CN105408345B - 用于治疗和/或护理皮肤的化合物及其化妆品或药物组合物 - Google Patents

用于治疗和/或护理皮肤的化合物及其化妆品或药物组合物 Download PDF

Info

Publication number
CN105408345B
CN105408345B CN201480033925.4A CN201480033925A CN105408345B CN 105408345 B CN105408345 B CN 105408345B CN 201480033925 A CN201480033925 A CN 201480033925A CN 105408345 B CN105408345 B CN 105408345B
Authority
CN
China
Prior art keywords
inci
cosmetically
pharmaceutically acceptable
compound
stereoisomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201480033925.4A
Other languages
English (en)
Chinese (zh)
Other versions
CN105408345A (zh
Inventor
蒙特埃尔 A·V·费雷尔
多梅内克 N·阿尔米尼亚纳
普切 J·塞布里安
登 内斯特 W·范
塞莱玛 C·卡雷诺
冈萨雷斯 R·德尔加多
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lubrizol Advanced Materials Inc
Original Assignee
Lubrizol Advanced Materials Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lubrizol Advanced Materials Inc filed Critical Lubrizol Advanced Materials Inc
Publication of CN105408345A publication Critical patent/CN105408345A/zh
Application granted granted Critical
Publication of CN105408345B publication Critical patent/CN105408345B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1021Tetrapeptides with the first amino acid being acidic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/044Suspensions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/06Emulsions
    • A61K8/068Microemulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14Liposomes; Vesicles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0815Tripeptides with the first amino acid being basic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CN201480033925.4A 2013-04-15 2014-04-15 用于治疗和/或护理皮肤的化合物及其化妆品或药物组合物 Active CN105408345B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13382138.9A EP2792684A1 (en) 2013-04-15 2013-04-15 Compounds useful in the treatment and/or care of the skin and their cosmetic or pharmaceutical compositions
EP13382138.9 2013-04-15
PCT/EP2014/057672 WO2014170347A1 (en) 2013-04-15 2014-04-15 Compounds useful in the treatment and/or care of the skin and their cosmetic or pharmaceutical compositions

Publications (2)

Publication Number Publication Date
CN105408345A CN105408345A (zh) 2016-03-16
CN105408345B true CN105408345B (zh) 2020-08-07

Family

ID=48227117

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480033925.4A Active CN105408345B (zh) 2013-04-15 2014-04-15 用于治疗和/或护理皮肤的化合物及其化妆品或药物组合物

Country Status (9)

