CN105326714A - Skin aging-resistant cosmetics and preparation method thereof - Google Patents
Skin aging-resistant cosmetics and preparation method thereof Download PDFInfo
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- CN105326714A CN105326714A CN201510855609.1A CN201510855609A CN105326714A CN 105326714 A CN105326714 A CN 105326714A CN 201510855609 A CN201510855609 A CN 201510855609A CN 105326714 A CN105326714 A CN 105326714A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The invention relates to skin aging-resistant cosmetics, and belongs to the filed of cosmetics. The skin aging-resistant cosmetics are prepared from herba dendrodii officinalis, radix paeoniae allba, bletilla striata, gingko, poria cocos, ligusticum chuanxiong, pericarpium citri reticulatae, astragali radix, liriope, hippophae rhamnoides, semen pruni, polygonum viviparum and cornus officinalis and are prepared through the steps of decocting, filtering, concentrating and the like. The skin aging-resistant cosmetics disclosed by the invention have the effects of restraining melanocytes and tyrosinase and resisting free radicals.
Description
Technical field
The present invention relates to a kind of anti aging effect cosmetics, belong to cosmetic field.
Background technology
It is generally acknowledged, the action effect of anti aging effect active substance comprises scavenging free radicals, improves cell proliferation rate, delays the degradation speed of extracellular matrix.Meanwhile, anti-aging cosmetics needs to select excellent skin-care agent, supplements enough nutrients, reach deep layer nutrition to skin.In addition, the loss of moisture in skin to also be slowed down, protection skin.
At present, all there is very large defect in the management of China's cosmetics and technology, and the phenomenon of adding in violation of rules and regulations is very serious, causes many beauty treatment accidents for many years, causes very large injury to consumer, has caused the great attention of country and consumer.Exploitation has good safety, stability, successful, natural anti-aging cosmetics that cost performance is good, has extraordinary development prospect.Natural materials is applied to cosmetics can reach skin treating and skin protection double effects, and has diverse in function, the characteristic such as widely applicable, safe, is thus subject to attention day by day.
Summary of the invention
The object of the invention is to the toxic and side effects avoiding chemosynthesis additive, provide a kind of compositions being derived from natural, that safety is high, effective anti aging effect, also provide that the present invention is said can the preparation method of anti aging effect cosmetics simultaneously.
In order to realize above-mentioned goal of the invention, the invention provides following technical scheme:
A kind of anti aging effect cosmetics, be made up of the raw material of following parts by weight:
Herba Dendrobii 4 ~ 8 parts, the Radix Paeoniae Alba 6 ~ 9 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 5 ~ 7 parts, Semen Ginkgo 4 ~ 6 parts, 6 ~ 8 parts, Poria, Rhizoma Chuanxiong 6 ~ 8 parts, Pericarpium Citri Reticulatae 1 ~ 3 part, the Radix Astragali 4 ~ 6 parts, Radix Ophiopogonis 5 ~ 7 parts, Fructus Hippophae 2 ~ 4 parts, Semen Pruni 2 ~ 4 parts, Rhizoma Polygoni suffulti 5 ~ 7 parts, Fructus Corni 1 ~ 3 part.
Preferably: Herba Dendrobii 6 parts, the Radix Paeoniae Alba 7 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 6 parts, Semen Ginkgo 5 parts, 7 parts, Poria, Rhizoma Chuanxiong 7 parts, Pericarpium Citri Reticulatae 2 parts, the Radix Astragali 5 parts, Radix Ophiopogonis 6 parts, Fructus Hippophae 3 parts, Semen Pruni 3 parts, Rhizoma Polygoni suffulti 6 parts, Fructus Corni 2 parts.
The preparation method of above-mentioned anti aging effect cosmetics is:
1) get formula ratio raw material and decoct with water twice, filter and collect filtrate;
2) by step 1) gained filtrate when being concentrated into 70 ~ 80 DEG C relative density be the magma of 1.18 ~ 1.26;
3) toward step 2) add chitosan in gained magma, make containing 1.1 ~ 1.6g chitosan in every 1000mL magma, insulation leaves standstill, and filters and collects filtrate;
4) by step 3) gained filtrate concentrates, makes in every milliliter of extracting solution containing 2.0 ~ 3.0g crude drug;
5) by step 4) gained extracting solution is configured to required State of cosmetics.
Preferably: described step 1), it is 5 ~ 7 times of raw material weights that first time decocts water consumption, and it is 3 ~ 5 times of raw material weights that second time decocts water consumption.
Described State of cosmetics is essence, skin protection condensation, emulsion.
The effect that there are anti-senescence function cosmetics and there is check melanin cell, suppress white horse with a black mane propylhomoserin enzyme, free radical resisting of the present invention.Effectively can generate by check melanin, skin obfuscation can be alleviated, chloasma, wrinkle increase, insomnia and dreamful sleep, hectic fever night sweat, Glycerin etc.Meanwhile, said composition is not containing chemosynthesis material, and have no side effect, skin irritation is little, and stable in properties is safe and reliable.Except having anti-senescence function, because said composition contains many important component, have the functions such as antiinflammatory is antibacterial, can promote skin metabolism, the nutrition improving skin, with healthy, has good skin effect.
Detailed description of the invention
Further describe technical scheme of the present invention below, but described in claimed scope is not limited to.Below in conjunction with specific embodiment, elaboration detailed is further done to the present invention, but embodiments of the present invention are not limited to the scope that embodiment represents.These embodiments only for illustration of the present invention, but not for limiting the scope of the invention.In addition, after reading content of the present invention, those skilled in the art can do various amendment to the present invention, and these equivalent variations fall within appended claims limited range of the present invention equally.
Embodiment 1
Raw material is got according to following weight (kilogram) proportioning:
Herba Dendrobii 4 Radix Paeoniae Alba 6 Pseudobulbus Bletillae (Rhizoma Bletillae) 5 Semen Ginkgo 4 Poria 6 Rhizoma Chuanxiong 6 Pericarpium Citri Reticulatae 1 Radix Astragali 4 Radix Ophiopogonis 5 Fructus Hippophae 2 Semen Pruni 2 Rhizoma Polygoni suffulti 5 Fructus Corni 1.
Above-mentioned raw materials is dipped in 255 kg water and decocts 90 minutes, collecting by filtration filtrate.Be dipped in by gained filtering residue in 153 kg water and decoct 50 minutes, collecting by filtration filtrate, merges twice gained filtrate.Gained filtrate being concentrated into 70 DEG C of relative densities is the magma of 1.18.In magma, add chitosan, make containing 1.1g chitosan in every 1000mL magma, fully stir, insulation leaves standstill, and filters and collects filtrate.Gained filtrate is concentrated, makes in every milliliter of extracting solution containing 2.0g crude drug.Gained finished product can be made essence dosage form as required and use.
Embodiment 2
Raw material is got according to following weight (kilogram) proportioning:
Herba Dendrobii 6 Radix Paeoniae Alba 7 Pseudobulbus Bletillae (Rhizoma Bletillae) 6 Semen Ginkgo 5 Poria 7 Rhizoma Chuanxiong 7 Pericarpium Citri Reticulatae 2 Radix Astragali 5 Radix Ophiopogonis 6 Fructus Hippophae 3 Semen Pruni 3 Rhizoma Polygoni suffulti 6 Fructus Corni 2.
Above-mentioned raw materials is dipped in 390 kg water and decocts 95 minutes, collecting by filtration filtrate.Be dipped in by gained filtering residue in 260 kg water and decoct 60 minutes, collecting by filtration filtrate, merges twice gained filtrate.Gained filtrate being concentrated into 75 DEG C of relative densities is the magma of 1.2.In magma, add chitosan, make containing 1.3g chitosan in every 1000mL magma, fully stir, insulation leaves standstill, and filters and collects filtrate.Gained filtrate is concentrated, makes in every milliliter of extracting solution containing 2.5g crude drug.Gained finished product can use as beauty essence, skin protection condensation, emulsion.
Embodiment 3
Raw material is got according to following weight (kilogram) proportioning:
Herba Dendrobii 8 Radix Paeoniae Alba 9 Pseudobulbus Bletillae (Rhizoma Bletillae) 7 Semen Ginkgo 6 Poria 8 Rhizoma Chuanxiong 8 Pericarpium Citri Reticulatae 3 Radix Astragali 6 Radix Ophiopogonis 7 Fructus Hippophae 4 Semen Pruni 4 Rhizoma Polygoni suffulti 7 Fructus Corni 2.
Above-mentioned raw materials is dipped in 553 kg water and decocts 100 minutes, collecting by filtration filtrate.Be dipped in by gained filtering residue in 395 kg water and decoct 60 minutes, collecting by filtration filtrate, merges twice gained filtrate.Gained filtrate being concentrated into 80 DEG C of relative densities is the magma of 1.26.In magma, add chitosan, make containing 1.6g chitosan in every 1000mL magma, fully stir, insulation leaves standstill, and filters and collects filtrate.Gained filtrate is concentrated, makes in every milliliter of extracting solution containing 3.0g crude drug.Gained finished product can use as beauty essence, skin protection condensation, emulsion.
It is below cosmetics anti aging effect effect experimental of the present invention
After obtaining magma according to the method for embodiment example 1, carry out dried, obtained flour, adds 10 weight distilled water, heating and refluxing extraction 3 times, each 1 hour.Merging filtrate, sucking filtration.Filtrate reduced in volume, places, removing precipitation, and supernatant, by D101 macroporous resin eluting, collects 70% ethanol elution, and reduced vacuum concentrates, and obtains Chinese medicine extract.Extract is made into the sample solution that concentration is 1%, tests below carrying out.
1, the mensuration of restraint of tyrosinase vigor
According to following table (table 1) application of sample, do not add tryrosinase, 1% arbutin is contrasted as one group of sample.After solution being placed in 37 DEG C of water-bath constant temperature 10min, under 475nm, measuring its absorbance, and compare with 1% arbutin.
Table 1
By formula (1) calculation sample to the relative inhibition of tryrosinase.
Suppression ratio=[(A
1-A
2)-(A
3-A
4)]/(A
1-A
2)
In formula: A
1, A
2, A
3, A
4be respectively the absorbance of 1 group to 4 groups.
2, the mensuration of ultra-oxygen anion free radical scavenging action
Get the Tris-HCl buffer 4.5 milliliters of 0.05mol/LpH=8.2, preheating 20min in 25 DEG C of water-baths, is adding the neck benzenetriol solution of 1mL sample and 0.4mL25mmol/L, after mixing, in 25 DEG C of water-baths, react 5min, add the HCl1.0mL cessation reaction of 8mol/L.Make reference with Tris-HCl buffer, survey absorbance at 299nm place.The solvent of blank 1mL sample carrys out alternative sample.Clearance rate (D) is calculated according to formula (2).
Clearance rate (%)=[1-(A
2/ A
1)] × 100% formula (2)
A in formula
1for the absorbance of blank; A
2for the absorbance of medicine.
3, the Scavenging activity of hydroxy radical is measured
2mmol/LFeSO is added successively in 25mL color comparison tube
43mL, 1mmol/LH
2o
23mL, shakes up, and then adds 6mmol/L salicylic acid 3mL, shakes up, take out after 37 DEG C of heating in water bath 15min, measures absorbance; Add certain density liquid to be measured respectively, shake up, continue heating in water bath 15min, take out and measure its absorbance.Following formula (3) is for liquid to be measured is to the clearance rate of carboxylic free radical (OH):
OH clearance rate (%)=[A
1-A
2-(A
1-A
3)]/A
1× 100% formula (3)
A in formula
1for not adding the absorbance of reaction system before medicine; A
2for OH removed by medicine
The absorbance of rear system; A
3for system absorbance after blank clearance rate OH.Shown in anti-senescence function evaluation experimental following (table 2).
Table 2 anti-senescence function experimental result
| Experimental project | Suppression ratio (%) |
| Restraint of tyrosinase vigor | 85.7 |
| To superoxide anion scavenging action | 65.8 |
| To Hydroxyl Radical Scavenging | 80.2 |
Experiment shows, Chinese medicine composition of the present invention can the activity of restraint of tyrosinase effectively, has the function of scavenging free radicals simultaneously, and then realizes antidotal effect.
Claims (5)
1. anti aging effect cosmetics, is characterized in that, it is made up of the raw material of following parts by weight:
Herba Dendrobii 4 ~ 8 parts, the Radix Paeoniae Alba 6 ~ 9 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 5 ~ 7 parts, Semen Ginkgo 4 ~ 6 parts, 6 ~ 8 parts, Poria, Rhizoma Chuanxiong 6 ~ 8 parts, Pericarpium Citri Reticulatae 1 ~ 3 part, the Radix Astragali 4 ~ 6 parts, Radix Ophiopogonis 5 ~ 7 parts, Fructus Hippophae 2 ~ 4 parts, Semen Pruni 2 ~ 4 parts, Rhizoma Polygoni suffulti 5 ~ 7 parts, Fructus Corni 1 ~ 3 part.
2. anti aging effect cosmetics according to claim 1, is characterized in that, described cosmetics are made up of the raw material of following parts by weight:
Herba Dendrobii 6 parts, the Radix Paeoniae Alba 7 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 6 parts, Semen Ginkgo 5 parts, 7 parts, Poria, Rhizoma Chuanxiong 7 parts, Pericarpium Citri Reticulatae 2 parts, the Radix Astragali 5 parts, Radix Ophiopogonis 6 parts, Fructus Hippophae 3 parts, Semen Pruni 3 parts, Rhizoma Polygoni suffulti 6 parts, Fructus Corni 2 parts.
3. the preparation method of anti aging effect cosmetics described in claim 1 or 2, is characterized in that, comprise the following steps:
1) get formula ratio raw material and decoct with water twice, filter and collect filtrate;
2) by step 1) gained filtrate when being concentrated into 70 ~ 80 DEG C relative density be the magma of 1.18 ~ 1.26;
3) toward step 2) add chitosan in gained magma, make containing 1.1 ~ 1.6g chitosan in every 1000mL magma, insulation leaves standstill, and filters and collects filtrate;
4) by step 3) gained filtrate concentrates, makes in every milliliter of extracting solution containing 2.0 ~ 3.0g crude drug;
5) by step 4) gained extracting solution is configured to required State of cosmetics.
4. anti aging effect cosmetics according to claim 3, is characterized in that, described step 1) in, it is 5 ~ 7 times of raw material weights that first time decocts water consumption, and it is 3 ~ 5 times of raw material weights that second time decocts water consumption.
5. anti aging effect cosmetics according to claim 3, is characterized in that, described State of cosmetics is essence, skin protection condensation, emulsion.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510855609.1A CN105326714A (en) | 2015-11-28 | 2015-11-28 | Skin aging-resistant cosmetics and preparation method thereof |
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| CN201510855609.1A CN105326714A (en) | 2015-11-28 | 2015-11-28 | Skin aging-resistant cosmetics and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107638516A (en) * | 2017-11-08 | 2018-01-30 | 广州市络捷生物科技有限公司 | A kind of slowing down skin aging Chinese medicine composition and preparation method thereof |
| CN108261365A (en) * | 2018-02-07 | 2018-07-10 | 赵利 | A kind of cosmetics treated and improve problem skin |
| CN108338955A (en) * | 2018-05-23 | 2018-07-31 | 云南中丹红制药有限责任公司 | A kind of cosmetics and preparation method thereof |
| CN108403558A (en) * | 2018-05-08 | 2018-08-17 | 江西轩斛生物科技有限公司 | A kind of dendrobium candidum mask product |
| CN109010220A (en) * | 2018-10-19 | 2018-12-18 | 贵州真阳纳米医药科技有限公司 | A kind of cosmetic composition and preparation method thereof |
| CN109157501A (en) * | 2018-09-25 | 2019-01-08 | 深圳市宝迪生物工程有限公司 | A kind of composition of the anti-aging of the extract containing stem cell and application |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107638516A (en) * | 2017-11-08 | 2018-01-30 | 广州市络捷生物科技有限公司 | A kind of slowing down skin aging Chinese medicine composition and preparation method thereof |
| CN107638516B (en) * | 2017-11-08 | 2021-05-11 | 广州市络捷生物科技有限公司 | Traditional Chinese medicine composition for slowing down skin aging and preparation method thereof |
| CN108261365A (en) * | 2018-02-07 | 2018-07-10 | 赵利 | A kind of cosmetics treated and improve problem skin |
| CN108403558A (en) * | 2018-05-08 | 2018-08-17 | 江西轩斛生物科技有限公司 | A kind of dendrobium candidum mask product |
| CN108338955A (en) * | 2018-05-23 | 2018-07-31 | 云南中丹红制药有限责任公司 | A kind of cosmetics and preparation method thereof |
| CN109157501A (en) * | 2018-09-25 | 2019-01-08 | 深圳市宝迪生物工程有限公司 | A kind of composition of the anti-aging of the extract containing stem cell and application |
| CN109010220A (en) * | 2018-10-19 | 2018-12-18 | 贵州真阳纳米医药科技有限公司 | A kind of cosmetic composition and preparation method thereof |
| CN109010220B (en) * | 2018-10-19 | 2021-10-01 | 贵州真阳纳米医药科技有限公司 | Cosmetic composition and preparation method thereof |
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Application publication date: 20160217 |