ES2722973T3 - Obtención de imágenes en enfermedades neurológicas - Google Patents
Obtención de imágenes en enfermedades neurológicas Download PDFInfo
- Publication number
- ES2722973T3 ES2722973T3 ES14742544T ES14742544T ES2722973T3 ES 2722973 T3 ES2722973 T3 ES 2722973T3 ES 14742544 T ES14742544 T ES 14742544T ES 14742544 T ES14742544 T ES 14742544T ES 2722973 T3 ES2722973 T3 ES 2722973T3
- Authority
- ES
- Spain
- Prior art keywords
- iii
- relationship
- subject
- stage
- neurological diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 208000012902 Nervous system disease Diseases 0.000 title abstract 3
- 208000025966 Neurological disease Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 210000001577 neostriatum Anatomy 0.000 abstract 2
- 102000006441 Dopamine Plasma Membrane Transport Proteins Human genes 0.000 abstract 1
- 108010044266 Dopamine Plasma Membrane Transport Proteins Proteins 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 229940121896 radiopharmaceutical Drugs 0.000 abstract 1
- 239000012217 radiopharmaceutical Substances 0.000 abstract 1
- 230000002799 radiopharmaceutical effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/481—Diagnostic techniques involving the use of contrast agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
- A61B6/501—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of the head, e.g. neuroimaging or craniography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
- A61B6/5217—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data extracting a diagnostic or physiological parameter from medical diagnostic data
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- High Energy & Nuclear Physics (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Neurosurgery (AREA)
- Dentistry (AREA)
- Neurology (AREA)
- Physiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nuclear Medicine (AREA)
- Pulmonology (AREA)
- Theoretical Computer Science (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Primary Health Care (AREA)
Abstract
Un método realizado por ordenador útil en el diagnóstico de enfermedades neurológicas, que comprende: (i) evaluar visualmente una imagen con radiofármaco para el transportador de dopamina en una región equivalente de: (A) la izquierda; y (B) la derecha; del cuerpo estriado del cerebro de un sujeto; (ii) calcular la relación de la captación en la región equivalente izquierda y derecha del cuerpo estriado de la etapa (i); (iii) comparar la relación para dicho sujeto de la etapa (ii) con una base de datos de dichas relaciones, en donde dicha base de datos contiene dichas relaciones para sujetos normales; (iv) cuando la relación de la etapa (iii) está dentro del intervalo normal, dicho sujeto se clasifica como que tiene una presentación normal; (v) cuando la relación de la etapa (iii) está fuera del intervalo normal, el paciente se clasifica como que padece una enfermedad neurológica; con la condición de que dicho método excluya otros análisis para realizar la comparación con pacientes/controles de la misma edad y del mismo género.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1313291.5A GB201313291D0 (en) | 2013-07-25 | 2013-07-25 | Imaging neurological disease |
| PCT/EP2014/066042 WO2015011267A1 (en) | 2013-07-25 | 2014-07-25 | Imaging neurological disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2722973T3 true ES2722973T3 (es) | 2019-08-20 |
Family
ID=49166921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14742544T Active ES2722973T3 (es) | 2013-07-25 | 2014-07-25 | Obtención de imágenes en enfermedades neurológicas |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US11051777B2 (es) |
| EP (1) | EP3024501B1 (es) |
| JP (1) | JP6590801B2 (es) |
| KR (1) | KR102340504B1 (es) |
| CN (1) | CN105392500B (es) |
| AU (2) | AU2014294983B2 (es) |
| BR (1) | BR112016001316B1 (es) |
| CA (1) | CA2916125A1 (es) |
| DK (1) | DK3024501T3 (es) |
| ES (1) | ES2722973T3 (es) |
| GB (1) | GB201313291D0 (es) |
| HK (1) | HK1222118A1 (es) |
| IL (1) | IL243383B (es) |
| MX (1) | MX2016001012A (es) |
| RU (1) | RU2015155792A (es) |
| SG (1) | SG11201600571RA (es) |
| WO (1) | WO2015011267A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104720840A (zh) * | 2015-02-11 | 2015-06-24 | 清华大学深圳研究生院 | 基于多巴胺转运体显像特异性摄取比的半自动量化方法 |
| TWI587841B (zh) * | 2015-03-06 | 2017-06-21 | 國立陽明大學 | 定量分析核子醫學腦部影像的系統及方法 |
| KR20170131829A (ko) * | 2015-03-24 | 2017-11-30 | 니혼 메디피직스 가부시키가이샤 | 화상 처리 장치, 화상 처리 방법, 및 프로그램 |
| KR101720288B1 (ko) | 2016-05-11 | 2017-03-28 | (주)바이오액츠 | 뇌 영상용 염료 및 이의 제조방법 |
| JP6549521B2 (ja) * | 2016-05-25 | 2019-07-24 | 富士フイルム富山化学株式会社 | 疾患鑑別支援装置及びコンピュータプログラム |
| TWI607739B (zh) * | 2016-05-27 | 2017-12-11 | 許百靈 | Ｓｐｅｃｔ多巴胺顯像定量分析技術與在腦多巴胺評估的用途 |
| GB201621698D0 (en) * | 2016-12-20 | 2017-02-01 | Ge Healthcare Ltd (Ip) And Stichting Vumc And Acad Medical Center | Differential Diagnosis |
| JP6995642B2 (ja) * | 2018-01-19 | 2022-01-14 | 日本メジフィジックス株式会社 | 画像処理装置、画像処理方法およびプログラム |
| TWI686178B (zh) | 2019-10-09 | 2020-03-01 | 中原大學 | 自動化定位核子醫學腦部影像紋狀體與計算紋狀體專一性攝取率的方法與系統 |
| WO2021102323A1 (en) * | 2019-11-21 | 2021-05-27 | Likeminds, Inc. | Pharmaceutical packaging units and methods for concomitant administration of radiotracers |
| MX2023010566A (es) | 2021-03-22 | 2023-09-21 | Neurocrine Biosciences Inc | Inhibidores de proteina transportadora vesicular monoaminotransportadora-2 (vmat2) y metodos de uso. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009040727A2 (en) * | 2007-09-26 | 2009-04-02 | Philips Intellectual Property & Standards Gmbh | Method of differentially diagnosing different types of dementia |
| EP2211911A4 (en) * | 2007-10-31 | 2012-11-14 | Alseres Pharmaceuticals Inc | METHOD FOR DIAGNOSIS AND MONITORING OF THE TREATMENT OF LEWY BODILY DAMAGE BY EVALUATING THE DOPAMIN TRANSPORTER MIRROR |
| US8084018B2 (en) * | 2007-10-31 | 2011-12-27 | Alseres Pharmaceuticals, Inc. | Methods for imaging dopamine transporter level |
-
2013
- 2013-07-25 GB GBGB1313291.5A patent/GB201313291D0/en not_active Ceased
-
2014
- 2014-07-25 KR KR1020167001611A patent/KR102340504B1/ko active IP Right Grant
- 2014-07-25 EP EP14742544.1A patent/EP3024501B1/en active Active
- 2014-07-25 DK DK14742544.1T patent/DK3024501T3/da active
- 2014-07-25 ES ES14742544T patent/ES2722973T3/es active Active
- 2014-07-25 RU RU2015155792A patent/RU2015155792A/ru unknown
- 2014-07-25 CA CA2916125A patent/CA2916125A1/en not_active Abandoned
- 2014-07-25 MX MX2016001012A patent/MX2016001012A/es unknown
- 2014-07-25 JP JP2016528546A patent/JP6590801B2/ja active Active
- 2014-07-25 WO PCT/EP2014/066042 patent/WO2015011267A1/en active Application Filing
- 2014-07-25 SG SG11201600571RA patent/SG11201600571RA/en unknown
- 2014-07-25 BR BR112016001316-6A patent/BR112016001316B1/pt active IP Right Grant
- 2014-07-25 AU AU2014294983A patent/AU2014294983B2/en active Active
- 2014-07-25 CN CN201480041743.1A patent/CN105392500B/zh active Active
- 2014-07-25 US US14/907,428 patent/US11051777B2/en active Active
-
2015
- 2015-12-28 IL IL243383A patent/IL243383B/en active IP Right Grant
-
2016
- 2016-08-30 HK HK16110276.6A patent/HK1222118A1/zh unknown
-
2019
- 2019-10-23 AU AU2019253837A patent/AU2019253837B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN105392500A (zh) | 2016-03-09 |
| US20160183897A1 (en) | 2016-06-30 |
| HK1222118A1 (zh) | 2017-06-23 |
| RU2015155792A (ru) | 2017-08-30 |
| KR20160037168A (ko) | 2016-04-05 |
| SG11201600571RA (en) | 2016-02-26 |
| RU2015155792A3 (es) | 2018-05-23 |
| BR112016001316B1 (pt) | 2021-04-06 |
| JP2016531903A (ja) | 2016-10-13 |
| GB201313291D0 (en) | 2013-09-11 |
| WO2015011267A1 (en) | 2015-01-29 |
| MX2016001012A (es) | 2016-05-09 |
| AU2019253837B2 (en) | 2021-11-25 |
| DK3024501T3 (da) | 2019-05-06 |
| AU2014294983B2 (en) | 2019-10-24 |
| JP6590801B2 (ja) | 2019-10-16 |
| CA2916125A1 (en) | 2015-01-29 |
| AU2019253837A1 (en) | 2019-11-14 |
| CN105392500B (zh) | 2023-08-18 |
| EP3024501A1 (en) | 2016-06-01 |
| AU2014294983A1 (en) | 2016-01-21 |
| EP3024501B1 (en) | 2019-03-27 |
| US11051777B2 (en) | 2021-07-06 |
| IL243383B (en) | 2018-07-31 |
| KR102340504B1 (ko) | 2021-12-20 |
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