CN105411987A - Silk peptide moisture retention skin care product suitable for babies and preparation method therefor - Google Patents

Silk peptide moisture retention skin care product suitable for babies and preparation method therefor Download PDF

Info

Publication number
CN105411987A
CN105411987A CN201511016233.1A CN201511016233A CN105411987A CN 105411987 A CN105411987 A CN 105411987A CN 201511016233 A CN201511016233 A CN 201511016233A CN 105411987 A CN105411987 A CN 105411987A
Authority
CN
China
Prior art keywords
silk peptide
moisturizer
silk
baby
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201511016233.1A
Other languages
Chinese (zh)
Inventor
刘玲
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Wilder Trade Co Ltd
Original Assignee
Suzhou Wilder Trade Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Wilder Trade Co Ltd filed Critical Suzhou Wilder Trade Co Ltd
Priority to CN201511016233.1A priority Critical patent/CN105411987A/en
Publication of CN105411987A publication Critical patent/CN105411987A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

The invention provides a silk peptide moisture retention skin care product suitable for babies and a preparation method therefor. Concrete operation steps are as follows: firstly, degumming silk is dissolved in an enzyme solution, low-temperature enzymatic hydrolysis is carried out, dialysis, condensation and filtering are carried out, then a silk peptide solution is obtained, the silk peptide solution is subjected to freeze drying, and high-purity silk peptide powder is obtained; secondly, the high-purity silk peptide powder is grinded and added with distilled water, stirring is carried out for 5-10min, then heating is carried out, the mixture is heated to 50-65 DEG C, thermal insulation is carried out, lanolin, a honey extract product, a silk peptide surfactant, a green aseptic and liposomes are added, the obtained mixture is fully stirred and mixed uniformly, then citric acid is added, the pH value is adjusted to 6.5-7, the mixture is stirred continuously and cooled to the room temperature, vacuum defoamation is carried out, and a silk peptide moisture retention skin care product suitable for babies is obtained. The prepared silk peptide moisture retention skin care product employs natural green substances as raw materials, has no toxicity or stimulation, has good moisture retention effects and rapid absorption, has certain bacteria resistance and bacteriostasis functions, can be painted on baby skin directly and is suitable for daily nursing.