Country Link
US (1) US9458194B2 (https=)
EP (2) EP2792684A1 (https=)
JP (1) JP6525433B2 (https=)
KR (1) KR102260346B1 (https=)
CN (1) CN105408345B (https=)
AU (1) AU2014255776B2 (https=)
CA (1) CA2908863C (https=)
ES (1) ES2639464T3 (https=)
WO (1) WO2014170347A1 (https=)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9486408B2 (en) * 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
KR102401259B1 (ko) * 2014-10-21 2022-05-24 닛산 가가쿠 가부시키가이샤 레지스트 하층막 형성 조성물
MX394677B (es) 2014-10-31 2025-03-24 Lubrizol Advanced Mat Inc Pelicula de poliuretano termoplastico para la liberacion de agentes activos a superficies de piel.
CN114515269A (zh) * 2015-04-06 2022-05-20 株式会社Lg生活健康 微针及其制造方法
US20180311358A1 (en) 2015-11-05 2018-11-01 Lubrizol Advanced Materials, Inc. Thermoformable dual network hydrogel compositions
BR112018015897B1 (pt) 2016-02-04 2022-03-03 Alastin Skincare, Inc Composição tópica anidra para promover a reparação da pele, composições tópicas para promover a restauração da pele, composição tópica para aliviar contusões causadas por um procedimento cosmético e uso das mesmas
CN106176274B (zh) * 2016-08-26 2020-04-10 深圳市维琪医药研发有限公司 一种具有抗敏作用的多肽组合物
KR102471845B1 (ko) 2016-10-04 2022-11-28 마리 케이 인코포레이티드 튼살 치료를 위한 방법 및 조성물
BR102017010169A2 (pt) * 2017-05-15 2019-02-26 Remer Consultores Assessoria Empresarial Ltda. composto, intermediário de síntese, uso na preparação de anticonvulsivante, composição farmacêutica anticonvulsivante
AU2017360346B2 (en) 2016-11-21 2023-11-23 Eirion Therapeutics, Inc. Transdermal delivery of large agents
WO2018101449A1 (ja) * 2016-11-30 2018-06-07 株式会社資生堂 肌特性解析方法
WO2018134265A1 (en) 2017-01-17 2018-07-26 Forrest Michael David Therapeutic inhibitors of the reverse mode of atp synthase
FR3065876B1 (fr) 2017-05-05 2020-08-14 Basf Beauty Care Solutions France Sas Utilisation d'un extrait de nephelium lappaceum pour augmenter la fermete de la peau et/ou des muqueuses
WO2019012149A1 (en) 2017-07-13 2019-01-17 Forrest Michael David THERAPEUTIC MODULATORS OF THE INVERSE MODE OF ATP SYNTHASE
KR102757675B1 (ko) 2017-08-03 2025-01-20 앨러스틴 스킨케어, 인크. 피부 이완 및 신체 윤곽의 개선을 위한 조성물 및 방법
CN108004282B (zh) * 2017-12-01 2021-02-05 中国农业科学院麻类研究所 一种制备灵芝子实体发酵物的方法、发酵物及其应用
US11103455B2 (en) 2018-08-02 2021-08-31 ALASTIN Skincare, Inc. Liposomal compositions and methods of use
IT201900008364A1 (it) * 2019-06-07 2020-12-07 Espikem S R L Peptidi bioattivi e composizioni che li comprendono
GB2586577B (en) * 2019-06-14 2024-03-27 Gelmetix Ltd Diagnosis and treatment
CN111596069B (zh) * 2020-06-03 2021-08-06 四川大学华西第二医院 Hsp10在pop早期预警、诊断、预后评估中的应用和产品
KR20220128405A (ko) * 2020-07-29 2022-09-20 카낙 테크놀로지스, 엘엘씨 화장용 사용을 위한 친지성 물질의 개선된 포뮬레이션
WO2022076713A1 (en) * 2020-10-08 2022-04-14 ALASTIN Skincare, Inc. Compositions and methods relating to stimulation of hyaluronic acid
WO2022086004A1 (ko) * 2020-10-19 2022-04-28 (주)릴리커버 맞춤형 화장품 서비스 제공 방법
US20250325469A1 (en) 2021-01-24 2025-10-23 Michael David FORREST Inhibitors of atp synthase - cosmetic and therapeutic uses
CN115670965B (zh) * 2021-05-17 2024-04-19 杭州朝与暮品牌管理有限公司 一种有效抑制IL-8、TNF-α和IL-6的皮肤抗炎组合物
FR3126309B1 (fr) * 2021-08-30 2024-03-08 Oreal COMPOSITION COSMÉTIQUE à BASE DE GLAUCINE, RETINOL ET PEPTIDES POUR COMBATTRE LE VIEILLISSEMENT DE LA PEAU
CN113876641A (zh) * 2021-11-05 2022-01-04 上海新高姿化妆品有限公司 一种具有抗皱紧致功效的化妆品组合物及其应用
KR102792530B1 (ko) * 2021-12-27 2025-04-08 (주)케어젠 피부 상태 개선 활성을 갖는 펩타이드 및 이의 용도
CN116120402B (zh) * 2022-11-04 2024-03-15 深圳市维琪科技股份有限公司 一种环肽及其组合物和用途
CN115594735B (zh) * 2022-11-25 2023-09-22 深圳市维琪科技股份有限公司 具有抗衰老作用的肽及其组合物和用途
CN116440019B (zh) * 2023-03-27 2024-12-27 广东馨柯生命科学有限公司 含咖啡豆发酵液醒肤咖Supferm COFE和活力咖的防脱生发出水霜及其制备方法
WO2024229256A1 (en) * 2023-05-03 2024-11-07 Glo Pharma, Inc. Methods and compositions for cosmetic applications
CN117338628B (zh) * 2023-12-05 2024-04-09 杭州湃肽生化科技有限公司 一种紧肤抗皱组合物及其应用
CN119143848B (zh) * 2023-12-26 2025-11-25 杭州湃肽生化科技有限公司 环七肽-4及其制备方法及应用
WO2026029259A1 (ko) * 2024-07-31 2026-02-05 주식회사 바이오비쥬 트로포엘라스틴 가교 활성을 갖는 생체 적합성 폴리머를 포함하는 조성물
CN119462983B (zh) * 2024-11-13 2025-09-23 成都大学 一种大枣改性酸性多糖及其制备方法和用途
CN119241661B (zh) * 2024-11-14 2025-08-01 云南贝泰妮生物科技集团股份有限公司 一种具有抗炎作用的环肽化合物及其制备方法和应用
KR102782681B1 (ko) * 2024-12-16 2025-03-19 주식회사 바이오비쥬 트로포엘라스틴 가교 활성을 갖는 생체 적합성 폴리머를 포함하는 기능성 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040126788A1 (en) 2002-08-13 2004-07-01 Schiemann William P. Fibulin-5 and uses thereof
WO2005069975A2 (en) 2004-01-23 2005-08-04 Massachusetts Eye & Ear Infirmary Lysyl oxidase-like 1 (loxl1) and elastogenesis
US7943590B2 (en) 2007-03-16 2011-05-17 Multi-Gene Vascular Systems Ltd. Compositions and methods for treating ophthalmic disorders
EP2740484A1 (en) * 2012-12-05 2014-06-11 Lipotec, S.A. Compounds useful in the treatment and/or care of the skin, hair and/or muccous membranes and their cosmetic or pharmaceutical compositions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
A synthetic peptide from transforming growth factor-β1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats.;Nerea Hermida等;《cardiovascular research》;20011109;第81卷;全文 *
Topical application of a peptide inhibitor of transforming growth factor-beta 1 ameliorates bleomycin-induced skin frbrosis.;Santiago begona等;《The journal of investigative dermatology》;20050901;第125卷(第3期);全文 *

