CN106074853A - 一种治疗胃痛的中药组合物及其制备方法 - Google Patents

一种治疗胃痛的中药组合物及其制备方法 Download PDF

Info

Publication number
CN106074853A
CN106074853A CN201610649621.1A CN201610649621A CN106074853A CN 106074853 A CN106074853 A CN 106074853A CN 201610649621 A CN201610649621 A CN 201610649621A CN 106074853 A CN106074853 A CN 106074853A
Authority
CN
China
Prior art keywords
chinese medicine
medicine composition
composition treating
radix rehmanniae
rhizoma chuanxiong
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610649621.1A
Other languages
English (en)
Inventor
李建敏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610649621.1A priority Critical patent/CN106074853A/zh
Publication of CN106074853A publication Critical patent/CN106074853A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/44Ebenaceae (Ebony family), e.g. persimmon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/77Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

本发明公开了一种治疗胃痛的中药组合物,按重量份包括如下原料:熟地3‑5,颠茄草3‑5,柿蒂8‑10,胡椒1‑3,山楂6‑8,鸡内金8‑12,川芎1‑3,龙眼肉1‑3。

Description

一种治疗胃痛的中药组合物及其制备方法
技术领域
本发明涉及医药品的应用及制备领域,涉及一种治疗胃痛的中药组合物。
背景技术
胃痛又称胃脘痛,是指上腹胃脘部近心窝处疼痛,中医认为胃痛是脾胃受损、气血不调所引起的胃脘部的疼痛,多以外感寒邪,饮食所伤、情志不畅和脾胃素虚等病因而引发,加上现代人喜食生冷寒凉,压力过大,患胃痛之人越来越多;西医的急性胃炎、慢性胃炎、胃溃疡、十二指肠溃疡、功能性消化障碍等以上腹部疼痛为主要症状,属于中医学胃痛范围。目前治疗胃痛的方法有中医治疗和西医治疗,西医治疗一般以阿莫西林+奥美拉唑+甲硝唑,即三联疗法,制酸抗感染为主,基本只能缓解或者解除症状,并且长期服用抗生素,有伤胃气,导致患者不思饮食,营养不良,身体更加虚弱。中医以寒热虚实、寒热错杂,比较常见,但忽视了脾胃久虚,积淤不畅,仅仅平衡脾胃阴阳还不够。因此导致疗效不佳,大多数患者反馈仅是胃痛症状消失,但是饮食量不增,且消化吸收没有得到改善。
发明内容
本发明的目的在于提供一种治疗胃痛,且能改善食欲及消化吸收的中药组合物。
本发明通过如下技术方案实现的:
一种治疗胃痛的中药组合物,包括以下重量份的原料:熟地3-5,颠茄草3-5,柿蒂8-10,胡椒1-3,山楂6-8,鸡内金8-12,川芎1-3,龙眼肉1-3。
优选的,包括以下重量份的原料:熟地4,颠茄草4,柿蒂9,胡椒2,山楂7,鸡内金10,川芎2,龙眼肉2。
本发明还提供一种治疗胃痛的中药组合物的制备方法:包含下列工艺步骤:按配比关系取各重量份的熟地,颠茄草,柿蒂,胡椒,山楂,鸡内金,川芎,龙眼肉;加70%乙醇在60~65℃浸泡15分钟,回流提取2-3次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在70-100℃喷雾干燥或烘干,粉碎成70-100目的细粉,制粒后常规压片或装胶囊,即得。
本发明组方精妙,各组分协同作用,舒缓镇痛,暖胃健脾,清淤消食,对于胃寒脾虚者尤其适用。
具体实施方式
实施例1
(1)取熟地3份、颠茄草3份、柿蒂8份、胡椒1份、山楂6份、鸡内金8份、川芎1份、龙眼肉1份备用;
(2)加70%乙醇在60℃浸泡15分钟,回流提取2次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在70℃喷雾干燥或烘干,粉碎成70目的细粉,制粒后装胶囊,规格0.45g/粒.早中晚各3次,饭前服用,每次3-5粒。
实施例2
(1)取熟地5份、颠茄草5份、柿蒂10份、胡椒3份、山楂8份、鸡内金12份、川芎3份、龙眼肉3份备用;
(2)加70%乙醇在65℃浸泡15分钟,回流提取3次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在100℃喷雾干燥或烘干,粉碎成100目的细粉,制粒后装胶囊,规格0.45g/粒。
实施例3
(1)取熟地4份、颠茄草4份、柿蒂9份、胡椒2份、山楂7份、鸡内金10份、川芎2份、龙眼肉2份备用;
(2)加70%乙醇在62℃浸泡15分钟,回流提取2次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在80℃喷雾干燥或烘干,粉碎成90目的细粉,制粒后装胶囊,规格0.45g/粒。
临床疗效数据
1、治疗胃疼效果观察
1.1对象:胃痛观测800人,以胃脘疼痛、胃酸过多和长期饮食气滞、大便先硬后溏、嗳气。
1.2治疗药物组成:熟地400克、颠茄草400克、柿蒂900克、胡椒200克、山楂700克、鸡内金1000克、川芎200克、龙眼肉200克。
将上述药物加70%乙醇在62℃浸泡15分钟,回流提取2次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在80℃喷雾干燥或烘干,粉碎成90目的细粉,制粒后装胶囊,规格0.45g/粒,早中晚各一次,饭前服用,每次3-5粒。
1.3疗效判断标准:
治愈:胃脘疼痛及其他症状消失,x线、钡餐造影或胃镜检查正常。
好转:胃痛缓解,发作减少、其他症状减轻。
未愈:x线、钡餐造影或胃镜检查同发病前一样,症状无改善和好转。
治疗胃痛800例效果
使用30天后,800例胃痛显效628例,好转124例,无效48例,显效率79%,好转率16%,总有效率95%。在使用过程中,所有使用者均反映胃口变好,食量增加,且大便形态和颜色有所改善。

Claims (3)

1.一种治疗胃痛的中药组合物,其特征在于,包括以下重量份的原料:熟地3-5,颠茄草3-5,柿蒂8-10,胡椒1-3,山楂6-8,鸡内金8-12,川芎1-3,龙眼肉1-3。
2.根据权利要求1所述的一种治疗胃痛的中药组合物,其特征在于,包括以下重量份的原料:熟地4,颠茄草4,柿蒂9,胡椒2,山楂7,鸡内金10,川芎2,龙眼肉2。
3.根据权利要求1或2所述的一种治疗胃痛的中药组合物的制备方法:其特征在于包含下列工艺步骤:按配比关系取各重量份的熟地,颠茄草,柿蒂,胡椒,山楂,鸡内金,川芎,龙眼肉;加70%乙醇在60~65℃浸泡15分钟,回流提取2-3次,每次1小时,100目滤器滤过,得提取液;合并提取液,输入减压浓缩罐中减压回收,乙醇至无醇味,得浓缩液;将浓缩液在70-100℃喷雾干燥或烘干,粉碎成70-100目的细粉,制粒后常规压片或装胶囊,即得。
CN201610649621.1A 2016-08-10 2016-08-10 一种治疗胃痛的中药组合物及其制备方法 Pending CN106074853A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610649621.1A CN106074853A (zh) 2016-08-10 2016-08-10 一种治疗胃痛的中药组合物及其制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610649621.1A CN106074853A (zh) 2016-08-10 2016-08-10 一种治疗胃痛的中药组合物及其制备方法

Publications (1)

Publication Number Publication Date
CN106074853A true CN106074853A (zh) 2016-11-09

Family

ID=57456283

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610649621.1A Pending CN106074853A (zh) 2016-08-10 2016-08-10 一种治疗胃痛的中药组合物及其制备方法

Country Status (1)

Country Link
CN (1) CN106074853A (zh)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102580023A (zh) * 2012-02-21 2012-07-18 常熟市方塔涂料化工有限公司 一种治疗脾胃不和、脘腹胀痛的药物
CN105169200A (zh) * 2015-09-21 2015-12-23 董春年 一种治疗胃病的中药制剂
CN105395695A (zh) * 2015-12-21 2016-03-16 李建敏 一种治疗胃部疼痛的中药组合物及其制备方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102580023A (zh) * 2012-02-21 2012-07-18 常熟市方塔涂料化工有限公司 一种治疗脾胃不和、脘腹胀痛的药物
CN105169200A (zh) * 2015-09-21 2015-12-23 董春年 一种治疗胃病的中药制剂
CN105395695A (zh) * 2015-12-21 2016-03-16 李建敏 一种治疗胃部疼痛的中药组合物及其制备方法

Similar Documents

Publication Publication Date Title
CN103182065A (zh) 有效治疗胃及十二指肠溃疡的口服液
CN101130023A (zh) 党参温胃散
CN110301636A (zh) 具有保健功能的药食两用粉、制备方法及其应用
CN105362778A (zh) 一种治疗反流性胃炎的中药组合物及其制备方法
CN105381388A (zh) 一种治疗胃部不适的中药组合物及其制备方法
CN104815232A (zh) 一种治疗原发性肺动脉高压的中药制剂及其制备方法
CN104587339A (zh) 一种治疗化疗相关周围神经毒性的中药浸泡剂
CN106074981A (zh) 一种治疗浅表性胃炎的中药组合物及其制备方法
CN103251889A (zh) 一种治疗乳汁不通的中药组合物
CN103656226A (zh) 一种治疗干燥综合征复方药
CN106138533A (zh) 一种治疗胃胀痛的中药组合物及其制备方法
CN106924581A (zh) 一种治疗腹痛的药酒及其制备方法
CN106074853A (zh) 一种治疗胃痛的中药组合物及其制备方法
CN105395695A (zh) 一种治疗胃部疼痛的中药组合物及其制备方法
CN105343435A (zh) 一种用于治疗胃胀痛的中药组合物及其制备方法
CN105343434A (zh) 一种用于治疗胃痛的中药组合物及其制备方法
CN105396041A (zh) 一种治疗胃寒的中药组合物及其制备方法
CN105395733A (zh) 一种用于治疗胃炎的中药组合物及其制备方法
CN105412836A (zh) 一种治疗胃热的中药组合物及其制备方法
CN106177846A (zh) 一种治疗糜烂性胃炎的中药组合物及其制备方法
CN106109703A (zh) 一种治疗肥厚性胃炎的中药组合物及其制备方法
CN106177645A (zh) 一种治疗慢性胃炎的中药组合物及其制备方法
CN105343797A (zh) 一种用于治疗胃病的中药组合物及其制备方法
CN106109812A (zh) 一种治疗胃酸过多的中药组合物及其制备方法
CN104587251B (zh) 一种治疗痛风的中药胶囊及其制备方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20161109

WD01 Invention patent application deemed withdrawn after publication