Description

Silk peptide Moisturizer that a kind of baby is suitable for and preparation method thereof
Technical field:
The invention belongs to hygienic article technical field, be specifically related to silk peptide Moisturizer that a kind of baby is suitable for and preparation method thereof.
Background technology:
Moisturizing is the important physiological function of skin, and the tender and lovely degree of skin mainly depends on the cuticular water content with epiderm skin, and keratodermatitis is very thin, and Bound moisture and free water are contained in the inside, and when Bound moisture reaches capacity state, unnecessary moisture can form free water.Moisturizing and the wettability power of human body skin depend primarily on nature moisturizing factor, and nature moisturizing factor is the low molecular weight substance that can combine with water.When skin lacks moisture, just need to use wetting agent to carry out the moisture content of regulation of skin.
Wetting agent is bibulous water-soluble substances, can give replenish water for skin, prevent xerosis cutis.Conventional wetting agent has 4 classes: 1. the oils and fats moisturizing preventing moisture from evaporating; 2. absorb the moisture-absorbing moisture-keeping of outside moisture; 3. in conjunction with the hydration moisturizing of hydration; 4. repair the reparation moisturizing of horn cell.Traditional wetting agent has glycerol, 1,2-PD, 1,3 butylene glycol, sorbitol, pyrrolidone sodium carboxylate, Polyethylene Glycol and sodium lactate etc., and mostly these wetting agents are synthetic.Novel wetting agent has aminoacid, chitin, Aloe, collagen protein, hyaluronic acid, hyaluronic acid, tea polyphenols and silk peptide etc.
Silk peptide is the hydrolyzate of natural silk; belong to natural green product; its main fundamental structure unit is aminoacid; high with the adhesion of water, moisture absorption and performance of keeping humidity are excellent, and to form structure similar due to the aminoacid in silk peptide molecule and the aminoacid in human body skin; therefore elastin laminin, collagen protein and the nature moisturizing factor in skin is substituted; play nutrition skin, improve skin activity, repair the effect of skin natural containment.
The disclosed silk peptide marten oil skin-care cream of Chinese patent CN1096669A (publication date 1994.12.28), outside the auxiliary agents such as the white oil in traditional skin lotion, glycerol, phosphate ester, also added silk peptide and ermine oil, obtain easily directly being absorbed the skin care item with superpower skin moistening by skin.The disclosed moisturizing glycerol of Chinese patent CN103054758A (publication date 2013.4.24), main containing glycerol, silk peptide, hyaluronic acid, green tea extract and the fragrant extract that changes, obtain oil content moderate, the skin protectant that moisture-keeping function is good, improves the problem that single glycerol moistening effect is undesirable.The disclosed natural silk peptide protein skin care agent of Chinese patent CN103385807A (publication date 2013.11.13), using silk peptide as primary raw material, by adding emulsifying agent, glycerol, titanium dioxide, ultra-fine calcium powder and Oleum Arachidis hypogaeae semen as auxiliary agent, obtain silk peptide albumen skin-protection product.
From above-mentioned prior art, what current silk peptide was many is combine with other materials, the effect of skin protection moisturizing is played as a kind of auxiliary material, the excellent properties of not outstanding silk peptide itself, and silk peptide belongs to a kind of natural green material, very applicable making baby skin protection product, add chemical assistant, can destroy the essence of its green natural on the contrary.
Summary of the invention:
The technical problem to be solved in the present invention is to provide silk peptide Moisturizer that a kind of baby is suitable for and preparation method thereof, select high purity as raw material, add the auxiliary agents such as lanoline, Mel, liposome, obtain nontoxic non-stimulated, moistening effect is good, absorbs fast, also has the silk peptide Moisturizer of certain antibacterial bacteriostatic function, directly can be applied in infant skin to use, be suitable for daily nursing.
For solving the problems of the technologies described above, technical scheme of the present invention is:
The silk peptide Moisturizer that baby is suitable for, is characterized in that, the component of described silk peptide Moisturizer, by weight, comprising:
Silk peptide 5-10, lanoline 3-8,
Mel extract 2-6, silk peptide surfactant 5-7,
Green preservatives 1-5, liposome 4-9,
Citric acid 2-4, distilled water 30-50.
Preferably, described silk peptide is high purity.
The preparation method of the silk peptide Moisturizer that the present invention also provides a kind of baby to be suitable for, is characterized in that: comprise the following steps:
(1) silkworm silk come unstuck is dissolved in enzymatic solution, low temperature enzymolysis, after dialysis thickening filtration, obtains silk peptide solution, obtain high purity by after the lyophilization of silk peptide solution;
(2) high purity is ground fine ground, add in distilled water, heating is started after stirring 5-10min, be incubated after being heated to 50-65 DEG C, add lanoline, Mel extract, silk peptide surfactant, green preservatives and liposome, be stirred well to mix homogeneously, then add citric acid and regulate pH value to 6.5-7, continue to stir and near room temperature, after vacuum defoamation, obtain the silk peptide Moisturizer that baby is suitable for.
Preferred as technique scheme, in described step (1), in silk peptide solution, the mass fraction of silk peptide is 5-10%.
Preferred as technique scheme, in described step (1), in silk peptide solution, the molecular weight of silk peptide is 500-3000Da.
Preferred as technique scheme, in described silk peptide, 100-2000Da part accounts for the 55-60% of all silk peptide.
Preferred as technique scheme, in described step (1), in high purity, heteroion content is less than 1%.
Preferred as technique scheme, in described step (2), described silk peptide surfactant is fats-amino acid surfactant.
Preferred as technique scheme, in described step (2), described green preservatives is chitosan and tea polyphenols.
Preferred as technique scheme, in described step (2), the silk peptide Moisturizer that baby is suitable for can be used as the carrier fluid of baby's preserving moisture and protecting skin water or baby wipes.
Compared with prior art, the present invention has following beneficial effect:
(1) main functional component of silk peptide Moisturizer that prepared by the present invention is silk peptide, containing more hydrophilic group in the face of silk peptide molecule side, silk peptide is made to have good moisture-keeping function, and the molecular weight of silk peptide, penetrating power is strong, can be combined, participate in and improve epithelial metabolism through horny layer with epithelial cell, trophocyte, makes skin wet, softness, high resilience and gloss.And silk peptide has good film property, protecting film can be formed on the surface of skin and hair, the acid film of protection skin self.
(2) lanoline is contained in the silk peptide Moisturizer that prepared by the present invention; lanoline and there is permeability; the deep layer that can penetrate to the skin instantaneously; nourishes rough skin; and the protecting film of silkiness is formed at skin surface; Mel extract can absorb moisture from environment, makes the humidity around skin reach more than 65%, has higher hygroscopicity.
(3) silk peptide surfactant selected by the surfactant in the silk peptide Moisturizer prepared of the present invention, on the promotion well-mixed basis of Multiple components, ensures the good characteristic of silk peptide.The present invention also adds natural antiseptic agent, prevents the pollution being subject to microorganism in use procedure, but does not use chemical reagent, select natural animal-plant extractant chitosan and tea polyphenols, also gives system certain bactericidal effect.
(4) all adopt natural green substance as raw material in the silk peptide Moisturizer that prepared by the present invention, do not adopt the chemical substance of synthetic, nontoxic non-stimulated, moistening effect is good, absorb fast, also there is certain antibacterial bacteriostatic function, directly can be applied in infant skin and use, be suitable for daily nursing.
Detailed description of the invention:
Describe the present invention in detail below in conjunction with specific embodiment, be used for explaining the present invention in this illustrative examples of the present invention and explanation, but not as a limitation of the invention.
Embodiment 1:
(1) silkworm silk come unstuck is dissolved in enzymatic solution, low temperature enzymolysis, the silk peptide solution that mass fraction is 5% is obtained after dialysis thickening filtration, wherein the molecular weight of silk peptide is 500-3000Da, 100-2000Da part accounts for 55% of all silk peptide, the high purity then will obtaining heteroion content after the lyophilization of silk peptide solution and be less than 1%.
