prevents and treats respiratory tract infection.
Meanwhile, the present invention also resides in the preparation method providing a kind of absorption dust discharge Chinese herbal and crude drugs preparationses.
In order to realize object above, the technical solution adopted in the present invention is：
A kind of absorption dust discharge Chinese herbal and crude drugs preparationses, are made up of the raw material of following weight percentage：Ganoderma 0.1～1%, Poria
0.1～1%, Radix Asparagi 0.1～1%, the Radix Astragali 0.1～1%, Herba Dendrobii 0.1～1%, Bulbus Fritillariae Cirrhosae 0.1～1%, Folium Eriobotryae 0.1～
1%th, Radix Codonopsis 0.1～1%, Pericarpium Citri Reticulatae 0.1～1%, Radix Isatidis 0.1～1%, Fructus Schisandrae Chinensis 0.1～1%, Semen Trichosanthis 0.1～1%, mountain
Flos Lonicerae 0.1～1%, Fructus Alpiniae Oxyphyllae 0.1～1%, Semen Armeniacae Amarum 0.1～1%, Rhizoma Zingiberis Recenss 0.1～1%, Radix Glycyrrhizae 0.1～1%, Fructus Momordicae 0.1
～1%, Flos lupuli (Flos Humuli Lupuli) 0.1～1%, mature vinegar 0.1～1%, Mentholum 0.1～1%, Sal 0.1～1%, propolis 0.01～
0.1%th, xanthan gum 0.01～0.1%, guar gum 0.01～0.1%, gelatin 0.01～0.1%, sodium alginate 0.01～
0.1%th, agar 0.01～0.1%, glucosan 0.01～0.1%, pectin 0.01～0.1%, Mel 1～20%, maltose 1～
10%th, syrup 30-50%, balance of water.
Preferably, above-mentioned absorption dust discharge Chinese herbal and crude drugs preparationses, are made up of the raw material of following weight percentage：Ganoderma 0.1～
0.5%th, Poria 0.1～0.5%, Radix Asparagi 0.1～0.5%, the Radix Astragali 0.1～0.5%, Herba Dendrobii 0.1～0.5%, Bulbus Fritillariae Cirrhosae 0.1～
0.5%th, Folium Eriobotryae 0.1～0.5%, Radix Codonopsis 0.1～0.5%, Pericarpium Citri Reticulatae 0.1～0.5%, Radix Isatidis 0.1～0.5%, Fructus Schisandrae Chinensis
0.1～0.5%, Semen Trichosanthis 0.1～0.5%, Flos Lonicerae 0.1～0.5%, Fructus Alpiniae Oxyphyllae 0.1～0.5%, Semen Armeniacae Amarum 0.1～0.5%,
Rhizoma Zingiberis Recenss 0.1～0.5%, Radix Glycyrrhizae 0.1～0.5%, Fructus Momordicae 0.1～0.5%, Flos lupuli (Flos Humuli Lupuli) 0.1～0.5%, mature vinegar 0.1～
0.5%th, Mentholum 0.1～0.5%, Sal 0.1～0.5%, propolis 0.01～0.05%, xanthan gum 0.01～0.05%, melon
That locust beam gum 0.01～0.05%, gelatin 0.01～0.05%, sodium alginate 0.01～0.05%, agar 0.01～0.05%, Portugal
Polysaccharide 0.01～0.05%, pectin 0.01～0.05%, Mel 1～10%, maltose 1～5%, syrup 30-50%, balance of
Water.
The abbreviated functional description of each raw material：
Ganoderma：Invigorating QI and tranquilization, relieving cough and asthma.
The Radix Astragali：Invigorating QI to consolidate the body surface resistance, diuresis, expelling pus and toxin by strengthening QI, granulation promoting, promote lung tissue dust discharge and the regeneration promoting lung tissue.
Herba Dendrobii：Lung benefiting promotes the production of body fluid, nourishing YIN and clearing away heat.
Bulbus Fritillariae Cirrhosae：Clearing heat and moistening lung, preventing phlegm from forming and stopping coughing.For lung-heat type cough, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood.
Folium Eriobotryae：Clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.For cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastric heat vomiting, dysphoria and thirsty.
Radix Codonopsis：Nourishing YIN and moistening the lung, reinforcing stomach reg fluid.For yin chronic cough, consumptive disease is coughed expectorant blood, and cough caused by dryness expectorant is few, deficiency-heat sore throat, Tianjin wound
Yearningly.
Poria：Sweet in the mouth, light, mild-natured, energy eliminating dampness and diuresises, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.Cure mainly dysuria, oedema turgor,
Phlegm retention cough with dyspnea, vomiting, spleen eating less, have loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine.
Pericarpium Citri Reticulatae：Preventing phlegm from forming and stopping coughing.Cure mainly cough due to wind and cold, chronic cough, tracheitiies, asthma.
Radix Isatidis：Lung qi dispersing, sore-throat relieving, eliminating the phlegm, evacuation of pus.For cough with copious phlegm, smooth, pharyngalgia, hoarseness, lung carbuncle pyemesis uncomfortable in chest,
Skin infection pus become to burst.
Radix Asparagi：Drying dampness to eliminate phlegm, for abundant expectoration cough and asthma, phlegm retention anti-dazzle nervous, dizziness due to wind-phlegm, phlegm and headache.
Fructus Schisandrae Chinensis：Astringe the lung, nourishing kidney, promote the production of body fluid, receive antiperspirant, arresting seminal emission.It is thin to control that the deficiency of the lung is breathed with cough, xerostomia makees thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain
Thin, emission, protracted dysentery and diarrhea.
