CN103976912B - A kind of Herba Piperris Tonkinensis extracting solution and its preparation method and application - Google Patents

A kind of Herba Piperris Tonkinensis extracting solution and its preparation method and application Download PDF

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CN103976912B
CN103976912B CN201410238162.9A CN201410238162A CN103976912B CN 103976912 B CN103976912 B CN 103976912B CN 201410238162 A CN201410238162 A CN 201410238162A CN 103976912 B CN103976912 B CN 103976912B
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extracting solution
herba piperris
piperris tonkinensis
tonkinensis
herba
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CN103976912A (en
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杨广群
谢丽萍
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Guangdong Da'ao Biotechnology Co.,Ltd.
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Guangzhou Danqi Daily Chemical Co Ltd
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Abstract

The invention discloses a kind of Herba Piperris Tonkinensis extracting solution and its preparation method and application. The Herba Piperris Tonkinensis extracting solution that the present invention obtains through refining through water, it has the effect of significant antiinflammatory of calming, scattered fire detumescence, convergence, transdermal promotion assimilation effect and suppression pathogen, this characteristic makes Herba Piperris Tonkinensis extracting solution possess antipruritic, pain relieving, antibacterial effectiveness, simultaneously work as skin lesion caused by anti-relieving itching and cause the effect of infection, be applied in cosmetics and there is significant antiallergic itching-relieving efficacies.

Description

A kind of Herba Piperris Tonkinensis extracting solution and its preparation method and application
Technical field
The present invention relates to cosmetic field, particularly relate to a kind of Herba Piperris Tonkinensis extracting solution and its preparation method and application.
Background technology
Raising along with people's consumption consciousness and concept of health, go back to nature, select both safe and effective medical cosmetology skin care item, just becoming a kind of fashion trend in beauty and skin care field at present, healthy skin needs moisture to nourish, with greater need for the care of safe skin care ingredient, and the medical science skin-protection product being added with pro-skin natural plant composition targetedly is undoubtedly best selection. Natural plant kind skin-protection product also because of its use safety, action temperature and, the advantage such as effect is obvious and be subject to the parent of consumers in general and look at. Obtain the plant extract containing effective ingredient generally by corresponding processing, and add in cosmetics.
Plant extract in current cosmetics, mostly adopts water to carry, alcohol extraction, ultrasonic extraction, the method such as microwave extraction extract gained, and extraction process is complicated, through operations such as concentrate dryings, also to add preservative so that the shelf-life of extract is more permanent. The drawback so brought, one is waste resource, and in extraction process, solution concentrates, and generally only takes concentration fraction elite out, and most solutions then discards. This part solution is possibly together with other effective ingredient in fact, it is possible to again with, and directly discard the waste having resulted in resource. Another drawback is, adds preservative and extract no doubt can be made to obtain the longer shelf-life, but also bring sensitization source for skin simultaneously in extract.
Pruritus is the conscious state of one that many dermatosiss are total. Its pathogenic factor is very complicated, has internal factor, as dysbolismus, endocrine dysfunction, internal damp and hot must not catharsis, Enterozoa etc.; Also there is environmental stimuli factor, the skin allergy that causes such as climate change, dry, external used medicine allergy, eat pungent stimulation food etc. Due to violent pruritus, constantly scratch, it is possible to scratching of scratch, blood crusts or strip occurs, sometimes have eczema sample to change, lichenification or pigmentation. The skin scratched also easily infects and furuncle and phyma or folliculitis occurs.
Therefore, select which kind of plant, how simply, safely, effectively to this plant extract to carry out, and be applied in cosmetics to prevent skin lesion caused by skin pruritus and pruritus and the infection that causes by its safety, be problem demanding prompt solution.
Summary of the invention
Based on this, present invention aim at providing a kind of Herba Piperris Tonkinensis extracting solution and its preparation method and application.
The concrete technical scheme solving above-mentioned technical problem is as follows:
The preparation method of a kind of Herba Piperris Tonkinensis extracting solution, comprises the following steps:
By Herba Piperris Tonkinensis drying and crushing, install with the 800-1000 order gauze bag of sterilizing, be placed in vacuum emulsifying pot, by the weight of Herba Piperris Tonkinensis, add the deionized water of 8-12 times amount, in 90-100 DEG C of extraction, can be prepared by Herba Piperris Tonkinensis extracting solution.
Wherein in some embodiments, the time of described extraction is 20-50min.
Wherein in some embodiments, by Herba Piperris Tonkinensis drying and crushing, installing with the 800-1000 order gauze bag of sterilizing, be placed in vacuum emulsifying pot, after having extracted, directly taken out by gauze bag, remaining solution is Herba Piperris Tonkinensis extracting solution. Owing to adopting vacuum emulsifying pot in the method, other cosmetic after extraction completes, directly can be added by it, carries out Cosmetic Manufacture, extracts without with special herbal extraction equipment, has saved cost; It addition, adopt the packed Herba Piperris Tonkinensis powder of gauze, directly gauze bag is taken out after having extracted, need not filter, simplify extraction process, improve efficiency.
Said method is simple to operation, and Herba Piperris Tonkinensis extract can now be withdrawn deposit use, does not need to add preservative, substantially reduces the sensitization source to skin. In cosmetic formulations, inherently it is added with preservative, extract of the present invention is now carried and adds, it is to avoid produce spoilage problems because of placement.
Herba Piperris Tonkinensis extracting solution obtained by said method has the application in the cosmetics of antiallergic itching-relieving efficacies in preparation.
Wherein in some embodiments, in described cosmetics, the content of Herba Piperris Tonkinensis extracting solution is 58-95wt%.
Wherein in some embodiments, described cosmetics are body lotion.
The present invention provides a kind of body lotion, and described body lotion includes the component of following weight percentage ratio:
Emulsifying agent: 3.0-7.0wt%,
Emollient: 2.0-7.0wt%,
Skinfeel regulator: 5.0-12.0wt%,
Thickening agent: 0.2-0.4wt%,
Wetting agent: 4-9wt%,
Preservative: 0.2-0.8wt%,
Herba Piperris Tonkinensis extracting solution as claimed in claim 2: surplus;
Described emulsifying agent is at least one in methyl sesquistearate, PEG-20 methyl sesquistearate, cetearyl alcohol, sodium lauryl sulfate or glyceryl stearate/PEG-100 stearate;
Described emollient is at least one in isopropyl palmitate, caprylic/capric triglyceride or hydrogenated jojoba oil;
Described skinfeel regulator is at least one in ring five polydimethylsiloxane/cyclohexasiloxane, polydimethylsiloxane or vinyldimethicone/polymethyl siloxane silsesquioxane cross linked polymer;
Described thickening agent is at least one in xanthan gum, hydroxyethyl cellulose or carbomer;
Described wetting agent is at least one in propylene glycol, glycerol or butanediol;
Described preservative is at least one in Bis(hydroxymethyl)imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate, propyl hydroxybenzoate or methyl hydroxybenzoate.
Wherein in some embodiments, described body lotion includes the component of following weight percentage ratio:
Emulsifying agent: 3.0-7.0wt%,
Emollient: 2.0-7.0wt%,
Skinfeel regulator: 5.0-12.0wt%,
Thickening agent: 0.2-0.4wt%,
Wetting agent: 4-9wt%,
Preservative: 0.2-0.8wt%,
The Herba Piperris Tonkinensis extracting solution that above-mentioned preparation method prepares: surplus;
Described emulsifying agent is at least one in methyl sesquistearate, PEG-20 methyl sesquistearate, cetearyl alcohol or glyceryl stearate/PEG-100 stearate;