(2) by weight, by fine ground for the high purity of 5 parts grinding, add in the distilled water of 30 parts, heating is started after stirring 5min, be incubated after being heated to 50 DEG C, add the liposome of the lanoline of 3 parts, the Mel extract of 2 parts, the fats-aminoacid silk peptide surfactant of 5 parts, the chitosan of 1 part and tea polyphenols green preservatives and 4 parts, be stirred well to mix homogeneously, then the citric acid adding 2 parts regulates pH value to 6.5, continue to stir and near room temperature, after vacuum defoamation, obtain the silk peptide Moisturizer that baby is suitable for.
Embodiment 2:
(1) silkworm silk come unstuck is dissolved in enzymatic solution, low temperature enzymolysis, the silk peptide solution that mass fraction is 10% is obtained after dialysis thickening filtration, wherein the molecular weight of silk peptide is 500-3000Da, 100-2000Da part accounts for 60% of all silk peptide, the high purity then will obtaining heteroion content after the lyophilization of silk peptide solution and be less than 1%.
(2) by weight, by fine ground for the high purity of 10 parts grinding, add in the distilled water of 50 parts, heating is started after stirring 10min, be incubated after being heated to 65 DEG C, add the liposome of the lanoline of 8 parts, the Mel extract of 6 parts, the fats-aminoacid silk peptide surfactant of 7 parts, the chitosan of 5 parts and tea polyphenols green preservatives and 9 parts, be stirred well to mix homogeneously, then the citric acid adding 4 parts regulates pH value to 7, continue to stir and near room temperature, after vacuum defoamation, obtain the silk peptide Moisturizer that baby is suitable for.
Embodiment 3:
(1) silkworm silk come unstuck is dissolved in enzymatic solution, low temperature enzymolysis, the silk peptide solution that mass fraction is 6% is obtained after dialysis thickening filtration, wherein the molecular weight of silk peptide is 500-3000Da, 100-2000Da part accounts for 57% of all silk peptide, the high purity then will obtaining heteroion content after the lyophilization of silk peptide solution and be less than 1%.
(2) by weight, by fine ground for the high purity of 7 parts grinding, add in the distilled water of 40 parts, heating is started after stirring 8min, be incubated after being heated to 55 DEG C, add the liposome of the lanoline of 5 parts, the Mel extract of 4 parts, the fats-aminoacid silk peptide surfactant of 6 parts, the chitosan of 3 parts and tea polyphenols green preservatives and 5 parts, be stirred well to mix homogeneously, then the citric acid adding 3 parts regulates pH value to 6.7, continue to stir and near room temperature, after vacuum defoamation, obtain the silk peptide Moisturizer that baby is suitable for.
Embodiment 4:
(1) silkworm silk come unstuck is dissolved in enzymatic solution, low temperature enzymolysis, the silk peptide solution that mass fraction is 7% is obtained after dialysis thickening filtration, wherein the molecular weight of silk peptide is 500-3000Da, 100-2000Da part accounts for 56% of all silk peptide, the high purity then will obtaining heteroion content after the lyophilization of silk peptide solution and be less than 1%.
(2) by weight, by fine ground for the high purity of 6 parts grinding, add in the distilled water of 35 parts, heating is started after stirring 7min, be incubated after being heated to 60 DEG C, add the liposome of the lanoline of 6 parts, the Mel extract of 6 parts, the fats-aminoacid silk peptide surfactant of 6 parts, the chitosan of 3 parts and tea polyphenols green preservatives and 6 parts, be stirred well to mix homogeneously, then the citric acid adding 4 parts regulates pH value to 6.8, continue to stir and near room temperature, after vacuum defoamation, obtain the silk peptide Moisturizer that baby is suitable for.
Embodiment 5:
(1) silkworm silk come unstuck is dissolved in enzymatic solution, low temperature enzymolysis, the silk peptide solution that mass fraction is 9% is obtained after dialysis thickening filtration, wherein the molecular weight of silk peptide is 500-3000Da, 100-2000Da part accounts for 57% of all silk peptide, the high purity then will obtaining heteroion content after the lyophilization of silk peptide solution and be less than 1%.
