CN105412509A - Traditional Chinese medicine plaster for treating scapulohumeral periarthritis and preparation method thereof - Google Patents

Traditional Chinese medicine plaster for treating scapulohumeral periarthritis and preparation method thereof Download PDF

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CN105412509A
CN105412509A CN201510970950.1A CN201510970950A CN105412509A CN 105412509 A CN105412509 A CN 105412509A CN 201510970950 A CN201510970950 A CN 201510970950A CN 105412509 A CN105412509 A CN 105412509A
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parts
radix
plaster
scapulohumeral periarthritis
aloe
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袁国防
张丽丽
李莹
施文斌
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Qingdao Haizhixing Biotechnology Co Ltd
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Qingdao Haizhixing Biotechnology Co Ltd
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Abstract

The invention discloses a traditional Chinese medicine plaster for treating scapulohumeral periarthritis and a preparation method thereof. The traditional Chinese medicine plaster is prepared from, by weight, 20-25 parts of radix zanthoxyli, 6-8 parts of roots of giantleaf ardisia rhizome, 3-5 parts of radix psammosilenes, 6-8 parts of anisodus acutangulus, 4-7 parts of pini lignum nodi, 5-8 parts of roots of common lamiophlomis, 4-6 parts of rhzizoma drynariae, 5-8 parts of phyllanthus reticulata, 4-6 parts of philippine flemingia roots, 5-8 parts of Chinese fevervine herb, 6-9 parts of wooly datchmanspipe herb, 10-14 parts of herba portulacae, 8-10 parts of aloe, 5-9 parts of blueberries, 4-7 parts of prepared liquorice roots, 12-17 parts of laurocapram, 7-10 parts of squalane, 8-13 parts of propolis, 7-10 parts of chamomile essential oil and 1-3 parts of dicyan isobutyl acrylate. A pure traditional Chinese medicine preparation is adopted and directly acted on an affected part for a long time, uncomfortable symptoms such as swelling and pain of the affected part are relieved rapidly, both symptoms and root causes of the scapulohumeral periarthritis are treated, the formula is mild, safe and free of side effects, relapse is not prone to occurrence after healing, drug resistance is not produced, and the curative effect is significant.

Description

Chinese medicinal plaster of a kind of cure scapulohumeral periarthritis and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of Chinese medicinal plaster and preparation method thereof of cure scapulohumeral periarthritis.
Background technology
Scapulohumeral periarthritis refers to and produces pain gradually with shoulder, night is very, increase the weight of gradually, shoulder mobility function limitation and day by day increasing the weight of, cause necessarily to a certain degree after alleviate gradually, until be finally restored to the capsula articularis humeri of main manifestations and the chronic specific inflammatory of surrounding ligaments, tendon and synovial bursa thereof completely.Women's sickness rate, higher than male, is more common in physical labourer.The common disease that scapulohumeral periarthritis is is cardinal symptom with shoulder arthralgia and inconvenient activity.Primary disease send out the age at about 50 years old well, women's sickness rate, a little more than male, is more common in physical labourer.As can not get effective treatment, likely having a strong impact on the functional activity of shoulder joint, hindering daily life.The early stage shoulder joint of primary disease is paroxysmal pain, often brings out because of Changes in weather and fatigue, develops into rest pain later gradually, and increase the weight of gradually, light night in daytime is heavy, lies awake all night, can not lie on one's side to Ipsilateral, shoulder joint to the active of all directions and passive activity all limited.When shoulder is subject to tractive, can causes and have an intense pain.Shoulder joint can have extensive tenderness, and to cervical region and ancon radiation, also can occur the atrophy of triangular muscle in various degree.Scapulohumeral periarthritis, as chronic disease, for a long time, affects the orthobiosis of patient, work, bring a lot of trouble, some patient seeks medical advice everywhere, recurrent exerbation, agonizing, even psychological cloud, thinks that scapulohumeral periarthritis is incurable disease, and adopting tcm therapy to treat this disease is the Therapeutic Method that relatively safety is desirable, the traditional Chinese medical science is thought, scapulohumeral periarthritis is the chronic disease caused by wind-cold damp pathogen invasion and attack shoulder muscle arteries and veins.Endogenous cause of ill battalion defends weakness, and muscles and bones is failed, and exopathogen is taken advantage of a weak point, and injures shoulder muscle arteries and veins, causes QI and blood obstructed and pain.
Summary of the invention
The object of the invention is that providing a kind of treats Chinese medicinal plaster of tenosynovitis scapulohumeral periarthritis and preparation method thereof, adopt pure Chinese medicinal preparation, direct long duration of action is in affected part, the malaise symptoms such as swell and ache in rapid recovery affected part, this disease for the treatment of both the principal and secondary aspects of a disease, the gentle safety of formula has no side effect, and not easily recurs more, and can not drug resistance be produced, evident in efficacy.
