CN105410904B - Suitable for the granular calcium lactate compositionss that child replenishes the calcium - Google Patents
Suitable for the granular calcium lactate compositionss that child replenishes the calcium Download PDFInfo
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- CN105410904B CN105410904B CN201510819478.1A CN201510819478A CN105410904B CN 105410904 B CN105410904 B CN 105410904B CN 201510819478 A CN201510819478 A CN 201510819478A CN 105410904 B CN105410904 B CN 105410904B
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- calcium
- lactate
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- chinese crude
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- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title claims abstract description 92
- 229960005069 calcium Drugs 0.000 title claims abstract description 92
- 239000011575 calcium Substances 0.000 title claims abstract description 92
- 229910052791 calcium Inorganic materials 0.000 title claims abstract description 92
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 title claims abstract description 51
- 239000001527 calcium lactate Substances 0.000 title claims abstract description 50
- 235000011086 calcium lactate Nutrition 0.000 title claims abstract description 50
- 229960002401 calcium lactate Drugs 0.000 title claims abstract description 50
- 239000003814 drug Substances 0.000 claims abstract description 63
- 229940079593 drug Drugs 0.000 claims abstract description 49
- 239000008187 granular material Substances 0.000 claims abstract description 34
- 108010001441 Phosphopeptides Proteins 0.000 claims abstract description 25
- 239000002994 raw material Substances 0.000 claims abstract description 24
- 210000000952 spleen Anatomy 0.000 claims abstract description 23
- WGIWBXUNRXCYRA-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate Chemical class [Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WGIWBXUNRXCYRA-UHFFFAOYSA-H 0.000 claims abstract description 17
- 235000006076 zinc citrate Nutrition 0.000 claims abstract description 17
- 235000011090 malic acid Nutrition 0.000 claims abstract description 15
- 239000000203 mixture Substances 0.000 claims abstract description 15
- 235000013925 ferrous lactate Nutrition 0.000 claims abstract description 14
- 239000011746 zinc citrate Substances 0.000 claims abstract description 14
- 229940068475 zinc citrate Drugs 0.000 claims abstract description 14
- 235000001727 glucose Nutrition 0.000 claims abstract description 13
- 150000002304 glucoses Chemical class 0.000 claims abstract description 13
- 229940071162 caseinate Drugs 0.000 claims abstract description 12
- 230000001954 sterilising effect Effects 0.000 claims abstract description 11
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 11
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims abstract description 8
- 238000002156 mixing Methods 0.000 claims abstract description 8
- 238000002360 preparation method Methods 0.000 claims abstract description 8
- 239000007788 liquid Substances 0.000 claims description 22
- 229940116298 l- malic acid Drugs 0.000 claims description 17
- 235000013399 edible fruits Nutrition 0.000 claims description 13
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 12
- 210000000582 semen Anatomy 0.000 claims description 12
- 239000000243 solution Substances 0.000 claims description 11
- DKKCQDROTDCQOR-UHFFFAOYSA-L Ferrous lactate Chemical compound [Fe+2].CC(O)C([O-])=O.CC(O)C([O-])=O DKKCQDROTDCQOR-UHFFFAOYSA-L 0.000 claims description 9
- 239000004225 ferrous lactate Substances 0.000 claims description 9
- 229940037907 ferrous lactate Drugs 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 8
- 238000000746 purification Methods 0.000 claims description 8
- 239000005018 casein Substances 0.000 claims description 7
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims description 7
- 235000021240 caseins Nutrition 0.000 claims description 7
- 238000000855 fermentation Methods 0.000 claims description 7
- 230000004151 fermentation Effects 0.000 claims description 7
- 241000208340 Araliaceae Species 0.000 claims description 6
- 241000283690 Bos taurus Species 0.000 claims description 6
- 235000007164 Oryza sativa Nutrition 0.000 claims description 6
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 6
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 6
- 108010019160 Pancreatin Proteins 0.000 claims description 6
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 6
- 102000004142 Trypsin Human genes 0.000 claims description 6
- 108090000631 Trypsin Proteins 0.000 claims description 6
- 235000009392 Vitis Nutrition 0.000 claims description 6
- 241000219095 Vitis Species 0.000 claims description 6
- 239000007853 buffer solution Substances 0.000 claims description 6
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 6
- 210000003038 endothelium Anatomy 0.000 claims description 6
- 229940088598 enzyme Drugs 0.000 claims description 6
- 238000001704 evaporation Methods 0.000 claims description 6
- 230000008020 evaporation Effects 0.000 claims description 6
- 238000000605 extraction Methods 0.000 claims description 6
- 235000008434 ginseng Nutrition 0.000 claims description 6
- 230000003301 hydrolyzing effect Effects 0.000 claims description 6
- 238000004806 packaging method and process Methods 0.000 claims description 6
- 229940055695 pancreatin Drugs 0.000 claims description 6
- 235000009566 rice Nutrition 0.000 claims description 6
- 239000010409 thin film Substances 0.000 claims description 6
- 239000012588 trypsin Substances 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 230000007062 hydrolysis Effects 0.000 claims description 5
- 238000006460 hydrolysis reaction Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 240000007594 Oryza sativa Species 0.000 claims 1
- 229920000157 polyfructose Polymers 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 abstract description 30
- 230000000694 effects Effects 0.000 abstract description 30
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract description 22
- 235000013305 food Nutrition 0.000 abstract description 16
- 239000011701 zinc Substances 0.000 abstract description 16
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract description 15
- 229910052725 zinc Inorganic materials 0.000 abstract description 15
- 230000004060 metabolic process Effects 0.000 abstract description 9
- 239000013589 supplement Substances 0.000 abstract description 8
- 229910000640 Fe alloy Inorganic materials 0.000 abstract description 5
- KFZAUHNPPZCSCR-UHFFFAOYSA-N iron zinc Chemical compound [Fe].[Zn] KFZAUHNPPZCSCR-UHFFFAOYSA-N 0.000 abstract description 5
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 abstract description 4
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 abstract description 3
- 230000029087 digestion Effects 0.000 abstract description 3
- 239000001630 malic acid Substances 0.000 abstract description 3
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 abstract description 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract description 2
- 229910001424 calcium ion Inorganic materials 0.000 abstract description 2
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 241000700159 Rattus Species 0.000 description 11
- 230000009286 beneficial effect Effects 0.000 description 10
- 238000000034 method Methods 0.000 description 6
- 206010006956 Calcium deficiency Diseases 0.000 description 5
- 241000209094 Oryza Species 0.000 description 5
- 229930003316 Vitamin D Natural products 0.000 description 5
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 5
- 229910052500 inorganic mineral Inorganic materials 0.000 description 5
- 235000010755 mineral Nutrition 0.000 description 5
- 239000011707 mineral Substances 0.000 description 5
- 231100000331 toxic Toxicity 0.000 description 5
- 230000002588 toxic effect Effects 0.000 description 5
- 235000019166 vitamin D Nutrition 0.000 description 5
- 239000011710 vitamin D Substances 0.000 description 5
- 150000003710 vitamin D derivatives Chemical class 0.000 description 5
- 229940046008 vitamin d Drugs 0.000 description 5
- 238000002835 absorbance Methods 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 210000003608 fece Anatomy 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 239000011573 trace mineral Substances 0.000 description 4
- 235000013619 trace mineral Nutrition 0.000 description 4
- RUWKZSPFMDVLRC-UHFFFAOYSA-N 2-hydroxypropane-1,2,3-tricarboxylic acid;zinc Chemical compound [Zn].OC(=O)CC(O)(C(O)=O)CC(O)=O RUWKZSPFMDVLRC-UHFFFAOYSA-N 0.000 description 3
- 210000000481 breast Anatomy 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 102000014171 Milk Proteins Human genes 0.000 description 2
- 108010011756 Milk Proteins Proteins 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- SMHNUIFHMAGAFL-UHFFFAOYSA-N calcium;2-hydroxypropanoic acid Chemical compound [Ca].CC(O)C(O)=O SMHNUIFHMAGAFL-UHFFFAOYSA-N 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000001079 digestive effect Effects 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 210000003141 lower extremity Anatomy 0.000 description 2
- 239000011777 magnesium Substances 0.000 description 2
- 229910052749 magnesium Inorganic materials 0.000 description 2
- 229940099690 malic acid Drugs 0.000 description 2
- 235000021239 milk protein Nutrition 0.000 description 2
- 239000002366 mineral element Substances 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 206010053155 Epigastric discomfort Diseases 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N Lactic Acid Natural products CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- IMQLKJBTEOYOSI-UHFFFAOYSA-N Phytic acid Natural products OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000000181 anti-adherent effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 229940092124 calcium citrate malate Drugs 0.000 description 1
- 229960004494 calcium gluconate Drugs 0.000 description 1
- 239000004227 calcium gluconate Substances 0.000 description 1
- 235000013927 calcium gluconate Nutrition 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 description 1
- MPCMQXRREZMSPJ-UHFFFAOYSA-L calcium;2-hydroxybutanedioate;2-hydroxypropane-1,2,3-tricarboxylic acid;pentahydrate Chemical compound O.O.O.O.O.[Ca+2].[O-]C(=O)C(O)CC([O-])=O.OC(=O)CC(O)(C(O)=O)CC(O)=O MPCMQXRREZMSPJ-UHFFFAOYSA-L 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940001468 citrate Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 235000013409 condiments Nutrition 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 239000000174 gluconic acid Substances 0.000 description 1
- 235000012208 gluconic acid Nutrition 0.000 description 1
- 239000007952 growth promoter Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 235000020256 human milk Nutrition 0.000 description 1
- 210000004251 human milk Anatomy 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 229940001447 lactate Drugs 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- -1 milk acid calcium salt Chemical class 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 230000007830 nerve conduction Effects 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 239000002417 nutraceutical Substances 0.000 description 1
- 235000021436 nutraceutical agent Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000000467 phytic acid Substances 0.000 description 1
- 229940068041 phytic acid Drugs 0.000 description 1
- 235000002949 phytic acid Nutrition 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 208000007442 rickets Diseases 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 235000012976 tarts Nutrition 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 230000004102 tricarboxylic acid cycle Effects 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention relates to a kind of granular calcium lactate compositionss that replenishes the calcium suitable for child and preparation method thereof, in parts by weight, it includes following components：50 90 parts of calcium lactate, 0.5 1 parts of zinc citrates, 0.3 1 parts of ferrous lactates, 5 10 parts of phosphopeptide caseinates, 350 400 parts of glucoses, 20 40 parts of oligofructoses, 5 10 parts of L malic acids, edible Chinese crude drug granules of 10 30 parts of invigorating the spleen and benefiting QI, its preparation method is：A, edible Chinese crude drug granule is prepared, B, raw material mixing and sterilization；Compared with prior art, the present invention is by calsium supplement and Chinese medicine efficient combination, realize that Chinese and Western combines, food medicine is combined, phosphopeptide caseinate promotes calcium, ferrum, zinc-iron alloy solution, zinc citrate facilitating digestion absorbs, L malic acids promote Absorption And Metabolism, the edible Chinese medicine composition facilitating digestion of invigorating the spleen and benefiting QI absorbs, and citrate, malic acid, lactate and calcium ion easily form metastable calcium salt, insoluble calcium is suppressed to generate, preferably promote child to calcium, ferrum, zinc absorption, reach the effect of 1+1 ＞ 2.
Description
Technical field
A kind of the present invention relates to field of health care food, more particularly to granular calcium lactate compositionss that replenishes the calcium suitable for child.
Background technology
Human body is contained within several mineral materials, and wherein calcium is the most one kind of content.Why harder the skeleton and tooth of people be,
Mainly more calcareous relation is contained in the inside, and calcium is the main component for constituting skeleton and tooth.If child's calcium deficiency, tooth is given birth to
Long development can postpone, and some children did not also teethe more than 2 years old, and skeleton can also soften, serious formation ricketss, O shapes lower limb or X-shaped
Lower limb.Additionally, being required for calcareous participation at aspects such as nerve conduction, muscular movement, blood coagulation and metabolism.
Calcium deficiency is global nutrition problem, the universal calcium deficiency of Chinese, will solve the problems, such as that calcium deficiency must be while in terms of two
Set about, one for increasing the intake of calcium, and two is the absorption rate for improving calcium.Child be in skeleton and dental growth development
Important period, the requirement to calcium are more more than adult.Therefore it is necessary in time and suitably to child's supplement calcium.However, some
Although father and mother focus on replenishing the calcium to child, but child still has the performance of calcium deficiency, this is because they often only focus on increasing taking the photograph for calcium
Enter amount, do not improve the absorption rate of calcium, and calcium is only just easily to be absorbed in the presence of ionic formses, in neutral and alkalescence
Easily insoluble salt is formed with acid ion again in environment and be lost in, but the cereal in the diet of people contains substantial amounts of plant again
The high phosphorus composition such as acid, phytic acid, they are easily combined with calcium under the environment of small intestinal lower end PH7～8 and generate calcium phosphate and sink
Form sediment, this results in supplementary calcium major part and cannot be absorbed by the body.
There is more than 200 kinds of calsium supplement on domestic market, being conceived to mostly increases the intake of calcium, and improves the suction of calcium
Receive, the product category of utilization rate seldom, in recent years, some nutraceutical and health food manufacturer produce reinforcing calcium at which
Also vitamin D is strengthened simultaneously, it is therefore an objective to improve the absorption rate of calcium, this is up to the present to solve calcium absorption to utilize
Rate and the only method that adopts.However, although vitamin D has very important effect, vitamin D to the growth of skeleton
Excess intake can cause certain harm to kidney and bone, and daily ingestion of 25 μ g vitamin D is easy for causing poisoning adult for a long time, because
This, developmental youngsters and children, it is necessary to appropriate vitamin D under the guidance of doctor, this is just to the absorption of raising calcium, profit
There is very big restriction with rate.
In addition, ferrum and zinc are the mineral that Chinese most easily lack in addition to calcium, and if merely, excessively replenishing the calcium, can also be right
The absorption of ferrum and zinc affects, and this growth promoter to child is very unfavorable.
Content of the invention
The technical problem to be solved is to provide one kind and can effectively overcome general calsium supplement to ferrum and zinc-iron alloy solution
Potential for adverse effects, calcium absorption effect is more preferable, the granular calcium lactate that alimentary health-care function is preferably replenished the calcium suitable for child
Compositionss.
The technical scheme that the present invention solves above-mentioned technical problem is as follows：
A kind of granular calcium lactate compositionss that replenishes the calcium suitable for child, in parts by weight, it includes following components：50-90
Part calcium lactate, 0.5-1 part zinc citrates, 0.3-1 part ferrous lactates, 5-10 part phosphopeptide caseinates, 350-400 part glucoses,
20-40 part oligofructoses, 5-10 part L MALIC ACIDs, the edible Chinese crude drug granule of 10-30 part invigorating the spleen and benefiting QI.
Compared with prior art, the invention has the beneficial effects as follows：
Traditional calsium supplement and Chinese medicine are effectively combined into together by the granular calcium lactate compositionss in the present invention, in realization
West combines, food medicine is combined, not only comprising trace element such as calcium, ferrum, zinc, also comprising the casein for simultaneously facilitating calcium, ferrum, zinc-iron alloy solution
Phosphoeptide, promotes the zinc citrate of human consumption's absorption function, promotes food in the L MALIC ACID of people's body absorption metabolism, improves
The edible Chinese medicine composition of the invigorating the spleen and benefiting QI of human consumption's absorption function, and citrate, malic acid, lactate and calcium from
Son easily forms metastable refrigerated calcium citrate malate or citrated milk acid calcium salt, the generation for both having suppressed insoluble calcium to precipitate,
The absorption of calcium ion, the composition that these species differ widely is not affected to complement each other, preferably can promote under synergism again
Enter child to calcium, ferrum, zinc absorption, reach the effect of 1+1 ＞ 2.
On the basis of above-mentioned technical proposal, the present invention can also do following improvement.
