CN105445052A - Online sampling system for traditional Chinese medicine production process and sampling device - Google Patents
Online sampling system for traditional Chinese medicine production process and sampling device Download PDFInfo
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- CN105445052A CN105445052A CN201510912462.5A CN201510912462A CN105445052A CN 105445052 A CN105445052 A CN 105445052A CN 201510912462 A CN201510912462 A CN 201510912462A CN 105445052 A CN105445052 A CN 105445052A
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- line period
- sampling
- chinese traditional
- traditional medicine
- test tube
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
Abstract
The invention discloses an online sampling system for the traditional Chinese medicine production process and a sampling device. The system comprises a conveyor belt and several sampling tubes. The several sampling tubes are evenly spaced on the conveyor belt. A conveying pipe corresponding to the sampling tubes is arranged above the conveyor belt. A sampling valve and a flowmeter are arranged on the conveying pipe. One side of the conveying pipe is successively provided with a sealing machine, a labeling machine and a printer. The sampling device also comprises a traditional Chinese medicine production tank, a hydraulic pump, a filter, a flow-through cell and a return piping. Through the above mode, the online sampling system for the traditional Chinese medicine production process and the sampling device can realize automatic and quantitative acquisition of samples, sealing and labeling and are simple to operate. By the use of the system and the device, manual errors are eliminated, automation degree is raised, and modeling efficiency is enhanced.
Description
Technical field
The present invention relates to drug production process and analyze detection field, particularly relate to a kind of Chinese Traditional Medicine on-line period system and sampler.
Background technology
Chinese medicine production procedure primarily of extraction, filter, concentrated, alcohol precipitation, absorption, drying, the operation composition such as preparation, and the operations such as extraction main, concentrated, alcohol precipitation and drying are all multivariate, large, the nonlinear complex dynamic systems of disturbance.Therefore need to sample in Chinese Traditional Medicine, thus production run is monitored.
Current sampling process at present more adopts artificial timing sampling, by manual control switch's sample cock, sealing, hand-written label, records sample time etc., there is operate miss, time error, complex operation and can destroy the shortcomings such as sample.Therefore, need the developing direction complying with industrial automation, adopt automatic sampling to substitute hand sampling, eliminate the various errors etc. that operating process produces.
Summary of the invention
The technical matters that the present invention mainly solves is to provide a kind of Chinese Traditional Medicine on-line period system and sampler, conveniently carries out robotization sampling, reduces error, realizes automated production.
For solving the problems of the technologies described above, the technical scheme that the present invention adopts is: provide a kind of Chinese Traditional Medicine on-line period system, comprise: transmit crawler belt and several sampling test tube, described several sampling test tube is disposed in an evenly spaced relation in and transmits on crawler belt, the feed pipe corresponding with sampling test tube is provided with above described transmission crawler belt, described feed pipe is provided with sample valve and flowmeter, described feed pipe side is disposed with capper, labelling machine and printer, and described capper and labelling machine are separately positioned on above the end of sampling test tube.
In a preferred embodiment of the present invention, described Chinese Traditional Medicine on-line period system also comprises control device, and described control device is connected to control it with printer runs with transmission crawler belt, capper, labelling machine respectively.
In a preferred embodiment of the present invention, described labelling machine comprises a mechanical arm, and described printer is positioned at the side of labelling machine.
In a preferred embodiment of the present invention, described sampling test tube is vertically set on respectively and transmits on crawler belt, the opening upwards of described sampling test tube.
In a preferred embodiment of the present invention, the end of described feed pipe is provided with a jet blower, and described jet blower and capper are respectively arranged with a jacking gear.
In a preferred embodiment of the present invention, described control system comprises human-computer interaction interface.
For solving the problems of the technologies described above, the technical scheme that the present invention adopts is: provide a kind of sampler, comprise described Chinese Traditional Medicine on-line period system, described sampler also comprises Chinese medicine and produces tank, hydraulic pump, filtrator, flow cell and return, the two ends of described return produce tank respectively bottom with Chinese medicine is connected with top and forms loop, described hydraulic pump, filtrator, flow cell and Chinese Traditional Medicine on-line period system are successively set on return from top to bottom, described flow cell is connected with the liquid analysis that a near infrared spectrometer carries out flowing through flow cell.
In a preferred embodiment of the present invention, described feed pipe is connected to extraction flow cell carrying out liquid.
