CN105250268B - 厄贝沙坦组合物及其在制备治疗急性肾损伤的药物中的应用 - Google Patents
厄贝沙坦组合物及其在制备治疗急性肾损伤的药物中的应用 Download PDFInfo
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- CN105250268B CN105250268B CN201510696494.6A CN201510696494A CN105250268B CN 105250268 B CN105250268 B CN 105250268B CN 201510696494 A CN201510696494 A CN 201510696494A CN 105250268 B CN105250268 B CN 105250268B
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- irbesartan
- kidney injury
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Description
组别 | n | Scr(mmol/L) | BUN(mmol/L) |
假手术组 | 8 | 13.29±2.24★★ | 9.59±1.85★★ |
模型对照组 | 8 | 56.25±6.92 | 37.01±3.07 |
厄贝沙坦组 | 8 | 48.80±8.03★ | 33.20±2.16 |
阿戈美拉汀组 | 8 | 51.66±7.37 | 36.25±2.60 |
厄-阿联用组 | 8 | 28.57±8.04★★▲▲●● | 18.43±2.35★★▲▲●● |
组别 | n | 肾小管损伤评分 |
假手术组 | 8 | 0.182±0.077★★ |
模型对照组 | 8 | 3.538±0.128 |
厄贝沙坦组 | 8 | 3.307±0.095 |
阿戈美拉汀组 | 8 | 3.510±0.112 |
厄-阿联用组 | 8 | 1.831±0.105★★▲▲●● |
Claims (5)
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CN105250268B true CN105250268B (zh) | 2018-08-03 |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101417132A (zh) * | 2007-10-22 | 2009-04-29 | 鲁南制药集团股份有限公司 | 一种含有卡维地洛和血管紧张素ⅱ受体拮抗剂的药物组合物在制备用于治疗肾病的药物中的用途 |
CN102716123A (zh) * | 2012-07-04 | 2012-10-10 | 广东省人民医院 | 一种用于治疗IgA肾病复方制剂 |
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101417132A (zh) * | 2007-10-22 | 2009-04-29 | 鲁南制药集团股份有限公司 | 一种含有卡维地洛和血管紧张素ⅱ受体拮抗剂的药物组合物在制备用于治疗肾病的药物中的用途 |
CN102716123A (zh) * | 2012-07-04 | 2012-10-10 | 广东省人民医院 | 一种用于治疗IgA肾病复方制剂 |
Non-Patent Citations (5)
Title |
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Anti-inflammatory Renoprotective Effect of Clopidogrel and Irbesartan in Chronic Renal Injury;Xiaowen Tu et al.;《J Am Soc Nephrol》;20081231;第19卷;77-83 * |
CyPA与急性肾损伤相关性及作用研究;孟瑚等;《昆明理工大学学报(自然科学版)》;20150430;第40卷(第2期);108-113 * |
Physiological and pharmacological concentrations of melatonin protect against cisplatin-induced acute renal injury;Hakan Parlakpinar et al.;《J. Pineal Res.》;20021231;第33卷;161-166 * |
The Protective Effect of Melatonin and Agomelatin against Cisplatin-Induced Nephrotoxicity and Oxidative Stress in the Rat Kidney;Ismayil YILMAZ et al.;《Latin American Journal of Pharmacy》;20131231;第32卷(第8期);1231-1235 * |
伊贝沙坦对糖尿病大鼠肾氧化应激、NF-κB 活性和ICAM-1 mRNA 表达的影响;曾龙驿等;《中山大学学报( 医学科学版)》;20080731;第29卷(第4期);402-406 * |
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