Semen Trichosanthis：Moistening the lung and resolving phlegm, laxation relieving constipation, phlegm-heat cough, deficiency of the lung cough caused by dryness, dry constipation, ulcerative carbuncle pyogenic infections.
Flos Lonicerae：Heat-clearing and toxic substances removing, dispelling wind and heat pathogens.Treat skin ulcer, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, temperature for carbuncle
Heat morbidity.
Fructus Alpiniae Oxyphyllae：Control palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, carbuncle sore swells.Cure mainly tranquilize the mind and promote the intelligence, resolving depression.
Semen Armeniacae Amarum：Cough-relieving is coughed, expectorant lung moistening, intestine moistening stomach, the flour that disappears amass, the therapeutic method to keep the adverse QI flowing downwards.
Rhizoma Zingiberis Recenss：CORTEX ZINGIBERIS RHIZOMAE is pungent cool, controls skin edema, the row severe edema due to hypofunction of the spleen；Rhizoma Zingiberis Recens juice pungent-warm, pungent scattered cold syndrome of the stomach strength is strong, is used for
Vomiting；Rhizoma Zingiberiss pungent-warm, warming middle-JIAO instigates cold, Back to Yang Tongmai, and warming the spleen is trembled with fear, and strength is big, and Rhizoma Zingiberis Preparatum acrid in the mouth is bitter, does not walk table in walking, lower Jiao's of temperature
Cold；Carbonized Rhizoma Zingiberis (processed) is warm in nature, and relatively homoiothermy divides trembling with fear；The bitter temperature of Roast Rhizoma Zingiberis Recens, relatively warming intestines and stomach is cold.The pungent and scattered temperature of Rhizoma Zingiberis Recenss, Energy benefit taste, it is apt to temperature
Middle stopping nausea and vomiting by lowering the adverse flow of QI, dehumidify the painful abdominal mass that disappears, and eliminating phlegm and stopping cough, with stopping nausea and vomiting by lowering the adverse flow of QI as length.
Radix Glycyrrhizae：Licoflavone, Radix Glycyrrhizae extractum and enoxolone all have obvious antitussive effect；Phlegm-dispelling functions are also more significant.
Fructus Momordicae：Fructus Momordicae sweet in the mouth is cool in nature, return lung, large intestine channel, has functions that nourishing the lung to arrest cough, promoting the production of body fluid to quench thirst it is adaptable to lung
Heat or xeropulmonary cough, pertussis and summer-heat fluid deficiency and thirsty etc., in addition with effect of loosening bowel to relieve constipation.
Flos lupuli (Flos Humuli Lupuli)：There is antiinflammatory, effect that sterilization, antibacterial, invigorating the stomach and promoting digestion, diuresis are calmed the nerves.Control dyspepsia, abdominal distention, float
Swollen, cystitis, pulmonary tuberculosis, insomnia.Cure mainly leprosy, pulmonary tuberculosis, pneumosilicosis, tuberculous lymphadenitiss, dysentery.
Mature vinegar：Containing organic acid such as acetic acid bacterias, many mineral dust can be dissolved, bulk dust is degraded into fritter dust
And finely ground particle substance, beneficial to the dissolving of dust, absorption and discharge.
Mentholum：The Cold receptor of human body skin or mucosa can optionally be stimulated, produce sense of cold reflection and creeping chill, draw
Play skin mucosa vasoconstriction；In addition also contraction can be caused to the blood vessel of deep tissue, and produce therapeutical effect.
Sal：Maintain the ionic equilibrium of lung tissue cell, moistening lung tissue, make up lung tissue cell secretion sodium chloride liquid
Deficiency；Reduce the viscosity of colloid or sputum, promote the dust discharge of lung tissue.
Propolis：Form colloid, adsorption of dust forms sputum, promote the discharge of dust, there is antibacterial, antiinflammatory work simultaneously
With.
Xanthan gum：Form colloid, adsorption of dust forms sputum, promote the discharge of dust, xanthan gum is to solution soda acid simultaneously
Degree change is insensitive, improves the stability of colloid；
Guar gum：Form colloid, adsorption of dust forms sputum, promote the discharge of dust, the amino of formation of simultaneously degrading
The compositions such as acid are nutritious to cell and protective effect.
Gelatin：Form colloid, adsorption of dust forms sputum, promote the discharge of dust, aminoacid of formation etc. of simultaneously degrading
Composition is nutritious to cell and protective effect.
Sodium alginate：It is dissolved in Aquatic product rubber body, adsorption of dust forms sputum, promote the discharge of dust.
Agar：It is prepared from by agarose and agar pectin, have and be thermally formed colloid, adsorption of dust, promote to form expectorant
Effect of liquid；The colloid hydrophilic being formed is strong, is easily separated from lung cilium, reduces the viscosity forming sputum, is conducive to sputum to discharge.
Glucosan：Form colloid, adsorption of dust, promote sputum to be formed, meanwhile, promote lung tissue and the immunocompetence of cell
Raising, suppress the infection to lung tissue for the pathogen, there is the dual function of antiinflammatory and dust discharge.
Pectin：Form colloid, adsorption of dust, promote sputum to be formed.
Mel：Containing colloid composition, adsorption of dust forms sputum, promotes the discharge of dust, has antibacterial, antiinflammatory simultaneously
Effect.
Maltose：As sweeting agent, increase sweet taste, contain micro colloid, adsorption of dust simultaneously, promote dust to form sputum
Excrete.
Syrup：As sweeting agent, keep sweet taste, concurrently facilitate auxiliary and make pulpous state together with other raw materials.
Present invention absorption dust discharge Chinese herbal and crude drugs preparationses have the advantages that：
1st, each raw material synergism in the composition of raw materials of present invention absorption dust discharge Chinese herbal and crude drugs preparationses, has certain dissolving powder
Effect of dirt, specially：First, the organic acid such as the acetic acid that contains in mature vinegar, citric acid can dissolve and degrade mineral dust；
Secondly, Ganoderma, the Radix Astragali, Herba Dendrobii, Mel, syrup, Bulbus Fritillariae Cirrhosae, Folium Eriobotryae, Radix Codonopsis, Poria, Pericarpium Citri Reticulatae, Radix Isatidis, Radix Asparagi, the five tastes
Son, Semen Trichosanthis, Flos Lonicerae, Fructus Alpiniae Oxyphyllae, Semen Armeniacae Amarum, Rhizoma Zingiberis Recenss, Radix Glycyrrhizae, Fructus Momordicae, contain a certain amount of Determination of Organic Acids in Flos lupuli (Flos Humuli Lupuli),
These organic acid can to a certain extent to some resolvabilitys the Dust such as resolvability metal such as calcic, ferrum, magnesium
Dust has certain dissolving and degradation capability, forms less particulate matter, is conducive to the further absorption of dust and discharges；
Meanwhile, the microorganism of lung tissue and lung tissue utilizes the degraded of the sugar such as Mel, syrup, maltose to produce some organic acid, right
Lung tissue dust plays deliquescent effect；
2nd, the present invention adsorb dust discharge Chinese herbal and crude drugs preparationses composition of raw materials in each raw material synergism, have very strong dust suction and
Dust discharge effect, specially：Propolis, xanthan gum, guar gum, gelatin, sodium alginate, agar, glucosan, pectin, Mel are worked in coordination with
Effect forms complicated, stable, multi-functional colloid, this colloid can dust in active adsorption lung tissue, form sputum, row
Go out external；Chinese medicine ingredients Ganoderma in composition of raw materials, the Radix Astragali, Herba Dendrobii, Bulbus Fritillariae Cirrhosae, Folium Eriobotryae, Radix Codonopsis, Poria, Pericarpium Citri Reticulatae, Baphicacanthus cusia
Root, Radix Asparagi, Fructus Schisandrae Chinensis, Semen Trichosanthis, Flos Lonicerae, Fructus Alpiniae Oxyphyllae, Semen Armeniacae Amarum, Rhizoma Zingiberis Recenss, Radix Glycyrrhizae, Fructus Momordicae, Flos lupuli (Flos Humuli Lupuli) contain a certain amount of
Polysaccharide and pectic substance, have the characteristic of colloid, it may have the property of certain adsorption of dust and effect.Above-mentioned raw material of Chinese medicine
In polysaccharide and pectic substance, cooperatively form colloid with the polysaccharide such as xanthan gum, guar gum, Mel and colloidal substance, absorption
Dust in lung tissue, promotes dust to form sputum and excretes, it is to avoid dust to the stimulation further of lung tissue and injury, from
And play the effect of effective protection lung tissue.
These compositions of propolis, xanthan gum, guar gum, gelatin, sodium alginate, agar, glucosan, pectin, Mel contain
The material of macromole, can by being cross-linked to form colloid although these colloid molecules are nontoxic, but this long-chain colloid molecules pair
Human body body still can produce certain direct stimulation or immunostimulation, in order to avoid colloid composition single in a large number stimulates
The lung tissue of human body, the present invention adopts this complicated multi-component colloid, thus as avoiding single colloid molecules excessive as possible
Stimulate lung tissue；Again because of the such as Chinese medicine ingredients such as Radix Glycyrrhizae, Flos lupuli (Flos Humuli Lupuli), Radix Isatidis of the Chinese herbal medicine containing antiinflammatory in Chinese herbal medicine, this
Prevent the stimulation to lung tissue for the colloid macromolecules material to a certain extent；Secondly, propolis, xanthan gum, guar gum, bright
Glue, sodium alginate, agar, glucosan, pectin, the combination of Mel, had both contained ionic colloid, also contained nonionic colloid,
This composite colloid is more stablized it is not easy to lead to precipitation or rotten because of the factor such as pH value, temperature change.
Generally, the lung tissue such as lung cilium can secret out of normal saline and various albumen mucus forms colloid, inhales
Attached dust, formation sputum, form the first line of defence that prevention dust stimulates.If the Dust Capacity that human body sucks is than relatively low situation
Under, Human Lung cilium can secret out of enough cilium surface colloids, adsorption of dust, form the materials such as sputum and excrete.
Because this secretion, absorption and dust discharging function are powerful, generally, what human body will not be subject to external dust to suck and bring hinders
Evil.But, if encountering dry, arctic weather, the lung mucous secretion of human body is not enough, or external dust enters in a large number and exhausts
The lung cilium colloid mucus of human body, at this time human body tend not to be discharged into a large amount of dust of human body, and these are not discharged
Dust can gradually accumulate and stimulate further and injure the lung tissues such as lung ciliated epithelial cell or macrophage.Due to human body
The weakening of lung tissue dust discharging function, the Dust Capacity that human body is discharged gradually decreases；Meanwhile, the Dust Capacity that human lung tissue accumulates is gradually
Increase, these unnecessary dust gradually can form other healthy lung tissues of invasion and attack of landslide formula, thus gradually destroying whole human body
Lung tissue.
Present invention absorption dust discharge Chinese herbal and crude drugs preparationses contain various colloids and Sal, and these colloid solution fully simulate people
The colloid composition of body lung cilium rete malpighii and structure, when human lung tissue lacks lung cilium colloid layer, by supplementing this
Planting colloid, repairing and strengthen the absorption of lung tissue, the mechanism forming sputum and discharging sputum, thus avoiding dust to lung group
The stimulation further knitted and injury, and then lung tissue is played with protection and the effect of prevention dust inhalation hazard.Under normal circumstances,
Lung tissue cilium is difficult to discharge to very tiny granule, and the colloid that the absorption dust discharge Chinese herbal and crude drugs preparationses of the present invention are formed adsorbs powder
Dirt forms oarse-grained sputum composition, thus promoting the discharge of little particle dust material；
3rd, each raw material synergism in the formula of present invention absorption dust discharge Chinese herbal and crude drugs preparationses, has very strong anti-inflammatory effect,
It is specially：In the case of excessive dust stimulates, lung tissue cannot remove these dust, and these dust not only injure lung tissue,
Stimulate the death of lung tissue cell and come off, and produce serious inflammation, the dust discharging function of suppression lung tissue, further add
The weight injury to lung tissue for the dust.The present invention absorption dust discharge Chinese herbal and crude drugs preparationses in Ganoderma, the Radix Astragali, Herba Dendrobii, Bulbus Fritillariae Cirrhosae, Folium Eriobotryae,
Radix Codonopsis, Poria, Pericarpium Citri Reticulatae, Radix Isatidis, Radix Asparagi, Fructus Schisandrae Chinensis, Semen Trichosanthis, Flos Lonicerae, Fructus Alpiniae Oxyphyllae, Semen Armeniacae Amarum, Rhizoma Zingiberis Recenss, Radix Glycyrrhizae, Fructus Momordicae,
Flos lupuli (Flos Humuli Lupuli) can work in coordination with the significant anti-inflammatory effect of generation；Meanwhile, the propolis in present invention absorption dust discharge Chinese herbal and crude drugs preparationses, glucosan
There is certain antiinflammation.Pneumonia can be eliminated after each raw material synergism in absorption dust discharge Chinese herbal and crude drugs preparationses, alleviate lung
The symptom in portion, promotes the recovery of pulmonary function, promotes the dust discharge of lung tissue itself；
4th, the present invention adsorbs each raw material synergism in the formula of dust discharge Chinese herbal and crude drugs preparationses, has very strong sterilization and antibacterial
And effect of antiviral, specially：Ganoderma, Poria, Radix Asparagi, the Radix Astragali, Herba Dendrobii, Pericarpium Citri Reticulatae, Radix Isatidis, Fructus Schisandrae Chinensis, Semen Trichosanthis, mountain
Flos Lonicerae, Fructus Alpiniae Oxyphyllae, Semen Armeniacae Amarum, Rhizoma Zingiberis Recenss, Radix Glycyrrhizae, Fructus Momordicae, Flos lupuli (Flos Humuli Lupuli), propolis, glucosan all have certain sterilization, antibacterial and
Effect of antiviral, can assist prevention and treatment to suffer from phthisical Pneumoconiosis Patients, prevention Pneumoconiosis Patients infection pulmonary tuberculosis
Deng respiratory pathogen.
The present invention adsorbs dust discharge Chinese herbal and crude drugs preparationses, the colloid absorption pulmonary dust that each raw material cooperatively forms, and forms sputum, row
Go out external, it is to avoid the harm to pulmonary for the dust；Meanwhile, each raw material in absorption dust discharge Chinese herbal and crude drugs preparationses is worked in coordination with and is played antiinflammatory, suppression
Effect of bacterium and antiviral etc., treats lung tissue inflammation further, promotes dust discharge, and avoids respiratory pathogen to pulmonary's group
The infection knitted.
The preparation method of above-mentioned absorption dust discharge Chinese herbal and crude drugs preparationses, including following operating procedure：
1) take each raw material mix homogeneously, heating infusion is obtained serosity；
2) by step 1) serosity prepared filters, sterilizing, obtains final product described absorption dust discharge Chinese herbal and crude drugs preparationses.
Step 1) described in heating temperature be 80～100 DEG C.
Step 1) described in heating time be 1～6 hour.
Step 2) in also include by sterilizing after serosity be contained in spray bottle.
The present invention adsorbs the preparation method of dust discharge Chinese herbal and crude drugs preparationses, and present invention absorption dust discharge Chinese herbal and crude drugs preparationses are prepared pulping
Shape dosage form, the absorption dust discharge Chinese herbal and crude drugs preparationses of pulpous state are contained in spray bottle, during use are sprayed spray bottle spout be aligned human oral cavity
Mist, will adsorb the atomization of dust discharge Chinese herbal and crude drugs preparationses by spray bottle, and human body passes through actively breathing and will be atomized absorption dust discharge Chinese herbal and crude drugs preparationses
Suck pulmonary, produce therapeutical effect, easy to use.The viscosity of the pulpous state Chinese herbal and crude drugs preparationses of present invention preparation herein is moderate, energy
Enough sprayed by spray bottle, form spraying.
The present invention adsorbs the preparation method of dust discharge Chinese herbal and crude drugs preparationses, easy and simple to handle it is easy to control, the pulpous state preparation of preparation is easy
In storage and transport, easy to use, suitable large-scale promotion application.
Specific embodiment
Below by specific embodiment, technical scheme is described in detail.