In a preferred embodiment of the present invention, described filtrator comprises at least 2 filter sticks be arranged in parallel.
In a preferred embodiment of the present invention, described sampler also comprises a high performance liquid chromatograph.
The invention has the beneficial effects as follows: a kind of Chinese Traditional Medicine on-line period system that the present invention points out and sampler, achieve the automatic collection of sample in Chinese Traditional Medicine, the automatic ration collection of sample, sealing and labeling can be realized, easy and simple to handle, eliminate human error, save human cost, improve and analyze detection efficiency, be applicable to traditional Chinese medicine extraction, concentrated, alcohol precipitation, depositing in water and macroreticular resin elution process, applied widely.
Accompanying drawing explanation
In order to be illustrated more clearly in the technical scheme in the embodiment of the present invention, below the accompanying drawing used required in describing embodiment is briefly described, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings, wherein:
Fig. 1 is the structural representation of a kind of Chinese Traditional Medicine on-line period of the present invention system one preferred embodiment;
Fig. 2 is the structural representation of a kind of sampler of the present invention.
Embodiment
Be clearly and completely described to the technical scheme in the embodiment of the present invention below, obviously, described embodiment is only a part of embodiment of the present invention, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making other embodiments all obtained under creative work prerequisite, belong to the scope of protection of the invention.
Refer to Fig. 1 to Fig. 2, the embodiment of the present invention comprises:
A kind of Chinese Traditional Medicine on-line period system, comprise: transmit crawler belt 1 and several sampling test tube 2, described several sampling test tube 2 is disposed in an evenly spaced relation in and transmits on crawler belt 1, the feed pipe 9 corresponding with sampling test tube 2 is provided with above described transmission crawler belt 1, described feed pipe 9 is provided with sample valve 3 and flowmeter 4, described feed pipe 9 side is disposed with capper 5, labelling machine 6 and printer 7, described capper 5 and labelling machine 6 are separately positioned on above the end of sampling test tube 2, seal one by one.
Described Chinese Traditional Medicine on-line period system also comprises control device 8, and described control device 8 is connected to control it with printer 7 runs with transmission crawler belt 1, capper 5, labelling machine 6 respectively.Described control system 8 comprises human-computer interaction interface, and human-computer interaction interface has detection, checks, inputs, arranges, deletes and communication function, handled easily.
Described labelling machine 6 comprises a mechanical arm, and described printer 7 is positioned at the side of labelling machine 6.Control device 8 controls printer 7 Print Label, and the mechanical arm of labelling machine 6 is attached to after label taking-up on the tube wall of sampling test tube 2.
Described sampling test tube 2 is vertically set on respectively and transmits on crawler belt 1, and the opening upwards of described sampling test tube 2, is convenient to capper 5 and seals.
The end of described feed pipe 9 is provided with a jet blower 91, described jet blower 91 and capper 5 is respectively arranged with a jacking gear, facilitates injection and the sealing of sampling test tube 2.
A kind of sampler, comprise described Chinese Traditional Medicine on-line period system 17, described sampler also comprises Chinese medicine and produces tank 11, hydraulic pump 12, filtrator 13, flow cell 15 and return 16, the two ends of described return 16 produce tank 11 respectively bottom with Chinese medicine is connected with top and forms loop, described hydraulic pump 12, filtrator 13, flow cell 15 and Chinese Traditional Medicine on-line period system 17 are successively set on return 16 from top to bottom, described flow cell 15 is connected with the liquid analysis that a near infrared spectrometer 14 carries out flowing through flow cell 15.
Described feed pipe 9 is connected to extraction flow cell 15 carrying out liquid.
Described filtrator 13 comprises at least 2 filter sticks be arranged in parallel, and avoids filter stick blocked and cannot circulate, and improve job stability, described sampler also comprises a high performance liquid chromatograph, detects.
Obviously, described Chinese Traditional Medicine on-line period system can be dismantled from sampler, is widely used in the processes such as the extraction of Chinese medicine, concentrated, alcohol precipitation and depositing in water.
