CN103479955B - A kind of medicine of strengthening the spleen to promote digestion - Google Patents

A kind of medicine of strengthening the spleen to promote digestion Download PDF

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Publication number
CN103479955B
CN103479955B CN201310462743.6A CN201310462743A CN103479955B CN 103479955 B CN103479955 B CN 103479955B CN 201310462743 A CN201310462743 A CN 201310462743A CN 103479955 B CN103479955 B CN 103479955B
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parts
radix
spleen
medicine
rhizoma
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CN103479955A (en
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不公告发明人
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Wuhan Hong Xintong Science And Technology Ltd
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Abstract

The medicine that the invention discloses a kind of strengthening the spleen to promote digestion is the medicament be made up of the crude drug of following parts by weight: Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Semen Coicis 30 parts, Rhizoma Coptidis 10 parts, Herba Taraxaci 30 parts, Radix Angelicae Sinensis 15 parts, Radix Glycyrrhizae Preparata 6 parts, Herba Dendrobii 20 parts, the Cortex Eucommiae 15 parts, Radix Scutellariae 10 parts, Radix Dipsaci 15 parts, 15 parts, Poria, Semen Oroxyli 10 parts, Cortex Magnoliae Officinalis 10 parts, Ramulus Cinnamomi 10 parts, Herba Agrimoniae 30 parts, Fructus Amomi 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, the Radix Paeoniae Alba 15 parts, Semen Lablab Album 15 parts and Fructus Aurantii 10 parts.This medicine creates beyond thought effect in strengthening the spleen to promote digestion.

Description

A kind of medicine of strengthening the spleen to promote digestion
Technical field
The present invention relates to technical field of Chinese medicines, be specially a kind of medicine of strengthening the spleen to promote digestion.
Background technology
Insufficiency of the spleen then dysfunction of the spleen in transportation and transformation, and can occur malnutrition, water liquid loses rawly in spreading wetly makes expectorant, or the disease such as to lose blood.Its disease is at stomach, and dyspepsia relates to the internal organs such as liver spleen, and suitable determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, gives invigorating the spleen and regulating the stomach, depressed liver-energy dispersing and QI regulating, the method treatments such as dyspepsia and intestinal stasis relieving.But western medicine side effect is comparatively large, market similar Chinese patent medicine DeGrain.
Summary of the invention
The object of the invention is, in order to overcome above-mentioned the deficiencies in the prior art part, to provide a kind of medicine of strengthening the spleen to promote digestion according to Chinese medical theory.
The medicine of strengthening the spleen to promote digestion of the present invention is the medicament be made up of the crude drug of following parts by weight:
Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Semen Coicis 30 parts, Rhizoma Coptidis 10 parts, Herba Taraxaci 30 parts, Radix Angelicae Sinensis 15 parts, Radix Glycyrrhizae Preparata 6 parts, Herba Dendrobii 20 parts, the Cortex Eucommiae 15 parts, Radix Scutellariae 10 parts, Radix Dipsaci 15 parts, 15 parts, Poria, Semen Oroxyli 10 parts, Cortex Magnoliae Officinalis 10 parts, Ramulus Cinnamomi 10 parts, Herba Agrimoniae 30 parts, Fructus Amomi 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, the Radix Paeoniae Alba 15 parts, Fructus Aurantii 10 parts and Semen Lablab Album 15 parts.
Described medicament is capsule.
The preparation method of medicine of the present invention is:
Get crude drug Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Semen Coicis 30 parts, Rhizoma Coptidis 10 parts, Herba Taraxaci 30 parts, Radix Angelicae Sinensis 15 parts, Radix Glycyrrhizae Preparata 6 parts, Herba Dendrobii 20 parts, the Cortex Eucommiae 15 parts, Radix Scutellariae 10 parts, Radix Dipsaci 15 parts, 15 parts, Poria, Semen Oroxyli 10 parts, Cortex Magnoliae Officinalis 10 parts, Ramulus Cinnamomi 10 parts, Herba Agrimoniae 30 parts, Fructus Amomi 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, the Radix Paeoniae Alba 15 parts, Fructus Aurantii 10 parts and Semen Lablab Album 15 parts by weight for subsequent use;
Second step: after being mixed by above-mentioned raw materials medicine, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate.
Strengthening the spleen to promote digestion Chinese medicine composition provided by the invention, its raw material is Radix Astragali, Rhizoma Dioscoreae, Rhizoma Atractylodis Macrocephalae (parched), Semen Coicis, Rhizoma Coptidis, Herba Taraxaci, Radix Angelicae Sinensis, Radix Glycyrrhizae Preparata, Herba Dendrobii, the Cortex Eucommiae, Radix Scutellariae, Radix Dipsaci, Poria, Semen Oroxyli, Cortex Magnoliae Officinalis, Ramulus Cinnamomi, Herba Agrimoniae, Fructus Amomi, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Paeoniae Alba, Fructus Aurantii and Semen Lablab Album, can be used for the vomiting for the treatment of because insufficiency of the spleen and dyspepsia cause, abdominal distention and becoming thin, effect of what above-mentioned medical material had have certain strengthening the spleen to promote digestion, the effect with certain building body had, this formula is in R&D process, with the formula in the patent of applying on the same day for core, by the additional formulations that increase and decrease flavour of a drug and adjustment compatibility relationship draw, wherein Semen Lablab Album has spleen reinforcing to dehumidify, Semen Coicis can spleen reinforcing eliminating dampness by diuresis.Semen Lablab Album, Semen Coicis is compatible with this ratio, eliminating dampness and diuresis contributes to treatment and has loose bowels, work is handed over to have good action for vomiting and diarrhoea, and the Rhizoma Dioscoreae effect of reinforcing the kidney itself, add Rhizoma Dioscoreae and Semen Lablab Album matches as ministerial drug and monarch drug Semen Coicis, because after insufficiency of the spleen inability of food and drink to be digested and transported vital essence, there is water to wet dirty, an astringency inducing be had.So after carrying out the compatibility of rational proportion with above-mentioned raw materials medicine according to the combination principle of monarch, enhance spleen reinforcing exsiccation.Because Seem Lablab Album can removing dampness also can dampness removing, beyond Semen Coicis spleen reinforcing, dampness removing is main.After carrying out the compatibility of rational proportion with above-mentioned raw materials medicine according to the combination principle of monarch, should say that QI invigorating dehumidifying strength is much bigger.And picture Rhizoma Dioscoreae this class, on can lung moistening, in can spleen reinforcing, can to reinforce the kidney down, to look after more comprehensive.Achieve at treatment insufficiency of the spleen, dyspepsia, vomiting, abdominal distention with in becoming thin etc. the curative effect showed, make this medicine in strengthening the spleen to promote digestion, create beyond thought effect.And the present invention is pure Chinese medicinal preparation, observed through 1 year both without recurring also without obvious toxic and side effects.
Detailed description of the invention
A medicine for strengthening the spleen to promote digestion, be made up of following bulk drugs:
Radix Astragali 30g, Rhizoma Dioscoreae 30g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Semen Coicis 30g, Rhizoma Coptidis 10g, Herba Taraxaci 30g, Radix Angelicae Sinensis 15g, Radix Glycyrrhizae Preparata 6g, Herba Dendrobii 20g, Cortex Eucommiae 15g, Radix Scutellariae 10g, Radix Dipsaci 15g, Poria 15g, Semen Oroxyli 10g, Cortex Magnoliae Officinalis 10g, Ramulus Cinnamomi 10g, Herba Agrimoniae 30g, Fructus Amomi 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Radix Paeoniae Alba 15g, Fructus Aurantii 10g and Semen Lablab Album 10g;
Second step: after being mixed by above-mentioned raw materials medicine, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate.Every capsule has above-mentioned raw materials medicine 0.4g.
The drug effect of each taste crude drug is as follows:
1. Radix Astragali: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
2. Rhizoma Dioscoreae: spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.
3. Rhizoma Atractylodis Macrocephalae (parched): invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.
4. Semen Coicis: spleen invigorating, eliminating dampness by diuresis, antidiarrheal, evacuation of pus.
5. Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.
6. Herba Taraxaci: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.
7. Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
8. Radix Glycyrrhizae Preparata: spleen reinforcing stomach function regulating, Yiqi and vein recovery.
9. Herba Dendrobii: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.
10. the Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening, antiabortive.
11. Radix Scutellariaes: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.
12. Radix Dipsacis: invigorating the liver and kidney, bone and muscle strengthening, continuous injured, only metrorrhagia.
13. Poria: Poria slightly sweet flavor is put down, and enters the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.
14. Semen Oroxylis: lung moistening, soothing liver-QI, stomach function regulating, granulation promoting.
15. Cortex Magnoliae Officinalis: dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.
16. Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.
17. Herba Agrimoniaes: astringing to arrest bleeding, detoxification sore treatment, parasite killing, puckery antiperspirant, cough-relieving.
18. Fructus Amomis: removing dampness is whetted the appetite, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive.
19. Pseudobulbus Bletillae (Rhizoma Bletillae)s: tonifying the lung, relieving cough and resolving phlegm, hemostasia and promoting granulation.
20. Radix Paeoniae Albas: nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant.
21. Fructus Aurantiis: regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.
22. Semen Lablab Albums: spleen reinforcing and in, removing dampness is relieved summer heat.
Instructions of taking: the people of more than 18 years old three times on the one, each 1.Within 30 days, be a course for the treatment of, take three courses for the treatment of continuously.As taken 1 week symptom continuously without obviously changing or occurring that diarrhoea and vomiting increase the weight of after taking medicine, should drug withdrawal immediately, transference cure after drug withdrawal.
Clinical trial:
Choose 150 routine functional dyspepsias and with gastrointestinal upset as vomiting, abdominal distention and the Patients of Spleen Deficiency of becoming thin, age 18-50 year, the course of disease more than 3 months, did not carry out any treatment in 2 months.Above-mentioned 150 routine patients are divided into treatment group and matched group two groups, treatment group 100 example, the capsule obtained with this enforcement is treated, and three times on the oral one, each 1 30 days is a course for the treatment of, takes three courses for the treatment of continuously.Matched group 50 example, takes domperidone tablet treatment: oral, 10 ~ 20mg or suspension 10ml, every day 3 ~ 4 times, 15 ~ 30 minutes ante cibum took, and within 15 days, were a course for the treatment of, took three courses for the treatment of continuously.Then clinical observation is carried out.
Period in a medicine treatment group self clinical observation on the therapeutic effect analysis result is as follows:
Curative effect project Treatment group number of cases Improvement rate (%)
Vomiting number of times reduces 90 90%
Abdominal distention is alleviated 86 86%
Body weight increases 88 88%
Appetite increases 96 96%
Total improvement rate (%) 90%
The clinical observation on the therapeutic effect analysis result of period in a medicine treatment group and matched group is as follows:
Efficacy assessment standard is as follows:
1, effective: vomiting is obviously controlled, and abdominal distention is obviously alleviated, body weight increases, and appetite increases, the transference cure of all the other gastrointestinal upsets.
2, take a turn for the better: vomiting number of times reduces or the intermittent time extends, and abdominal distention is alleviated to some extent, body weight stops alleviating, and appetite makes moderate progress, and the symptom partial symptoms of all the other gastrointestinal upsets disappears.
3, invalid: symptom is without improvement or increase the weight of.
The comparison sheet of the clinical medicine incidence of side effects of period in a medicine treatment group and matched group
Stomachache and Refuse to take medicine are clinical modal side effect as can be seen from the above table, but can progressively disappear after drug withdrawal.But tremble and the incidence rate of side effect of having blood in stool, take the matched group of domperidone tablet apparently higher than the treatment group taking capsule of the present invention, so the present invention does not have obvious toxic and side effects substantially.

Claims (2)

1. a medicine for strengthening the spleen to promote digestion, is characterized in that it is the medicament be made up of the crude drug of following parts by weight:
Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Semen Coicis 30 parts, Rhizoma Coptidis 10 parts, Herba Taraxaci 30 parts, Radix Angelicae Sinensis 15 parts, Radix Glycyrrhizae Preparata 6 parts, Herba Dendrobii 20 parts, the Cortex Eucommiae 15 parts, Radix Scutellariae 10 parts, Radix Dipsaci 15 parts, 15 parts, Poria, Semen Oroxyli 10 parts, Cortex Magnoliae Officinalis 10 parts, Ramulus Cinnamomi 10 parts, Herba Agrimoniae 30 parts, Fructus Amomi 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, the Radix Paeoniae Alba 15 parts, Fructus Aurantii 10 parts and Semen Lablab Album 15 parts.
2. the medicine of strengthening the spleen to promote digestion according to claim 1, is characterized in that described medicament is capsule.
CN201310462743.6A 2013-09-30 2013-09-30 A kind of medicine of strengthening the spleen to promote digestion Expired - Fee Related CN103479955B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102772770B (en) * 2012-08-03 2013-12-04 刘元田 Traditional Chinese medicine composition for treating cold-damp affecting spleen syndrome

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Inventor after: Cui Yufeng

Inventor after: Zhao Xingwu

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Effective date of registration: 20161121

Address after: 262500 Yongchang street, Weifang, Shandong, Xiaoxinzhuang District, Qingzhou

Patentee after: Cui Yufeng

Patentee after: Yang Wenwen

Address before: 430000 Hubei city of Wuhan province Optics Valley East Lake New Technology Development Zone, Road No. 58 South Fuxing garden of medicine of 4 7 storey building No. 02

Patentee before: Wuhan Hong Xintong Science and Technology Ltd.

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