(2) by weight, by fine ground for the high purity of 7 parts grinding, add in the distilled water of 40 parts, heating is started after stirring 7min, be incubated after being heated to 65 DEG C, add the liposome of the lanoline of 5 parts, the Mel extract of 2 parts, the fats-aminoacid silk peptide surfactant of 7 parts, the chitosan of 3 parts and tea polyphenols green preservatives and 5 parts, be stirred well to mix homogeneously, then the citric acid adding 2 parts regulates pH value to 6.5, continue to stir and near room temperature, after vacuum defoamation, obtain the silk peptide Moisturizer that baby is suitable for.
Embodiment 6:
(1) silkworm silk come unstuck is dissolved in enzymatic solution, low temperature enzymolysis, the silk peptide solution that mass fraction is 10% is obtained after dialysis thickening filtration, wherein the molecular weight of silk peptide is 500-3000Da, 100-2000Da part accounts for 55% of all silk peptide, the high purity then will obtaining heteroion content after the lyophilization of silk peptide solution and be less than 1%.
(2) by weight, by fine ground for the high purity of 10 parts grinding, add in the distilled water of 30 parts, heating is started after stirring 10min, be incubated after being heated to 65 DEG C, add the liposome of the lanoline of 8 parts, the Mel extract of 2 parts, the fats-aminoacid silk peptide surfactant of 5 parts, the chitosan of 5 parts and tea polyphenols green preservatives and 9 parts, be stirred well to mix homogeneously, then the citric acid adding 2 parts regulates pH value to 7, continue to stir and near room temperature, after vacuum defoamation, obtain the silk peptide Moisturizer that baby is suitable for.
Embodiment 7:
(1) silkworm silk come unstuck is dissolved in enzymatic solution, low temperature enzymolysis, the silk peptide solution that mass fraction is 5% is obtained after dialysis thickening filtration, wherein the molecular weight of silk peptide is 500-3000Da, 100-2000Da part accounts for 55% of all silk peptide, the high purity then will obtaining heteroion content after the lyophilization of silk peptide solution and be less than 1%.
(2) by weight, by fine ground for the high purity of 10 parts grinding, add in the distilled water of 50 parts, heating is started after stirring 5min, be incubated after being heated to 50 DEG C, add the liposome of the lanoline of 3 parts, the Mel extract of 6 parts, the fats-aminoacid silk peptide surfactant of 5 parts, the chitosan of 1 part and tea polyphenols green preservatives and 9 parts, be stirred well to mix homogeneously, then the citric acid adding 3 parts regulates pH value to 6.7, continue to stir and near room temperature, after vacuum defoamation, obtain the silk peptide Moisturizer that baby is suitable for.
Embodiment 8:
(1) silkworm silk come unstuck is dissolved in enzymatic solution, low temperature enzymolysis, the silk peptide solution that mass fraction is 9% is obtained after dialysis thickening filtration, wherein the molecular weight of silk peptide is 500-3000Da, 100-2000Da part accounts for 58% of all silk peptide, the high purity then will obtaining heteroion content after the lyophilization of silk peptide solution and be less than 1%.
(2) by weight, by fine ground for the high purity of 7 parts grinding, add in the distilled water of 50 parts, heating is started after stirring 10min, be incubated after being heated to 60 DEG C, add the liposome of the lanoline of 8 parts, the Mel extract of 4 parts, the fats-aminoacid silk peptide surfactant of 6 parts, the chitosan of 4 parts and tea polyphenols green preservatives and 8 parts, be stirred well to mix homogeneously, then the citric acid adding 4 parts regulates pH value to 6.5, continue to stir and near room temperature, after vacuum defoamation, obtain the silk peptide Moisturizer that baby is suitable for.
After testing, the concentration of the silk peptide Moisturizer that the baby that prepared by embodiment 1-8 is suitable for, absorbance, moisturizing rate and as follows to irritating result of skin:
As seen from the above table, the moderate concentration of the silk peptide Moisturizer that baby prepared by the present invention is suitable for, clearly, very easily absorbs, and moisture retention is good, and non-stimulated to skin, is suitable for the daily moisturizing protection of baby.
Above-described embodiment is illustrative principle of the present invention and effect thereof only, but not for limiting the present invention.Any person skilled in the art scholar all without prejudice under spirit of the present invention and category, can modify above-described embodiment or changes.Therefore, such as have in art usually know the knowledgeable do not depart from complete under disclosed spirit and technological thought all equivalence modify or change, must be contained by claim of the present invention.

