CN105343271A

CN105343271A - Medicine for treating beriberi and preparation method of medicine

Info

Publication number: CN105343271A
Application number: CN201510878237.4A
Authority: CN
Inventors: 彭连志
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-12-04
Filing date: 2015-12-04
Publication date: 2016-02-24

Abstract

The invention discloses a medicine for treating beriberi and a preparation method of the medicine. The medicine is mainly prepared from the following components according to a certain weight ratio: lilac, phellodendron amurense, gallnut, kudzuvine root, spina gleditsiae, xanthoxyli fructus, densefruit pittany root-bark and white vaseline. The medicine has functions of dispelling wind-evil to draw out poison, removing swelling for apocenosis, and clearing heat to dry dampness, is used for treating beriberi, and is high in treating efficiency and good in treating effect.

Description

A kind of medicine for the treatment of beriberi and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of beriberi and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Beriberi, is also tinea pedis, tinea pedis, is a kind of extremely common fungal infection dermatoses.Have the people of 70-80% to suffer from beriberi in adult, just weight is different.Beriberi is everlasting and is increased the weight of summer, and winter alleviates, and also has people not heal all the year round.Because current Western medicine effectively cannot treat beriberi, therefore there is great demand in the Chinese medicine of people to rapid, effective treatment beriberi, up to now, also do not find about relevant report of the present invention.

Summary of the invention

The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment beriberi, thus completes the present invention.

Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment beriberi.

Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.

Medicine of the present invention selects Flos Caryophylli, Cortex Phellodendri, Galla Chinensis, Radix Puerariae, Spina Gleditsiae, Pericarpium Zanthoxyli, Cortex Dictamni, white vaseline to combine, and is made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat beriberi.Wherein select Flos Caryophylli to be because its nature and flavor are pungent, temperature, enter stomach, spleen, kidney channel, have warming middle-JIAO, warming the kidney, the function of sending down the abnormal ascending QI, controls singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, tinea disease.Cortex Phellodendri is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Galla Chinensis is selected to be because its nature and flavor acid, flat.Enter lung, stomach, large intestine channel.Astringe the lung, astringing intestine to stop diarrhea, hemostasis, removing toxic substances.Control chronic cough of deficiency lung, chronic dysentery, chronic diarrhea, proctoptosis, spontaneous perspiration, night sweat, seminal emission, has blood in stool, epistaxis, metrorrhagia, traumatic hemorrhage, toxic swelling, furuncle, trichiasis.Select Radix Puerariae to be because its nature and flavor are sweet pungent, flat, enter spleen, stomach warp, have yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, the function that relieving restlessness is quenched the thirst, cure the wound cold, warm, headache, stiffness of the nape, dysphoria with smothery sensation disappears and drinks, and has loose bowels, dysentery, and abnormal pigmentary deposit on the skin is examined not saturating, hypertension, and angina pectoris is deaf.Select Spina Gleditsiae to be that temperature, searches wind, draw out pus by applying a plaster to the affected part because its nature and flavor are pungent, detumescence, the function of evacuation of pus, controls carbuncle, sore, leprosy, tinea skin ulcer, placenta retention.Pericarpium Zanthoxyli is selected to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, lung, kidney channel, have warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, parasite killing, separate fish raw meat poison, control food stagnation and stop drink, trusted subordinate's cold type of pain, vomiting, oh, cough with dyspnea, anemofrigid-damp arthralgia, has loose bowels, dysentery, colic, toothache, ascariasis, enterobiasis, pudendal pruritus, skin ulcer scabies.Cortex Dictamni is selected to be because its nature and flavor are bitter, salty, cold, enter spleen, stomach warp, dispel the wind, dampness, heat clearing away, the function of removing toxic substances, control wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice.Select white vaseline to be because it has water proofing property, be a kind of moisturizing articles for use, be usually used in preparing medical ointment and skin care ointment.

Detailed description of the invention

The drug dose of the present invention's combination is also that inventor draws through groping in a large number to sum up, and the consumption of each grouping all has good therapeutic effect within the scope of following weight:

Flos Caryophylli 5-15g, Cortex Phellodendri 4-12g, Galla Chinensis 4-12g, Radix Puerariae 5-15g,

Fructus Gleditsia 10-20g, Pericarpium Zanthoxyli 10-20g, Cortex Dictamni 10-20g, white vaseline 150-250g

Be preferably:

Flos Caryophylli 10g, Cortex Phellodendri 8g, Galla Chinensis 7g, Radix Puerariae 12g,

Fructus Gleditsia 16g, Pericarpium Zanthoxyli 18g, Cortex Dictamni 15g, white vaseline 200g

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Flos Caryophylli: look for decontamination, bennet, sieve dedust bits, the used time smashs to pieces;

2, Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;

3, Galla Chinensis: pick clean, knock open, remove wherein impurity;

4, Radix Puerariae: pick decontamination, cleans, is soaked in water, pulls out, run through, cut into slices in time, dry;

5, Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries;

6, Pericarpium Zanthoxyli: removing fruit stem and seed (Semen zanthoxyli), to put in pot stir-fry to making sound, oil goes out, take out, cool;

7, Cortex Dictamni: pick clean impurity, removing rough bark, cleans, slightly moistens, and section, dries;

8, white vaseline: the white vaseline getting described weight, for subsequent use.

Two, prepare

1, described Flos Caryophylli, Cortex Phellodendri, Galla Chinensis, Radix Puerariae, Spina Gleditsiae, Pericarpium Zanthoxyli, Cortex Dictamni are cleaned up and are placed in open air and dry.

2, the above-mentioned medical material dried is ground into fine powder.

3, the medicamental pulverata being ground into fine powder added white vaseline and mix thoroughly, the ointment of beriberi must be treated.

Medicine of the present invention has to be searched wind and draws out pus by applying a plaster to the affected part, and the function of detumescence and apocenosis, heat clearing and damp drying, is used for the treatment of beriberi instant effect, good effect.

Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.

The animal toxicity test of [test example 1] medicine of the present invention

Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, first exposes skin by rabbit abdominal part hair removing, then the ointment configured is spread upon rabbit abdominal part baring skin place, then twine with gauze and tie up, every day coating 2 times, continuous coating 5 days, observe every day administration reaction, result shows that rabbit is movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1, physical data

Accept out-patient's totally 44 examples for medical treatment.

2, diagnostic criteria

Beriberi can be divided into three types usually: erosive type, vesicle, keratinization type, and symptom is:

1) erosive beriberi: be apt to occur between the 3rd and the four, four and five toe.From the beginning of moist between toe, dipping turns white or plays phlysis, and after dry desquamation, peelling off scurf is rotten to the corn face that is moistening, flushing, oddly itches, easy secondary infection.

2) vesicle beriberi: be apt to occur in sufficient edge.From the beginning of being the full phlysis of wall thickness, the be fused into bulla had, bleb liquid is transparent, around without blush.Consciously very to itch, after scratching, often cause erysipelas, lymphangitis etc. because of secondary infection.

3) keratinization type beriberi: be apt to occur in heel.Main manifestations is that skin is slightly thick and dry, keratinization desquamation, scratches where it itches, and easily chaps.This type is without vesicle and suppuration, and the course of disease is slow, does not heal for many years.

3, Therapeutic Method

(1) first disease sites warm water is cleaned up.

(2) the complete affected part of cleaning is toweled off dry.

(3) ointment prepared is coated in affected part, every day, coating 1 time, 7 days was a course for the treatment of, 2 to 3 courses for the treatment of of continuous coating.

4, efficacy assessment standard

Effective: beriberi symptom is controlled, affected part pruritus alleviates, and cutaneous lesion heals gradually, occurs recovering sign.

Take a turn for the better: beriberi disease states improves, and affected part pruritus and erosion no longer aggravate, and the state of an illness progressively takes a turn for the better.

Invalid: not reach improvement standard person.

5, therapeutic outcome (seeing the following form):

In above-mentioned treatment, by Drug therapy beriberi patient 44 example of the present invention, effective 38 examples of result, obvious effective rate is 86.36%, and take a turn for the better 4 examples, and improvement rate is 9.09%, and invalid 2 examples, total effective rate is 4.55%.

Claims

1. treat a medicine for beriberi, it is characterized in that: it is made up of the raw material in following weight range:

Fructus Gleditsia 10-20g, Pericarpium Zanthoxyli 10-20g, Cortex Dictamni 10-20g, white vaseline 150-250g.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Fructus Gleditsia 16g, Pericarpium Zanthoxyli 18g, Cortex Dictamni 15g, white vaseline 200g.

3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:

(1) get the raw materials ready

(1) Flos Caryophylli: look for decontamination, bennet, sieve dedust bits, the used time smashs to pieces;

(2) Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;

(3) Galla Chinensis: pick clean, knock open, remove wherein impurity;

(4) Radix Puerariae: pick decontamination, cleans, is soaked in water, pulls out, run through, cut into slices in time, dry;

(5) Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries;

(6) Pericarpium Zanthoxyli: removing fruit stem and seed (Semen zanthoxyli), to put in pot stir-fry to making sound, oil goes out, take out, cool;

(7) Cortex Dictamni: pick clean impurity, removing rough bark, cleans, slightly moistens, and section, dries;

(8) white vaseline: the white vaseline getting described weight, for subsequent use;

(2) prepare

(1) described Flos Caryophylli, Cortex Phellodendri, Galla Chinensis, Radix Puerariae, Spina Gleditsiae, Pericarpium Zanthoxyli, Cortex Dictamni are cleaned up and are placed in open air and dry;

(2) the above-mentioned medical material dried is ground into fine powder;

(3) medicamental pulverata being ground into fine powder added white vaseline and mix thoroughly, the ointment of beriberi must be treated.