CN105381137A - Traditional Chinese medicine composition for treating osteoarticular diseases and preparing method thereof - Google Patents
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- A—HUMAN NECESSITIES
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Abstract
The invention provides a traditional Chinese medicine composition for treating osteoarticular diseases and a preparing method thereof, and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from, by weight, 5-20 parts of angelica sinensis, 5-20 parts of ligusticum wallichii, 6-18 parts of safflowers, 3-12 parts of peach seeds, 8-30 parts of frankincense, 1-8 parts of dragon's blood, 6-21 parts of acacia catechu, 10-34 parts of borneol, 10-13 parts of rubia sylvatica, 4-10 parts of corn cervi pantotrichum, 2-5 parts of pangolins, 10-21 parts of garden balsam stems, 0.5-1 part of musk, 10-23 parts of rhizoma drynariae, 10-15 parts of rhizoma atractylodis, 10-30 parts of pyrolusitum, 9-24 parts of dark plum fruits, 4-11 parts of caulis spatholobi and 10-17 parts of cortex albiziae. By means of the traditional Chinese medicine composition, osteoarticular functions of human bodies can be improved, injured bones and joints, periosteum and tissue can be repaired, and the treating effect on osteoarticular diseases can be improved.
Description
Technical field
The present invention relates to Chinese medicine field of pharmaceutical technology, in particular to a kind of Chinese medicine composition being used for the treatment of joint disease and preparation method thereof.
Background technology
Osteoarthritis comprises degeneration arthritis, proliferative arthritis, senile arthritis, joint deformity etc., is a kind of chronic joint diseases, easily causes articular cartilage degenerative disease and Secondary cases hyperosteogeny.Osteoarthritis is a kind of person in middle and old age's common disease causing arthralgia and joint function disturbance, and such as, bony spur, hyperosteogeny, cervical spondylosis, chondromalacia patella, lumbar spondylosis all belong to the category of osteoarthritis.Existing Chinese traditional treatment method many employings conservative treatment, such as, the methods such as physical therapy, acupuncture, motion are aided with physiotherapy again, can relief of symptoms and delay PD.But, curative effect is slow, cure rate is low problem that it exists.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition being used for the treatment of joint disease and preparation method thereof, the advantages such as this Chinese medicine composition is cheap, easy to use, rapid-action.
The present invention is achieved in that
The invention provides a kind of Chinese medicine composition for the treatment of joint disease, comprise following component: by weight,
Radix Angelicae Sinensis 5 ~ 20 parts, Rhizoma Chuanxiong 5 ~ 20 parts, 6 ~ 18 parts, Flos Carthami, 3 ~ 12 parts, Semen Persicae, Olibanum 8 ~ 30 parts, Sanguis Draxonis 1 ~ 8 part, 6 ~ 21 parts, catechu, Borneolum Syntheticum 10 ~ 34 parts, 10 ~ 13 parts, raw Radix Rubiae, 4 ~ 10 parts, Cornu Cervi Pantotrichum, Squama Manis 2 ~ 5 parts, Herba speranskiae tuberculatae 10 ~ 21 parts, Moschus 0.5 ~ 1 part, Rhizoma Drynariae 10 ~ 23 parts, Rhizoma Atractylodis 10 ~ 15 parts, pyrolusitum 10 ~ 30 parts, Fructus Mume 9 ~ 24 parts, Caulis Spatholobi 4 ~ 11 parts, Cortex Albiziae 10 ~ 17 parts.
When being classified as the dry root of umbelliferae angelica, can enrich blood, can invigorate blood circulation again, can stimulate the menstrual flow, again can be active.
Rhizoma Chuanxiong is irregular nodular pattern fist shape agglomerate, surperficial yellowish-brown, coarse shrinkage, and have the wheel of most parallel ridges to save, there is the similar round stem trace of depression on top, and downside and wheel joint have most little warty root trace.Matter is solid, not frangibility, section yellow-white or lark, and the loose grease chamber having yellowish-brown, cambium layer is wavy ring grain.Gas giving off a strong fragrance, bitter in the mouth, pungent.
Flos Carthami is called: red indigo plant flower, thorn Flos Carthami, belong to Compositae, Flos Carthami platymiscium, dry tubular flower, orange red, floral tube is carefully narrow, and sliver is narrow linear, and flower pesticide is yellow, and be unified into pipe, exceed outside sliver, its central authorities have stigma to expose.The special fragrance of tool, mildly bitter flavor.
Semen Persicae is the dry mature seed of rosaceous plant Fructus Persicae.Gather after fruit maturation, removing sarcocarp and nucleocapsid, take out seed, dry.There is blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, effect of relieving cough and asthma.For amenorrhea dysmenorrhea, abdominal mass abdominal mass mass in the abdomen, lung abscess acute appendicitis, injury from falling down, dryness of the intestine constipation, cough and asthma.
Olibanum is the resin that olive subject plant Boswellia carterii bark oozes out.Surface yellow-white, translucent, there is yellow-white powder, then color burn stored for a long time.Matter is crisp, and heat is softened.The plane of disruption has hyaloid or wax sample gloss.The special fragrance of tool, mildly bitter flavor.
Sanguis Draxonis is that the resin that oozes out of babassu Sanguis Draxonis fruit is through being processed into.There is analgesic therapy of invigorating blood circulation, removing stasis to stop bleeding, effect of promoting tissue regeneration and ulcer healing.For traumatic injury, trusted subordinate's stasis of blood pain, traumatic hemorrhage, skin infection is not held back.
Catechu is the peeling branch of leguminous plant catechu, dry dry soft extracts.Gather winter branch, dry, removing crust, is chopped to bulk, decocts with water, concentrated, dry.There is promoting blood circulation and stopping pain, hemostasia and promoting granulation, removing dampness sore, effect of removing heat from the lung and dissipating phlegm.Flutter the pain of injury for falling, traumatic hemorrhage, hematemesis and epistaxis, skin infection is not held back, eczema, eczema, cough due to lung-heat.
Borneolum Syntheticum is through steam distillation and recrystallization and obtaining by Compositae Herba Blumeae Balsamiferae stem and leaf or canella Borneolum Syntheticum Camphor tree branch and leaf.It can be used for excess syndrome of stroke coma, for conjunctival congestion and swelling pain, sore throat aphtha, to swell and ache for skin infection, does not hold back after bursting.
Raw Radix Rubiae, for being Rubia plants, is applicable to the order internal hemorrhage, haematemesis, hemoptysis etc. caused by bleeding due to blood-heat, and this product has the merit of hemostasis blood stasis dispelling, therefore stops blooding and do not stay the stasis of blood.
Cornu Cervi Pantotrichum is the unossified young horn with fine hair of deer.Containing compositions such as phospholipid, glycolipid, glue fat, hormone, fatty acid, aminoacid, protein and calcium, phosphorus, magnesium, sodium in Cornu Cervi Pantotrichum, as tonic invigorator, effective in cure to weakness, neurasthenia etc.
Squama Manis be by Squama Manis scute concoct form, its salty in the mouth, have detumescence suppuration, scattered silt dredging collateral, stimulate the menstrual flow, stimulating milk secretion, invigorating blood circulation analgesia.
Herba speranskiae tuberculatae is plant all herbal medicine, controls traumatic injury, skin ulcer, eczema, scabies.
Moschus has another name called Moschus, fragrant umbilicus, Moschus moschiferous umbilicus perfume are animal in deer family woods Moschus moschiferous, dry secretions in the male body note capsule of the maturation of horse Moschus moschiferous or former Moschus moschiferous, has promoting blood circulation to restore menstrual flow, effect of reducing swelling and alleviating pain.
Rhizoma Drynariae Epiphyte, root stock is used as medicine, and can continue and hinder pain relieving, treats to fall to wink and frustrates, injured bone.
Rhizoma Atractylodis root stock is used as medicine, and has dampness, changes effect that is turbid, pain relieving.
Pyrolusitum is oxide-based mineral rutile race pyrolusite stone, main containing manganese dioxide, and after excavating, removing silt and impurity, dry.It has stasis-dispelling and pain-killing, detumescence and promoting granulation, for traumatic injury, and incised wound carbuncle.
Fructus Mume is the dry almost ripe fruit of rose department plant plum, and summer gathers when fruit is closely ripe, and vexed black to complexion changed after oven drying at low temperature, it can be used for deficiency-heat and quenches one's thirst.
Caulis Spatholobi is the dry rattan of leguminous plant spatholobus suberectus.Autumn, season in winter two gather, and removing branch and leaf, section, dries.There is effect of blood circulation promoting and enriching, can rheumatic arthralgia be treated, paralysis and numbness, blood deficiency and yellow complexion.
The dry bark of Cortex Albiziae leguminous plant Herba Albiziae.Summer, Qiu Erji strip, and dry, and reason has promoting blood circulation and detumescence, the effect for the treatment of traumatic pain.
Cornu Cervi Pantotrichum, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Flos Carthami, Semen Persicae, raw Radix Rubiae, Sanguis Draxonis can nourish blood and enrich blood; the bone and muscle strengthening of spermatogenesis marrow, promotes the generation of skeleton growth and synovia, can repair impaired cartilage, periosteum; prevent osteoarthrosis from continuing to be worn; in addition, also there is blood circulation promoting and blood stasis dispelling, the blood vessel of dredging pent-up; promote the supply of nutrition; be beneficial to granulation promoting to put on flesh, protect joint, institute thinks monarch drug.Caulis Spatholobi, Olibanum, Cortex Albiziae, Rhizoma Drynariae are invigorated blood circulation, subside a swelling, pain relieving, and play mitigation to the clinical symptoms of osteoarthritis, reduce the misery of patient, improve the quality of living, institute thinks ministerial drug.Fructus Mume, catechu, pyrolusitum, Rhizoma Atractylodis treatment of arthritis and promoting collateral and channels, Borneolum Syntheticum removing dampness to relieve itching, can prevent extraneous hygrothermal environment to osteoarticular stimulation, and sharp joint is recovered, growth, and institute thinks adjuvant drug.Herba speranskiae tuberculatae, Moschus, Squama Manis pass through twelve channels and collaterals, promote vim and vigour circulation, the meridians that dredging is blocked, give full play to the effect of medicine, and institute thinks makes medicine.In a word, above-mentioned all the components interacts, and as an organic whole generation cooperative effect, integrates the curative effect playing treatment joint disease.
Preferably, the Chinese medicine composition of described treatment joint disease is Oral preparation.
A manufacture method for the Chinese medicine composition of above-mentioned treatment joint disease, comprises the following steps: by all raw material mixing, pulverizing, to obtain final product.
Preferably, also comprise following component: by weight, Radix Aconiti 8 ~ 14 parts, Radix Aconiti Kusnezoffii 10 ~ 12 parts, Semen Strychni 10 ~ 23 parts.
Radix Aconiti has another name called for Aconitum carmichjaelii Debx. perennial herb, its feeble QI, acrid in the mouth, numb tongue, for expelling wind and removing dampness, and antalgic.
Radix Aconiti Kusnezoffii is the dried root of ranunculaceae plant Aconitum kusnezoffii Reichb, excavates when autumn, stem and leaf was withered, removing fibrous root and silt, dry.Can be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain and narcotic analgesic.
Semen Strychni Loganiaceae, Logania arbor.Be used as medicine after seed is brewed, cold in nature, bitter in the mouth, has activating collaterals and eliminating stagnation, the effect of reducing swelling and alleviating pain.
Cornu Cervi Pantotrichum, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Flos Carthami, Semen Persicae, raw Radix Rubiae, Sanguis Draxonis are monarch drug, repair impaired cartilage, periosteum, are beneficial to granulation promoting and put on flesh.Caulis Spatholobi, Olibanum, Cortex Albiziae, Rhizoma Drynariae are ministerial drug, invigorate blood circulation, subside a swelling, pain relieving, alleviate the clinical symptoms of joint disease.Fructus Mume, catechu, pyrolusitum, Rhizoma Atractylodis, Borneolum Syntheticum, Radix Aconiti, Radix Aconiti Kusnezoffii, Semen Strychni are adjuvant drug, dispel the raw gas of bone joint pent-up, strengthen the resistivity of osteoarthrosis warm and humid environment to external world.Herba speranskiae tuberculatae, Moschus, Squama Manis pass through twelve channels and collaterals, have effect that is deep, transdermal, and the effective ingredient of medicine is gone directly focus, and give full play to the effect of medicine, institute thinks makes medicine.Above-mentioned each medical material interacts, and balances the efficacy of a drug of each medical material, integrally cooperative effect occurs, and integrates the curative effect playing treatment joint disease.
Preferably, the Chinese medicine composition of described treatment joint disease is external preparation.
Preferably, also comprise: excipient, preferably, described excipient comprises Mel, and/or vaseline.
A kind of manufacture method of Chinese medicine composition of above-mentioned treatment joint disease comprises the steps:
Step 1): according to the described ratio raw materials weighing being used for the treatment of the Chinese medicine composition of joint disease, raw material is divided into A, B two parts, the weight ratio 1:1 ~ 1:3 of described A part and described B part;
Step 2): by each medical material mixing of described A part, pulverizing, obtain powder;
Step 3): by the mixing of each medical material of described B part, with soak by water 20 ~ 50 minutes, filter and remove residue, obtained filtrate;
Step 4): in described filtrate, add described powder, heating boils to the beading that drips, and obtains external preparation.
First this manufacture method is got each medical material of a Chinese medicine composition and is mixed, and pulverizing, prepares powder, for subsequent use.Then get each medical material of a Chinese medicine composition and carry out mixing, with soak by water, make effective ingredient stripping in its medical material in water, after filter and remove residue, collect filtrate then.Using the filtrate of collecting as infusion liquid, powder is added in filtrate, then boils.Along with the volatilization gradually of moisture in filtrate, the jelly in filtrate is attached to powder gradually, and along with constantly being concentrated, viscosity increases gradually, until form the beading that drips.
Medical material directly decocts by traditional technology of boiling medicine, and then removes filtering residue, uses filtrate.In medicine, some effective ingredient are not easily endured out, and the effective ingredient in the filtrate that this method obtains is less, and the utilization rate of medical material, 40% ~ 50%, causes the waste of medical material.
In the present invention, the powder that Chinese crude drug is made, it keeps the property of medicine, the drug effect of crude drug, decocts more convenient.The particle diameter of powder Chinese crude drug is little, and during infusion, wherein effective ingredient more easily discharges, more easily decoct and stripping in decoction liquor.The powder be made up of Chinese crude drug, is finally used as medicine, and the utilization rate of medical material is improved, and in the Chinese medicine composition of obtained treatment joint disease, active constituent content is high.Powder is used directly and is used as medicine, and makes the medicinal ingredient of finally treating in the Chinese medicine composition of joint disease abundanter, reduces the disappearance causing medicinal ingredient owing to removing filtering residue.In addition, powder also plays the effect of thickening, is easy to molding, reduces the consumption of other non-medicinal ingredient.
Compared to the powder that direct soak by water is made up of medical material, decoct by medical material the filtrate obtained and be used as the liquid medium decocting powder, then be dissolved in effective ingredient in filtrate through repeatedly boiling, can interact fully between various effective ingredient, can be in harmonious proportion the property of medicine of each medical material, make the property of medicine milder of the Chinese medicine composition of the treatment joint disease of final preparation, zest is little.
Preferably, step 3) in, after mixing, before decoction, also comprise: soak 3 ~ 10 minutes in water.Medicine can being made fully to infiltrate moisture by soaking, making the cell imbibition in medical material, so that effective ingredient is dissolved in medical material tissue, and then by diffusing in water.In addition, protein condenses, the starch gelatinization avoided in medical material tissue can also be played to a certain extent, improve the stripping of effective ingredient.
Preferably, step 4) in, heating boils and is specially: at 80 ~ 100 DEG C, boil more than 2 hours, then at 45 ~ 55 DEG C, boil 10 ~ 15 hours.First high temperature boils, and medical material can be made fully to be heated, the effective ingredient in medical material, makes the effective ingredient Fast Stripping in medical material; Then low temperature boils, and avoids high temperature to decoct and causes the destroyed of effective ingredient for a long time.
Preferably, step 4) after, also comprise: add pharmaceutically acceptable excipient, carry out solid.
Beneficial effect of the present invention:
The invention provides a kind of Chinese medicine composition, preparation and preparation method thereof for the treatment of joint disease.This Chinese medicine composition, according to Chinese medical theory, carries out prescription in conjunction with osteoarthritis pathogeny, the medicine of this treatment osteoarthritis, has promoting flow of QI and blood, dispelling cold by warming the meridian, treatment of arthritis and promoting collateral and channels, stasis-dispelling and pain-killing effect.Each raw material is natural plants, and for the purpose of expelling wind and cold, spasmolytic dredging collateral, activating blood circulation to dissipate blood stasis, simultaneously also warming the kidney to activate YANG, strengthening the body resistance, reaches the effect of bone and muscle strengthening, treatment of arthritis disease.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but it will be understood to those of skill in the art that the following example only for illustration of the present invention, and should not be considered as limiting the scope of the invention.Unreceipted actual conditions person in embodiment, the condition of conveniently conditioned disjunction manufacturer suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, be and can buy by commercially available the conventional products obtained.
Embodiment 1
Present embodiments provide a kind of Chinese medicine composition for the treatment of joint disease and comprise following component:
Radix Angelicae Sinensis 5 grams, Rhizoma Chuanxiong 5 grams, 6 grams, Flos Carthami, 3 grams, Semen Persicae, Olibanum 8 grams, Sanguis Draxonis 1 ~ 8 gram, 6 grams, catechu, Borneolum Syntheticum 10 grams, 10 grams, raw Radix Rubiae, 4 grams, Cornu Cervi Pantotrichum, Squama Manis 2 grams, Herba speranskiae tuberculatae 10 grams, Moschus 0.5 gram, Rhizoma Drynariae 10 grams, Rhizoma Atractylodis 10 grams, pyrolusitum 10 grams, Fructus Mume 9 grams, Caulis Spatholobi 4 grams, Cortex Albiziae 10 grams.
The Chinese medicinal composition preparation of above-mentioned treatment joint disease is made by the following method:
Weigh each raw material according to above-mentioned weight ratio, each raw material is pulverized with Universalpulverizer respectively, is then mixed, be ground to powder, to obtain final product.
This Chinese medicine composition is endo-medicine, and above-mentioned powder can be taken after mixing it with water with yellow wine, and alcohol intolerance person can take after mixing it with hot water, every day twice, one time 6 grams.
Embodiment 2
Present embodiments provide a kind of Chinese medicine composition for the treatment of joint disease and comprise following component:
Radix Angelicae Sinensis 10 grams, Rhizoma Chuanxiong 10 grams, 10 grams, Flos Carthami, 6 grams, Semen Persicae, Olibanum 10 grams, Sanguis Draxonis 6 grams, 6 grams, catechu, Borneolum Syntheticum 10 grams, 10 grams, raw Radix Rubiae, 6 grams, Cornu Cervi Pantotrichum, Squama Manis 5 grams, Herba speranskiae tuberculatae 10 grams, Moschus 0.5 gram, Rhizoma Drynariae 10 grams, Rhizoma Atractylodis 10 grams, pyrolusitum 10 grams, Fructus Mume 10 grams, Caulis Spatholobi 10 grams, Cortex Albiziae 10 grams.
The Chinese medicinal composition preparation of above-mentioned treatment joint disease is made by the following method:
Weigh each raw material according to above-mentioned weight ratio, each raw material is cut into broken section, then by broken for each raw material section of mixing, be ground to powder, obtain final product.This Chinese medicine composition is endo-medicine, and boiled water is taken after mixing it with water, every day twice, one time 6 grams.
Embodiment 3
Present embodiments provide a kind of Chinese medicine composition for the treatment of joint disease and comprise following component:
Radix Angelicae Sinensis 20 grams, Rhizoma Chuanxiong 10 grams, 13 grams, Flos Carthami, 5 grams, Semen Persicae, Olibanum 8 grams, Sanguis Draxonis 8 grams, 7 grams, catechu, Borneolum Syntheticum 14 grams, 10 grams, raw Radix Rubiae, 6 grams, Cornu Cervi Pantotrichum, Squama Manis 3 grams, Herba speranskiae tuberculatae 11 grams, Moschus 0.6 gram, Rhizoma Drynariae 12 grams, Rhizoma Atractylodis 14 grams, pyrolusitum 28 grams, Fructus Mume 21 grams, Caulis Spatholobi 6 grams, Cortex Albiziae 13 grams.
The Chinese medicinal composition preparation of above-mentioned treatment joint disease is made by the following method:
Weigh each raw material according to above-mentioned weight ratio, each raw material is cut into broken section, then by broken for each raw material section of mixing, be ground to powder, incapsulate and be made as capsule, this capsule is Oral preparation, a twice-daily, each serving with 6 grams.
Embodiment 4
Present embodiments provide a kind of Chinese medicine composition for the treatment of joint disease and comprise following component:
Radix Angelicae Sinensis 7 grams, Rhizoma Chuanxiong 15 grams, 10 grams, Flos Carthami, 11 grams, Semen Persicae, Olibanum 14 grams, Sanguis Draxonis 5 grams, 13 grams, catechu, Borneolum Syntheticum 20 grams, 11 grams, raw Radix Rubiae, 8 grams, Cornu Cervi Pantotrichum, Squama Manis 5 grams, Herba speranskiae tuberculatae 20 grams, Moschus 0.5 gram, Rhizoma Drynariae 14 grams, Rhizoma Atractylodis 12 grams, pyrolusitum 20 grams, Fructus Mume 22 grams, Caulis Spatholobi 10 grams, Cortex Albiziae 15 grams.
The Chinese medicinal composition preparation of above-mentioned treatment joint disease is made by the following method:
Weigh each raw material according to above-mentioned weight ratio, clean each raw material, remove the part that it goes mouldy, makes moist.Then, each raw material is mixed, pulverized as broken section by Universalpulverizer, then utilize super micron mill to be powder through broken section of pulverizing, to obtain final product.This pulverous preparation take after mixing it with hot water one time 6 grams, every day twice.
Embodiment 5
Present embodiments provide a kind of Chinese medicine composition for the treatment of joint disease and comprise following component:
Radix Angelicae Sinensis 5 grams, Rhizoma Chuanxiong 5 grams, 6 grams, Flos Carthami, 3 grams, Semen Persicae, Olibanum 8 grams, Sanguis Draxonis 1 ~ 8 gram, 6 grams, catechu, Borneolum Syntheticum 10 grams, 10 grams, raw Radix Rubiae, 4 grams, Cornu Cervi Pantotrichum, Squama Manis 2 grams, Herba speranskiae tuberculatae 10 grams, Moschus 0.5 gram, Rhizoma Drynariae 10 grams, Rhizoma Atractylodis 10 grams, pyrolusitum 10 grams, Fructus Mume 9 grams, Caulis Spatholobi 4 grams, Cortex Albiziae 10 grams, Radix Aconiti 8 grams, Radix Aconiti Kusnezoffii 10 grams, Semen Strychni 10 grams.
The Chinese medicinal composition preparation of above-mentioned treatment joint disease is made by the following method:
First, according to each raw material of above-mentioned weight weighing, raw material is divided into two equal portions according to weight.
Secondly, by each raw material mixing in a copy of it, powder is ground to, obtained powder.Will wherein another part to be with soak by water 20 minutes, filter and remove residue, obtains filtrate.Again, filtrate is mixed with powder, at 80 DEG C, boil 2 hours, then at 45 DEG C, boil 10 hours, until reach beading state of dripping, to obtain final product.
This Chinese medicine composition is external used medicine, is cleaned up in affected part, wipes, and the above-mentioned medical ointment plaster be made into is spread on affected part.Often paste 8 grams, within 48 hours, change once.
Embodiment 6
Present embodiments provide a kind of Chinese medicine composition for the treatment of joint disease and comprise following component:
Radix Angelicae Sinensis 20 grams, Rhizoma Chuanxiong 20 grams, 18 grams, Flos Carthami, 12 grams, Semen Persicae, Olibanum 30 grams, Sanguis Draxonis 8 grams, 21 grams, catechu, Borneolum Syntheticum 34 grams, 13 grams, raw Radix Rubiae, 10 grams, Cornu Cervi Pantotrichum, Squama Manis 5 grams, Herba speranskiae tuberculatae 21 grams, Moschus 1 gram, Rhizoma Drynariae 23 grams, Rhizoma Atractylodis 15 grams, pyrolusitum 30 grams, Fructus Mume 24 grams, Caulis Spatholobi 11 grams, Cortex Albiziae 17 grams, Radix Aconiti 14 grams, Radix Aconiti Kusnezoffii 12 grams, Semen Strychni 23 grams.
First, according to each raw material of above-mentioned weight weighing, be A, B two parts, the weight ratio 1:2 of A part and B part by raw material.
Secondly, by each raw material mixing in A part, powder is ground to, obtained powder.B part soaked 10 minutes in 25 DEG C of water, then decoct 50 minutes, filter and remove residue, obtains filtrate.Again, filtrate mixed with powder, under 100 DEG C of conditions, heating boils 2 hours, then at 55 DEG C, boils 10 hours, until reach beading state of dripping, to obtain final product.This Chinese medicine composition is thickness, has aromatic odor.
This Chinese medicine composition is external used medicine, is cleaned up in affected part, wipes, and utilizes warm water to heat on the above-mentioned ointment be made into, then sticks in affected part.Often paste 8 grams, within 50 hours, change once.
Embodiment 7
Present embodiments provide a kind of Chinese medicine composition for the treatment of joint disease and comprise following component:
Radix Angelicae Sinensis 10 grams, Rhizoma Chuanxiong 10 grams, 10 grams, Flos Carthami, 6 grams, Semen Persicae, Olibanum 10 grams, Sanguis Draxonis 6 grams, 6 grams, catechu, Borneolum Syntheticum 10 grams, 10 grams, raw Radix Rubiae, 6 grams, Cornu Cervi Pantotrichum, Squama Manis 5 grams, Herba speranskiae tuberculatae 10 grams, Moschus 0.5 gram, Rhizoma Drynariae 10 grams, Rhizoma Atractylodis 10 grams, pyrolusitum 10 grams, Fructus Mume 10 grams, Caulis Spatholobi 10 grams, Cortex Albiziae 10 grams, Radix Aconiti 10 grams, Radix Aconiti Kusnezoffii 10 grams, Semen Strychni 10 grams.
First, according to each raw material of above-mentioned weight weighing, raw material is divided into A, B two parts according to weight, the weight ratio 1:3 of A part and B part.
Secondly, by each raw material mixing in A part, powder is ground to, obtained powder.B part soaked 10 minutes in 26 DEG C of water, then decoct 20 minutes, filter and remove residue, obtains filtrate.
Again, filtrate mixed with powder, under 90 DEG C of conditions, heating boils 2 hours, then under 55 DEG C of conditions, boils 15 hours, until reach beading state of dripping.Finally, add that Mel carries out being in harmonious proportion, solid.
This Chinese medicine composition is external used medicine, is cleaned up in affected part, wipes, and the above-mentioned medical ointment plaster be made into is spread on affected part.Often paste 8 grams, within 60 hours, change once.
Embodiment 8
Present embodiments provide a kind of Chinese medicine composition for the treatment of joint disease and comprise following component:
Radix Angelicae Sinensis 8 grams, Rhizoma Chuanxiong 7 grams, 13 grams, Flos Carthami, 6 grams, Semen Persicae, Olibanum 25 grams, Sanguis Draxonis 5 grams, 20 grams, catechu, Borneolum Syntheticum 17 grams, 10 grams, raw Radix Rubiae, 6 grams, Cornu Cervi Pantotrichum, Squama Manis 3 grams, Herba speranskiae tuberculatae 16 grams, Moschus 0.7 gram, Rhizoma Drynariae 16 grams, Rhizoma Atractylodis 14 grams, pyrolusitum 13 grams, Fructus Mume 14 grams, Caulis Spatholobi 9 grams, Cortex Albiziae 15 grams, Radix Aconiti 12 grams, Radix Aconiti Kusnezoffii 10 grams, Semen Strychni 22 grams.
First, according to each raw material of above-mentioned weight weighing, be A, B two parts, the weight ratio 2:3 of A part and B part by raw material.
Secondly, by each raw material mixing in A part, powder is ground to, obtained powder.By B part with soak by water 20 minutes, filter and remove residue, obtains filtrate.
Again, filtrate mixed with powder, heating boils, until reach beading state of dripping.Finally, add vaseline, carry out solid.
This Chinese medicine composition is external used medicine, is cleaned up in affected part, wipes, and the above-mentioned medical ointment plaster be made into is spread on affected part.Often paste 8 grams, within 72 hours, change once.
Test example 1
The result of the traditional Chinese medicine composition for treating joint disease of statistics above-described embodiment 1-8.
Evaluation standard:
Cure: transference cure, can original work be recovered.
Effective: symptom major part disappears, residual slight joint part is uncomfortable or slightly numb, can recover original work.
Take a turn for the better: partial symptoms disappears, and can serve as comparatively light work.
Invalid: symptom does not alleviate or increases the weight of, cannot work.
Effective percentage=(substantially curing number of cases+effective number of cases+improvement number of cases)/total number of cases × 100%.
Test and appraisal crowd:
1126 routine patients, man 588 example, female 538 example, age 18-55 year.
Treatment cycle:
The longest March, the shortest 2 weeks.
Evaluating result:
Cure 698 examples, effective and 408 examples that take a turn for the better, invalid 20 examples, effective percentage reaches 98%, and patient medication 18 hours, can alleviate clinical symptoms.
Case one
Patient: Wang, female, 44 years old.
Neck and shoulder part muscular soreness companion is numb, more than activity smooth August, increase the weight of 2 weeks, aching of the shoulder and arm on the right side of patient, food, middle finger numbness, has the sense of ant row; When head layback or to the right flex, there is electric shock sample string picotement, from neck root to right shoulder arm transmission; When carrying shoulder, receipts arm, elbow in the wrong, upper limb is aching and tired to be alleviated with numbness, and premorbid is without obvious trauma history.Incidence is gently bent left forward, and on the right side of cervical vertebra 6 ~ 7, there are tenderness and radiating pain in transverse process point front lower place; Intervertebral foramina compression test is positive, and brachial plexus distraction test is positive.X-ray film shows: cervical vertebrae physiological lordosis radian straightens, and neck 6 ~ 7 uncovertebral joint has bony spur hypertrophy, and intervertebral foramina is slightly narrow and small.
Diagnosis: cervical spondylotic radiculopathy.
Treatment: card belongs to kidney yang deficiency, asthenia of essence and blood, muscles and bones mistake is supported; In addition Cold-dampness, vim and vigour are got along well, and meridians lose in unobstructed.After giving treatment 1 week, brace up, dizziness alleviates, and all diseases alleviate; Continue and take a week, neck, shoulder, arm and numbness of the fingers obviously alleviate.Take medicine that the embodiment of the present invention 7 provides continuously after 2 weeks, started for the 2nd course for the treatment of March, two weeks of taking medicine, symptom disappears completely, and cervical vertebra moving is good, and x-ray is taken the photograph sheet check and shown that cervical vertebrae physiological curve recovers normal.Visit after half a year, resume work, nothing else is uncomfortable.
Case two
Patient: week certain, man, 36 years old
Aching pain in waist and back 8 years, companion's left lower extremity pain, numb 1 year, patient's 8 years causes get injured by a fall lumbosacral region, and feel the stiff pain of psoas muscle after diseases caused by exogenous pathogenic factor rheumatism, light night in daytime is heavy, increases the weight of gradually, morning stiff time 30-60 minute.Lumbar spine activity is restricted that slight left side is curved, spinal column and sacral joint tenderness, pelvic compression and the separation test positive; At blood test Lactoferrin 95g/l, erythrocyte sedimentation rate 32mm/1h, rheumatoid factor (-).X-ray shows: zygapophyseal joint gap is fuzzy, disappearance, calcification that posterior longitudinal ligament is slight; Articular surface hardens, gap is crude, the visible cystis degeneration in left side, and under joint, 1/3 ligament calcification is obvious.
Diagnosis: ankylosing spondylitis.
Treatment: after taking that medicine that the embodiment of the present invention 5 provides is continuous continuously and taking 3 months, lumbago and skelalgia is obviously alleviated; Patient's subjective symptoms disappears, movable as usual, rear with this medicine after treatment 5 months, follows up a case by regular visits to 2 years, stable curative effect.
Case three
Patient: grandson, man, 63 years old.
Knee joint companion's activity of swelling and ache increases the weight of one week in not smooth more than 1 year.Sometimes pain can be radioactivity, as the hip arthralgia can be radiated to femoribus internus, near knee joint.Early stage visible joint is stiff, and have the symptoms such as knee joint is soft, semi-crouch pain, stair activity pain, conscious activity is unfavorable, and joint flexion-extension motion scope reduces and walking ability declines.Have a medical check-up: (1) gonalgia, neix or outer Xiyan have tenderness; (2) patella cartilage friction test, semi squat test is the positive, or has atrophy of quadriceps femoris, stretches knee joint applied voltage test and be positive etc.(3) walking-function l level or 0 grade; Knee joint is bent 10 ° ~ 20 °, is stretched 10 ° ~ about 15 °.X-ray takes the photograph sheet display: patella edge visible hyperplasia sample changes, and joint space is asymmetric or narrow.
Diagnosis: knee joint degeneration.
Treatment:, take the medicine 1 month that the embodiment of the present invention 3 provides continuously, edema, pain symptom alleviate, and patient activity is comparatively light.Advise and take a good rest, every day carries out joint motions exercise, keeps good mechanics position, reduces joint stress; Control body weight or fat-reducing; Avoid standing for a long time and long distance walking; Treat the protopathy such as arthrotrauma, infection, Developmental and Metabolic Disorder, osteoporosis in time and properly; Replenish the calcium.
Case four
Patient: Zhang, female, 22 years old.
Before February, during patient's aggravating activities, accidentally cause right sprained ankle, cause right ankle joint pain and swelling, can not walk, activity postemphasis.
Training check: bottom right limbs without deformity, right ankle swelling, local skin is without rubescent, have no ecchymosis sheet, Pi Wen is slightly high, medial and lateral malleolus tenderness, ankle moving is limited, do not touch bone rubbing feeling, peripheral blood is transported, is felt good, and right lower extremity somatasthenia, muscular tension are normal, knee joint hip joint no abnormality seen, remaining limbs no abnormality seen, physiological reflex exists, and pathologic reflex is not drawn.
Auxiliary examination: position, right ankle joint positive side x-ray shows: each sclerotin no abnormality seen of right ankle joint, joint space is clear.
Diagnosis: right sprained ankle
Treatment: take medicine that the embodiment of the present invention 2 provides continuously after 3 days, pain, swelling obviously alleviate, and after continuing to give treatment in 2 weeks, walking is facility slightly.
Case five patient: Wang, man, 46 years old.
Left forearm swelling moving obstacle.Weight injures left forearm by a crashing object, causes left forearm swelling, pain moving obstacle.After wound, patient is without stupor history, five Nausea and vomiting.Clap x line sheet to show: " left radius hypomere comminuted fracture ".After wound, patient's mind is clear, and spirit is poor, does not enter diet, does not carry out excrement and urine.
Physical examination: body temperature: 36.2 DEG C, pulse: 80 beats/min, breathing: 18 beats/min, blood pressure: 120/80mmHg.
Orthopaedics situation: spinal column physiological camber is normal, and activity freely.Pelvic compression, separation test (-), saddle district sensation is normal.Right upper extremity and two lower extremity movement, sensation blood fortune are all normal.Left shoulder, exercising elbow joint are normal.Left forearm hypomere pain, livid purple swelling, the dynamic degree of local anomaly, left wrist joints moving obstacle, can touch the sense of obvious bone sassafras.Local skin temperature is slightly high.Left hand tip sensation, motion, blood are transported all normal.The bilateral upper arm two, three musculotendinous (++); Bilateral knee, heel string, reflection (++); Bilateral Hoffmann's sign, Babinski sign are negative.
Auxiliary examination: x line sheet shows: left radius hypomere comminuted fracture.
Diagnosis: left radius comminuted fracture
Diagnosis and treatment process and situation of leaving hospital: give the external application of Chinese medicine that the embodiment of the present invention 7 provides, fixing braking; The oral medicine that the oral embodiment of the present invention 2 provides, patient tells suffering limb swelling and obviously alleviates.Check x line sheet shows: in left radius, distal bone cortex owes polishing, sees several wire low-density shadow, and broken ends of fractured bone dislocation is not obvious, and remaining bony structures is complete, and have no fracture, destroy sign, articular surface polishing, joint space is clear even.Continue extenal fixation, wrapping of changing dressings 3-6 day, oral Chinese medicine for oral administration.After treatment in 3 months, check x line sheet shows: in left radius, distal bone cortex is continuous, and medullary cavity is unobstructed, and bony structures is more complete.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. be used for the treatment of a Chinese medicine composition for joint disease, it is characterized in that, comprise following component: by weight,
Radix Angelicae Sinensis 5 ~ 20 parts, Rhizoma Chuanxiong 5 ~ 20 parts, 6 ~ 18 parts, Flos Carthami, 3 ~ 12 parts, Semen Persicae, Olibanum 8 ~ 30 parts, Sanguis Draxonis 1 ~ 8 part, 6 ~ 21 parts, catechu, Borneolum Syntheticum 10 ~ 34 parts, 10 ~ 13 parts, raw Radix Rubiae, 4 ~ 10 parts, Cornu Cervi Pantotrichum, Squama Manis 2 ~ 5 parts, Herba speranskiae tuberculatae 10 ~ 21 parts, Moschus 0.5 ~ 1 part, Rhizoma Drynariae 10 ~ 23 parts, Rhizoma Atractylodis 10 ~ 15 parts, pyrolusitum 10 ~ 30 parts, Fructus Mume 9 ~ 24 parts, Caulis Spatholobi 4 ~ 11 parts, Cortex Albiziae 10 ~ 17 parts.
2. the Chinese medicine composition being used for the treatment of joint disease according to claim 1, is characterized in that, the Chinese medicine composition of described treatment joint disease is Oral preparation.
3. the Chinese medicine composition being used for the treatment of joint disease according to claim 1, is characterized in that, also comprises following component: by weight, Radix Aconiti 8 ~ 14 parts, Radix Aconiti Kusnezoffii 10 ~ 12 parts, Semen Strychni 10 ~ 23 parts.
4. the Chinese medicine composition being used for the treatment of joint disease according to claim 3, is characterized in that, the Chinese medicine composition of described treatment joint disease is external preparation.
5. the Chinese medicine composition being used for the treatment of joint disease according to claim 4, is characterized in that, also comprise: excipient, and preferably, described excipient comprises Mel, and/or vaseline.
6. the manufacture method being used for the treatment of the Chinese medicine composition of joint disease according to claim 1, is characterized in that, by all raw material mixing, pulverizing, and obtained Oral preparation.
7. the manufacture method being used for the treatment of the Chinese medicine composition of joint disease according to claim 3, is characterized in that, comprise the steps:
Step 1): according to the described ratio raw materials weighing being used for the treatment of the Chinese medicine composition of joint disease, raw material is divided into A, B two parts, the weight ratio 1:1 ~ 1:3 of described A part and described B part;
Step 2): by each medical material mixing of described A part, pulverizing, obtain powder;
Step 3): by the mixing of each medical material of described B part, with soak by water 20 ~ 50 minutes, filter and remove residue, obtained filtrate;
Step 4): in described filtrate, add described powder, heating boils to the beading that drips, and obtains external preparation.
8. the manufacture method being used for the treatment of the Chinese medicine composition of joint disease according to claim 7, is characterized in that, step 3) in, after mixing, before decoction, also comprise: soak 3 ~ 10 minutes in water.
9. the manufacture method being used for the treatment of the Chinese medicine composition of joint disease according to claim 7, is characterized in that, step 4) in, heating boils and is specially:
At 80 ~ 100 DEG C, boil more than 2 hours, then at 45 ~ 55 DEG C, boil 10 ~ 15 hours.
10. the manufacture method being used for the treatment of the Chinese medicine composition of joint disease according to claim 7, is characterized in that, step 4) after, also comprise: add pharmaceutically acceptable excipient, carry out solid.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101019975A (en) * | 2007-03-14 | 2007-08-22 | 吴方忠 | Fracture treating Chinese medicine composition and its prepn |
| CN104644943A (en) * | 2015-01-27 | 2015-05-27 | 王廷见 | Traditional Chinese medicine composition, medicinal moxibustion containing same and preparation method |
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| CN101019975A (en) * | 2007-03-14 | 2007-08-22 | 吴方忠 | Fracture treating Chinese medicine composition and its prepn |
| CN104644943A (en) * | 2015-01-27 | 2015-05-27 | 王廷见 | Traditional Chinese medicine composition, medicinal moxibustion containing same and preparation method |
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