Claims (10)

1. the silk peptide Moisturizer that is suitable for of baby, it is characterized in that, the component of described silk peptide Moisturizer, by weight, comprising:
Silk peptide 5-10, lanoline 3-8,
Mel extract 2-6, silk peptide surfactant 5-7,
Green preservatives 1-5, liposome 4-9,
Citric acid 2-4, distilled water 30-50.
2. the silk peptide Moisturizer that is suitable for of a kind of baby according to claim 1, it is characterized in that, described silk peptide is high purity.
3. the preparation method of silk peptide Moisturizer that is suitable for of baby, is characterized in that: comprise the following steps:
(1) silkworm silk come unstuck is dissolved in enzymatic solution, low temperature enzymolysis, after dialysis thickening filtration, obtains silk peptide solution, obtain high purity by after the lyophilization of silk peptide solution;
(2) high purity is ground fine ground, add in distilled water, heating is started after stirring 5-10min, be incubated after being heated to 50-65 DEG C, add lanoline, Mel extract, silk peptide surfactant, green preservatives and liposome, be stirred well to mix homogeneously, then add citric acid and regulate pH value to 6.5-7, continue to stir and near room temperature, after vacuum defoamation, obtain the silk peptide Moisturizer that baby is suitable for.
4. the preparation method of silk peptide Moisturizer that is suitable for of a kind of baby according to claim 3, it is characterized in that: in described step (1), in silk peptide solution, the mass fraction of silk peptide is 5-10%.
5. the preparation method of silk peptide Moisturizer that is suitable for of a kind of baby according to claim 3, it is characterized in that: in described step (1), in silk peptide solution, the molecular weight of silk peptide is 500-3000Da.
6. the preparation method of silk peptide Moisturizer that is suitable for of a kind of baby according to claim 5, it is characterized in that, in described silk peptide, 100-2000Da part accounts for the 55-60% of all silk peptide.
7. the preparation method of silk peptide Moisturizer that is suitable for of a kind of baby according to claim 3, is characterized in that: in described step (1), in high purity, heteroion content is less than 1%.
8. the preparation method of silk peptide Moisturizer that is suitable for of a kind of baby according to claim 3, it is characterized in that: in described step (2), described silk peptide surfactant is fats-amino acid surfactant.
9. the preparation method of silk peptide Moisturizer that is suitable for of a kind of baby according to claim 3, it is characterized in that: in described step (2), described green preservatives is chitosan and tea polyphenols.
10. the preparation method of silk peptide Moisturizer that is suitable for of a kind of baby according to claim 3, it is characterized in that: in described step (2), the silk peptide Moisturizer that baby is suitable for can be used as the carrier fluid of baby's preserving moisture and protecting skin water or baby wipes.
CN201511016233.1A 2015-12-30 2015-12-30 Silk peptide moisture retention skin care product suitable for babies and preparation method therefor Pending CN105411987A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201511016233.1A CN105411987A (en) 2015-12-30 2015-12-30 Silk peptide moisture retention skin care product suitable for babies and preparation method therefor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201511016233.1A CN105411987A (en) 2015-12-30 2015-12-30 Silk peptide moisture retention skin care product suitable for babies and preparation method therefor

