CN105412472A - 一种治疗美容养颜、强身健体、延年益寿的中药组合物 - Google Patents

一种治疗美容养颜、强身健体、延年益寿的中药组合物 Download PDF

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CN105412472A
CN105412472A CN201510856100.9A CN201510856100A CN105412472A CN 105412472 A CN105412472 A CN 105412472A CN 201510856100 A CN201510856100 A CN 201510856100A CN 105412472 A CN105412472 A CN 105412472A
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孙西义
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Abstract

本发明涉及一种治疗美容养颜、强身健体、延年益寿的中药组合物,它包含人参、玛咖、盐藻、牛鞭、阿胶、杏仁、乌梢蛇、林蛙油、三七、芡实、山药、核桃仁、桃仁、淫羊藿、肉苁蓉、当归、白术、白果、乌梅、黑芝麻、沙棘、龙眼肉、决明子、橘红和熟地。本发明所述的中药组合物的效果显著、安全,无明显毒副作用。

Description

一种治疗美容养颜、强身健体、延年益寿的中药组合物
技术领域
本发明涉及医药领域,具体来说涉及一种治疗美容养颜、强身健体、延年益寿的中药组合物。
背景技术
现代人的生活节奏快,工作压力大,加上熬夜和不良的生活习惯,很多年轻人都会出现气虚、体乏、精力不支的现象。为此,很多人就花大量钱去购买一些保健品进行调理身体,但是现有的一些保健品对身体有副作用。而且随着年龄的增加,骨病患者越来越多,因此需要开发研制新的药物来进行治疗。
发明内容
本发明的目的是提供一种治疗美容养颜、强身健体、延年益寿的中药组合物。
为了实现本发明的目的,本发明提供一种治疗美容养颜、强身健体、延年益寿的中药组合物,它包含下列重量份的物质:人参1~5份、玛咖1~5份、盐藻1~3份、牛鞭1~5份、阿胶1~3份、杏仁1~3份、乌梢蛇1~3份、林蛙油1~3份、三七1~3份、芡实1~5份、山药1~5份、核桃仁1~3份、桃仁1~3份、淫羊藿1~5份、肉苁蓉1~5份、当归1~5份、白术1~5份、白果1~3份、乌梅1~3份、黑芝麻1~5份、沙棘1~5份、龙眼肉1~5份、决明子1~3份、橘红1~3份和熟地1~3份。
优选地,本发明所述的治疗美容养颜、强身健体、延年益寿的中药组合物包含下列重量份的物质:人参3份、玛咖3份、盐藻2份、牛鞭3份、阿胶2份、杏仁2份、乌梢蛇2份、林蛙油2份、三七2份、芡实3份、山药3份、核桃仁2份、桃仁2份、淫羊藿3份、肉苁蓉3份、当归3份、白术3份、白果2份、乌梅2份、黑芝麻3份、沙棘3份、龙眼肉3份、决明子2份、橘红2份和熟地2份。
更优选地,本发明所述的治疗美容养颜、强身健体、延年益寿的中药组合物还包含下列重量份的物质:0.02份的6-((2-((3-(甲磺酰胺甲基)苯基)氨基)嘧啶-4-基)氧基)-1-萘甲酸。
最优选地,所述中药组合物可以是片剂、分散片、胶囊剂、丸剂或汤剂。
本发明还提供6-((2-((3-(甲磺酰胺甲基)苯基)氨基)嘧啶-4-基)氧基)-1-萘甲酸在制备治疗美容养颜、强身健体、延年益寿、老年骨关节炎的药物中的用途。
本发明所述的中药组合物的效果显著、安全,无明显毒副作用。
具体实施方式
下面通过实施例进一步说明本发明。应该理解的是,本发明的实施例是用于说明本发明而不是对本发明的限制。根据本发明的实质对本发明进行的简单改进都属于本发明要求保护的范围。除非另有说明,否则本发明中的百分数是重量百分数。
实施例
称取人参30克、玛咖30克、盐藻20克、牛鞭30克、阿胶20克、杏仁20克、乌梢蛇20克、林蛙油20克、三七20克、芡实30克、山药30克、核桃仁20克、桃仁20克、淫羊藿30克、肉苁蓉30克、当归30克、白术30克、白果20克、乌梅20克、黑芝麻30克、沙棘30克、龙眼肉30克、决明子20克、橘红20克和熟地20克,粉碎,过100目筛,混合均匀得到粉末。
实验例
强身健体的一个重要因素应该是腿脚灵活,但是随着年纪增加,患骨关节炎的人群越来越多。骨关节炎是力学与生物学因素共同作用的结果,目前认为TNF-α水平与病程和疾病的严重程度有关,骨关节炎后TNF-α水平明显增加。因此研究用药后TNF-α水平可以来评价药物的效果。
膝骨关节炎模型和给药
将清洁级(SPF)雄性Wistar大鼠(鼠龄5-6月,体质量170.0±20.5)分成6组:正常对照组(Normalcontrolgroup,NC)、模型对照组(Modelcontrolgroup,MC)、氨基葡萄糖对照组(Glucosaminecontrolgroup,GS)、给药组1、给药组2、给药组3。每组10只。除正常对照组外,向其余各组大鼠的右膝关节注射4重量%木瓜蛋白酶水溶液10μL和0.03mol/L的L-半胱氨酸水溶液,并且分别于第3、7天加强,造成骨关节炎模型。造模后第14天开始给药,各组给药量如下:正常组与模型组,给予生理盐水灌胃1mL/100g体重;氨基葡萄糖组,氨基葡萄糖1g加100mL生理盐水配制成混悬液,给予灌胃1mL/100g体重;给药组1,实施例的粉末10g加1000mL生理盐水配制成混悬液,给予灌胃1mL/100g体重;给药组2,0.02g的6-((2-((3-(甲磺酰胺甲基)苯基)氨基)嘧啶-4-基)氧基)-1-萘甲酸加1000mL生理盐水配制成混悬液,给予灌胃1mL/100g体重;给药组3,实施例的粉末5g和0.01g的6-((2-((3-(甲磺酰胺甲基)苯基)氨基)嘧啶-4-基)氧基)-1-萘甲酸加1000mL生理盐水配制成混悬液,给予灌胃1mL/100g体重。1次/日,连续给药30d,造模后第49天取材。
ELISA法检测TNF-α
在第49天将动物处死后,行腹主动脉采血,将所采血液3000r/min离心5min,取血清,置-80℃冰箱保存待测。具体操作步骤按试剂盒(TNF-αELISA试剂盒购自上海酶联生物科技有限公司)说明书进行。结果见下表。
组别 TNF-α(ng·L-1)
正常组 202.64±13.85
模型组 263.76±12.20
氨基葡萄糖组 224.62±11.28
给药组1 217.61±9.89
给药组2 206.38±8.27
给药组3 211.36±7.71

