CN105412560A

CN105412560A - Medicine for treating common cold and preparation method thereof

Info

Publication number: CN105412560A
Application number: CN201510876535.XA
Authority: CN
Inventors: 安耀苍
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-12-03
Filing date: 2015-12-03
Publication date: 2016-03-23

Abstract

The invention discloses a medicine for treating a common cold and a preparation method thereof. The medicine is mainly prepared from poria cocos, mangnolia officinalis, radix ophiopogonis, liquorice, ligusticum wallichii, cassia twigs, honeysuckle, pericarpium citri reticulatae, almond, pinellia ternate, radix bupleuri and mint according to a certain weight ratio. The medicine has the functions of warming the meridians, expelling the evils in muscles by means of diaphoresis, dispelling wind and dissipating heat, and repelling foulness and relieving internal heat or fever, becomes effective rapidly when used for treating a common cold, and is good in treatment effect.

Description

A kind of medicine for the treatment of cold and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of cold and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Cold is the common fever caused by exogenous pathogenic factors caused by ailment said due to cold or exposure invasion and attack human body.All can occur throughout the year.Especially be common with winter and spring.Clinical is main syndromes feature with headache, the cough of nasal obstruction, sneeze, watery nasal discharge, itching throat, fever with chills etc.The state of an illness has weight different, and the lighter is commonly called as cold, and severe one is called myxoidedema.Because current Western medicine effectively cannot treat cold, therefore there is great demand to the Chinese medicine that rapid, effective treatment is caught cold in people, up to now, also do not find about relevant report of the present invention.

Summary of the invention

The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment cold, thus completes the present invention.

Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment cold.

Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.

Medicine of the present invention selects Poria, Cortex Magnoliae Officinalis, Radix Ophiopogonis, Radix Glycyrrhizae, Rhizoma Chuanxiong, Ramulus Cinnamomi, Flos Lonicerae, Pericarpium Citri Reticulatae, Semen Armeniacae Amarum, the Rhizoma Pinelliae, Radix Bupleuri, Herba Menthae medicine to combine, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat cold.Wherein select Poria to be because its property slightly sweet flavor, flat, enter the heart, spleen, lung meridian, have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming, control dysuria edema distending pain, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.Select Cortex Magnoliae Officinalis to be because its nature and flavor toil, temperature, enter spleen, stomach, large intestine channel, have warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, dampness, the function of expectorant, control breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, cold-damp dysentery.Select be because its property sweet and slightly bitter taste Radix Ophiopogonis, cold, enter lung, stomach, heart channel, have nourishing YIN and moistening the lung, clear away heart-fire relieving restlessness, and the function of reinforcing stomach reg fluid controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, and clearly yearningly, calentura Tianjin is hindered, dry mouth and throat, constipation; Select Radix Glycyrrhizae to be because its nature and flavor are sweet, flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, processs use, controls weakness of the spleen and stomach, lack of appetite, stomachache loose stool, and overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus ， Jing Epilepsy; Raw use, controls laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis; Select Rhizoma Chuanxiong to be that temperature, enters liver, gallbladder meridian, have activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, the function of promoting blood circulation and stopping pain, control air-cooled headache and revolve dizzy because its nature and flavor are pungent, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores; Select Ramulus Cinnamomi to be because its property acrid-sweet flavor, temperature, enter bladder, the heart, lung meridian, have diaphoresis expelling pathogenic factors from muscles, the function of warming the meridian and promoting blood circulation, controls exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen; Flos Lonicerae is selected to be because its nature and flavor are sweet, cold, enter lung, stomach warp, have heat clearing away, the function of removing toxic substances, control epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula; Select Pericarpium Citri Reticulatae to be because its nature and flavor are bitter, pungent, temperature, return lung, spleen channel, have regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm, controls fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm; Select Semen Armeniacae Amarum to be because its nature and flavor are bitter, temperature, poisonous, enter lung, large intestine channel, have expelling phlegm for arresting cough, relieving asthma, the function of intestine moistening, controls exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation; Select the Rhizoma Pinelliae to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, stomach warp, have drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass, control damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm is had a headache, dizzy sleeplessness, outer subduing inflammation; Select Radix Bupleuri to be that cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, controls alternate attack of chill and fever, fullness in the chest and hypochondriac pain because its nature and flavor are bitter, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse; Select Herba Menthae to be because its nature and flavor are pungent, cool, enter lung, Liver Channel, have dispelling wind, heat radiation, ward off dirty, the function of removing toxic substances, controls affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.

