CN105362837A - Oral disinfecting liquid for nursing - Google Patents

Oral disinfecting liquid for nursing Download PDF

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Publication number
CN105362837A
CN105362837A CN201510764754.9A CN201510764754A CN105362837A CN 105362837 A CN105362837 A CN 105362837A CN 201510764754 A CN201510764754 A CN 201510764754A CN 105362837 A CN105362837 A CN 105362837A
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CN
China
Prior art keywords
parts
disinfecting liquid
disinfecting
cortex phellodendri
oral
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Pending
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CN201510764754.9A
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Chinese (zh)
Inventor
姚永芳
田静
邢艳丽
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Jilin University
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Jilin University
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Priority to CN201510764754.9A priority Critical patent/CN105362837A/en
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The invention discloses oral disinfecting liquid for nursing. The disinfecting liquid consists of the following ingredients in parts by weight: 11-16 parts of ethanol, 5-11 parts of sorbitol, 6-10 parts of tea polyphenol, 7-9 parts of glycyrrhizin, 1-2 parts of rhizoma smilacis glabrae, 1-2 parts of fructus cnidii, 1-2 parts of honeysuckle, 3-5 parts of radix sophorae flavescentis, 3-5 parts of cortex phellodendri, 3-5 parts of radix gentianae and 100-150 parts of de-ionized water. Compared with the prior art, the disinfecting liquid disclosed by the invention has the following beneficial effects: (1) the disinfecting liquid is significant in sterilizing and disinfecting effects on escherichia coli, staphylococcus aureus, candida albicans and the like, and a killing rate within 1min reaches 100%; (2) the disinfecting liquid, which is subject to a traditional Chinese medicine formula, is non-toxic, non-irritant, anti-corrosive and faint in fragrance; and (3) the disinfecting liquid is broad in application scope and is suitable for various fields; and the disinfecting liquid is suitable for disinfecting and sterilizing oral cavities of people at all ages, in particular removing bad breath in oral cavity with the most ideal effect.

Description

A kind of nursing oral-cavity disinfectant
Technical field
The present invention relates to oral disinfecting treatment class drug world, be specifically related to a kind of nursing oral-cavity disinfectant.
Background technology
In the process of dental diagnostic, need patient to use oral-cavity disinfectant to gargle to carry out preliminarily pasteurized to oral cavity, existing oral-cavity disinfectant is on the market chemical agent mostly, these chemical agents have side effect mostly, temporarily yet there are no a kind of Traditional Chinese medicine disinfectant that can sterilize and can treat.
Summary of the invention
The object of the invention is to the defect overcoming prior art, provide one can antimicrobial therapy, the nursing oral-cavity disinfectant that with the addition of Chinese medicine preparation had no side effect again.
To achieve these goals, technical scheme of the present invention is as follows:
A kind of nursing oral-cavity disinfectant, comprises the composition of following weight content: ethanol 11-16 parts, sorbitol 5-11 parts, tea polyphenols 6-10 parts, glycyrrhizin 7-9 parts, Rhizoma Smilacis Glabrae 1-2 parts, Fructus Cnidii 1-2 parts, Flos Lonicerae 1-2 parts, Radix Sophorae Flavescentis 3-5 parts, Cortex Phellodendri 3-5 parts, Radix Gentianae 3-5 parts, deionized water 100-150 parts.
Preferably, Rhizoma Smilacis Glabrae, Fructus Cnidii, Flos Lonicerae, Radix Sophorae Flavescentis, Cortex Phellodendri, Radix Gentianae are pulverized respectively, cross 20 mesh sieves, in ground product, add all the other batchings respectively stir, filter in the filter after leaving standstill, last filling and sealing.
Preferably, the composition of following weight content is comprised: ethanol 11 parts, sorbitol 5 parts, tea polyphenols 6 parts, glycyrrhizin 7 parts, Rhizoma Smilacis Glabrae 1 part, Fructus Cnidii 1 part, Flos Lonicerae 1 part, Radix Sophorae Flavescentis 3 parts, Cortex Phellodendri 3 parts, Radix Gentianae 3 parts, deionized water 100 parts.
Preferably, the composition of following weight content is comprised: ethanol 16 parts, sorbitol 11 parts, tea polyphenols 10 parts, glycyrrhizin 9 parts, Rhizoma Smilacis Glabrae 2 parts, Fructus Cnidii 2 parts, Flos Lonicerae 2 parts, Radix Sophorae Flavescentis 5 parts, Cortex Phellodendri 5 parts, Radix Gentianae 5 parts, deionized water 150 parts.
Preferably, the composition of following weight content is comprised: ethanol 14 parts, sorbitol 6 parts, tea polyphenols 8 parts, glycyrrhizin 8 parts, Rhizoma Smilacis Glabrae 1 part, Fructus Cnidii 1 part, Flos Lonicerae 1 part, Radix Sophorae Flavescentis 4 parts, Cortex Phellodendri 4 parts, Radix Gentianae 4 parts, deionized water 120 parts.
Tea polyphenols scavenging free radicals in the present invention, glycyrrhizin prevents tartar from producing, and plays sweeting agent effect, and sorbitol plays mediation and moisture-keeping function, and ethanol plays solvent action, and distilled water is diluent.
Rhizoma Smilacis Glabrae removing damp-heat, let out turbid removing toxic substances, easing joint movement, can the damp and hot stranguria with turbid discharge of external prevention and therapy, leukorrhagia, carbuncle, scrofula, scabies, syphilis and limbs contracture, bones and muscles pain etc. caused by mercurialism, modern pharmacological research shows, Rhizoma Smilacis Glabrae all has obvious bacteriostasis to staphylococcus, A type and group B streptococcus etc.
Fructus Cnidii removing dampness and killing parasites, dispelling wind for relieving itching, can decocting liquid outer to swell and ache for pudendal pruritus, the treatment of rheumatic arthralgia, eczema scabies and prevention, the in vitro tests display of the osthole contained by it, bergapton and isopimpinellin, have strong activity to staphylococcus aureus, bacillus pyocyaneus, dermatophytosis etc., the xanthotoxol contained by it also has stronger antiinflammatory and analgesic effect.
Radix Gentianae water logging agent has inhibitory action in various degree to multiple pathogenic dermatophytes and bacillus pyocyaneus, dysentery bacterium, staphylococcus aureus etc., its bitter in the mouth is cold in nature, heat clearing and damp drying, can externally applied anti-inflammation antipruritic, the gentiopicrin in addition contained by Radix Gentianae also has higher toxicity to plasmodium.
The effective ingredient of Cortex Phellodendri is mainly the flavones ingredient such as the alkaloids such as berberine and flavone Radix Hyperici Monogyni (Herba Hyperici Monogyni), except having stronger inhibitory action to multiple pathogenic dermatophytess such as the antibacterial such as staphylococcus aureus, streptococcus pneumoniae and acrothesium floccosums, also has effect of antiallergic action simultaneously, in addition, Cortex Phellodendri has heat clearing and damp drying, and pathogenic fire purging removes steams, effect of detoxification sore treatment, decocting liquid washout can be used for sore swollen toxin, the treatment of skin eczema pruritus etc. and prevention.
The main extract component of Radix Sophorae Flavescentis is biological alkali components, and this composition all has obvious bacteriostasis to escherichia coli, staphylococcus aureus, dysentery bacterium and multiple pathogenic dermatophytes; Simultaneously because of effect of its heat clearing and damp drying, parasite killing, normal decocting liquid external, for treatment and the prevention of pudendal pruritus, scabies, leprosy, skin pruritus, noxious dampness skin infection.
Flos Lonicerae have resisting pathogenic microbes, antiinflammatory, antipyretic, protect the liver, antifertility, hemostasis, immunomodulating, the effect such as blood fat reducing, Flos Lonicerae all has certain inhibitory action to various pathogens, the ethanol of stem and leaf of Flos Lonicerae and acetone extract can obviously grow by Antifungi, also have inhibitory action to multiple virus.
Compared with prior art, there is following beneficial effect in the present invention: (1) sterilization effect is remarkable, and to escherichia coli, staphylococcus aureus, Candida albicans etc., within one minute, killing rate can reach 100%; (2) owing to adopting Chinese medicine formula, nontoxic, non-stimulated, non-corrosiveness, abnormal smells from the patient delicate fragrance; (3) scope of application is wide, is applicable to every field, the oral disinfecting sterilization of various age groups, especially ideal to excision halitosis.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further details.
Embodiment 1:
Take Poria 1kg, Fructus Cnidii 1kg, Flos Lonicerae 1kg, Radix Sophorae Flavescentis 4kg, Cortex Phellodendri 4kg, Radix Gentianae 4kg, be pulverized and mixed evenly respectively, cross 20 mesh sieves, add water 120L, decocts after 1 hour and filter, then the 120L that adds water, and decocts after 1 hour and filter.Merge twice decoction liquor, be concentrated into d=1.8g/ml, obtain Chinese medicine extraction liquid.
Under agitation slowly add ethanol 11L successively, sorbitol 5L, tea polyphenols 6L, glycyrrhizin 7L, stirs, and filters in the filter, last filling and sealing after leaving standstill.
Embodiment 2:
Take Poria 2kg, Fructus Cnidii 2kg, Flos Lonicerae 2kg, Radix Sophorae Flavescentis 5kg, Cortex Phellodendri 5kg, Radix Gentianae 5kg, be pulverized and mixed evenly respectively, cross 20 mesh sieves, add water 150L, decocts after 1 hour and filter, then the 150L that adds water, and decocts after 1 hour and filter.Merge twice decoction liquor, be concentrated into d=1.8g/ml, obtain Chinese medicine extraction liquid.
Under agitation slowly add ethanol 16L successively, sorbitol 11L, tea polyphenols 10L, glycyrrhizin 9L, stirs, and filters in the filter, last filling and sealing after leaving standstill.
Embodiment 3:
Take Poria 1kg, Fructus Cnidii 1kg, Flos Lonicerae 1kg, Radix Sophorae Flavescentis 3kg, Cortex Phellodendri 3kg, Radix Gentianae 3kg, be pulverized and mixed evenly respectively, cross 20 mesh sieves, add water 150L, decocts after 1 hour and filter, then the 100L that adds water, and decocts after 1 hour and filter.Merge twice decoction liquor, be concentrated into d=1.8g/ml, obtain Chinese medicine extraction liquid.
Under agitation slowly add ethanol 11L successively, sorbitol 5L, tea polyphenols 6L, glycyrrhizin 7L, stirs, and filters in the filter, last filling and sealing after leaving standstill.
Tea polyphenols scavenging free radicals in the present invention, glycyrrhizin prevents tartar from producing, and plays sweeting agent effect, and sorbitol plays mediation and moisture-keeping function, and ethanol plays solvent action, and distilled water is diluent.
Rhizoma Smilacis Glabrae removing damp-heat, let out turbid removing toxic substances, easing joint movement, can the damp and hot stranguria with turbid discharge of external prevention and therapy, leukorrhagia, carbuncle, scrofula, scabies, syphilis and limbs contracture, bones and muscles pain etc. caused by mercurialism, modern pharmacological research shows, Rhizoma Smilacis Glabrae all has obvious bacteriostasis to staphylococcus, A type and group B streptococcus etc.
Fructus Cnidii removing dampness and killing parasites, dispelling wind for relieving itching, can decocting liquid outer to swell and ache for pudendal pruritus, the treatment of rheumatic arthralgia, eczema scabies and prevention, the in vitro tests display of the osthole contained by it, bergapton and isopimpinellin, have strong activity to staphylococcus aureus, bacillus pyocyaneus, dermatophytosis etc., the xanthotoxol contained by it also has stronger antiinflammatory and analgesic effect.
Radix Gentianae water logging agent has inhibitory action in various degree to multiple pathogenic dermatophytes and bacillus pyocyaneus, dysentery bacterium, staphylococcus aureus etc., its bitter in the mouth is cold in nature, heat clearing and damp drying, can externally applied anti-inflammation antipruritic, the gentiopicrin in addition contained by Radix Gentianae also has higher toxicity to plasmodium.
The effective ingredient of Cortex Phellodendri is mainly the flavones ingredient such as the alkaloids such as berberine and flavone Radix Hyperici Monogyni (Herba Hyperici Monogyni), except having stronger inhibitory action to multiple pathogenic dermatophytess such as the antibacterial such as staphylococcus aureus, streptococcus pneumoniae and acrothesium floccosums, also has effect of antiallergic action simultaneously, in addition, Cortex Phellodendri has heat clearing and damp drying, and pathogenic fire purging removes steams, effect of detoxification sore treatment, decocting liquid washout can be used for sore swollen toxin, the treatment of skin eczema pruritus etc. and prevention.
The main extract component of Radix Sophorae Flavescentis is biological alkali components, and this composition all has obvious bacteriostasis to escherichia coli, staphylococcus aureus, dysentery bacterium and multiple pathogenic dermatophytes; Simultaneously because of effect of its heat clearing and damp drying, parasite killing, normal decocting liquid external, for treatment and the prevention of pudendal pruritus, scabies, leprosy, skin pruritus, noxious dampness skin infection.
Flos Lonicerae have resisting pathogenic microbes, antiinflammatory, antipyretic, protect the liver, antifertility, hemostasis, immunomodulating, the effect such as blood fat reducing, Flos Lonicerae all has certain inhibitory action to various pathogens, the ethanol of stem and leaf of Flos Lonicerae and acetone extract can obviously grow by Antifungi, also have inhibitory action to multiple virus.

Claims (5)

1. a nursing oral-cavity disinfectant, is characterized in that: the composition comprising following weight content: ethanol 11-16 parts, sorbitol 5-11 parts, tea polyphenols 6-10 parts, glycyrrhizin 7-9 parts, Rhizoma Smilacis Glabrae 1-2 parts, Fructus Cnidii 1-2 parts, Flos Lonicerae 1-2 parts, Radix Sophorae Flavescentis 3-5 parts, Cortex Phellodendri 3-5 parts, Radix Gentianae 3-5 parts, deionized water 100-150 parts.
2. nursing oral-cavity disinfectant according to claim 1, it is characterized in that: Rhizoma Smilacis Glabrae, Fructus Cnidii, Flos Lonicerae, Radix Sophorae Flavescentis, Cortex Phellodendri, Radix Gentianae are pulverized respectively, cross 20 mesh sieves, in ground product, add all the other batchings respectively stir, filter in the filter after leaving standstill, last filling and sealing.
3. nursing oral-cavity disinfectant according to claim 1, is characterized in that: the composition comprising following weight content: ethanol 11 parts, sorbitol 5 parts, tea polyphenols 6 parts, glycyrrhizin 7 parts, Rhizoma Smilacis Glabrae 1 part, Fructus Cnidii 1 part, Flos Lonicerae 1 part, Radix Sophorae Flavescentis 3 parts, Cortex Phellodendri 3 parts, Radix Gentianae 3 parts, deionized water 100 parts.
4. nursing oral-cavity disinfectant according to claim 1, is characterized in that: the composition comprising following weight content: ethanol 16 parts, sorbitol 11 parts, tea polyphenols 10 parts, glycyrrhizin 9 parts, Rhizoma Smilacis Glabrae 2 parts, Fructus Cnidii 2 parts, Flos Lonicerae 2 parts, Radix Sophorae Flavescentis 5 parts, Cortex Phellodendri 5 parts, Radix Gentianae 5 parts, deionized water 150 parts.
5. nursing oral-cavity disinfectant according to claim 1, is characterized in that: the composition comprising following weight content: ethanol 14 parts, sorbitol 6 parts, tea polyphenols 8 parts, glycyrrhizin 8 parts, Rhizoma Smilacis Glabrae 1 part, Fructus Cnidii 1 part, Flos Lonicerae 1 part, Radix Sophorae Flavescentis 4 parts, Cortex Phellodendri 4 parts, Radix Gentianae 4 parts, deionized water 120 parts.
CN201510764754.9A 2015-11-10 2015-11-10 Oral disinfecting liquid for nursing Pending CN105362837A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108159299A (en) * 2018-01-24 2018-06-15 合肥华盖生物科技有限公司 A kind of safe quick-acting cavity disinfection spray and preparation method thereof
CN111821397A (en) * 2020-06-08 2020-10-27 晒欧国际生物科技(广州)有限公司 Environment-friendly rapid bactericide

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102429850A (en) * 2011-12-30 2012-05-02 山西振东制药股份有限公司 Traditional Chinese medicine antibacterial and nourishing bath foam and preparation method thereof
CN102772764A (en) * 2012-07-19 2012-11-14 张吉玲 Nursing traditional Chinese medicine disinfectant and preparation method
CN103655525A (en) * 2013-11-14 2014-03-26 青岛安信医疗器械有限公司 Oral disinfectant

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102429850A (en) * 2011-12-30 2012-05-02 山西振东制药股份有限公司 Traditional Chinese medicine antibacterial and nourishing bath foam and preparation method thereof
CN102772764A (en) * 2012-07-19 2012-11-14 张吉玲 Nursing traditional Chinese medicine disinfectant and preparation method
CN103655525A (en) * 2013-11-14 2014-03-26 青岛安信医疗器械有限公司 Oral disinfectant

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108159299A (en) * 2018-01-24 2018-06-15 合肥华盖生物科技有限公司 A kind of safe quick-acting cavity disinfection spray and preparation method thereof
CN111821397A (en) * 2020-06-08 2020-10-27 晒欧国际生物科技(广州)有限公司 Environment-friendly rapid bactericide

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