Claims (5)

1.一种治疗美容养颜、强身健体、延年益寿的中药组合物,其特征在于,它包含下列重量份的物质:人参1~5份、玛咖1~5份、盐藻1~3份、牛鞭1~5份、阿胶1~3份、杏仁1~3份、乌梢蛇1~3份、林蛙油1~3份、三七1~3份、芡实1~5份、山药1~5份、核桃仁1~3份、桃仁1~3份、淫羊藿1~5份、肉苁蓉1~5份、当归1~5份、白术1~5份、白果1~3份、乌梅1~3份、黑芝麻1~5份、沙棘1~5份、龙眼肉1~5份、决明子1~3份、橘红1~3份和熟地1~3份。
2.根据权利要求1所述的治疗美容养颜、强身健体、延年益寿的中药组合物,其特征在于,它包含下列重量份的物质:人参3份、玛咖3份、盐藻2份、牛鞭3份、阿胶2份、杏仁2份、乌梢蛇2份、林蛙油2份、三七2份、芡实3份、山药3份、核桃仁2份、桃仁2份、淫羊藿3份、肉苁蓉3份、当归3份、白术3份、白果2份、乌梅2份、黑芝麻3份、沙棘3份、龙眼肉3份、决明子2份、橘红2份和熟地2份。
3.根据权利要求1或2所述的治疗美容养颜、强身健体、延年益寿的中药组合物,其特征在于,它还包含下列重量份的物质:0.02份的6-((2-((3-(甲磺酰胺甲基)苯基)氨基)嘧啶-4-基)氧基)-1-萘甲酸。
4.根据权利要求3所述的治疗美容养颜、强身健体、延年益寿的中药组合物,其特征在于,所述中药组合物可以是片剂、分散片、胶囊剂、丸剂或汤剂。
5.6-((2-((3-(甲磺酰胺甲基)苯基)氨基)嘧啶-4-基)氧基)-1-萘甲酸在制备治疗美容养颜、强身健体、延年益寿的药物中的用途。
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