AR092423A1 - Metodo de diagnostico y tratamiento del cancer dirigido a las moleculas expresadas en celulas madre cancerosas - Google Patents
Metodo de diagnostico y tratamiento del cancer dirigido a las moleculas expresadas en celulas madre cancerosasInfo
- Publication number
- AR092423A1 AR092423A1 ARP130103126A ARP130103126A AR092423A1 AR 092423 A1 AR092423 A1 AR 092423A1 AR P130103126 A ARP130103126 A AR P130103126A AR P130103126 A ARP130103126 A AR P130103126A AR 092423 A1 AR092423 A1 AR 092423A1
- Authority
- AR
- Argentina
- Prior art keywords
- cancer
- diagnosis
- treatment
- cancerosa
- molecules expressed
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 9
- 201000011510 cancer Diseases 0.000 title abstract 9
- 238000000034 method Methods 0.000 title abstract 5
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 210000000130 stem cell Anatomy 0.000 title 1
- 230000036210 malignancy Effects 0.000 abstract 3
- 102100033391 ATP-dependent RNA helicase DDX3X Human genes 0.000 abstract 2
- 101000870662 Homo sapiens ATP-dependent RNA helicase DDX3X Proteins 0.000 abstract 2
- 210000001519 tissue Anatomy 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 206010027476 Metastases Diseases 0.000 abstract 1
- 108060004795 Methyltransferase Proteins 0.000 abstract 1
- 210000001766 X chromosome Anatomy 0.000 abstract 1
- 230000009401 metastasis Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
Classifications
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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- G—PHYSICS
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/4164—1,3-Diazoles
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/57—Skin; melanoma
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
- C12Y306/04—Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
- C12Y306/04013—RNA helicase (3.6.4.13)
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
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- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
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- Mycology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
Abstract
La presente brinda un método para determinar la malignidad del cáncer, un método de diagnóstico del cáncer, un método para determinar el pronóstico, una vacuna para el tratamiento del cáncer y una vacuna para suprimir la metástasis del cáncer. Específicamente, se brinda un método de evaluación de la malignidad del cáncer, que comprende la etapa de medir el nivel de expresión en un tejido canceroso del polipéptido 3 con caja DEAD de ARN helicasas dependientes del ATP, ubicado en el cromosoma X (DDX3X), y la etapa de evaluar la malignidad del tejido canceroso utilizando el nivel de expresión de DDX3X.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012193757 | 2012-09-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR092423A1 true AR092423A1 (es) | 2015-04-22 |
Family
ID=49447765
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP130103126A AR092423A1 (es) | 2012-09-04 | 2013-09-03 | Metodo de diagnostico y tratamiento del cancer dirigido a las moleculas expresadas en celulas madre cancerosas |
Country Status (17)
Country | Link |
---|---|
US (1) | US20150297694A1 (es) |
EP (1) | EP2893352A2 (es) |
JP (1) | JP2015529825A (es) |
KR (1) | KR20150046787A (es) |
CN (1) | CN104769431A (es) |
AR (1) | AR092423A1 (es) |
AU (1) | AU2013313974A1 (es) |
BR (1) | BR112015004653A2 (es) |
CA (1) | CA2883577A1 (es) |
EA (1) | EA201590495A1 (es) |
IL (1) | IL237411A0 (es) |
IN (1) | IN2015DN01646A (es) |
MX (1) | MX2015002749A (es) |
PH (1) | PH12015500388A1 (es) |
SG (1) | SG11201501394SA (es) |
TW (1) | TW201413245A (es) |
WO (1) | WO2014038682A2 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017153952A1 (en) * | 2016-03-10 | 2017-09-14 | Glaxosmithkline Intellectual Property Development Limited | 5-sulfamoyl-2-hydroxybenzamide derivatives |
ITUA20161994A1 (it) * | 2016-03-24 | 2017-09-24 | Azienda Ospedaliera Univ Senese | Uso degli inibitori ddx3 come agenti anti-iperproliferativi |
US10738363B2 (en) | 2016-08-31 | 2020-08-11 | National Central University | Analyzer and analytical method for predicting prognosis of cancer radiotherapy |
TWI614629B (zh) * | 2016-08-31 | 2018-02-11 | National Central University | 預測癌症放射線治療之預後的分析器及方法 |
WO2018147291A1 (en) * | 2017-02-07 | 2018-08-16 | Saitama Medical University | Immunological biomarker for predicting clinical effect of cancer immunotherapy |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005005601A2 (en) * | 2003-06-09 | 2005-01-20 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
CN1852974A (zh) * | 2003-06-09 | 2006-10-25 | 密歇根大学董事会 | 用于治疗和诊断癌症的组合物和方法 |
JP5802872B2 (ja) * | 2008-09-23 | 2015-11-04 | ザ ジョンズ ホプキンズ ユニヴァーシティー | 縮合ジイミダゾジアゼピン化合物並びにその使用及び製造方法 |
US20120202814A1 (en) * | 2009-10-02 | 2012-08-09 | Università Degli Studi Di Siena | Compounds with ddx3 inhibitory activity and uses thereof |
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2013
- 2013-09-03 TW TW102131647A patent/TW201413245A/zh unknown
- 2013-09-03 WO PCT/JP2013/074172 patent/WO2014038682A2/en active Application Filing
- 2013-09-03 KR KR20157008399A patent/KR20150046787A/ko not_active Application Discontinuation
- 2013-09-03 AU AU2013313974A patent/AU2013313974A1/en not_active Abandoned
- 2013-09-03 BR BR112015004653A patent/BR112015004653A2/pt not_active IP Right Cessation
- 2013-09-03 JP JP2015529319A patent/JP2015529825A/ja active Pending
- 2013-09-03 CN CN201380057658.XA patent/CN104769431A/zh active Pending
- 2013-09-03 CA CA2883577A patent/CA2883577A1/en not_active Abandoned
- 2013-09-03 MX MX2015002749A patent/MX2015002749A/es unknown
- 2013-09-03 AR ARP130103126A patent/AR092423A1/es unknown
- 2013-09-03 EP EP13779641.3A patent/EP2893352A2/en not_active Withdrawn
- 2013-09-03 SG SG11201501394SA patent/SG11201501394SA/en unknown
- 2013-09-03 EA EA201590495A patent/EA201590495A1/ru unknown
- 2013-09-03 IN IN1646DEN2015 patent/IN2015DN01646A/en unknown
- 2013-09-03 US US14/423,929 patent/US20150297694A1/en not_active Abandoned
-
2015
- 2015-02-23 PH PH12015500388A patent/PH12015500388A1/en unknown
- 2015-02-25 IL IL237411A patent/IL237411A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2883577A1 (en) | 2014-03-13 |
BR112015004653A2 (pt) | 2017-07-04 |
SG11201501394SA (en) | 2015-03-30 |
IN2015DN01646A (es) | 2015-07-03 |
IL237411A0 (en) | 2015-04-30 |
KR20150046787A (ko) | 2015-04-30 |
JP2015529825A (ja) | 2015-10-08 |
WO2014038682A2 (en) | 2014-03-13 |
PH12015500388A1 (en) | 2015-04-27 |
US20150297694A1 (en) | 2015-10-22 |
EP2893352A2 (en) | 2015-07-15 |
EA201590495A1 (ru) | 2015-07-30 |
TW201413245A (zh) | 2014-04-01 |
CN104769431A (zh) | 2015-07-08 |
AU2013313974A1 (en) | 2015-03-12 |
MX2015002749A (es) | 2015-09-25 |
WO2014038682A3 (en) | 2014-05-15 |
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