KR102340504B1 - 신경계 질환의 영상화 - Google Patents

신경계 질환의 영상화 Download PDF

Info

Publication number
KR102340504B1
KR102340504B1 KR1020167001611A KR20167001611A KR102340504B1 KR 102340504 B1 KR102340504 B1 KR 102340504B1 KR 1020167001611 A KR1020167001611 A KR 1020167001611A KR 20167001611 A KR20167001611 A KR 20167001611A KR 102340504 B1 KR102340504 B1 KR 102340504B1
Authority
KR
South Korea
Prior art keywords
imaging
ratio
radiopharmaceutical
normal
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020167001611A
Other languages
English (en)
Korean (ko)
Other versions
KR20160037168A (ko
Inventor
마크 조셉 로저
잔 울버
Original Assignee
지이 헬쓰케어 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 지이 헬쓰케어 리미티드 filed Critical 지이 헬쓰케어 리미티드
Publication of KR20160037168A publication Critical patent/KR20160037168A/ko
Application granted granted Critical
Publication of KR102340504B1 publication Critical patent/KR102340504B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/48—Diagnostic techniques
    • A61B6/481—Diagnostic techniques involving the use of contrast agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/501—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of the head, e.g. neuroimaging or craniography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5217—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data extracting a diagnostic or physiological parameter from medical diagnostic data
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Neurosurgery (AREA)
  • Dentistry (AREA)
  • Neurology (AREA)
  • Physiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nuclear Medicine (AREA)
  • Pulmonology (AREA)
  • Theoretical Computer Science (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Primary Health Care (AREA)
KR1020167001611A 2013-07-25 2014-07-25 신경계 질환의 영상화 Active KR102340504B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1313291.5A GB201313291D0 (en) 2013-07-25 2013-07-25 Imaging neurological disease
GB1313291.5 2013-07-25
PCT/EP2014/066042 WO2015011267A1 (en) 2013-07-25 2014-07-25 Imaging neurological disease

Publications (2)

Publication Number Publication Date
KR20160037168A KR20160037168A (ko) 2016-04-05
KR102340504B1 true KR102340504B1 (ko) 2021-12-20

Family

ID=49166921

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020167001611A Active KR102340504B1 (ko) 2013-07-25 2014-07-25 신경계 질환의 영상화

Country Status (16)

Country Link
US (1) US11051777B2 (enExample)
EP (1) EP3024501B1 (enExample)
JP (1) JP6590801B2 (enExample)
KR (1) KR102340504B1 (enExample)
CN (1) CN105392500B (enExample)
AU (2) AU2014294983B2 (enExample)
BR (1) BR112016001316B1 (enExample)
CA (1) CA2916125A1 (enExample)
DK (1) DK3024501T3 (enExample)
ES (1) ES2722973T3 (enExample)
GB (1) GB201313291D0 (enExample)
IL (1) IL243383B (enExample)
MX (1) MX2016001012A (enExample)
RU (1) RU2015155792A (enExample)
SG (1) SG11201600571RA (enExample)
WO (1) WO2015011267A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104720840A (zh) * 2015-02-11 2015-06-24 清华大学深圳研究生院 基于多巴胺转运体显像特异性摄取比的半自动量化方法
TWI587841B (zh) * 2015-03-06 2017-06-21 國立陽明大學 定量分析核子醫學腦部影像的系統及方法
US20180000440A1 (en) * 2015-03-24 2018-01-04 Nihon Medi-Physics Co., Ltd. Image processing apparatus, image processing method, and program
KR101720288B1 (ko) 2016-05-11 2017-03-28 (주)바이오액츠 뇌 영상용 염료 및 이의 제조방법
JP6549521B2 (ja) * 2016-05-25 2019-07-24 富士フイルム富山化学株式会社 疾患鑑別支援装置及びコンピュータプログラム
TWI607739B (zh) * 2016-05-27 2017-12-11 許百靈 Ｓｐｅｃｔ多巴胺顯像定量分析技術與在腦多巴胺評估的用途
GB201621698D0 (en) * 2016-12-20 2017-02-01 Ge Healthcare Ltd (Ip) And Stichting Vumc And Acad Medical Center Differential Diagnosis
JP6995642B2 (ja) * 2018-01-19 2022-01-14 日本メジフィジックス株式会社 画像処理装置、画像処理方法およびプログラム
TWI686178B (zh) * 2019-10-09 2020-03-01 中原大學 自動化定位核子醫學腦部影像紋狀體與計算紋狀體專一性攝取率的方法與系統
US20230001026A1 (en) * 2019-11-21 2023-01-05 Likeminds, Inc. Pharmaceutical packaging units and methods for concomitant administration of radiotracers
AR125188A1 (es) 2021-03-22 2023-06-21 Neurocrine Biosciences Inc Inhibidores del vmat2 y métodos de uso
CN119599879B (zh) * 2024-11-06 2025-10-24 复旦大学附属华山医院 一种基于深度学习的pet图像跨膜态合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009040727A2 (en) * 2007-09-26 2009-04-02 Philips Intellectual Property & Standards Gmbh Method of differentially diagnosing different types of dementia
US8084018B2 (en) * 2007-10-31 2011-12-27 Alseres Pharmaceuticals, Inc. Methods for imaging dopamine transporter level
US20100312105A1 (en) * 2007-10-31 2010-12-09 Alseres Pharmaceuticals, Inc. Methods for diagnosing and monitoring treatment of lewy body dementia by assessing dopamine transporter level

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
J P SEIBYL 외. Annals of Neurology. Vol. 38(4), pp. 589-598
MEI-CHUN HSIAO 외.Schizophrenia Research. Vol. 65(1), pp.39-46
REGINA KATZENSCHNAGER 외. Annals of Neurology. Vol. 53(4), pp.489-496

Also Published As

Publication number Publication date
CN105392500B (zh) 2023-08-18
WO2015011267A1 (en) 2015-01-29
IL243383B (en) 2018-07-31
RU2015155792A3 (enExample) 2018-05-23
CA2916125A1 (en) 2015-01-29
US11051777B2 (en) 2021-07-06
GB201313291D0 (en) 2013-09-11
AU2014294983A1 (en) 2016-01-21
RU2015155792A (ru) 2017-08-30
JP6590801B2 (ja) 2019-10-16
HK1222118A1 (zh) 2017-06-23
ES2722973T3 (es) 2019-08-20
EP3024501A1 (en) 2016-06-01
KR20160037168A (ko) 2016-04-05
EP3024501B1 (en) 2019-03-27
DK3024501T3 (da) 2019-05-06
BR112016001316B1 (pt) 2021-04-06
US20160183897A1 (en) 2016-06-30
SG11201600571RA (en) 2016-02-26
JP2016531903A (ja) 2016-10-13
AU2014294983B2 (en) 2019-10-24
AU2019253837A1 (en) 2019-11-14
AU2019253837B2 (en) 2021-11-25
CN105392500A (zh) 2016-03-09
MX2016001012A (es) 2016-05-09

Similar Documents

Publication Publication Date Title
KR102340504B1 (ko) 신경계 질환의 영상화
Guedj et al. EANM procedure guidelines for brain PET imaging using [18F] FDG, version 3
Villemagne et al. In vivo evaluation of a novel tau imaging tracer for Alzheimer’s disease
Politis et al. Positron emission tomography imaging in neurological disorders
Park et al. 11C-PBR28 imaging in multiple sclerosis patients and healthy controls: test-retest reproducibility and focal visualization of active white matter areas
Riccardi et al. Amphetamine-induced displacement of [18F] fallypride in striatum and extrastriatal regions in humans
Henry et al. In vivo cerebral metabolism and central benzodiazepine‐receptor binding in temporal lobe epilepsy
US10650519B2 (en) Voxel-based methods for assessing subjects using magnetic resonance imaging
Masterman et al. Sensitivity, specificity, and positive predictive value of technetium 99-HMPAO SPECT in discriminating Alzheimer's disease from other dementias
Nocker et al. Progression of dopamine transporter decline in patients with the Parkinson variant of multiple system atrophy: a voxel-based analysis of [123I] β-CIT SPECT
Koeppe et al. Differentiating Alzheimer’s disease from dementia with Lewy bodies and Parkinson’s disease with (+)-[11C] dihydrotetrabenazine positron emission tomography
Henderson The diagnosis and evaluation of dementia and mild cognitive impairment with emphasis on SPECT perfusion neuroimaging
Hsiao et al. Comparison of 99mTc-TRODAT-1 SPECT and 18 F-AV-133 PET imaging in healthy controls and Parkinson’s disease patients
Molina et al. Prefrontal atrophy in first episodes of schizophrenia associated with limbic metabolic hyperactivity
JP2014148529A (ja) ドーパミン輸送体レベルを造影するための方法
JP2011502966A5 (enExample)
JP2011502966A (ja) ドーパミントランスポーターレベルを評価することによるレビー小体型認知症の診断およびレビー小体型認知症の処置のモニタリングのための方法
Romano et al. Florbetapir F 18 for brain imaging of beta-amyloid plaques
Varrone et al. Molecular imaging of neuroinflammation in Alzheimer’s disease
Booij et al. Imaging of striatal dopamine transporters in rat brain with single pinhole SPECT and co-aligned MRI is highly reproducible
Edison et al. Strategies for the generation of parametric images of [11C] PIB with plasma input functions considering discriminations and reproducibility
Huang et al. Chronic manganism: a long-term follow-up study with a new dopamine terminal biomarker of 18F-FP-(+)-DTBZ (18F-AV-133) brain PET scan
HK1222118B (zh) 成像神经学疾病
Niethammer et al. PET and SPECT Imaging in Atypical Parkinsonian Syndromes
Khattar et al. Optimized reference region and the effect on test-retest reliability and detection of Parkinson’s disease with [11C] UCB-J

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20160120

Patent event code: PA01051R01D

Comment text: International Patent Application

AMND Amendment
PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20190625

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20200810

Patent event code: PE09021S01D

AMND Amendment
E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20210222

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20200810

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

X091 Application refused [patent]
AMND Amendment
PX0901 Re-examination

Patent event code: PX09011S01I

Patent event date: 20210222

Comment text: Decision to Refuse Application

Patent event code: PX09012R01I

Patent event date: 20201012

Comment text: Amendment to Specification, etc.

Patent event code: PX09012R01I

Patent event date: 20160226

Comment text: Amendment to Specification, etc.

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20210526

Patent event code: PE09021S01D

AMND Amendment
PX0701 Decision of registration after re-examination

Patent event date: 20211123

Comment text: Decision to Grant Registration

Patent event code: PX07013S01D

Patent event date: 20210721

Comment text: Amendment to Specification, etc.

Patent event code: PX07012R01I

Patent event date: 20210426

Comment text: Amendment to Specification, etc.

Patent event code: PX07012R01I

Patent event date: 20210222

Comment text: Decision to Refuse Application

Patent event code: PX07011S01I

Patent event date: 20201012

Comment text: Amendment to Specification, etc.

Patent event code: PX07012R01I

Patent event date: 20160226

Comment text: Amendment to Specification, etc.

Patent event code: PX07012R01I

X701 Decision to grant (after re-examination)
GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20211214

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20211215

End annual number: 3

Start annual number: 1

PG1601 Publication of registration