CN105381418A - 治疗桥本甲状腺炎的中药制剂 - Google Patents

治疗桥本甲状腺炎的中药制剂 Download PDF

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CN105381418A
CN105381418A CN201510986958.7A CN201510986958A CN105381418A CN 105381418 A CN105381418 A CN 105381418A CN 201510986958 A CN201510986958 A CN 201510986958A CN 105381418 A CN105381418 A CN 105381418A
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王璐
许璟
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Qingdao Changanda Pharmaceutical Co Ltd
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Abstract

本发明公开了一种治疗桥本甲状腺炎的中药制剂，由以下重量份的中药原料制成：红大戟33-46份，龙脷叶31-39份，生地25-36份，鹿茸22-29份，丹参18-27份，商陆12-27份，乌药8-16份，山奈5-12份，郁金6-15份，茯苓8-13份，旋覆花3-8份。本发明各种组分均为纯中药，诸药合用疏肝理气、健脾养血、活血化瘀、软坚散结，对甲状腺组织具有保护和修复作用，有效改善或缓解患者症状，有效率92.5％，达到治疗早期、不伴有甲状腺功能障碍的桥本甲状腺炎目的，无不良反应及毒副作用。

Description

治疗桥本甲状腺炎的中药制剂
技术领域
本发明涉及一种治疗桥本甲状腺炎的中药制剂。
背景技术
桥本甲状腺炎(HT)是一种临床上常见的自身免疫性甲状腺疾病，由于本病的组织学特征表现为弥漫性淋巴细胞浸润、纤维化、间质萎缩及腺泡细胞的嗜酸性改变，故也称为慢性淋巴细胞性甲状腺炎。本病好发于30～50岁女性，近年来其发病率呈逐渐增高的趋势。目前西医治疗本病多采取甲状腺激素替代疗法、免疫疗法、手术治疗等，疗效肯定，但不良反应多，且易复发。本发明制备得到的中药制剂治疗桥本甲状腺炎，取得了良好的效果。
发明内容
本发明所要解决的技术问题是：提供一种治疗效果好、有效率高、对人体无毒副作用的治疗桥本甲状腺炎的中药制剂。
为解决上述技术问题，本发明采用的技术方案是：
本发明提供的治疗桥本甲状腺炎的中药制剂，由以下重量份的中药原料制成：红大戟33-46份，龙脷叶31-39份，生地25-36份，鹿茸22-29份，丹参18-27份，商陆12-27份，乌药8-16份，山奈5-12份，郁金6-15份，茯苓8-13份，旋覆花3-8份。
优选的，本发明提供的中药由以下重量份的中药原料制成：红大戟40份，龙脷叶33份，生地30份，鹿茸26份，丹参21份，商陆17份，乌药11份，山奈8份，郁金11份，茯苓10份，旋覆花5份。
用法用量：将上述原料用温水浸泡10分钟后，用武火煮沸后再用文火煮30分钟，取药液150毫升，再加水二煎，将两次药液混合后过滤，分两次服用。每天两次，饭后服用。
疗程：15天为一疗程，需服用2-5疗程。
临床报告如下：1、一般资料100例患者中，女性41例，男性59例。
2、诊断标准(1)弥漫性质地坚硬的甲状腺肿。(2)TgAb(甲状腺球蛋白抗体)和TmAb(甲状腺微粒体抗体)显著增高或伴有FT4(血清游离甲状腺素)、FT3(血清游离三碘甲腺原氨酸)降低。(3)甲状腺细针病理穿刺检查。
3、治疗方法将本发明的中药用温水浸泡10分钟后，用武火煮沸后再用文火煮30分钟，取药液150毫升，再加水二煎，将两次药液混合后过滤，分两次服用。每天两次，饭后服用。
疗程：15天为一疗程，需服用2-5疗程。
4、治疗结果：4.1参照《中医病证诊断疗效标准》：治愈：临床症状消失，甲状腺无肿大，TgAb、TmAb、FT4、FT3水平正常；好转：临床症状明显减轻，甲状腺肿大缩小超过50％，TgAb、TmAb、FT4、FT3水平接近正常；有效：临床症状有所减轻，甲状腺肿大缩小，TgAb、TmAb、FT4、FT3水平改善；未愈：甲状腺肿缩小不明显或无缩小，TgAb、TmAb、FT4、FT3无变化或加重。4.2结果：100例患者中，治愈77例，好转11例，有效7例，总有效率为95％。
本发明的有益效果：
本发明各种组分均为纯中药，诸药合用疏肝理气、健脾养血、活血化瘀、软坚散结，对甲状腺组织具有保护和修复作用，有效改善或缓解患者症状，达到治疗早期、不伴有甲状腺功能障碍的桥本甲状腺炎目的，无不良反应及毒副作用。
具体实施方式
实施例1
本实施例提供的治疗桥本甲状腺炎的中药制剂，由以下重量份的中药原料制成：红大戟40份，龙脷叶33份，生地30份，鹿茸26份，丹参21份，商陆17份，乌药11份，山奈8份，郁金11份，茯苓10份，旋覆花5份。
典型病例：
1.孙某，女，57岁，双侧甲状腺II度肿大，质软，无触痛。舌淡红、苔薄腻，脉细。甲状腺B超：双侧甲状腺弥漫性增大。服用了本发明治疗桥本甲状腺炎的中药组合物，2个疗程后，甲状腺肿诸症均改善。复查甲状腺功能已恢复正常，TGAb及TPOAb有所下降。继续服用3个疗程，各指标恢复正常，病获痊愈。
2.唐某，男，63岁，甲状腺轻度弥漫肿大；服用本药2个疗程后，症状减轻，继续服药2个疗程，痊愈。

Claims (2)

1.一种治疗桥本甲状腺炎的中药制剂，其特征在于，由以下重量份的中药原料制成：红大戟33-46份，龙脷叶31-39份，生地25-36份，鹿茸22-29份，丹参18-27份，商陆12-27份，乌药8-16份，山奈5-12份，郁金6-15份，茯苓8-13份，旋覆花3-8份。
2.根据权利要求1所述的中药，其特征在于，由以下重量份的中药原料制成：红大戟40份，龙脷叶33份，生地30份，鹿茸26份，丹参21份，商陆17份，乌药11份，山奈8份，郁金11份，茯苓10份，旋覆花5份。
CN201510986958.7A 2015-12-26 2015-12-26 治疗桥本甲状腺炎的中药制剂 Pending CN105381418A (zh)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103041215A (zh) * 2013-01-05 2013-04-17 闫向东 一种治疗桥本甲状腺炎的中药组合物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103041215A (zh) * 2013-01-05 2013-04-17 闫向东 一种治疗桥本甲状腺炎的中药组合物

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Application publication date: 20160309