CN105106895A - Compound traditional Chinese medicine oral solution for treating nephritis and preparation process thereof - Google Patents
Compound traditional Chinese medicine oral solution for treating nephritis and preparation process thereof Download PDFInfo
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Abstract
The invention relates to a compound traditional Chinese medicinal oral solution for treating nephritis and a preparation process thereof. The compound traditional Chinese medicinal oral solution is mainly prepared from pilose antlers, a spicate clerodendranthus herb, peach blossoms, cinnamons and other natural Chinese herbal medicines through processing, is safe and effective, has no incompatibility, is free of medicine resistance and toxic and side effects, has the effects of tonifying qi, nourishing yin, nourishing blood, reinforcing spleen, soothing the nerves, moistening lung, warming the middle and tonifying yang, is suitable for treatment of acute or chronic nephritis, kidney failure and other symptoms caused by insufficiency of primordial qi, yin deficiency and less blood, yin and yang imbalance, liver-kidney deficiency, spleen insufficiency and damp and hot conditions, renal collateral stasis or toxin accumulation, treats both symptoms and root causes and is remarkable in effect. In addition, the prepared oral solution is subjected to high temperature sterilization, the preparation process is simple and can be popularized and used, and xylitol and cinnamon syrup serve as corrigents utilized to mask bitter and astringent taste of the traditional Chinese medicines and improve the compliance of patients.
Description
Technical field
The present invention relates to a kind of herbal mixture oral liquid for the treatment of nephritis, additionally provide the preparation technology of this medicine simultaneously, belong to compound Chinese medicinal preparation technical field.
Background technology
Nephritis is one group of disease of the renal failure caused due to nephridial tissue generation pathological changes or inflammation, at present along with the social pressure that people bear, life stress, operating pressure increases gradually, overtired diet is in addition unreasonable, and daily life system is irregular, makes kidney disease become the healthy a kind of stubborn disease of harm people, its clinical symptoms main manifestations is: face, eyelid, lower limb all occur edema, sick severe one edema involves whole body, and oliguria is anuria even, hematuria, hypertension, limbs fatigue, lassitude, feels sick, vomiting, lumbocrural pain etc.The age bracket that nephritis relates to is comparatively extensive, but general male's sickness rate is higher.
The traditional Chinese medical science thinks that the kidney being the origin of congenital constitution, kidney disease mainly due to kidney disorder, imbalance of YIN and YANG, deficiency of both the liver and kidney, insufficiency of the spleen damp and hot, cause poisonous substance water liquid cannot dredge, discharge, and cause toxin to store up, kidney network retardance, congestion.
At present, doctor trained in Western medicine mainly adopts antibiotic as Main Means treatment means, but antibiotic not only side effect is large, the state of an illness is easily repeatedly, and large to body injury, and long-term taking easily produces drug resistance.Natural herb Chinese medicine safety is cheap, have no drug resistance, have no side effect, effective solve that Current therapeutic is acute, the deficiency of chronic nephritis medicine, treating both the principal and secondary aspects of a disease, Be very effective.
summary of the invention:
The invention provides a kind of herbal mixture oral liquid for the treatment of nephritis, adopt natural Chinese medicinal herb, safe and effective, without incompatibility, have no drug resistance, have no side effect, effective solution Current therapeutic is acute, the deficiency of chronic nephritis medicine, clinical effectiveness is remarkable.
Invention further provides a kind of preparation technology treating the herbal mixture oral liquid of nephritis, preparation technology is simple, can promote the use of, xylitol, Cortex cinnamomi japonici (Ramulus Cinnamomi) syrup is utilized to cover the pained mouthfeel of Chinese medicine as correctives, patient's compliance can be improved, be applicable to insufficiency of primordial QI, deficiency of YIN insufficiency of blood, imbalance of YIN and YANG, deficiency of both the liver and kidney, the retardance of insufficiency of the spleen damp and hot, kidney network, toxin store up cause the symptom such as acute, chronic nephritis, renal failure.
The object of the invention is to provide a kind of herbal mixture oral liquid for the treatment of nephritis, it is characterized in that, be made up by ratio of weight and the number of copies of following medicine:
Radix Et Rhizoma Rhei 15 ~ 25kg, Cornu Cervi Pantotrichum 5 ~ 10kg, Semen Cuscutae 5 ~ 10kg, Herba clerodendranthi spicati 5 ~ 10kg, Flos persicae 15 ~ 25kg, Semen Litchi 5 ~ 10kg, Cortex Cinnamomi 15 ~ 20kg, Fructus Lycii 10 ~ 30kg, Rhizoma Zingiberis Recens 5 ~ 10kg, Herba Plantaginis 5 ~ 15kg, Poria 5 ~ 15kg, Tremella 10 ~ 25kg, common knotgrass 5 ~ 15kg, Radix Morindae Officinalis 5 ~ 10kg, Flos Lonicerae 15 ~ 25kg, Pericarpium Lagenariae sicerariae 5 ~ 10kg, Lignum Sappan 10 ~ 25kg, Cortex Moutan 5 ~ 15kg, Rhizoma Dioscoreae 5 ~ 15kg.
A kind of herbal mixture oral liquid for the treatment of nephritis of the present invention, its optimum ratio is:
Radix Et Rhizoma Rhei 20kg, Cornu Cervi Pantotrichum 8kg, Semen Cuscutae 10kg, Herba clerodendranthi spicati 8kg, Flos persicae 20kg, Semen Litchi 8kg, Cortex Cinnamomi 18kg, Fructus Lycii 20kg, Rhizoma Zingiberis Recens 8kg, Herba Plantaginis 10kg, Poria 10kg, the sub-18kg of Tremella, common knotgrass 10kg, Radix Morindae Officinalis 8kg, Flos Lonicerae 20kg, Pericarpium Lagenariae sicerariae 8kg, Lignum Sappan 18kg, Cortex Moutan 10kg, Rhizoma Dioscoreae 10kg.
A kind of preparation method for the treatment of the herbal mixture oral liquid of nephritis of the present invention, comprises the following steps:
Get Cornu Cervi Pantotrichum, after Herba clerodendranthi spicati, Flos persicae, Cortex Cinnamomi be ground into coarse powder in medicinal pulverizer, add 5 times amount 60% soak with ethanol about 40 minutes, heating and refluxing extraction 3 times; each 2 hours, merge extractive liquid, filtered; filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; After Semen Cuscutae, Semen Litchi, common knotgrass are ground into coarse powder in medicinal pulverizer, add 75% soak with ethanol about 40 minutes of 8 times amount, heating and refluxing extraction 3 times, each 2 hours, merge extractive liquid, filtered, filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; Radix Morindae Officinalis, after Herba Plantaginis is ground into coarse powder in medicinal pulverizer, adds 90% soak with ethanol about 40 minutes of 10 times amount, heating and refluxing extraction 3 times, each 2 hours, merge extractive liquid, filter, filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; After all the other Chinese medicines such as Radix Et Rhizoma Rhei are ground into coarse powder in medicinal pulverizer, the medicinal residues such as the Cornu Cervi Pantotrichum after extracting with different concentration ethanol, Semen Cuscutae, Radix Morindae Officinalis mix, add 10 times amount water soakings and be about 1h, decoct 3 times, each 2 hours, collecting decoction, and mix from the lixiviating solution of above-mentioned different determining alcohol, thin up is also stirred to dissolving, after room temperature leaves standstill about 24 hours, filter 23, after filtrate adds correctives antiseptic stirring and dissolving mix homogeneously, sterilizing in high steam pot, is finally distributed into (10ml/ props up) in oral liquid bottle.
Under option should meet " 2010 editions Chinese Pharmacopoeias " liquid preparation item.
[specification]: often prop up dress 10ml
[usage and dosage]:oral.One time 10ml(1 props up), three times on the one.
[indication]:be applicable to insufficiency of primordial QI, deficiency of YIN insufficiency of blood, imbalance of YIN and YANG, deficiency of both the liver and kidney, the retardance of insufficiency of the spleen damp and hot, kidney network, toxin store up cause the symptom such as acute, chronic nephritis, renal failure.
pharmacological property of the present invention is as follows:
Cornu Cervi Pantotrichum, controls weakness with emaciation, kidney-Yang invigorating, bone and muscle strengthening, removing blood stasis with potent drugs blood, fills blood, subsides a swelling bitterly, carries essence and blood; Herba clerodendranthi spicati, dispersing swelling and dissipating binds, the repercussive that detoxifies, sterilize anticancer; Flos persicae, blood circulation promoting and blood stasis dispelling, dredging the meridian, moisturizes laxation, detumescencing diuresis, the pleasant effect of relieving constipation; Cortex Cinnamomi, the kidney warming cold relieving, benefit fire supporing yang, the strengthening the spleen that nourishes blood, mind tranquilizing and the heart calming, vital energy regualting and blood circulation-promoting, promoting blood circulation, cure mainly spleen-kidney vacuity cold, dysuria, insufficiency of kidney-YANG; Semen Cuscutae has effect of nourishing the liver to improve visual acuity, the kidney invigorating and essence nourishing, invigorating the spleen to arrest diarrhea, analgesic antiphlogistic tonifying both YIN and YANG, for soreness of the waist and knees, suffers from a deficiency of the kidney, tinnitus, frequent micturition, has loose bowels, quenches one's thirst; Semen Litchi, cold relieving, eliminating stagnation, pain relieving, regulate the flow of vital energy, resolving depression; Common knotgrass, relieving stranguria by diuresis, killing parasites for relieving itching, antibacterial; Radix Morindae Officinalis, blood-supplementing blood-nourishing, warming the kidney to activate YANG, damp eliminating cold expelling, blood pressure lowering, antiinflammatory, resisting fatigue; Herba Plantaginis, heat clearing away, diuresis, subsides a swelling, eliminates the phlegm, detoxifies; Radix Et Rhizoma Rhei, relieving dyspepsia in eliminating blood stasis and inducing menstruation, removing stasis to stop bleeding, purging heat to relax the bowels, tune; Fructus Lycii, nourishing the liver, nourishing kidney, spermatogenesis, calm the nerves, be healthy and strong, blood pressure lowering; Rhizoma Zingiberis Recens, the cold expelling that activates yang, relieving the exterior syndrome by diaphoresis, antalgic, yang invigorating the kidney invigorating; Poria, promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, tranquilizing the mind, blood pressure lowering, blood sugar lowering; Tremella, essence strengthening and the kidney invigorating, replenishing YIN and removing heat, heat clearing away spleen invigorating, improve the body and culature, benefiting blood and regulating blood circulation, QI invigorating bowel relieving and promote immunologic function; Flos Lonicerae, enhancing human body immunity function, heat-clearing and toxic substances removing, detumescence dissipating blood stasis, dispelling wind to relieve the exterior syndrome and more widely antibacterial action; Pericarpium Lagenariae sicerariae, consumer edema, dredging water passages, eliminate the phlegm long-pending, control stranguria caused by urinary stone, control heat in the heart; Lignum Sappan, promoting the circulation of blood removing blood stasis with potent drugs, subduing swelling and relieving pain; Cortex Moutan, nourishing YIN to lower pathogenic fire, antipyretic-antalgic, promoting blood circulation to remove blood stasis, anti-inflammation, blood pressure lowering; Rhizoma Dioscoreae, body-building, spleen invigorating tonify deficiency, nourishing YIN and invigorating YANG, the mind calming and mentality promoting, slow down aging, replenishing essence is reinforced the kidney, invigorating the spleen and replenishing QI and the sanguimotor effect of improvement.The present invention is that compatibility worked in coordination with by Appropriate application medicine, the mutual reinforcement between mutual-assistance according to theory of Chinese medical science basis, jointly plays strengthening spleen, tonifying kidney, effect that promoting blood flow to regulate menstruation, replenishing essence are reinforced the kidney.
good effect of the present invention is:the present invention adopts natural Chinese medicinal herb, safe and effective, without incompatibility, have no drug resistance, have no side effect, have QI invigorating YIN nourishing, nourish blood strengthening the spleen, tranquilizing the mind, nourishing the liver lung moistening, effect of warming middle-JIAO YANG invigorating, be applicable to insufficiency of primordial QI, deficiency of YIN insufficiency of blood, imbalance of YIN and YANG, deficiency of both the liver and kidney, the retardance of insufficiency of the spleen damp and hot, kidney network, toxin store up cause the symptom such as acute, chronic nephritis, renal failure, treating both the principal and secondary aspects of a disease, Be very effective.In addition, oral formulations prepared by the present invention, adopts high temperature sterilize, and preparation technology is simple, can promote the use of, and utilizes xylitol, Cortex cinnamomi japonici (Ramulus Cinnamomi) syrup to cover the pained mouthfeel of Chinese medicine as correctives, improves patient's compliance.
detailed description of the invention:
For making the present invention easier to understand, below in conjunction with specific embodiment, set forth the present invention further.These embodiments are only not used in for illustration of the present invention and limit the scope of the invention.
embodiment 1:
prescription:radix Et Rhizoma Rhei 20kg, Cornu Cervi Pantotrichum 8kg, Semen Cuscutae 10kg, Herba clerodendranthi spicati 8kg, Flos persicae 20kg, Semen Litchi 8kg, Cortex Cinnamomi 18kg, Fructus Lycii 20kg, Rhizoma Zingiberis Recens 8kg, Herba Plantaginis 10kg, Poria 10kg, the sub-18kg of Tremella, common knotgrass 10kg, Radix Morindae Officinalis 8kg, Flos Lonicerae 20kg, Pericarpium Lagenariae sicerariae 8kg, Lignum Sappan 18kg, Cortex Moutan 10kg, Rhizoma Dioscoreae 10kg.
Get Cornu Cervi Pantotrichum, after Herba clerodendranthi spicati, Flos persicae, Cortex Cinnamomi be ground into coarse powder in medicinal pulverizer, add 5 times amount 60% soak with ethanol about 40 minutes, heating and refluxing extraction 3 times; each 2 hours, merge extractive liquid, filtered; filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; After Semen Cuscutae, Semen Litchi, common knotgrass are ground into coarse powder in medicinal pulverizer, add 75% soak with ethanol about 40 minutes of 8 times amount, heating and refluxing extraction 3 times; each 2 hours, merge extractive liquid, filtered; filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; Radix Morindae Officinalis, after Herba Plantaginis is ground into coarse powder in medicinal pulverizer, adds 90% soak with ethanol about 40 minutes of 10 times amount, heating and refluxing extraction 3 times, each 2 hours, merge extractive liquid, filter, filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%.After all the other Chinese medicines such as Radix Et Rhizoma Rhei are ground into coarse powder in medicinal pulverizer, Cornu Cervi Pantotrichum after extracting with different concentration ethanol, Semen Cuscutae, the medicinal residues mixing such as Radix Morindae Officinalis, add 10 times amount water soakings and be about 1h, decoct 3 times, each 2 hours, collecting decoction, and mix from the lixiviating solution of above-mentioned different determining alcohol, thin up is also stirred to dissolving, after room temperature leaves standstill about 24 hours, filter 23, filtrate adds correctives (250ml Cortex cinnamomi japonici (Ramulus Cinnamomi) syrup, 50mg saccharin sodium), antiseptic (10mg methyl hydroxybenzoate and propyl hydroxybenzoate 1:1), after stirring and dissolving mix homogeneously, sterilizing in high steam pot, finally be distributed into (10ml/ props up) in oral liquid bottle.
Under option should meet " 2010 editions Chinese Pharmacopoeias " liquid preparation item.
embodiment 2:
prescription:radix Et Rhizoma Rhei 15kg, Cornu Cervi Pantotrichum 5kg, Semen Cuscutae 5kg, Herba clerodendranthi spicati 5kg, 15 parts, Flos persicae, Semen Litchi 5kg, Cortex Cinnamomi 15kg, Fructus Lycii 10kg, Rhizoma Zingiberis Recens 5kg, Herba Plantaginis 5kg, Poria 5kg, the sub-10kg of Tremella, common knotgrass 5kg, Radix Morindae Officinalis 5kg, Flos Lonicerae 15kg, Pericarpium Lagenariae sicerariae 5kg, Lignum Sappan 10 parts, Cortex Moutan 5kg, Rhizoma Dioscoreae 5kg.
Get Cornu Cervi Pantotrichum, after Herba clerodendranthi spicati, Flos persicae, Cortex Cinnamomi be ground into coarse powder in medicinal pulverizer, add 5 times amount 60% soak with ethanol about 40 minutes, heating and refluxing extraction 3 times; each 2 hours, merge extractive liquid, filtered; filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; After Semen Cuscutae, Semen Litchi, common knotgrass are ground into coarse powder in medicinal pulverizer, add 75% soak with ethanol about 40 minutes of 8 times amount, heating and refluxing extraction 3 times; each 2 hours, merge extractive liquid, filtered; filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; Radix Morindae Officinalis, after Herba Plantaginis is ground into coarse powder in medicinal pulverizer, adds 90% soak with ethanol about 40 minutes of 10 times amount, heating and refluxing extraction 3 times, each 2 hours, merge extractive liquid, filter, filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%.After all the other Chinese medicines such as Radix Et Rhizoma Rhei are ground into coarse powder in medicinal pulverizer, Cornu Cervi Pantotrichum after extracting with different concentration ethanol, Semen Cuscutae, the medicinal residues mixing such as Radix Morindae Officinalis, add 10 times amount water soakings and be about 1h, decoct 3 times, each 2 hours, collecting decoction, and mix from the lixiviating solution of above-mentioned different determining alcohol, thin up is also stirred to dissolving, after room temperature leaves standstill about 24 hours, filter 23, filtrate adds correctives (250ml Cortex cinnamomi japonici (Ramulus Cinnamomi) syrup, 50mg saccharin sodium), antiseptic (10mg methyl hydroxybenzoate and propyl hydroxybenzoate 1:1), after stirring and dissolving mix homogeneously, sterilizing in high steam pot, finally be distributed into (10ml/ props up) in oral liquid bottle.
Under option should meet " 2010 editions Chinese Pharmacopoeias " liquid preparation item.
embodiment 3:
prescription:radix Et Rhizoma Rhei 25kg, Cornu Cervi Pantotrichum 10kg, Semen Cuscutae 10kg, Herba clerodendranthi spicati 10kg, Flos persicae 25kg, Semen Litchi 10kg, Cortex Cinnamomi 20kg, Fructus Lycii 30kg, Rhizoma Zingiberis Recens 10kg, Herba Plantaginis 15kg, Poria 15kg, the sub-25kg of Tremella, common knotgrass 15kg, Radix Morindae Officinalis 10kg, Flos Lonicerae 25kg, Pericarpium Lagenariae sicerariae 10kg, Lignum Sappan 25kg, Cortex Moutan 15kg, Rhizoma Dioscoreae 15kg.
Get Cornu Cervi Pantotrichum, after Herba clerodendranthi spicati, Flos persicae, Cortex Cinnamomi be ground into coarse powder in medicinal pulverizer, add 5 times amount 60% soak with ethanol about 40 minutes, heating and refluxing extraction 3 times; each 2 hours, merge extractive liquid, filtered; filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; After Semen Cuscutae, Semen Litchi, common knotgrass are ground into coarse powder in medicinal pulverizer, add 75% soak with ethanol about 40 minutes of 8 times amount, heating and refluxing extraction 3 times; each 2 hours, merge extractive liquid, filtered; filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; Radix Morindae Officinalis, after Herba Plantaginis is ground into coarse powder in medicinal pulverizer, adds 90% soak with ethanol about 40 minutes of 10 times amount, heating and refluxing extraction 3 times, each 2 hours, merge extractive liquid, filter, filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%.After all the other Chinese medicines such as Radix Et Rhizoma Rhei are ground into coarse powder in medicinal pulverizer, Cornu Cervi Pantotrichum after extracting with different concentration ethanol, Semen Cuscutae, the medicinal residues mixing such as Radix Morindae Officinalis, add 10 times amount water soakings and be about 1h, decoct 3 times, each 2 hours, collecting decoction, and mix from the lixiviating solution of above-mentioned different determining alcohol, thin up is also stirred to dissolving, after room temperature leaves standstill about 24 hours, filter 23, filtrate adds correctives (250ml Cortex cinnamomi japonici (Ramulus Cinnamomi) syrup, 50mg saccharin sodium), antiseptic (10mg methyl hydroxybenzoate and propyl hydroxybenzoate 1:1), after stirring and dissolving mix homogeneously, sterilizing in high steam pot, finally be distributed into (10ml/ props up) in oral liquid bottle.
Under option should meet " 2010 editions Chinese Pharmacopoeias " liquid preparation item.
medical effect of the present invention is proved by following experimental example:
Use Drug therapy nephritis patient of the present invention totally 50 example, wherein male 32 example, women 18 example, relate to age bracket be 32-68 year.According to the state of an illness, each serving with oral liquid 1 bottle, every day three times, early, middle and late oral, within two weeks, be a course for the treatment of, take one to two courses for the treatment of continuously, and observe therapeutic effect.The medicine identical with its effect is not taken at period in a medicine.
Model experiment example 1:
Close certain, female 45 years old, myasthenia of limbs, sore waist and aching in the waist and the back, all there is edema in lower limb, eyelid, face, inappetence, and usually Nausea and vomiting.After taking embodiment 1 obtained course for the treatment of of oral liquid continuously, eyelid, puffiness of face all fade away, extremity strong, lumbago alleviates, appetite is recovered all to some extent, and Nausea and vomiting phenomenon no longer occurs.
Model experiment example 2:
Wu, female 38 years old, lethargy, face is gloomy, and long-term appearance is tired out, lumbago and skelalgia, and urinate smooth, fear of cold is dizzy, myasthenia of limbs.After taking embodiment 2 obtained course for the treatment of of oral liquid continuously, spirit and mood all take a turn for the better, and extremity gradually effectively, also recover to some extent, and urine is also comparatively unobstructed, and sore waist and aching in the waist and the back symptom takes an evident turn for the better by muscle power.
Model experiment example 3:
Tang, man 46 years old, long term service pressure is large, and urine amount is gradually less, and headache is weak, and feel sick, edema phenomenon appears in two lower limb.After taking embodiment 3 obtained course for the treatment of of oral liquid continuously, extremity are gradually strong, and weak nauseating phenomenon disappears, and urine amount rises to some extent, and relieving constipation is also unobstructed before glue, and edema disappears.
Model experiment example 4:
Wang, man 52 years old, pulse condition is carefully heavy chaotic, green around the gills is without color, lassitude, lumbocrural pain, blood pressure can be in any more, and occur that hematuria phenomenon is after taking embodiment 1 obtained two courses for the treatment of of oral liquid continuously, spirit takes a turn for the better, and blood pressure recovers stable, of pink and healthy-looking, pulse condition recovers normal, and hematuria phenomenon also disappears.
Model experiment example 5:
Hu, man 36 years old, due to long-term work overlong time, and do not have a rest very well, occur anasarca, appetite weakens, and kidney is sent out, and the phenomenons such as sense that have an intense pain appear in waist, have a strong impact on orthobiosis.After taking embodiment 3 obtained two courses for the treatment of of oral liquid continuously, muscle power is recovered to some extent, and appetite also increases, and kidney portion pain disappears, and edema is also alleviated all to some extent.
Model experiment example 6:
Close certain, man 48 years old, insomnia, headache often occur shortness of breath and palpitation, it is not smooth just to have started one week urine, urine volume reduces gradually, and fear of cold is afraid of cold, sexual hypofunction, after taking embodiment 2 obtained course for the treatment of of oral liquid continuously, the mental status is good; urine is smooth and easy and normal, and urine volume also increases to some extent, and shortness of breath and palpitation and the cold fear of cold phenomenon of fear also take a turn for the better to some extent.
Through 6 routine typical patient clinical verifications, the herbal mixture oral formulations of this treatment nephritis, there is QI invigorating YIN nourishing, nourish blood strengthening the spleen, tranquilizing the mind, nourishing the liver lung moistening, effect of warming middle-JIAO YANG invigorating, be applicable to insufficiency of primordial QI, deficiency of YIN insufficiency of blood, imbalance of YIN and YANG, deficiency of both the liver and kidney, the retardance of insufficiency of the spleen damp and hot, kidney network, toxin store up cause the symptom such as acute, chronic nephritis, renal failure, treating both the principal and secondary aspects of a disease, Be very effective.In addition, oral formulations prepared by the present invention, adopts high temperature sterilize, and preparation technology is simple, can promote the use of, and utilizes xylitol, Cortex cinnamomi japonici (Ramulus Cinnamomi) syrup to cover the pained mouthfeel of Chinese medicine as correctives, improves patient's compliance.
Claims (3)
1. treat a herbal mixture oral liquid for nephritis, it is characterized in that being made up by ratio of weight and the number of copies of following medicine:
Radix Et Rhizoma Rhei 15 ~ 25, Cornu Cervi Pantotrichum 5 ~ 10, Semen Cuscutae 5 ~ 10, Herba clerodendranthi spicati 5 ~ 10, Flos persicae 15 ~ 25, Semen Litchi 5 ~ 10, Cortex Cinnamomi 15 ~ 20, Fructus Lycii 10 ~ 30, Rhizoma Zingiberis Recens 5 ~ 10, Herba Plantaginis 5 ~ 15, Poria 5 ~ 15, Tremella 10 ~ 25, common knotgrass 5 ~ 15, Radix Morindae Officinalis 5 ~ 10, Flos Lonicerae 15 ~ 25, Pericarpium Lagenariae sicerariae 5 ~ 10, Lignum Sappan 10 ~ 25, Cortex Moutan 5 ~ 15, Rhizoma Dioscoreae 5 ~ 15kg.
2. a kind of herbal mixture oral liquid for the treatment of nephritis according to claim 1, its optimum ratio is:
Radix Et Rhizoma Rhei 20, Cornu Cervi Pantotrichum 8, Semen Cuscutae 10, Herba clerodendranthi spicati 8, Flos persicae 20, Semen Litchi 8, Cortex Cinnamomi 18, Fructus Lycii 20, Rhizoma Zingiberis Recens 8, Herba Plantaginis 10, Poria 10, Tremella 18, common knotgrass 10, Radix Morindae Officinalis 8, Flos Lonicerae 20, Pericarpium Lagenariae sicerariae 8, Lignum Sappan 18, Cortex Moutan 10, Rhizoma Dioscoreae 10.
3. a kind of preparation method for the treatment of the herbal mixture oral liquid of nephritis described in claim 1 or 2, comprises the following steps:
Get Cornu Cervi Pantotrichum, after Herba clerodendranthi spicati, Flos persicae, Cortex Cinnamomi be ground into coarse powder in medicinal pulverizer, add 5 times amount 60% soak with ethanol about 40 minutes, heating and refluxing extraction 3 times, each 2 hours, merge extractive liquid, filtered, filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; After Semen Cuscutae, Semen Litchi, common knotgrass are ground into coarse powder in medicinal pulverizer, add 75% soak with ethanol about 40 minutes of 8 times amount, heating and refluxing extraction 3 times, each 2 hours, merge extractive liquid, filtered, filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; Radix Morindae Officinalis, after Herba Plantaginis is ground into coarse powder in medicinal pulverizer, adds 90% soak with ethanol 40 minutes of 10 times amount, heating and refluxing extraction 3 times, each 2 hours, merge extractive liquid, filter, filtrate is revolved to steam in evaporimeter in vacuum and is reclaimed ethanol, waves to ethanol content lower than 10%; After all the other Chinese medicines such as Radix Et Rhizoma Rhei are ground into coarse powder in medicinal pulverizer, the medicinal residues such as the Cornu Cervi Pantotrichum after extracting with different concentration ethanol, Semen Cuscutae, Radix Morindae Officinalis mix, add 10 times amount water soakings and be about 1h, decoct 3 times, each 2 hours, collecting decoction, and mix from the lixiviating solution of above-mentioned different determining alcohol, thin up is also stirred to dissolving, after room temperature leaves standstill about 24 hours, filter 23, after filtrate adds correctives, antiseptic stirring and dissolving mix homogeneously, sterilizing in high steam pot, is finally distributed in oral liquid bottle and get final product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728703A (en) * | 2017-03-09 | 2017-05-31 | 吉林大学珠海学院 | A kind of antifatigue, enhance immunity herbal mixture oral liquid and preparation method thereof |
| CN108771739A (en) * | 2018-09-04 | 2018-11-09 | 青岛市中心医院 | Application of acupuncture is combined at a kind of Chinese medicine composition that treating ephritis and acupuncture point |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106728703A (en) * | 2017-03-09 | 2017-05-31 | 吉林大学珠海学院 | A kind of antifatigue, enhance immunity herbal mixture oral liquid and preparation method thereof |
| CN108771739A (en) * | 2018-09-04 | 2018-11-09 | 青岛市中心医院 | Application of acupuncture is combined at a kind of Chinese medicine composition that treating ephritis and acupuncture point |
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| CN105106895B (en) | 2018-12-14 |
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