Detailed description of the invention

The drug dose of the present invention's combination is also that inventor draws through groping in a large number to sum up, and the consumption of each grouping all has good therapeutic effect within the scope of following weight:

Poria 10-20g, Cortex Magnoliae Officinalis 10-20g, Radix Ophiopogonis 5-18g, Radix Glycyrrhizae 10-22g,

Rhizoma Chuanxiong 5-15g, Ramulus Cinnamomi 10-18g, Flos Lonicerae 10-20g, Pericarpium Citri Reticulatae 5-15g,

Semen Armeniacae Amarum 5-15g, Rhizoma Pinelliae 10-20g, Radix Bupleuri 10-22g, Herba Menthae 10-20g

Be preferably:

Poria 12g, Cortex Magnoliae Officinalis 15g, Radix Ophiopogonis 10g, Radix Glycyrrhizae 15g,

Rhizoma Chuanxiong 12g, Ramulus Cinnamomi 16g, Flos Lonicerae 15g, Pericarpium Citri Reticulatae 10g,

Semen Armeniacae Amarum 12g, Rhizoma Pinelliae 16g, Radix Bupleuri 15g, Herba Menthae 12g

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;

2, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;

3, Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;

4, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through section, dry;

5, Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;

6, Ramulus Cinnamomi: slightly soak with water, pulls out, and moistening, to thoroughly, is cut into slices, dried, sieve anti-dandruff;

7, Flos Lonicerae: sieve removes silt, picks clean impurity;

8, Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;

9, Semen Armeniacae Amarum: pick clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, in leaching cold water, sloughs seed coat, dries, and winnows with a dustpan clean;

10, the Rhizoma Pinelliae: pick decontamination, sieve dedust bits;

11, Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry immediately;

12, Herba Menthae: pick clean impurity, removing undesirable root, cutting, dries, then with leaf and even.

Two, prepare

1, described Poria, Cortex Magnoliae Officinalis, Radix Ophiopogonis, Radix Glycyrrhizae, Rhizoma Chuanxiong, Ramulus Cinnamomi, Flos Lonicerae, Pericarpium Citri Reticulatae, Semen Armeniacae Amarum, the Rhizoma Pinelliae, Radix Bupleuri, Herba Menthae are decocted with water twice, add water 6 times amount for the first time, intense fire decocts boiling 10 minutes, then uses slow fire boiling 25 minutes, filter first time decoction liquor.

2, add water the medicinal residues after first time filtration 4 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters and to obtain second time decoction liquor.

3, merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into two doses to take.

Medicine of the present invention has warming the meridian and promoting blood circulation, diaphoresis expelling pathogenic factors from muscles, wind-dispelling heat-dissipating, wards off the function of dirty removing toxic substances, is used for the treatment of cold instant effect, good effect.Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.

The animal toxicity test of [test example 1] medicine of the present invention

Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1, physical data

Accept out-patient's totally 43 examples for medical treatment.

2, diagnostic criteria

The inflammation of catching cold generally with a certain position of upper respiratory tract or whole upper respiratory tract, comprises nose, nasal sinuses, larynx, pharynx, and often involves trachea and bronchus.All can occur throughout the year.General Symptoms is light, does not usually generate heat, slight fear of cold, heating, headache.Nasal obstruction, during secondary bacterial infection, can there is bonum et laudabile pus sexual secretion in watery nasal discharge (clear water sample).Pharyngalgia, dry pharynx, slightly coughs, a small amount of white expectorant.

3, Therapeutic Method

Select above-mentioned medicament, take to patient, every day two doses, each potion, takes medicine 3 days continuously sooner or later.

4, efficacy assessment standard

Effective: the recovery from illness of cold symptom, recover normal.

Take a turn for the better: cold disease states alleviates, and symptom improves, and the state of an illness progressively takes a turn for the better.

Invalid: not reach improvement standard person.

5, therapeutic outcome (seeing the following form):

In above-mentioned treatment, by Drug therapy cold patient 43 example of the present invention, effective 39 examples of result, obvious effective rate is 90.7%, and take a turn for the better 2 examples, and improvement rate is 4.65%, and invalid 2 examples, total effective rate is 95.35%.

Claims

1. treat a medicine for cold, it is characterized in that: it is made up of the crude drug in following weight range:

Semen Armeniacae Amarum 5-15g, Rhizoma Pinelliae 10-20g, Radix Bupleuri 10-22g, Herba Menthae 10-20g.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Semen Armeniacae Amarum 12g, Rhizoma Pinelliae 16g, Radix Bupleuri 15g, Herba Menthae 12g.

3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:

(1) get the raw materials ready

(1) Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;

(2) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;

(3) Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;

(4) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through section, dry;

(5) Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;

(6) Ramulus Cinnamomi: slightly soak with water, pulls out, and moistening, to thoroughly, is cut into slices, dried, sieve anti-dandruff;

(7) Flos Lonicerae: sieve removes silt, picks clean impurity;

(8) Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;

(9) Semen Armeniacae Amarum: pick clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, in leaching cold water, sloughs seed coat, dries, and winnows with a dustpan clean;

(10) Rhizoma Pinelliae: pick decontamination, sieve dedust bits;

(11) Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry immediately;

(12) Herba Menthae: pick clean impurity, removing undesirable root, cutting, dries, then with leaf and even;

(2) prepare

(1) described Poria, Cortex Magnoliae Officinalis, Radix Ophiopogonis, Radix Glycyrrhizae, Rhizoma Chuanxiong, Ramulus Cinnamomi, Flos Lonicerae, Pericarpium Citri Reticulatae, Semen Armeniacae Amarum, the Rhizoma Pinelliae, Radix Bupleuri, Herba Menthae are decocted with water twice, add water 6 times amount for the first time, intense fire decocts boiling 10 minutes, then uses slow fire boiling 25 minutes, filter first time decoction liquor;

(2) add water the medicinal residues after first time filtration 4 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters and to obtain second time decoction liquor;

(3) merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into two doses to take.