CN102038817B - Medicinal composition for treating fracture and preparation method thereof - Google Patents

Abstract

The invention discloses a medicinal composition for treating fracture and a preparation method thereof. The medicinal composition is prepared from the following raw material medicaments in part by weight: 50 to 70 parts of Japanese milkwort herb, 50 to 70 parts of himalayan teasel root, 50 to 70 parts of fortune's drynaria rhizome, 40 to 60 parts of Chinese elder herb, 40 to 60 parts of scandent schefflera stem and leaf, 40 to 60 parts of glomeris, 20 to 40 parts of shortleaf kyllinga herb, 10 to 30 parts of mountain pepper and 9 to 20 parts of manchurian wildginger. The medicinal composition has the effects of promoting blood circulation, removing blood stasis, subdhing swelling, setting fractures and relieving pain, and has the unique curative effect on diseases such as traumatic injury, injury in sinews or bones, lumbar muscle strain, lumbar interveterbral disc protrusion and rheumatoid arthritis.

Description

Pharmaceutical composition of treatment fracture and preparation method thereof

Technical field

The present invention relates to a kind of pharmaceutical composition and preparing process thereof for the treatment of fracture, belong to technical field of Chinese medicine.

Background technology

[0002] At present, the medicine of treatment fracture is a lot of on the market, and they each have characteristics separately, but also deficiency are arranged respectively.According to the difference of everyone state of an illness, the therapeutic effect of some medicine also is not quite similar, so the medicine of the above-mentioned disease of various treatments can and be deposited on market, and is accepted by the patient.

Summary of the invention

Technical problem to be solved by this invention is to provide a kind of pharmaceutical composition for the treatment of fracture and preparation method thereof.This medicine has the effect of blood circulation promoting and blood stasis dispelling, detumescence, bone-setting pain stopping.For diseases such as traumatic injury, injured in the sinews or bones, lumbar muscle strain, prolapse of lumbar intervertebral disc, rheumatic arthritis original curative effect is arranged.

For solving the problems of the technologies described above, the present invention adopts following technical scheme: the pharmaceutical composition of treatment fracture, and this pharmaceutical composition is to be made by following raw medicaments in portion by weight; 50～70 parts of Herba Polygalae Japonicae, 50～70 parts of Radix Dipsacis, 50～70 parts of Rhizoma Drynariae, 40～60 parts of Herba Sambuci Chiensis, 40～60 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, roll 40～60 parts on mountain pearl, 20～40 parts of Herba Kyllingaes, 10～30 parts of Fructus Linderae Glaucaes, 9～20 parts of Herba Asaris.

In the pharmaceutical composition of above-mentioned treatment fracture, be to make preferably by following raw medicaments in portion by weight; 60 parts of Herba Polygalae Japonicae, 60 parts of Radix Dipsacis, 60 parts of Rhizoma Drynariae, 50 parts of Herba Sambuci Chiensis, 50 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, roll 50 parts on mountain pearl, 30 parts of Herba Kyllingaes, 20 parts of Fructus Linderae Glaucaes, 18 parts of Herba Asaris.

The preparation of drug combination method of aforesaid treatment fracture, this method is that preparation process is made clinical acceptable peroral dosage form routinely.

The preparation of drug combination method of aforesaid treatment fracture, this method is specifically, makes capsule by following preparation method:

A, weighting raw materials material Herba Polygalae Japonicae, Radix Dipsaci, Rhizoma Drynariae, Herba Sambuci Chiensis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), roll mountain pearl, Herba Kyllingae, Fructus Linderae Glaucae and Herba Asari, clean, dry;

B, with above-mentioned pulverizing medicinal materials, cross 80 mesh sieves, insert capsule then No. 0, promptly.

According to Chinese medical theory, " Herba Polygalae Japonicae " Herba Polygalae Japonica in the side, [English name] Japanese Milkwort Herb is for crossing the herb of the will plant Herba Polygalae Japonicae Polygala japonica Houtt. of section.Property is put down, acrid in the mouth, hardship.Promoting blood circulation to remove blood stasis is arranged, detoxifcation pain relieving effect." Radix Dipsaci " [English name] English name Himalayan Teasel Root, [Latin medicine name] Radix Dipsaci Asperoidis, bitter in the mouth; Hot; Slightly warm in nature.Return liver; Kidney channel.There are invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, continuous folding to hinder effect; " Rhizoma Drynariae ", [English name] RHIZOMA DRYNARIAE, hardship, temperature.Return kidney, Liver Channel.The kidney invigorating bone strengthening, the continuous pain relieving effect of hindering are arranged." Herba Sambuci Chiensis " [latin name] Herba Sambuci Chiensis sambucus javanica Reinw, warm in nature, bitter in the mouth.Promoting blood circulation to remove blood stasis, dispelling, collateral-activating effect are arranged." Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) " [Latin literary fame] Radix Schefflerae Arboricolae, Caulis et Folium Schefflerae Arboricolae, [another name] lobule Cortex schefflerae octophyllae, Radix Schefflerae Arboricolae, seven leaves are mashed, the Canis familiaris L. foot is crowed, hands tree, seven Cortex Acanthopanacis Radicis, seven leaf rattans.Acrid in the mouth; Little hardship; Warm in nature.Wind-expelling pain-stopping, promoting blood circulation and detumescence effect are arranged." roll the mountain pearl ", [another name] Prospiroboli joannsi, arhat, all for Glomeridae animal glomeris nipponica.[English name] Millepede, [Latin literary fame] Prospiroboli joannsi, acrid in the mouth; Salty; Warm in nature, return kidney channel.Dispelling wind and removing obstruction in the collateral, eliminating stasis to stop pain effect are arranged." Herba Kyllingae ", [Latin formal name used at school]: Kyllinga brevifolia Rottb is herb or the root of sedge Herba Kyllingae.Property is put down, acrid in the mouth.Dispelling wind to relieve the exterior syndrome, clearing away heat-damp and promoting diuresis, removing blood stasis to reduce swelling effect are arranged." Fructus Linderae Glaucae " [English name] Fruit of Greyblue Spicebush, [another name] Fructus Zanthoxyli Plansipini, Eumeces Chinensis is grey, Thunder God is sharp, wild pepper, Cortex Linderae Fragrantis, red, smelly Camphor tree of short, bristly hair or beard.Warm in nature, acrid in the mouth.Attach to the lung and stomach meridians.Warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain effect are arranged." Herba Asari " [Latin formal name used at school] Radix et Rhizoma Asari, warm in nature, acrid in the mouth; Return lung, kidney, heart channel.Expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention effect are arranged.All medicine 5 usefulness, the effect of playing blood circulation promoting and blood stasis dispelling, detumescence, bone-setting pain stopping altogether.The present invention can be made into peroral dosage form (as tablet, granule, capsule, soft capsule, drop pill, pill, syrup, oral liquid etc.), be used for diseases such as traumatic injury, injured in the sinews or bones, lumbar muscle strain, prolapse of lumbar intervertebral disc, rheumatic arthritis, have more satisfactory therapeutic effect.

Model case of the present invention:

1, Wang Xu, man, 8 years old, right femur strength comminuted fracture, the reduction of the fracture is fixed in advance, takes the pain relieving in 10～20 minutes of our medicine, and swelling in second day disappears, week x line perspective, see the epiphysis good apposition, callus has been grown more than 75%, and is movable down, recovery from illness in 20 days.

2, Deng Junyin, the man, 35 years old, the dried double fracture of left radius and ulna became crush type, the reduction of the fracture is fixed in advance, takes the pain relieving in 10～20 minutes of our medicine, and swelling in second day disappears, week x line perspective, see the epiphysis good apposition, callus has been grown more than 75%, comes into play recovery from illness in 20 days.

3, Wang Yuejin, the man, 51 years old, pygostyle comminuted fracture and 7 root bones fracture, the reduction of the fracture is fixed in advance, takes the pain relieving in 10～20 minutes of our medicine, and swelling in second day disappears, and a week, ground was movable down, recovery from illness in 16 days.

4, Deng Zuxing, the man 23 years old, falls from the 5th buildings and to cause lumbar vertebra the 3rd joint bursting fracture, tibiofibula is done two bone meal fragility fracture and the whole joints of calcaneus collapsed fracture, the reduction of the fracture is fixed in advance, takes the pain relieving in 20～30 minutes of this prescription, and swelling in the 3rd day disappears, fortnight x line perspective is seen the epiphysis good apposition, oneself grows callus more than 75%, and ground was movable under 20 days began, the one and a half months recovery from illness.

5, Lei Yang, the man, 22 years old, the lumbar vertebra comminuted fracture was taken the pain relieving in 10～20 minutes of our medicine, can descend ground movable on the 3rd day, can do x line fluoroscopic examination voluntarily on the 5th day, recovery from illness in 10 days.

6, Zhou Kaiyu, the woman, 55 years old, the dried double fracture of left radius and ulna became crush type, treats a wheat harvesting period in the Guizhou Province People ' s Hospital, and the disconnected part of institute has not a particle of callus formation through x line perspective, and is the same when disconnected as before.The back was with our medicine i0 days, and through X line perspective fracture good apposition, callus has been grown more than 75%, comes into play recovery from illness in 28 days.

Curative effect of the present invention: through using example surplus the various fracture 1000 of Drug therapy of the present invention, effect is remarkable.Pain relieving in 10～30 minutes after the general medication, swelling in 1～2 day disappears, and callus can be grown more than 75% in 6～9 days.Can fully recover in average about 20 days.Do not find untoward reaction.

Compared with the prior art, medicine of the present invention has the effect of blood circulation promoting and blood stasis dispelling, detumescence, bone-setting pain stopping, and diseases such as traumatic injury, injured in the sinews or bones, lumbar muscle strain, prolapse of lumbar intervertebral disc, rheumatic arthritis are had original curative effect.

The specific embodiment

Embodiment 1.Weighting raw materials material Herba Polygalae Japonicae 60g, Radix Dipsaci 60g, Rhizoma Drynariae 60g, Herba Sambuci Chiensis 50g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 50g, roll mountain pearl 50g, Herba Kyllingae 30g, Fructus Linderae Glaucae 20g, Herba Asari 18g.Clean, dry, pulverize, cross 80 mesh sieves, insert capsule then No. 0, every dress 0.5g promptly gets capsule of the present invention.Oral, be grown up each 6, the child reduces by half.Every day 4 times is with eliminating cold for resuscitation water or HUANGBAI(sic) (medicine) to be taken with wine.Also formulation method is made peroral dosage forms such as tablet, granule, soft capsule, drop pill, pill, syrup, oral liquid routinely.

Embodiment 2.Weighting raw materials material Herba Polygalae Japonicae 50g, Radix Dipsaci 50g, Rhizoma Drynariae 50g, Herba Sambuci Chiensis 40g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 40g, roll mountain pearl 40g, Herba Kyllingae 20g, Fructus Linderae Glaucae 10g, Herba Asari 9g.Clean, dry, pulverize, cross 80 mesh sieves, formulation method is made tablet routinely then.

Embodiment 3.Weighting raw materials material Herba Polygalae Japonicae 70g, Radix Dipsaci 70g, Rhizoma Drynariae 70g, Herba Sambuci Chiensis 60g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 60g, roll mountain pearl 60g, Herba Kyllingae 40g, Fructus Linderae Glaucae 30g, Herba Asari 20g.Clean, dry, pulverize, cross 80 mesh sieves, formulation method is made granule routinely then.

Claims (4)

1. pharmaceutical composition for the treatment of fracture, it is characterized in that: this pharmaceutical composition is to be made by following raw medicaments in portion by weight; 50～70 parts of Herba Polygalae Japonicae, 50～70 parts of Radix Dipsacis, 50～70 parts of Rhizoma Drynariae, 40～60 parts of Herba Sambuci Chiensis, 40～60 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, roll 40～60 parts on mountain pearl, 20～40 parts of Herba Kyllingaes, 10～30 parts of Fructus Linderae Glaucaes, 9～20 parts of Herba Asaris.

2. the pharmaceutical composition of treatment fracture according to claim 1, it is characterized in that: this pharmaceutical composition is to be made by following raw medicaments in portion by weight; 60 parts of Herba Polygalae Japonicae, 60 parts of Radix Dipsacis, 60 parts of Rhizoma Drynariae, 50 parts of Herba Sambuci Chiensis, 50 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, roll 50 parts on mountain pearl, 30 parts of Herba Kyllingaes, 20 parts of Fructus Linderae Glaucaes, 18 parts of Herba Asaris.

3. the preparation of drug combination method of a treatment as claimed in claim 1 or 2 fracture, it is characterized in that: this method is that preparation process is made clinical acceptable peroral dosage form routinely.

4. the preparation of drug combination method of treatment fracture according to claim 3, it is characterized in that: this method is to make capsule by following preparation method;

A, weighting raw materials material Herba Polygalae Japonicae, Radix Dipsaci, Rhizoma Drynariae, Herba Sambuci Chiensis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), roll mountain pearl, Herba Kyllingae, Fructus Linderae Glaucae and Herba Asari, clean, dry;

B, with above-mentioned pulverizing medicinal materials, cross 80 mesh sieves, insert capsule then No. 0, promptly.