Used as a kind of preferred implementation of the present invention, the calcium lactate is with rice gelatinizing saccharified liquid or the double enzymes of Semen Maydis powder
Hydrolyzed solution is fermentation raw material, is neutralized with Calcium Carbonate again, finally solution evaporation is obtained after fermentation obtains lactate buffer solution.
Using the beneficial effect of above-mentioned preferred version it is：Calcium lactate is obtained with food as fermenting raw materials, even if excess is taken
Any toxic and side effects will not be produced to human body also.
As the present invention another kind of preferred implementation, the phosphopeptide caseinate be with bovine casein as raw material,
After pancreatin or trypsin hydrolyzing refine, purification and make.
Using the beneficial effect of above-mentioned preferred version it is：Phosphopeptide caseinate derives from milk protein, even if excess clothes
With also any toxic and side effects will not be produced to human body.
Used as another kind of preferred implementation of the present invention, the L MALIC ACID is with the serosity of immature fruit as original
Material, after being extracted by extraction refine, purification and make.
Using the beneficial effect of above-mentioned preferred version it is：L MALIC ACID derives from natural fruits, even if excess is taken also not
Any toxic and side effects can be produced to human body.
Used as another kind of preferred implementation of the present invention, the crude fruit is actually selected from Fructus Crataegi, Portugal one or more
Immature fruit in grape, Fructus Persicae or Fructus Mali pumilae.
Using the beneficial effect of above-mentioned preferred version it is：L MALIC ACID is almost present in all fruits, with pomaceous fruit in
At most, it is in hgher efficiency that L MALIC ACID is extracted from Fructus Crataegi, Fructus Vitis viniferae, Fructus Persicae or Fructus Mali pumilae.
Used as another kind of preferred implementation of the present invention, the edible Chinese crude drug granule is selected from by one or more
Chinese crude drug essence in Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri tangerinae, Rhizoma Dioscoreae, Fructus Mume, Semen Nelumbinis, Fructus Citri Sarcodactylis, Endothelium Corneum Gigeriae Galli, Fructus Amomi, Semen Coiciss, Fructus Crataegi or Poria
System is formed
Using the beneficial effect of above-mentioned preferred version it is：Above-mentioned Chinese crude drug is food and medicament dual-purpose, has no toxic side effect, and has
There is the drug effect of invigorating the spleen and benefiting QI, human digestive function can be improved, promote calcium absorption.
A kind of preparation method of the granular calcium lactate compositionss that replenishes the calcium suitable for child as above, it includes following step
Suddenly：
A, prepare edible Chinese crude drug granule
The edible Chinese crude drug of spleen invigorating QI invigorating is first taken, is placed in after chopping or crushing in decoction container, is added water and boil, then
Fried liquid is filtrated to get, finally concentrated, dry, that is, obtain described edible Chinese crude drug granule；
B, raw material mixing and sterilization
In parts by weight, take the edible Chinese crude drug granule described in 10-30 parts, and with 50-90 part calcium lactate, 0.5-1
Part zinc citrate, 0.3-1 part ferrous lactates, 5-10 part phosphopeptide caseinates, 350-400 part glucoses, the oligomeric fruit of 20-40 parts
Sugar, 5-10 part L MALIC ACIDs are mixed, be sufficiently mixed uniform after, sterilization, packaging obtain described replenishing the calcium suitable for child
Granular calcium lactate compositionss.
Compared with prior art, the invention has the beneficial effects as follows：
The method for preparing granular calcium lactate compositionss in the present invention is simple to operate, by trace element such as calcium, ferrum, zinc, can
The phosphopeptide caseinate of calcium, ferrum, zinc-iron alloy solution is simultaneously facilitated, the zinc citrate of human consumption's absorption function can be promoted, promote food
L MALIC ACID of the thing in people's body absorption metabolism, can improve the edible Chinese crude drug of the invigorating the spleen and benefiting QI of human consumption's absorption function
Composition is effectively combined into together, realizes that Chinese and Western combines, food medicine is combined, and the composition that these species differ widely complements each other, in association
Preferably can promote under same-action child to calcium, ferrum, zinc absorption, reach the effect of 1+1 ＞ 2.
Used as another kind of preferred implementation of the present invention, in step, the fried liquid is concentrated to using centrifugal thin-film
20%-40%.
Using the beneficial effect of above-mentioned preferred version it is：It is dried after being concentrated to this concentration again and can be more prone to, is improved
Efficiency.
Used as another kind of preferred implementation of the present invention, in step, using spray drying, inlet temperature is 110-
160 DEG C, leaving air temp is 70-90 DEG C.
Using the beneficial effect of above-mentioned preferred version it is：Not only drying effect is good, efficiency high, and will not destroy edible
The activity of Chinese crude drug granule.
Used as another kind of preferred implementation of the present invention, in stepb, the sterilization is specially in 90-95 DEG C of condition
Lower sterilization 10-15s.
Using the beneficial effect of above-mentioned preferred version it is：Not only bactericidal effect is good, and will not destroy particulate composition
Activity.
Below the present invention is described in further details.
A kind of granular calcium lactate compositionss that replenishes the calcium suitable for child, in parts by weight, it includes following components：50-90
Part calcium lactate, 0.5-1 part zinc citrates, 0.3-1 part ferrous lactates, 5-10 part phosphopeptide caseinates, 350-400 part glucoses,
20-40 part oligofructoses, 5-10 part L MALIC ACIDs, the edible Chinese crude drug granule of 10-30 part invigorating the spleen and benefiting QI；
Wherein, the calcium lactate is with rice gelatinizing saccharified liquid or Semen Maydis powder double-enzyme hydrolysis liquid as fermentation raw material, by sending out
Ferment is neutralized with Calcium Carbonate after obtaining lactate buffer solution again, and finally solution evaporation is obtained；
The phosphopeptide caseinate be with bovine casein as raw material, after pancreatin or trypsin hydrolyzing refine, pure
Change and make；
The L MALIC ACID is with the serosity of one or more immature fruit in Fructus Crataegi, Fructus Vitis viniferae, Fructus Persicae or Fructus Mali pumilae
For raw material, refine after being extracted by extraction, purification and make；
The edible Chinese crude drug granule by one or more selected from Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri tangerinae, Rhizoma Dioscoreae, Fructus Mume, Semen Nelumbinis,
Chinese crude drug in Fructus Citri Sarcodactylis, Endothelium Corneum Gigeriae Galli, Fructus Amomi, Semen Coiciss, Fructus Crataegi or Poria is refined and is formed.
A kind of preparation method of the granular calcium lactate compositionss that replenishes the calcium suitable for child as above, it includes following step
Suddenly：
A, prepare edible Chinese crude drug granule
The edible Chinese crude drug of spleen invigorating QI invigorating is first taken, is placed in after chopping or crushing in decoction container, is added water and boil, then
Be filtrated to get fried liquid, then the fried liquid be concentrated to 20%-40% using centrifugal thin-film, finally inlet temperature be 110-
160 DEG C, leaving air temp be to be spray-dried under conditions of 70-90 DEG C, that is, obtain described edible Chinese crude drug granule；
B, raw material mixing and sterilization
In parts by weight, take the edible Chinese crude drug granule described in 10-30 parts, and with 50-90 part calcium lactate, 0.5-1
Part zinc citrate, 0.3-1 part ferrous lactates, 5-10 part phosphopeptide caseinates, 350-400 part glucoses, the oligomeric fruit of 20-40 parts
Sugar, 5-10 part L MALIC ACIDs are mixed, and after being sufficiently mixed uniformly, sterilize under the conditions of 90-95 DEG C 10-15s, and packaging is obtained final product
To the granular calcium lactate compositionss that replenishes the calcium suitable for child.
In the present invention, used as food Creta Preparata, calcium absorptivity is very high for calcium lactate, and assimilation effect is than inorganic calcium, gluconic acid
Calcium is good；, used as food ferrous-fortifier, assimilation effect is better than inorganic iron for ferrous lactate；And zinc citrate is used as organic zinc tonic, right
Gastric irritation is little, and zinc content is high, and in human body participates in tricarboxylic acid cycle, strengthens human consumption's absorption function, and citric acid
Zinc is the presence of the unique a kind of Zn complex in human mother's milk, than milk in zinc more easily absorb, stable performance also has
Anti- adhesive feature, is particularly well-suited to manufacture powdery mixed food, ferrum, zinc simultaneously famine when, can from zinc citrate
Avoid playing antagonism with ferrum.
In the present invention, phosphopeptide caseinate can promote the absorption of small intestinal, skeleton, tooth to calcium, from milk protein,
Even if excess is taken also will not produce any toxic and side effects to human body, the Absorption of calcium is mainly shown as in neutral and weak base
Property environment under can be combined with calcium, suppress infusible precipitate generation, it is to avoid the loss of calcium, finally because of the raising of free calcium concentration
Passive intake；It can also improve the absorption rate of ferrum and zinc simultaneously, so as to effectively overcome general calsium supplement to ferrum, zinc-iron alloy solution
Potential for adverse effects, this point is the characteristic that any other calsium supplement does not possess；Additionally, it has in very wide pH scopes
The characteristic being inside completely dissolved, can tolerate high-temperature process, with good stability.
In the present invention, oligofructose can both improve product taste as novel sweetener, reduce food calorific value, can reach again
To the effect for promoting the mineral such as calcium, magnesium, ferrum and trace elements absorption, it is possible to promote in vivo the compound dimension life of synthesis B classes naturally
Element, with the effect for supporting that brain, nervous system activity, facilitating digestion and energy are generated.
Important composition of the L MALIC ACID for natural fruit juice in the present invention, tart flavour is stronger than citric acid by 20%, but taste is soft, tool
Peat-reek, does not damage oral cavity and tooth, not only there is acid condiment, the effect of antistaling agent, moreover it is possible to promote food in human body
Interior Absorption And Metabolism, and the acid condition of malic acid is advantageously in human body to calcareous absorption；In addition, typically adding in medicine
Plus L MALIC ACID can increase its stability, promote medicine in absorption, the diffusion of human body.
The edible Chinese crude drug granule of invigorating the spleen and benefiting QI in the present invention is decocted using the edible Chinese crude drug of invigorating the spleen and benefiting QI
Concentration refine afterwards is formed, and is added it in calsium supplement, can not only be ensured drug effect, improves human digestive function, is promoted calcareous
Etc. alimentation, and then strengthen skeleton, and take convenient.