Embodiment 1:
Chinese Traditional Medicine on-line period system of the present invention is applied to safflower leaching process on-line period process:
(1) in safflower leaching process, the installation site of Chinese Traditional Medicine on-line period system 17 as shown in Figure 2, extract in extractor 11 is through pump 12 and filtrator 13, flow through flow cell 15, get back in extractor 11 by pipeline 16, Chinese Traditional Medicine on-line period system 17 is arranged on flow cell 15; Cut off near infrared spectrometer 14 and the connection of flow cell 15, make near infrared spectrometer 14 not gather the spectrum of flow cell 15;
(2) start control device 8, sample ID is set by human-computer interaction interface: Flos Carthami extract; The distance transmitting each movement of crawler belt 1 is set: 5 centimetres; Being spaced apart between sampling test tube 2: 5 centimetres; Sampling interval time: 5 minutes; The volume of sampling: 10 milliliters;
(3) regulate transmission crawler belt 1, make sampling test tube 2 be positioned at immediately below jet blower 91, prepare sampling;
(4) open sample valve 3, start sampling, start countdown, count down time 5 minutes simultaneously, through flowmeter 4 calculate sample volume reach 10 milliliters time, close sample valve 3, transmit crawler belt 1 move forward 5 centimetres;
(5) sampling test tube 2 after now sampling is positioned at immediately below capper 5, and the sampling test tube 2 after sampling seals by capper 5;
(6), after countdown terminates, open sample valve 3 and start to sample to next sampling test tube, through flowmeter 4 calculate sample volume reach 10 milliliters time, close sample valve 3, transmit crawler belt 1 move forward 5 centimetres, circulation carry out sealing and sampling;
(7) printer 7 Print Label after each sealing, the mechanical arm of labelling machine 6 will be attached on the tube wall of sampling test tube 2 after label taking-up, (supposing to be now 08:10 on September 1st, 2015), and label substance is as follows:
Sample ID: Flos Carthami extract;
Sample number: 1;
Sample time: 2015.09.01.08:05;
Complete the automatic sampling process of safflower leaching process on-line checkingi;
(8) near infrared spectrometer 14 is utilized to gather the near infrared light spectrogram of sample in sampling test tube 2;
(9) high performance liquid chromatograph is used to detect the content of effective constituent hydroxyl radical carthamin yellow carthamus A in sample;
(10) nearly infrared spectrogram and assay result carry out the data processing of Chemical Measurement again, Modling model.
Near infrared spectrum online quality control process:
Recover the connection of near infrared spectrometer 14 and flow cell 15, the near infrared spectrum of extract near infrared spectrometer 14 real time scan flow cell 15, institute's Modling model is applied to safflower leaching process, draw the content of effective constituent in safflower leaching process extract, realize the online quality control of safflower leaching process.
Chinese Traditional Medicine on-line period system 17 is dismountable, may be used for the processes such as the extraction of Chinese medicine, concentrated, alcohol precipitation and depositing in water.
Embodiment 2:
Chinese Traditional Medicine on-line period system of the present invention is applied to Flos Lonicerae extractive solution concentration process:
(1) in Flos Lonicerae extractive solution concentration process, the installation site of Chinese Traditional Medicine on-line period system 17 as shown in Figure 2, extract in extractor 11 is through pump 12 and filtrator 13, flow through flow cell 15, get back in extractor 11 by pipeline 16, Chinese Traditional Medicine on-line period system 17 is arranged on flow cell 15;
(2) start control device 8, sample ID is set by human-computer interaction interface: honeysuckle concentrate; The distance transmitting each movement of crawler belt 1 is set: 3 centimetres; Being spaced apart between sampling test tube 2: 3 centimetres; Sampling interval time: 3 minutes; The volume of sampling: 5 milliliters;
(3) regulate transmission crawler belt 1, make sampling test tube 2 be positioned at immediately below jet blower 91, prepare sampling;
(4) open sample valve 3, start sampling, start countdown, count down time 5 minutes simultaneously, through flowmeter 4 calculate sample volume reach 10 milliliters time, close sample valve 3, transmit crawler belt 1 move forward 5 centimetres;
(5) sampling test tube 2 after now sampling is positioned at immediately below capper 5, and the sampling test tube 2 after sampling seals by capper 5;
(6), after countdown terminates, open sample valve 3 and start to sample to next sampling test tube, through flowmeter 4 calculate sample volume reach 10 milliliters time, close sample valve 3, transmit crawler belt 1 move forward 5 centimetres, circulation carry out sealing and sampling;
(7) printer 7 Print Label after each sealing, the mechanical arm of labelling machine 6 will be attached on the tube wall of sampling test tube 2 after label taking-up, (supposing to be now 08:10 on September 1st, 2015), and label substance is as follows:
Sample ID: honeysuckle concentrate;
Sample number: 1;
Sample time: 2015.09.01.08:07;
Complete the automatic sampling process of Flos Lonicerae extractive solution concentration process.
