CN105233029A

CN105233029A - Chinese and western medicine compound preparation for premenstrual syndrome

Info

Publication number: CN105233029A
Application number: CN201510677440.5A
Authority: CN
Inventors: 岳永磊; 王羲笛; 赵爱娥
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-10-16
Filing date: 2015-10-16
Publication date: 2016-01-13

Abstract

The invention discloses a Chinese and western medicine compound preparation for premenstrual syndrome. The Chinese and western medicine compound preparation consists of traditional Chinese medicine components and western medicine components, wherein the traditional Chinese medicine components are mainly prepared by extracting the following drug substances: bon colysis, daphniphyllum root, stem and leaf of Chinese pulsatilla, yellowflower toadlily herb, inflorescence of Miscanthus sinensis Anderss., herb of dewberryleaf cinquefoil, Aucuba chinensis Benth.subsp.omeienisis(Fang)Fang et Solng Au-cuba chinensis Benth., radix cycleae hypoglaucae, fructus livistonae, lapis micae aureum, herb or root of Galium verum L., herb of Viola formosana Hayata, herb of Indian pentanema, flos magnoliae officinalis, halite, root of common lantana, corymb polycarpaea herb, banana root, Japanese snakegourd root, common rush herb, cladonia fallax abbayes and root of lineate supplejack; and the western components are as follows: fluoxertine hydrochloride, N-acetylcysteine, naproxen sodium, glutamic acid, citrulline, sodium citrate, ferrous glycine chelate, folic acid and a nutrition additive. The Chinese and western medicine compound preparation has the effects of activating blood circulation to dissipate blood stasis, discharging fire and eliminating dampness, relaxing bowel, easing mental anxiety and regulating the nervous system, can relax heart and cerebral vessels, reduce pressure, overcome gloomy mood, prevent depression and maintain the immunity, realizes favorable coordination of the traditional Chinese medicines and western medicines, can radically treat premenstrual syndrome and has a remarkable curative effect.

Description

A kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis

Technical field

The present invention relates to medical art, specifically relate to a kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis.

Background technology

Menstrual psychosis menstruation psychosis be exactly women often before menstrual onset 2 weeks unhappy, anxiety is irritated, is called " premenstrual tension syndrome ".Separately there are some women's situations even more serious, Mental Subnormality, even occur vain hope hallucination, but once menstrual onset, the state of an illness suddenly recovered from an illness; Next month is so multiple again.

The feature of this disease is: in premenstrual 2 weeks of the moon (onset of ovulation or luteal phase) sudden onset, alleviate rapidly at menstrual onset or when clean, the state of an illness is not limited to anxious state of mind, psychotic symptoms can be there is, particularly hallucination, obvious incoordination locomotor stimulatory, minority is motion suppression; With the conduct disorder of mild cognitive obstacle; The hallucination of segment, vain hope and language disorder; Obvious elation or low.Each duration of seizure is of short duration,

Being no more than 2 weeks, alleviating period, there is sufficient insight, an urgent demand treatment and prevention of recurrence, but to next cycle natural occurrence again.

Once thought in the past, problem is the deficiency of gonadal hormone, by the method for supplementary Progesterone, can adjust lutein and estrogenic ratio in body, thus cure diseases.By putting into practice for many years, found that problem not at this level of gonadal hormone, and in more high-rise mesencephalic centre.But general antipsychotic drug or electric shock treatment all do not have obvious curative effects, sex hormone drug has some improvement effect, but still cannot effect a radical cure.Therefore, need to develop a kind of medicine that effectively can effect a radical cure menstrual psychosis menstruation psychosis, to make up the blank of prior art.

Summary of the invention

The technical problem that the present invention solves is, provides a kind of evident in efficacy, does not recur, can effect a radical cure the Chinese medicine and western medicine compound preparation of menstrual psychosis menstruation psychosis more.

Technical scheme of the present invention is:

A kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 80 ~ 180 parts of Colysis bonii Ching., 30 ~ 100 parts of Radix Daphniphylli calycinis, 150 ~ 300 parts of Caulis et Folium Pulsatillaes, 100 ~ 300 parts of Herba Tricyrtis Pilosaes, 120 ~ 200 portions of awns, 90 ~ 150 parts of Herba Potentillae Fragarioidiss, 100 ~ 150 parts of Folium Aucubae chinensis roots, 100 ~ 200 parts of Radix Ilicis Asprellae rattans, 20 ~ 60 parts of Chinese fanpalm seeds, 30 ~ 90 parts of Lapis Micae Aureuses, 50 ~ 150 parts of Herba galii veris, 70 ~ 150 parts of Crusta Penaeus seu Panulirus money, 40 ~ 100 parts of Herba Pentanematis Indicis, 30 ~ 60 parts of Flos Magnoliae Officinalises, 60 ~ 150 parts of halites, 100 ~ 200 parts of Radix Lantanae Camaraevs, 150 ~ 250 parts of Herba Polycarpaeae Corymbosaes, 40 ~ 100 parts of Banana Roots, 80 ~ 150 parts of Radix Trichosanthis Cucumeroidiss, 50 ~ 150 parts of Medulla Juncis, 30 ~ 100 parts of Cladonia fallax Abbayess, 20 ~ 50 parts of Radix berchemiae lineataes, described western medicine composition comprises following component: 3 ~ 7 parts of fluoxetine Hydrochlorides, 2 ~ 8 parts of N-acetylcysteins, 1 ~ 6 part of naproxen sodium, 5 ~ 10 parts of glutamic acid, 5 ~ 15 parts of citrulline, 2.5 ~ 5.5 parts of sodium citrate, 0.8 ~ 2.4 part of iron supplementary, 0.5 ~ 1.5 part of folic acid, 1.2 ~ 2.0 parts of nourishing additive agents, further, for strengthening its curative effect, this Chinese medicine and western medicine compound preparation being used for menstrual psychosis menstruation psychosis can also add 60 ~ 180 parts of Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendles, 100 ~ 200 Fen Herba Cirsii Linearis, 100 ~ 150 parts of Macaranga tanarius, 30 ~ 90 parts of Pericarpium Citri grandiss as Effective Component of Chinese Medicine.

