CN104189299A - Traditional Chinese medicine preparation for treating central retinitis - Google Patents
Traditional Chinese medicine preparation for treating central retinitis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating central retinitis. The traditional Chinese medicine preparation comprises the following selected raw medicinal materials in weight: 20-30g of rehmannia, 10-20g of mother of pearl, 10-20g of loofah sponge, 10-20g of semen cassiae, 10-20g of medlar, 10-20g of selfheal, 10-20g of rhizoma alismatis, 10-20g of caulis spatholobi, 10-20g of phaseolus calcaratus, 8-15g of leonurus, 8-12g of madder, 8-12g of cassia twig, 8-12g of honeysuckle, 8-12g of peach kernels and 8-12g of fructus forsythiae. The traditional Chinese medicine is good in compatibility of medicines, has the effects of tonifying the liver and kidney, tranquilizing liver and yang, tonifying qi and clearing heat, activating blood and removing stagnation and dredging collaterals and improving eyesight, is used for treating the central retinitis, has the advantages of quick efficiency, short course of treatment, zero side effects, high healing rate and no reappearance, and is worthy of clinical promotion and application.
Description
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation that can therapeutic community's property retinitis.
Background technology
Central serous chorioretinopathy, be clinical in comparatively common a kind of fundus oculi disease.Because of its diseased region blood capillary spasm around foveal region of retina is macular area, therefore claim again central vessel retinitis.Because of Chang Fanfu outbreak, therefore claim again central authorities' property recidivity retinitis.Primary disease master levies as mist and looks, and diminishes or is out of shape, central scotoma etc. depending on thing.Be characterized in macular area edema, foveal reflex weakens or disappears.
Primary disease mostly occurs 20-40 year person between twenty and fifty, and male is high compared with women's sickness rate, and predisposing factors is many because of flu, and work is tired, and psychentonia, does not have enough sleep, and excessively Smoking And Drinking causes retinal pigment epithelium or neuroepithelium infringement.It is generally acknowledged that the small venospasm in optical fundus that nervus vasculairs factor causes is the pathologic basis of this disease morbidity.Die-off because this disease onset shows as vision, again because this disease has repeated relapsing, as effectively treatment not in time, vision meeting permanent lesion, therefore selects optimal treatment method to recover as scheduled vision to patient particularly important.
Summary of the invention
The invention provides a kind of Chinese medicine preparation of therapeutic community's property retinitis, find through clinical practice, medicine of the present invention has instant effect, short treating period, has no side effect, cure rate is high and the advantage of difficult recurrence, clinic promotion and application.
The technical solution adopted in the present invention is: a kind of Chinese medicine preparation of therapeutic community's property retinitis, it is characterized in that, and described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
8-12 grams of Radix Rehmanniae 20-30 gram, Concha Margaritifera 10-20 gram, Retinervus Luffae Fructus 10-20 gram, Semen Cassiae 10-20 gram, Fructus Lycii 10-20 gram, Spica Prunellae 10-20 gram, Rhizoma Alismatis 10-20 gram, Caulis Spatholobi 10-20 gram, 10-20 grams of Semen Phaseolis, Herba Leonuri 8-15 gram, 8-12 gram, Radix Rubiae clothing, Ramulus Cinnamomi 8-12 gram, Flos Lonicerae 8-12 gram, Semen Persicae 8-12 gram, Fructus Forsythiaes.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
20 grams of Radix Rehmanniae, 10 grams of Concha Margaritiferas, 10 grams of Retinervus Luffae Fructuss, 10 grams of Semen Cassiaes, 10 grams of Fructus Lyciis, 10 grams of Spica Prunellaes, 10 grams of Rhizoma Alismatis, 10 grams of Caulis Spatholobis, 10 grams of Semen Phaseolis, 8 grams of Herba Leonuris, 8 grams, Radix Rubiae clothing, 8 grams of Ramulus Cinnamomi, 8 grams of Flos Loniceraes, 8 grams, Semen Persicae, 8 grams of Fructus Forsythiaes.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
25 grams of Radix Rehmanniae, 15 grams of Concha Margaritiferas, 15 grams of Retinervus Luffae Fructuss, 15 grams of Semen Cassiaes, 15 grams of Fructus Lyciis, 15 grams of Spica Prunellaes, 15 grams of Rhizoma Alismatis, 15 grams of Caulis Spatholobis, 15 grams of Semen Phaseolis, 12 grams of Herba Leonuris, 10 grams, Radix Rubiae clothing, 10 grams of Ramulus Cinnamomi, 10 grams of Flos Loniceraes, 10 grams, Semen Persicae, 10 grams of Fructus Forsythiaes.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
30 grams of Radix Rehmanniae, 20 grams of Concha Margaritiferas, 20 grams of Retinervus Luffae Fructuss, 20 grams of Semen Cassiaes, 20 grams of Fructus Lyciis, 20 grams of Spica Prunellaes, 20 grams of Rhizoma Alismatis, 20 grams of Caulis Spatholobis, 20 grams of Semen Phaseolis, 15 grams of Herba Leonuris, 12 grams, Radix Rubiae clothing, 12 grams of Ramulus Cinnamomi, 12 grams of Flos Loniceraes, 12 grams, Semen Persicae, 12 grams of Fructus Forsythiaes.
The instructions of taking of medicine of the present invention is: after the raw material Chinese medicine of above-mentioned weight proportion is mixed, 1 dose of fried rear every day, points 2～3 times oral.Within 1 month, be 1 course for the treatment of, drug withdrawal 2～3 days between the course for the treatment of, then go lower 1 course for the treatment of, can serve on 2～3 courses for the treatment of.
The raw material Chinese medicine of above-mentioned Chinese medicine preparation:
Radix Rehmanniae, sweet in the mouth, hardship, cold in nature; GUIXIN, liver, kidney channel.There is clearing away heat and cooling blood, effect of YIN nourishing and the production of body fluid promoting.
Concha Margaritifera, salty in the mouth, cold in nature; Return liver, heart channel.There is suppressing the hyperactive liver and subsiding YANG, effect of liver heat removing and eyesight improving.
Retinervus Luffae Fructus, sweet in the mouth, cold in nature, return lung, liver, stomach warp.There is dredge the meridian passage, heat-clearing and toxic substances removing, inducing diuresis to remove edema, effect of hemostasis.
Semen Cassiae, sweet in the mouth, hardship, cold nature; Return large intestine channel.There is liver heat removing and eyesight improving, effect of loosening bowel to relieve constipation.
Fructus Lycii, sweet in the mouth, property is flat; Return liver, kidney channel.There is nourishing the liver and kidney, effect of nourishing the liver to improve visual acuity.
Spica Prunellae, acrid in the mouth, hardship, cold in nature; Return liver, gallbladder meridian.There is Liver-Clearing Powder strongly fragrant, effect of suppressing the hyperactive liver and subsiding YANG.
Rhizoma Alismatis, sweet in the mouth, light, cold in nature; Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, the effect of fire of dispelling expels the heat-evil.
Caulis Spatholobi, bitter in the mouth, micro-sweet, warm in nature; Return Liver Channel.There is blood circulation promoting and enriching, effect of relaxing muscles and tendons and activating QI and blood in the collateral.
Semen Phaseoli, sweet in the mouth, acid, property is flat; GUIXIN, small intestine meridian.There is inducing diuresis to remove edema, effect of removing toxic substances and promoting pus discharge.
Herba Leonuri, acrid in the mouth, hardship, cold nature; GUIXIN, liver, urinary bladder channel.There is blood circulation promoting and blood stasis dispelling, effect of inducing diuresis to remove edema.
Radix Rubiae clothing, bitter in the mouth, cold in nature; Return Liver Channel.There is cooling blood for hemostasis, effect of blood circulation promoting and blood stasis dispelling.
Ramulus Cinnamomi, acrid in the mouth, sweet, warm in nature; GUIXIN, lung, urinary bladder channel.There is relieving the exterior syndrome by diaphoresis, effect of warming the meridian for promoting the flow of YANG QI.
Flos Lonicerae, sweet in the mouth, cold in nature; Return lung, the heart, stomach warp.There is heat-clearing and toxic substances removing, effect of wind-heat dissipating.
Semen Persicae, bitter in the mouth, property is flat; GUIXIN, liver, lung, large intestine channel.There is blood circulation promoting and blood stasis dispelling, effect of loosening bowel to relieve constipation.
Fructus Forsythiae, bitter in the mouth, cold nature; Return lung, the heart, gallbladder meridian.There is heat-clearing and toxic substances removing, effect of eliminating carbuncle eliminating stagnation.
The traditional Chinese medical science thinks that central serous chorioretinopathy is many due to seven emotions pent-up, or overwork, Kidney-Yin dark consumption, hyperactivity of YANG due to deficiency of YIN, hyperactivity of deficient fire or by intemperance of taking food, the pathogenic heat stasis of blood is stagnant, and passages through which vital energy circulates is become estranged, retention of damp-heat in the interior, the clear key of upper illiteracy and be trouble, therefore treatment is worked as taking conditioning viscera equilibrium between yin and yang as this, eliminating damp-heat, QI invigorating blood stasis dispelling is mark.In Chinese medicine preparation of the present invention, Radix Rehmanniae, Radix Rubiae clothing can clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling; Concha Margaritifera, Fructus Lycii, Semen Cassiae, Spica Prunellae can nourishing the liver and kidney, liver heat removing and eyesight improving; Rhizoma Alismatis, Ramulus Cinnamomi can relieving the exterior syndrome by diaphoresis, eliminating damp-heat; Caulis Spatholobi, Semen Persicae, Semen Phaseoli, Herba Leonuri can blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, removing toxic substances and promoting subsidence of swelling; Flos Lonicerae, Retinervus Luffae Fructus, Fructus Forsythiae can heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, relaxing muscles and tendons and activating QI and blood in the collateral.All medicine compatibilities are superior, play altogether nourishing liver and kidney, suppressing the hyperactive liver and subsiding YANG, eliminating damp-heat, effect of blood circulation promoting and blood stasis dispelling, gets final product conditioning viscera equilibrium between yin and yang, the body resistance strengthening and constitution consolidating, again can diastole peripheral blood vessel and remove vasospasm, impel eye muscle blood flow to increase, suppress platelet aggregation and antithrombotic and form, fast quick-recovery retinal edema, and then recovery vision, thoroughly cure.
For further investigating the clinical efficacy of medicine of the present invention, we have selected 52 disposition retinitis patients, wherein male 28 examples, female's 24 examples; Age 29-40 year; The course of disease 2 days-3 years.All patients all meet the diagnostic criteria of central serous chorioretinopathy, and get rid of atypical symptom and the diagnosis person of having objection.Patient being divided into treatment group and matched group at random, every group of 26 examples. two groups of cases, at aspect difference not statistically significants (P > 0.05) such as sex, age, the state of an illness, the courses of disease, have comparability.
Therapeutic Method:
Treatment group is taken Chinese medicine preparation of the present invention and is treated, and every day, potion, was decocted in water for oral dose, the 200ml that at every turn takes concoction, point morning, late twice decoction being taken warmly.Matched group troxerutin injection, vitamin C injection intravenous injection, prolonium iodide intramuscular injection, vitamin B1 is oral, and two groups are 30 days courses for the treatment of, and every example is observed two courses for the treatment of, within during treatment every 7 days, does one time vision optical fundus situation record.
Criterion of therapeutical effect:
Cure: clinical symptoms sign disappears, and vision restoration is normal, it is normal that recover on optical fundus.
Effective: clinical symptoms sign is obviously improved, vision is more than front raising 4 row, and obviously improve on optical fundus.
Invalid: clinical symptoms is unchanged, unchanged while morbidity in vision optical fundus.
Efficacy result:
1. Clinical efficacy comparison:
After treatment, treatment group is cured 19 examples, effective 6 examples, invalid 1 example, effective percentage is 96.1%, matched group is cured 8 examples, effective 10 examples, invalid 8 examples, effective percentage is 69.2%, treatment group curative effect is obviously better than matched group, and two groups of comparing differences have statistical significance (P < 0.05).Detailed results is in table 1.
Table 1: two groups of patient's efficacy result synopsis
| Group | Number of cases | Cure n (%) | Effective n (%) | Invalid n (%) | Total effective rate (%) |
| Treatment group | 26 | 19(73.1) | 6(23.1) | 1(3.8) | 96.1 |
| Matched group | 26 | 8(30.8) | 10(38.5) | 8(30.8) | 69.2 |
2. untoward reaction comparison
Add up untoward reaction in two groups of patient treatments, treatment group has no obvious adverse reaction person, and dizzy 3 examples appear in matched group, uncomfortable in chest, heating 6 examples.
Result shows, Chinese medicine preparation of the present invention is used for the treatment of central serous chorioretinopathy, and the advantage that have instant effect, short treating period, have no side effect, cure rate is high is worth further promoting the use of.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation of therapeutic community's property retinitis, choose 20 grams of Radix Rehmanniae, 10 grams of Concha Margaritiferas, 10 grams of Retinervus Luffae Fructuss, 10 grams of Semen Cassiaes, 10 grams of Fructus Lyciis, 10 grams of Spica Prunellaes, 10 grams of Rhizoma Alismatis, 10 grams of Caulis Spatholobis, 10 grams of Semen Phaseolis, 8 grams of Herba Leonuris, 8 grams, Radix Rubiae clothing, 8 grams of Ramulus Cinnamomi, 8 grams of Flos Loniceraes, 8 grams, Semen Persicae, 8 grams of Fructus Forsythiaes.
Embodiment 2: a kind of Chinese medicine preparation of therapeutic community's property retinitis, choose 25 grams of Radix Rehmanniae, 15 grams of Concha Margaritiferas, 15 grams of Retinervus Luffae Fructuss, 15 grams of Semen Cassiaes, 15 grams of Fructus Lyciis, 15 grams of Spica Prunellaes, 15 grams of Rhizoma Alismatis, 15 grams of Caulis Spatholobis, 15 grams of Semen Phaseolis, 12 grams of Herba Leonuris, 10 grams, Radix Rubiae clothing, 10 grams of Ramulus Cinnamomi, 10 grams of Flos Loniceraes, 10 grams, Semen Persicae, 10 grams of Fructus Forsythiaes.
Embodiment 3: a kind of Chinese medicine preparation of therapeutic community's property retinitis, choose 30 grams of Radix Rehmanniae, 20 grams of Concha Margaritiferas, 20 grams of Retinervus Luffae Fructuss, 20 grams of Semen Cassiaes, 20 grams of Fructus Lyciis, 20 grams of Spica Prunellaes, 20 grams of Rhizoma Alismatis, 20 grams of Caulis Spatholobis, 20 grams of Semen Phaseolis, 15 grams of Herba Leonuris, 12 grams, Radix Rubiae clothing, 12 grams of Ramulus Cinnamomi, 12 grams of Flos Loniceraes, 12 grams, Semen Persicae, 12 grams of Fructus Forsythiaes.
Below by concrete case, Chinese medicine preparation curative effect of the present invention is further verified:
Case 1
Wang, man, 35 years old, there is left eye blurred vision without obvious inducement before 3 years in patient, used the medicines such as prednisone, 654-2, vitamin B, vision from disease just 0.6 drop to 0.2, check: the vision right side 1.5, left 0.2, macula area edema, foveal reflex disappears, and has had a strong impact on normal work and life.Take upon somebody's introduction Chinese medicine preparation of the present invention and treat, after 20 doses, patient's readme physical symptom is clearly better, eyesight improving, and further consultation left vision 0.5, macula area edema extinction has yellow-white point to occur simultaneously; Continue to take to 1 course for the treatment of, left vision is increased to 0.7.After 2 courses for the treatment of, left vision 1.2, macula area HUANGBAI(sic) color dot all absorbs, and has pigmentation, and foveal reflex reappears.Follow up a case by regular visits to 1 year without recurrence.
Case 2
Money, female, 32 years old.Patient is the year before without the obvious conscious feverish sensation in the palms and soles of inducement, xerostomia, time have epistaxis, dizziness, headache, ophthalmic bloated, checks left vision 0.7, macula area has the point-like of many filths to ooze out, foveal reflex disappears, and is diagnosed as central serous chorioretinopathy.Upon somebody's introduction, take medicine of the present invention and treat, after 1 course for the treatment of, patient's muscae genetic vision significantly brightens, and checks left vision 0.9, and macular edema disappears substantially; Continue to take after 10 doses of after treatments, left vision is increased to 1.2, and macular edema disappears completely, and foveal reflex reappears.Follow up a case by regular visits to half a year without recurrence.
Case 3
Grandson, man, 43 years old.Before patient half a year, occurred without obvious inducement that right eye was fuzzy suddenly, loose stool every day 3 times, poor appetite, white and greasy fur, checks right vision 0.5, macula area foveal reflex is strong, has yellow-white to ooze out a calmness, is diagnosed as central serous chorioretinopathy.Upon somebody's introduction, take medicine of the present invention and treat, after 15 doses, patient's muscae genetic vision significantly brightens, and checks right vision 1.0, and yellow-white oozes out a little large portion absorption; Continue to take 1 curative effect, vision restoration to 1.2, yellow-white oozes out a little and absorbs completely, and foveal reflex reappears.Follow up a case by regular visits to and within three months, have no recurrence.
Claims (4)
1. a Chinese medicine preparation for therapeutic community's property retinitis, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
8-12 grams of Radix Rehmanniae 20-30 gram, Concha Margaritifera 10-20 gram, Retinervus Luffae Fructus 10-20 gram, Semen Cassiae 10-20 gram, Fructus Lycii 10-20 gram, Spica Prunellae 10-20 gram, Rhizoma Alismatis 10-20 gram, Caulis Spatholobi 10-20 gram, 10-20 grams of Semen Phaseolis, Herba Leonuri 8-15 gram, 8-12 gram, Radix Rubiae clothing, Ramulus Cinnamomi 8-12 gram, Flos Lonicerae 8-12 gram, Semen Persicae 8-12 gram, Fructus Forsythiaes.
2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the raw material of following weight portion:
20 grams of Radix Rehmanniae, 10 grams of Concha Margaritiferas, 10 grams of Retinervus Luffae Fructuss, 10 grams of Semen Cassiaes, 10 grams of Fructus Lyciis, 10 grams of Spica Prunellaes, 10 grams of Rhizoma Alismatis, 10 grams of Caulis Spatholobis, 10 grams of Semen Phaseolis, 8 grams of Herba Leonuris, 8 grams, Radix Rubiae clothing, 8 grams of Ramulus Cinnamomi, 8 grams of Flos Loniceraes, 8 grams, Semen Persicae, 8 grams of Fructus Forsythiaes.
3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the raw material of following weight portion:
25 grams of Radix Rehmanniae, 15 grams of Concha Margaritiferas, 15 grams of Retinervus Luffae Fructuss, 15 grams of Semen Cassiaes, 15 grams of Fructus Lyciis, 15 grams of Spica Prunellaes, 15 grams of Rhizoma Alismatis, 15 grams of Caulis Spatholobis, 15 grams of Semen Phaseolis, 12 grams of Herba Leonuris, 10 grams, Radix Rubiae clothing, 10 grams of Ramulus Cinnamomi, 10 grams of Flos Loniceraes, 10 grams, Semen Persicae, 10 grams of Fructus Forsythiaes.
4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the raw material of following weight portion:
30 grams of Radix Rehmanniae, 20 grams of Concha Margaritiferas, 20 grams of Retinervus Luffae Fructuss, 20 grams of Semen Cassiaes, 20 grams of Fructus Lyciis, 20 grams of Spica Prunellaes, 20 grams of Rhizoma Alismatis, 20 grams of Caulis Spatholobis, 20 grams of Semen Phaseolis, 15 grams of Herba Leonuris, 12 grams, Radix Rubiae clothing, 12 grams of Ramulus Cinnamomi, 12 grams of Flos Loniceraes, 12 grams, Semen Persicae, 12 grams of Fructus Forsythiaes.
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Cited By (2)
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| CN105194566A (en) * | 2015-10-28 | 2015-12-30 | 严中明 | Traditional Chinese medicine composition for treatment of swelling and pain of eye caused by liver and gall heat excess |
| KR20190133978A (en) * | 2018-05-24 | 2019-12-04 | 종근당건강 주식회사 | Pharmaceutical composition for preventing or treating of macular degeneration comprising Prunella vulgaris var. lilacina extract as an active ingredient |
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| CN104043011A (en) * | 2014-06-19 | 2014-09-17 | 王春水 | Traditional Chinese medicine composition for treating central retinitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105194566A (en) * | 2015-10-28 | 2015-12-30 | 严中明 | Traditional Chinese medicine composition for treatment of swelling and pain of eye caused by liver and gall heat excess |
| KR20190133978A (en) * | 2018-05-24 | 2019-12-04 | 종근당건강 주식회사 | Pharmaceutical composition for preventing or treating of macular degeneration comprising Prunella vulgaris var. lilacina extract as an active ingredient |
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| CN104189299B (en) | 2018-09-21 |
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