CN105663819A

CN105663819A - Externally applied traditional Chinese medicine preparation for treating bromhidrosis and preparation method

Info

Publication number: CN105663819A
Application number: CN201610062563.2A
Authority: CN
Inventors: 不公告发明人
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-01-29
Filing date: 2016-01-29
Publication date: 2016-06-15

Abstract

The invention discloses an externally applied traditional Chinese medicine preparation for treating bromhidrosis. The externally applied traditional Chinese medicine preparation is prepared from raw materials in parts by weight as follows: 8-13 parts of lophatherum herbs, 5-11 parts of Japanese flowering fern rhizomes, 7-12 parts of Chinese dicliptera herbs, 6-11 parts of Chinese yams, 4-8 parts of figs, 8-12 parts of Japanese butterbur rhizomes, 6-13 parts of flowers of Aglaia odorata, 9-12 parts of Tokyo violet herbs, 5-12 parts of longan pits, 7-13 parts of all-grass of annual saltmarsh aster, 4-9 parts of semi-pinnated brake herbs, 3-7 parts of feather cockscomb seeds and 6-10 parts of moellendorf's spidemoss herbs. The preparation has the excellent effects as follows: composition of a prescription is analyzed by using the theory of traditional Chinese medicine, and according to research results about physicochemical properties and pharmacological actions of components of all herbal medicines in the prescription, a reasonable and effective preparation method of active components is obtained through research; the obtained preparation can have effects of dredging channels, clearing endogenetic toxins and damp-heat and thoroughly eliminating the source of the bromhidrosis root except for apparent sweating checking and deodorization effects, so that both symptoms and root causes are treated.

Description

A kind of traditional Chinese medicine for outer use and method for making curing underarm odor

Technical field

The present invention relates to traditional Chinese medicine field, particularly relate to a kind of traditional Chinese medicine for outer use and the method for making of curing underarm odor.

Background technology

Underarm odor is commonly called as " body odour ", is the secretory product produced by armpit large sudoriferous gland, through bacterial degradation after excreting, produces a kind of unpleasant smell, and by endocrinologic effects, underarm odor is many in pubescence, alleviates or disappear to old age. Part has family history, it is possible to relevant with heredity. The sickness rate of underarm odor is variant with the difference of individual and hygienic habit, and its degree difference changes to some extent with season and weather. This card severe patient affects the contacts of patient, causes psychological burden, even affects daily live and work.

The occurrent time of underarm odor is many after the Paederus fuscipes Curtis phase, and women is boy student's slightly morning relatively. Its smelly mechanism is because patient's axillary apocrine is too abundant, supersecretion sweat, the big sweat just discharging skin surface is oyster white, aseptic tasteless, soon by the decomposition of moist position bacterium (staphylococcus epidermidis, gram negative bacillus etc.) of armpit, typical acrid odors is sent. The acrid odors system of underarm odor by caused by the unsaturated side chain lipid acid of six carbon to ten carbon, the mainly trans-2 methyl caproic acid of 3-and the male ketenes of 50-.

The traditional Chinese medical science is thought: " underarm odor person, oxious gas goes out from oxter, and such as fox offensive smell of mutton, making us can not be close, popular name body odour. Underarm odor patient, it is as thin in pin that its oxter must have hair empty, namely goes out dirty place, and Er Neibi has oil wet. " underarm odor is many relevant with congenital natural endowment, report in congenital, follow the gas that father and mother oxter is foul, fumigate in outward, go out from oxter; Or the product because of the pungent savoury of overfeeding, cause retention of damp-heat in the interior.

The method for the treatment of body odour is numerous at present, can be divided into two big class, pharmacological agent and operative treatments by the method for the treatment of. Existing medicine can only play alleviation, can not reach the object of radical cure, and patient skin is easily irritated, scratchy even blackening unbearably, and side effect is big, and HUMAN HEALTH is unfavorable; Operation method mostly is traditional operation, laser, microwave etc., and area is big, and wound is dark, recovers slow, and has certain danger, and patient cannot accept, and recurrence rate height, and curative effect owes desirable.

Application publication number CN104352972A(application number 201410618885.1) Chinese invention patent document disclose a kind of Chinese medicine preparation treating underarm odor, be prepared from by the raw material of following weight part number: Wu Chia Pee 5-10 part, celestial being's Lysimachia christinae Hance 5-11 part, root tuber of aromatic turmeric 6-11 part, bitter 6-12 part, snake king grass 4-8 part, bighead atractylodes rhizome 4-9 part, root bark of tree peony 4-10 part, Vegetable Sponge of Luffa 5-10 part.Application publication number CN104623375A(application number 201510072239.4) Chinese invention patent document disclose a kind of Chinese medicine composition and its preparation method for the treatment of underarm odor, be prepared from by the raw material of following weight part number: coptis 8-13 part, lavandula angustifolia 6-12 part, meadow pine 4-10 part, Fruit of Black Nightshade 5-11 part, Rhizoma Typhonii 3-9 part, Tender Catchweed Bedstraw Herb 4-8 part, leaf of bamboo 3-6 part, camphor 2-6 part, Northern Dutchmanspipe Vine 4-10 part. Application publication number CN104027776A(application number 201410288134.8) Chinese invention patent document disclose a kind of Chinese medicine treating body odour, be made up of the raw material of following weight part: perilla seed 4-10 part, tuber of pinellia 3-9 part, ginger 3-9 part, lime 1-3 part, root of Dahurain angelica 3-9 part, peppermint 2-6 part, Yanhusuo 3-9 part, MEIHUA BINGPIAN 0.1-0.3 part, yellow lead oxide's 0.1-0.5 part, potato 10-20 part, Leaf of Tungoiltree 10-20 part, rheum officinale 3-9 part, Slender Dutchmanspipe Root 1-2 part, star anise 2-6 part, spider 0.3-1 part.

Although at present the Chinese medicine medicine for the treatment of underarm odor is a lot, but exist medical expense height, effective slow, curative effect is undesirable, it is difficult to the thoroughly defect such as elimination.

Summary of the invention

For the deficiencies in the prior art, it is an object of the invention to provide the traditional Chinese medicine for outer use of a kind of easy to prepare, compatibility is simple, curative effect is definite treatment underarm odor and preparation method. This Chinese medicine preparation curative ratio height, gentleness does not stimulate.

The technical scheme of the present invention is:

Cure a traditional Chinese medicine for outer use for underarm odor, it is prepared from by following bulk drugs, be weight part: Herba Lophatheri 8-13; JapaneseFloweringFernRhizome 5-11; Herba Diclipterae Chinensis 7-12; Chinese yam 6-11; Fructus Fici 4-8; Rhizome of Japanese Butterbur 8-12; Flower of Chu-lan Tree flower 6-13; Philippine Violet Herb 9-12; Seed of Arillus Longan 5-12; Auspicious even grass 7-13; Semipinnated Brake Herb 4-9; Semen Celosiae 3-7; Moellendorfs Spidemoss Herb 6-10.

In preferred scheme, Herba Lophatheri 9.5-11.5; JapaneseFloweringFernRhizome 7-9; Herba Diclipterae Chinensis 8.5-10.5; Chinese yam 7.5-9.5; Fructus Fici 5-7; Rhizome of Japanese Butterbur 9-11; Flower of Chu-lan Tree flower 8-11; Philippine Violet Herb 10-11; Seed of Arillus Longan 7-10; Auspicious even grass 9-11; Semipinnated Brake Herb 5-8; Semen Celosiae 4-6; Moellendorfs Spidemoss Herb 7-9.

More preferably, Herba Lophatheri 10.5; JapaneseFloweringFernRhizome 8; Herba Diclipterae Chinensis 9.5; Chinese yam 8.5; Fructus Fici 6; Rhizome of Japanese Butterbur 10; Flower of Chu-lan Tree spends 9.5; Philippine Violet Herb 10.5; Seed of Arillus Longan 8.5; Auspicious even grass 10; Semipinnated Brake Herb 6.5; Semen Celosiae 5; Moellendorfs Spidemoss Herb 8.

Curing a preparation method for the spray agent of the traditional Chinese medicine for outer use of underarm odor, step is as follows:

(1) date that seed of Arillus Longan is placed in stoning wraps up tight, is placed in hot sand, and intense fire heats, and turns over fast to fry and heaves to fructus corni, and slightly focal spot, takes out, remove jujube, for subsequent use;

(2) Semen Celosiae and Philippine Violet Herb mixing, the ginger juice adding 0.85-1.35 times amount is mixed thoroughly (ginger juice preferably adding 1.1 times amount is mixed thoroughly), vexed 24-40 minute (preferably vexed 32 minutes), then being placed in steamer, supreme vapour is steamed in big fire, takes out, smashing juice, juice filters, for subsequent use;

(3) seed of Arillus Longan and Moellendorfs Spidemoss Herb, Semipinnated Brake Herb, Herba Lophatheri and JapaneseFloweringFernRhizome after step (1) being concocted together grind powder, the alcohol steep adding 60% 1-3 days (alcohol steep preferably adding 60% 2 days), collect vat liquor, filter, and filtrate is for subsequent use;

(4) by Herba Diclipterae Chinensis, Chinese yam, Fructus Fici, Rhizome of Japanese Butterbur, Flower of Chu-lan Tree flower and auspicious even grass mixing, it is placed in medicine pot, adding clear water and do not have powder 3-5cm, slow fire boiling twice, first time decocts and boils 36-50 minute (preferably first time decocts and boils 43 minutes), second time is decocted and is boiled 18-30 minute (preferably second time is decocted and boiled 24 minutes), merging twice decocting liquid, filter, filtrate merges with step (2) and (3) gained filtrate, obtain mixing solutions, for subsequent use;

(5) step (4) gained mixing solutions being evaporated to the 1/3 of original volume, through millipore filtration membrane filtration, add other auxiliary material, mixed even, bottling, to obtain final product.

The preparation method of the spray agent of above-mentioned a kind of traditional Chinese medicine for outer use curing underarm odor, it is preferable that scheme be, auxiliary material described in step (5) to be massfraction be 0.73% borneol and massfraction be the primary ammonium phosphate of 0.35%.

Curing a preparation method for the ointment of the traditional Chinese medicine for outer use of underarm odor, step is as follows:

(1) it is placed in round-bottomed flask by broken for Flower of Chu-lan Tree pollen, adds the distilled water immersion 2-5 hour distilled water immersion of 20 times amount (preferably add 3.5 hours) of 15-25 times amount, then extract volatile oil according to vapor extraction method, for subsequent use;

(2) surplus stock medicine is fully dry, smash into meal to pieces, load in penetrating bag, add the distilled water slow fire boiling twice distilled water slow fire boiling of times amount (preferably add 10 twice) of 8-12 times amount, each each decocting is boiled 38-56 minute (preferred each each decocting boils 47 minutes), merge twice decocting liquid, filter, filtrate concentrates to liquid than being 1:1.7, adding ethanol makes alcohol content be 50%, leave standstill 7-11 hour (preferably leaving standstill 9 hours), filter, reclaim ethanol, concentrating under reduced pressure becomes medicinal extract, add step (1) gained volatile oil, mixed even, sealing, obtain Chinese medical concrete, for subsequent use,

(3) Vaseline (preferably getting the Vaseline of 2.3 times of Chinese medical concrete amounts) of 1.6-3.0 times of Chinese medical concrete amount, the sodium lauryl sulphate (preferably the sodium lauryl sulphate of 0.2 times of Chinese medical concrete amount) of 0.1-0.3 times of Chinese medical concrete amount and the distilled water (preferably the distilled water of 8 times of Chinese medical concrete amounts) of 6-10 times of Chinese medical concrete amount is got, mixing, stirring in water bath melts, obtained creamy base, for subsequent use;

(4) joining in step (2) gained Chinese medical concrete by step (3) gained creamy base, stir evenly, encapsulation, to obtain final product.

The preparation method of the ointment of above-mentioned a kind of traditional Chinese medicine for outer use curing underarm odor, it is preferable that scheme be that the temperature of step (3) water-bath is 65-85 DEG C (temperature of preferred water-bath is 70-80 DEG C, and the temperature of water-bath more preferably is 75 DEG C).

Curing a preparation method for the pulvis of the traditional Chinese medicine for outer use of underarm odor, step is as follows:

(2) Chinese yam cuts thin slice, add light-coloured vinegar and soak 2-5 hour (preferably add light-coloured vinegar and soak 3.5 hours), take out, thermostatic drying chamber together it is placed in Rhizome of Japanese Butterbur, Herba Diclipterae Chinensis and Semipinnated Brake Herb, in 78-90 DEG C dry 20-35 minute (being preferable over 84 DEG C of dryings 28 minutes), then adjust the temperature to 52-66 DEG C dry 1.5-4.5 hour (preferably adjusting the temperature to 60 DEG C of dryings 3 hours), take out, fine powder together it is ground into the seed of Arillus Longan after step (1) processes, for subsequent use;

(3) surplus stock medicine is placed in frying pan, boiling twice, first time adds the clear water (preferably the clear water of the first time times amount that adds 13.5) of 12-15 times amount, slow fire boiling 50 minutes, second time adds the clear water (preferably the clear water of the second time times amount that adds 7.5) of 6-9 times amount, slow fire boiling 38 minutes, merges twice decocting liquid, filters, filtrate decompression concentrate to 80 DEG C of relative densities be the thick cream of 1.30-1.33, spraying dry, get dry extract powder, for subsequent use;

(4) step (2) gained fine powder and step (3) gained dried cream powder being mixed, sieve, sterile packaged, to obtain final product.

The preparation method of the pulvis of above-mentioned a kind of traditional Chinese medicine for outer use curing underarm odor, it is preferable that scheme be that step (4) is crossed 45-85 order sieve (preferred cross 55-75 order sieve, mistake 65 order sieve more preferably).

Curing a preparation method for the vina of the traditional Chinese medicine for outer use of underarm odor, step is as follows:

(2) it is placed in round-bottomed flask by broken for Flower of Chu-lan Tree pollen, adds the distilled water immersion 2-5 hour distilled water immersion of 20 times amount (preferably add 3.5 hours) of 15-25 times amount, then according to extraction by steam distillation volatile oil, for subsequent use;

(3) surplus stock medicine is fully dry, seed of Arillus Longan after processing with step (1) together pulverizes into fine powder, loads in the penetrating bag of Chinese medicine, adds white wine, sealing is soaked 5-9 days (preferably sealing is soaked 7 days), jolting twice every day period, filters, and filtrate decompression concentrates to medicinal liquor than being 1:3, add step (2) gained volatile oil, mixed even, sterilizing encapsulates, and to obtain final product.

The pharmacology of the present invention's main Chinese medicine material used is as follows:

Herba Lophatheri: base is former: be the full grass of grass Herba Lophatheri. Chemical Composition: stem, leaf are containing triterpenoid: Arundoin, print Cylindrin, taraxerol and friedelin. Pharmacological action: 1. refrigeration function; 2. diuretic properties. Nature and flavor: sweet light, cold. Gui Jing: 1. " book on Chinese herbal medicine is new again ": " enter the heart, kidney two warp. " 2. " book on Chinese herbal medicine brief points ": " few the moon of starting with, yin channel of fainting. " function cures mainly: clearing away the heart-fire, except dysphoria with smothery sensation, diuresis. Controlling pyreticosis thirsty, vexed, red urine is puckery, drenches turbid, aphthous stomatitis tongue boil, swelling and aching of gum.

JapaneseFloweringFernRhizome: base is former: be rhizome and the petiole residue of Osmundaceae plant osmund. Chemical Composition: JapaneseFloweringFernRhizome rhizome is containing dryocrassin and multiple lactone composition: osmund lactone, 5-hydroxyl-2-hexenoic acid-4-lactone, 5-hydroxycaproic acid-4-lactone, 3-hydroxycaproic acid-5-lactone, glucosyl group osmund lactone, the two different glucosyl group osmund lactones of hydrogen, 2-deoxidation-2-ribopyranose lactone. Also containing class sorbic oil glucoside, 5-hydroxyl-3-(β-D-glucopyra glycosyloxy) methyl caproate, voitol-β-D-glucopyanoside, 5 hydroxymethyl 2 furaldehyde, glycerine, succsinic acid, point leaf soil China fir sterone A, ecdysterone, ecdysone and polysaccharide. Pharmacological action: 1. anthelmintic action: when the rhizome of JapaneseFloweringFernRhizome and the decoction of petiole base are diluted to 16% concentration, external have suppression in various degree and relexation to ascaris suum head section, the decoction of 50%-60% is to overall ascaris suum effect after 2-6 hour, and the activity of ascaris suum is in suppression in various degree. Expeling human body intestines worm is had better curative effect by osmund extract. 2. the JapaneseFloweringFernRhizome aqueous extract of antivirus action: 1g/ml can resist adenovirus type III (Ad3) to the attack of the HeLa monolayer cell cultivated after diluting 320 times, has stronger anti-Ad3 active; Herpes simplex virus I-type can be resisted to the attack of liver cancer cell (Hep-2 cell). 3. the impact that blood is solidifying: to the oral osmund aqueous extract 11.1g/kg of rabbit, every day 1 time, totally 4 times, rabbit prothrombin time can be shortened. 100% osmund decoction can obviously shorten the clotting time exempted from. Osmund extract has the effect showing and suppressing blood solidifying. Nature and flavor: bitter; Micro-cold; Slightly poisonous. Gui Jing: spleen; Stomach warp. Function cures mainly: clearing heat and detoxicating; Dissolving stasis and hemostasis; Kill worm. Main flow sense; Epidemic meningitis; Encephalitis; Parotitis; Carbuncle pyogenic infections from tumour or sore; Measles; Varicella; Dysentery; Spit blood; Bleeding from five sense organs or subcutaneous tissue; Have blood in stool; Uterine bleeding; Under band; Pinworm; Tapeworm; The intestinal parasitical diseases such as hookworm.

Herba Diclipterae Chinensis: base is former: be the full grass of acanthaceous plant Herba Diclipterae Chinensis.Nature and flavor: taste is sweet; Micro-hardship; Cold in nature. Gui Jing: the thoughts of returning home; Liver; Lung channel. Function cures mainly: heat-clearing; Cool blood; Profit is wet; Removing toxic substances. Main cold, fever; Pyreticosis sends out spot; Tell bleeding from five sense organs or subcutaneous tissue; Have blood in stool; Hematuria; Uterine bleeding; Cough due to lung-heat; Swelling and pain in the throat; The hot hot eyes of liver; Infantile convulsion; Dribbling urination; Under band; Zoster; Carbuncle swells malignant boil furuncle; Snake lyssodexis.

Chinese yam: base is former: this product is the dry rhizome of Dioscoreaceae plant Chinese yam. Nature and flavor: sweet are flat. Gui Jing: return spleen, lung, kidney channel. Effect: tonifying spleen nourishing the stomach, benefit of promoting the production of body fluid lung, the puckery essence of kidney tonifying. Curing mainly: few for insufficiency of the spleen food, chronic diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to deficiency of the kidney, and under band, frequent micturition, abnormal heat is quenched one's thirst. Rhizoma Dioscoreae (parched with bran) tonifying spleen stomach invigorating. Few for insufficiency of the spleen food, loose stool of having loose bowels, leukorrhagia.

Fructus Fici: base is former: be the dry holder of moraceae plants Fructus Fici. Pharmacological action: 1, Fructus Fici is containing abundant nutritive ingredient, edible. When constipation, can be used as food laxative. 2, the material of the water extract of dry fruit gained after gac, acetone treatment has the effect of anti-Chinese mugwort sarcoma. 3, from immature fruit, the milk of gained can suppress rat implantation sarcoma, mouse spontaneous mammary carcinoma, causes neoplasm necrosis; The development of transplantability gland cancer, myelomatosis, lymphosarcoma can be delayed again so that it is degenerate. Nature and flavor: sweet; Cool in nature. Gui Jing: lung; Stomach; Large intestine channel. Function cures mainly: clearing heat and promoting fluid; Spleen benefiting and stimulating the appetite; Detoxify and promote the subsdence of swelling. Main swelling and pain in the throat; Cough caused by dryness trachyphonia; Milk is rare; The hot constipation of intestines; Poor appetite; Maldigestion, dysentery; Carbuncle swells; Tinea disease.

Rhizome of Japanese Butterbur: base is former: for feverfew Rhizome of Japanese Butterbur rhizome and full grass. Chemical Composition: root is containing Rhizome of Japanese Butterbur element 50～55%; also containing carene-3, refined sill orchid tree oil alkene, α-santal terpenes, thymol first ether, furans refined sill orchid tree oil alkane, Farfugium kaemferi ketenes, white Rhizome of Japanese Butterbur element and its angelate, 6-hydroxyeremophilenolide, white Rhizome of Japanese Butterbur element first ether, furans Rhizome of Japanese Butterbur alcohol, 6-acetyl furan Rhizome of Japanese Butterbur alcohol, 6-angeloyl groups furans Rhizome of Japanese Butterbur alcohol, sulphur-furans Rhizome of Japanese Butterbur diester, furans Rhizome of Japanese Butterbur monoesters, and choline, Protocatechuic Acid, angelicic acid, caproic acid, sad, β-sitosterol, flavonoid compound etc. Nature and flavor: " Jiangxi herbal medicine ": " toil, cool. " function cures mainly: 1. " Jiangxi herbal medicine ": " detoxification and removing stasis. Treating tonsillitis, carbuncle swells serious case of furuncle, venomous snake bite. " 2. " Zhejiang conventional herbal medicine among the people ": " swelling and pain relieving, detoxification and removing stasis. Control wound, venomous snake bite. "

Flower of Chu-lan Tree flower: base is former: be the flower of Meliaceae plant Flower of Chu-lan Tree. Chemical Composition: flower is containing volatile oil, and the main component in volatile oil has: a-oxalene, the a-flaw in a piece of jade (king's bar) alkene, β-cloves alkene, β-cubebene, β-gurjunene and cubebene etc. Nature and flavor: pungent; Sweet; Flat. Function cures mainly: promoting the circulation of QI to alleviate the stagnation in middle-JIAO; A surname's lung cough-relieving. Main chest diaphragm is full vexed; Dysphagic from the beginning of; Cold cough.

Philippine Violet Herb: base is former: this product is the dry full grass of Violaceae Chinese violet. Nature and flavor: bitter, pungent, cold. Gui Jing: the thoughts of returning home, Liver Channel. Function with cure mainly: clearing heat and detoxicating, cool blood subside a swelling. For furuncle swelling toxin, ulcer carbuncle on the back, erysipelas, venomous snake bite.

Seed of Arillus Longan: base is former: be the seed of sapindaceous plant longan. Chemical Composition: core is containing saponaretin and fat. Chemical Composition: seed is containing three seed amino acids: 2-amino-4-methyl-5-is alkynes acid, 2-amino-4-methylol-5-hexynoic acid and 2-amino-4-hydroxy-6-heptynoic acid.Containing two hydrogen sterculic acids in seed oil. Nature and flavor: bitter; Puckery; Flat. Gui Jing: liver; Spleen; Bladder warp. Function cures mainly: promoting QI to circulate and dispersing the agglomeration of the pathogens; Hemostasis; Eliminating dampness. Main hernia; Scrofula; Wound hemorrhage; Underarm odor; Mange; Wet sore.

