CN105327197A - Traditional Chinese medicine for treating damp-heat internal invasion type viral myocarditis in children - Google Patents
Traditional Chinese medicine for treating damp-heat internal invasion type viral myocarditis in children Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
Abstract
The invention relates to traditional Chinese medicine for treating damp-heat internal invasion type viral myocarditis in children. The medicine is prepared from alfalfa roots, isopirum auriculatum franch., celastrus gemmatus loes., cassia twigs, marsdenia longipes, bamboo leaves, hamate calanthe, Chinese dates, stauntonia latifolia and dendrobe. The traditional Chinese medicine can be clinically used for treating damp-heat internal invasion type viral myocarditis in children.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of treat damp and hot in invade the Chinese medicine of type infantile viral myocarditis.
Background technology
Viral myocarditis means the acute or chronic inflammatory disease of the cardiac muscle caused by various virus.Though pathological changes is based on cardiac muscle, also can involve pericardium and endocardium, clinically be more common in children's, be the major reason of child and Healthy Youth sudden death.Especially protracted course of disease person, due to the course of disease with the passing of time, pathogenesis change is very complicated, and deficiency and excess cold and heat, negative and positive of qi and blood, stasis of blood turbid pathogen poison is normal mutual for suffering from.Therefore, the deficiency and excess cold and heat of palpus shrewd pathological changes during treatment, righting is with eliminating evil.Invading the clinical manifestation of type infantile viral myocarditis in damp and hot is: pain uncomfortable in chest or the heavy and pain of the back of the body, breathe hard, cardiopalmus, dizziness, nausea and vomiting, abdominal distention, dark red fat large, the thick fur or greasy of tongue, rolling pulse slow or knot generation.Heart sign has cardiac dilatation, arrhythmia heart murmur, hear sounds low blunt etc.Because the pathogenesis of viral myocarditis still imperfectly understands, therefore, current doctor trained in Western medicine there is no specific treatment method, and adopt the symptomatic treatments such as immunosuppressant, interferon and myocardial cell nutrient clinical, permanence operation is bad more.Long-term practice through inventor draws, Chinese medicine control damp and hot in invade type infantile viral myocarditis there is better effect, obtain good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, damp and hot to the treatment of human non-toxic's side effect in invade the Chinese medicine of type infantile viral myocarditis.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizing the property of medicine of Chinese medicine uniqueness, adopting Radix Medicaginis, sow grass, Celastrus gemmatus Loes., Ramulus Cinnamomi, Radix Marsdeniae Longipedis, Folium Bambusae, Calanthe hamata-Mand (-Mazz), Fructus Jujubae, Fructus Akebiae, Herba Dendrobii according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine of the present invention to be made up of following raw material medicaments: Radix Medicaginis 30-40 part, sow grass 15-25 part, Celastrus gemmatus Loes. 15-25 part, Ramulus Cinnamomi 10-20 part, Radix Marsdeniae Longipedis 10-20 part, Folium Bambusae 10-20 part, Calanthe hamata-Mand (-Mazz) 10-20 part, Fructus Jujubae 10-20 part, Fructus Akebiae 10-20 part, Herba Dendrobii 5-10 part.
Optimum weight part of Chinese medicine of the present invention is: Radix Medicaginis 35 parts, sow grass 20 parts, Celastrus gemmatus Loes. 20 parts, Ramulus Cinnamomi 15 parts, Radix Marsdeniae Longipedis 15 parts, 15 parts, Folium Bambusae, Calanthe hamata-Mand (-Mazz) 15 parts, 15 parts, Fructus Jujubae, Fructus Akebiae 15 parts, Herba Dendrobii 8 parts.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix Medicaginis: bitter, cold.Return liver, kidney channel.Clearing away heat-damp and promoting diuresis, Tonglin Paishi.Clinical in calentura stuffy sensation with restlessness, jaundice, the diseases such as lithangiuria.
Sow grass: bitter, cold.Removing damp-heat, detoxicating and resolving stagnation of pathogens, relieving cough and resolving phlegm.Clinical in jaundice due to damp-heat, carbuncle sore tumefacting virus, scrofula, phlegm-heat cough, the diseases such as epilepsy.
Celastrus gemmatus Loes.: bitter, pungent, flat.Return liver, stomach warp.Expelling wind and removing dampness, promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling.Clinical in rheumatic arthralgia, traumatic injury, menoxenia, amenorrhea, puerperal abdonimal pain, stomachache, colic, sore, carbuncle and painful swelling, fracture, rubella, eczema, herpes zoster, venom.
Ramulus Cinnamomi: pungent, sweet, warm, GUIXIN, lung, urinary bladder channel.Diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI.For anemofrigid cold, congealing cold with blood stasis, phlegm retention, syndrome of water-retention.
Radix Marsdeniae Longipedis: sweet, micro-hardship, temperature.Return liver, kidney channel.Expelling wind and removing dampness, relievings asthma, promoting blood circulation to remove obstruction in the collateral.For rheumatic arthralgia, heart disease, bronchial asthma, traumatic injury, the diseases such as fracture.
Folium Bambusae: sweet, light, cold.Heat clearing away, relieving restlessness, diuresis.Cure mainly dysphoria with smothery sensation thirsty, aphtha of the mouth and tongue, gingival swelling and pain, children's's night crying due to fright in infant, hot urination, the diseases such as stranguria with turbid discharge.
Calanthe hamata-Mand (-Mazz): pungent, bitter, cold.Return liver, lung, kidney channel.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.Clinical in laryngopharynx swelling and pain, hemorrhoid, proctoptosis, rheumatic arthralgia, the diseases such as traumatic injury.
Fructus Jujubae: sweet, warm.Return spleen, stomach warp.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, relaxes the property of medicine.For insufficiency of the spleen anorexia and loose stool, fatigue and weakness, blood deficiency and yellow complexion and women's internal organs, mind is uneasy, protection healthy energy etc.
Fructus Akebiae: bitter, cool.Return bladder, the heart, Liver Channel.Clearing away heat-damp and promoting diuresis, blood circulation and channel invigorating, promoting the circulation of QI to relieve pain.For oliguria with reddish urine, stranguria with turbid discharge, edema, rheumatic arthralgia, traumatic injury, galactostasis, colicky, uterine prolapse, the diseases such as orchitis.
Herba Dendrobii: sweet, be slightly cold.Return stomach, lung, kidney channel.Promote the production of body fluid stomach reinforcing, nourishing YIN and clearing away heat, lung moistening kidney tonifying, the strong waist of improving eyesight.Clinical in consumption of body fluid caused by febrile disease, xerostomia excessive thirst, deficiency of stomach-Yin, stomachache is retched, dryness of the lung dry cough, and deficiency-heat is not moved back, and the moon hinders order secretly, and waist knee joint weakness waits disease.
Viral myocarditis belongs to motherland's medical science palpitation with fear, palpitation with a distress feeling, the thoracic obstruction, the sick category such as dizzy.Patient is many by ferritic virtual loss, the deficiency of both vital energy and Yin of the heart, so that after their early stage experiences seasonal pathogen, evil poison invasion, inside accumulates in the heart, the moon of more feeling frustrated immediately.Heresy is stayed and is not gone, and heart arteries and veins is impaired, hematogenous blockage.Radix Medicaginis clearing away heat-damp and promoting diuresis in the present invention, for monarch drug, sow grass removing damp-heat, removing toxic substances, Celastrus gemmatus Loes. expelling wind and removing dampness, detoxify, invigorate blood circulation, pain relieving, for ministerial drug, Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, removing toxic substances, Radix Marsdeniae Longipedis expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, Folium Bambusae heat clearing away, dehumidifying, Calanthe hamata-Mand (-Mazz) heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, Fructus Jujubae invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, Fructus Akebiae clearing away heat-damp and promoting diuresis, invigorate blood circulation, promoting the circulation of QI to relieve pain, Herba Dendrobii promotes the production of body fluid, nourishing YIN and clearing away heat.All medicines share, and find through clinical practice, in damp and hot, invade the curative effect that type infantile viral myocarditis has uniqueness.
Chinese medicine of the present invention invades the routine patient of type infantile viral myocarditis 83 in clinical observation in 2011 to 2014 is damp and hot, and clinical report is as follows:
1, physical data
In 83 routine patients, man 41 example, female 42 example, 7 ~ 17 years old age, the course of disease 5 days ~ 3 months.
2, diagnostic criteria
" Chinese medical disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
Invading the clinical manifestation of type infantile viral myocarditis in damp and hot is: aversion to wind and cold, cough, watery nasal discharge, headache, pharyngalgia, general malaise
。Less infant can now generate heat, and nasal obstruction, low voice speaking, uneasiness of crying and screaming, has pale complexion concurrently simultaneously, breathes hard, weak, hyperhidrosis.Larger child can state cardiopalmus, uncomfortable in chest, precordial pain, red tongue, thin fur, floating pulse imaginary number.
3, Therapeutic Method
3.1 prescriptions: Radix Medicaginis 35g, sow grass 20g, Celastrus gemmatus Loes. 20g, Ramulus Cinnamomi 15g, Radix Marsdeniae Longipedis 15g, Folium Bambusae 15g, Calanthe hamata-Mand (-Mazz) 15g, Fructus Jujubae 15g, Fructus Akebiae 15g, Herba Dendrobii 8g.
3.2 methods of preparation and use: said medicine routinely technique makes decoction, every day 1 dose, every day 2 times 15 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 formulate with reference to " clinical disease diagnosis is according to curing improvement standard ":
Cure: the symptoms such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma disappear completely, electrocardiogram recovers normal, and myocardium enzyme recovers normal, Color Sonography performance without exception.
Effective: the symptoms such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma significantly alleviate, and electrocardiogram recovers normal substantially, myocardium enzyme recovers normal, Color Sonography performance without exception.
Effective: the symptoms such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma alleviate, electrocardiogram mile abnormality, myocardium enzyme recovers normal, Color Sonography mile abnormality.
Invalid: the symptom such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma does not alleviate, and electrocardiographic abnormality does not improve, myocardium enzyme is not improved, and Color Sonography does not improve.
4.2 results: in 83 routine patients, cure 46 examples (55.4%), effective 21 examples (25.3%), effective 11 examples (13.3%), and invalid 5 examples (6.0%), total effective rate is 94%.
5, model case
In 5.1 seasons, 11 years old, there is headache, heating, uncomfortable in chest, cardio palmus shape in man after catching a cold.White with complexion Anhui, dizzy weak, the listless and aching speech of limb, sensation of oppression over the chest with shortness of breath, time had palpitation, spontaneous perspiration, red tongue, greasy fur, rolling pulse delays, and time only has a rest.Be diagnosed as damp and hot in invade type infantile viral myocarditis.Take medicine of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, and cardiopalmus, attack times uncomfortable in chest obviously reduce, and continues to take 2 courses for the treatment of, recovery from illness, follows up a case by regular visits to without recurrence after half a year.
5.2 money, female, 10 years old, because cold, fever does not move back, red and the pain of companion's pharynx, dizzy weak, hospitalization, through with after the symptomatic treatment such as antibiotic and transfusion l week, body temperature is down to normally, and pharyngalgia is also removed, but time have cough, weak with dizziness, the listless and aching speech of limb, sensation of oppression over the chest with shortness of breath, time had palpitation, stool the pool soft, poor appetite, light red tongue, thick fur, rolling pulse delays, and time only has a rest.Be diagnosed as damp and hot in invade type infantile viral myocarditis.Take medicine of the present invention, every day 1 dose, after 1 course for the treatment of, symptom is clearly better, and continues to take 2 courses for the treatment of, recovery from illness, follows up a case by regular visits to without recurrence after 1 year.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, a kind of treat damp and hot in invade the Chinese medicine of type infantile viral myocarditis, be made up of Radix Medicaginis 30g, sow grass 15g, Celastrus gemmatus Loes. 15g, Ramulus Cinnamomi 10g, Radix Marsdeniae Longipedis 10g, Folium Bambusae 10g, Calanthe hamata-Mand (-Mazz) 10g, Fructus Jujubae 10g, Fructus Akebiae 10g, Herba Dendrobii 5g.
Embodiment 2, a kind of treat damp and hot in invade the Chinese medicine of type infantile viral myocarditis, be made up of Radix Medicaginis 35g, sow grass 20g, Celastrus gemmatus Loes. 20g, Ramulus Cinnamomi 15g, Radix Marsdeniae Longipedis 15g, Folium Bambusae 15g, Calanthe hamata-Mand (-Mazz) 15g, Fructus Jujubae 15g, Fructus Akebiae 15g, Herba Dendrobii 8g.
Embodiment 3, a kind of treat damp and hot in invade the Chinese medicine of type infantile viral myocarditis, be made up of Radix Medicaginis 40g, sow grass 25g, Celastrus gemmatus Loes. 25g, Ramulus Cinnamomi 20g, Radix Marsdeniae Longipedis 20g, Folium Bambusae 20g, Calanthe hamata-Mand (-Mazz) 20g, Fructus Jujubae 20g, Fructus Akebiae 20g, Herba Dendrobii 10g.
Claims (2)
1. treat damp and hot in invade the Chinese medicine of type infantile viral myocarditis, it is characterized in that its crude drug comprises following medicine:
Radix Medicaginis 30-40 part, sow grass 15-25 part, Celastrus gemmatus Loes. 15-25 part, Ramulus Cinnamomi 10-20 part,
Radix Marsdeniae Longipedis 10-20 part, Folium Bambusae 10-20 part, Calanthe hamata-Mand (-Mazz) 10-20 part, Fructus Jujubae 10-20 part,
Fructus Akebiae 10-20 part, Herba Dendrobii 5-10 part.
2. Chinese medicine according to claim 1, is characterized in that its crude drug comprises following medicine:
Radix Medicaginis 35 parts, sow grass 20 parts, Celastrus gemmatus Loes. 20 parts, Ramulus Cinnamomi 15 parts,
Radix Marsdeniae Longipedis 15 parts, 15 parts, Folium Bambusae, Calanthe hamata-Mand (-Mazz) 15 parts, 15 parts, Fructus Jujubae,
Fructus Akebiae 15 parts, Herba Dendrobii 8 parts.
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| CN201510936581.4A CN105327197A (en) | 2015-12-16 | 2015-12-16 | Traditional Chinese medicine for treating damp-heat internal invasion type viral myocarditis in children |
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| CN201510936581.4A CN105327197A (en) | 2015-12-16 | 2015-12-16 | Traditional Chinese medicine for treating damp-heat internal invasion type viral myocarditis in children |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1513542A (en) * | 2002-12-31 | 2004-07-21 | 天津天士力制药股份有限公司 | Chinese medicinal preparation for treating viral myocarditis and its making method |
| CN102488838A (en) * | 2011-12-26 | 2012-06-13 | 中国人民解放军第三军医大学第二附属医院 | Traditional Chinese medicine composition used for treating viral myocarditis |
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2015
- 2015-12-16 CN CN201510936581.4A patent/CN105327197A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1513542A (en) * | 2002-12-31 | 2004-07-21 | 天津天士力制药股份有限公司 | Chinese medicinal preparation for treating viral myocarditis and its making method |
| CN102488838A (en) * | 2011-12-26 | 2012-06-13 | 中国人民解放军第三军医大学第二附属医院 | Traditional Chinese medicine composition used for treating viral myocarditis |
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