CN105381137B - Chinese medicine composition and preparation method thereof for treating bone and joint diseases - Google Patents
Chinese medicine composition and preparation method thereof for treating bone and joint diseases Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K36/74—Rubiaceae (Madder family)
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- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Abstract
The present invention provides a kind of Chinese medicine compositions and preparation method thereof for treating bone and joint diseases, belong to the field of Chinese medicines.The Chinese medicine includes following components: by weight, 5~20 parts of Radix Angelicae Sinensis, 5~20 parts of Rhizoma Chuanxiong, 6~18 parts of safflower, 3~12 parts of peach kernel, 8~30 parts of olibanum, 1~8 part of dragon's blood, 6~21 parts of catechu, 10~34 parts of borneol, 10~13 parts of raw madder, 4~10 parts of pilose antler, 2~5 parts of naze, 10~21 parts of lopseed, fragrant 0.5~1 part very little, 10~23 parts of the rhizome of davallia, 10~15 parts of rhizoma atractylodis, 10~30 parts of pyrolusite, 9~24 parts of dark plum, 4~11 parts of Caulis Spatholobi, 10~17 parts of cortex albiziae.The Chinese medicine can improve human body Bones and joints function, repair impaired Bones and joints, periosteum, tissue, improve the therapeutic effect to bone and joint diseases.
Description
Technical field
The present invention relates to Chinese medicine field of pharmaceutical technology, in particular to a kind of for treating the Chinese medicine of bone and joint diseases
Composition and preparation method thereof.
Background technique
Osteoarthropathy includes retrogression arthritis, hypertrophic arthritis, senescent arthritis, joint deformity etc., is one
Kind chronic joint diseases, are easy to cause articular cartilage degenerative disease and secondary osteoproliferation.Osteoarthropathy is that one kind causes to close
The person in middle and old age's common disease for saving pain and joint function disturbance, for example, spur, osteoproliferation, cervical spondylosis, chondromalacia patella, lumbar vertebrae
Disease belongs to the scope of osteoarthritis.Existing Chinese traditional treatment method mostly uses conservative treatment, for example, physical therapy, acupuncture, movement etc.
Method is aided with physical therapy again, can be relieved symptom and delays progression of the disease.But there is a problem of that curative effect is slow, cure rate is low.
Summary of the invention
The purpose of the present invention is to provide a kind of Chinese medicine compositions and preparation method thereof for treating bone and joint diseases, should
The advantages that Chinese medicine composition is cheap, easy to use, rapid-action.
The present invention is implemented as follows:
The present invention provides a kind of Chinese medicine compositions for treating bone and joint diseases, including following components: by weight,
5~20 parts of Radix Angelicae Sinensis, 5~20 parts of Rhizoma Chuanxiong, 6~18 parts of safflower, 3~12 parts of peach kernel, 8~30 parts of olibanum, dragon's blood 1~8
Part, 6~21 parts of catechu, 10~34 parts of borneol, 10~13 parts of raw madder, 4~10 parts of pilose antler, 2~5 parts of naze, lopseed 10~
21 parts, fragrant 0.5~1 part very little, 10~23 parts of the rhizome of davallia, 10~15 parts of rhizoma atractylodis, 10~30 parts of pyrolusite, 9~24 parts of dark plum, chicken blood
4~11 parts of rattan, 10~17 parts of cortex albiziae.
When the dry root for being classified as umbelliferae angelica, can enrich blood and invigorate blood circulation, can promoting menstruation, and can be active.
Rhizome of chuanxiong is irregular nodular pattern fist shape agglomerate, and surface yellowish-brown, coarse shrinkage has the wheel section of most parallel ridges,
There is the similar round stem trace of recess on top, has most small warty root traces on downside and wheel section.Matter is solid, is not easily broken, and section is yellowish-white
Color or lark, dissipate the grease chamber for having yellowish-brown, and forming layer is in wavy ring grain.Gas giving off a strong fragrance, it is bitter, pungent.
Safflower alias: red blue flower, thorn safflower belong to composite family, safflower plant, and dry tubular flower, orange red, floral tube is narrow
Carefully, sliver narrow line shape, anther yellow, is unified into pipe, is higher by except sliver, and there is column cap exposing in center.Has special fragrance, taste is micro-
It is bitter.
Peach kernel is the dry mature seed of rosaceous plant peach.It is harvested after fruit maturation, removes pulp and nucleocapsid, take out kind
Son dries.With promoting blood circulation, relax bowel and defecation, relieving cough and asthma effect.For amenorrhea and algomenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, pulmonary abscess acute appendicitis,
Injury from falling down, dry constipation of intestines, cough and asthma.
Olibanum is the resin of olive subject plant Boswellia carterii bark exudation.Surface yellow-white, it is translucent, there is yellowish-white toner
Then color burn is deposited at end long.Matter is crisp, heat softening.The plane of disruption has hyaloid or waxy gloss.Have special fragrance, mildly bitter flavor.