Auspicious even grass: base is former: for feverfew bores the full grass of leaf aster. Chemical Composition: full grass is containing apigenin-7-O-beta-D glycoside, apigenin-7-O-beta-D-galactoside, Kaempferol-O-β-D glycoside 3-O-β-D-galactoside-O-α-L-rhamanopyranosyl trifolitin, Quercetin-3-O-β-D-glucopyranoside and apigenin, trifolitin, luteolin, Quercetin and chlorogenic acid. Nature and flavor: bitter; Acid; Cool in nature. Function cures mainly: clearing heat and detoxicating. Main carbuncle swells; Eczema.

Semipinnated Brake Herb: base is former: be Pteridaceae Herba Pteridis creticae platymiscium Semipinnated Brake Herb, with all herbal medicine. Nature and flavor: bitter, pungent, cool. Function cures mainly: clearing heat and detoxicating, swelling and pain relieving. For bacillary dysentery, acute enteritis, icterohepatitis, conjunctivitis; Wound is controlled in external application, traumatic hemorrhage, and sore furuncle swells, eczema, venomous snake bite.

Semen Celosiae: base is former: be the seed of amaranthaceous plant feather cockscomb. Chemical Composition: the fatty oil of Semen Celosiae about 15%, starch 30.8%, nicotinic acid about 14 μ g/g and abundant saltpetre. Contained fatty oil is called Semen Celosiae grease. Pharmacological action: 1. anti-microbial effect savors decoction relatively high inhibition effect to Pseudomonas aeruginosa, and infected wound is through using 10% decoction, and Pseudomonas aeruginosa not regrowth, to wound without obvious stimulation. 2. dry powder can shorten the plasma in rabbit calcification time again. 3. having reducing iop Semen Celosiae water decocting liquid (every 1ml is equivalent to 1g crude drug) to be had no significant effect by normal rabbits pupil, continuous use is after 6 days, and intraocular pressure has slight decline, and control group comparing difference shows, but the intraocular pressure after Water l oad can not be stoped to raise. Nature and flavor: bitter; Cold in nature. Gui Jing: Liver Channel. Function cures mainly: heart heat of dispelling; Clearing away the liver-fire; Improving acuity of vision and removing nebula. Main conjunctival congestion with pain and swelling of the eye; Screen of looking unfamiliar film; Blurring of vision; Essential hypertension; Nosebleed epistaxis; Skin wind-heat itch; Sore tinea.

Moellendorfs Spidemoss Herb: base is former: be the full grass of Spikemoss plant Herba Selaginellae Involventis. Chemical Composition: containing different fennel coumarin, β-sitosterol, palmitinic acid, stearic acid. Pharmacological action: 1, anastalsis: extract (may for aldehyde constituents) in vitro and whole animal all have and accelerate that blood is solidifying and anastalsis, the dissolving of scleroproein can be postponed, total number of blood platelet in rabbit tip blood can be increased, leukocyte count also has rising. Nature and flavor: sweet; Pungent; Flat; Nontoxic. Gui Jing: liver; Courage; Lung channel. Function cures mainly: clearing heat and promoting diuresis; Hemostasis. Main lung heat is spat blood; Spit blood; Bleeding from five sense organs or subcutaneous tissue; Have blood in stool; Bleeding hemorrhoids; Traumatic hemorrhage; Heating; Infantile convulsion; Jaundice due to damp-heat; Gonorrhoea; Oedema; Burn due to hot liquid or fire.

A kind of traditional Chinese medicine for outer use curing underarm odor provided by the invention, scientific formula, preparation method is simple, and products obtained therefrom is convenient for carrying, soon effective, curative ratio height. In addition, the excellent results of the present invention also shows:

1, the present invention uses theory of traditional Chinese medical science to analyze prescription composition, and according to each physico-chemical property of flavour of a drug ingredient and the result of study of pharmacological action, research obtains rationally, the preparation method of effective activeconstituents;

2, gained medicine of the present invention is except the antiperspirant deodorant on surface, additionally it is possible to dredging the meridian, and removing summer-heat endogenous toxic material is damp and hot, extracts the root of underarm odor, thus reaches the object treated both principal and secondary aspect of disease;

3, medicine medicine source of the present invention is easy to get, and medicinal material is with low cost, it is possible to alleviate patient body and psychological burden; And without any side effects or untoward reaction, safe and effective, be suitable for applying.

Embodiment

The technical scheme of the present invention is described in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.

Embodiment 1 one kinds of traditional Chinese medicine for outer use curing underarm odor, are prepared from by following bulk drugs, are weight part (300g/ part): Herba Lophatheri 8 parts; JapaneseFloweringFernRhizome 5 parts; Herba Diclipterae Chinensis 7 parts; Chinese yam 6 parts; Fructus Fici 4 parts; Rhizome of Japanese Butterbur 8 parts; Flower of Chu-lan Tree spends 6 parts; Philippine Violet Herb 9 parts; Seed of Arillus Longan 5 parts; Auspicious even grass 7 parts; Semipinnated Brake Herb 4 parts; Semen Celosiae 3 parts; Moellendorfs Spidemoss Herb 6 parts.

The preparation method of the spray agent of a kind of traditional Chinese medicine for outer use curing underarm odor is:

(2) Semen Celosiae and Philippine Violet Herb mixing, the ginger juice adding 0.85 times amount is mixed thoroughly, vexed 24 minutes, is then placed in steamer, and supreme vapour is steamed in big fire, takes out, smashes juice, and juice filters, for subsequent use;

(3) seed of Arillus Longan and Moellendorfs Spidemoss Herb, Semipinnated Brake Herb, Herba Lophatheri and JapaneseFloweringFernRhizome after step (1) being concocted together grind powder, the alcohol steep adding 60% 1 day, collect vat liquor, filter, and filtrate is for subsequent use;

(4) by Herba Diclipterae Chinensis, Chinese yam, Fructus Fici, Rhizome of Japanese Butterbur, Flower of Chu-lan Tree flower and auspicious even grass mixing, it is placed in medicine pot, adding clear water and do not have powder 3-5cm, slow fire boiling twice, first time decocts and boils 36 minutes, second time is decocted and is boiled 18 minutes, merging twice decocting liquid, filter, filtrate merges with step (2) and (3) gained filtrate, obtain mixing solutions, for subsequent use;

(5) step (4) gained mixing solutions is evaporated to the 1/3 of original volume, through millipore filtration membrane filtration, add other auxiliary material (auxiliary material to be massfraction be 0.73% borneol and massfraction be the primary ammonium phosphate of 0.35%), mixed even, bottling, to obtain final product.