Embodiment 1
The present embodiment adsorbs dust discharge Chinese herbal and crude drugs preparationses, is made up of the raw material of following weight percentage：Ganoderma 0.1%, Fu
Siberian cocklebur 0.1%, Radix Asparagi 0.1%, the Radix Astragali 0.1%, Herba Dendrobii 0.1%, Bulbus Fritillariae Cirrhosae 0.1%, Folium Eriobotryae 0.1%, Radix Codonopsis 0.1%, Pericarpium Citri Reticulatae
0.1%th, Radix Isatidis 0.1%, Fructus Schisandrae Chinensis 0.1%, Semen Trichosanthis 0.1%, Flos Lonicerae 0.1%, Fructus Alpiniae Oxyphyllae 0.1%, Semen Armeniacae Amarum 0.1%,
Rhizoma Zingiberis Recenss 0.1%, Radix Glycyrrhizae 0.1%, Fructus Momordicae 0.1%, Flos lupuli (Flos Humuli Lupuli) 0.1%, mature vinegar 0.1%, Mentholum 0.1%, Sal 0.1%,
Propolis 0.01%, xanthan gum 0.01%, guar gum 0.01%, gelatin 0.01%, sodium alginate 0.01%, agar 0.01%,
Glucosan 0.01%, pectin 0.01%, Mel 1%, maltose 1%, syrup 50%, balance of water.
The present embodiment adsorb dust discharge Chinese herbal and crude drugs preparationses preparation method be：Take each raw material by proportioning, be uniformly mixed, plus
Heat is to 80 DEG C of infusions 6 hours, prepared serosity；Serosity filters, and is dispensed in spray bottle after sterilizing, obtains final product described absorption dust discharge medium-height grass
Medicine preparation.
The present embodiment absorption dust discharge Chinese herbal and crude drugs preparationses, when using, are sprayed to human oral cavity with spray bottle, human body passes through
Actively the absorption dust discharge Chinese herbal and crude drugs preparationses after atomization are sucked pulmonary by breathing, play curative effect of medication, reach treatment and prevention pneumoconiosis
The purpose of disease.
Embodiment 2
The present embodiment adsorbs dust discharge Chinese herbal and crude drugs preparationses, is made up of the raw material of following weight percentage：Ganoderma 0.5%, Fu
Siberian cocklebur 0.5%, Radix Asparagi 0.5%, the Radix Astragali 0.5%, Herba Dendrobii 0.5%, Bulbus Fritillariae Cirrhosae 0.5%, Folium Eriobotryae 0.5%, Radix Codonopsis 0.5%, Pericarpium Citri Reticulatae
0.5%th, Radix Isatidis 0.5%, Fructus Schisandrae Chinensis 0.5%, Semen Trichosanthis 0.5%, Flos Lonicerae 0.5%, Fructus Alpiniae Oxyphyllae 0.5%, Semen Armeniacae Amarum 0.5%,
Rhizoma Zingiberis Recenss 0.5%, Radix Glycyrrhizae 0.5%, Fructus Momordicae 0.5%, Flos lupuli (Flos Humuli Lupuli) 0.5%, mature vinegar 0.5%, Mentholum 0.5%, Sal 0.5%,
Propolis 0.05%, xanthan gum 0.05%, guar gum 0.05%, gelatin 0.05%, sodium alginate 0.05%, agar 0.05%,
Glucosan 0.05%, pectin 0.05%, Mel 10%, maltose 5%, syrup 40%, balance of water.
The present embodiment adsorbs dust discharge Chinese herbal and crude drugs preparationses, and preparation method is as follows：Take each raw material in proportion, be uniformly mixed,
It is heated to 90 DEG C of infusions 3 hours, prepared serosity；It is dispensed in spray bottle after serosity filtration, sterilizing, obtain final product in described absorption dust discharge
Herbal medicinal product.
The present embodiment absorption dust discharge Chinese herbal and crude drugs preparationses, when using, are sprayed to human oral cavity with spray bottle, human body passes through
Actively the absorption dust discharge Chinese herbal and crude drugs preparationses after atomization are sucked pulmonary by breathing, play curative effect of medication, reach treatment and prevention pneumoconiosis
The purpose of disease.
Embodiment 3
The present embodiment adsorbs dust discharge Chinese herbal and crude drugs preparationses, is made up of the raw material of following weight percentage：Ganoderma 1%, Poria
1%th, Radix Asparagi 1%, the Radix Astragali 1%, Herba Dendrobii 1%, Bulbus Fritillariae Cirrhosae 1%, Folium Eriobotryae 1%, Radix Codonopsis 1%, Pericarpium Citri Reticulatae 1%, Radix Isatidis 1%, five
Taste 1%, Semen Trichosanthis 1%, Flos Lonicerae 1%, Fructus Alpiniae Oxyphyllae 1%, Semen Armeniacae Amarum 1%, Rhizoma Zingiberis Recenss 1%, Radix Glycyrrhizae 1%, Fructus Momordicae 1%, medicated beer
Spend 1%, mature vinegar 1%, Mentholum 1%, Sal 1%, propolis 0.1%, xanthan gum 0.1%, guar gum 0.1%, gelatin
0.1%th, sodium alginate 0.1%, agar 0.1%, glucosan 0.1%, pectin 0.1%, Mel 20%, maltose 10%, syrup
30%th, balance of water.
The present embodiment adsorbs dust discharge Chinese herbal and crude drugs preparationses, and preparation method is：1) take each raw material by weight, stirring mixing is all
Even, it is heated to 100 DEG C of infusions 1 hour, prepared serosity；Serosity filters, and is dispensed in spray bottle after sterilizing, obtains final product described absorption row
Dirt Chinese herbal and crude drugs preparationses.
The present embodiment absorption dust discharge Chinese herbal and crude drugs preparationses, when using, are sprayed to human oral cavity with spray bottle, human body passes through
Actively the absorption dust discharge Chinese herbal and crude drugs preparationses after atomization are sucked pulmonary by breathing, play curative effect of medication, reach treatment and prevention pneumoconiosis
The purpose of disease.
Comparative example 1
This comparative example Chinese medicine preparation, is made up of the raw material of following weight percentage：Ganoderma 0.1%, Poria 0.1%, sky
Winter 0.1%, the Radix Astragali 0.1%, Herba Dendrobii 0.1%, Bulbus Fritillariae Cirrhosae 0.1%, Folium Eriobotryae 0.1%, Radix Codonopsis 0.1%, Pericarpium Citri Reticulatae 0.1%, Baphicacanthus cusia
Root 0.1%, Fructus Schisandrae Chinensis 0.1%, Semen Trichosanthis 0.1%, Flos Lonicerae 0.1%, Fructus Alpiniae Oxyphyllae 0.1%, Semen Armeniacae Amarum 0.1%, Rhizoma Zingiberis Recenss 0.1%,
Radix Glycyrrhizae 0.1%, Fructus Momordicae 0.1%, Flos lupuli (Flos Humuli Lupuli) 0.1%, mature vinegar 0.1%, Mentholum 0.1%, syrup 50%, balance of water.
The preparation method of this comparative example Chinese herbal and crude drugs preparations is with embodiment 1.
Comparative example 2
This comparative example colloid agent, is made up of the raw material of following weight percentage：Propolis 0.01%, xanthan gum
0.01%th, guar gum 0.01%, gelatin 0.01%, sodium alginate 0.01%, agar 0.01%, glucosan 0.01%, pectin
0.01%th, Mel 1%, maltose 1%, syrup 50%, balance of water.
The preparation method of this comparative example pharmaceutical preparation is with embodiment 1.
Comparative example 3
This comparative example Chinese herbal microecological preparation is formed by Chinese medicine extraction liquid inoculation red tea funguss mother liquor for fermentation, and wherein Chinese medicine carries
Liquid is taken to be made up of the raw material of following weight percentage：Folium Camelliae sinensis 1%, Radix Glycyrrhizae 1%, Flos Chrysanthemi 1%, Fructus Momordicae 1%, Semen Sterculiae Lychnophorae 1%,
Water 95%；Black tea mother bacterial liquid is prepared from by following methods：By 1L distilled water put in pot boiled after, sequentially add sucrose 5%,
Folium Camelliae sinensis 5%, ammonium sulfate 0.1%, potassium dihydrogen phosphate 0.1%, after waiting water boiled again, filter off Folium Camelliae sinensis with gauze, are cooled to 30 DEG C
Afterwards, red tea funguss, quiescent culture 10 days under the conditions of 30 DEG C, prepared black tea mother bacterial liquid are accessed；The inoculum concentration of wherein black tea mother bacterial liquid is
20%；The preparation method of wherein Chinese medicine extraction liquid is：Folium Camelliae sinensis, Radix Glycyrrhizae, Flos Chrysanthemi, Fructus Momordicae, Semen Sterculiae Lychnophorae is taken to be added to the water, mixing is all
Even, after boiling 25min, filter, prepared Chinese medicine extraction liquid；Wherein Chinese medicine extraction liquid inoculate black tea mother bacterial liquid fermentation process be：
Inoculate black tea mother bacterial liquid in Chinese medicine extraction liquid, quiescent culture 6 months, is dispensed in spray bottle after filtration under 30 DEG C of environment.
Clinical effect trial compares the pharmaceutical preparation of comparative example 1～3 preparation and the absorption dust discharge Chinese herbal medicine of embodiment 1 preparation
The absorption dust discharge effect of preparation, is specifically evaluated with the therapeutic effect to pneumoconiosis.
Test method：With I, II, III phase Pneumoconiosis Patients totally 420, at 30～50 years old age, wherein suffer from the pneumoconiosis I phase
Front 60, the I phase 180, the II phase 120, the III phase 60, above-mentioned 420 patients are equally divided into four according to pneumoconiosis degree
Group, one group 105；The wherein first group absorption dust discharge Chinese herbal and crude drugs preparationses taking embodiment 1 preparation, take comparative example 1 for second group
The Chinese medicine preparation of preparation, the 3rd group of colloid agent taking comparative example 2 preparation, the 4th group of Traditional Chinese drug microecology taking comparative example 3
Preparation；The usage and dosage of first to fourth group of drug administration：Mouthspray amount is 5-10ml every time, 1-2 times/day of spraying treatment,
3-5 minute every time, continuous 2 months.
Criterion of therapeutical effect：
It is clearly better：Clinical symptoms significantly improve, meanwhile, X piece significant difference before and after treatment；
Take a turn for the better：Clinical symptoms have certain improvement, meanwhile, X piece no significant difference before and after treatment；
Invalid：Clinical symptoms improvement is inconspicuous, meanwhile, X piece no significant difference before and after treatment；
Relatively four groups of clinical therapeutic efficacy, result is as follows：
(1) take the patient of the absorption dust discharge Chinese herbal and crude drugs preparationses of embodiment 1 preparation, carry out clinical observation, result is as follows：
Patient 15 before the pneumoconiosis I phase, are clearly better 12 after treatment, take a turn for the better 2,1 invalid；
Pneumoconiosis I phase patient 45, is clearly better 35 after treatment, take a turn for the better 6,4 invalid；
Pneumoconiosis II phase patient 30, is clearly better 25 after treatment, take a turn for the better 5,0 invalid；
Pneumoconiosis III phase patient 15, is clearly better 13 after treatment, take a turn for the better 1,1 invalid.
This shows that present invention absorption dust discharge Chinese herbal and crude drugs preparationses have significant therapeutic effect to various Pneumoconiosis Patients.
(2) take the patient of the Chinese medicine preparation of comparative example 1 preparation, carry out clinical observation, result is as follows：
Patient 15 before the pneumoconiosis I phase, are clearly better 4 after treatment, take a turn for the better 6,5 invalid；
Pneumoconiosis I phase patient 45, is clearly better 11 after treatment, take a turn for the better 28,6 invalid；
Pneumoconiosis II phase patient 30, is clearly better 6 after treatment, take a turn for the better 21,3 invalid；
Pneumoconiosis III phase patient 15, is clearly better 4 after treatment, take a turn for the better 8,3 invalid.
This shows only limited to the therapeutic effect of various Pneumoconiosis Patients with Chinese herbal and crude drugs preparationses, and dust discharge effect is not notable.
(3) take the patient of the colloid agent of comparative example 2 preparation, carry out clinical observation, result is as follows：
Patient 15 before the pneumoconiosis I phase, are clearly better 8 after treatment, take a turn for the better 6,1 invalid；
Pneumoconiosis I phase patient 45, is clearly better 24 after treatment, take a turn for the better 12,9 invalid；
Pneumoconiosis II phase patient 30, is clearly better 14 after treatment, take a turn for the better 11,5 invalid；
Pneumoconiosis III phase patient 15, is clearly better 7 after treatment, take a turn for the better 7,1 invalid.
This shows only there is certain therapeutic effect with colloid agent to various Pneumoconiosis Patients, but not as present invention preparation
Absorption dust discharge Chinese herbal and crude drugs preparationses therapeutic effect notable.
(4) take the patient of the Chinese herbal microecological preparation of comparative example 3 preparation, carry out clinical observation, result is as follows：
Patient 15 before the pneumoconiosis I phase, are clearly better 8 after treatment, take a turn for the better 4,3 invalid；
Pneumoconiosis I phase patient 45, is clearly better 26 after treatment, take a turn for the better 13,6 invalid；
Pneumoconiosis II phase patient 30, is clearly better 20 after treatment, take a turn for the better 6,4 invalid；
Pneumoconiosis III phase patient 15, is clearly better 8 after treatment, take a turn for the better 6,1 invalid.
This shows that Chinese herbal microecological preparation has certain therapeutic effect to various Pneumoconiosis Patients, but is not so good as the present invention
The therapeutic effect of the absorption dust discharge Chinese herbal and crude drugs preparationses of preparation is notable.
From above-mentioned clinical test results, Chinese medicine preparation or the therapeutic effect of colloid agent is only used to be not so good as present invention absorption
The therapeutic effect of dust discharge Chinese herbal and crude drugs preparationses is good, this result show in the absorption dust discharge Chinese herbal and crude drugs preparationses of the present invention medicinal herb componentses with
There is synergistic function between colloid composition, improve the prevention and treatment effect to pneumoconiosis.
To sum up, the pharmaceutical preparation that the absorption dust discharge Chinese herbal and crude drugs preparationses of present invention preparation are prepared than comparative example 1～3 has more preferably
Dust discharge therapeutic effect, meanwhile, the present invention preparation Chinese herbal medicine preparation easily prepare, storage and transport, easy to use, be worth pushing away
Extensively.
Claims (6)
1. a kind of absorption dust discharge Chinese herbal and crude drugs preparationses are it is characterised in that be made up of the raw material of following weight percentage：Ganoderma 0.1 ~
1%th, Poria 0.1 ~ 1%, Radix Asparagi 0.1 ~ 1%, the Radix Astragali 0.1 ~ 1%, Herba Dendrobii 0.1 ~ 1%, Bulbus Fritillariae Cirrhosae 0.1 ~ 1%, Folium Eriobotryae 0.1 ~ 1%, Radix Codonopsis
0.1 ~ 1%, Pericarpium Citri Reticulatae 0.1 ~ 1%, Radix Isatidis 0.1 ~ 1%, Fructus Schisandrae Chinensis 0.1 ~ 1%, Semen Trichosanthis 0.1 ~ 1%, Flos Lonicerae 0.1 ~ 1%, Fructus Alpiniae Oxyphyllae 0.1
~ 1%, Semen Armeniacae Amarum 0.1 ~ 1%, Rhizoma Zingiberis Recenss 0.1 ~ 1%, Radix Glycyrrhizae 0.1 ~ 1%, Fructus Momordicae 0.1 ~ 1%, Flos lupuli (Flos Humuli Lupuli) 0.1 ~ 1%, mature vinegar 0.1 ~ 1%,
Mentholum 0.1 ~ 1%, Sal 0.1 ~ 1%, propolis 0.01 ~ 0.1%, xanthan gum 0.01 ~ 0.1%, guar gum 0.01 ~ 0.1%, gelatin
0.01 ~ 0.1%, sodium alginate 0.01 ~ 0.1%, agar 0.01 ~ 0.1%, glucosan 0.01 ~ 0.1%, pectin 0.01 ~ 0.1%, Mel 1
~ 20%, maltose 1 ~ 10%, syrup 30 ~ 50%, balance of water.
2. absorption dust discharge Chinese herbal and crude drugs preparationses as claimed in claim 1 are it is characterised in that raw material by following weight percentage
Make：Ganoderma 0.1 ~ 0.5%, Poria 0.1 ~ 0.5%, Radix Asparagi 0.1 ~ 0.5%, the Radix Astragali 0.1 ~ 0.5%, Herba Dendrobii 0.1 ~ 0.5%, Bulbus Fritillariae Cirrhosae
0.1 ~ 0.5%, Folium Eriobotryae 0.1 ~ 0.5%, Radix Codonopsis 0.1 ~ 0.5%, Pericarpium Citri Reticulatae 0.1 ~ 0.5%, Radix Isatidis 0.1 ~ 0.5%, Fructus Schisandrae Chinensis 0.1 ~
0.5%th, Semen Trichosanthis 0.1 ~ 0.5%, Flos Lonicerae 0.1 ~ 0.5%, Fructus Alpiniae Oxyphyllae 0.1 ~ 0.5%, Semen Armeniacae Amarum 0.1 ~ 0.5%, Rhizoma Zingiberis Recenss 0.1 ~ 0.5%,
Radix Glycyrrhizae 0.1 ~ 0.5%, Fructus Momordicae 0.1 ~ 0.5%, Flos lupuli (Flos Humuli Lupuli) 0.1 ~ 0.5%, mature vinegar 0.1 ~ 0.5%, Mentholum 0.1 ~ 0.5%, Sal
0.1 ~ 0.5%, propolis 0.01 ~ 0.05%, xanthan gum 0.01 ~ 0.05%, guar gum 0.01 ~ 0.05%, gelatin 0.01 ~ 0.05%, sea
Sodium alginate 0.01 ~ 0.05%, agar 0.01 ~ 0.05%, glucosan 0.01 ~ 0.05%, pectin 0.01 ~ 0.05%, Mel 1 ~ 10%, wheat
Bud sugar 1 ~ 5%, syrup 30-50%, balance of water.
3. a kind of preparation method of the absorption dust discharge Chinese herbal and crude drugs preparationses described in claim 1 or 2 is it is characterised in that take each raw material
Mix homogeneously, heating infusion is obtained serosity；Serosity is filtered, sterilizing, obtain final product described absorption dust discharge Chinese herbal and crude drugs preparationses.
4. the preparation method of absorption dust discharge Chinese herbal and crude drugs preparationses as claimed in claim 3 is it is characterised in that the temperature of described heating
For 80 ~ 100 DEG C.
5. the preparation method of absorption dust discharge Chinese herbal and crude drugs preparationses as claimed in claim 4 is it is characterised in that the time of described heating
For 1 ~ 6 hour.
6. the preparation method of absorption dust discharge Chinese herbal and crude drugs preparationses as claimed in claim 3 is it is characterised in that also include serosity goes out
It is contained in spray bottle after bacterium.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510953666.3A CN105477625B (en) | 2015-12-19 | 2015-12-19 | A kind of absorption dust discharge Chinese herbal and crude drugs preparationses and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510953666.3A CN105477625B (en) | 2015-12-19 | 2015-12-19 | A kind of absorption dust discharge Chinese herbal and crude drugs preparationses and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105477625A CN105477625A (en) | 2016-04-13 |
| CN105477625B true CN105477625B (en) | 2017-03-08 |
Family
ID=55665131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510953666.3A Active CN105477625B (en) | 2015-12-19 | 2015-12-19 | A kind of absorption dust discharge Chinese herbal and crude drugs preparationses and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105477625B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110840829A (en) * | 2019-09-10 | 2020-02-28 | 安徽相王医疗健康股份有限公司 | Dust-washing lung liquid and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306839A (en) * | 2014-09-29 | 2015-01-28 | 青岛康合伟业商贸有限公司 | Traditional Chinese medicine composition |
-
2015
- 2015-12-19 CN CN201510953666.3A patent/CN105477625B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306839A (en) * | 2014-09-29 | 2015-01-28 | 青岛康合伟业商贸有限公司 | Traditional Chinese medicine composition |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105477625A (en) | 2016-04-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1857707A (en) | Chinese medicine mixture for treating infantile dyspneic cough | |
| CN105963452A (en) | Traditional Chinese medicine patch for treating infantile cold cough and preparation method thereof | |
| CN109350718A (en) | Clearing damp Chinese medicine composition and preparation method thereof | |
| CN104381703A (en) | Dog food and preparation method thereof | |
| CN104491356A (en) | Traditional Chinese medicine composition for treating swollen sore throat and chronic pharyngitis | |
| CN1608654A (en) | Chinese medicine for treating intrapulmonic infection and SARS | |
| CN102988649B (en) | Medicament for treating chronic bronchitis and preparation method of medicament | |
| CN105477625B (en) | A kind of absorption dust discharge Chinese herbal and crude drugs preparationses and preparation method thereof | |
| CN111643646A (en) | Traditional Chinese medicine preparation for preventing and treating new coronary pneumonia and preparation method and application thereof | |
| CN103263654B (en) | Medicine for treating lobar pneumonia and preparation method thereof | |
| CN104274682A (en) | Traditional Chinese medicine composition for treating coal workers' pneumoconiosis and preparation method of traditional Chinese medicine composition | |
| CN104435753A (en) | Sugar-free traditional Chinese medicinal buccal tablet for treating sphagitis | |
| CN106912652A (en) | A kind of throat-clearing lung-moistening Se rich tea and preparation method thereof | |
| CN112121116A (en) | Natural plant active factor antibacterial atomizing agent and preparation method thereof | |
| CN112353902A (en) | Throat medicine blowing and tissue regeneration promoting powder and preparation method and application thereof | |
| CN112168947A (en) | Traditional Chinese medicine composition for treating pneumonia and preparation method thereof | |
| CN104547576A (en) | Medicine for relieving postoperative pain of nose endoscopic operation | |
| CN105311602B (en) | A kind of Chinese medicine composition of prevention asthma in children | |
| CN107648569A (en) | A kind of relieving cough and reducing sputum tablet of Chinese medicine and preparation method thereof | |
| CN104707008B (en) | A kind of composite drug and preparation method for preventing chickens respiratory disease | |
| CN108635379A (en) | A kind of wood frog's fallopian tube tablet for treating acute/chronic pharyngitis and respiratory tract infection, strengthen immunity | |
| CN106421573A (en) | Drug for treating cough and preparation method thereof | |
| CN106389796A (en) | Traditional Chinese medicine preparation for treating cold in children and preparation method thereof | |
| CN102038049A (en) | Health protection tea for treating intractable bronchitis and preparation method thereof | |
| CN106511812A (en) | Medicine for treating common cold and preparation method of medicine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |