CN105395695A - 一种治疗胃部疼痛的中药组合物及其制备方法 - Google Patents
一种治疗胃部疼痛的中药组合物及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种治疗胃部疼痛的中药组合物,按重量份包括如下原料:生地1-3,颠茄草3-5,山乌龟4-6,胡椒1-3,独脚金6-8,鸡内金8-12,没药1-3,肉苁蓉1-3。
Description
技术领域
本发明涉及医药品的应用及制备领域,涉及一种治疗胃部疼痛的中药组合物。
背景技术
胃痛又称胃脘痛,是指上腹胃脘部近心窝处疼痛,中医认为胃痛是脾胃受损、气血不调所引起的胃脘部的疼痛,多以外感寒邪,饮食所伤、情志不畅和脾胃素虚等病因而引发,喜食辛辣燥热加上天气干燥,胃火不降;西医的急性胃炎、慢性胃炎、胃溃疡、十二指肠溃疡、功能性消化障碍等以上腹部疼痛为主要症状,属于中医学胃部疼痛范围。目前治疗胃部疼痛的方法有中医治疗和西医治疗,西医治疗一般以阿莫西林+奥美拉唑+甲硝唑,即三联疗法,制酸抗感染为主,基本只能缓解或者解除症状,并且长期服用抗生素,有伤胃气,导致患者不思饮食,营养不良,身体更加虚弱。中医以寒热虚实、寒热错杂,比较常见,但忽视了脾胃久虚,积淤不畅,仅仅平衡脾胃阴阳还不够。因此导致疗效不佳,大多数患者反馈仅是胃痛症状消失,但是饮食量不增,且消化吸收没有得到改善。
发明内容
本发明的目的在于提供一种治疗胃痛,且能改善食欲及消化吸收的中药组合物。
本发明通过如下技术方案实现的:
一种治疗胃部疼痛的中药组合物,包括以下重量份的原料:生地1-3,颠茄草3-5,山乌龟4-6,胡椒1-3,独脚金6-8,鸡内金8-12,没药1-3,肉苁蓉1-3。
优选的,包括以下重量份的原料:生地2,颠茄草4,山乌龟5,胡椒2,独脚金7,鸡内金10,没药2,肉苁蓉2。
本发明还提供一种治疗胃部疼痛的中药组合物的制备方法:包含下列工艺步骤:按配比关系取各重量份的生地,颠茄草,山乌龟,胡椒,独脚金,鸡内金,没药,肉苁蓉;加70%乙醇在60~65℃浸泡15分钟,回流提取2-3次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在70-100℃喷雾干燥或烘干,粉碎成70-100目的细粉,制粒后常规压片或装胶囊,即得。
本发明组方精妙,各组分协同作用,舒缓镇痛,补益通降,破积消淤,对于胃热脾虚者尤其适用。
具体实施方式
实施例1
(1)取生地1份、颠茄草3份、山乌龟4份、胡椒1份、独脚金6份、鸡内金8份、没药1份、肉苁蓉1份备用;
(2)加70%乙醇在60℃浸泡15分钟,回流提取2次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在70℃喷雾干燥或烘干,粉碎成70目的细粉,制粒后装胶囊,规格0.45g/粒.早中晚各3次,饭前服用,每次3-5粒。
实施例2
(1)取生地3份、颠茄草5份、山乌龟6份、胡椒3份、独脚金8份、鸡内金12份、没药3份、肉苁蓉3份备用;
(2)加70%乙醇在65℃浸泡15分钟,回流提取3次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在100℃喷雾干燥或烘干,粉碎成100目的细粉,制粒后装胶囊,规格0.45g/粒。
实施例3
(1)取生地2份、颠茄草4份、山乌龟5份、胡椒2份、独脚金7份、鸡内金10份、没药2份、肉苁蓉2份备用;
(2)加70%乙醇在62℃浸泡15分钟,回流提取2次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在80℃喷雾干燥或烘干,粉碎成90目的细粉,制粒后装胶囊,规格0.45g/粒。
临床疗效数据
1、治疗胃疼效果观察
1.1对象:胃部疼痛观测600人,以胃脘疼痛、胃酸过多和长期饮食气滞、大便先硬后溏、嗳气,胃部有烧灼感。
1.2治疗药物组成:生地200克、颠茄草400克、山乌龟500克、胡椒200克、独脚金700克、鸡内金1000克、没药200克、肉苁蓉200克。
将上述药物加70%乙醇在62℃浸泡15分钟,回流提取2次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在80℃喷雾干燥或烘干,粉碎成90目的细粉,制粒后装胶囊,规格0.45g/粒,早中晚各一次,饭前服用,每次3-5粒。
1.3疗效判断标准:
治愈:胃脘疼痛及其他症状消失,x线、钡餐造影或胃镜检查正常。
好转:胃痛缓解,发作减少、其他症状减轻。
未愈:x线、钡餐造影或胃镜检查同发病前一样,症状无改善和好转。
治疗胃痛600例效果
使用30天后,600例胃痛显效414例,好转134例,无效52例,显效率69%,好转率22%,总有效率91%。在使用过程中,所有使用者均反映胃口变好,食量增加,且大便形态和颜色有所改善。
Claims (3)
1.在一种治疗胃部疼痛的中药组合物,其特征在于,包括以下重量份的原料:生地1-3,颠茄草3-5,山乌龟4-6,胡椒1-3,独脚金6-8,鸡内金8-12,没药1-3,肉苁蓉1-3。
2.根据权利要求1所述的一种治疗胃部疼痛的中药组合物,其特征在于,包括以下重量份的原料:生地2,颠茄草4,山乌龟5,胡椒2,独脚金7,鸡内金10,没药2,肉苁蓉2。
3.根据权利要求1或2所述的一种治疗胃部疼痛的中药组合物的制备方法:其特征在于包含下列工艺步骤:按配比关系取各重量份的生地,颠茄草,山乌龟,胡椒,独脚金,鸡内金,没药,肉苁蓉;加70%乙醇在60~65℃浸泡15分钟,回流提取2-3次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在70-100℃喷雾干燥或烘干,粉碎成70-100目的细粉,制粒后常规压片或装胶囊,即得。
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CN106074853A (zh) * | 2016-08-10 | 2016-11-09 | 李建敏 | 一种治疗胃痛的中药组合物及其制备方法 |
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CN101985016A (zh) * | 2009-07-29 | 2011-03-16 | 王连文 | 治疗胃炎的散剂 |
CN103751547A (zh) * | 2014-01-21 | 2014-04-30 | 四川绿禾药业有限公司 | 一种降血脂的中药组合物及其制备方法 |
CN104644963A (zh) * | 2013-11-21 | 2015-05-27 | 青岛润鑫伟业科贸有限公司 | 一种健脾养胃的组合物 |
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CN1079664A (zh) * | 1993-05-25 | 1993-12-22 | 辛旺耀 | 一种治疗溃疡病和萎缩性胃炎的中成药 |
CN101985016A (zh) * | 2009-07-29 | 2011-03-16 | 王连文 | 治疗胃炎的散剂 |
CN104644963A (zh) * | 2013-11-21 | 2015-05-27 | 青岛润鑫伟业科贸有限公司 | 一种健脾养胃的组合物 |
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