Further, described a kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, is made up of Chinese medicine ingredients and western medicine composition, and by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 80 ~ 180 parts of Colysis bonii Ching., 30 ~ 100 parts of Radix Daphniphylli calycinis, 150 ~ 300 parts of Caulis et Folium Pulsatillaes, 100 ~ 300 parts of Herba Tricyrtis Pilosaes, 120 ~ 200 portions of awns, 90 ~ 150 parts of Herba Potentillae Fragarioidiss, 100 ~ 150 parts of Folium Aucubae chinensis roots, 100 ~ 200 parts of Radix Ilicis Asprellae rattans, 20 ~ 60 parts of Chinese fanpalm seeds, 30 ~ 90 parts of Lapis Micae Aureuses, 50 ~ 150 parts of Herba galii veris, 70 ~ 150 parts of Crusta Penaeus seu Panulirus money, 40 ~ 100 parts of Herba Pentanematis Indicis, 30 ~ 60 parts of Flos Magnoliae Officinalises, 60 ~ 150 parts of halites, 100 ~ 200 parts of Radix Lantanae Camaraevs, 150 ~ 250 parts of Herba Polycarpaeae Corymbosaes, 40 ~ 100 parts of Banana Roots, 80 ~ 150 parts of Radix Trichosanthis Cucumeroidiss, 50 ~ 150 parts of Medulla Juncis, 30 ~ 100 parts of Cladonia fallax Abbayess, 20 ~ 50 parts of Radix berchemiae lineataes, 40 ~ 100 parts of Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) roots, 30 ~ 90 parts of Rhizoma soulieae vaginataes, 50 ~ 100 parts of Herba Hippuridis Vulgaris, 60 ~ 180 parts of Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendles, 100 ~ 200 Fen Herba Cirsii Linearis, 100 ~ 150 parts of Macaranga tanarius, 30 ~ 90 parts of Pericarpium Citri grandiss, described western medicine composition comprises following component: 3 ~ 7 parts of fluoxetine Hydrochlorides, 2 ~ 8 parts of N-acetylcysteins, 1 ~ 6 part of naproxen sodium, 5 ~ 10 parts of glutamic acid, 5 ~ 15 parts of citrulline, 2.5 ~ 5.5 parts of sodium citrate, 0.8 ~ 2.4 part of iron supplementary, 0.5 ~ 1.5 part of folic acid, 1.2 ~ 2.0 parts of nourishing additive agents.

Further, described iron supplementary is ferrum glycinate, and iron supplement can improve feminine menstrual anemia.

Further, described nourishing additive agent is vitamin B6, vitamin B12, beta-carotene, part by weight between three is (2 ~ 3): (1 ~ 3): (2 ~ 5), appropriate vitimin supplement, can promote to increase energy, enhancing immunity with citrulline combined effect.

Further, the extraction preparation method of described Chinese medicine ingredients is:

(1) get the Colysis bonii Ching. of formula ratio, Radix Daphniphylli calycini, Caulis et Folium Pulsatillae, Herba Tricyrtis Pilosae, awns spent, Herba Potentillae Fragarioidis, Folium Aucubae chinensis root, Radix Ilicis Asprellae rattan, Chinese fanpalm seed, Lapis Micae Aureus, Herba galii veri, Crusta Penaeus seu Panulirus money, Herba Pentanematis Indici, Flos Magnoliae Officinalis, halite, Radix Lantanae Camaraev, Herba Polycarpaeae Corymbosae, Banana Root, Radix Trichosanthis Cucumeroidis, Medulla Junci, Cladonia fallax Abbayes, Radix berchemiae lineatae, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, Rhizoma soulieae vaginatae, Herba Hippuridis Vulgaris, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle, Herba Cirsii Linearis, Macaranga tanarius, Pericarpium Citri grandis, clean up with the tap water of flowing, pull out, dry;

(2) pulverize with pulverizer, cross 40 ~ 100 mesh sieves, obtain mixed-powder, with the water soaking 5 ~ 10h relative to mixed-powder weight 10 ~ 12 times;

(3) mixed-powder drops into multi-function extractor together with the water soaked, heating decocts, decocting time is 2 ~ 3h, filter, gained filtering residue add again relative to mixed-powder weight 5 ~ 8 times water by medical material decoct 1 ~ 2h, filter, gained filtering residue add again relative to mixed-powder weight 2 ~ 3 times water by medical material decoct 0.5 ~ 1.5h, filter, above-mentioned three times are filtered the medicinal liquid mixing obtained, be concentrated into 55 ~ 60%.

(4) in step (3) extraction concentrated solution adds, the ethanol that concentration is 75 ~ 85% is entered, concentrated solution alcohol content is made to reach 65 ~ 70%, after having precipitate to occur, continue to leave standstill 24 ~ 30h, after thing to be precipitated fully precipitates, extract supernatant out, supernatant reclaims ethanol extremely without alcohol taste, reconcentration becomes fluid extract, and spraying dry makes extract powder, namely obtains described Chinese medicine ingredients.

Further, described a kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, preparation method is:

(5) described Chinese medicine ingredients is mixed in dispensing canister with fluoxetine Hydrochloride, N-acetylcystein, naproxen sodium, glutamic acid, citrulline, 2 sodium citrate, ferrum glycinate, folic acid, nourishing additive agent, add pharmaceutical carrier 120 ~ 300 parts, dispersant 48 ~ 70 parts, antiseptic 0.1 ~ 0.3 part, obtain semi-finished product, then make tablet, hard capsule, soft capsule or other pharmaceutically acceptable dosage forms.

Further, described pharmaceutically suitable carrier is any one or two or more mixture in following composition: s6, carboxymethyl starch sodium, sodium lauryl sulphate, can help medicine molding, and reduce drug degradation and loss, reduce side effect, improve bioavailability.

Further, described dispersant is polyethylene glycols, can improve medicine dispersive property.

Further, described antiseptic is parabens or potassium sorbate, can extend the quality guarantee period of medicament phase.

Medical material present Research involved in the present invention is as follows:

Colysis bonii Ching.: [nature and flavor] micro-hardship; Puckery; Cool.[return through] enters liver, kidney, bladder three warp.[function cures mainly] blood circulation promoting and blood stasis dispelling; Clearing away heat and promoting diuresis.Main traumatic injury; Little example drenches the puckery pain of drop.

Radix Daphniphylli calycini: [nature and flavor] acrid in the mouth; Bitter; Cool in nature; Mild toxicity.[return through] lung; Large intestine channel.[function cures mainly] heat-clearing and toxic substances removing; Blood circulation promoting and blood stasis dispelling; Reducing swelling and alleviating pain.Main fever caused by exogenous pathogens; Cough; Laryngopharynx swelling and pain; The lower mass in the abdomen of the side of body; Rheumatic ostalgia; Traumatic injury.

Caulis et Folium Pulsatillae: [nature and flavor] bitter in the mouth; Cold in nature.[return through] returns liver; Stomach warp.[function cures mainly] eliminating fire and detoxication; Pain relieving; Inducing diuresis to remove edema.Cure mainly acute toothache; Extremities joint pain; Tinea alba; Edema.

Herba Tricyrtis Pilosae: [nature and flavor] are sweet, light is flat.[function cures mainly] calms the nerves relieving restlessness, promoting blood circulation and detumescence.Thirsty, dysphoria, traumatic injury.

Awns: [nature and flavor] are sweet; Flat.[function cures mainly] promoting blood circulation to restore menstrual flow.Main menoxenia; Amenorrhea; Post partum longtime lochia; Hemiplegia.

Herba Potentillae Fragarioidis: [nature and flavor] are sweet, temperature.[function cures mainly] blood circulation promoting and blood stasis dispelling, replenishing YIN and removing heat.Gas in benefit, nourishing YIN is empty, hemostasis.

Folium Aucubae chinensis root: [nature and flavor] bitter in the mouth; Pungent; Warm in nature.[function cures mainly] expelling wind and removing dampness; Blood circulation promoting and blood stasis dispelling.Main air pain of dampness syndrome; Traumatic injury congestive edema.

Radix Ilicis Asprellae rattan: [nature and flavor] are bitter; Cold.[return through] lung; Large intestine; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Wind-expelling pain-stopping; Relieving stranguria by diuresis.Main anemopyretic cold; Cough; Laryngopharynx swelling and pain; Diphtheria; Acute toothache; Intestinal is scorching; Dysentery; Urinary tract infection and lithangiuria; Rheumatalgia; Sore swollen toxin; Venom.

Chinese fanpalm seed: [nature and flavor] sweet in the mouth; Bitter; Property is put down; Mild toxicity.[function cures mainly] blood circulation promoting and blood stasis dispelling; Hard masses softening and resolving.Main chronic hepatitis; Lump in the abdomen.

Lapis Micae Aureus: [nature and flavor] are sweet, salty is flat.[return through] returns lung, the heart, Liver Channel.[function cures mainly] pendant expectorant therapeutic method to keep the adverse QI flowing downwards, checking hyperfunction of the liver for relieving convulsion.Cementing for pertinacious phlegm, cough with dyspnea dyspnea with rapid respiration, epilepsy is gone mad, irritated uncomfortable in chest, convulsion with spasms.

Herba galii veri: [nature and flavor] are bitter, sweet, temperature.[function cures mainly] detoxifies, and dampness removing is antipruritic.For acute urticaria, paddy-field dermatitis, phlebitis, carbuncle furuncle furuncle, women's vim and vigour pain.

Crusta Penaeus seu Panulirus money: [function cures mainly] spleen benefiting and stimulating the appetite; Dispelling wind stopping cough; Promoting blood circulation to restore menstrual flow.It is depressed that main children's eats drink; Flu; Cough; Dysmenorrhea; Redly collapse leucorrhea; Stomachache dysentery; Rheumatism.

Herba Pentanematis Indici: [nature and flavor] " Red River Chinese herbal medicine ": " light, cool." [function cures mainly] " Red River Chinese herbal medicine ": " heat-clearing and toxic substances removing, relieving stranguria by diuresis."。

Flos Magnoliae Officinalis: [nature and flavor] are bitter, tepor.[return through] returns spleen, stomach warp.[function cures mainly] the chest stuffiness relieving reason diaphragm, sending down the abnormal ascending QI is regulated the flow of vital energy, removing dampness.Control septum pectorale feeling of distension and oppression, poor appetite.

Halite: [nature and flavor] are salty, cold.[return through] heart; Kidney; Liver; Lung; Urinary bladder channel.[function cures mainly] purges heat; Removing heat from blood; Improving eyesight; Moisturize.Main hematuria; Spit blood; Radula is hemorrhage; Conjunctival congestion and swelling pain; The rotten string of wind-eye; Toothache; Constipation.

Radix Lantanae Camaraev: [nature and flavor] Guangzhou army " conventional Chinese herbal medicine handbook ": " sweetness and bitterness, cold." [function cures mainly] invigorates blood circulation, and dispels the wind, dampness removing, heat clearing away.Dispelling the wind and dampness pathogens arthralgia pain, beriberi, flu, mumps, traumatic injury.

Herba Polycarpaeae Corymbosae: [nature and flavor] " Quanzhou book on Chinese herbal medicine ": " sweet, flat, nontoxic." [return through] " Quanzhou book on Chinese herbal medicine ": " enters the heart, liver, lung, all warps of stomach." [function cures mainly] be " Quanzhou book on Chinese herbal medicine " the 1.: " poison that relieves inflammation or internal heat is hot and suffocating, opens breast profit diaphragm.Control middle stagnation of QI knot, treating stranguria diuresis, lactogenesis, detumescence poison and all poisonous insect snakebites." 2. Guangzhou air force " conventional Chinese herbal medicine handbook ": " heat-clearing and toxic substances removing, dehumidifying diuresis.Control acute bacillary dysentery, enteritis, case of a physically strong patient running a high fever ascites, dyspepsia."

Banana Root: [nature and flavor] sweet in the mouth; Cold in nature.[return through] stomach warp.[function cures mainly] clearing away heat and cooling blood; Removing toxic substances.Main calentura excessive thirst; Stranguria with blood; Carbuncle.

Radix Trichosanthis Cucumeroidis: [nature and flavor] are bitter, cold.Slightly poisonous.[function cures mainly] heat-clearing and toxic substances removing, inducing diuresis to remove edema, eliminating stasis to stop pain.Purge heat, promote the production of body fluid, removing blood stasis, repercussive." Japan hanako materia medica ": " wine jaundice, high fever is vexed vexed, evacuation of pus, hot labor for promoting blood circulation, the capable hot disease in main sky.Control and flutter damage, repercussive blood.

Medulla Junci: [nature and flavor] are bitter, cool.[function cures mainly] be " herbal classic " 1.: " main trusted subordinate's pathogen, dysuria, stranguria with urinary obstruction, rheumatism.It is not enough that " 2. " not Lu ": " mends interior-deficiency, feeling of fullness, and body, without moist, is perspired, except heat and pain in the penis.Main treatment ascarid and indigestion again." 3. Wang Lian bodyguard " book of gathering medicinal herbs ": " falls apart wind-fire, and Dali is damp and hot." 4. " Zhejiang traditional herbal medicine ": " relieving stranguria by diuresis, heat clearing and tranquillizing."

Cladonia fallax Abbayes: [nature and flavor] are bitter is flat.[function cures mainly] is calm, pain relieving, convergence.For neurasthenia, epilepsy, schizophrenia, the vertigo, traumatic injury; Burn and scald is controlled in external.

Radix berchemiae lineatae: [nature and flavor] micro-hardship, puckery is flat.[function cures mainly] removing stasis to stop bleeding, antitussive pain relieving.For hemoptysis of pulmonary tuberculosis, taste-blindness rate is hemorrhage, schizophrenia, traumatic injury, rheumatic ostalgia, furuncle furuncle and phyma, deradenoncus, painful and swollen testis, controls manic type and inhibitable type psychosis.

Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root: [nature and flavor] are sweet; Flat.[return through] stomach; Heart channel.[function cures mainly] dispelling wind stomach function regulating; Mind tranquilizing and the heart calming.Main diseases caused by exogenous pathogenic factor ailment said due to cold or exposure; Headache; Nausea and vomiting; Cardiopalmus; Dysphoria.

Rhizoma soulieae vaginatae: [nature and flavor] are bitter; Cool.[return through] heart; Lung; Stomach; Large intestine channel.[function cures mainly] " Shaanxi Chinese herbal medicine ": " pathogenic fire purging dampness, clear away heart-fire relieving restlessness, anti-inflammation, stomach invigorating.Control pharyngitis, conjunctivitis, stomatitis, osteopyrexia and fever, nervous cardiopalmus, controls calentura agitation; Dysphoria, bacillary dysentery, enteritis, carbuncle pyogenic infections from tumour or sore."

Herba Hippuridis Vulgaris: [nature and flavor] are bitter, micro-sweet, cool.[function cures mainly] clearing away heat and cooling blood, nutrient solution of promoting the production of body fluid.Antitussive, soothing liver-QI, cooling blood for hemostasis, YIN nourishing and the production of body fluid promoting, deep steaming.Cure mainly high hot excessive thirst, tuberculosis is coughed, the hot hectic fever due to YIN-deficiency of consumptive disease, pain in the hypochondrium, gastroenteritis etc.

Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle: [nature and flavor] are bitter; Cold; Light; Sweet.[return through] heart; Liver Channel.[function cures mainly] clears away heart-fire relieving restlessness; Diuresis; Removing toxic substances.Main calentura excessive thirst; Oliguria with reddish urine; Burn and scald

Herba Cirsii Linearis: [nature and flavor] bitter in the mouth; Cold nature.[function cures mainly] " Hunan medicine will ": broken stagnated blood, tissue regeneration promoting blood, relieving heat toxin, sharp chest and diaphragm, except unhappy, tonifying deficiency.

Macaranga tanarius: [function cures mainly] relieving constipation by purgation; Anticancer.Main constipation; Malignant tumor; Nervous system and cardiovascular system diseases.

Pericarpium Citri grandis: [nature and flavor] are pungent; Bitter; Sweet; Temperature.[return through] spleen; Kidney; Urinary bladder channel.[function cures mainly] alleviating distention in middle-JIAO is regulated the flow of vital energy; Help digestion; Reduce phlegm; Relieving cough and asthma.Main stagnation of QI breast is vexed; Coldness and pain in the epigastrium; Food stagnation; Dysentery; Cough with asthma; Hernia, help digestion fast diaphragm, and the gas of loose resentfulness, reduces phlegm.

Citrulline: improve function of immune system, balance normal blood sugar level, absorbs harmful free radical containing abundant antioxidant, the blood vessel of people can be made to obtain lax, reduces pressure and overcome dejected emotion.Appropriate citrulline and various vitamin can promote to increase energy, and maintain immune system, and citrulline helps physical recovery fatigue and pressure, can also maintain health ph balancing.

Sodium citrate: for correcting the acidity of blood, body fluid and urine, anticoagulant, reduce phlegm, diuresis.

The invention has the beneficial effects as follows, selected Chinese crude drug have blood circulation promoting and blood stasis dispelling, pathogenic fire purging dampness, clearing away heat and cooling blood, dampness removing is treating stranguria, dispelling wind stomach function regulating, relieving constipation by purgation, the relieving restlessness that clears away heart-fire, tranquillizing and allaying excitement, nervous system regulation effect, with Western medicine combined effect, can be relaxed cardiovascular and cerebrovascular vessel, reduce pressure, overcome dejected emotion, anti-depression, promote to increase energy, and maintain immunity, do not interact between Chinese medicine and western medicine, and no-float, complement each other, can menstrual psychosis menstruation psychosis be effected a radical cure, evident in efficacy, do not recur more.

Detailed description of the invention

Embodiment 1:

A kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 80 parts of Colysis bonii Ching., 30 parts of Radix Daphniphylli calycinis, 150 parts of Caulis et Folium Pulsatillaes, 100 parts of Herba Tricyrtis Pilosaes, 120 portions of awns, 90 parts of Herba Potentillae Fragarioidiss, 100 parts of Folium Aucubae chinensis roots, 100 parts of Radix Ilicis Asprellae rattans, 20 parts of Chinese fanpalm seeds, 30 parts of Lapis Micae Aureuses, 50 parts of Herba galii veris, 70 parts of Crusta Penaeus seu Panulirus money, 40 parts of Herba Pentanematis Indicis, 30 parts of Flos Magnoliae Officinalises, 60 parts of halites, 100 parts of Radix Lantanae Camaraevs, 150 parts of Herba Polycarpaeae Corymbosaes, 40 parts of Banana Roots, 80 parts of Radix Trichosanthis Cucumeroidiss, 50 parts of Medulla Juncis, 30 parts of Cladonia fallax Abbayess, 20 parts of Radix berchemiae lineataes, described western medicine composition comprises following component: 3 parts of fluoxetine Hydrochlorides, 2 parts of N-acetylcysteins, 1 part of naproxen sodium, 5 parts of glutamic acid, 5 parts of citrulline, 2.5 parts of sodium citrate, 0.8 part of iron supplementary, 0.5 part of folic acid, 1.2 parts of nourishing additive agents.

Wherein, described iron supplementary is ferrum glycinate, and iron supplement can improve feminine menstrual anemia.Described nourishing additive agent is vitamin B6, vitamin B12, beta-carotene, and the part by weight between three is 2:1:2, appropriate vitimin supplement, can promote to increase energy, enhancing immunity with citrulline combined effect.

The extraction preparation method of described Chinese medicine ingredients is:

(1) get the Colysis bonii Ching. of formula ratio, Radix Daphniphylli calycini, Caulis et Folium Pulsatillae, Herba Tricyrtis Pilosae, awns spent, Herba Potentillae Fragarioidis, Folium Aucubae chinensis root, Radix Ilicis Asprellae rattan, Chinese fanpalm seed, Lapis Micae Aureus, Herba galii veri, Crusta Penaeus seu Panulirus money, Herba Pentanematis Indici, Flos Magnoliae Officinalis, halite, Radix Lantanae Camaraev, Herba Polycarpaeae Corymbosae, Banana Root, Radix Trichosanthis Cucumeroidis, Medulla Junci, Cladonia fallax Abbayes, Radix berchemiae lineatae, clean up with the tap water of flowing, pull out, dry;

(2) pulverize with pulverizer, cross 40 mesh sieves, obtain mixed-powder, with the water soaking 5h relative to mixed-powder weight 10 times;

(3) mixed-powder drops into multi-function extractor together with the water soaked, heating decocts, decocting time is 2h, filter, gained filtering residue adds, relative to the water of mixed-powder weight 5 times, medical material is decocted 1h, filters, gained filtering residue adds, relative to the water of mixed-powder weight 2 times, medical material is decocted 0.5h, filter, above-mentioned three times are filtered the medicinal liquid mixing obtained, be concentrated into 55%.

(4) in step (3) extraction concentrated solution adds, the ethanol that concentration is 75% is entered, concentrated solution alcohol content is made to reach 65%, after having precipitate to occur, continue to leave standstill 24h, after thing to be precipitated fully precipitates, extract supernatant out, supernatant reclaims ethanol extremely without alcohol taste, reconcentration becomes fluid extract, and spraying dry makes extract powder, namely obtains described Chinese medicine ingredients.

This is used for the Chinese medicine and western medicine compound preparation of menstrual psychosis menstruation psychosis, and preparation method is:

(5) described Chinese medicine ingredients is mixed in dispensing canister with fluoxetine Hydrochloride, N-acetylcystein, naproxen sodium, glutamic acid, citrulline, 2 sodium citrate, ferrum glycinate, folic acid, nourishing additive agent, add pharmaceutical carrier 120 parts, dispersant 48 parts, antiseptic 0.1 part, obtain semi-finished product, then make tablet.Described pharmaceutically suitable carrier is s6, can help medicine molding, and reduces drug degradation and loss, reduces side effect, improves bioavailability.Described dispersant is polyethylene glycols, can improve medicine dispersive property.Described antiseptic is parabens, can extend the quality guarantee period of medicament phase.

Embodiment 2:

A kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 130 parts of Colysis bonii Ching., 65 parts of Radix Daphniphylli calycinis, 225 parts of Caulis et Folium Pulsatillaes, 200 parts of Herba Tricyrtis Pilosaes, 160 portions of awns, 120 parts of Herba Potentillae Fragarioidiss, 125 parts of Folium Aucubae chinensis roots, 150 parts of Radix Ilicis Asprellae rattans, 40 parts of Chinese fanpalm seeds, 60 parts of Lapis Micae Aureuses, 100 parts of Herba galii veris, 110 parts of Crusta Penaeus seu Panulirus money, 70 parts of Herba Pentanematis Indicis, 45 parts of Flos Magnoliae Officinalises, 90 parts of halites, 150 parts of Radix Lantanae Camaraevs, 200 parts of Herba Polycarpaeae Corymbosaes, 70 parts of Banana Roots, 115 parts of Radix Trichosanthis Cucumeroidiss, 100 parts of Medulla Juncis, 65 parts of Cladonia fallax Abbayess, 35 parts of Radix berchemiae lineataes, described western medicine composition comprises following component: 5 parts of fluoxetine Hydrochlorides, 5 parts of N-acetylcysteins, 3.5 parts of naproxen sodiums, 7.5 parts of glutamic acid, 10 parts of citrulline, 4 parts of sodium citrate, 1.6 parts of iron supplementary, 1.0 parts of folic acid, 1.6 parts of nourishing additive agents.

Wherein, described iron supplementary is ferrum glycinate, and iron supplement can improve feminine menstrual anemia.Described nourishing additive agent is vitamin B6, vitamin B12, beta-carotene, and the part by weight between three is 2.5:2:3.5, appropriate vitimin supplement, can promote to increase energy, enhancing immunity with citrulline combined effect.

The extraction preparation method of described Chinese medicine ingredients is:

(2) pulverize with pulverizer, cross 70 mesh sieves, obtain mixed-powder, with the water soaking 7.5h relative to mixed-powder weight 11 times;

(3) mixed-powder drops into multi-function extractor together with the water soaked, heating decocts, decocting time is 2.5h, filter, gained filtering residue adds, relative to the water of mixed-powder weight 6.5 times, medical material is decocted 1.5h, filters, gained filtering residue adds, relative to the water of mixed-powder weight 2.5 times, medical material is decocted 1.0h, filter, above-mentioned three times are filtered the medicinal liquid mixing obtained, be concentrated into 57.5%.

(4) in step (3) extraction concentrated solution adds, the ethanol that concentration is 80% is entered, concentrated solution alcohol content is made to reach 67.5%, after having precipitate to occur, continue to leave standstill 27h, after thing to be precipitated fully precipitates, extract supernatant out, supernatant reclaims ethanol extremely without alcohol taste, reconcentration becomes fluid extract, and spraying dry makes extract powder, namely obtains described Chinese medicine ingredients.

(5) described Chinese medicine ingredients is mixed in dispensing canister with fluoxetine Hydrochloride, N-acetylcystein, naproxen sodium, glutamic acid, citrulline, 2 sodium citrate, ferrum glycinate, folic acid, nourishing additive agent, add pharmaceutical carrier 210 parts, dispersant 59 parts, antiseptic 0.2 part, obtain semi-finished product, then make hard capsule.Described pharmaceutically suitable carrier is carboxymethyl starch sodium, can help medicine molding, and reduces drug degradation and loss, reduces side effect, improves bioavailability.Described dispersant is polyethylene glycols, can improve medicine dispersive property.Described antiseptic is parabens, can extend the quality guarantee period of medicament phase.

Embodiment 3:

A kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 180 parts of Colysis bonii Ching., 100 parts of Radix Daphniphylli calycinis, 300 parts of Caulis et Folium Pulsatillaes, 300 parts of Herba Tricyrtis Pilosaes, 200 portions of awns, 150 parts of Herba Potentillae Fragarioidiss, 150 parts of Folium Aucubae chinensis roots, 200 parts of Radix Ilicis Asprellae rattans, 60 parts of Chinese fanpalm seeds, 90 parts of Lapis Micae Aureuses, 150 parts of Herba galii veris, 150 parts of Crusta Penaeus seu Panulirus money, 100 parts of Herba Pentanematis Indicis, 60 parts of Flos Magnoliae Officinalises, 150 parts of halites, 200 parts of Radix Lantanae Camaraevs, 250 parts of Herba Polycarpaeae Corymbosaes, 100 parts of Banana Roots, 150 parts of Radix Trichosanthis Cucumeroidiss, 150 parts of Medulla Juncis, 100 parts of Cladonia fallax Abbayess, 50 parts of Radix berchemiae lineataes, described western medicine composition comprises following component: 7 parts of fluoxetine Hydrochlorides, 8 parts of N-acetylcysteins, 6 parts of naproxen sodiums, 10 parts of glutamic acid, 15 parts of citrulline, 5.5 parts of sodium citrate, 2.4 parts of iron supplementary, 1.5 parts of folic acid, 2.0 parts of nourishing additive agents.

Wherein, described iron supplementary is ferrum glycinate, and iron supplement can improve feminine menstrual anemia.Described nourishing additive agent is vitamin B6, vitamin B12, beta-carotene, and the part by weight between three is 3:3:2, appropriate vitimin supplement, can promote to increase energy, enhancing immunity with citrulline combined effect.

The extraction preparation method of described Chinese medicine ingredients is:

(2) pulverize with pulverizer, cross 100 mesh sieves, obtain mixed-powder, with the water soaking 10h relative to mixed-powder weight 12 times;

(3) mixed-powder drops into multi-function extractor together with the water soaked, heating decocts, decocting time is 3h, filter, gained filtering residue adds, relative to the water of mixed-powder weight 8 times, medical material is decocted 2h, filters, gained filtering residue adds, relative to the water of mixed-powder weight 3 times, medical material is decocted 1.5h, filter, above-mentioned three times are filtered the medicinal liquid mixing obtained, be concentrated into 60%.

(4) in step (3) extraction concentrated solution adds, the ethanol that concentration is 85% is entered, concentrated solution alcohol content is made to reach 70%, after having precipitate to occur, continue to leave standstill 30h, after thing to be precipitated fully precipitates, extract supernatant out, supernatant reclaims ethanol extremely without alcohol taste, reconcentration becomes fluid extract, and spraying dry makes extract powder, namely obtains described Chinese medicine ingredients.

(5) described Chinese medicine ingredients is mixed in dispensing canister with fluoxetine Hydrochloride, N-acetylcystein, naproxen sodium, glutamic acid, citrulline, 2 sodium citrate, ferrum glycinate, folic acid, nourishing additive agent, add pharmaceutical carrier 300 parts, dispersant 70 parts, antiseptic 0.3 part, obtain semi-finished product, then make soft capsule.Described pharmaceutically suitable carrier is sodium lauryl sulphate, can help medicine molding, and reduces drug degradation and loss, reduces side effect, improves bioavailability.Described dispersant is polyethylene glycols, can improve medicine dispersive property.Described antiseptic is potassium sorbate, can extend the quality guarantee period of medicament phase.

Embodiment 4:

A kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 80 parts of Colysis bonii Ching., 30 parts of Radix Daphniphylli calycinis, 150 parts of Caulis et Folium Pulsatillaes, 100 parts of Herba Tricyrtis Pilosaes, 120 portions of awns, 90 parts of Herba Potentillae Fragarioidiss, 100 parts of Folium Aucubae chinensis roots, 100 parts of Radix Ilicis Asprellae rattans, 20 parts of Chinese fanpalm seeds, 30 parts of Lapis Micae Aureuses, 50 parts of Herba galii veris, 70 parts of Crusta Penaeus seu Panulirus money, 40 parts of Herba Pentanematis Indicis, 30 parts of Flos Magnoliae Officinalises, 60 parts of halites, 100 parts of Radix Lantanae Camaraevs, 150 parts of Herba Polycarpaeae Corymbosaes, 40 parts of Banana Roots, 80 parts of Radix Trichosanthis Cucumeroidiss, 50 parts of Medulla Juncis, 30 parts of Cladonia fallax Abbayess, 20 parts of Radix berchemiae lineataes, 60 parts of Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendles, 100 Fen Herba Cirsii Linearis, 100 parts of Macaranga tanarius, 30 parts of Pericarpium Citri grandiss, described western medicine composition comprises following component: 3 parts of fluoxetine Hydrochlorides, 2 parts of N-acetylcysteins, 1 part of naproxen sodium, 5 parts of glutamic acid, 5 parts of citrulline, 2.5 parts of sodium citrate, 0.8 part of iron supplementary, 0.5 part of folic acid, 1.2 parts of nourishing additive agents.

The extraction preparation method of described Chinese medicine ingredients is:

(1) get the Colysis bonii Ching. of formula ratio, Radix Daphniphylli calycini, Caulis et Folium Pulsatillae, Herba Tricyrtis Pilosae, awns spent, Herba Potentillae Fragarioidis, Folium Aucubae chinensis root, Radix Ilicis Asprellae rattan, Chinese fanpalm seed, Lapis Micae Aureus, Herba galii veri, Crusta Penaeus seu Panulirus money, Herba Pentanematis Indici, Flos Magnoliae Officinalis, halite, Radix Lantanae Camaraev, Herba Polycarpaeae Corymbosae, Banana Root, Radix Trichosanthis Cucumeroidis, Medulla Junci, Cladonia fallax Abbayes, Radix berchemiae lineatae, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle, Herba Cirsii Linearis, Macaranga tanarius, Pericarpium Citri grandis, clean up with the tap water of flowing, pull out, dry;

Embodiment 5:

A kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 130 parts of Colysis bonii Ching., 65 parts of Radix Daphniphylli calycinis, 225 parts of Caulis et Folium Pulsatillaes, 200 parts of Herba Tricyrtis Pilosaes, 160 portions of awns, 120 parts of Herba Potentillae Fragarioidiss, 125 parts of Folium Aucubae chinensis roots, 150 parts of Radix Ilicis Asprellae rattans, 40 parts of Chinese fanpalm seeds, 60 parts of Lapis Micae Aureuses, 100 parts of Herba galii veris, 110 parts of Crusta Penaeus seu Panulirus money, 70 parts of Herba Pentanematis Indicis, 45 parts of Flos Magnoliae Officinalises, 90 parts of halites, 150 parts of Radix Lantanae Camaraevs, 200 parts of Herba Polycarpaeae Corymbosaes, 70 parts of Banana Roots, 115 parts of Radix Trichosanthis Cucumeroidiss, 100 parts of Medulla Juncis, 65 parts of Cladonia fallax Abbayess, 35 parts of Radix berchemiae lineataes, 120 parts of Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendles, 150 Fen Herba Cirsii Linearis, 125 parts of Macaranga tanarius, 60 parts of Pericarpium Citri grandiss, described western medicine composition comprises following component: 5 parts of fluoxetine Hydrochlorides, 5 parts of N-acetylcysteins, 3.5 parts of naproxen sodiums, 7.5 parts of glutamic acid, 10 parts of citrulline, 4 parts of sodium citrate, 1.6 parts of iron supplementary, 1.0 parts of folic acid, 1.6 parts of nourishing additive agents.

The extraction preparation method of described Chinese medicine ingredients is:

Embodiment 6:

A kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 180 parts of Colysis bonii Ching., 100 parts of Radix Daphniphylli calycinis, 300 parts of Caulis et Folium Pulsatillaes, 300 parts of Herba Tricyrtis Pilosaes, 200 portions of awns, 150 parts of Herba Potentillae Fragarioidiss, 150 parts of Folium Aucubae chinensis roots, 200 parts of Radix Ilicis Asprellae rattans, 60 parts of Chinese fanpalm seeds, 90 parts of Lapis Micae Aureuses, 150 parts of Herba galii veris, 150 parts of Crusta Penaeus seu Panulirus money, 100 parts of Herba Pentanematis Indicis, 60 parts of Flos Magnoliae Officinalises, 150 parts of halites, 200 parts of Radix Lantanae Camaraevs, 250 parts of Herba Polycarpaeae Corymbosaes, 100 parts of Banana Roots, 150 parts of Radix Trichosanthis Cucumeroidiss, 150 parts of Medulla Juncis, 100 parts of Cladonia fallax Abbayess, 50 parts of Radix berchemiae lineataes, 180 parts of Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendles, 200 Fen Herba Cirsii Linearis, 150 parts of Macaranga tanarius, 90 parts of Pericarpium Citri grandiss, described western medicine composition comprises following component: 7 parts of fluoxetine Hydrochlorides, 8 parts of N-acetylcysteins, 6 parts of naproxen sodiums, 10 parts of glutamic acid, 15 parts of citrulline, 5.5 parts of sodium citrate, 2.4 parts of iron supplementary, 1.5 parts of folic acid, 2.0 parts of nourishing additive agents.

The extraction preparation method of described Chinese medicine ingredients is:

Embodiment 7:

A kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 80 parts of Colysis bonii Ching., 30 parts of Radix Daphniphylli calycinis, 150 parts of Caulis et Folium Pulsatillaes, 100 parts of Herba Tricyrtis Pilosaes, 120 portions of awns, 90 parts of Herba Potentillae Fragarioidiss, 100 parts of Folium Aucubae chinensis roots, 100 parts of Radix Ilicis Asprellae rattans, 20 parts of Chinese fanpalm seeds, 30 parts of Lapis Micae Aureuses, 50 parts of Herba galii veris, 70 parts of Crusta Penaeus seu Panulirus money, 40 parts of Herba Pentanematis Indicis, 30 parts of Flos Magnoliae Officinalises, 60 parts of halites, 100 parts of Radix Lantanae Camaraevs, 150 parts of Herba Polycarpaeae Corymbosaes, 40 parts of Banana Roots, 80 parts of Radix Trichosanthis Cucumeroidiss, 50 parts of Medulla Juncis, 30 parts of Cladonia fallax Abbayess, 20 parts of Radix berchemiae lineataes, 40 parts of Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) roots, 30 parts of Rhizoma soulieae vaginataes, 50 parts of Herba Hippuridis Vulgaris, 60 parts of Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendles, 100 Fen Herba Cirsii Linearis, 100 parts of Macaranga tanarius, 30 parts of Pericarpium Citri grandiss, described western medicine composition comprises following component: 3 parts of fluoxetine Hydrochlorides, 2 parts of N-acetylcysteins, 1 part of naproxen sodium, 5 parts of glutamic acid, 5 parts of citrulline, 2.5 parts of sodium citrate, 0.8 part of iron supplementary, 0.5 part of folic acid, 1.2 parts of nourishing additive agents.

The extraction preparation method of described Chinese medicine ingredients is:

(1) get the Colysis bonii Ching. of formula ratio, Radix Daphniphylli calycini, Caulis et Folium Pulsatillae, Herba Tricyrtis Pilosae, awns spent, Herba Potentillae Fragarioidis, Folium Aucubae chinensis root, Radix Ilicis Asprellae rattan, Chinese fanpalm seed, Lapis Micae Aureus, Herba galii veri, Crusta Penaeus seu Panulirus money, Herba Pentanematis Indici, Flos Magnoliae Officinalis, halite, Radix Lantanae Camaraev, Herba Polycarpaeae Corymbosae, Banana Root, Radix Trichosanthis Cucumeroidis, Medulla Junci, Cladonia fallax Abbayes, Radix berchemiae lineatae, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle, Herba Cirsii Linearis, Macaranga tanarius, Pericarpium Citri grandis, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, Rhizoma soulieae vaginatae, Herba Hippuridis Vulgaris, clean up with the tap water of flowing, pull out, dry;

Embodiment 8:

A kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 130 parts of Colysis bonii Ching., 65 parts of Radix Daphniphylli calycinis, 225 parts of Caulis et Folium Pulsatillaes, 200 parts of Herba Tricyrtis Pilosaes, 160 portions of awns, 120 parts of Herba Potentillae Fragarioidiss, 125 parts of Folium Aucubae chinensis roots, 150 parts of Radix Ilicis Asprellae rattans, 40 parts of Chinese fanpalm seeds, 60 parts of Lapis Micae Aureuses, 100 parts of Herba galii veris, 110 parts of Crusta Penaeus seu Panulirus money, 70 parts of Herba Pentanematis Indicis, 45 parts of Flos Magnoliae Officinalises, 90 parts of halites, 150 parts of Radix Lantanae Camaraevs, 200 parts of Herba Polycarpaeae Corymbosaes, 70 parts of Banana Roots, 115 parts of Radix Trichosanthis Cucumeroidiss, 100 parts of Medulla Juncis, 65 parts of Cladonia fallax Abbayess, 35 parts of Radix berchemiae lineataes, 70 parts of Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) roots, 60 parts of Rhizoma soulieae vaginataes, 75 parts of Herba Hippuridis Vulgaris, 120 parts of Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendles, 150 Fen Herba Cirsii Linearis, 125 parts of Macaranga tanarius, 60 parts of Pericarpium Citri grandiss, described western medicine composition comprises following component: 5 parts of fluoxetine Hydrochlorides, 5 parts of N-acetylcysteins, 3.5 parts of naproxen sodiums, 7.5 parts of glutamic acid, 10 parts of citrulline, 4 parts of sodium citrate, 1.6 parts of iron supplementary, 1.0 parts of folic acid, 1.6 parts of nourishing additive agents.

The extraction preparation method of described Chinese medicine ingredients is:

Embodiment 9:

A kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 180 parts of Colysis bonii Ching., 100 parts of Radix Daphniphylli calycinis, 300 parts of Caulis et Folium Pulsatillaes, 300 parts of Herba Tricyrtis Pilosaes, 200 portions of awns, 150 parts of Herba Potentillae Fragarioidiss, 150 parts of Folium Aucubae chinensis roots, 200 parts of Radix Ilicis Asprellae rattans, 60 parts of Chinese fanpalm seeds, 90 parts of Lapis Micae Aureuses, 150 parts of Herba galii veris, 150 parts of Crusta Penaeus seu Panulirus money, 100 parts of Herba Pentanematis Indicis, 60 parts of Flos Magnoliae Officinalises, 150 parts of halites, 200 parts of Radix Lantanae Camaraevs, 250 parts of Herba Polycarpaeae Corymbosaes, 100 parts of Banana Roots, 150 parts of Radix Trichosanthis Cucumeroidiss, 150 parts of Medulla Juncis, 100 parts of Cladonia fallax Abbayess, 50 parts of Radix berchemiae lineataes, 100 parts of Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) roots, 90 parts of Rhizoma soulieae vaginataes, 100 parts of Herba Hippuridis Vulgaris, 180 parts of Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendles, 200 Fen Herba Cirsii Linearis, 150 parts of Macaranga tanarius, 90 parts of Pericarpium Citri grandiss, described western medicine composition comprises following component: 7 parts of fluoxetine Hydrochlorides, 8 parts of N-acetylcysteins, 6 parts of naproxen sodiums, 10 parts of glutamic acid, 15 parts of citrulline, 5.5 parts of sodium citrate, 2.4 parts of iron supplementary, 1.5 parts of folic acid, 2.0 parts of nourishing additive agents.

The extraction preparation method of described Chinese medicine ingredients is:

Clinical treatment typical case:

Case 1: Wang, female, 37 years old, suffer from menstrual psychosis menstruation psychosis and reach 6 years, fell ill premenstrual 2 weeks of the moon at every turn, anxious state of mind, dysphoria, with headache, the symptom such as dizzy, each morbidity is in the past treated with regard to long-term steroid class Western medicine, after medication, the state of an illness obtains certain alleviation, but still can recur, cannot effect a radical cure, of the present invention for after 1 course for the treatment of of Chinese medicine and western medicine compound preparation of menstrual psychosis menstruation psychosis by taking, headache, dizzy transference cure such as grade, anxious state of mind, the symptoms such as dysphoria are effectively alleviated, before next menstrual cycle, anxious state of mind, the symptoms such as dysphoria all disappear, basic healing, take medicine continuously 3 cycles, later observation 6 months, have no recurrence.

Case 2: Huang, female, 41 years old, suffer from menstrual psychosis menstruation psychosis for 10 years, fell ill premenstrual 2 weeks of the moon at every turn, anxious state of mind, hallucinate, there is obvious incoordination locomotor stimulatory, language disorder, the rapid spontaneous remission when menstrual onset, never treat, the state of an illness is more serious, of the present invention for after 1 course for the treatment of of Chinese medicine and western medicine compound preparation of menstrual psychosis menstruation psychosis by taking, various symptom obtains certain alleviation, continue 1 course for the treatment of of medication, various symptom is improved greatly, be used in conjunction 3 all after dates, all symptoms all disappear, later observation 6 months, have no recurrence.

Case 3: Lin, female, 33 years old, suffer from menstrual psychosis menstruation psychosis 7 years, fell ill premenstrual 2 weeks of the moon at every turn, the state of an illness is comparatively serious, in epilepsy seizure, there is obvious elation or low, there is obvious incoordination locomotor stimulatory, conduct disorder, and cause infertile, long-term steroid class medicine is treated always, but have no improvement, of the present invention for after 1 course for the treatment of of Chinese medicine and western medicine compound preparation of menstrual psychosis menstruation psychosis by taking, various symptom obtains certain alleviation, continue 1 course for the treatment of of medication, various symptom is improved greatly, be used in conjunction 3 all after dates, all symptoms all disappear, later observation 6 months, have no recurrence.

Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in previous embodiment, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of embodiment of the present invention technical scheme.

Claims

1. the Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis, it is characterized in that, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 80 ~ 180 parts of Colysis bonii Ching., 30 ~ 100 parts of Radix Daphniphylli calycinis, 150 ~ 300 parts of Caulis et Folium Pulsatillaes, 100 ~ 300 parts of Herba Tricyrtis Pilosaes, 120 ~ 200 portions of awns, 90 ~ 150 parts of Herba Potentillae Fragarioidiss, 100 ~ 150 parts of Folium Aucubae chinensis roots, 100 ~ 200 parts of Radix Ilicis Asprellae rattans, 20 ~ 60 parts of Chinese fanpalm seeds, 30 ~ 90 parts of Lapis Micae Aureuses, 50 ~ 150 parts of Herba galii veris, 70 ~ 150 parts of Crusta Penaeus seu Panulirus money, 40 ~ 100 parts of Herba Pentanematis Indicis, 30 ~ 60 parts of Flos Magnoliae Officinalises, 60 ~ 150 parts of halites, 100 ~ 200 parts of Radix Lantanae Camaraevs, 150 ~ 250 parts of Herba Polycarpaeae Corymbosaes, 40 ~ 100 parts of Banana Roots, 80 ~ 150 parts of Radix Trichosanthis Cucumeroidiss, 50 ~ 150 parts of Medulla Juncis, 30 ~ 100 parts of Cladonia fallax Abbayess, 20 ~ 50 parts of Radix berchemiae lineataes, described western medicine composition comprises following component: 3 ~ 7 parts of fluoxetine Hydrochlorides, 2 ~ 8 parts of N-acetylcysteins, 1 ~ 6 part of naproxen sodium, 5 ~ 10 parts of glutamic acid, 5 ~ 15 parts of citrulline, 2.5 ~ 5.5 parts of sodium citrate, 0.8 ~ 2.4 part of iron supplementary, 0.5 ~ 1.5 part of folic acid, 1.2 ~ 2.0 parts of nourishing additive agents.

2. a kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis as claimed in claim 1, it is characterized in that, be made up of Chinese medicine ingredients and western medicine composition, by weight, described Chinese medicine ingredients is mainly extracted by following crude drug and is prepared from: 80 ~ 180 parts of Colysis bonii Ching., 30 ~ 100 parts of Radix Daphniphylli calycinis, 150 ~ 300 parts of Caulis et Folium Pulsatillaes, 100 ~ 300 parts of Herba Tricyrtis Pilosaes, 120 ~ 200 portions of awns, 90 ~ 150 parts of Herba Potentillae Fragarioidiss, 100 ~ 150 parts of Folium Aucubae chinensis roots, 100 ~ 200 parts of Radix Ilicis Asprellae rattans, 20 ~ 60 parts of Chinese fanpalm seeds, 30 ~ 90 parts of Lapis Micae Aureuses, 50 ~ 150 parts of Herba galii veris, 70 ~ 150 parts of Crusta Penaeus seu Panulirus money, 40 ~ 100 parts of Herba Pentanematis Indicis, 30 ~ 60 parts of Flos Magnoliae Officinalises, 60 ~ 150 parts of halites, 100 ~ 200 parts of Radix Lantanae Camaraevs, 150 ~ 250 parts of Herba Polycarpaeae Corymbosaes, 40 ~ 100 parts of Banana Roots, 80 ~ 150 parts of Radix Trichosanthis Cucumeroidiss, 50 ~ 150 parts of Medulla Juncis, 30 ~ 100 parts of Cladonia fallax Abbayess, 20 ~ 50 parts of Radix berchemiae lineataes, 40 ~ 100 parts of Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) roots, 30 ~ 90 parts of Rhizoma soulieae vaginataes, 50 ~ 100 parts of Herba Hippuridis Vulgaris, described western medicine composition comprises following component: 3 ~ 7 parts of fluoxetine Hydrochlorides, 2 ~ 8 parts of N-acetylcysteins, 1 ~ 6 part of naproxen sodium, 5 ~ 10 parts of glutamic acid, 5 ~ 15 parts of citrulline, 2.5 ~ 5.5 parts of sodium citrate, 0.8 ~ 2.4 part of iron supplementary, 0.5 ~ 1.5 part of folic acid, 1.2 ~ 2.0 parts of nourishing additive agents.

3. a kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis as claimed in claim 1 or 2, it is characterized in that, described iron supplementary is ferrum glycinate.

4. a kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis as claimed in claim 1 or 2, it is characterized in that, described nourishing additive agent is vitamin B6, vitamin B12, beta-carotene, and the part by weight between three is (2 ~ 3): (1 ~ 3): (2 ~ 5).

5. a kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis as claimed in claim 1 or 2, it is characterized in that, the extraction preparation method of described Chinese medicine ingredients is:

(1) get the Colysis bonii Ching. of formula ratio, Radix Daphniphylli calycini, Caulis et Folium Pulsatillae, Herba Tricyrtis Pilosae, awns spent, Herba Potentillae Fragarioidis, Folium Aucubae chinensis root, Radix Ilicis Asprellae rattan, Chinese fanpalm seed, Lapis Micae Aureus, Herba galii veri, Crusta Penaeus seu Panulirus money, Herba Pentanematis Indici, Flos Magnoliae Officinalis, halite, Radix Lantanae Camaraev, Herba Polycarpaeae Corymbosae, Banana Root, Radix Trichosanthis Cucumeroidis, Medulla Junci, Cladonia fallax Abbayes, Radix berchemiae lineatae, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, Rhizoma soulieae vaginatae, Herba Hippuridis Vulgaris, clean up with the tap water of flowing, pull out, dry;

6. a kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis as claimed in any one of claims 1 to 5, wherein, it is characterized in that, preparation method is:

7. a kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis as claimed in claim 6, it is characterized in that, described pharmaceutically suitable carrier is any one or two or more mixture in following composition: s6, carboxymethyl starch sodium, sodium lauryl sulphate.

8. a kind of Chinese medicine and western medicine compound preparation for menstrual psychosis menstruation psychosis as claimed in claim 6, it is characterized in that, described dispersant is polyethylene glycols.

9. a kind of Chinese medicine and western medicine compound preparation for the treatment of chronic pelvic inflammatory disease as claimed in claim 6, it is characterized in that, described antiseptic is parabens or potassium sorbate.