The edible Chinese medicine composition of invigorating the spleen and benefiting QI in the present invention is combined with phosphopeptide caseinate, can greatly promote calcium,
The effect that the mineral elements such as zinc, ferrum absorb, reaches the effect of 1+1 ＞ 2；The edible Chinese medicine composition of invigorating the spleen and benefiting QI with oligomeric
Fructose is combined, and can be greatly promoted the effect of the mineral such as calcium, magnesium, ferrum and trace elements absorption, be reached the effect of 1+1 ＞ 2；Strong
The edible Chinese medicine composition of spleen QI invigorating is combined with L MALIC ACID, can greatly promote food in people's body absorption metabolism, especially
It is to strengthen the effect absorbed by the mineral elements such as calcium, zinc, ferrum, reaches the effect of 1+1 ＞ 2；The edible Chinese medicine of invigorating the spleen and benefiting QI
Material composition is combined with zinc citrate, can greatly enhance human consumption's absorption function, is especially strengthened to mineral such as calcium, zinc, ferrum
The effect that prime element absorbs, reaches the effect of 1+1 ＞ 2.
Specific embodiment
Hereinafter the principle and feature of the present invention are described, example is served only for explaining the present invention, is not intended to limit
Determine the scope of the present invention.
Embodiment 1
A kind of granular calcium lactate compositionss that replenishes the calcium suitable for child, in parts by weight, it includes following components：50 parts of breasts
Sour calcium, 0.5 part of zinc citrate, 0.3 part of ferrous lactate, 5 parts of phosphopeptide caseinates, 350 parts of glucoses, 20 parts of oligofructoses, 5 parts
L MALIC ACID, the edible Chinese crude drug granule of 10 parts of invigorating the spleen and benefiting QI；
Wherein, the calcium lactate is with rice gelatinizing saccharified liquid or Semen Maydis powder double-enzyme hydrolysis liquid as fermentation raw material, by sending out
Ferment is neutralized with Calcium Carbonate after obtaining lactate buffer solution again, and finally solution evaporation is obtained；
The phosphopeptide caseinate be with bovine casein as raw material, after pancreatin or trypsin hydrolyzing refine, pure
Change and make；
The L MALIC ACID is with the serosity of one or more immature fruit in Fructus Crataegi, Fructus Vitis viniferae, Fructus Persicae or Fructus Mali pumilae
For raw material, refine after being extracted by extraction, purification and make；
The edible Chinese crude drug granule by one or more selected from Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri tangerinae, Rhizoma Dioscoreae, Fructus Mume, Semen Nelumbinis,
Chinese crude drug in Fructus Citri Sarcodactylis, Endothelium Corneum Gigeriae Galli, Fructus Amomi, Semen Coiciss, Fructus Crataegi or Poria is refined and is formed.
A kind of preparation method of the granular calcium lactate compositionss that replenishes the calcium suitable for child as above, it includes following step
Suddenly：
A, prepare edible Chinese crude drug granule
The edible Chinese crude drug of spleen invigorating QI invigorating is first taken, is placed in after chopping or crushing in decoction container, is added water and boil, then
Fried liquid is filtrated to get, then the fried liquid is concentrated to 20% using centrifugal thin-film, be finally 110 DEG C, go out in inlet temperature
Air temperature is obtained described edible Chinese crude drug granule for being spray-dried under conditions of 70 DEG C；
B, raw material mixing and sterilization
In parts by weight, take the edible Chinese crude drug granule described in 10 parts, and with 50 parts of calcium lactate, 0.5 part of citric acid
Zinc, 0.3 part of ferrous lactate, 5 parts of phosphopeptide caseinates, 350 parts of glucoses, 20 parts of oligofructoses, 5 parts of L MALIC ACIDs are mixed
Close, after being sufficiently mixed uniformly, sterilize under the conditions of 90 DEG C 15s, and packaging obtains the calcium lactate that replenishes the calcium suitable for child
Grain compositionss.
Embodiment 2
A kind of granular calcium lactate compositionss that replenishes the calcium suitable for child, in parts by weight, it includes following components：70 parts of breasts
Sour calcium, 0.7 part of zinc citrate, 0.6 part of ferrous lactate, 7.5 parts of phosphopeptide caseinates, 400 parts of glucoses, 40 parts of oligofructoses,
7.5 parts of L MALIC ACIDs, the edible Chinese crude drug granule of 20 parts of invigorating the spleen and benefiting QI；
Wherein, the calcium lactate is with rice gelatinizing saccharified liquid or Semen Maydis powder double-enzyme hydrolysis liquid as fermentation raw material, by sending out
Ferment is neutralized with Calcium Carbonate after obtaining lactate buffer solution again, and finally solution evaporation is obtained；
The phosphopeptide caseinate be with bovine casein as raw material, after pancreatin or trypsin hydrolyzing refine, pure
Change and make；
The L MALIC ACID is with the serosity of one or more immature fruit in Fructus Crataegi, Fructus Vitis viniferae, Fructus Persicae or Fructus Mali pumilae
For raw material, refine after being extracted by extraction, purification and make；
The edible Chinese crude drug granule by one or more selected from Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri tangerinae, Rhizoma Dioscoreae, Fructus Mume, Semen Nelumbinis,
Chinese crude drug in Fructus Citri Sarcodactylis, Endothelium Corneum Gigeriae Galli, Fructus Amomi, Semen Coiciss, Fructus Crataegi or Poria is refined and is formed.