Dragon's blood, which is that the resin of babassu Sanguis Draxonis fruit exudation is processed, to be made.With promoting blood circulation analgesic therapy, removing blood stasis and hemostasis,
The effect of myogenic sore.For traumatic injury, trusted subordinate's stasis caused pain, traumatic hemorrhage, sore do not held back.
Catechu is the peeling branch, dry drying soft extracts of leguminous plant catechu.Winter harvests branch, does, and removes crust, is chopped to big
Block adds water to cook, and is concentrated, dry.With promoting blood circulation and stopping pain, the effect of hemostasia and promoting granulation, hygroscopic sore, clearing lung and eliminating phlegm.It is flutterred for falling
The pain of injury, traumatic hemorrhage, hematemesis and epistaxis, sore are not held back, eczema, wet sore, cough with lung heat.
Borneol through steam distillation and is recrystallized and is obtained by composite family Blumea balsamifera cauline leaf or lauraceae plant borneol camphor tree branches and leaves.Its
It can be used for closing card coma, for red eye, swell pain, sore throat aphtha is used for sore swell and ache curative, does not hold back after bursting.
Raw madder is is Rubia plants, and suitable for mesh internal haemorrhage, haematemesis, hemoptysis etc. caused by blood-heat bleeding, this product has
The function for dissolving stasis of stopping blooding, therefore stop blooding without staying the stasis of blood.
Pilose antler is deer is unossified and young horn with fine hair.Contain phosphatide, glycolipid, glue rouge, hormone, fatty acid, ammonia in pilose antler
The ingredients such as base acid, protein and calcium, phosphorus, magnesium, sodium, are used as tonic invigorator, effective in cure to weakness, neurasthenia etc..
Naze is to be processed by the scale and shell of pangolin, and taste is salty, have detumescence suppurations, scattered silt dredging collateral, promoting menstruation, it is lower it is newborn,
Invigorating blood circulation analgesia.
Lopseed is plant all herbal medicine, controls traumatic injury, sore, eczema, scabies.
Very little fragrant also known as Moschus, fragrant navel, musk deer navel perfume (or spice) are in the mature male body note capsule of animal in deer family woods musk deer, horse musk deer or former musk deer
Dry secretion, has the effect of blood circulation, swelling and pain relieving.
Rhizome of davallia epiphyte, rhizomes are used as medicine, can continues and hinders pain relieving, treat falling winks frustrates, injured bone.
Rhizoma atractylodis rhizomes is used as medicine, and has the benefits of turbid eliminating dampness, change, analgesic.
Pyrolusite is oxide-based mineral rutile race pyrolusite stone, main to contain manganese dioxide, after excavation, removes silt and miscellaneous
Matter is dried.It is used for traumatic injury, metal-inflicted wound carbuncle swells with stasis-dispelling and pain-killing, detumescence and promoting granulation.
Dark plum is the drying almost ripe fruit of rose department plant plum, and summer fruit harvests when closely mature, bored after low temperature drying
It is black to discoloration, it can be used for abnormal heat and quench one's thirst.
Caulis Spatholobi is the drying rattan of leguminous plant spatholobus suberectus.Autumn, the harvesting of two season of winter, branches and leaves are removed, slice dries.Tool
There is the effect of blood circulation promoting and enriching, rheumatic arthralgia, paralysis and numbness, blood deficiency chlorosis can be treated.
The dry bark of cortex albiziae leguminous plant silk tree.Summer, Qiu Erji are stripped, and are dried, and reason has activating blood circulation and reducing swelling, treat bruise
The benefits of grieved.
Pilose antler, Radix Angelicae Sinensis, Rhizoma Chuanxiong, safflower, peach kernel, raw madder, dragon's blood energy blood-nourishing are enriched blood, production of sperm marrow strengthening the bones and muscles, promote human body
The generation of bone growth and synovia can repair impaired cartilage, periosteum, prevent Bones and joints from continuing to be worn, this
Outside, also there is promoting blood circulation, dredge the blood vessel of pent-up, promote the supply of nutrition, put on flesh conducive to myogenic, joint is protected,
So being monarch drug in a prescription.Caulis Spatholobi, olibanum, cortex albiziae, rhizome of davallia promoting blood circulation, detumescence, analgesic, play the clinical symptoms of osteoarthropathy slow
Solution effect, reduces the pain of patient, improves the quality of living, so being ministerial drug.Dark plum, catechu, pyrolusite, rhizoma atractylodis treatment of arthritis and promoting collateral and channels,
Borneol removing dampness to stop itchin can prevent stimulation of the extraneous hygrothermal environment to Bones and joints, and sharp joint is restored, grown, so being adjutant.Thoroughly
Bone grass, very little fragrant, the current twelve channels and collaterals of naze, promote vim and vigour circulation, dredge the channels and collaterals of obstruction, give full play to the effect of drug, institute
Thinking makes medicine.In short, above-mentioned all the components interaction, occurs synergistic effect as an organic whole, integrates and play
The curative effect for treating bone and joint diseases.
Preferably, the Chinese medicine composition of the treatment bone and joint diseases is Oral preparation.
A kind of production method of the Chinese medicine composition of above-mentioned treatment bone and joint diseases, comprising the following steps: by all raw materials
Mixing, be milled to get.