The using method of gained of the present invention spray agent is: cleaned at armpit position clean, and under drying rear direct evenly spraying 2-3, every day respectively once, 20 days is a course for the treatment of sooner or later.

Embodiment 2 one kinds of traditional Chinese medicine for outer use curing underarm odor, are prepared from by following bulk drugs, are weight part (140g/ part): Herba Lophatheri 13 parts; JapaneseFloweringFernRhizome 11 parts; Herba Diclipterae Chinensis 12 parts; Chinese yam 11 parts; Fructus Fici 8 parts; Rhizome of Japanese Butterbur 12 parts; Flower of Chu-lan Tree spends 13 parts; Philippine Violet Herb 12 parts; Seed of Arillus Longan 12 parts; Auspicious even grass 13 parts; Semipinnated Brake Herb 9 parts; Semen Celosiae 7 parts; Moellendorfs Spidemoss Herb 10 parts.

The preparation method of the ointment of a kind of traditional Chinese medicine for outer use curing underarm odor is:

(1) it is placed in round-bottomed flask by broken for Flower of Chu-lan Tree pollen, adds the distilled water immersion 3.5 hours of 20 times amount, then extract volatile oil according to vapor extraction method, for subsequent use;

(2) surplus stock medicine is fully dry, smash into meal to pieces, load in penetrating bag, the distilled water slow fire boiling twice of the times amount that adds 10, each each decocting boils 47 minutes, merges twice decocting liquid, filtering, filtrate concentrates to liquid than being 1:1.7, and adding ethanol makes alcohol content be 50%, leave standstill 9 hours, filter, reclaim ethanol, concentrating under reduced pressure becomes medicinal extract, adds step (1) gained volatile oil, mixed even, sealing, obtains Chinese medical concrete, for subsequent use;

(3) distilled water of the Vaseline of 2.3 times of Chinese medical concrete amounts, the sodium lauryl sulphate of 0.2 times of Chinese medical concrete amount and 8 times of Chinese medical concrete amounts is got, mixing, 75 DEG C of stirring in water bath fusings, obtained creamy base, for subsequent use;

The using method of gained ointment of the present invention is: is cleaned at armpit position after totally drying, gets appropriate ointment of the present invention and be evenly applied in affected part, every day 3 times, within 20 days, be a course for the treatment of.

Model case: Zhao XX, female, 19 years old, teacher. Patient's readme: because familial inheritance reason, from middle school, there is a strand smell for thorn honey at conscious armpit place, highly seasoned, to such an extent as to deskmate and front and back table classmate can smell, and oneself becoming slowly is felt oneself inferior very much, is afraid of by others' words. Winter, situation was slightly good, but summer is the most hard to bear, and the strong peculiar smell in armpit place always allows people shy away. The head of a family once band patient treat to multiple examination in hospital, used various external application to add pharmacological agent for oral administration, effect is difficult to satisfactory. Made some inquiries about through the head of a family afterwards, carried out here treatment on May 9th, 2013. Agree to through patient and the head of a family, it may also be useful to the ointment of a kind of traditional Chinese medicine for outer use curing underarm odor of the present embodiment gained, it may also be useful to method: armpit position is cleaned after totally drying, get appropriate ointment of the present invention and be evenly applied in affected part, every day 3 times, within 20 days, be a course for the treatment of. After treating two courses for the treatment of, obviously reducing before the conscious perspire of patient relatively, smell significantly alleviates, and use the present invention stopped using after four courses for the treatment of continuously, and private prosecution perspire amount is normal, and body odour is normal, follows up a case by regular visits to half a year, nothing recurrence.

Embodiment 3 one kinds of traditional Chinese medicine for outer use curing underarm odor, are prepared from by following bulk drugs, are weight part (260g/ part): Herba Lophatheri 9.5 parts; JapaneseFloweringFernRhizome 7 parts; Herba Diclipterae Chinensis 8.5 parts; Chinese yam 7.5 parts; Fructus Fici 5 parts; Rhizome of Japanese Butterbur 9 parts; Flower of Chu-lan Tree spends 8 parts; Philippine Violet Herb 10 parts; Seed of Arillus Longan 7 parts; Auspicious even grass 9 parts; Semipinnated Brake Herb 5 parts; Semen Celosiae 4 parts; Moellendorfs Spidemoss Herb 7 parts.

The preparation method of the pulvis of a kind of traditional Chinese medicine for outer use curing underarm odor is:

(2) Chinese yam cuts thin slice, adds light-coloured vinegar and soaks 3.5 hours, takes out, together it is placed in thermostatic drying chamber with Rhizome of Japanese Butterbur, Herba Diclipterae Chinensis and Semipinnated Brake Herb, in 84 DEG C of dryings 28 minutes, then adjusts the temperature to 60 DEG C of dryings 3 hours, take out, together it is ground into fine powder with the seed of Arillus Longan after step (1) processes, for subsequent use;

(3) surplus stock medicine is placed in frying pan, boiling twice, the clear water of times amount that first time adds 13.5, slow fire boiling 50 minutes, the clear water of times amount that second time adds 7.5, slow fire boiling 38 minutes, merges twice decocting liquid, filters, filtrate decompression concentrate to 80 DEG C of relative densities be the thick cream of 1.30-1.33, spraying dry, get dry extract powder, for subsequent use;

(4) step (2) gained fine powder and step (3) gained dried cream powder being mixed, cross 65 order sieves, sterile packaged, to obtain final product.

The using method of gained pulvis of the present invention is: is cleaned at armpit position after totally drying, gets appropriate pulvis of the present invention and smear 3-4 time every day, within 20 days, be a course for the treatment of.

Embodiment 4 one kinds of traditional Chinese medicine for outer use curing underarm odor, are prepared from by following bulk drugs, are weight part (180g/ part): Herba Lophatheri 11.5 parts; JapaneseFloweringFernRhizome 9 parts; Herba Diclipterae Chinensis 10.5 parts; Chinese yam 9.5 parts; Fructus Fici 7 parts; Rhizome of Japanese Butterbur 11 parts; Flower of Chu-lan Tree spends 11 parts; Philippine Violet Herb 11 parts; Seed of Arillus Longan 10 parts; Auspicious even grass 11 parts; Semipinnated Brake Herb 8 parts; Semen Celosiae 6 parts; Moellendorfs Spidemoss Herb 9 parts.

The preparation method of the vina of a kind of traditional Chinese medicine for outer use curing underarm odor is:

(2) it is placed in round-bottomed flask by broken for Flower of Chu-lan Tree pollen, adds the distilled water immersion 3.5 hours of 20 times amount, then according to extraction by steam distillation volatile oil, for subsequent use;

(3) surplus stock medicine is fully dry, seed of Arillus Longan after processing with step (1) together pulverizes into fine powder, loads in the penetrating bag of Chinese medicine, adds white wine, sealing is soaked 7 days, jolting twice every day period, filters, and filtrate decompression concentrates to medicinal liquor than being 1:3, add step (2) gained volatile oil, mixed even, sterilizing encapsulates, and to obtain final product.

The using method of gained vina of the present invention is: cleaned at armpit position after totally drying, and gets this vina in right amount and puts on the skin 3-4 time outside every day, and 20 days is a course for the treatment of.

Model case a: XX, man, 21 years old, student. Patient is a dance academy student, is good at Latin dancing, modern dance and national dance, is excellent student of good character and fine scholarship in institute. It is many that patient played conscious pair of side armpit perspire amount in 2010, has obvious peculiar smell, and rear peculiar smell of every time rehearse increases the weight of, dare not be adjacent with dancing partner and sit when causing rest, and also total worry peculiar smell with it can make dancing partner away from oneself. After the head of a family learns, band patient goes to certain examination in hospital local, is diagnosed as underarm odor. Successively attempt using various pharmacological agent, but mostly can only temporarily alleviate, can not thoroughly effect a radical cure. Pharmacological agent underarm odor of the present invention was evident in efficacy upon somebody's introduction afterwards, curative ratio height, then carried out my institute's treatment on October 9th, 2011. Using the vina of a kind of traditional Chinese medicine for outer use curing underarm odor of the present embodiment gained, it may also be useful to method: cleaned at armpit position after totally drying, get this vina in right amount and put on the skin 3-4 time outside every day, 20 days is a course for the treatment of. After treating two courses for the treatment of, obviously reducing before the conscious perspire of patient relatively, smell significantly alleviates, and use the present invention stopped using after four courses for the treatment of continuously, and private prosecution perspire amount is normal, and body odour is normal, follows up a case by regular visits to half a year, nothing recurrence.

Embodiment 5 one kinds of traditional Chinese medicine for outer use curing underarm odor, are prepared from by following bulk drugs, are weight part (220g/ part): Herba Lophatheri 10.5 parts; JapaneseFloweringFernRhizome 8 parts; Herba Diclipterae Chinensis 9.5 parts; Chinese yam 8.5 parts; Fructus Fici 6 parts; Rhizome of Japanese Butterbur 10 parts; Flower of Chu-lan Tree spends 9.5 parts; Philippine Violet Herb 10.5 parts; Seed of Arillus Longan 8.5 parts; Auspicious even grass 10 parts; Semipinnated Brake Herb 6.5 parts; Semen Celosiae 5 parts; Moellendorfs Spidemoss Herb 8 parts.

(2) Semen Celosiae and Philippine Violet Herb mixing, the ginger juice adding 1.1 times amount is mixed thoroughly, vexed 32 minutes, is then placed in steamer, and supreme vapour is steamed in big fire, takes out, smashes juice, and juice filters, for subsequent use;

(3) seed of Arillus Longan and Moellendorfs Spidemoss Herb, Semipinnated Brake Herb, Herba Lophatheri and JapaneseFloweringFernRhizome after step (1) being concocted together grind powder, the alcohol steep adding 60% 2 days, collect vat liquor, filter, and filtrate is for subsequent use;

(4) by Herba Diclipterae Chinensis, Chinese yam, Fructus Fici, Rhizome of Japanese Butterbur, Flower of Chu-lan Tree flower and auspicious even grass mixing, it is placed in medicine pot, adding clear water and do not have powder 3-5cm, slow fire boiling twice, first time decocts and boils 43 minutes, second time is decocted and is boiled 24 minutes, merging twice decocting liquid, filter, filtrate merges with step (2) and (3) gained filtrate, obtain mixing solutions, for subsequent use;

The clinical application of a kind of traditional Chinese medicine for outer use (embodiment 5) curing underarm odor of test example 1 gained of the present invention:

1, physical data

Choose 336 example underarm odor patients of my institute treatment in September ,-2014 in July, 2010, the wherein male sex 185 example, women 151 example, the age 17-33 year. All patients are divided into experimental group and control group at random, and two groups of patient's comparing difference not statistically significants (P > 0.05) in age, sex, the state of an illness etc., have comparability.

2, Case definition

(1) there is fox urine stink, movable heating postemphasis; (2) armpit hair has yellow-white fine crystalline particle or with the liquid adhesion thing more sticky than sweat; (3) observing ear Ding (cerumen) is sugar ear, the oil similar otitis media of ear, the wet sticky property ear Ding of property; (4) underwear armpit position is worn in observation jaundice metachromatism.

3, methods for the treatment of

Experimental group uses a kind of traditional Chinese medicine for outer use curing underarm odor of gained of the present invention, it may also be useful to method: cleaned at armpit position clean, and under drying rear directly even spraying 2-3, every day respectively once, 20 days is a course for the treatment of sooner or later. Control group uses other medicine (such as bromhidrosis powder, XISHILANXIALU spray, half month conventional medicine such as clear). Treat four courses for the treatment of altogether.

4, efficacy assessment standard

Cure: underarm odor symptom and sign completely dissolve after treatment, stop medicine after three months without recurrence;

Effective: after treatment, armpit only can smell less malodor;

Invalid: after treatment, underarm odor symptom is relatively treated front unchanged.

Always there is efficiency=(curing number of cases+effective number of cases)/total observation case number × 100%.

5, result for the treatment of

Result is as shown in table 1.

Table 1: the treatment result of experimental group and control group underarm odor patient

Result for the treatment of: experimental group cures 149 examples (79.3%), effective 39 examples (20.7%), invalid 0 example, always has efficiency to be 100%. And control group always has efficiency to be 84.5%. By table 1 data it will be seen that experimental group result for the treatment of is obviously better than control group.

The present invention select Herba Lophatheri, JapaneseFloweringFernRhizome, Herba Diclipterae Chinensis, Chinese yam, Fructus Fici, Rhizome of Japanese Butterbur and Flower of Chu-lan Tree flower etc. totally 13 taste main raw materials be prepared from. Fang Zhong, Herba Lophatheri clearing away the heart-fire, except dysphoria with smothery sensation; JapaneseFloweringFernRhizome is clearing heat and detoxicating, antibacterial kills worm; Herba Diclipterae Chinensis heat-clearing, profit is wet, removing toxic substances; Fructus Fici clearing heat and promoting fluid, detoxify and promote the subsdence of swelling; Flower of Chu-lan Tree flower promoting the circulation of QI to alleviate the stagnation in middle-JIAO; Seed of Arillus Longan promoting the circulation of QI to remove dampness; Semen Celosiae is dispelled heart heat, clearing away the liver-fire. All medicines share, and dredging key network, removing summer-heat endogenous toxic material is damp and hot, extracts the root of underarm odor, thus reaches the object treated both principal and secondary aspect of disease. Treating four courses for the treatment of in experimental group, always have efficiency to be 100%, curative effect is definite, and safety has no side effect.

It should be appreciated that the embodiment more representational example that is the present invention, it is clear that the technical scheme of the present invention is not limited to above-described embodiment, it is also possible to have a lot of distortion. The those of ordinary skill of this area, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims

1. cure the traditional Chinese medicine for outer use of underarm odor for one kind, it is characterised in that, it is prepared from by following bulk drugs, it is weight part: Herba Lophatheri 8-13; JapaneseFloweringFernRhizome 5-11; Herba Diclipterae Chinensis 7-12; Chinese yam 6-11; Fructus Fici 4-8; Rhizome of Japanese Butterbur 8-12; Flower of Chu-lan Tree flower 6-13;Philippine Violet Herb 9-12; Seed of Arillus Longan 5-12; Auspicious even grass 7-13; Semipinnated Brake Herb 4-9; Semen Celosiae 3-7; Moellendorfs Spidemoss Herb 6-10.

2. a kind of traditional Chinese medicine for outer use curing underarm odor as claimed in claim 1, it is characterised in that, it is prepared from by following bulk drugs, it is weight part: Herba Lophatheri 9.5-11.5; JapaneseFloweringFernRhizome 7-9; Herba Diclipterae Chinensis 8.5-10.5; Chinese yam 7.5-9.5; Fructus Fici 5-7; Rhizome of Japanese Butterbur 9-11; Flower of Chu-lan Tree flower 8-11; Philippine Violet Herb 10-11; Seed of Arillus Longan 7-10; Auspicious even grass 9-11; Semipinnated Brake Herb 5-8; Semen Celosiae 4-6; Moellendorfs Spidemoss Herb 7-9.

3. a kind of traditional Chinese medicine for outer use curing underarm odor as claimed in claim 1, it is characterised in that, it is prepared from by following bulk drugs, it is weight part: Herba Lophatheri 10.5; JapaneseFloweringFernRhizome 8; Herba Diclipterae Chinensis 9.5; Chinese yam 8.5; Fructus Fici 6; Rhizome of Japanese Butterbur 10; Flower of Chu-lan Tree spends 9.5; Philippine Violet Herb 10.5; Seed of Arillus Longan 8.5; Auspicious even grass 10; Semipinnated Brake Herb 6.5; Semen Celosiae 5; Moellendorfs Spidemoss Herb 8.

4. the preparation method of the spray agent of a kind of traditional Chinese medicine for outer use curing underarm odor as described in as arbitrary in claim 1-3, it is characterised in that, step is as follows:

5. the preparation method of the spray agent of a kind of traditional Chinese medicine for outer use curing underarm odor according to claim 4, it is characterised in that, auxiliary material described in step (5) to be massfraction be 0.73% borneol and massfraction be the primary ammonium phosphate of 0.35%.

6. the preparation method of the ointment of a kind of traditional Chinese medicine for outer use curing underarm odor as described in as arbitrary in claim 1-3, it is characterised in that, step is as follows:

7. the preparation method of the ointment of a kind of traditional Chinese medicine for outer use curing underarm odor according to claim 6, it is characterized in that, the temperature of step (3) water-bath is 65-85 DEG C (temperature of preferred water-bath is 70-80 DEG C, and the temperature of water-bath more preferably is 75 DEG C).

8. the preparation method of the pulvis of a kind of traditional Chinese medicine for outer use curing underarm odor as described in as arbitrary in claim 1-3, it is characterised in that, step is as follows:

9. the preparation method of the pulvis of a kind of traditional Chinese medicine for outer use curing underarm odor according to claim 8, it is characterised in that, step (4) is crossed 45-85 order sieve (preferred 55-75 order of crossing sieves, mistake 65 order sieve more preferably).

10. the preparation method of the vina of a kind of traditional Chinese medicine for outer use curing underarm odor as described in as arbitrary in claim 1-3, it is characterised in that, step is as follows: