AR092423A1 - Metodo de diagnostico y tratamiento del cancer dirigido a las moleculas expresadas en celulas madre cancerosas - Google Patents

Metodo de diagnostico y tratamiento del cancer dirigido a las moleculas expresadas en celulas madre cancerosas

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Publication number
AR092423A1
AR092423A1 ARP130103126A ARP130103126A AR092423A1 AR 092423 A1 AR092423 A1 AR 092423A1 AR P130103126 A ARP130103126 A AR P130103126A AR P130103126 A ARP130103126 A AR P130103126A AR 092423 A1 AR092423 A1 AR 092423A1
Authority
AR
Argentina
Prior art keywords
cancer
diagnosis
treatment
cancerosa
molecules expressed
Prior art date
Application number
ARP130103126A
Other languages
English (en)
Inventor
Kagamu Hiroshi
Hayashi Takashi
Narita Ichiei
Goto Yoshihiro
Original Assignee
Univ Niigata
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Niigata, Otsuka Pharma Co Ltd filed Critical Univ Niigata
Publication of AR092423A1 publication Critical patent/AR092423A1/es

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001154Enzymes
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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Abstract

La presente brinda un método para determinar la malignidad del cáncer, un método de diagnóstico del cáncer, un método para determinar el pronóstico, una vacuna para el tratamiento del cáncer y una vacuna para suprimir la metástasis del cáncer. Específicamente, se brinda un método de evaluación de la malignidad del cáncer, que comprende la etapa de medir el nivel de expresión en un tejido canceroso del polipéptido 3 con caja DEAD de ARN helicasas dependientes del ATP, ubicado en el cromosoma X (DDX3X), y la etapa de evaluar la malignidad del tejido canceroso utilizando el nivel de expresión de DDX3X.
ARP130103126A 2012-09-04 2013-09-03 Metodo de diagnostico y tratamiento del cancer dirigido a las moleculas expresadas en celulas madre cancerosas AR092423A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2012193757 2012-09-04

Publications (1)

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AR092423A1 true AR092423A1 (es) 2015-04-22

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ARP130103126A AR092423A1 (es) 2012-09-04 2013-09-03 Metodo de diagnostico y tratamiento del cancer dirigido a las moleculas expresadas en celulas madre cancerosas

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US (1) US20150297694A1 (es)
EP (1) EP2893352A2 (es)
JP (1) JP2015529825A (es)
KR (1) KR20150046787A (es)
CN (1) CN104769431A (es)
AR (1) AR092423A1 (es)
AU (1) AU2013313974A1 (es)
BR (1) BR112015004653A2 (es)
CA (1) CA2883577A1 (es)
EA (1) EA201590495A1 (es)
IL (1) IL237411A0 (es)
IN (1) IN2015DN01646A (es)
MX (1) MX2015002749A (es)
PH (1) PH12015500388A1 (es)
SG (1) SG11201501394SA (es)
TW (1) TW201413245A (es)
WO (1) WO2014038682A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017153952A1 (en) * 2016-03-10 2017-09-14 Glaxosmithkline Intellectual Property Development Limited 5-sulfamoyl-2-hydroxybenzamide derivatives
ITUA20161994A1 (it) * 2016-03-24 2017-09-24 Azienda Ospedaliera Univ Senese Uso degli inibitori ddx3 come agenti anti-iperproliferativi
US10738363B2 (en) 2016-08-31 2020-08-11 National Central University Analyzer and analytical method for predicting prognosis of cancer radiotherapy
TWI614629B (zh) * 2016-08-31 2018-02-11 National Central University 預測癌症放射線治療之預後的分析器及方法
WO2018147291A1 (en) * 2017-02-07 2018-08-16 Saitama Medical University Immunological biomarker for predicting clinical effect of cancer immunotherapy

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005005601A2 (en) * 2003-06-09 2005-01-20 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
CN1852974A (zh) * 2003-06-09 2006-10-25 密歇根大学董事会 用于治疗和诊断癌症的组合物和方法
JP5802872B2 (ja) * 2008-09-23 2015-11-04 ザ ジョンズ ホプキンズ ユニヴァーシティー 縮合ジイミダゾジアゼピン化合物並びにその使用及び製造方法
US20120202814A1 (en) * 2009-10-02 2012-08-09 Università Degli Studi Di Siena Compounds with ddx3 inhibitory activity and uses thereof

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Publication number Publication date
CA2883577A1 (en) 2014-03-13
BR112015004653A2 (pt) 2017-07-04
SG11201501394SA (en) 2015-03-30
IN2015DN01646A (es) 2015-07-03
IL237411A0 (en) 2015-04-30
KR20150046787A (ko) 2015-04-30
JP2015529825A (ja) 2015-10-08
WO2014038682A2 (en) 2014-03-13
PH12015500388A1 (en) 2015-04-27
US20150297694A1 (en) 2015-10-22
EP2893352A2 (en) 2015-07-15
EA201590495A1 (ru) 2015-07-30
TW201413245A (zh) 2014-04-01
CN104769431A (zh) 2015-07-08
AU2013313974A1 (en) 2015-03-12
MX2015002749A (es) 2015-09-25
WO2014038682A3 (en) 2014-05-15

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