CN105456041B - Toothpaste containing particles and transparent viscous object - Google Patents
Toothpaste containing particles and transparent viscous object Download PDFInfo
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- CN105456041B CN105456041B CN201510916544.7A CN201510916544A CN105456041B CN 105456041 B CN105456041 B CN 105456041B CN 201510916544 A CN201510916544 A CN 201510916544A CN 105456041 B CN105456041 B CN 105456041B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
Abstract
The invention discloses toothpaste containing particles and a transparent viscous object, wherein the particles are suspended in the transparent viscous object, the particles comprise an abrasive, a humectant, a foaming agent, a thickening agent, an effective component, an appearance regulator, a flavoring agent, a stabilizer, a preservative, a spice and deionized water, the thickening agent in the particles accounts for 1.0-10.0% of the mass of deionized water, the deionized water accounts for 13.0-59.0% of the total mass of the particles, the transparent viscous object comprises the humectant, the thickening agent, the stabilizer, the preservative, the effective component and the deionized water, the thickening agent in the transparent viscous object accounts for 0.1-1.7% of the mass of the deionized water, the deionized water accounts for 47.0-99.4% of the total mass of the transparent viscous object, and the appearance regulator is a non-water-soluble appearance regulator. The transparent viscous substance can make the particles suspended uniformly, and do not settle and dissolve out. The particles have good stability in transparent viscous objects and do not dissolve, break and separate out.
Description
Technical Field
The invention belongs to the technical field of daily chemicals, and particularly relates to toothpaste containing particles and transparent viscous objects.
Background
Since the 21 st century, with the continuous change of living habits and tastes of people, the requirements of consumers on toothpaste, an oral cavity cleaning product essential in the life, are higher and higher, and to some extent, only attention is paid to tooth cleaning in the past, the oral cavity cleaning product gradually develops towards the direction of pursuing the taste of the toothpaste, and then the oral cavity cleaning product develops towards multiple functions and all-round. People not only meet the basic needs of oral health, but also have raised the experience of tooth brushing as a psychological factor, and the personalized requirements on toothpaste are stronger and stronger. Good product aesthetic effect plays an important role in improving the acceptance and use frequency of the product of consumers.
However, most of the existing toothpastes on the market are solid, transparent or colored toothpastes, the appearance is improved by adding some particles, tablets or mica and other substances into the toothpaste contents, the effects carried by the particles, tablets and glittering powder are single, the particles are usually coated with some extracts or cooling agents and the like, and the particles are more used as a raw material for beautifying the appearance.
In addition, the existing toothpaste package is generally a single tube package, a cover needs to be opened when the toothpaste package is used, the toothpaste is squeezed to the toothbrush by hands, then the cover is closed, the taking amount cannot be constant, and the use convenience is limited. Meanwhile, the existing toothpaste has relatively single mouthfeel due to the problems of limited compatibility and mouthfeel of the formula.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides toothpaste containing particles and a transparent viscous object, wherein the transparent viscous object can enable the particles to be uniformly suspended, and the particles are not settled and dissolved out; the particles have good stability in transparent viscous objects and do not dissolve, break and separate out.
In order to achieve the purpose, the invention adopts the following technical scheme:
a toothpaste containing particles and a transparent viscous object, wherein the particles are suspended in the transparent viscous object, the particles comprise an abrasive, a humectant, a foaming agent, a thickening agent, an effective component, an appearance regulator, a flavoring agent, a stabilizer, a preservative, a spice and deionized water, the thickening agent in the particles accounts for 1.0-10.0% of the mass of deionized water, the deionized water accounts for 13.0-59.0% of the total mass of the particles, the transparent viscous object comprises the humectant, the thickening agent, the stabilizer, the preservative, the effective component and the deionized water, the thickening agent in the transparent viscous object accounts for 0.1-1.7% of the mass of the deionized water, the deionized water accounts for 47.0-99.4% of the total mass of the transparent viscous object, and the appearance regulator is a non-water-soluble appearance regulator; the thickening agent in the particles is selected from one or more of gellan gum, sodium alginate, agar, xanthan gum, carrageenan and carbomer; the thickening agent in the transparent viscous object is selected from one or more of gellan gum, carbomer, carrageenan, xanthan gum and sodium carboxymethylcellulose; the volume ratio of the total volume of the particles to the total volume of the transparent viscous object is 1: (0.5-5), the average volume of the particles is 4X 10-9Cubic meter to 5 x 10-7Cubic meter, the shape of the particulate matter is one or more of irregular sphere, regular sphere, irregular polyhedron and regular polyhedron(ii) a The preparation method of the toothpaste comprises the following steps of firstly preparing particles and a transparent viscous object respectively, and then mixing and canning the particles and the transparent viscous object into the transparent viscous suspended particles:
the following method was used to prepare the granules: adding the functional components, the flavoring agent, the stabilizer and the preservative into deionized water, stirring until the functional components are completely dissolved to prepare a water phase solution, adding the humectant into the water phase solution, stirring and dissolving to prepare a liquid phase solution, weighing the abrasive, the thickening agent and the foaming agent, uniformly mixing, adding the mixture into the liquid phase solution, and quickly stirring and homogenizing for 20-60 minutes; adding weighed appearance regulator and essence into the mixture, stirring, and degassing to obtain spherical paste; heating the materials remained for preparing the spherical toothpaste in a closed environment to 60-90 ℃ to obtain a fluid liquid, controlling the optimal viscosity to be in the range of 1000-2000cP after heating, dripping silicone oil, pure water or calcium chloride liquid with the temperature of (-10) -10 ℃ into the fluid liquid, and preparing the uniform spherical toothpaste with the diameter of 1-10mm by using a solid pill dripping machine;
a transparent viscous object was prepared by the following method: weighing part of water from the total water amount of the formula, slowly adding the thickening agent into deionized water under the stirring condition, and stirring for 30-60 minutes to prepare a hydrated gum solution for later use; adding stabilizer, effective components and antiseptic into partial water, stirring to obtain water phase solution, adding humectant, and stirring to obtain liquid phase solution; mixing the prepared hydrated gel solution and the liquid phase solution, stirring for 30-60 minutes, and degassing to obtain clear transparent gel.
Preferably, the volume ratio of the total volume of the particulate matter to the total volume of the transparent viscous object is 1: (0.5-5), the average volume of the particles is 4X 10-9Cubic meter to 5 x 10-7Cubic meter.
Preferably, the shape of the particulate matter is one or more of irregular spheres, regular spheres, irregular polyhedrons and regular polyhedrons.
Particularly preferably, the particulate matter is in the shape of one or more of a sphere, an ellipsoid, a cube and a pyramid.
Preferably, the water-insoluble appearance regulator is selected from one or more of mica, water-insoluble pigment and water-insoluble color paste.
Further preferably, the water-insoluble pigment is one or more selected from titanium dioxide, oil-soluble blue, oil-soluble yellow and oil-soluble red.
Further preferably, the water-insoluble color paste is selected from one or more of red lake, yellow lake, blue lake and green lake.
Preferably, the particulate matter comprises the following components in parts by weight:
preferably, the transparent viscous substance comprises the following components in parts by weight:
further preferably, the functional components in the granules are selected from one or more of sodium phytate, pyrophosphate, pearl powder, hydroxyapatite, zinc citrate, cetylpyridinium chloride, magnolol extract, fluoride, xylitol, erythritol, potassium nitrate, strontium chloride, hydroxyapatite, paeonol, tranexamic acid, 0-cymene-5-alcohol, ilex cortex extract and honeysuckle extract; the abrasive is selected from one or more of natural calcium carbonate, silicon dioxide, dihydrated monocalcium phosphate, aluminum hydroxide, light calcium carbonate, anhydrous calcium hydrophosphate, anhydrous calcium pyrophosphate or calcium hydroxy phosphate; the humectant is selected from one or more of sorbitol, glycerol, propylene glycol and polyethylene glycol; the foaming agent is selected from one or more of sodium lauryl sulfate, sodium lauroyl sarcosinate, betaine, alkyl polyglucoside and the like; the flavoring agent is selected from one or more of saccharin sodium, sucralose, stevioside, aspartame, acesulfame potassium and salt; the stabilizer is selected from one or more of pyrophosphate, sodium hydroxide, citrate and sodium hydrogen phosphate; the preservative is selected from one or more of methyl hydroxybenzoate, propyl hydroxybenzoate, benzoic acid, sodium benzoate, sorbic acid and potassium sorbate; the spice is selected from one or more of essence with mint flavor, spearmint flavor, flower fragrance flavor, fruit fragrance flavor and the like; the thickening agent is one or more selected from gellan gum, sodium alginate, agar, xanthan gum, carrageenan and carbomer.
Further preferably, the humectant in the transparent viscous object is selected from one or more of sorbitol, glycerol, propylene glycol and polyethylene glycol; the effective components are selected from one or more of cetylpyridinium chloride, 0-cymene-5-alcohol, magnolol extract, folium Artemisiae Argyi extract and grapefruit extract; the preservative is selected from one or more of methyl hydroxybenzoate, propyl hydroxybenzoate, benzoic acid, sodium benzoate, sorbic acid and potassium sorbate; the thickening agent is selected from one or more of gellan gum, carbomer, carrageenan, xanthan gum and sodium carboxymethylcellulose; the stabilizer is one or more selected from pyrophosphate, sodium hydroxide, citrate, sodium hydrogen phosphate, calcium chloride and the like.
The transparent sticky object also comprises a pigment, and the pigment accounts for 0.01-0.1% of the mass of the sticky object. The pigment is preferably a water-soluble pigment.
The invention also provides a preparation method of the toothpaste, which comprises the steps of respectively preparing the particles and the transparent viscous object, and then mixing and canning the particles and the transparent viscous object to form the transparent viscous suspended particle toothpaste. The particles are preferably spherical particles. The transparent viscous object is preferably a transparent jelly.
Preferably, the spherical particles are prepared by a one-step method, which specifically comprises the following steps: adding the functional components, flavoring agent, stabilizer and antiseptic into deionized water, stirring to dissolve completely, and making into water phase solution. Adding humectant into the water phase solution, stirring and dissolving to obtain liquid phase solution. The abrasive, the thickening agent and the foaming agent are weighed and then evenly mixed, added into the liquid phase solution, and rapidly stirred and homogenized for 20-60 minutes. Adding weighed appearance regulator and essence, stirring, and degassing to obtain spherical paste. Heating the prepared toothpaste in a closed environment to 60-90 deg.C to obtain a fluid liquid, controlling the optimum viscosity to be within the range of 1000-2000cP, adding dropwise silicone oil, pure water or calcium chloride solution at (-10) -10 deg.C into the fluid liquid, and making into uniform spherical toothpaste with diameter of 1-10mm by using a solid dripping pill machine.
Preferably, the transparent viscous object is prepared by the following method, which specifically comprises the following steps: weighing part of water from the total water amount in the formula, slowly adding the thickening agent into deionized water under the stirring condition, and stirring for 30-60 minutes to prepare a hydrated gum solution for later use. Adding stabilizer, effective components and antiseptic into partial water, stirring to obtain water phase solution, adding humectant, and stirring to obtain liquid phase solution. Mixing the prepared hydrated gel solution and the liquid phase solution, stirring for 30-60 minutes, and degassing to obtain clear transparent gel.
Preferably, the method for preparing the toothpaste containing the spherical particles and the transparent viscous substance comprises the steps of mixing and degassing the prepared spherical particles and the transparent viscous substance, and filling the mixture into a transparent pump tube together.
The toothpaste provided by the invention not only endows the toothpaste with a novel and attractive appearance, but also can realize multi-taste experience and multi-effect realization of the oral cavity, and meets the use requirements of modern people on diversified effects of the toothpaste. Meanwhile, with the help of the novel pump type packing material, the use convenience of the product is improved, and the aesthetic experience of a user is improved with the help of the innovative appearance and the innovative package of the product, so that the consumers can feel hot from the mind and mind to brush teeth to maintain the oral health.
The toothpaste composition is filled into the transparent pump type packaging material, so that the excellent appearance visual effect can be presented, the pump type paste taking is sanitary and convenient to use, and the particulate matter and the transparent viscous object can be combined in different mouthfeel formulas, so that unique mouthfeel experience is brought to consumers.
Compared with the prior art, the invention has the following beneficial effects:
1. in the toothpaste containing the particles and the transparent viscous object, the particles have good stability in the transparent viscous object and are not dissolved or separated out. The transparent viscous object adopts a water-soluble system, the particles prepared by the water-insoluble appearance regulator are water-insoluble, the thickening agent adopted during the preparation of the particles accounts for 1.0-10.0% of the mass of deionized water, the deionized water accounts for 13.0-59.0% of the total mass of the composition, and the adopted thickening agent and the appearance regulator can act together to ensure that the particles are not dissolved and separated out in the transparent viscous object.
Meanwhile, the compatibility of the particles and the transparent viscous object is good, and the particles can not be dissolved out and broken in the transparent viscous object.
2. The transparent viscous object of the invention controls the suspension force of the transparent viscous object by adopting gellan gum and/or carbomer and/or carrageenan and/or xanthan gum and/or sodium carboxymethylcellulose, particularly gellan gum and carbomer which account for 0.1-1.7% of the mass of deionized water, and deionized water accounts for 47.0-99.4% of the mass of the total raw materials of the composition, so that particles can be uniformly suspended without sedimentation and dissolution.
3. The toothpaste of the invention comprises particulate matter and transparent viscous material, which may each have different efficacy and different mouthfeel. When the compound premix is used, the particles and the transparent viscous object are extruded and mixed together, so that the effect synergy and the taste superposition are realized.
4. In the toothpaste containing the particles and the transparent viscous object, the particles can have different colors and shapes, so that the color or shape diversification of the toothpaste can be realized, and the attractive effect is achieved.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to examples, but the scope of the present invention is not limited to the examples.
The formulation of the spherical particles and the formulation of the transparent viscous mass are detailed in table 1 below.
TABLE 1 formulation of spherical particles and formulation of transparent viscous bodies
TABLE 2 formulation of spherical particles and formulation of transparent viscous bodies
TABLE 3 formulation of spherical particles and formulation of transparent viscous bodies
Preparing spherical particles: the raw materials are prepared according to the formulas of the examples and the comparative examples in the tables 1 to 3, and are respectively prepared by adopting a one-step method, which specifically comprises the following steps:
(1) adding crystalline sodium pyrophosphate, sodium phytate, sodium saccharin, cetylpyridinium chloride and sodium benzoate into deionized water, wherein in example 5, the sodium phytate is also added, and stirring is carried out until the sodium phytate is completely dissolved to prepare an aqueous phase solution. Adding sorbitol and polyethylene glycol into the aqueous phase solution, stirring and dissolving to obtain liquid phase solution.
(2) Weighing hydrated silica, carrageenan, xanthan gum and sodium lauryl sulfate, uniformly mixing, adding into the liquid phase solution, and rapidly stirring and homogenizing for 20 minutes.
(3) Adding weighed oil-soluble blue and essence, stirring for 15 min, and degassing to obtain spherical paste. Heating the prepared toothpaste in a closed environment at 60 deg.C to obtain a fluid liquid, controlling viscosity to 1000cP, adding dropwise-8 deg.C silicone oil into the fluid liquid, and making into uniform spherical particles with diameter of 3mm with a solid dripping pill machine.
Preparation of a transparent viscous object: the raw materials were prepared according to the formulations of the examples and comparative examples in table 1, and were prepared by the following methods, respectively, including the following steps:
(1) and slowly adding carbomer into deionized water under stirring, and stirring for 30 minutes to prepare a hydrated gum solution for later use.
(2) Adding sodium hydroxide, 0-cymene-5-ol, grapefruit extract, and methyl hydroxybenzoate into part of water, stirring to obtain water phase solution, adding sorbitol and glycerol, and stirring to obtain liquid phase solution.
(3) Mixing the prepared hydrated gel solution and the liquid phase solution, stirring for 30 minutes, degassing, and preparing into transparent gel.
Preparing toothpaste: the prepared spherical particles and transparent gel are mixed and degassed according to the formula of each example and comparative example in the table 1, and then the mixture is filled into a transparent pump tube together, so that the toothpaste containing the spherical particles and the transparent gel is prepared respectively.
The toothpastes prepared in examples 1 to 5 and comparative examples 1 to 6 were respectively tested under the same conditions, and the test results are shown in Table 4, respectively, as follows.
TABLE 4 measurement results
The results show that the granules of the toothpaste prepared in the example 1 and the toothpaste prepared in the comparative example 1 are round, compared with the pigment of the comparative example 1, the pigment of the toothpaste prepared in the example 1 is not dissolved or separated due to the addition of the pigment 'oil soluble blue' which is insoluble in water, the stability is good, the pigment is not dissolved or separated at normal temperature and 45 ℃ after being placed for 3 months, meanwhile, the granules can be stably suspended in the transparent gel, the granules are not deformed, and the toothpaste can play a good role in cleaning and protecting teeth. After the toothpaste of the comparative example 1 is prepared, the water-soluble pigment is added into the particles, so that the pigment is dissolved and separated out by 50 percent, the pigment is dissolved and separated out by 90 percent after the toothpaste is placed for 1 month, and the deformation effect is obvious along with the prolonging of the placing time.
The toothpaste prepared in comparative example 2 had 95% of the particulates settled and were not effectively suspended in clear gel due to the disproportionate proportion of deionized water in clear gel. In addition, in comparative example 2, the colloid content was not in the appropriate range, the formed particles were not uniform and not rounded, and the forming rate was only 30%.
The toothpaste prepared in example 3 was too hard to be extruded in use because the amount of deionized water was too small compared to the toothpaste prepared in comparative example 3.
The toothpaste prepared in example 4 contained only spherical particles and no clear gel, compared to the toothpaste prepared in comparative example 4. More than 98% of the spherical particles prepared in example 4 were stably suspended in transparent gel, while the toothpaste prepared in comparative example 4 had all the spherical particles stacked together, and when the toothpaste prepared in example 4 and the toothpaste prepared in comparative example 4 were used separately in a bottle with a pump tube, the remaining unused spherical particles in example 4 were intact and had a breakage rate of 0 since the toothpaste was extruded through the pump tube each time it was used, while the remaining unused spherical particles in comparative example 4 were easily broken by air due to the absence of transparent gel to cushion the pressure of air during extrusion, and the breakage rate was higher as the standing time was longer.
In comparison with the toothpaste prepared in comparative example 5, since the volume ratio of the transparent gel to the spherical particles is 0.2:1, when the toothpaste is used in comparative example 4, the remaining unused spherical particles in comparative example 5 are easily broken by air extrusion because there is not enough transparent gel to buffer the pressure of air during extrusion, and the broken rate is higher as the time for standing is longer. .
The toothpaste prepared in example 5 and the toothpaste prepared in comparative example 6 were each subjected to a whitening test using an SP62 colorimeter under the same conditions, according to which the international commission on illumination (CIE) L a b standard colorimetric system is the most commonly used color system in dentistry, L represents the visual perception value of 0 to 100, and the larger value is close to white, and the smaller value is close to black. The effect of the toothpaste on removing the exogenous stains can be reflected by recording the change of the L value of the teeth before and after brushing. The test results are shown in Table 5 below.
Table 5 whitening test data
The test results in table 5 show that the relative standard deviation RSD of Δ L of the experimental test is less than 30%, which indicates that the experimental results of the whitening test method have good precision. Meanwhile, the Δ L values of the toothpaste of the control group and the toothpaste of the experimental group are 2.69 ± 2.18 and 2.69 ± 2.18, respectively, and the two have significant differences, which indicates that the whitening effect of the toothpaste prepared in example 5 is better than that of the toothpaste prepared in the control group 6.
The toothpaste prepared in example 6 and the toothpaste prepared in comparative example 7 were subjected to the bacteriostatic effect test under the same conditions, and the test results are shown in table 6, respectively, as follows.
TABLE 6 results of antibacterial analysis
The above results show that the toothpaste prepared in example 6 has higher activity of the effective component due to the addition of the transparent gel, and the bacteriostasis rate is more than 99.9% compared with the toothpaste prepared in comparative example 7.
Variations and modifications to the above-described embodiments may occur to those skilled in the art, which fall within the scope and spirit of the above description. Therefore, the present invention is not limited to the specific embodiments disclosed and described above, and some modifications and variations of the present invention should fall within the scope of the claims of the present invention. Furthermore, although specific terms are employed herein, they are used in a generic and descriptive sense only and not for purposes of limitation.
Claims (9)
1. A toothpaste containing particulate matter and transparent viscous substance, and its preparation methodThe method is characterized in that particles are suspended in a transparent viscous object, the particles comprise an abrasive, a humectant, a foaming agent, a thickening agent, an effective component, an appearance regulator, a flavoring agent, a stabilizer, a preservative, a spice and deionized water, the thickening agent in the particles accounts for 1.0-10.0% of the mass of deionized water, the deionized water accounts for 13.0-59.0% of the total mass of the particles, the transparent viscous object comprises the humectant, the thickening agent, the stabilizer, the preservative, the effective component and the deionized water, the thickening agent in the transparent viscous object accounts for 0.1-1.7% of the mass of the deionized water, the deionized water accounts for 47.0-99.4% of the total mass of the transparent viscous object, and the appearance regulator is a non-water-soluble appearance regulator; the thickening agent in the particles is selected from one or more of gellan gum, sodium alginate, agar, xanthan gum, carrageenan and carbomer; the thickening agent in the transparent viscous object is selected from one or more of gellan gum, carbomer, carrageenan, xanthan gum and sodium carboxymethylcellulose; the volume ratio of the total volume of the particles to the total volume of the transparent viscous object is 1: (0.5-5), the average volume of the particles is 4X 10-9Cubic meter to 5 x 10-7Cubic meter, the shape of the particles is regular spheres; the preparation method of the toothpaste comprises the following steps of firstly preparing particles and a transparent viscous object respectively, and then mixing and canning the particles and the transparent viscous object into the transparent viscous suspended particles:
the following method was used to prepare the granules: adding the functional components, the flavoring agent, the stabilizer and the preservative into deionized water, stirring until the functional components are completely dissolved to prepare a water phase solution, adding the humectant into the water phase solution, stirring and dissolving to prepare a liquid phase solution, weighing the abrasive, the thickening agent and the foaming agent, uniformly mixing, adding the mixture into the liquid phase solution, and quickly stirring and homogenizing for 20-60 minutes; adding weighed appearance regulator and essence into the mixture, stirring, and degassing to obtain spherical paste; heating the material remained for preparing the spherical paste to 60-90 ℃ in a closed environment until the material is fluid liquid, controlling the optimal viscosity to be in the range of 1000-2000cP after heating, dripping silicone oil, pure water or calcium chloride liquid with the temperature of minus 10-10 ℃ into the fluid liquid, and preparing uniform spherical particles with the diameter of 1-10mm by using a solid pill dropping machine;
a transparent viscous object was prepared by the following method: weighing part of water from the total water amount of the formula, slowly adding the thickening agent into deionized water under the stirring condition, and stirring for 30-60 minutes to prepare a hydrated gum solution for later use; adding stabilizer, effective components and antiseptic into partial water, stirring to obtain water phase solution, adding humectant, and stirring to obtain liquid phase solution; mixing the prepared hydrated gel solution and the liquid phase solution, stirring for 30-60 minutes, and degassing to obtain clear transparent gel.
2. The toothpaste of claim 1, wherein said water insoluble appearance modifier is selected from one or more of mica, water insoluble pigments, water insoluble mill base.
3. The toothpaste of claim 2, wherein said water insoluble pigment is selected from one or more of titanium dioxide, oil soluble blue, oil soluble yellow, and oil soluble red.
4. The toothpaste of claim 2, wherein the water insoluble color paste is selected from one or more of red lake, yellow lake, blue lake and green lake.
5. The toothpaste according to any one of claims 1 to 4, wherein the particulate component comprises, in parts by weight:
6. the toothpaste according to any one of claims 1 to 4, wherein the transparent viscous mass comprises, in parts by weight:
7. the toothpaste according to claim 5, wherein: the functional components in the particles are selected from one or more of sodium phytate, pyrophosphate, pearl powder, zinc citrate, cetylpyridinium chloride, magnolol extract, fluoride, xylitol, erythritol, potassium nitrate, strontium chloride, hydroxyapatite, paeonol, tranexamic acid, 0-cymene-5-alcohol, ilex pubescens extract and honeysuckle extract; the abrasive is selected from one or more of natural calcium carbonate, silicon dioxide, dihydrated monocalcium phosphate, aluminum hydroxide, light calcium carbonate, anhydrous calcium hydrophosphate, anhydrous calcium pyrophosphate or calcium hydroxy phosphate; the humectant is selected from one or more of sorbitol, glycerol, propylene glycol and polyethylene glycol; the foaming agent is selected from one or more of sodium lauryl sulfate, sodium lauroyl sarcosinate, betaine and alkyl polyglucoside; the flavoring agent is selected from one or more of saccharin sodium, sucralose, stevioside, aspartame, acesulfame potassium and salt; the stabilizer is selected from one or more of pyrophosphate, sodium hydroxide, citrate and sodium hydrogen phosphate; the preservative is selected from one or more of methyl hydroxybenzoate, propyl hydroxybenzoate, benzoic acid, sodium benzoate, sorbic acid and potassium sorbate; the spice is selected from one or more of mint, spearmint, floral and fruity essences.
8. The toothpaste of claim 6, wherein said humectant in said transparent viscous material is selected from one or more of sorbitol, glycerin, propylene glycol, polyethylene glycol; the effective components are selected from one or more of cetylpyridinium chloride, 0-cymene-5-alcohol, magnolol extract, folium Artemisiae Argyi extract and grapefruit extract; the preservative is selected from one or more of methyl hydroxybenzoate, propyl hydroxybenzoate, benzoic acid, sodium benzoate, sorbic acid and potassium sorbate; the stabilizer is one or more selected from pyrophosphate, sodium hydroxide, citrate, sodium hydrogen phosphate and calcium chloride.
9. The toothpaste of claim 6, wherein said transparent viscous body further comprises a pigment, said pigment comprising from 0.01% to 0.1% by mass of the viscous body.
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