A kind of Chinese medicinal plaster of cure scapulohumeral periarthritis, crude drug composition and the parts by weight of making described plaster are: Radix Zanthoxyli 20-25 part, Rhizoma Ardisiae Gigantifoliae root 6-8 part, Radix Psammosilenes 3-5 part, Radix Anisodi Acutanguli 6-8 part, Pine Nodular Branch 4-7 part, Radix Lamiophlomidis Rotatae 5-8 part, Rhizoma Drynariae 4-6 part, snapper eye 5-8 part, Radix Flemingiae Philippinensis 4-6 part, fevervine 5-8 part, Herba Aristolochiae Mollissimae 6-9 part, Herba Portulacae 10-14 part, Aloe 8-10 part, blue berry 5-9 part, Radix Glycyrrhizae Preparata 4-7 part, laurocapram 12-17 part, squalane 7-10 part, propolis 8-13 part, chamomile essential oil 7-10 part, dicyano Isobutyl 2-propenoate 1-3 part.
Preferably, crude drug composition and the parts by weight of making described plaster are: Radix Zanthoxyli 20 parts, Rhizoma Ardisiae Gigantifoliae root 6 parts, Radix Psammosilenes 3 parts, Radix Anisodi Acutanguli 6 parts, Pine Nodular Branch 4 parts, Radix Lamiophlomidis Rotatae 5 parts, Rhizoma Drynariae 4 parts, snapper eye 5 parts, Radix Flemingiae Philippinensis 4 parts, fevervine 5 parts, Herba Aristolochiae Mollissimae 6 parts, Herba Portulacae 10 parts, Aloe 8 parts, blue berry 5 parts, Radix Glycyrrhizae Preparata 4 parts, laurocapram 12 parts, squalane 7 parts, propolis 8 parts, chamomile essential oil 7 parts, dicyano Isobutyl 2-propenoate 1 part.
Preferably, crude drug composition and the parts by weight of making described plaster are: Radix Zanthoxyli 25 parts, Rhizoma Ardisiae Gigantifoliae root 8 parts, Radix Psammosilenes 5 parts, Radix Anisodi Acutanguli 8 parts, Pine Nodular Branch 7 parts, Radix Lamiophlomidis Rotatae 8 parts, Rhizoma Drynariae 6 parts, snapper eye 8 parts, Radix Flemingiae Philippinensis 6 parts, fevervine 8 parts, Herba Aristolochiae Mollissimae 9 parts, Herba Portulacae 14 parts, Aloe 10 parts, blue berry 9 parts, Radix Glycyrrhizae Preparata 7 parts, laurocapram 17 parts, squalane 10 parts, propolis 13 parts, chamomile essential oil 10 parts, dicyano Isobutyl 2-propenoate 3 parts.
Preferably, crude drug composition and the parts by weight of making described plaster are: Radix Zanthoxyli 22 parts, Rhizoma Ardisiae Gigantifoliae root 7 parts, Radix Psammosilenes 4 parts, Radix Anisodi Acutanguli 7 parts, Pine Nodular Branch 6 parts, Radix Lamiophlomidis Rotatae 6 parts, Rhizoma Drynariae 5 parts, snapper eye 7 parts, Radix Flemingiae Philippinensis 5 parts, fevervine 6 parts, Herba Aristolochiae Mollissimae 7 parts, Herba Portulacae 12 parts, Aloe 9 parts, blue berry 7 parts, Radix Glycyrrhizae Preparata 6 parts, laurocapram 14 parts, squalane 8 parts, propolis 10 parts, chamomile essential oil 9 parts, dicyano Isobutyl 2-propenoate 2 parts.
The invention also discloses the preparation method of the Chinese medicinal plaster of described cure scapulohumeral periarthritis, comprise the following steps:
(1) Rhizoma Ardisiae Gigantifoliae root, Radix Psammosilenes, Radix Anisodi Acutanguli, Pine Nodular Branch, Radix Lamiophlomidis Rotatae, snapper eye, Radix Flemingiae Philippinensis, Herba Aristolochiae Mollissimae are crushed to 50 order Chinese medicine coarse powder;
(2) step (1) gained Chinese medicine coarse powder adds the water soaking 1 hour of gross mass multiple 4 times, slow fire boiling 2 hours, crosses 500 order drainage screens and obtain filtrate and dry in the air cool for subsequent use to room temperature after decocting;
(3) Radix Zanthoxyli, Rhizoma Drynariae, fevervine super micron mill are pulverized, and cross 1000 mesh sieves and obtain mixed-powder, for subsequent use;
(4) Herba Portulacae fresh goods, Aloe fresh goods, blueberry fresh fruit mixing are cleaned, add after the mixing of step (2) gained filtrate is squeezed the juice and leave standstill 2 hours, cross 200 order filter screen filtration, gained filtrate adds in low-temperature vacuum thickener, and cryoconcentration (less than 40 DEG C) to relative density is the thick paste of 1.30 ± 0.02 (30 DEG C);
(5) by after squalane, propolis heating and melting, continuous stirring, add laurocapram, chamomile essential oil and dicyano Isobutyl 2-propenoate, when temperature is down to 50 DEG C, add the thick paste that step (4) is obtained, mixing, then add the mixed-powder that step (3) is obtained, stirring and evenly mixing, make cream core, and be placed on sticker, obtain the Chinese medicinal plaster of described cure scapulohumeral periarthritis.
