CN105233175A - Acupoint application for treating liver depression and blood stasis resistance type insomnia - Google Patents

Acupoint application for treating liver depression and blood stasis resistance type insomnia Download PDF

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Publication number
CN105233175A
CN105233175A CN201510771439.9A CN201510771439A CN105233175A CN 105233175 A CN105233175 A CN 105233175A CN 201510771439 A CN201510771439 A CN 201510771439A CN 105233175 A CN105233175 A CN 105233175A
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China
Prior art keywords
radix
point application
blood stasis
salviae miltiorrhizae
paeoniae rubra
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CN201510771439.9A
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Chinese (zh)
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CN105233175B (en
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童蓓丽
章琴
马文欢
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Zhabei District In Shanghai Hospital Of Traditional Chinese Hospital
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Zhabei District In Shanghai Hospital Of Traditional Chinese Hospital
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Abstract

The invention relates to acupoint application for treating liver depression and blood stasis resistance type insomnia. The acupoint application is prepared from radix bupleuri, radix curcumae, calami, radix paeoniae rubra, radix salviae miltiorrhizae and rhizoma chuanxiong. The invention further provides a preparation method of the acupoint application. The acupoint application for treating the liver depression and blood stasis resistance type insomnia has the advantages that an acupoint application medical cake mainly treats the liver depression and blood stasis resistance type insomnia, and the effects of soothing the liver, dispelling melancholy, inducing resuscitation, clearing away the heart fire, calming nerves, promoting blood circulation and removing stasis are achieved. The clinical effect is good, use is convenient, obvious adverse reactions do not exist, and good reputations of majority of patients are achieved.

Description

A kind of point application for the treatment of the insomnia of stagnation of liver-QI blood stasis blocking type
Technical field
The present invention relates to technical field of Chinese medicines, specifically, is a kind of point application for the treatment of the insomnia of stagnation of liver-QI blood stasis blocking type.
Background technology
Insomnia refers to that patient is on not meeting the length of one's sleep or sleep quality and affecting a kind of subjective experience of social function on daytime.It has had a strong impact on human physical and mental health, and accelerate and today of intensified competition in social rhythm, insomnia is a kind of very general phenomenon, has a sleepless night to the life of people, works and bring huge negative effect.
The cause of disease that insomnia occurs is a lot, mainly contains Nervous and Mental Factors, Physical factors, medicine factor, environmental factors etc.Current treatment of insomnia patients doctor trained in Western medicine mainly adopts sedative hypnotic, this kind of medicine has different dependencies and side effect, the disadvantages outweigh the advantages for long-term taking, conventional Benzodiazepines, as estazolam, alprazolam, clonazepam etc., there are hypnosis and angst resistance effect, but can central nervous system dysfunction be caused simultaneously.Chinese patent medicine conventional at present has Tianwang Buxin Dan, Bezoar Sedative Pills, ANSHEN BUXIN WAN, JIAWEI XIAOYAOWAN, ANSHEN BUNAO YE etc.Chinese patent literature CN03158248.6, CN200310107283.1, CN200310107285.0 etc. also disclose the Chinese medicine of a part of Cure for insomnia.But yet there are no report about the point application for the treatment of stagnation of liver-QI blood stasis blocking type insomnia of the present invention.
Summary of the invention
The object of the invention is for deficiency of the prior art, a kind of point application for the treatment of the insomnia of stagnation of liver-QI blood stasis blocking type is provided.
Of the present invention again one object be that a kind of preparation method of point application for the treatment of the insomnia of stagnation of liver-QI blood stasis blocking type is provided.
For achieving the above object, the technical scheme that the present invention takes is: a kind of point application for the treatment of the insomnia of stagnation of liver-QI blood stasis blocking type, described point application is made up of the crude drug of following weight portion: Radix Bupleuri 0.9-1.1 part, Radix Curcumae 0.9-1.1 part, Rhizoma Acori Graminei 0.9-1.1 part, Radix Paeoniae Rubra 1.8-2.2 part, Radix Salviae Miltiorrhizae 1.8-2.2 part, Rhizoma Chuanxiong 0.9-1.1 part.
Described point application is made up of the crude drug of following weight portion: Radix Bupleuri 1 part, Radix Curcumae 1 part, Rhizoma Acori Graminei 1 part, Radix Paeoniae Rubra 2 parts, Radix Salviae Miltiorrhizae 2 parts, Rhizoma Chuanxiong 1 part.
Described point application obtains by the following method: by Radix Bupleuri, Radix Curcumae, Rhizoma Acori Graminei, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong mixing, pulverize, add Borneolum Syntheticum, maltose, water mixes cream processed thoroughly, make point application medicine cake.
The medicine cake size of described point application be 2cm × 2cm, thick for 0.5cm, be heavily 3 grams.
The symptom of stagnation of liver-QI blood stasis blocking type insomnia is: feelings will is smooth, and difficulty is slept at nightfall, vexed gloomy, breast gastral cavity or two side of body distending pain, speaking scarcely,taciturn, lusterless complexion, mottle under the dark and gloomy or socket of the eye of eye socket, purplish tongue dark or ecchymosis, petechia, stringy pulse.
For realizing above-mentioned second object, the technical scheme that the present invention takes is: a kind of preparation method for the treatment of the point application of stagnation of liver-QI blood stasis blocking type insomnia, described preparation method comprises the following steps: by Radix Bupleuri, Radix Curcumae, Rhizoma Acori Graminei, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong mixing, pulverize, add Borneolum Syntheticum, maltose, water mixes cream processed thoroughly, make point application medicine cake.
Described preparation method comprises the following steps: medical material Radix Bupleuri, Radix Curcumae, Rhizoma Acori Graminei, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong are mixed with the ratio of 1:1:1:2:2:1, pulverize, add Borneolum Syntheticum, maltose, water mixes cream processed thoroughly, Borneolum Syntheticum and medical material ratio are 1:10, maltose and water ratio are 5:1, and it is 1:2 that maltose adds water with medical material ratio.
The invention has the advantages that:
1, point application medicine cake of the present invention has effect of dispersing the stagnated live-QI to relieve the stagnation of QI refreshment, clearing away heart-fire for tranquillization, blood circulation promoting and blood stasis dispelling.
2, point application medicine cake of the present invention cures mainly stagnation of liver-QI blood stasis blocking type insomnia, and disease is seen: feelings will is smooth, and difficulty is slept at nightfall, vexed gloomy, breast gastral cavity or two side of body distending pain, speaking scarcely,taciturn, lusterless complexion, mottle under the dark and gloomy or socket of the eye of eye socket.Dark or the ecchymosis (point) of purplish tongue, stringy pulse.
3, point application medicine cake of the present invention clinical practice is after stagnation of liver-QI blood stasis blocking type insomnia patients, obtains good curative effect.Easy to use, there is no obvious adverse reaction, obtain the welcome of patient.
Detailed description of the invention
Below in conjunction with embodiment, detailed description of the invention provided by the invention is elaborated.
A Chinese medicine composition for Cure for insomnia, described Chinese medicine composition is made up of the crude drug of following weight portion: Radix Bupleuri 0.9-1.1 part, Radix Curcumae 0.9-1.1 part, Rhizoma Acori Graminei 0.9-1.1 part, Radix Paeoniae Rubra 1.8-2.2 part, Radix Salviae Miltiorrhizae 1.8-2.2 part, Rhizoma Chuanxiong 0.9-1.1 part.Preferably, Radix Bupleuri 1 part, Radix Curcumae 1 part, Rhizoma Acori Graminei 1 part, Radix Paeoniae Rubra 2 parts, Radix Salviae Miltiorrhizae 2 parts, Rhizoma Chuanxiong 1 part.
Described Chinese medicine composition is mixed, pulverizes, add Borneolum Syntheticum, maltose, water mixes cream processed thoroughly, make point application medicine cake.
Medicine cake also, after rubbing hot Yongquan acupoint with the hands, is spread on bilateral spring, SANYINJIAO acupoint, and fixes with medical proof fabric, throw off after getting up to next day by foot bath before sleeping.
Points for attention: apply ointment or plaster period fasting raw food, seafood, pungent irritable food.To cloth hypersensitivity person, with gauze or bandage fixed drug.After plaster medicine, there is heat, cool, numb, genus normal phenomenon of itching in local, as the place of applying ointment or plaster is burnt or acupuncture sample severe pain, when being difficult to stand, can throw off medicine in advance, if desired hospital admission.
Fang Xie: Radix Bupleuri is monarch, dispersing the stagnated live-QI to relieve the stagnation of QI, Radix Curcumae promoting QI circulation for relieving depression, and clear away heart-fire removing heat from blood, Rhizoma Acori Graminei removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae, and Radix Curcumae is joined Rhizoma Acori Graminei blood stasis dispelling and eliminates phlegm for resuscitation and resolving depression refreshment, and Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, clearing away heart-fire for tranquillization, Radix Curcumae is joined Radix Salviae Miltiorrhizae and shares clearing away heart-fire for tranquillization.Three matches for minister.Radix Paeoniae Rubra clearing away heat and cooling blood, eliminating stasis to stop pain, Rhizoma Chuanxiong circulation of qi promoting, blood circulation promoting and blood stasis dispelling.Two medicines are assistant, match with Radix Salviae Miltiorrhizae and Radix Curcumae, improve the merit of invigorating blood circulation.Borneolum Syntheticum aromatic ventilating siro, transdermal are had one's ideas straightened out, and the skin strengthening medicine absorbs.
Embodiment 1
Radix Bupleuri 1 part, Radix Curcumae 1 part, Rhizoma Acori Graminei 1 part, Radix Paeoniae Rubra 2 parts, Radix Salviae Miltiorrhizae 2 parts, Rhizoma Chuanxiong 1 part
Embodiment 2
Radix Bupleuri 1.1 parts, Radix Curcumae 1 part, Rhizoma Acori Graminei 0.9 part, Radix Paeoniae Rubra 1.9 parts, Radix Salviae Miltiorrhizae 2.2 parts, Rhizoma Chuanxiong 1 part
Embodiment 3
Radix Bupleuri 1 part, Radix Curcumae 1.1 parts, Rhizoma Acori Graminei 1 part, Radix Paeoniae Rubra 1.8 parts, Radix Salviae Miltiorrhizae 2.1 parts, Rhizoma Chuanxiong 1.1 parts
Embodiment 4
Radix Bupleuri 0.9 part, Radix Curcumae 1 part, Rhizoma Acori Graminei 1.1 parts, Radix Paeoniae Rubra 2.1 parts, Radix Salviae Miltiorrhizae 1.8 parts, Rhizoma Chuanxiong 0.9 part
Embodiment 5
Radix Bupleuri 1 part, Radix Curcumae 0.9 part, Rhizoma Acori Graminei 1 part, Radix Paeoniae Rubra 2.2 parts, Radix Salviae Miltiorrhizae 1.9 parts, Rhizoma Chuanxiong 0.9 part
Embodiment 6
Medical material Radix Bupleuri, Radix Curcumae, Rhizoma Acori Graminei, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong are mixed with the ratio of 1:1:1:2:2:1, pulverize, add Borneolum Syntheticum, maltose, water mixes cream processed (Borneolum Syntheticum and medical material ratio 1:10 thoroughly, maltose and water ratio 5:1, with drug ratios 1:2 after maltose adds water and stirs), make size 2cm × 2cm, thick 0.5cm, weigh the medicine cake of 3 grams.
Embodiment 7
Year June in July, 2014 to 2015, carry out Acupoint Application in Treating stagnation of liver-QI blood stasis blocking type insomnia at Shanghai Zhabei Houspital of Traditional Chinese Medicine's " preventive treatment of disease " section, insomnia section and tcm internal medicine.Treat 106 person-times altogether.Per person's treatment time is 2 weeks, applies ointment or plaster to next day and get up before sleeping every night.Issue a questionnaire 106 parts, reclaim application form 89 parts, the response rate reaches 83.96% simultaneously.By gathering the data of recovery, analysis and summary are as follows:
One, physical data
1, Sex distribution is as shown in table 1:
Table 1 Sex distribution
Sex Man Female
Number 37 52
Proportion (%) 41.57 58.42
2, age distribution is as shown in table 2:
Table 2 age distribution
Age (year) Number Proportion (%)
<20 1 1.12
20—29 15 16.86
30—39 19 21.34
40—49 21 23.60
50—59 18 20.22
60—69 10 11.24
≥70 5 5.62
Add up to 89 100
3, diagnostic criteria
Meet Western medicine diagnose standard, the diagnostic criteria of concrete reference " practical internal medicine ", " psychiatry ", " internal disease diagnostic criteria ", ICD-10F51.0 insomnia: a. sleep disorder: comprise difficulty falling asleep, be interrupted to wake up more, dreaminess, seemingly sleep non-ly to sleep, early awakening, wake up after can not fall asleep again, be insomnia even all night; B. above-mentioned sleep disorder at least occurs 3 times weekly, and continues more than 4 weeks; C. occur daytime tired, lassitude, dizzy feeling of fullness in the head, nervous vexed affecting the social activity such as work, study function.
Meet Chinese medical discrimination diagnostic criteria, concrete with reference to " Shanghai City traditional Chinese medical science insomnia characteristic diagnosis and treatment scheme "
Stagnation of liver-QI stasis blocking: feelings will is smooth, difficulty is slept at nightfall, vexed gloomy, breast gastral cavity or two rib distending pain, speaking scarcely,taciturn, lusterless complexion, mottle under the dark and gloomy or socket of the eye of eye socket.Dark or the stasis of blood ecchymosis (point) of purplish tongue, stringy pulse.
Case exclusion standard:
A. above-mentioned diagnostic criteria is not met;
B. the severe primary disease patients such as severe cardiac, brain, lung, kidney or hemopoietic system are associated with;
C. psychotic;
D. trimester of pregnancy or women breast-feeding their children;
E. excessive drinking or downern misuser;
F. uncooperative or therapy discontinued person.
4, interference method:
(1) intervention time: it is a course for the treatment of that per person intervened with 2 weeks
(2) cave is selected in intervention: bilateral spring, SANYINJIAO acupoint
(3) interference method: medicine cake also, after rubbing hot Yongquan acupoint with the hands, is spread on bilateral spring, SANYINJIAO acupoint, and fixes with medical proof fabric, throw off after getting up to next day by foot bath before sleeping.Medicine cake adopts the method for embodiment 6 to obtain.
5, curative effect evaluation
During to change, type SPIEGEL scale score deduction rate calculates.
Clinical recovery: symptom disappears completely or substantially, deduction rate >=80%;
Effective: symptom disappears substantially, deduction rate >=50%;
Effective: symptom is improved or partial symptoms is improved, deduction rate >=30%;
Invalid: symptom is unchanged or increase the weight of, deduction rate < 30%;
Total effective rate is clinical recovery, effective and effective sum.
Two, the effect after intervening is accepted
Efficacy data before and after treatment is as shown in table 3, and SPIEGEL scale score is as shown in table 4.All within normal range, there is not obvious bad toxic and side effects in Chinese medicine of the present invention over the course for the treatment of every safety observations index.
The Comparison of therapeutic of front and back treated by table 3
Curative effect n Recovery from illness Effective Effectively Invalid Effective percentage
Number of cases 89 40 38 10 1 98.9%
Front and back SPIEGEL scale score treated by table 4
Scale Before treatment After treatment
SPIEGEL 32.41±7.32 12.13±6.53
Point application medicine cake of the present invention has dispersing the stagnated live-QI to relieve the stagnation of QI refreshment, clearing away heart-fire for tranquillization, blood circulation promoting and blood stasis dispelling.Clinical practice, after stagnation of liver-QI blood stasis blocking type insomnia patients, obtains good curative effect.Easy to use, there is no obvious adverse reaction, obtain the welcome of patient.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the prerequisite not departing from the inventive method; can also make some improvement and supplement, these improve and supplement and also should be considered as protection scope of the present invention.

Claims (7)

1. treat the point application of stagnation of liver-QI blood stasis blocking type insomnia for one kind, it is characterized in that, described point application is made up of the crude drug of following weight portion: Radix Bupleuri 0.9-1.1 part, Radix Curcumae 0.9-1.1 part, Rhizoma Acori Graminei 0.9-1.1 part, Radix Paeoniae Rubra 1.8-2.2 part, Radix Salviae Miltiorrhizae 1.8-2.2 part, Rhizoma Chuanxiong 0.9-1.1 part.
2. point application according to claim 1, is characterized in that, described point application is made up of the crude drug of following weight portion: Radix Bupleuri 1 part, Radix Curcumae 1 part, Rhizoma Acori Graminei 1 part, Radix Paeoniae Rubra 2 parts, Radix Salviae Miltiorrhizae 2 parts, Rhizoma Chuanxiong 1 part.
3. point application according to claim 1, it is characterized in that, described point application obtains by the following method: by Radix Bupleuri, Radix Curcumae, Rhizoma Acori Graminei, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong mixing, pulverize, add Borneolum Syntheticum, maltose, water mixes cream processed thoroughly, make point application medicine cake.
4. point application according to claim 3, is characterized in that, the medicine cake size of described point application be 2cm × 2cm, thick for 0.5cm, be heavily 3 grams.
5. the preparation method of point application according to claim 1, it is characterized in that, described preparation method comprises the following steps: by Radix Bupleuri, Radix Curcumae, Rhizoma Acori Graminei, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong mixing, pulverize, add Borneolum Syntheticum, maltose, water mixes cream processed thoroughly, make point application medicine cake.
6. the preparation method as requested described in 5, it is characterized in that, described preparation method comprises the following steps: medical material Radix Bupleuri, Radix Curcumae, Rhizoma Acori Graminei, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong are mixed with the ratio of 1:1:1:2:2:1, pulverize, add Borneolum Syntheticum, maltose, water mixes cream processed thoroughly, Borneolum Syntheticum and medical material ratio are 1:10, and maltose and water ratio are 5:1, and it is 1:2 that maltose adds water with medical material ratio.
7. point application according to claim 1, is characterized in that, the symptom of stagnation of liver-QI blood stasis blocking type insomnia is: feelings will is not smooth, and difficulty is slept at nightfall, vexed gloomy, breast gastral cavity or two side of body distending pain, speaking scarcely,taciturn, lusterless complexion, mottle under the dark and gloomy or socket of the eye of eye socket, purplish tongue dark or ecchymosis, petechia, stringy pulse.
CN201510771439.9A 2015-11-12 2015-11-12 A kind of point application for treating the insomnia of liver depression blood stasis blocking type Expired - Fee Related CN105233175B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7366306B1 (en) 2023-05-23 2023-10-20 秋山錠剤株式会社 Method for manufacturing turmeric-containing tablets

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CN104784625A (en) * 2014-01-19 2015-07-22 庄成龙 Traditional Chinese medicine composition for treating insomnia
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7366306B1 (en) 2023-05-23 2023-10-20 秋山錠剤株式会社 Method for manufacturing turmeric-containing tablets

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