Publications (1)

Publication Number Publication Date
CN105411987A true CN105411987A (en) 2016-03-23

Family

ID=55490846

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201511016233.1A Pending CN105411987A (en) 2015-12-30 2015-12-30 Silk peptide moisture retention skin care product suitable for babies and preparation method therefor

Country Status (1)

Country Link
CN (1) CN105411987A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107375006A (en) * 2017-08-10 2017-11-24 佛山圣婕妮生物科技有限公司 Surfactant containing silk protein and preparation method thereof, cleaning supplies
CN108977488A (en) * 2018-09-03 2018-12-11 艾苛密(上海)健康科技股份有限公司 Skin is intensively repaired with elastin laminin and preparation method thereof
CN110496069A (en) * 2019-06-05 2019-11-26 王晓霞 A kind of poly- peptide stoste of small molecule and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103565652A (en) * 2013-09-15 2014-02-12 邹少兵 Hair washing and conditioning wet tissue
CN104027293A (en) * 2014-06-27 2014-09-10 王忠良 Whitening cosmetic and preparation method thereof
CN105106094A (en) * 2015-09-14 2015-12-02 叶芳 Novel skin care product for preventing skin dryness and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103565652A (en) * 2013-09-15 2014-02-12 邹少兵 Hair washing and conditioning wet tissue
CN104027293A (en) * 2014-06-27 2014-09-10 王忠良 Whitening cosmetic and preparation method thereof
CN105106094A (en) * 2015-09-14 2015-12-02 叶芳 Novel skin care product for preventing skin dryness and preparation method thereof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
余丽丽等: ""保湿因子与保湿化妆品"", 《中国化妆品》 *
张秀玲: ""丝蛋白与化妆品"", 《北京轻工业学院学报》 *
彭艳红等: ""皮肤天然保湿的研究概况"", 《中国中西医结合皮肤性病学杂志》 *
陈晓英等: ""浅论功能性化妆品的开发"", 《福建轻纺》 *
陈莉莉: ""以丝素蛋白为原料的氨基酸表面活性剂的合成与性能研究"", 《苏州大学 硕士学位论文》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107375006A (en) * 2017-08-10 2017-11-24 佛山圣婕妮生物科技有限公司 Surfactant containing silk protein and preparation method thereof, cleaning supplies
CN108977488A (en) * 2018-09-03 2018-12-11 艾苛密(上海)健康科技股份有限公司 Skin is intensively repaired with elastin laminin and preparation method thereof
CN108977488B (en) * 2018-09-03 2021-05-07 艾苛密(上海)健康科技股份有限公司 Elastin for intensive skin repair and preparation method thereof
CN110496069A (en) * 2019-06-05 2019-11-26 王晓霞 A kind of poly- peptide stoste of small molecule and preparation method thereof

Similar Documents

Publication Publication Date Title
CN103251530B (en) Moderate skin cream containing multiple kinds of pure natural plant extracts
CN103505403B (en) Epidermal growth factor composite liposome body and its preparation method and application
CN105411919A (en) Skin caring product made from roses and preparation method thereof
CN103637940B (en) A kind of bath gel
CN113117137A (en) Medical dressing containing recombinant human collagen and preparation method thereof
CN107468563A (en) A kind of anti-dandruff silk quality lubrication is without silicone oil shampoo
CN104906015A (en) Cubilose whitening and beautifying mask
CN110522655A (en) A kind of active peptides milk matrix lipid body essence lotion and preparation method thereof with blue-opalescent and Tyndall effect
CN107245394A (en) A kind of Multifunctional cold handmade soap containing the fiery sesame oil of deer oil and preparation method thereof
CN103479567B (en) Epidermal growth factor complex liposome and its preparation method and application
CN110522713A (en) One kind is crease-resistant to remove fat granule and black-eyed milk matrix lipid body eye cream and preparation method thereof
CN107213095A (en) A kind of net acne maintenance breast of oil-control
CN105411987A (en) Silk peptide moisture retention skin care product suitable for babies and preparation method therefor
CN105380887A (en) Purely-natural moisture-retaining toner and preparation method thereof
CN104873437A (en) Fructus-rosae-laevigatae skin cream and preparation method thereof
CN102319195B (en) Skin whitening and smoothing milky cream
CN106265472A (en) Clear and rich vigor moisturizer and preparation method thereof
CN105106063A (en) Folium cortex eucommiae containing whitening massage cream
CN102943009B (en) Essential oil soap with nourishing and moisturizing functions and method for preparing essential oil soap with nourishing and moisturizing functions
CN105362166A (en) Whitening cosmetic containing glycyrrhiza glabra
CN102058511A (en) Water outlet cream added with pearl hydrolysate liposome
CN105816374A (en) Phyllanthus emblica skin whitening sunscreen emulsion
CN105616323A (en) Silk sponge product for nourishing and caring skin and preparation method thereof
CN104922012A (en) Silk cosmetic sunscreen cream
CN105250172A (en) Witch hazel massage balsam

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20160323

RJ01 Rejection of invention patent application after publication