CN105412836A - 一种治疗胃热的中药组合物及其制备方法 - Google Patents

一种治疗胃热的中药组合物及其制备方法 Download PDF

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CN105412836A
CN105412836A CN201510965062.0A CN201510965062A CN105412836A CN 105412836 A CN105412836 A CN 105412836A CN 201510965062 A CN201510965062 A CN 201510965062A CN 105412836 A CN105412836 A CN 105412836A
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李建敏
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Abstract

本发明公开了一种治疗胃热的中药组合物，按重量份包括如下原料：白术1-3，颠茄草3-5，芦根8-10，薄荷脑0.1-0.3，淮山6-8，茯苓8-12，郁金1-3，菟丝子1-3。

Description

一种治疗胃热的中药组合物及其制备方法
技术领域
本发明涉及医药品的应用及制备领域，涉及一种治疗胃热的中药组合物。
背景技术
胃痛又称胃脘痛，是指上腹胃脘部近心窝处疼痛，中医认为胃痛是脾胃受损、气血不调所引起的胃脘部的疼痛，多以外感寒邪，饮食所伤、情志不畅和脾胃素虚等病因而引发，加上现代人喜食辛辣燥烈，压力过大，胃部不适之人越来越多；西医的急性胃炎、慢性胃炎、胃溃疡、十二指肠溃疡、功能性消化障碍等以上腹部疼痛为主要症状，属于中医学胃热范围。目前治疗胃热的方法有中医治疗和西医治疗，西医治疗一般以阿莫西林+奥美拉唑+甲硝唑，即三联疗法，制酸抗感染为主，基本只能缓解或者解除症状，并且长期服用抗生素，有伤胃气，导致患者不思饮食，营养不良，身体更加虚弱。中医以寒热虚实、寒热错杂，比较常见，但忽视了脾胃久虚，积淤不畅，仅仅平衡脾胃阴阳还不够。因此导致疗效不佳，大多数患者反馈仅是胃痛症状消失，但是饮食量不增，且消化吸收没有得到改善。
发明内容
本发明的目的在于提供一种治疗胃痛，且能改善食欲及消化吸收的中药组合物。
本发明通过如下技术方案实现的：
一种治疗胃热的中药组合物，包括以下重量份的原料：白术1-3，颠茄草3-5，芦根8-10，薄荷脑0.1-0.3，淮山6-8，茯苓8-12，郁金1-3，菟丝子1-3。
优选的，包括以下重量份的原料：白术2，颠茄草4，芦根9，薄荷脑0.2，淮山7，茯苓10，郁金2，菟丝子2。
本发明还提供一种治疗胃热的中药组合物的制备方法：包含下列工艺步骤：按配比关系取各重量份的白术，颠茄草，芦根，薄荷脑，淮山，茯苓，郁金，菟丝子；加70％乙醇在60～65℃浸泡15分钟，回流提取2-3次，每次1小时，100目滤器滤过，得提取液；合并提取液，输入减压浓缩罐中减压回收,乙醇至无醇味，得浓缩液；将浓缩液在70-100℃喷雾干燥或烘干，粉碎成70-100目的细粉，制粒后常规压片或装胶囊，即得。
本发明组方精妙，各组分协同作用，舒缓镇痛，清胃降火，清淤消食，对于胃热脾虚者尤其适用。
具体实施方式
实施例1
(1)取白术1份、颠茄草3份、芦根8份、薄荷脑0.1份、淮山6份、茯苓8份、郁金1份、菟丝子1份备用；
(2)加70％乙醇在60℃浸泡15分钟，回流提取2次，每次1小时，100目滤器滤过，得提取液；合并提取液，输入减压浓缩罐中减压回收,乙醇至无醇味，得浓缩液；将浓缩液在70℃喷雾干燥或烘干，粉碎成70目的细粉，制粒后装胶囊，规格0.45g/粒。
实施例2
(1)取白术3份、颠茄草5份、芦根10份、薄荷脑0.3份、淮山8份、茯苓12份、郁金3份、菟丝子3份备用；
(2)加70％乙醇在65℃浸泡15分钟，回流提取3次，每次1小时，100目滤器滤过，得提取液；合并提取液，输入减压浓缩罐中减压回收,乙醇至无醇味，得浓缩液；将浓缩液在100℃喷雾干燥或烘干，粉碎成100目的细粉，制粒后装胶囊，规格0.45g/粒。
实施例3
(1)取白术2份、颠茄草4份、芦根9份、薄荷脑0.2份、淮山7份、茯苓10份、郁金2份、菟丝子2份备用；
(2)加70％乙醇在62℃浸泡15分钟，回流提取2次，每次1小时，100目滤器滤过，得提取液；合并提取液，输入减压浓缩罐中减压回收,乙醇至无醇味，得浓缩液；将浓缩液在80℃喷雾干燥或烘干，粉碎成90目的细粉，制粒后装胶囊，规格0.45g/粒。
临床疗效数据
1、治疗胃疼效果观察
1.1对象：胃热观测900人，以胃脘疼痛、胃酸过多和长期饮食气滞、大便先硬后溏、嗳气、胃部有烧灼感。
1.2治疗药物组成：白术200克、颠茄草400克、芦根900克、薄荷脑20克、淮山700克、茯苓1000克、郁金200克、菟丝子200克。
将上述药物加70％乙醇在62℃浸泡15分钟，回流提取2次，每次1小时，100目滤器滤过，得提取液；合并提取液，输入减压浓缩罐中减压回收,乙醇至无醇味，得浓缩液；将浓缩液在80℃喷雾干燥或烘干，粉碎成90目的细粉，制粒后装胶囊，规格0.45g/粒，早中晚各三次，饭前服用，每次3-5粒。
1.3疗效判断标准：
治愈：胃脘疼痛及其他症状消失，x线、钡餐造影或胃镜检查正常。
好转：胃痛缓解，发作减少、胃部灼烧感减轻，其他症状减轻。
未愈：x线、钡餐造影或胃镜检查同发病前一样，症状无改善
和好转。
治疗胃痛900例效果
使用30天后，900例胃痛显效678例，好转136例，无效86例，显效率75％，好转率15％，总有效率90％。在使用过程中，所有使用者均反映胃口变好，食量增加，且大便形态和颜色有所改善。

