JP2016531903A5 - - Google Patents
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- JP2016531903A5 JP2016531903A5 JP2016528546A JP2016528546A JP2016531903A5 JP 2016531903 A5 JP2016531903 A5 JP 2016531903A5 JP 2016528546 A JP2016528546 A JP 2016528546A JP 2016528546 A JP2016528546 A JP 2016528546A JP 2016531903 A5 JP2016531903 A5 JP 2016531903A5
- Authority
- JP
- Japan
- Prior art keywords
- ratio
- iii
- imaging
- radiopharmaceutical
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000003384 imaging method Methods 0.000 claims description 13
- 238000002405 diagnostic procedure Methods 0.000 claims description 8
- 210000001577 neostriatum Anatomy 0.000 claims description 7
- 208000012902 Nervous system disease Diseases 0.000 claims description 6
- 208000025966 Neurological disease Diseases 0.000 claims description 6
- 238000003745 diagnosis Methods 0.000 claims description 3
- 208000018737 Parkinson disease Diseases 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 17
- 229940121896 radiopharmaceutical Drugs 0.000 claims 9
- 239000012217 radiopharmaceutical Substances 0.000 claims 9
- 230000002799 radiopharmaceutical effect Effects 0.000 claims 9
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical group NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 claims 6
- 238000012544 monitoring process Methods 0.000 claims 5
- 238000010187 selection method Methods 0.000 claims 4
- 210000001159 caudate nucleus Anatomy 0.000 claims 3
- 229960003638 dopamine Drugs 0.000 claims 3
- 210000002637 putamen Anatomy 0.000 claims 3
- 102000006441 Dopamine Plasma Membrane Transport Proteins Human genes 0.000 claims 2
- 108010044266 Dopamine Plasma Membrane Transport Proteins Proteins 0.000 claims 2
- 210000004556 brain Anatomy 0.000 claims 2
- 210000004720 cerebrum Anatomy 0.000 claims 2
- 102100038238 Aromatic-L-amino-acid decarboxylase Human genes 0.000 claims 1
- 208000009829 Lewy Body Disease Diseases 0.000 claims 1
- 201000002832 Lewy body dementia Diseases 0.000 claims 1
- 206010034010 Parkinsonism Diseases 0.000 claims 1
- 108010035075 Tyrosine decarboxylase Proteins 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000011156 evaluation Methods 0.000 claims 1
- GTQLIPQFXVKRKJ-HYRAKNMCSA-N methyl (1s,3s,4s,5r)-3-(4-fluorophenyl)-8-[(e)-3-iodanylprop-2-enyl]-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1([C@H]2C[C@@H]3CC[C@@H](N3C\C=C\[123I])[C@H]2C(=O)OC)=CC=C(F)C=C1 GTQLIPQFXVKRKJ-HYRAKNMCSA-N 0.000 claims 1
- XLRPYZSEQKXZAA-OCAPTIKFSA-N tropane Chemical compound C1CC[C@H]2CC[C@@H]1N2C XLRPYZSEQKXZAA-OCAPTIKFSA-N 0.000 claims 1
- 229930004006 tropane Natural products 0.000 claims 1
- 230000000926 neurological effect Effects 0.000 description 3
- 206010068100 Vascular parkinsonism Diseases 0.000 description 1
- VREFGVBLTWBCJP-UHFFFAOYSA-N alprazolam Chemical compound C12=CC(Cl)=CC=C2N2C(C)=NN=C2CN=C1C1=CC=CC=C1 VREFGVBLTWBCJP-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1313291.5A GB201313291D0 (en) | 2013-07-25 | 2013-07-25 | Imaging neurological disease |
| GB1313291.5 | 2013-07-25 | ||
| PCT/EP2014/066042 WO2015011267A1 (en) | 2013-07-25 | 2014-07-25 | Imaging neurological disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016531903A JP2016531903A (ja) | 2016-10-13 |
| JP2016531903A5 true JP2016531903A5 (enExample) | 2019-01-17 |
| JP6590801B2 JP6590801B2 (ja) | 2019-10-16 |
Family
ID=49166921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016528546A Active JP6590801B2 (ja) | 2013-07-25 | 2014-07-25 | 神経学的疾患のイメージング |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US11051777B2 (enExample) |
| EP (1) | EP3024501B1 (enExample) |
| JP (1) | JP6590801B2 (enExample) |
| KR (1) | KR102340504B1 (enExample) |
| CN (1) | CN105392500B (enExample) |
| AU (2) | AU2014294983B2 (enExample) |
| BR (1) | BR112016001316B1 (enExample) |
| CA (1) | CA2916125A1 (enExample) |
| DK (1) | DK3024501T3 (enExample) |
| ES (1) | ES2722973T3 (enExample) |
| GB (1) | GB201313291D0 (enExample) |
| IL (1) | IL243383B (enExample) |
| MX (1) | MX2016001012A (enExample) |
| RU (1) | RU2015155792A (enExample) |
| SG (1) | SG11201600571RA (enExample) |
| WO (1) | WO2015011267A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104720840A (zh) * | 2015-02-11 | 2015-06-24 | 清华大学深圳研究生院 | 基于多巴胺转运体显像特异性摄取比的半自动量化方法 |
| TWI587841B (zh) * | 2015-03-06 | 2017-06-21 | 國立陽明大學 | 定量分析核子醫學腦部影像的系統及方法 |
| US20180000440A1 (en) * | 2015-03-24 | 2018-01-04 | Nihon Medi-Physics Co., Ltd. | Image processing apparatus, image processing method, and program |
| KR101720288B1 (ko) | 2016-05-11 | 2017-03-28 | (주)바이오액츠 | 뇌 영상용 염료 및 이의 제조방법 |
| JP6549521B2 (ja) * | 2016-05-25 | 2019-07-24 | 富士フイルム富山化学株式会社 | 疾患鑑別支援装置及びコンピュータプログラム |
| TWI607739B (zh) * | 2016-05-27 | 2017-12-11 | 許百靈 | Ｓｐｅｃｔ多巴胺顯像定量分析技術與在腦多巴胺評估的用途 |
| GB201621698D0 (en) * | 2016-12-20 | 2017-02-01 | Ge Healthcare Ltd (Ip) And Stichting Vumc And Acad Medical Center | Differential Diagnosis |
| JP6995642B2 (ja) * | 2018-01-19 | 2022-01-14 | 日本メジフィジックス株式会社 | 画像処理装置、画像処理方法およびプログラム |
| TWI686178B (zh) * | 2019-10-09 | 2020-03-01 | 中原大學 | 自動化定位核子醫學腦部影像紋狀體與計算紋狀體專一性攝取率的方法與系統 |
| US20230001026A1 (en) * | 2019-11-21 | 2023-01-05 | Likeminds, Inc. | Pharmaceutical packaging units and methods for concomitant administration of radiotracers |
| AR125188A1 (es) | 2021-03-22 | 2023-06-21 | Neurocrine Biosciences Inc | Inhibidores del vmat2 y métodos de uso |
| CN119599879B (zh) * | 2024-11-06 | 2025-10-24 | 复旦大学附属华山医院 | 一种基于深度学习的pet图像跨膜态合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009040727A2 (en) * | 2007-09-26 | 2009-04-02 | Philips Intellectual Property & Standards Gmbh | Method of differentially diagnosing different types of dementia |
| US8084018B2 (en) * | 2007-10-31 | 2011-12-27 | Alseres Pharmaceuticals, Inc. | Methods for imaging dopamine transporter level |
| US20100312105A1 (en) * | 2007-10-31 | 2010-12-09 | Alseres Pharmaceuticals, Inc. | Methods for diagnosing and monitoring treatment of lewy body dementia by assessing dopamine transporter level |
-
2013
- 2013-07-25 GB GBGB1313291.5A patent/GB201313291D0/en not_active Ceased
-
2014
- 2014-07-25 BR BR112016001316-6A patent/BR112016001316B1/pt active IP Right Grant
- 2014-07-25 CN CN201480041743.1A patent/CN105392500B/zh active Active
- 2014-07-25 WO PCT/EP2014/066042 patent/WO2015011267A1/en not_active Ceased
- 2014-07-25 DK DK14742544.1T patent/DK3024501T3/da active
- 2014-07-25 KR KR1020167001611A patent/KR102340504B1/ko active Active
- 2014-07-25 JP JP2016528546A patent/JP6590801B2/ja active Active
- 2014-07-25 RU RU2015155792A patent/RU2015155792A/ru unknown
- 2014-07-25 US US14/907,428 patent/US11051777B2/en active Active
- 2014-07-25 MX MX2016001012A patent/MX2016001012A/es unknown
- 2014-07-25 SG SG11201600571RA patent/SG11201600571RA/en unknown
- 2014-07-25 EP EP14742544.1A patent/EP3024501B1/en active Active
- 2014-07-25 CA CA2916125A patent/CA2916125A1/en not_active Abandoned
- 2014-07-25 AU AU2014294983A patent/AU2014294983B2/en active Active
- 2014-07-25 ES ES14742544T patent/ES2722973T3/es active Active
-
2015
- 2015-12-28 IL IL243383A patent/IL243383B/en active IP Right Grant
-
2019
- 2019-10-23 AU AU2019253837A patent/AU2019253837B2/en active Active
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