A kind of preparation method of the granular calcium lactate compositionss that replenishes the calcium suitable for child as above, it includes following step
Suddenly：
A, prepare edible Chinese crude drug granule
The edible Chinese crude drug of spleen invigorating QI invigorating is first taken, is placed in after chopping or crushing in decoction container, is added water and boil, then
Fried liquid is filtrated to get, then the fried liquid is concentrated to 30% using centrifugal thin-film, be finally 135 DEG C, go out in inlet temperature
Air temperature is obtained described edible Chinese crude drug granule for being spray-dried under conditions of 80 DEG C；
B, raw material mixing and sterilization
In parts by weight, take the edible Chinese crude drug granule described in 20 parts, and with 70 parts of calcium lactate, 0.7 part of citric acid
Zinc, 0.6 part of ferrous lactate, 7.5 parts of phosphopeptide caseinates, 400 parts of glucoses, 40 parts of oligofructoses, 7.5 parts of L MALIC ACIDs are carried out
Mixing, after being sufficiently mixed uniformly, sterilize under the conditions of 92 DEG C 13s, and packaging obtains the calcium lactate that replenishes the calcium suitable for child
Particulate composition.
Embodiment 3
A kind of granular calcium lactate compositionss that replenishes the calcium suitable for child, in parts by weight, it includes following components：90 parts of breasts
Sour calcium, 1 part of zinc citrate, 1 part of ferrous lactate, 10 parts of phosphopeptide caseinates, 375 parts of glucoses, 30 parts of oligofructoses, 10 parts of L-
Malic acid, the edible Chinese crude drug granule of 30 parts of invigorating the spleen and benefiting QI；
Wherein, the calcium lactate is with rice gelatinizing saccharified liquid or Semen Maydis powder double-enzyme hydrolysis liquid as fermentation raw material, by sending out
Ferment is neutralized with Calcium Carbonate after obtaining lactate buffer solution again, and finally solution evaporation is obtained；
The phosphopeptide caseinate be with bovine casein as raw material, after pancreatin or trypsin hydrolyzing refine, pure
Change and make；
The L MALIC ACID is with the serosity of one or more immature fruit in Fructus Crataegi, Fructus Vitis viniferae, Fructus Persicae or Fructus Mali pumilae
For raw material, refine after being extracted by extraction, purification and make；
The edible Chinese crude drug granule by one or more selected from Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri tangerinae, Rhizoma Dioscoreae, Fructus Mume, Semen Nelumbinis,
Chinese crude drug in Fructus Citri Sarcodactylis, Endothelium Corneum Gigeriae Galli, Fructus Amomi, Semen Coiciss, Fructus Crataegi or Poria is refined and is formed.
A kind of preparation method of the granular calcium lactate compositionss that replenishes the calcium suitable for child as above, it includes following step
Suddenly：
A, prepare edible Chinese crude drug granule
The edible Chinese crude drug of spleen invigorating QI invigorating is first taken, is placed in after chopping or crushing in decoction container, is added water and boil, then
Fried liquid is filtrated to get, then the fried liquid is concentrated to 40% using centrifugal thin-film, be finally 160 DEG C, go out in inlet temperature
Air temperature is obtained described edible Chinese crude drug granule for being spray-dried under conditions of 90 DEG C；
B, raw material mixing and sterilization
In parts by weight, take the edible Chinese crude drug granule described in 30 parts, and with 90 parts of calcium lactate, 1 part of zinc citrate,
1 part of ferrous lactate, 10 parts of phosphopeptide caseinates, 375 parts of glucoses, 30 parts of oligofructoses, 10 parts of L MALIC ACIDs are mixed, and are filled
After dividing mix homogeneously, sterilize under the conditions of 95 DEG C 10s, and packaging obtains the granular calcium lactate group that replenishes the calcium suitable for child
Compound.
Embodiment 4
The cleaning rat 30 of 4 week old is chosen, body weight 80-90g is randomly divided into three groups, per group each 10；1 group of rat is
Matched group, feeds normal feedstuff, and 2 groups of rats feed the normal feedstuff for being added with common lactic acid calcium powder, and 3 groups of rats feed and are added with the present invention
Granular calcium lactate compositionss group normal feedstuff；Determined normal feedstuff, be added with common lactic acid calcium powder with EDTA methods simultaneously
Normal feedstuff, be added with the present invention granular calcium lactate compositionss group normal feedstuff calcium content, as a result respectively 0.91mg/
g、8.02mg/g、8.33mg/g.
The metabolic test of 3 days by a definite date, accurate recording Feed consumption and excrement, urinary volume after feeding 2 weeks, is carried out, and is divided
Hun Yun not keep sample, the calcium content voided excreta with EDTA method determination test rats, and calcium Retention=(feedstuff calcium intake-row
Go out calcium amount)/feedstuff calcium intake × 100%, every test data meansigma methodss are as shown in the table：
As seen from the experiment, 1 group of (matched group) feces, calcium content of urine are zero, illustrate contained by normal feedstuff
The completely inadequate metabolism of rat of calcium, entirely by rat resorption, it is more to close that this also demonstrates and feeds rat with matched somebody with somebody normal feedstuff
Suitable, because if the calcium contained by normal feedstuff is sufficiently used for metabolism of rat, then the calcium lactate for being added afterwards will be unable to by
Rat resorption, experiment also will be unable to go on.