Preferably, further include following components: by weight, 8~14 parts of monkshood, 10~12 parts of radix aconiti agrestis, vomiting nut 10~
23 parts.
Monkshood also known as be rhizome of Chinese monkshood perennial herb, gas is micro-, and acrid flavour, numb tongue are used for dispelling wind and eliminating dampness, antalgic.
Radix aconiti agrestis is the dried root of the ranunculaceae plant north rhizome of Chinese monkshood, and autumn cauline leaf is excavated when withered, removes fibrous root and silt, is done
It is dry.It can be used for wind-cold-dampness arthralgia, arthralgia, trusted subordinate's crymodynia, cold hernia is had a pain and narcotic analgesic.
Vomiting nut Loganiaceae, Logania arbor.It is used as medicine after seed is brewed, cold in nature, bitter has activating collaterals and eliminating stagnation, swelling and pain relieving
The benefits of.
Pilose antler, Radix Angelicae Sinensis, Rhizoma Chuanxiong, safflower, peach kernel, raw madder, dragon's blood are monarch drug in a prescription, repair impaired cartilage, periosteum, are conducive to life
Flesh is put on flesh.Caulis Spatholobi, olibanum, cortex albiziae, the rhizome of davallia are ministerial drug, and the clinical condition of bone and joint diseases is alleviated in promoting blood circulation, detumescence, analgesic
Shape.Dark plum, catechu, pyrolusite, rhizoma atractylodis, borneol, monkshood, radix aconiti agrestis, vomiting nut are adjutant, dispel the raw of bone joint pent-up
Gas, resistivity of the enhancing Bones and joints to extraneous warm and humid environment.Lopseed, very little fragrant, the current twelve channels and collaterals of naze, have it is deep,
The effect of transdermal, makes the through lesion of the effective component of drug, gives full play to the effect of drug, so to make medicine.Above-mentioned each medicinal material
Interaction, balances the efficacy of a drug of each medicinal material, synergistic effect occurs as a whole, integrate and play treatment bone and joint diseases
Curative effect.
Preferably, the Chinese medicine composition of the treatment bone and joint diseases is external preparation.
Preferably, further includes: excipient, it is preferable that the excipient includes honey and/or vaseline.
A kind of production method of the Chinese medicine composition of above-mentioned treatment bone and joint diseases includes the following steps:
Step 1): raw material is weighed according to the ratio for treating the Chinese medicine composition of bone and joint diseases, by raw material point
Be two parts of A, B, described A parts with described B parts of weight ratio 1:1~1:3；
Step 2): described A parts of each medicinal material is mixed, milling, obtains powder；
Step 3): described B parts of each medicinal material is mixed, and is decocted 20~50 minutes with water, filter and remove residue obtains filtrate；
Step 4): being added the powder in Xiang Suoshu filtrate, heating tanning is to dropping into a bead shape to get external preparation.
The production method takes each medicinal material of a Chinese medicine composition to be mixed first, and milling prepares powder, spare.Then,
Each medicinal material of a Chinese medicine composition is got again to be mixed, decocted with water, and the effective component in its medicinal material is made to dissolve out Yu Shuizhong, mistake
After filtering off slag, filtrate is collected.Using the filtrate of collection as infusion liquid, powder is added in filtrate, then is boiled.With filter
The gradually volatilization of moisture in liquid, the jelly in filtrate are gradually attached to powder, and with being constantly concentrated, viscosity gradually increases
Add, drops into a bead shape until being formed.
Traditional technology of boiling medicine directly decocts medicinal material, then removes filter residue, uses filtrate.It is some effective in drug
Ingredient is not easy to endure out, and the effective component in filtrate that this method obtains is less, and the utilization rate of medicinal material is caused 40%~50%
The waste of medicinal material.
In the present invention, powder made of Chinese medicine keeps pharmacological property, the drug effect of crude drug, decocts more convenient.Powder Chinese medicine
The partial size of material is small, and wherein effective component is easier to discharge when infusion, it is easier to decoct and dissolve out in decoction liquor.By Chinese medicine system
At powder, be finally used as medicine, so that the utilization rate of medicinal material improves, and be made in the Chinese medicine composition for the treatment of bone and joint diseases effectively
Component content is high.Powder, which is used directly, to be used as medicine, make finally treat bone and joint diseases Chinese medicine composition in medicinal ingredient more
It is abundant, it reduces since removal filter residue leads to the missing of medicinal ingredient.In addition, powder also acts as the effect of thickening, it is easy to form,
Reduce the dosage of other non-medicinal ingredients.
Compared to directly the powder made of medicinal material is decocted with water, it is used as decocting powder by the filtrate that medicinal material decocts
The liquid medium of material, the then effective component that is dissolved in filtrate, can fully phases between various effective components by boiling repeatedly
Interaction, can reconcile the pharmacological property of each medicinal material, make the pharmacological property milder of the Chinese medicine composition of the treatment bone and joint diseases finally prepared,
Irritation is small.
Preferably, in step 3), after mixing, before decoction, further includes: impregnate 3~10 minutes in water.Pass through immersion
Drug can be made sufficiently to infiltrate moisture, make the cell water swelling in medicinal material, in order to which effective component is dissolved in medicinal material tissue,
And then by diffusing into water.The protein in medicinal material tissue is avoided to agglomerate, form sediment further, it is also possible to play to a certain extent
Paste mixing improves the dissolution of effective component.
Preferably, in step 4), heating tanning specifically: boil 2 hours or more at 80~100 DEG C, then 45~
It is boiled 10~15 hours at 55 DEG C.High temperature boils first, medicinal material can be made sufficiently heated, the effective component in medicinal material makes medicinal material
In effective component Fast Stripping；Then low temperature boils, and avoid high temperature from decocting leads to being destroyed for effective component too long.
Preferably, after step 4), further includes: pharmaceutically acceptable excipient is added, carries out solid.
Beneficial effects of the present invention:
The present invention provides a kind of Chinese medicine compositions for treating bone and joint diseases, preparation and preparation method thereof.The Chinese medicine group
Object is closed according to traditional Chinese medical theory, carries out prescription in conjunction with osteoarthropathy pathogenesis, the drug of the treatment osteoarthropathy has promoting the circulation of qi
Promoting blood circulation, the effect of warming channel and expelling cold, treatment of arthritis and promoting collateral and channels, stasis-dispelling and pain-killing.Each raw material is natural plants, with expelling wind and clearing away cold, spasmolysis dredging collateral, promoting blood circulation
Change for the purpose of becoming silted up, at the same also warming kidney and enhancing yang, strengthen the body resistance to consolidate the constitution, achieve the effect that strengthen muscles and bones, treatment of arthritis disease.
Specific embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the invention.It is not specified in embodiment specific
Condition person carries out according to conventional conditions or manufacturer's recommended conditions.Reagents or instruments used without specified manufacturer is
The conventional products that can be obtained by commercially available purchase.
Embodiment 1
Present embodiments providing a kind of Chinese medicine composition for treating bone and joint diseases includes following components:
5 grams of Radix Angelicae Sinensis, 5 grams of Rhizoma Chuanxiong, 6 grams of safflower, 3 grams of peach kernel, 8 grams of olibanum, 1~8 gram of dragon's blood, 6 grams of catechu, 10 grams of borneol,
10 grams of raw madder, 4 grams of pilose antler, 2 grams of naze, 10 grams of lopseed, fragrant 0.5 gram very little, 10 grams of the rhizome of davallia, 10 grams of rhizoma atractylodis, pyrolusite 10
Gram, 9 grams of dark plum, 4 grams of Caulis Spatholobi, 10 grams of cortex albiziae.
The Chinese medicinal composition preparation of above-mentioned treatment bone and joint diseases is made by the following method:
Each raw material is weighed according to above-mentioned weight ratio, and each raw material is crushed with Universalpulverizer respectively, is then mixed, is ground
Mill be powder to get.
The Chinese medicine composition is endo-medicine, and above-mentioned powder can be taken after mixing it with water with yellow rice wine, and alcohol intolerance person can take after mixing it with hot water, often
Day twice, one time 6 grams.
Embodiment 2
Present embodiments providing a kind of Chinese medicine composition for treating bone and joint diseases includes following components:
10 grams of Radix Angelicae Sinensis, 10 grams of Rhizoma Chuanxiong, 10 grams of safflower, 6 grams of peach kernel, 10 grams of olibanum, 6 grams of dragon's blood, 6 grams of catechu, 10 grams of borneol,
10 grams of raw madder, 6 grams of pilose antler, 5 grams of naze, 10 grams of lopseed, fragrant 0.5 gram very little, 10 grams of the rhizome of davallia, 10 grams of rhizoma atractylodis, pyrolusite 10
Gram, 10 grams of dark plum, 10 grams of Caulis Spatholobi, 10 grams of cortex albiziae.
The Chinese medicinal composition preparation of above-mentioned treatment bone and joint diseases is made by the following method:
Each raw material is weighed according to above-mentioned weight ratio, each raw material is cut into broken section, and then broken section of each raw material is mixed, is ground to
Powder to get.The Chinese medicine composition is endo-medicine, and boiled water takes after mixing it with water, twice daily, one time 6 grams.
Embodiment 3
Present embodiments providing a kind of Chinese medicine composition for treating bone and joint diseases includes following components:
20 grams of Radix Angelicae Sinensis, 10 grams of Rhizoma Chuanxiong, 13 grams of safflower, 5 grams of peach kernel, 8 grams of olibanum, 8 grams of dragon's blood, 7 grams of catechu, 14 grams of borneol,
10 grams of raw madder, 6 grams of pilose antler, 3 grams of naze, 11 grams of lopseed, fragrant 0.6 gram very little, 12 grams of the rhizome of davallia, 14 grams of rhizoma atractylodis, pyrolusite 28
Gram, 21 grams of dark plum, 6 grams of Caulis Spatholobi, 13 grams of cortex albiziae.
The Chinese medicinal composition preparation of above-mentioned treatment bone and joint diseases is made by the following method:
Each raw material is weighed according to above-mentioned weight ratio, each raw material is cut into broken section, and then broken section of each raw material is mixed, is ground to
Powder is packed into capsule and is made as capsule, which is Oral preparation, two times a day, each taking 6 grams.
Embodiment 4
Present embodiments providing a kind of Chinese medicine composition for treating bone and joint diseases includes following components:
7 grams of Radix Angelicae Sinensis, 15 grams of Rhizoma Chuanxiong, 10 grams of safflower, 11 grams of peach kernel, 14 grams of olibanum, 5 grams of dragon's blood, 13 grams of catechu, borneol 20
Gram, 11 grams of raw madder, 8 grams of pilose antler, 5 grams of naze, 20 grams of lopseed, fragrant 0.5 gram very little, 14 grams of the rhizome of davallia, 12 grams of rhizoma atractylodis, pyrolusite
20 grams, 22 grams of dark plum, 10 grams of Caulis Spatholobi, 15 grams of cortex albiziae.
The Chinese medicinal composition preparation of above-mentioned treatment bone and joint diseases is made by the following method:
Each raw material is weighed according to above-mentioned weight ratio, cleans each raw material, removes the part of its mildew, dampness.Then, Jiang Geyuan
Material mixing, by Universalpulverizer crush be broken section, then using micronizer through broken section crush be powder to get.The powder
The preparation of last shape take after mixing it with hot water one time 6 grams, twice daily.
Embodiment 5
Present embodiments providing a kind of Chinese medicine composition for treating bone and joint diseases includes following components:
5 grams of Radix Angelicae Sinensis, 5 grams of Rhizoma Chuanxiong, 6 grams of safflower, 3 grams of peach kernel, 8 grams of olibanum, 1~8 gram of dragon's blood, 6 grams of catechu, 10 grams of borneol,
10 grams of raw madder, 4 grams of pilose antler, 2 grams of naze, 10 grams of lopseed, fragrant 0.5 gram very little, 10 grams of the rhizome of davallia, 10 grams of rhizoma atractylodis, pyrolusite 10
Gram, 9 grams of dark plum, 4 grams of Caulis Spatholobi, 10 grams of cortex albiziae, 8 grams of monkshood, 10 grams of radix aconiti agrestis, 10 grams of vomiting nut.
The Chinese medicinal composition preparation of above-mentioned treatment bone and joint diseases is made by the following method:
Firstly, raw material is divided into two equal portions according to weight according to each raw material of above-mentioned weight weighing.
Secondly, each raw material in a copy of it is mixed, it is ground to powder, powder is made.Wherein another it will use decocting
It boils 20 minutes, filter and remove residue obtains filtrate.Again, filtrate is mixed with powder, is boiled 2 hours at 80 DEG C, then at 45 DEG C
It is lower tanning 10 hours, until reach the state of dropping into a bead to get.
The Chinese medicine composition is external drug, and affected part is cleaned up, is wiped, the above-mentioned ointment being fabricated to is pasted on
Affected part.Every 8 grams of patch, replacement in 48 hours are primary.
Embodiment 6
Present embodiments providing a kind of Chinese medicine composition for treating bone and joint diseases includes following components:
20 grams of Radix Angelicae Sinensis, 20 grams of Rhizoma Chuanxiong, 18 grams of safflower, 12 grams of peach kernel, 30 grams of olibanum, 8 grams of dragon's blood, 21 grams of catechu, borneol 34
Gram, 13 grams of raw madder, 10 grams of pilose antler, 5 grams of naze, 21 grams of lopseed, fragrant 1 gram very little, 23 grams of the rhizome of davallia, 15 grams of rhizoma atractylodis, pyrolusite
30 grams, 24 grams of dark plum, 11 grams of Caulis Spatholobi, 17 grams of cortex albiziae, 14 grams of monkshood, 12 grams of radix aconiti agrestis, 23 grams of vomiting nut.
Be two parts of A, B by raw material firstly, according to each raw material of above-mentioned weight weighing, A parts with B parts of weight ratio 1:2.
Secondly, each raw material in A parts is mixed, it is ground to powder, powder is made.10 points are impregnated in 25 DEG C of water by B parts
Then clock decocts 50 minutes, filter and remove residue obtains filtrate.Again, filtrate is mixed with powder, heats and endures under the conditions of 100 DEG C
System 2 hours, then boiled 10 hours at 55 DEG C, until reach the state of dropping into a bead to get.The Chinese medicine composition be it is sticky,
There is aromatic odor.
The Chinese medicine composition is external drug, and affected part is cleaned up, is wiped, and the above-mentioned ointment being fabricated to is utilized temperature
Water heating, is then pasted on affected part.Every 8 grams of patch, replacement in 50 hours are primary.
Embodiment 7
Present embodiments providing a kind of Chinese medicine composition for treating bone and joint diseases includes following components:
10 grams of Radix Angelicae Sinensis, 10 grams of Rhizoma Chuanxiong, 10 grams of safflower, 6 grams of peach kernel, 10 grams of olibanum, 6 grams of dragon's blood, 6 grams of catechu, 10 grams of borneol,
10 grams of raw madder, 6 grams of pilose antler, 5 grams of naze, 10 grams of lopseed, fragrant 0.5 gram very little, 10 grams of the rhizome of davallia, 10 grams of rhizoma atractylodis, pyrolusite 10
Gram, 10 grams of dark plum, 10 grams of Caulis Spatholobi, 10 grams of cortex albiziae, 10 grams of monkshood, 10 grams of radix aconiti agrestis, 10 grams of vomiting nut.
Firstly, according to each raw material of above-mentioned weight weighing, raw material is divided into two parts of A, B according to weight, A parts with B parts of weight
Compare 1:3.
Secondly, each raw material in A parts is mixed, it is ground to powder, powder is made.10 points are impregnated in 26 DEG C of water by B parts
Then clock decocts 20 minutes, filter and remove residue obtains filtrate.
Again, filtrate is mixed with powder, heating tanning 2 hours, then boil under the conditions of 55 DEG C under the conditions of 90 DEG C
15 hours, until reaching the state of dropping into a bead.Finally, addition honey is reconciled, solid.
The Chinese medicine composition is external drug, and affected part is cleaned up, is wiped, the above-mentioned ointment being fabricated to is pasted on
Affected part.Every 8 grams of patch, replacement in 60 hours are primary.
Embodiment 8
Present embodiments providing a kind of Chinese medicine composition for treating bone and joint diseases includes following components:
8 grams of Radix Angelicae Sinensis, 7 grams of Rhizoma Chuanxiong, 13 grams of safflower, 6 grams of peach kernel, 25 grams of olibanum, 5 grams of dragon's blood, 20 grams of catechu, 17 grams of borneol,
10 grams of raw madder, 6 grams of pilose antler, 3 grams of naze, 16 grams of lopseed, fragrant 0.7 gram very little, 16 grams of the rhizome of davallia, 14 grams of rhizoma atractylodis, pyrolusite 13
Gram, 14 grams of dark plum, 9 grams of Caulis Spatholobi, 15 grams of cortex albiziae, 12 grams of monkshood, 10 grams of radix aconiti agrestis, 22 grams of vomiting nut.
Be two parts of A, B by raw material firstly, according to each raw material of above-mentioned weight weighing, A parts with B parts of weight ratio 2:3.
Secondly, each raw material in A parts is mixed, it is ground to powder, powder is made.B parts are decocted 20 minutes with water, filtering
It removes slag, obtains filtrate.
Again, filtrate is mixed with powder, heating tanning, until reaching the state of dropping into a bead.Finally, vaseline is added,
Carry out solid.
The Chinese medicine composition is external drug, and affected part is cleaned up, is wiped, the above-mentioned ointment being fabricated to is pasted on
Affected part.Every 8 grams of patch, replacement in 72 hours are primary.
Test example 1
Count the result of the traditional Chinese medicine composition for treating bone and joint diseases of above-described embodiment 1-8.
Evaluation standard:
Cure: symptom disappears, and can restore original work.
Effective: symptom largely disappears, and remains that slight joint part is uncomfortable or slight numbness, can restore original work.
Improve: partial symptoms disappear, and can serve as compared with light work.
Invalid: symptom does not mitigate or aggravates, and can not work.
Efficient=(healing number of cases+effective number of cases+improvement number of cases substantially)/total number of cases × 100%.
Assessment crowd:
1126 patients, male 588, female 538, the age 18-55 years old.
Treatment cycle:
It is longest March, most 2 weeks short.
Evaluating result:
698 are cured, effective and improvement 408, invalid 20, effective percentage patient medication 18 hours, can be relieved up to 98%
Clinical symptoms.
Case one
Patient: Mr. Wang, female, 44 years old.
Neck and shoulder part DOMS aggravates 2 weeks, aching of shoulder and arm on the right side of patient, food, middle finger are numb with more than numb, the unsmooth August of activity
Wood has ant row sense；When head layback or to the right flex, there is electric shock sample string picotement, is transmitted from neck root to right shoulder arm；It mentions
Shoulder, when receiving arm, bending elbow, upper limb is aching and tired with numb mitigation, before the onset without obvious trauma history.Incidence is light to the left forward to bend, cervical vertebra 6
There are tenderness and Rediating Pain in~7 right sides transverse process point front lower place；Intervertebral foramen compression test is positive, and brachial plexus distraction test is positive.X-ray film
Show: cervical vertebrae physiological lordosis radian straightens, and 6~7 uncovertebral joint of neck has spur hyperplasia, and intervertebral foramen is slightly narrow.
Diagnosis: nerve root cervical vertebra sickness.
Treatment: card belongs to decline of kidney-YANG, asthenia of essence and blood, muscles and bones dystrophy；In addition Cold-dampness, vim and vigour discord, channels and collaterals lose in logical
Freely.It after giving 1 week for the treatment of, braces up, dizziness mitigates, and all diseases alleviate；It is continuous to take a week, neck, shoulder, arm and the numbness of fingers
It is substantially reduced.Behind drug 2 weeks that the offer of the embodiment of the present invention 7 is continuously provided, start the 2nd course for the treatment of third moon, takes medicine two weeks, disease
Shape completely disappears, and cervical vertebra moving is good, and x ray photograph check shows that cervical vertebrae physiological curve restores normal.It is visited after half a year, has restored work
Make, nothing else is uncomfortable.
Case two
Patient: week certain, male, 36 years old
Aching pain in waist and back 8 years, companion's left lower extremity pain, numbness, because getting injured by a fall lumbosacral region, felt waist after exogenous disease rheumatism before 1 year, patient 8 years
The stiff pain of flesh, daytime light night weight, is gradually aggravated, the morning stiffness time 30-60 minutes.Lumbar spine activity is restricted the curved, ridge in slight left side
Column and sacral joint tenderness, pelvic compression and separation test are positive；In chemical examination hemoglobin 95g/l, erythrocyte sedimentation rate 32mm/1h, class wind
The wet factor (-).X-ray is shown: zygapophyseal joint gap is fuzzy, disappears, calcification that posterior longitudinal ligament is slight；Articular surface hardening, gap hair
Rough, the visible cystis degeneration in left side, 1/3 ligament calcification is obvious under joint.
Diagnosis: ankylosing spondylitis.
Treatment: continuously take the offer of the embodiment of the present invention 5 drug it is continuous take 3 months after, pain in waist and lower extremities is relieved；Patient
Subjective symptoms disappears, and activity is as usual, and afterwards with this drug after treatment 5 months, follow-up 2 years, curative effect was stablized.
Case three
Patient: Sun, male, 63 years old.
Knee joint swelling and pain aggravated one week with activity unsmooth more than 1 year.Sometimes pain can be in radioactivity, as hip arthralgia can
Femoribus internus is radiated to, near knee joint.Early stage visible joint is stiff, there is the symptoms such as soft knee, semi-crouch pain, stair activity pain, from
Feel activity is unfavorable, and joint flexion-extension motion range reduces and walking ability decline.Physical examination: (1) gonalgia, interior Xiyan or outer knee
Eye has tenderness；(2) kneecap cartilage friction test, semi squat test are the positive, or have that atrophy of quadriceps femoris, to stretch knee applied voltage test equal
For positive etc..(3) walking-function l grades or 0 grade；Knee bends 10 °~20 °, stretches 10 °~15 ° or so.X ray photograph is shown: kneecap edge
Visible hyperplasia sample changes, and joint space is asymmetric or narrows.
Diagnosis: knee joint retrogression pathological changes.
Treatment:, drug 1 month for continuously taking the offer of the embodiment of the present invention 3, oedema, pain symptom mitigate, patient activity
It is more light.It advises and takes a good rest, carry out joint motions exercise daily, keep good mechanics position, reduce joint stress；Control
Weight or weight-reducing；It avoids standing and walking over long distances for a long time；Arthrotrauma, infection, metabolic disorder, bone are treated in time and properly
The protopathy such as matter is loose；It replenishes the calcium.
Case four
Patient: Zhang, female, 22 years old.
Before 2 months, when patient's aggravating activities, leads to right sprain of ankle joint accidentally, lead to right ankle-joint pain and swelling, Bu Nenghang
It walks, is aggravated after activity.
Training inspection: bottom right limbs are without deformity, right ankle swelling, and local skin has no ecchymosis piece, Pi Wen is slightly without rubescent
Height, medial and lateral malleolus tenderness, ankle moving is limited, does not touch bone rubbing feeling, and peripheral blood fortune is felt good, bottom right limb adynamia, flesh
Power is normal, knee hip joint no abnormality seen, remaining limbs no abnormality seen, and physiological reflex exists, and pathologic reflex is not drawn.
Auxiliary examination: right ankle-joint positive side position x-ray shows: right each sclerotin no abnormality seen of ankle-joint, joint space are clear.
Diagnosis: right sprained ankle
Treatment: behind drug 3 days for continuously taking the offer of the embodiment of the present invention 2, pain, swelling are substantially reduced, continue to give 2
After week treatment, walking is slightly convenient.
Five patient of case: Mr. Wang, male, 46 years old.
Left forearm swelling moving obstacle.Weight injures left forearm by a crashing object, causes left forearm swelling, pain and moving obstacle.Hurt future trouble
Person is without stupor history, five Nausea and vomitings.It claps x line piece to show: " left radius lower section comminuted fracture ".Patient's mind is clear after wound, spirit
Difference does not carry out excrement and urine not into diet.
Physical examination: body temperature: 36.2 DEG C, pulse: 80 beats/min, breathing: 18 beats/min, blood pressure: 120/80mmHg.
Orthopaedics situation: backbone physiological camber is normal, and activity is freely.Pelvic compression, separation test (-), saddle area feel just
Often.Right upper extremity and double lower limb movement feel that blood fortune is normal.Left shoulder, exercising elbow joint are normal.It is left forearm lower section pain, livid purple
Swelling, the dynamic degree of local anomaly, left wrist joints moving obstacle, accessible obvious bone sassafras sense.Local skin temperature is slightly higher.Left hand tip sense
Feel, movement, blood fortune are normal.The bilateral upper arm two, three musculotendinous (++)；Bilateral knee, heel string, reflection (++)；Bilateral Hough Mans
Sign, babinski's sign are negative.
Auxiliary examination: x line piece shows: left radius lower section comminuted fracture.
Diagnosis: left radius comminuted fracture
Diagnosis and treatment process and discharge situation: the external application of Chinese medicine, the fixed braking of the offer of the embodiment of the present invention 7 are given；Take orally this hair
The medicine for oral administration that bright embodiment 2 provides, patient tell that affected limb swelling is substantially reduced.Check x line piece shows: distal end cortical bone is owed in left radius
Several linear low-density shadows are shown in finishing, and broken ends of fractured bone dislocation is unobvious, and remaining bony structures are complete, has no fracture, destroys sign, joint
Face finishing, joint space are clearly even.Continue outer fixed, the wrapping of dressing in 3-6 days, oral traditional Chinese medicine for oral administration.It is multiple after treatment in 3 months
Look into x line piece to show: distal end cortical bone is continuous in left radius, and ossis is unobstructed, and bony structures are more complete.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field
For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, made any to repair
Change, equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.
Claims (11)
1. a kind of for treating the Chinese medicine composition of bone and joint diseases, which is characterized in that including following components: by weight,
5~20 parts of Radix Angelicae Sinensis, 5~20 parts of Rhizoma Chuanxiong, 6~18 parts of safflower, 3~12 parts of peach kernel, 8~30 parts of olibanum, 1~8 part of dragon's blood, youngster
6~21 parts of tea, 10~34 parts of borneol, 10~13 parts of raw madder, 4~10 parts of pilose antler, 2~5 parts of naze, 10~21 parts of lopseed,
Very little fragrant 0.5~1 part, 10~23 parts of the rhizome of davallia, 10~15 parts of rhizoma atractylodis, 10~30 parts of pyrolusite, 9~24 parts of dark plum, Caulis Spatholobi 4~
11 parts, 10~17 parts of cortex albiziae.
2. according to claim 1 for treating the Chinese medicine composition of bone and joint diseases, which is characterized in that the treatment bone
The Chinese medicine composition of joint disease is Oral preparation.
3. according to claim 1 for treating the Chinese medicine composition of bone and joint diseases, which is characterized in that further include following
Component: by weight, 8~14 parts of monkshood, 10~12 parts of radix aconiti agrestis, 10~23 parts of vomiting nut.
4. according to claim 3 for treating the Chinese medicine composition of bone and joint diseases, which is characterized in that the treatment bone
The Chinese medicine composition of joint disease is external preparation.
5. according to claim 4 for treating the Chinese medicine composition of bone and joint diseases, which is characterized in that further include: it assigns
Shape agent.
6. according to claim 5 for treating the Chinese medicine compositions of bone and joint diseases, the excipient include honey and/
Or vaseline.
7. a kind of production method described in claim 1 for treating the Chinese medicine composition of bone and joint diseases, which is characterized in that
All raw materials are mixed, milling, Oral preparation is made.
8. a kind of production method as claimed in claim 3 for treating the Chinese medicine composition of bone and joint diseases, which is characterized in that
Include the following steps:
Step 1): raw material is weighed according to the ratio for treating the Chinese medicine composition of bone and joint diseases, raw material is divided into A, B
Two parts, described A parts with described B parts of weight ratio 1:1~1:3；
Step 2): described A parts of each medicinal material is mixed, milling, obtains powder；
Step 3): described B parts of each medicinal material is mixed, and is decocted 20~50 minutes with water, filter and remove residue obtains filtrate；
Step 4): being added the powder in Xiang Suoshu filtrate, heating tanning is to dropping into a bead shape to get external preparation.
9. the production method according to claim 8 for treating the Chinese medicine composition of bone and joint diseases, which is characterized in that
In step 3), after mixing, before decoction, further includes: impregnate 3~10 minutes in water.
10. the production method according to claim 8 for treating the Chinese medicine composition of bone and joint diseases, feature exist
In, in step 4), heating tanning specifically:
It boils at 80~100 DEG C 2 hours or more, is then boiled 10~15 hours at 45~55 DEG C.
11. the production method according to claim 8 for treating the Chinese medicine composition of bone and joint diseases, feature exist
In after step 4), further includes: pharmaceutically acceptable excipient is added, carries out solid.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101019975A (en) * | 2007-03-14 | 2007-08-22 | 吴方忠 | Fracture treating Chinese medicine composition and its prepn |
| CN104644943A (en) * | 2015-01-27 | 2015-05-27 | 王廷见 | Traditional Chinese medicine composition, medicinal moxibustion containing same and preparation method |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101019975A (en) * | 2007-03-14 | 2007-08-22 | 吴方忠 | Fracture treating Chinese medicine composition and its prepn |
| CN104644943A (en) * | 2015-01-27 | 2015-05-27 | 王廷见 | Traditional Chinese medicine composition, medicinal moxibustion containing same and preparation method |
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