Also Published As

Publication number Publication date
EP2986626B1 (en) 2017-06-07
CA2908863C (en) 2022-07-12
EP2792684A1 (en) 2014-10-22
CA2908863A1 (en) 2014-10-23
AU2014255776B2 (en) 2018-09-06
KR102260346B1 (ko) 2021-06-03
WO2014170347A1 (en) 2014-10-23
KR20150143752A (ko) 2015-12-23
CN105408345A (zh) 2016-03-16
US20160075738A1 (en) 2016-03-17
JP2016519105A (ja) 2016-06-30
US9458194B2 (en) 2016-10-04
JP6525433B2 (ja) 2019-06-05
EP2986626A1 (en) 2016-02-24
ES2639464T3 (es) 2017-10-26
AU2014255776A1 (en) 2015-10-22
BR112015025961A2 (pt) 2017-10-17

Similar Documents

Publication Publication Date Title
CN105408345B (zh) 用于治疗和/或护理皮肤的化合物及其化妆品或药物组合物
JP5864425B2 (ja) 皮膚、粘膜および/または毛髪の治療および/またはケアに使用するペプチド、ならびに化粧料または医薬品組成物におけるその使用
CN104968360B (zh) 用于治疗和/或护理皮肤、毛发和/或粘膜的化合物以及它们的化妆美容或药物组合物
CN103314005B (zh) 在皮肤和/或粘膜的治疗和/或护理中有用的肽以及它们在化妆品组合物或药用组合物中的用途
CN102317307B (zh) 用于治疗和/或护理皮肤、粘膜和/或头皮的肽及它们在美容组合物或药物组合物中的用途
JP7227903B2 (ja) 皮膚、毛髪、爪および/もしくは粘膜の処置ならびに/またはケアに有用な化合物
CN104023737B (zh) 抑制被激活受体的肽及其在化妆品组合物或药物组合物中的用途
CN108495646A (zh) 用于治疗和/或护理皮肤、毛发、指甲和/或粘膜的化合物
CN116829169A (zh) 一种合成肽以及它们的美容组合物或药用组合物及用途
CN120441656B (zh) 一种活性多肽及其组合物和用途
BR112015025961B1 (pt) Composto, composição cosmética ou farmacêutica, e, uso de um composto

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant