CN105392500B - 成像神经学疾病 - Google Patents

成像神经学疾病 Download PDF

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Publication number
CN105392500B
CN105392500B CN201480041743.1A CN201480041743A CN105392500B CN 105392500 B CN105392500 B CN 105392500B CN 201480041743 A CN201480041743 A CN 201480041743A CN 105392500 B CN105392500 B CN 105392500B
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CN105392500A (zh
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M.J.罗瑟
J.沃尔贝尔
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GE Healthcare Ltd
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GE Healthcare Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/48—Diagnostic techniques
    • A61B6/481—Diagnostic techniques involving the use of contrast agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/501—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of the head, e.g. neuroimaging or craniography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5217—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data extracting a diagnostic or physiological parameter from medical diagnostic data
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Neurosurgery (AREA)
  • Dentistry (AREA)
  • Neurology (AREA)
  • Physiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nuclear Medicine (AREA)
  • Pulmonology (AREA)
  • Theoretical Computer Science (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Primary Health Care (AREA)
CN201480041743.1A 2013-07-25 2014-07-25 成像神经学疾病 Active CN105392500B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1313291.5A GB201313291D0 (en) 2013-07-25 2013-07-25 Imaging neurological disease
GB1313291.5 2013-07-25
PCT/EP2014/066042 WO2015011267A1 (en) 2013-07-25 2014-07-25 Imaging neurological disease

Publications (2)

Publication Number Publication Date
CN105392500A CN105392500A (zh) 2016-03-09
CN105392500B true CN105392500B (zh) 2023-08-18

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CN201480041743.1A Active CN105392500B (zh) 2013-07-25 2014-07-25 成像神经学疾病

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US (1) US11051777B2 (enExample)
EP (1) EP3024501B1 (enExample)
JP (1) JP6590801B2 (enExample)
KR (1) KR102340504B1 (enExample)
CN (1) CN105392500B (enExample)
AU (2) AU2014294983B2 (enExample)
BR (1) BR112016001316B1 (enExample)
CA (1) CA2916125A1 (enExample)
DK (1) DK3024501T3 (enExample)
ES (1) ES2722973T3 (enExample)
GB (1) GB201313291D0 (enExample)
IL (1) IL243383B (enExample)
MX (1) MX2016001012A (enExample)
RU (1) RU2015155792A (enExample)
SG (1) SG11201600571RA (enExample)
WO (1) WO2015011267A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104720840A (zh) * 2015-02-11 2015-06-24 清华大学深圳研究生院 基于多巴胺转运体显像特异性摄取比的半自动量化方法
TWI587841B (zh) * 2015-03-06 2017-06-21 國立陽明大學 定量分析核子醫學腦部影像的系統及方法
US20180000440A1 (en) * 2015-03-24 2018-01-04 Nihon Medi-Physics Co., Ltd. Image processing apparatus, image processing method, and program
KR101720288B1 (ko) 2016-05-11 2017-03-28 (주)바이오액츠 뇌 영상용 염료 및 이의 제조방법
JP6549521B2 (ja) * 2016-05-25 2019-07-24 富士フイルム富山化学株式会社 疾患鑑別支援装置及びコンピュータプログラム
TWI607739B (zh) * 2016-05-27 2017-12-11 許百靈 Ｓｐｅｃｔ多巴胺顯像定量分析技術與在腦多巴胺評估的用途
GB201621698D0 (en) * 2016-12-20 2017-02-01 Ge Healthcare Ltd (Ip) And Stichting Vumc And Acad Medical Center Differential Diagnosis
JP6995642B2 (ja) * 2018-01-19 2022-01-14 日本メジフィジックス株式会社 画像処理装置、画像処理方法およびプログラム
TWI686178B (zh) * 2019-10-09 2020-03-01 中原大學 自動化定位核子醫學腦部影像紋狀體與計算紋狀體專一性攝取率的方法與系統
US20230001026A1 (en) * 2019-11-21 2023-01-05 Likeminds, Inc. Pharmaceutical packaging units and methods for concomitant administration of radiotracers
AR125188A1 (es) 2021-03-22 2023-06-21 Neurocrine Biosciences Inc Inhibidores del vmat2 y métodos de uso
CN119599879B (zh) * 2024-11-06 2025-10-24 复旦大学附属华山医院 一种基于深度学习的pet图像跨膜态合成方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090110635A1 (en) * 2007-10-31 2009-04-30 Hurtt Jr Mark Methods for imaging dopamine transporter level
WO2009058851A2 (en) * 2007-10-31 2009-05-07 Alseres Pharmaceuticals, Inc. Methods for diagnosing and monitoring treatment of lewy body dementia by assessing dopamine transporter level
CN101918040A (zh) * 2007-09-26 2010-12-15 皇家飞利浦电子股份有限公司 鉴别诊断不同类型痴呆的方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101918040A (zh) * 2007-09-26 2010-12-15 皇家飞利浦电子股份有限公司 鉴别诊断不同类型痴呆的方法
US20090110635A1 (en) * 2007-10-31 2009-04-30 Hurtt Jr Mark Methods for imaging dopamine transporter level
WO2009058851A2 (en) * 2007-10-31 2009-05-07 Alseres Pharmaceuticals, Inc. Methods for diagnosing and monitoring treatment of lewy body dementia by assessing dopamine transporter level

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Decreased Single-Photon Emission Computed Tomographc [123I]β-CIT Striatal Uptake Correlates with Symptom Severity in Parkmson’s Disease;J.P. Seibyl et al;《Annals of Neurology》;19950620;第38卷(第4期);第589-498页 *

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Publication number Publication date
WO2015011267A1 (en) 2015-01-29
IL243383B (en) 2018-07-31
RU2015155792A3 (enExample) 2018-05-23
CA2916125A1 (en) 2015-01-29
US11051777B2 (en) 2021-07-06
GB201313291D0 (en) 2013-09-11
AU2014294983A1 (en) 2016-01-21
RU2015155792A (ru) 2017-08-30
JP6590801B2 (ja) 2019-10-16
HK1222118A1 (zh) 2017-06-23
ES2722973T3 (es) 2019-08-20
KR102340504B1 (ko) 2021-12-20
EP3024501A1 (en) 2016-06-01
KR20160037168A (ko) 2016-04-05
EP3024501B1 (en) 2019-03-27
DK3024501T3 (da) 2019-05-06
BR112016001316B1 (pt) 2021-04-06
US20160183897A1 (en) 2016-06-30
SG11201600571RA (en) 2016-02-26
JP2016531903A (ja) 2016-10-13
AU2014294983B2 (en) 2019-10-24
AU2019253837A1 (en) 2019-11-14
AU2019253837B2 (en) 2021-11-25
CN105392500A (zh) 2016-03-09
MX2016001012A (es) 2016-05-09

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