To achieve these goals, technical scheme provided by the invention is as follows:
The traditional Chinese medical science thinks that the morbidity of scapulohumeral periarthritis is mainly because of wind-cold damp pathogen invasion and attack shoulder muscle arteries and veins, QI and blood is caused to block, caused by passages through which vital energy circulates mistake is supported, the invention discloses a kind of external plaster that can directly act on affected part for a long time, this plaster is for the inherent cause of disease of this disease and external disease, and external preparation directly acts on affected part and easily causes skin sensitivity to affect the problem of skin health, take expelling wind and cold, relaxing muscles and tendons to promote blood circulation, reducing swelling and alleviating pain, the method of Shu Min granulation promoting, according to Chinese medical theory determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, raw material of Chinese medicine is screened by great many of experiments, refining agent method, each efficacy of drugs is made to produce synergism, thus reach the effect for the treatment of both the principal and secondary aspects of a disease.Specifically, in the crude drug chosen:
Radix Zanthoxyli: property is put down, bitter in the mouth, pungent, promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral, with controlling injury from falling down that qi depression to blood stasis causes, rheumatic arthralgia, stomachache, toothache, venom, the burning hot wound of external treatment soup;
Rhizoma Ardisiae Gigantifoliae root: bitter, micro-pungent, warm in nature, wind-damp dispelling, promoting blood circulation and stopping pain, removing toxic substances granulation promoting, main air pain of dampness syndrome, puerperal blood stasis, carbuncle ulcer, treating swelling and pain by traumatic injury;
Radix Psammosilenes: warm in nature, bitter in the mouth, pungent, expelling wind and removing dampness, eliminating stasis to stop pain, removing toxic substances and promoting subsidence of swelling, uses dispelling the wind and dampness pathogens arthralgia pain, stomachache with cool feeling, traumatic injury, traumatic hemorrhage; External treatment furuncle, snake bite and insect sting;
Radix Anisodi Acutanguli: warm in nature, bitter in the mouth, pungent, spasmolysis and analgesia, expelling wind and removing dampness, with treating for stomachache, gallbladder, kidney, intestinal colic, Fengshi Guanjie pain, lumbago and skelalgia, traumatic injury;
Pine Nodular Branch: warm in nature, bitter in the mouth, pungent, expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, with controlling anemofrigid-damp arthralgia, severe and migratory arthralgia pain, convulsion contraction is anxious, traumatic pain;
Radix Lamiophlomidis Rotatae: property is put down, sweet in the mouth, hardship, promoting blood circulation and hemostasis, wind-expelling pain-stopping, with controlling traumatic injury, traumatic hemorrhage, rheumatic arthralgia, grasserie;
Rhizoma Drynariae: warm in nature, bitter in the mouth, continues and hinders pain relieving, the kidney invigorating bone strengthening, with controlling lumbago due to renal deficiency, toothache, tinnitus, chronic diarrhea, traumatic injury, alopecia areata, clavus etc.;
Snapper eye: property is put down, and taste is micro-puckery, expelling wind and activating blood circulation, dissipating blood stasis for subsidence of swelling, by dispelling the wind and dampness pathogens arthralgia, traumatic injury;
Radix Flemingiae Philippinensis: property is put down, sweet in the mouth, micro-puckery, expelling wind and removing dampness, bone and muscle strengthening, and promoting blood circulation and detoxication, cures mainly rheumatic arthralgia, lumbar muscle strain, and extremity flaccidity is soft, traumatic injury, laryngopharynx swelling and pain;
Fevervine: property is put down, sweet in the mouth, acid, expelling wind and activating blood circulation, analgesic antidotal, dyspepsia and intestinal stasis relieving, dehumidifying detumescence, by dispelling the wind and dampness pathogens pain, diarrhoea dysentery, epigastric pain, deficiency of vital energy edema, dizzy lack of appetite, hepatosplenomegaly, scrofula, acute appendicitis, innominate toxic swelling, traumatic injury etc.;
Herba Aristolochiae Mollissimae: property is put down, acrid in the mouth, hardship, and dispelling wind and removing obstruction in the collateral, promoting the circulation of QI to relieve pain, with dispelling the wind and dampness pathogens arthralgia pain, numb limbs and tense tendons, muscles and bones contracture, traumatic injury pain, stomachache, toothache, colic etc.;
Herba Portulacae: cold in nature, sweet in the mouth acid, enter the heart, liver, spleen, large intestine channel, have that removing dampness is antipruritic, clearing heat for detumescence, heat-clearing and toxic substances removing, diuretic dries, loose blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, the effect of hemostasis removing heat from blood.Herba Portulacae is to dysentery bacterium, Bacillus typhi and escherichia coli have stronger inhibitory action, can be used for the auxiliary treatment of various inflammation, have the title of " natural antibiotics ", Herba Portulacae is also rich in vitamin C simultaneously, vitamin C has good antioxidation can whitening nourishes rough skin, modern medicine finds, Herba Portulacae has higher nutritive value and medical value, except the protein containing routine, outside the nutrient such as vitamin and mineral, Herba Portulacae is also containing unique bioactive ingredients, the activity of Human Epithelial Cells can be strengthened, help lend some impetus to ulcer and healing,
Aloe: pathogenic fire purging, removing toxic substances, blood stasis dispelling, parasite killing, argument is red, constipation, nebulousurine, hematuria, pediatric epilepsy scared, infantile malnutrition, burn and scald, women's amenorrhea, hemorrhoid, scabies, carbuncle furuncle and phyma poison, traumatic injury, mucus (mucin in Aloe, be exactly protein), for nucleus with polysaccharides such as arboranABaloemannanaloetin, mucus class material is the important component preventing cell senescence and treatment chronic allergic, mucoitin is present in the place such as muscle and gastrointestinal mucosa of human body, allow and organize high resilience, if liquid element is not enough, muscle and mucosa will lose elasticity and stiff aging, Aloin A, wound hormone and polysaccharide peptide manna (Ke-2) etc. have viral infection resisting, promote the effect that wound healing restores, there is anti-inflammation and sterilization, heat absorption detumescence, softening skin, keep the function of cell viability, curdlan is combined with 1-decene-1 and is also had healing wounds activity,
Chamomile essential oil: acne, allergy, eczema, burn and scald can be improved; can say it is to one of best hydrosol of skin; there is antiinflammatory and pacify characteristic; for responsive and acne vulgaris skin; fabulous to dryness, sensitive skin, there is good effect to treatment pimples, herpes, eczema, tinea, microvascular, can be used for the eye skin protecting face the most responsive; for treatment acne vulgaris and red seal Be very effective, increase skin resistance.
Blue berry: containing abundant nutritional labeling in fruit, have prevent that cranial nerve is aging, vision protection, heart tonifying, anticancer, vessel softening, the function such as enhancing human organism immunity, nutritional labeling is high, it is a kind of strong antioxidant that blue berry is rich in anthocyanidin glycoside, it can protect human body from the damage of free radical, anthocyanidin glycoside can also strengthen blood vessel elasticity, improve the smoothness of blood circulation and enhancement skin, inflammation-inhibiting and allergy, vitamin C in blue berry is one of antioxidant vitamins, can effective scavenging free radicals, prevent skin aging;
Radix Glycyrrhizae Preparata: containing number of chemical compositions such as glycyrrhizin, enoxolone, Angelica Polysaccharide, there is antiinflammatory and anti-allergy action, scalable body's immunity, antitumor and analgesic effect, therefore the primary efficacy of Radix Glycyrrhizae Preparata is and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.
In all medicines, Radix Zanthoxyli is monarch drug, plays the effect of expelling wind and cold, relaxing muscles and tendons to promote blood circulation, reducing swelling and alleviating pain, for this disease of cause of disease treatment for diseases.Rhizoma Ardisiae Gigantifoliae root, Radix Psammosilenes, Radix Anisodi Acutanguli, Pine Nodular Branch, Radix Lamiophlomidis Rotatae, Rhizoma Drynariae, snapper eye, Radix Flemingiae Philippinensis, fevervine, Herba Aristolochiae Mollissimae are ministerial drug, gain monarch drug drug effect, wherein, Rhizoma Ardisiae Gigantifoliae root, Radix Psammosilenes, Radix Anisodi Acutanguli, Pine Nodular Branch, Radix Lamiophlomidis Rotatae, snapper eye, Radix Flemingiae Philippinensis, fevervine, Herba Aristolochiae Mollissimae can remove the effect of expelling wind and cold by gain monarch drug, directly act on affected part, effectively dispel affected part wind-cold damp pathogen, the effect of Rhizoma Ardisiae Gigantifoliae root, Radix Lamiophlomidis Rotatae, snapper eye, Radix Flemingiae Philippinensis, all right gain monarch drug relaxing muscles and tendons to promote blood circulation of fevervine, the cause of disease of supporting is lost in the retardance of effective remissive treatment affected part QI and blood, passages through which vital energy circulates, Rhizoma Ardisiae Gigantifoliae root, Radix Psammosilenes, Radix Anisodi Acutanguli, Pine Nodular Branch, Radix Lamiophlomidis Rotatae, Rhizoma Drynariae, fevervine, Herba Aristolochiae Mollissimae have the effect of reducing swelling and alleviating pain, can swell and ache in rapid recovery affected part, eliminate patient suffering, in ministerial drug, Radix Anisodi Acutanguli and Oleum Terebinthinae all can actual gain monarch drug drug effects, but the alkaloid component contained by Radix Anisodi Acutanguli, and the Camphor tree alkene contained by Oleum Terebinthinae, cinene all easily causes skin allergy symptom, and life-time service topical agent is also easy damages skin, make dull-looking skin coarse, in order to alleviate these side effect, the present invention is with Herba Portulacae, Aloe, chamomile essential oil, blue berry is assistant, play the effect of Shu Min granulation promoting, available protecting nourishes illing skin, prevention skin allergy, wherein, it is a kind of strong antioxidant that blue berry is rich in anthocyanidin glycoside, it can protect human body from the damage of free radical, anthocyanidin glycoside can also strengthen blood vessel elasticity, improve the smoothness of blood circulation and enhancement skin, inflammation-inhibiting and allergy, vitamin C in blue berry is one of antioxidant vitamins, can effective scavenging free radicals, prevent skin aging, Herba Portulacae, Aloe also has good analgesic effect, can the effect of reducing swelling and alleviating pain of gain monarch drug ministerial drug.Radix Glycyrrhizae Preparata, for making, plays harmonizing yingfen and weifen, the effect of warming spleen and stomach for dispelling cold.Plaster of the present invention is pure Chinese medicinal preparation, selected medical material compatibility is suitable, and adopt modern advanced medical pharmaceutical technology to make, affected part can be directly acted on for a long time, there is treating both the principal and secondary aspects of a disease rapid-action, can effectively reduction of patient be painful fast, not easily recur more, the remarkable advantage of safe without toxic side effect, is adapted to the treatment to scapulohumeral periarthritis.
Beneficial effect of the present invention is: provide plaster of a kind of cure scapulohumeral periarthritis and preparation method thereof, adopt pure Chinese medicinal preparation, affected part can be directly acted on for a long time, the malaise symptoms such as swell and ache in rapid recovery affected part, this disease for the treatment of both the principal and secondary aspects of a disease, the gentle safety of formula has no side effect, and not easily recurs more, and can not drug resistance be produced, evident in efficacy.This plaster is the chronic disease caused by wind-cold damp pathogen invasion and attack shoulder muscle arteries and veins for scapulohumeral periarthritis, endogenous cause of ill battalion defends weakness, muscles and bones is failed, exopathogen is taken advantage of a weak point, injure shoulder muscle arteries and veins, cause QI and blood obstructed and the cause of disease disease of pain, take expelling wind and cold, the method of relaxing muscles and tendons to promote blood circulation treats this disease, can effectively reducing swelling and alleviating pain reduction of patient be painful, simultaneously, skin allergy is caused in order to prevent the allergen in raw material, make dull-looking skin coarse, the present invention is with Herba Portulacae, Aloe, chamomile essential oil, blue berry is assistant, play the effect of Shu Min granulation promoting, available protecting nourishes illing skin, prevention skin allergy, wherein, it is a kind of strong antioxidant that blue berry is rich in anthocyanidin glycoside, it can protect human body from the damage of free radical, anthocyanidin glycoside can also strengthen blood vessel elasticity, improve the smoothness of blood circulation and enhancement skin, inflammation-inhibiting and allergy, vitamin C in blue berry is one of antioxidant vitamins, can effective scavenging free radicals, prevent skin aging, compatibility of drugs is proper, all medicines are nursed one's health mutually, body is had no adverse effects, apply safer.
Detailed description of the invention
According to following embodiment, the present invention may be better understood.But those skilled in the art will readily understand, concrete material proportion, process conditions and result thereof described by embodiment only should can not limit the present invention described in detail in claims yet for illustration of the present invention.
Embodiment 1
A Chinese medicinal plaster for cure scapulohumeral periarthritis, crude drug composition and the parts by weight of making described plaster are: Radix Zanthoxyli 20 parts, Rhizoma Ardisiae Gigantifoliae root 6 parts, Radix Psammosilenes 3 parts, Radix Anisodi Acutanguli 6 parts, Pine Nodular Branch 4 parts, Radix Lamiophlomidis Rotatae 5 parts, Rhizoma Drynariae 4 parts, snapper eye 5 parts, Radix Flemingiae Philippinensis 4 parts, fevervine 5 parts, Herba Aristolochiae Mollissimae 6 parts, Herba Portulacae 10 parts, Aloe 8 parts, blue berry 5 parts, Radix Glycyrrhizae Preparata 4 parts, laurocapram 12 parts, squalane 7 parts, propolis 8 parts, chamomile essential oil 7 parts, dicyano Isobutyl 2-propenoate 1 part.
The preparation method of described plaster, comprises the following steps:
(1) Rhizoma Ardisiae Gigantifoliae root, Radix Psammosilenes, Radix Anisodi Acutanguli, Pine Nodular Branch, Radix Lamiophlomidis Rotatae, snapper eye, Radix Flemingiae Philippinensis, Herba Aristolochiae Mollissimae are crushed to 50 order Chinese medicine coarse powder;
(2) step (1) gained Chinese medicine coarse powder adds the water soaking 1 hour of gross mass multiple 4 times, slow fire boiling 2 hours, crosses 500 order drainage screens and obtain filtrate and dry in the air cool for subsequent use to room temperature after decocting;
(3) Radix Zanthoxyli, Rhizoma Drynariae, fevervine super micron mill are pulverized, and cross 1000 mesh sieves and obtain mixed-powder, for subsequent use;
(4) Herba Portulacae fresh goods, Aloe fresh goods, blueberry fresh fruit mixing are cleaned, add after the mixing of step (2) gained filtrate is squeezed the juice and leave standstill 2 hours, cross 200 order filter screen filtration, gained filtrate adds in low-temperature vacuum thickener, and cryoconcentration (less than 40 DEG C) to relative density is the thick paste of 1.30 ± 0.02 (30 DEG C);
(5) by after squalane, propolis heating and melting, continuous stirring, add laurocapram, chamomile essential oil and dicyano Isobutyl 2-propenoate, when temperature is down to 50 DEG C, add the thick paste that step (4) is obtained, mixing, then add the mixed-powder that step (3) is obtained, stirring and evenly mixing, make cream core, and be placed on sticker, obtain the Chinese medicinal plaster of described cure scapulohumeral periarthritis.
Using method: clean affected part skin, keep dry, then the plaster of the present embodiment is affixed on affected part, and press gently with palm, 8-12 as a child tore, after 8 hours, again paste portion, and operation is with first time.
Embodiment 2
A Chinese medicinal plaster for cure scapulohumeral periarthritis, crude drug composition and the parts by weight of making described plaster are: Radix Zanthoxyli 25 parts, Rhizoma Ardisiae Gigantifoliae root 8 parts, Radix Psammosilenes 5 parts, Radix Anisodi Acutanguli 8 parts, Pine Nodular Branch 7 parts, Radix Lamiophlomidis Rotatae 8 parts, Rhizoma Drynariae 6 parts, snapper eye 8 parts, Radix Flemingiae Philippinensis 6 parts, fevervine 8 parts, Herba Aristolochiae Mollissimae 9 parts, Herba Portulacae 14 parts, Aloe 10 parts, blue berry 9 parts, Radix Glycyrrhizae Preparata 7 parts, laurocapram 17 parts, squalane 10 parts, propolis 13 parts, chamomile essential oil 10 parts, dicyano Isobutyl 2-propenoate 3 parts.
The preparation method of the plaster of embodiment 2 is identical with embodiment 1 with using method.
Embodiment 3
A Chinese medicinal plaster for cure scapulohumeral periarthritis, crude drug composition and the parts by weight of making described plaster are: Radix Zanthoxyli 22 parts, Rhizoma Ardisiae Gigantifoliae root 7 parts, Radix Psammosilenes 4 parts, Radix Anisodi Acutanguli 7 parts, Pine Nodular Branch 6 parts, Radix Lamiophlomidis Rotatae 6 parts, Rhizoma Drynariae 5 parts, snapper eye 7 parts, Radix Flemingiae Philippinensis 5 parts, fevervine 6 parts, Herba Aristolochiae Mollissimae 7 parts, Herba Portulacae 12 parts, Aloe 9 parts, blue berry 7 parts, Radix Glycyrrhizae Preparata 6 parts, laurocapram 14 parts, squalane 8 parts, propolis 10 parts, chamomile essential oil 9 parts, dicyano Isobutyl 2-propenoate 2 parts.
The preparation method of the plaster of embodiment 3 is identical with embodiment 1 with using method.
Embodiment 4 hypersensitive test
Get healthy albino guinea-pig 18, body weight 250-300g, male and female dual-purpose, reject both sides dorsal body setae before test, every side 3 × 3cm, is divided into test group, blank group and positive controls positive controls with 2 at random, 4-dinitrochlorobenzene, sensitization 1% concentration, excites and uses 0.1% concentration; The test group plaster cream core of the embodiment of the present invention 3.The plaster cream core getting the embodiment of the present invention 3 is applied to unhairing district, back, the next day 1 time, totally 3 times.In latter 14 days of last contact, smear this plaster cream core at back the same area, at once observe after removing medicine after 6h, and in 24,48,72h observes with or without anaphylaxis.Blank group and positive controls excite by same method and contact and observe.Result of the test: namely positive controls animal skin occurs localized erythema and slight edema in sensitization after 1 hour, within 24 hours, symptoms of allergic increases the weight of, sensitization rate is 100%, and any symptoms of allergic does not all appear in test group and blank treated animal skin, and sensitization rate is 0%.Experimental result shows that plaster cream core formula gentleness of the present invention is non-stimulated.
Embodiment 5 clinical trial:
Random selecting 300 scapulohumeral periarthritis patients carry out clinical trial, patient is divided into 3 groups at random, plaster respectively in embodiment 1 to 3 on probation treats this disease, using method is: clean affected part skin, keeps dry, then the plaster of the present embodiment is affixed on affected part, and press gently with palm, 8-12 as a child tore, after 8 hours, again paste portion, and operation is with first time.Within 10th, be a course for the treatment of, investigate the curative effect of plaster of the present invention, the evaluation criterion of curative effect is:
Cure: shoulder joint function recovers normal, and pain disappears, around without tenderness and sensitive spot.
Effective: the energy-conservation abduction of shoulder joint, after stretch 70 °, pain substantially disappears or obviously alleviates, without obvious pressure pain point.
Effective: the energy-conservation abduction of shoulder joint, after stretch 50 °, shoulder can touch pressure pain point.
Invalid: before and after treatment, the state of an illness is unchanged.
Recurrence: be significantly improved after treatment, but repeat symptom again after drug withdrawal.
Statistical result is as follows:
Embodiment 1 Embodiment 2 Embodiment 3
Cure 61 68 73
Effective 35 22 21
Effectively 2 9 6
Invalid 2 1 0
Effective percentage (%) 98 99 100
Relapse rate (%) 0 0 0
All patients during medication all without bad reflection, experimental result shows, the effective percentage of plaster of the present invention reaches more than 98%, energy rapid recovery patients symptomatic, evident in efficacy, can safe and effective treatment tenosynovitis, all without skin allergy symptom during patient medication, without recurrence after curing, it is desirable medicine.
Clinical exemplary embodiments:
1. Xu so-and-so, female, 55 years old, right shoulder pain 3 months, without obvious inducement, right shoulder pain occur and increase the weight of movable extremely limited gradually, the right hand can not be combed one's hair, can not go up act, after revolve, abduction, touching then severe pain unbearably, uses the plaster of the embodiment of the present invention 3 to treat a course for the treatment of, and shoulder joint function recovers normal, pain disappears, around without tenderness and sensitive spot, patient fully recovers, and more later six months is without recurrence.
2. Zhang, man, 48 years old, bilateral shoulder pain, night more so, limitation of activity, can not go up act, after revolve, abduction, pressing shoulder has an intense pain, and uses the plaster of the embodiment of the present invention 1 to treat a course for the treatment of, the energy-conservation abduction of shoulder joint, after stretch 70 °, pain disappears substantially, without obvious pressure pain point, continue a course for the treatment of of use, shoulder joint function recovers normal, and pain disappears, around without tenderness and sensitive spot, patient fully recovers, and more later six months is without recurrence.
3. Zhao so-and-so, female, 45 years old, bilateral shoulder pain, limitation of activity, can not go up act, after revolve, abduction, the right hand can not be combed one's hair, pressing shoulder has an intense pain, and uses the plaster of the embodiment of the present invention 2 to treat a course for the treatment of, and shoulder joint function recovers normal, pain disappears, around without tenderness and sensitive spot, patient fully recovers, and more later six months is without recurrence.
Above embodiment is only for illustrating technical conceive of the present invention and feature; its object is to allow person skilled in the art understand content of the present invention and to be implemented; can not limit the scope of the invention with this; all equivalences done according to spirit of the present invention change or modify, and all should be encompassed in protection scope of the present invention.

Claims (5)

1. the Chinese medicinal plaster of a cure scapulohumeral periarthritis, it is characterized in that: crude drug composition and the parts by weight of making described plaster are: Radix Zanthoxyli 20-25 part, Rhizoma Ardisiae Gigantifoliae root 6-8 part, Radix Psammosilenes 3-5 part, Radix Anisodi Acutanguli 6-8 part, Pine Nodular Branch 4-7 part, Radix Lamiophlomidis Rotatae 5-8 part, Rhizoma Drynariae 4-6 part, snapper eye 5-8 part, Radix Flemingiae Philippinensis 4-6 part, fevervine 5-8 part, Herba Aristolochiae Mollissimae 6-9 part, Herba Portulacae 10-14 part, Aloe 8-10 part, blue berry 5-9 part, Radix Glycyrrhizae Preparata 4-7 part, laurocapram 12-17 part, squalane 7-10 part, propolis 8-13 part, chamomile essential oil 7-10 part, dicyano Isobutyl 2-propenoate 1-3 part.
2. the Chinese medicinal plaster of a kind of cure scapulohumeral periarthritis as claimed in claim 1, is characterized in that: crude drug composition and the parts by weight of making described plaster are: Radix Zanthoxyli 20 parts, Rhizoma Ardisiae Gigantifoliae root 6 parts, Radix Psammosilenes 3 parts, Radix Anisodi Acutanguli 6 parts, Pine Nodular Branch 4 parts, Radix Lamiophlomidis Rotatae 5 parts, Rhizoma Drynariae 4 parts, snapper eye 5 parts, Radix Flemingiae Philippinensis 4 parts, fevervine 5 parts, Herba Aristolochiae Mollissimae 6 parts, Herba Portulacae 10 parts, Aloe 8 parts, blue berry 5 parts, Radix Glycyrrhizae Preparata 4 parts, laurocapram 12 parts, squalane 7 parts, propolis 8 parts, chamomile essential oil 7 parts, dicyano Isobutyl 2-propenoate 1 part.
3. the Chinese medicinal plaster of a kind of cure scapulohumeral periarthritis as claimed in claim 1, is characterized in that: crude drug composition and the parts by weight of making described plaster are: Radix Zanthoxyli 25 parts, Rhizoma Ardisiae Gigantifoliae root 8 parts, Radix Psammosilenes 5 parts, Radix Anisodi Acutanguli 8 parts, Pine Nodular Branch 7 parts, Radix Lamiophlomidis Rotatae 8 parts, Rhizoma Drynariae 6 parts, snapper eye 8 parts, Radix Flemingiae Philippinensis 6 parts, fevervine 8 parts, Herba Aristolochiae Mollissimae 9 parts, Herba Portulacae 14 parts, Aloe 10 parts, blue berry 9 parts, Radix Glycyrrhizae Preparata 7 parts, laurocapram 17 parts, squalane 10 parts, propolis 13 parts, chamomile essential oil 10 parts, dicyano Isobutyl 2-propenoate 3 parts.
4. the Chinese medicinal plaster of a kind of cure scapulohumeral periarthritis as claimed in claim 1, is characterized in that: crude drug composition and the parts by weight of making described plaster are: Radix Zanthoxyli 22 parts, Rhizoma Ardisiae Gigantifoliae root 7 parts, Radix Psammosilenes 4 parts, Radix Anisodi Acutanguli 7 parts, Pine Nodular Branch 6 parts, Radix Lamiophlomidis Rotatae 6 parts, Rhizoma Drynariae 5 parts, snapper eye 7 parts, Radix Flemingiae Philippinensis 5 parts, fevervine 6 parts, Herba Aristolochiae Mollissimae 7 parts, Herba Portulacae 12 parts, Aloe 9 parts, blue berry 7 parts, Radix Glycyrrhizae Preparata 6 parts, laurocapram 14 parts, squalane 8 parts, propolis 10 parts, chamomile essential oil 9 parts, dicyano Isobutyl 2-propenoate 2 parts.
5. the preparation method of the Chinese medicinal plaster of any one cure scapulohumeral periarthritis as described in Claims 1-4, is characterized in that: comprise the following steps:
(1) Rhizoma Ardisiae Gigantifoliae root, Radix Psammosilenes, Radix Anisodi Acutanguli, Pine Nodular Branch, Radix Lamiophlomidis Rotatae, snapper eye, Radix Flemingiae Philippinensis, Herba Aristolochiae Mollissimae are crushed to 50 order Chinese medicine coarse powder;
(2) step (1) gained Chinese medicine coarse powder adds the water soaking 1 hour of gross mass multiple 4 times, slow fire boiling 2 hours, crosses 500 order drainage screens and obtain filtrate and dry in the air cool for subsequent use to room temperature after decocting;
(3) Radix Zanthoxyli, Rhizoma Drynariae, fevervine super micron mill are pulverized, and cross 1000 mesh sieves and obtain mixed-powder, for subsequent use;
(4) Herba Portulacae fresh goods, Aloe fresh goods, blueberry fresh fruit mixing are cleaned, add after the mixing of step (2) gained filtrate is squeezed the juice and leave standstill 2 hours, cross 200 order filter screen filtration, gained filtrate adds in low-temperature vacuum thickener, and cryoconcentration (less than 40 DEG C) to relative density is the thick paste of 1.30 ± 0.02 (30 DEG C);
(5) by after squalane, propolis heating and melting, continuous stirring, add laurocapram, chamomile essential oil and dicyano Isobutyl 2-propenoate, when temperature is down to 50 DEG C, add the thick paste that step (4) is obtained, mixing, then add the mixed-powder that step (3) is obtained, stirring and evenly mixing, make cream core, and be placed on sticker, obtain the Chinese medicinal plaster of described cure scapulohumeral periarthritis.
CN201510970950.1A 2015-12-22 2015-12-22 Traditional Chinese medicine plaster for treating scapulohumeral periarthritis and preparation method thereof Withdrawn CN105412509A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104524103A (en) * 2014-12-17 2015-04-22 芦明晓 External traditional Chinese medicine for diminishing inflammation, promoting blood circulation and removing meridian obstruction
CN104888147A (en) * 2015-06-30 2015-09-09 青岛海之星生物科技有限公司 Traditional Chinese medicine ointment for shoulder periarthritis and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104524103A (en) * 2014-12-17 2015-04-22 芦明晓 External traditional Chinese medicine for diminishing inflammation, promoting blood circulation and removing meridian obstruction
CN104888147A (en) * 2015-06-30 2015-09-09 青岛海之星生物科技有限公司 Traditional Chinese medicine ointment for shoulder periarthritis and preparation method thereof

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Application publication date: 20160323