Described emollient is isopropyl palmitate;
Described skinfeel regulator is at least one in ring five polydimethylsiloxane/cyclohexasiloxane or polydimethylsiloxane;
Described thickening agent is xanthan gum;
Described wetting agent is at least one in propylene glycol, butanediol;
Described preservative is Bis(hydroxymethyl)imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate.
Wherein in some embodiments, described body lotion includes the component of following weight percentage ratio:
Methyl sesquistearate: 1.3-2.0wt%,
PEG-20 methyl sesquistearate: 0.5-1.5wt%,
Isopropyl palmitate: 2-6wt%,
Ring five polydimethylsiloxane/cyclohexasiloxane: 3.0-8.0wt%,
Glyceryl stearate/PEG-100 stearate: 0.5-1.5wt%,
Cetearyl alcohol: 0.8-1.6wt%,
Polydimethylsiloxane: 2.0-3.5wt%,
Methyl hydroxybenzoate: 0.15-0.25wt%,
Propyl hydroxybenzoate: 0.05-0.14wt%,
Xanthan gum: 0.15-0.35wt%,
Propylene glycol: 4-8wt%,
Bis(hydroxymethyl)imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate: 0.1-0.3wt%,
Above-mentioned Herba Piperris Tonkinensis extracting solution: surplus.
A kind of Herba Piperris Tonkinensis extracting solution of the present invention and its preparation method and application has the following advantages and beneficial effect:
The present invention is through the substantial amounts of experiment of inventor and research, draw and put obtained Herba Piperris Tonkinensis extracting solution at optimum process water, it has the effect of significant antiinflammatory of calming, scattered fire detumescence, convergence, transdermal promotion assimilation effect and suppression pathogen, this characteristic makes Herba Piperris Tonkinensis extracting solution possess antipruritic, pain relieving, antibacterial effectiveness, simultaneously work as skin lesion caused by anti-relieving itching and cause the effect of infection, be applied in cosmetics and there is significant antiallergic itching-relieving efficacies.
Detailed description of the invention
Herba Piperris Tonkinensis of the present invention is Piperaceae Piper plant optical axis ramie leaf, is used as medicine with root or Herb, is born in the dark gully of high mountains and dense forests, is distributed the ground such as Guangdong, Guangxi, Yunnan. Herba Piperris Tonkinensis acrid in the mouth is warm in nature, has expelling wind and cold; Promoting blood flow to regulate menstruation; Reducing swelling and alleviating pain effect, poisonous snake, centipete bite are controlled in external. Guangzhou army " conventional Chinese herbal medicine handbook ": " expelling wind and cold, repercussive pain relieving. Dispelling the wind and dampness pathogens bones and muscles pain, treating swelling and pain by traumatic injury, cold syndrome of the stomach pain; Poisonous snake, centipete bite. " 2. " choosing of Yunnan Chinese herbal medicine ": " control dysmenorrhea, amenorrhea, Common Cold. " Herba Piperris Tonkinensis obtained through refining to obtain Herba Piperris Tonkinensis extracting solution through water by the present invention, use it for preparation and have in antiallergic itching-relieving efficacies cosmetics.
Below with reference to specific embodiment, the present invention will be further described.
In following embodiment, described raw material is commercially available prod.
Components Name used in following example is international cosmetic raw material name (InternationalNomenclatureCosmeticIngredient, INCI) title of defined, for instance glyceryl stearate/PEG-100 stearate, ring five polydimethylsiloxane/cyclohexasiloxane, Bis(hydroxymethyl)imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate.
Embodiment 1 body lotion
Containing Herba Piperris Tonkinensis extracting solution in body lotion described in the present embodiment, the preparation method of described Herba Piperris Tonkinensis extracting solution, comprises the following steps: is cleaned by 1 kilogram of Herba Piperris Tonkinensis, dries, drying and crushing is to 60 orders, install with 900 order gauze bags of sterilizing, be placed in vacuum emulsifying pot, add the deionized water of 8 kilograms, in 95 DEG C of lixiviate 30min, gauze bag is taken out, remaining solution, obtain Herba Piperris Tonkinensis extracting solution.
The component of described body lotion and content are in Table 1:
The component of table 1 body lotion and content
Comparative example 1 body lotion
The component of described body lotion and content are in Table 2:
The component of table 2 body lotion and content
Embodiment 2 efficacy assessments
One, experiment purpose
By the effect that the antiallergic of cosmetics obtained in relative analysis evaluation the various embodiments described above is antipruritic.
Two, experimental technique
This experiment is divided into experimental group and matched group, and wherein, experimental group is: embodiment 1-body lotion; Matched group is comparative example 1-body lotion, a certain commercially available has the body lotion that antiallergic is antipruritic.
Collect 200 volunteers and try out above-mentioned each product 30 days, after trier uses identical cleaning agent to clean face, about trier face, selected same area is as trial zone, and embodiment product is smeared in left side, the corresponding comparative example product of equivalent, observed result are smeared in right side. Wherein, women 120 people, male 80 people, max age 65 years old, minimal ages 10 years old.
The main manifestations of described allergy pruritus skin is: the symptoms such as redness, skin injury, inflammation occurs in skin pruritus scratching.
Three, experimental result
Result is referring to table 3.
The efficacy outcomes table of table 3 experimental group and matched group
As known from Table 3: skin pruritus scratching is occurred that redness, skin injury, inflammation all have improvement in various degree by matched group product and comparative example 1-body lotion, a certain commercially available body lotion and experimental group product embodiments 1-body lotion, can be seen that from experimental data, in experimental group product to skin pruritus scratching and occur redness, skin injury, inflammation improvement degree substantially high than the improvement degree of product in matched group, it follows that the cosmetics containing Herba Piperris Tonkinensis extracting solution have effect that significant antiallergic is antipruritic.
Embodiment described above only have expressed the several embodiments of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention. It should be pointed out that, for the person of ordinary skill of the art, without departing from the inventive concept of the premise, it is also possible to making some deformation and improvement, these broadly fall into protection scope of the present invention. Therefore, the protection domain of patent of the present invention should be as the criterion with claims.

Claims (4)

1. Herba Piperris Tonkinensis extracting solution has the application in the cosmetics of antiallergic itching-relieving efficacies in preparation, the preparation method of described Herba Piperris Tonkinensis extracting solution comprises the following steps: dried by Herba Piperris Tonkinensis, pulverize, load the 800-1000 order gauze bag of sterilizing, it is placed in vacuum emulsifying pot, by the weight of Herba Piperris Tonkinensis, adds the deionized water of 8-12 times amount, in 90-100 DEG C of extraction.
2. application according to claim 1, it is characterised in that in described cosmetics, the content of Herba Piperris Tonkinensis extracting solution is 58-95wt%.
3. application according to claim 1 and 2, it is characterised in that described cosmetics are body lotion.
4. application according to claim 3, it is characterised in that described body lotion includes the component of following weight percentage ratio:
Emulsifying agent: 3.0-7.0wt%,
Emollient: 2.0-7.0wt%,
Skinfeel regulator: 5.0-12.0wt%,
Thickening agent: 0.2-0.4wt%,
Wetting agent: 4-9wt%,
Preservative: 0.2-0.8wt%,
Herba Piperris Tonkinensis extracting solution as claimed in claim 2: surplus;
Described emulsifying agent is at least one in methyl sesquistearate, PEG-20 methyl sesquistearate, cetearyl alcohol, sodium lauryl sulfate or glyceryl stearate/PEG-100 stearate;
Described emollient is at least one in isopropyl palmitate, caprylic/capric triglyceride or hydrogenated jojoba oil;
Described skinfeel regulator is at least one in ring five polydimethylsiloxane/cyclohexasiloxane, polydimethylsiloxane or vinyldimethicone/polymethyl siloxane silsesquioxane cross linked polymer;
Described thickening agent is at least one in xanthan gum, hydroxyethyl cellulose or carbomer;
Described wetting agent is at least one in propylene glycol, glycerol or butanediol;
Described preservative is at least one in Bis(hydroxymethyl)imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate, propyl hydroxybenzoate or methyl hydroxybenzoate.
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CN105616522A (en) * 2016-03-02 2016-06-01 广州千百度化妆品有限公司 Traditional Chinese medicine acne cream

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Patent Citations (2)

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US5698199A (en) * 1995-03-10 1997-12-16 Kao Corporation Lipolysis acceleration method
CN102070597A (en) * 2010-12-21 2011-05-25 广西大学 Amide alkaloid and preparation method thereof

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Inventor after: Tang Hesheng

Inventor before: Yang Guangqun

Inventor before: Xie Liping

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Effective date of registration: 20161008

Address after: Jianggao Mountain Industrial Park in Baiyun District of Guangzhou City, Guangdong province 510000 Zhenhua Road No. 52

Patentee after: GUANGZHOU DAAO COSMETICS Co.,Ltd.

Address before: Tianhe District Tong East Road Guangzhou city Guangdong province 510665 B-101 No. 5, room B-118

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Effective date of registration: 20161008

Address after: Tianhe District Tong East Road Guangzhou city Guangdong province 510665 B-101 No. 5, room B-118

Patentee after: GUANGDONG GAOHANG INTELLECTUAL PROPERTY OPERATION Co.,Ltd.

Address before: 510370 Guangdong province Guangzhou City Creek Road in Panlong industrial zone of Liwan District dragon two friends of a 6 storey industrial building

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