Result of the test is it is also shown that 2 groups and 3 groups of feces, urine calcium content have compared with 1 group (matched group) significantly carries
Height, and the calcium content of 2 groups of feces, urine is more than 3 groups, it is possible thereby to calculate 3 groups of calcium amount retained more than 2 groups, finally counts
The calcium Retention for drawing is also 3 groups and is more than 2 groups, because the calcium retention ratio in animal body often reflects metabolism of the animal to calcium
Absorbance, thus, it can be known that rat is significantly larger than them to common to the absorbance of calcium in the granular calcium lactate compositionss of the present invention
The absorbance of calcium in granular calcium lactate, and calcium lactate, used as food Creta Preparata, calcium absorptivity is inherently very high, and assimilation effect is excellent
In other food Creta Preparatas such as inorganic calcium, calcium gluconate, therefore, the granular calcium lactate that replenishes the calcium suitable for child in the present invention
Compositionss substantially can be more significantly improve absorbance of the human body to calcium.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and
Within principle, any modification, equivalent substitution and improvements that is made etc. should be included within the scope of the present invention.
Claims (1)
1. a kind of granular calcium lactate compositionss that replenishes the calcium suitable for child, it is characterised in that in parts by weight, it include with the following group
Point：50 parts of calcium lactate, 0.5 part of zinc citrate, 0.3 part of ferrous lactate, 5 parts of phosphopeptide caseinates, 350 parts of glucoses, 20 parts low
Polyfructose., 5 parts of L MALIC ACIDs, the edible Chinese crude drug granule of 10 parts of invigorating the spleen and benefiting QI；
Wherein, the calcium lactate is with rice gelatinizing saccharified liquid or Semen Maydis powder double-enzyme hydrolysis liquid as fermentation raw material, by fermenting
Neutralized with Calcium Carbonate to after lactate buffer solution again, finally the obtained calcium lactate by solution evaporation；
The phosphopeptide caseinate be with bovine casein as raw material, after pancreatin or trypsin hydrolyzing refine, purification and
The phosphopeptide caseinate that makes；
The L MALIC ACID is with the serosity of one or more immature fruit in Fructus Crataegi, Fructus Vitis viniferae, Fructus Persicae or Fructus Mali pumilae as original
Material, is refined after being extracted by extraction, purification and the L MALIC ACID made；
The edible Chinese crude drug granule by one or more selected from Radix Ginseng, Radix Glycyrrhizae, Pericarpium Citri tangerinae, Rhizoma Dioscoreae, Fructus Mume, Semen Nelumbinis, Fructus Citri Sarcodactylis,
Chinese crude drug in Endothelium Corneum Gigeriae Galli, Fructus Amomi, Semen Coiciss, Fructus Crataegi or Poria is refined and is formed；
The preparation method of the granular calcium lactate compositionss is comprised the following steps：
A, prepare edible Chinese crude drug granule
The edible Chinese crude drug of spleen invigorating QI invigorating is first taken, is placed in after chopping or crushing in decoction container, is added water and boil, then filter
Fried liquid is obtained, 20%-40% is concentrated to using centrifugal thin-film, then using being spray-dried, inlet temperature is 110-160 DEG C, goes out
Air temperature is 70-90 DEG C, finally obtains described edible Chinese crude drug granule；
B, raw material mixing and sterilization
In parts by weight, take the edible Chinese crude drug granule described in 10 parts, and with 50 parts of calcium lactate, 0.5 part of zinc citrate,
0.3 part of ferrous lactate, 5 parts of phosphopeptide caseinates, 350 parts of glucoses, 20 parts of oligofructoses, 5 parts of L MALIC ACIDs are mixed, and are filled
After dividing mix homogeneously, sterilization, packaging obtain the granular calcium lactate compositionss that replenishes the calcium suitable for child.
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| CN106722991A (en) * | 2016-12-21 | 2017-05-31 | 赣州天润药业有限公司 | A kind of calcium tablet and preparation method thereof |
| CN107048410A (en) * | 2017-04-27 | 2017-08-18 | 北京市永康年健康科技有限责任公司 | One seed oyster milk calcium product and its preparation method and application |
| CN108522665A (en) * | 2018-02-22 | 2018-09-14 | 安徽中盛食用油科技有限公司 | A kind of sesame is replenished the calcium tea oil and preparation method thereof |
| CN108669403A (en) * | 2018-05-28 | 2018-10-19 | 广州富诺营养科技有限公司 | A kind of multivitamin effervescent tablet of iron content zinc calcium and its annular preparation and preparation method |
| CN109043442A (en) * | 2018-08-26 | 2018-12-21 | 重庆海航农业开发有限公司 | A kind of instant ginger decoction |
| CN109224052A (en) * | 2018-11-14 | 2019-01-18 | 湖北鼎世立华生物科技有限公司 | A kind of composition and preparation improving children's spleen and gastrointestinal tract and growth and development |
| CN110101086A (en) * | 2019-04-30 | 2019-08-09 | 彤博士健康产业河北有限公司 | A kind of composition and preparation method thereof of replenishing the calcium promoting calcium uptake |
| CN110679816A (en) * | 2019-10-29 | 2020-01-14 | 徐州三源医药科技集团有限公司 | Solid beverage capable of enhancing immunity and preparation method thereof |
| CN112754019A (en) * | 2020-12-23 | 2021-05-07 | 河南九天生物科技有限公司 | Composition containing 25 hydroxyl d3 and calcium gluconate and preparation method thereof |
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| CN103494052A (en) * | 2013-08-29 | 2014-01-08 | 安徽珠峰生物科技有限公司 | Polypeptide infant calcium supplement instant granule and its preparation method |
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| CN103494052A (en) * | 2013-08-29 | 2014-01-08 | 安徽珠峰生物科技有限公司 | Polypeptide infant calcium supplement instant granule and its preparation method |
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