Claims (3)

1.一种治疗胃热的中药组合物，其特征在于，包括以下重量份的原料：白术1-3，颠茄草3-5，芦根8-10，薄荷脑0.1-0.3，淮山6-8，茯苓8-12，郁金1-3，菟丝子1-3。
2.根据权利要求1所述的一种治疗胃热的中药组合物，其特征在于，包括以下重量份的原料：白术2，颠茄草4，芦根9，薄荷脑0.2，淮山7，茯苓10，郁金2，菟丝子2。
3.根据权利要求1或2所述的一种治疗胃热的中药组合物的制备方法：其特征在于包含下列工艺步骤：按配比关系取各重量份的白术，颠茄草，芦根，薄荷脑，淮山，茯苓，郁金，菟丝子；加70%乙醇在60～65℃浸泡15分钟，回流提取2-3次，每次1小时，100目滤器滤过，得提取液；合并提取液，输入减压浓缩罐中减压回收,乙醇至无醇味，得浓缩液；将浓缩液在70-100℃喷雾干燥或烘干，粉碎成70-100目的细粉，制粒后常规压片或装胶囊，即得。
CN201510965062.0A 2015-12-21 2015-12-21 一种治疗胃热的中药组合物及其制备方法 Pending CN105412836A (zh)

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CN106075158A (zh) * 2016-08-10 2016-11-09 李建敏 一种治疗急性单纯性胃炎的中药组合物及其制备方法

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