CN104107266A - Bone-strengthening tablet - Google Patents
Bone-strengthening tablet Download PDFInfo
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- CN104107266A CN104107266A CN201310137738.8A CN201310137738A CN104107266A CN 104107266 A CN104107266 A CN 104107266A CN 201310137738 A CN201310137738 A CN 201310137738A CN 104107266 A CN104107266 A CN 104107266A
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- 238000005728 strengthening Methods 0.000 title abstract description 32
- 239000003814 drug Substances 0.000 claims abstract description 31
- 208000001132 Osteoporosis Diseases 0.000 claims abstract description 29
- 210000003734 kidney Anatomy 0.000 claims abstract description 16
- 241000237636 Pheretima Species 0.000 claims abstract description 10
- 241000208340 Araliaceae Species 0.000 claims abstract description 9
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 9
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 9
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 9
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 9
- 235000008434 ginseng Nutrition 0.000 claims abstract description 9
- 210000004185 liver Anatomy 0.000 claims abstract description 9
- 229940079593 drug Drugs 0.000 claims abstract description 8
- 238000002360 preparation method Methods 0.000 claims abstract description 8
- 238000000034 method Methods 0.000 claims abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 claims description 12
- 239000000843 powder Substances 0.000 claims description 9
- 230000002950 deficient Effects 0.000 claims description 8
- 238000005242 forging Methods 0.000 claims description 8
- 210000000629 knee joint Anatomy 0.000 claims description 8
- 239000008187 granular material Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 239000006187 pill Substances 0.000 claims description 4
- 241001446509 Psoralea Species 0.000 claims 3
- 241001523579 Ostrea Species 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 230000007812 deficiency Effects 0.000 abstract description 7
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- 238000001035 drying Methods 0.000 abstract 1
- 210000003127 knee Anatomy 0.000 abstract 1
- 238000011031 large-scale manufacturing process Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 description 31
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- 230000035876 healing Effects 0.000 description 10
- 238000010438 heat treatment Methods 0.000 description 10
- 238000000554 physical therapy Methods 0.000 description 10
- 208000024891 symptom Diseases 0.000 description 10
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
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- 230000008506 pathogenesis Effects 0.000 description 2
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- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 206010006956 Calcium deficiency Diseases 0.000 description 1
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- 210000003189 scaphoid bone Anatomy 0.000 description 1
- 108010048734 sclerotin Proteins 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a bone-strengthening tablet. The bone-strengthening tablet is a medicine for treating liver and kidney deficiency and discomfort in waist and knees, concretely is a Chinese patent medicine prepared by taking Chinese herbal medicines as raw materials, and is capable of treating osteoporosis. The invention also relates to a preparation method of the medicine. The bone-strengthening tablet is an oral table prepared by taking cornu cervi pantotrichum (removing hair), fructus psoraleae, cornu cervi degelatinatum, radix rehmanniae preparata, concha ostreae (calcined), radix dipsaci, radix ginseng rubra , radix angelicae sinensis, panax notoginseng, rhizoma atractylodis macrocephalae (fried), radix polygoni multiflori (processed), fructus corni, fructus lycii and pheretima as bulk drugs, and performing screening, drying and crushing on the raw materials through a provided tablet preparation technology. The provided formula is definite in therapeutic effect, and the tablet is an ideal medicine capable of rapidly treating osteoporosis. The tablet is simple in preparation method, easy to process and easy for large-scale production.
Description
Technical field
The present invention relates to one, to treat Liver and kidney deficient, and the pharmaceutical composition of waist knee joint unfavorable (osteoporosis), relates in particular to a kind for the treatment of Liver and kidney taking Chinese herbal medicine as crude drug deficient, Chinese medicine composition of waist knee joint unfavorable (osteoporosis) and preparation method thereof.
Background technology
Osteoporosis without this name of disease, according to its etiology and pathogenesis and clinical manifestation, surely belongs to the scope of " atrophic debility of bones " in Chinese medicine, kidney governing bones, store essential substances and raw marrow, suffering from a deficiency of the kidney is the major reason that osteoporosis occurs, the kidney essense abundance biochemistry of bone marrow is active, skeleton just can obtain the abundant nourishing of bone marrow and firm strong, if kidney-jing deficiency is few, the change source deficiency of bone marrow, can not moisten nourishing bone bone, occur that sclerotin fragility is unable, cause osteoporosis.Spleen governing limbs is the foundation of acquired constitution, source of generating QI and blood, and the main bones of the body, are the pivot of QI and blood lifting, change angry hemospermia pool with the congenital essence of supplementing nutrition, if insufficiency of the spleen, disturbance in functioning of QI, the deficiency of vital energy can not be filled and be reached, and blood deficiency can not be moistened and be supported and the osteoporosis that arrives.Therefore, insufficiency of the spleen is another key factor that osteoporosis occurs, " be association of activity and inertia " with Chinese medicine " internal organs are relevant " and the theory of " treatment must aim at the pathogenesis of disease " and " preventing diseases instead for the treatment of diseases " in conjunction with the clinical experimental study of modern medicine, the main minister side of bone strengthening sheet is kidney and spleen invigorating, benefiting QI and nourishing blood, side's effect that bone strengthening promotes the production of body fluid.In we taking Cornu Cervi Pantotrichum as monarch drug, kidney-replenishing, benefiting essence-blood, bone and muscle strengthening, main lumbago and backache; Radix Ginseng Rubra, Radix Angelicae Sinensis benefiting qi and nourishing blood, Radix Rehmanniae Preparata, Fructus Corni, Fructus Lycii, the kidney invigorating and essence nourishing, Radix Dipsaci, the Cortex Eucommiae, Cornu Cervi Degelatinatum helps Cornu Cervi Pantotrichum tonification kidney yang, and Radix Polygoni Multiflori nourishes blood, and benefit essence, adds marrow, all medicines can make YANG promoting growth while YIN promoting generation above, and sun is long cloudy raw, and help the biochemistry of QI and blood marrow, and reach effect of bone and muscle strengthening, be ministerial drug altogether.Radix Notoginseng, Pheretima, and blood stimulates the menstrual flow, blood stasis dispelling blood and tissue regeneration promoting blood, invigorating middle warmer has and disappears again, makes all building up one's health by taking tonic and oiliness, the most calcium deficiency of sufferers of osteoporosis face, Concha Ostreae calcium content is high, can reach the object of calcium-tonifying bone-strengthening.Total full side, collection reinforcing the kidney to strengthen the bone, vigorate qi and replenish the blood, warming YANG to expel cold seen, relaxing muscles and tendons to promote blood circulation, the effect of removing obstruction in the collateral to relieve pain and strengthening vital QI to eliminate pathogenic factors, the merit for the treatment of both the principal and secondary aspects of a disease is integrated, for constitutional and secondary osteoporosis, in conjunction with the clinical practice application of nearly 3 years, obtain satisfied curative effect.
Summary of the invention
It is deficient at treatment Liver and kidney that the present invention brings into play Chinese medicine, and the advantage of waist knee joint unfavorable (osteoporosis), provides a kind for the treatment of Liver and kidney evident in efficacy, with low cost, that toxic and side effects is little deficient, the pharmaceutical composition of waist knee joint unfavorable (osteoporosis).
technology realizes approach
It is deficient that the present invention is that one is treated Liver and kidney, and the pharmaceutical composition of waist knee joint unfavorable (osteoporosis), is mainly made up of the component of following weight portion:
Cornu Cervi Pantotrichum (unhairing) 7.9g Fructus Psoraleae 15.8g Cornu Cervi Degelatinatum 47.3g Radix Rehmanniae Preparata 23.7 g
Concha Ostreae (forging) 23.7 g Radix Dipsaci 7.9 g Radix Ginseng Rubra 7.9 g Radix Angelicae Sinensis 23.7 g
The Radix Notoginseng 15.8 g Rhizoma Atractylodis Macrocephalae (stir-fry) 23.7 g Radix Polygoni Multiflori (system) 23.7 g Fructus Corni 23.7 g
Fructus Lycii 23.7 g Pheretima 15.8 g
Pharmaceutical composition of the present invention is deficient based on Chinese medicine Liver and kidney, the differential diagnosis of diseases of waist knee joint unfavorable (osteoporosis) and the dialectical principle that combines, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, reinforce insufficiency and reduce excessiveness, filter out the natural plant of YANG invigorating bone strengthening, QI invigorating YANG invigorating, promoting blood circulation and hemostasis, spleen invigorating dredging collateral, according to theory of Chinese medical science prescription, be prepared from according to certain weight proportion.
Pharmaceutical composition of the present invention is through super-dry, pulverizing, and fine powder is crossed 100 mesh sieves, obtains medicated powder, put into medicated powder with 50% ethanol, stir, cross 14 mesh sieve granulations, dry by 50～60 DEG C, add 1% magnesium stearate, by 12 mesh sieves, granulate, uses tablet machine tabletting, coating, press mold, subpackage are made tablet.
The present invention's herbal raw material used all can be buied from pharmaceuticals, and it meets national medical standard.
usage and consumption:
Oral, 2～3 of preventive doses one time, 2 times on the one; 4 of therapeutic doses one time, 2 times on the one; Child is cut down according to the circumstance or is followed the doctor's advice
Detailed description of the invention
Further describe by the following examples the present invention, should be noted that these embodiment, only for the object of illustration, never limit the scope of the invention.
The preparation of [embodiment 1] tablet, takes each raw material by following weight:
Cornu Cervi Pantotrichum (unhairing) 7.9g Fructus Psoraleae 15.8g Cornu Cervi Degelatinatum 47.3g Radix Rehmanniae Preparata 23.7 g
Concha Ostreae (forging) 23.7 g Radix Dipsaci 7.9 g Radix Ginseng Rubra 7.9 g Radix Angelicae Sinensis 23.7 g
The Radix Notoginseng 15.8 g Rhizoma Atractylodis Macrocephalae (stir-fry) 23.7 g Radix Polygoni Multiflori (system) 23.7 g Fructus Corni 23.7 g
Fructus Lycii 23.7 g Pheretima 15.8 g
By the pharmaceutical composition of above-mentioned weight, through super-dry, pulverizing, fine powder is crossed 100 mesh sieves, obtains medicated powder, put into medicated powder with 50% ethanol, stir, cross 14 mesh sieve granulations, dry by 50～60 DEG C, add 1% magnesium stearate, by 12 mesh sieves, granulate, uses tablet machine tabletting, coating, press mold, subpackage are made tablet.
The preparation of [embodiment 2] powder takes each raw material by following weight:
Cornu Cervi Pantotrichum (unhairing) 7.9g Fructus Psoraleae 15.8g Cornu Cervi Degelatinatum 47.3g Radix Rehmanniae Preparata 23.7 g
Concha Ostreae (forging) 23.7 g Radix Dipsaci 7.9 g Radix Ginseng Rubra 7.9 g Radix Angelicae Sinensis 23.7 g
The Radix Notoginseng 15.8 g Rhizoma Atractylodis Macrocephalae (stir-fry) 23.7 g Radix Polygoni Multiflori (system) 23.7 g Fructus Corni 23.7 g
Fructus Lycii 23.7 g Pheretima 15.8 g
Each above-mentioned weight raw material is mixed, pulverize by after 200 mesh sieves, sieve, mix, play granule, granulate, subpackage, make powder
The preparation of [embodiment 3] small honey pill, takes each raw material by following weight:
Cornu Cervi Pantotrichum (unhairing) 7.9g Fructus Psoraleae 15.8g Cornu Cervi Degelatinatum 47.3g Radix Rehmanniae Preparata 23.7 g
Concha Ostreae (forging) 23.7 g Radix Dipsaci 7.9 g Radix Ginseng Rubra 7.9 g Radix Angelicae Sinensis 23.7 g
The Radix Notoginseng 15.8 g Rhizoma Atractylodis Macrocephalae (stir-fry) 23.7 g Radix Polygoni Multiflori (system) 23.7 g Fructus Corni 23.7 g
Fructus Lycii 23.7 g Pheretima 15.8 g
Each above-mentioned weight raw material is mixed, pulverized after 120 mesh sieves, add the Mel of having refined by 1:0.8, close and stick together, pill, selects ball, and subpackage is made small honey pill.
[test example]
The clinical observation on the therapeutic effect test of medicine composite for curing osteoporosis of the present invention.
One, the physical data of subjects: be out-patient, 400 routine patients with osteoporosis are divided into treatment group and matched group at random, patient age 32～86 years old, 55.7 years old mean age, male 183 examples, female's 217 examples.All patients detect through borne densitometers, and bone density is lower than standard value.
Subjects age distribution as shown in Figure 1
Two, Therapeutic Method:
1 composition:
Pyritum (forging) 100.6g Eupolyphaga Seu Steleophaga 40.2g Pheretima 40.2g Cortex Mori 40.2g
Rhizoma Drynariae (system) 20.1g Radix Dipsaci 20.1g Herba Taxilli 20.1g Radix Angelicae Sinensis 20.1g
Olibanum (system) 40.2g Radix Angelicae Dahuricae 40.2g Flos Carthami 20.1g Myrrha (processed) 40.2g
Radix Et Rhizoma Rhei (system) 12.1g
2 usages: one time 4,2 times on the one.
Three, efficacy assessment standard:
Effective: the average bone density for the treatment of group is significantly greater than the average bone density of matched group.
Effective: the average bone density for the treatment of group is greater than the average bone density of matched group.
Invalid: the average bone density indifference of the average bone density for the treatment of group and matched group.
Four, model case:
1, people from Tiexi District of 47 years old Shenyang City of woods XX female.The right hand 3.4 Phalangeal fracture+osteoporosis, when patient admission, expression is painful, palm redness, heating, pain.The conservative physiotherapy of doctor advised and traditional Chinese medical science reset maneuver, coordinate and take bone strengthening sheet, taking medicine after one week, and symptom is obviously improved.Through CT examination, fracture site healing is good, measures through borne densitometers, and bone density increases.After leaving hospital coordinate eat one the course for the treatment of bone strengthening sheet, patient is clearly better.
2, poplar XX man people from Dadong District of 41 years old Shenyang City.Left Fracture of the distal ulna and radius, osteoporosis, redness, heating, pain when patient admission.The conservative physiotherapy of doctor advised and traditional Chinese medical science reset maneuver, coordinate and take bone strengthening sheet, taking medicine after one week, and symptom is obviously improved.Through CT examination, fracture site healing is good, measures through borne densitometers, and bone density increases.After leaving hospital coordinate eat one the course for the treatment of bone strengthening sheet, patient is clearly better.
3, in the Huanggu District people of 47 years old Shenyang City of X female.Right fracture of scaphoid bone of wrist, osteoporosis, right wrist redness, heating, pain when patient admission.The conservative physiotherapy of doctor advised and traditional Chinese medical science reset maneuver, coordinate and take bone strengthening sheet, taking medicine after one week, and symptom is obviously improved.Through CT examination, fracture site healing is good, measures through borne densitometers, and bone density increases.After leaving hospital coordinate eat one the course for the treatment of bone strengthening sheet, patient is clearly better.
4, Peng XX man people from Tiexi District of 70 years old Shenyang City.Right 7,8 fractures of rib, osteoporosis, right rib redness, heating, pain when patient admission.The conservative physiotherapy of doctor advised and traditional Chinese medical science reset maneuver, coordinate and take bone strengthening sheet, taking medicine after one week, and symptom is obviously improved.Through CT examination, fracture site healing is good, measures through borne densitometers, and bone density increases.After leaving hospital coordinate eat one the course for the treatment of bone strengthening sheet, patient is clearly better.
5, Hu people from Huanggu District of 80 years old Shenyang City of XX female.Left fracture of phalanx of foot, osteoporosis, when patient admission, expression is painful, left foot redness, heating, pain.The conservative physiotherapy of doctor advised and traditional Chinese medical science reset maneuver, coordinate and take bone strengthening sheet, taking medicine after one week, and symptom is obviously improved.Through CT examination, fracture site healing is good, measures through borne densitometers, and bone density increases.After leaving hospital coordinate eat one the course for the treatment of bone strengthening sheet, left foot recovers normal function substantially, bends and stretches the limbs freely, and can be engaged in light physical labor.
6, road XX man people from Huanggu District of 42 years old Shenyang City.Left ulnar fracture, osteoporosis, wound redness, heating, pain when patient admission.The conservative physiotherapy of doctor advised and traditional Chinese medical science reset maneuver, coordinate and take bone strengthening sheet, taking medicine after one week, and symptom is obviously improved.Through CT examination, fracture site healing is good, measures through borne densitometers, and bone density increases.After leaving hospital coordinate eat one the course for the treatment of bone strengthening sheet, patient is clearly better.
7, high XX man people from Huanggu District of 57 years old Shenyang City.Right phalanx fracture, osteoporosis, wound redness, heating, pain when patient admission.The conservative physiotherapy of doctor advised and traditional Chinese medical science reset maneuver, coordinate and take bone strengthening sheet, taking medicine after one week, and symptom is obviously improved.Through CT examination, fracture site healing is good, measures through borne densitometers, and bone density increases.After leaving hospital coordinate eat one the course for the treatment of bone strengthening sheet, patient is clearly better.
8, tight XX female people from Huanggu District of 48 years old Shenyang City.Right phalanx fracture, osteoporosis, when patient admission, expression is painful, wound redness, heating, pain.The conservative physiotherapy of doctor advised and traditional Chinese medical science reset maneuver, coordinate and take bone strengthening sheet, taking medicine after one week, and symptom is obviously improved.Through CT examination, fracture site healing is good, measures through borne densitometers, and bone density increases.After leaving hospital coordinate eat one the course for the treatment of bone strengthening sheet, patient is clearly better.
9, wish people from Dadong District of 25 years old Shenyang City of XX female.The right hand 1.2 Phalangeal fracture+osteoporosis, palm redness, heating, pain when patient admission.The conservative physiotherapy of doctor advised and traditional Chinese medical science reset maneuver, coordinate and take bone strengthening sheet, taking medicine after one week, and symptom is obviously improved.Through CT examination, fracture site healing is good, measures through borne densitometers, and bone density increases.After leaving hospital coordinate eat one the course for the treatment of bone strengthening sheet, the right hand recovers normal function substantially, bends and stretches the limbs freely, and can be engaged in light physical labor.
10, people from Shenhe District of 81 years old Shenyang City of XX female Lee.Right phalanx fracture, osteoporosis, when patient admission, expression is painful, wound redness, heating, pain.The conservative physiotherapy of doctor advised and traditional Chinese medical science reset maneuver, coordinate and take bone strengthening sheet, taking medicine after one week, and symptom is obviously improved.Through CT examination, fracture site healing is good, measures through borne densitometers, and bone density increases.After leaving hospital coordinate eat one the course for the treatment of bone strengthening sheet, patient is clearly better.
Five, therapeutic outcome:
It is the longest 30 weeks that this group case is accepted this law treatment time, the shortest 8 weeks, average 20 weeks.The time of following up a case by regular visits to is the longest 24 months, the shortest 2 months, average 11 months.In 200 all routine subjects, remarkable result is 162 examples; Be effectively 34 examples; 4 invalid examples.Effective percentage 98%, good compliance rate 81%.
Test group medication forward backward averaging bone density contrasts as shown in Figure 2.
Claims (6)
- One kind to be used for the treatment of Liver and kidney deficient, the pharmaceutical composition of waist knee joint unfavorable (osteoporosis), is characterized in that being made up of the crude drug of following weight portion:30～60 parts of 10～20 parts of Radix Angelicae Sinensis of 10～20 parts of Radix Ginseng Rubra of 30～60 parts of Radix Dipsacis of Cornu Cervi Pantotrichum (unhairing) 10～20 parts of Fructus Psoraleaes, 20～40 parts of Cornu Cervi Degelatinatums, 30～60 portions of Concha Ostreaes of 60～120 parts of Radix Rehmanniae Preparata (forging)30～60 parts of 30～60 parts of Fructus Corni of 30～60 parts of Radix Polygoni Multiflori of 20～40 parts of Rhizoma Atractylodis Macrocephalaes of Radix Notoginseng (stir-fry) (system)20～40 parts of 30～60 parts of Pheretimas of Fructus Lycii.
- 2. according to pharmaceutical composition claimed in claim 1, it is characterized in that: the weight portion of each crude drug is:12～36 parts of 4～14 parts of Radix Angelicae Sinensis of 4～14 parts of Radix Ginseng Rubra of 12～36 parts of Radix Dipsacis of Cornu Cervi Pantotrichum (unhairing) 4～14 parts of Fructus Psoraleaes, 8～28 parts of Cornu Cervi Degelatinatums, 12～36 portions of Concha Ostreaes of 16～56 parts of Radix Rehmanniae Preparata (forging)12～36 parts of 12～36 parts of Fructus Corni of 12～36 parts of Radix Polygoni Multiflori of 8～28 parts of Rhizoma Atractylodis Macrocephalaes of Radix Notoginseng (stir-fry) (system)8～28 parts of 12～36 parts of Pheretimas of Fructus Lycii.
- 3. according to pharmaceutical composition claimed in claim 3, wherein the weight portion of each component is:23.7 parts of 47.3 parts of Radix Rehmanniae Preparata of 15.8 parts of Cornu Cervi Degelatinatums of 7.9 parts of Fructus Psoraleaes of Cornu Cervi Pantotrichum (unhairing)23.7 parts of 7.9 parts of Radix Angelicae Sinensis of 7.9 parts of Radix Ginseng Rubra of 23.7 parts of Radix Dipsacis of Concha Ostreae (forging)23.7 parts of 23.7 parts of Fructus Corni of 23.7 parts of Radix Polygoni Multiflori of 15.8 parts of Rhizoma Atractylodis Macrocephalaes of Radix Notoginseng (stir-fry) (system)15.8 parts of 23.7 parts of Pheretimas of Fructus Lycii.
- 4. according to any one pharmaceutical composition described in claim 1,2,3, it is characterized in that: can method of Chinese medicinal routinely be prepared into any conventional oral formulations.
- 5. according to pharmaceutical composition claimed in claim 4, it is characterized in that: described oral formulations is pill, capsule, tablet, powder or granule.
- 6. the arbitrary pharmaceutical composition described in claim 1～5 is deficient at preparation treatment Liver and kidney, the application in waist knee joint unfavorable (osteoporosis) medicine.
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| CN201310137738.8A CN104107266A (en) | 2013-04-20 | 2013-04-20 | Bone-strengthening tablet |
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| CN201310137738.8A CN104107266A (en) | 2013-04-20 | 2013-04-20 | Bone-strengthening tablet |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105768094A (en) * | 2016-04-19 | 2016-07-20 | 长春康彼达科技有限公司 | Health-care food for increasing bone density and making method thereof |
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| CN1328841A (en) * | 2001-06-18 | 2002-01-02 | 佛山市中医院 | Medicine for preventing and curing asteoporosis and promoting union and its production method |
| CN1385209A (en) * | 2002-06-05 | 2002-12-18 | 葛运清 | Gukang powder medicine for treating bone disease |
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2013
- 2013-04-20 CN CN201310137738.8A patent/CN104107266A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1328841A (en) * | 2001-06-18 | 2002-01-02 | 佛山市中医院 | Medicine for preventing and curing asteoporosis and promoting union and its production method |
| CN1385209A (en) * | 2002-06-05 | 2002-12-18 | 葛运清 | Gukang powder medicine for treating bone disease |
Non-Patent Citations (1)
| Title |
|---|
| 丁梅等: "壮骨片治疗骨质疏松", 《辽宁中医药大学学报》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105768094A (en) * | 2016-04-19 | 2016-07-20 | 长春康彼达科技有限公司 | Health-care food for increasing bone density and making method thereof |
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