CN105339490A - 乙酰转移酶及其用于产生类胡萝卜素的用途 - Google Patents

乙酰转移酶及其用于产生类胡萝卜素的用途 Download PDF

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Publication number
CN105339490A
CN105339490A CN201380067557.0A CN201380067557A CN105339490A CN 105339490 A CN105339490 A CN 105339490A CN 201380067557 A CN201380067557 A CN 201380067557A CN 105339490 A CN105339490 A CN 105339490A
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seq
seqidno
polypeptide
nucleic acid
zeaxanthin
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Chinese (zh)
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C·法雷尔
P·休斯顿
L·拉普拉德
N·鲍尔奇
M·马约尔加
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DSM IP Assets BV
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DSM IP Assets BV
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01084—Alcohol O-acetyltransferase (2.3.1.84)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CN201380067557.0A 2012-12-20 2013-08-28 乙酰转移酶及其用于产生类胡萝卜素的用途 Pending CN105339490A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12198373.8 2012-12-20
EP12198373 2012-12-20
US201361830234P 2013-06-03 2013-06-03
US61/830,234 2013-06-03
PCT/IB2013/058049 WO2014096992A1 (en) 2012-12-20 2013-08-28 Acetyl transferases and their use for producing carotenoids

Publications (1)

Publication Number Publication Date
CN105339490A true CN105339490A (zh) 2016-02-17

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CN201380067557.0A Pending CN105339490A (zh) 2012-12-20 2013-08-28 乙酰转移酶及其用于产生类胡萝卜素的用途

Country Status (9)

Country Link
US (2) US10465174B2 (enExample)
EP (1) EP2935571B1 (enExample)
JP (2) JP6607567B2 (enExample)
KR (1) KR102205236B1 (enExample)
CN (1) CN105339490A (enExample)
BR (1) BR112015014258B1 (enExample)
CA (1) CA2895166C (enExample)
EA (1) EA033724B1 (enExample)
WO (1) WO2014096992A1 (enExample)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105316246A (zh) * 2014-06-03 2016-02-10 上海来益生物药物研究开发中心有限责任公司 β-胡萝卜素高产菌种及其应用
CN107418938A (zh) * 2016-05-24 2017-12-01 中国医学科学院药物研究所 10-去乙酰巴卡亭III 10β-O-乙酰转移酶突变体及其在催化合成紫杉醇及其类似物中的应用
CN108949599A (zh) * 2018-06-29 2018-12-07 华南理工大学 一种产β-紫罗兰酮基因工程菌及其构建方法与应用
CN109666683A (zh) * 2019-02-27 2019-04-23 昆明理工大学 乙酰辅酶A乙酰转移酶基因RKAcaT2及其应用
CN111107832A (zh) * 2017-09-25 2020-05-05 帝斯曼知识产权资产管理有限公司 视黄酯的生产
CN111107834A (zh) * 2017-09-25 2020-05-05 帝斯曼知识产权资产管理有限公司 类视黄醇的生物合成
CN111454854A (zh) * 2020-05-02 2020-07-28 昆明理工大学 一株产虾青素的红冬孢酵母基因工程菌株
CN115895922A (zh) * 2022-12-19 2023-04-04 云南大学 一株高产类胡萝卜素的禾本红酵母及其应用

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2895166C (en) * 2012-12-20 2022-10-04 Dsm Ip Assets B.V. Acetyl transferases and their use for producing carotenoids
WO2016154314A1 (en) * 2015-03-23 2016-09-29 Arch Innotek, Llc Compositions and methods of biosynthesizing carotenoids and their derivatives
BR112020005757A2 (pt) 2017-09-25 2020-10-13 Dsm Ip Assets B.V. produção de retinol
JP7298812B2 (ja) 2017-09-25 2023-06-27 ディーエスエム アイピー アセッツ ビー．ブイ． レチニルエステルの生産
US20200277644A1 (en) 2017-09-25 2020-09-03 Dsm Ip Assets B.V. Production of trans-retinal
WO2020085879A1 (ko) * 2018-10-26 2020-04-30 경상대학교산학협력단 아세틴 화합물의 생물학적 제조 방법
WO2020141168A1 (en) 2018-12-31 2020-07-09 Dsm Ip Assets B.V. Novel acetyl-transferases
BR112022000683A2 (pt) 2019-07-16 2022-03-03 Dsm Ip Assets Bv Novas betacaroteno oxidases
CN114127259B (zh) 2019-08-01 2024-11-01 帝斯曼知识产权资产管理有限公司 β-胡萝卜素发酵方法
WO2022003130A2 (en) 2020-07-01 2022-01-06 Dsm Ip Assets B.V. Yeast expression system
WO2023006179A1 (en) 2020-07-27 2023-02-02 Dsm Ip Assets B.V. Method to produce retinyl acetate
US20230407344A1 (en) 2020-10-30 2023-12-21 Dsm Ip Assets B.V. Fermentative production of isoprenoids
WO2022090547A1 (en) 2020-10-30 2022-05-05 Dsm Ip Assets B.V. Production of carotenoids by fermentation
US20240018564A1 (en) 2020-10-30 2024-01-18 Dsm Ip Assets B.V. In situ two-phase extraction system
WO2023006851A1 (en) 2021-07-27 2023-02-02 Dsm Ip Assets B.V. Fermentative production of retinyl acetate in the presence of ethanol
EP4419703A1 (en) 2021-10-19 2024-08-28 DSM IP Assets B.V. Retinoid production
KR102414136B1 (ko) * 2021-10-26 2022-06-27 서울대학교산학협력단 제아잔틴을 생산하는 재조합 야로위아 리폴리티카 및 제아잔틴 생산방법
US20250109422A1 (en) 2022-02-02 2025-04-03 Dsm Ip Assets B.V. Yarrowia production process
KR20250140584A (ko) 2023-01-30 2025-09-25 디에스엠 아이피 어셋츠 비.브이. 신규한 아세틸 전이효소
EP4658789A1 (en) 2023-01-30 2025-12-10 DSM IP Assets B.V. Carrp enzyme variants and their use in producing carotenoid and apocarotenoid
WO2024160658A1 (en) 2023-01-30 2024-08-08 Dsm Ip Assets B.V. Novel mutants of acetyl-transferase sb-atf

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1630718A (zh) * 2001-06-06 2005-06-22 Dsmip资产公司 改进的类异戊二烯生产
WO2009037329A3 (en) * 2007-09-21 2009-05-28 Basf Plant Science Gmbh Plants with increased yield

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3363197B2 (ja) * 1992-06-18 2003-01-08 麒麟麦酒株式会社 アルコールアセチルトランスフェラーゼ遺伝子およびその利用
JP3363198B2 (ja) * 1993-02-26 2003-01-08 麒麟麦酒株式会社 エステル香味の低減した酒類の製造
DE19801120A1 (de) 1998-01-15 1999-07-22 Basf Ag Orotidin-5'-Phosphatdecarboxylase-Gen, Genkonstrukt enthaltend dieses Gen und seine Verwendung
JP5074185B2 (ja) 2004-08-19 2012-11-14 ディーエスエム アイピー アセッツ ビー．ブイ． イソプレノイドの生成
CN103589650A (zh) * 2005-03-18 2014-02-19 米克罗比亚公司 产油酵母和真菌中类胡萝卜素的产生
WO2009006386A2 (en) * 2007-06-29 2009-01-08 The Regents Of The University Of California Host cells and methods for producing isoprenyl alkanoates
US20100297722A1 (en) * 2009-05-20 2010-11-25 Board Of Trustees Of Southern Illinois University Transgenic moss producing terpenoids
CA2895166C (en) 2012-12-20 2022-10-04 Dsm Ip Assets B.V. Acetyl transferases and their use for producing carotenoids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1630718A (zh) * 2001-06-06 2005-06-22 Dsmip资产公司 改进的类异戊二烯生产
WO2009037329A3 (en) * 2007-09-21 2009-05-28 Basf Plant Science Gmbh Plants with increased yield

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BOMEMAN,A.R.等: "EGA72844.1", 《UNIPROT》 *

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105316246A (zh) * 2014-06-03 2016-02-10 上海来益生物药物研究开发中心有限责任公司 β-胡萝卜素高产菌种及其应用
CN105316246B (zh) * 2014-06-03 2019-10-01 上海来益生物药物研究开发中心有限责任公司 β-胡萝卜素高产菌种及其应用
CN107418938B (zh) * 2016-05-24 2022-07-15 中国医学科学院药物研究所 10-去乙酰巴卡亭III 10β-O-乙酰转移酶突变体及其在催化合成紫杉醇及其类似物中的应用
CN107418938A (zh) * 2016-05-24 2017-12-01 中国医学科学院药物研究所 10-去乙酰巴卡亭III 10β-O-乙酰转移酶突变体及其在催化合成紫杉醇及其类似物中的应用
CN111107832A (zh) * 2017-09-25 2020-05-05 帝斯曼知识产权资产管理有限公司 视黄酯的生产
CN111107834A (zh) * 2017-09-25 2020-05-05 帝斯曼知识产权资产管理有限公司 类视黄醇的生物合成
US12252724B2 (en) 2017-09-25 2025-03-18 Dsm Ip Assets B.V. Biosynthesis of retinoids
US11578344B2 (en) 2017-09-25 2023-02-14 Dsm Ip Assets B.V. Biosynthesis of retinoids
CN108949599A (zh) * 2018-06-29 2018-12-07 华南理工大学 一种产β-紫罗兰酮基因工程菌及其构建方法与应用
CN109666683A (zh) * 2019-02-27 2019-04-23 昆明理工大学 乙酰辅酶A乙酰转移酶基因RKAcaT2及其应用
CN109666683B (zh) * 2019-02-27 2021-10-29 昆明理工大学 乙酰辅酶A乙酰转移酶基因RKAcaT2及其应用
CN111454854B (zh) * 2020-05-02 2022-05-06 昆明理工大学 一株产虾青素的红冬孢酵母基因工程菌株
CN111454854A (zh) * 2020-05-02 2020-07-28 昆明理工大学 一株产虾青素的红冬孢酵母基因工程菌株
CN115895922A (zh) * 2022-12-19 2023-04-04 云南大学 一株高产类胡萝卜素的禾本红酵母及其应用
CN115895922B (zh) * 2022-12-19 2024-04-02 云南大学 一株高产类胡萝卜素的禾本红酵母及其应用

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JP2018183139A (ja) 2018-11-22
EA033724B1 (ru) 2019-11-20
US10465174B2 (en) 2019-11-05
US20150322412A1 (en) 2015-11-12
CA2895166C (en) 2022-10-04
WO2014096992A1 (en) 2014-06-26
BR112015014258B1 (pt) 2022-05-17
US10865392B2 (en) 2020-12-15
JP6607567B2 (ja) 2019-11-20
CA2895166A1 (en) 2014-06-26
WO2014096992A8 (en) 2015-12-23
EP2935571B1 (en) 2018-03-07
EP2935571A1 (en) 2015-10-28
KR102205236B1 (ko) 2021-01-20
KR20150096754A (ko) 2015-08-25
JP2016501543A (ja) 2016-01-21
EA201500659A1 (ru) 2015-12-30
US20200123507A1 (en) 2020-04-23
BR112015014258A2 (enExample) 2017-08-22

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Application publication date: 20160217