In sum, a kind of Chinese Traditional Medicine on-line period system that the present invention points out and sampler, easy and simple to handle, error is little, applied widely.
The foregoing is only embodiments of the invention; not thereby the scope of the claims of the present invention is limited; every utilize description of the present invention to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical field, be all in like manner included in scope of patent protection of the present invention.
Claims (10)
1. a Chinese Traditional Medicine on-line period system, comprise: transmit crawler belt and several sampling test tube, described several sampling test tube is disposed in an evenly spaced relation in and transmits on crawler belt, it is characterized in that, the feed pipe corresponding with sampling test tube is provided with above described transmission crawler belt, described feed pipe is provided with sample valve and flowmeter, described feed pipe side is disposed with capper, labelling machine and printer, and described capper and labelling machine are separately positioned on above the end of sampling test tube.
2. Chinese Traditional Medicine on-line period system according to claim 1, it is characterized in that, described Chinese Traditional Medicine on-line period system also comprises control device, and described control device is connected to control it with printer runs with transmission crawler belt, capper, labelling machine respectively.
3. Chinese Traditional Medicine on-line period system according to claim 1, is characterized in that, described labelling machine comprises a mechanical arm, and described printer is positioned at the side of labelling machine.
4. Chinese Traditional Medicine on-line period system according to claim 1, is characterized in that, the end of described feed pipe is provided with a jet blower, and described jet blower and capper are respectively arranged with a jacking gear.
5. Chinese Traditional Medicine on-line period system according to claim 1, is characterized in that, described sampling test tube is vertically set on respectively and transmits on crawler belt, the opening upwards of described sampling test tube.
6. Chinese Traditional Medicine on-line period system according to claim 2, is characterized in that, described control system comprises human-computer interaction interface.
7. a sampler, it is characterized in that, comprise the arbitrary described Chinese Traditional Medicine on-line period system of claim 1 ~ 6, described sampler also comprises Chinese medicine and produces tank, hydraulic pump, filtrator, flow cell and return, the two ends of described return produce tank respectively bottom with Chinese medicine is connected with top and forms loop, described hydraulic pump, filtrator, flow cell and Chinese Traditional Medicine on-line period system are successively set on return from top to bottom, described flow cell is connected with the liquid analysis that a near infrared spectrometer carries out flowing through flow cell.
8. sampler according to claim 7, is characterized in that, described feed pipe is connected to extraction flow cell carrying out liquid.
9. sampler according to claim 7, is characterized in that, described filtrator comprises at least 2 filter sticks be arranged in parallel.
10. sampler according to claim 7, is characterized in that, described sampler also comprises a high performance liquid chromatograph.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510912462.5A CN105445052A (en) | 2015-12-11 | 2015-12-11 | Online sampling system for traditional Chinese medicine production process and sampling device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510912462.5A CN105445052A (en) | 2015-12-11 | 2015-12-11 | Online sampling system for traditional Chinese medicine production process and sampling device |
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| CN105445052A true CN105445052A (en) | 2016-03-30 |
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| CN201510912462.5A Pending CN105445052A (en) | 2015-12-11 | 2015-12-11 | Online sampling system for traditional Chinese medicine production process and sampling device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111077107A (en) * | 2020-01-08 | 2020-04-28 | 山东金璋隆祥智能科技有限责任公司 | Online detection method for content of glycoside in stevioside extracting solution |
| CN111122251A (en) * | 2019-12-31 | 2020-05-08 | 深圳市华域环保科技有限公司 | Waste water discharge monitoring system in waste soil treatment process |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111122251A (en) * | 2019-12-31 | 2020-05-08 | 深圳市华域环保科技有限公司 | Waste water discharge monitoring system in waste soil treatment process |
| CN111077107A (en) * | 2020-01-08 | 2020-04-28 | 山东金璋隆祥智能科技有限责任公司 | Online detection method for content of glycoside in stevioside extracting solution |
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Application publication date: 20160330 |