CN105232950A - Medicament for treating menstrual disorder and preparation method thereof - Google Patents

Medicament for treating menstrual disorder and preparation method thereof Download PDF

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CN105232950A
CN105232950A CN201510708235.0A CN201510708235A CN105232950A CN 105232950 A CN105232950 A CN 105232950A CN 201510708235 A CN201510708235 A CN 201510708235A CN 105232950 A CN105232950 A CN 105232950A
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parts
medicine
radix
medicament
menoxenia
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钟春明
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Abstract

The invention relates to a medicament for treating menstrual disorder and a preparation method thereof, and belongs to the field of a traditional Chinese medicine technology. The medicament is prepared by the following raw materials in parts by weight: 10-30 parts of cowherb seed, 8-15 parts of safflower, 5-10 parts of turtle shell glue, 8-16 parts of cooked rehmannia root, 5-10 parts of longan pulp, 5-15 parts of changium root, 10-15 parts of fragrant solomonseal rhizome, 5-15 parts of rhodiola root, 8-16 parts of astragali root and 10-20 parts of cyperus root. The manufacturing method comprises the following steps: selecting the materials, removing impurities, washing, carrying out two times of aqueous extractions in order, mixing extracts, carrying out a condensation, a drying and a pulverizing to obtain fine powder, tinning, and producing capsules. The medicament has a mild drug property for nursing and relieving, and is used for treating menstrual disorder thoroughly; the curative effect is substantial, and after cure, relapse is not easy to appear. The medicament is easy to dose, and is safe and reliable; the medicament does not have any side-effects.

Description

A kind of medicine for the treatment of menoxenia and preparation method thereof
[technical field]
The present invention relates to technical field of Chinese medicines, especially a kind of medicine for the treatment of menoxenia and preparation method thereof.
[technical background]
Menoxenia also claims menoxenia, it is a kind of common gynecological disease, show as menstrual cycle or amount of bleeding exception, or the moon is premenstrual, menstrual period time stomachache and General Symptoms, some women also with a series of abnormal sign such as spirit understanding anxiety, emotional instability, absent minded, irritable, depression, insomnia, headache, distending pain of the breast, has a strong impact on their routine work, studying and living at premenstrua.The cause of disease of menoxenia may be organic disease or malfunction.Many systemic diseases such as hematopathy, hypertension, hepatopathy, endocrinopathy, miscarriage, ectopic pregnancy, hydatidiform mole, reproductive tract infection, tumor (as ovarian tumor, hysteromyoma) etc. all can cause menoxenia.Menoxenia is divided into QIXUELIANGXU type, blood-cold type, blood-heat type, qi stagnation and blood stasis type, renal deficiency type etc. by the traditional Chinese medical science.Traditional Chinese Medicine according to the basic blood deficiency of menoxenia, suffer from a deficiency of the kidney, cold in blood, endocrine disturbance, emphasize that body is nursed one's health.Current clinical treatment dysmenorrhea, is with Western medicine analgesic or hormone medicine substantially, there is the defect that weak curative effect, easily recurrence and side effect are large.And treat the Chinese medicine of this type of disease, curative effect is all not satisfactory, cannot meet patient demand.
[summary of the invention]
In view of problem set forth above, the invention provides a kind of medicine for the treatment of menoxenia and preparation method thereof, the described medicine property of medicine is gentle, and conditioning is releived, be used for the treatment of menoxenia evident in efficacy, thorough treatment, not easily recur after healing, and medication is simple, safe and reliable, without any side effects.
Technical scheme of the present invention is as follows:
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 10-30 part, Flos Carthami 8-15 part, Colla carapax Trionycis 5-10 part, Radix Rehmanniae Preparata 8-16 part, Arillus Longan 5-10 part, Radix Changii 5-15 part, Rhizoma Polygonati Odorati 10-15 part, Radix Rhodiolae 5-15 part, Radix Astragali 8-16 part, Rhizoma Cyperi 10-20 part.
Further, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 15-25 part, Flos Carthami 10-14 part, Colla carapax Trionycis 7-9 part, Radix Rehmanniae Preparata 10-14 part, Arillus Longan 7-9 part, Radix Changii 8-12 part, Rhizoma Polygonati Odorati 12-14 part, Radix Rhodiolae 8-12 part, Radix Astragali 10-14 part, Rhizoma Cyperi 13-17 part.
Further, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 20 parts, 12 parts, Flos Carthami, Colla carapax Trionycis 8 parts, 12 parts, Radix Rehmanniae Preparata, Arillus Longan 8 parts, Radix Changii 10 parts, Rhizoma Polygonati Odorati 13 parts, Radix Rhodiolae 10 parts, the Radix Astragali 12 parts, Rhizoma Cyperi 15 parts.
Further, the preparation method of described medicine is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning with clear water, add 6-10 times of water soaking 20-30 minute, then decoct 40-60 minute, carry out first time to extract, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 3-8 times of soak by water 20-40 minute again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 80-100 eye mesh screen and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
Using method: for oral administration, three times on the one, early, middle and late half an hour ante cibum takes, each 3-4 grain, 2 months is a course for the treatment of.
Chinese medicine details in the present invention is as follows:
Semen Vaccariae: bitter in the mouth, property is put down, and returns liver, stomach warp.There is effect of promoting blood circulation to restore menstrual flow, stimulating milk secretion detumescence, inducing diuresis for treating stranguria syndrome, swell and ache for blood stasis amenorrhea, dysmenorrhea, agalactia, acute mastitis, the puckery pain of stranguria.
Flos Carthami: acrid in the mouth, warm in nature, GUIXIN, Liver Channel.There is effect of promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, swell and ache for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection.
Colla carapax Trionycis: salty in the mouth, micro-sweet, cold nature, returns lung, liver, kidney channel.There is nourishing YIN and supplementing blood, eliminating stasis and resolving masses, the kidney invigorating, the effect of bringing down a fever, cure mainly osteopyrexia and fever, chronic consumptive disease hemoptysis, malaria mass in the abdomen, blood deficiency amenorrhea, multiple abscess caused by damp-phlegm.
Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature, returns liver, kidney channel.There is effect of YIN nourishing of enriching blood, life essence-filling, marrow-benefitting, can be used for the diseases such as blood deficiency and yellow complexion, dizzy, palpitation and insomnia, menoxenia, metrorrhagia, diseases such as also can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, pass out semen, quench one's thirst.
Arillus Longan: sweet in the mouth, warm in nature, enter the heart, spleen channel.There is the effects such as invigorating the heart and spleen, nourishing blood to tranquillize the mind, invigorating the spleen to arrest diarrhea, inducing diuresis to remove edema, can be used for body void, insufficiency of vital energy and blood, severe palpitation, forgetful insomnia, blood deficiency and yellow complexion after being ill.
Radix Changii: sweet in the mouth, micro-hardship, cold nature, returns lung, stomach, Liver Channel.There is invigorating the spleen and replenishing QI, stomach function regulating nourish blood, the effect such as moistening the lung and resolving phlegm and removing toxic substances, fatigue and weakness usually, lassitude should be used for, consciously breathe hard, the slightly movable deficiency of vital energy patient with regard to dyspnea with rapid and short breath, and QI and blood deficiency pale complexion, feel dizzy, have no appetite, defecate rare patient soft, easy to catch cold.
Rhizoma Polygonati Odorati: sweet in the mouth, property is put down, and attaches to the lung and stomach meridians.There is effect of nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid.Can be used for the dry throat and mouth of cough caused by dryness, chronic cough, calentura cloudy liquid consumption wound, and interior-heat is quenched one's thirst, deficiency of YIN diseases caused by exogenous pathogenic factor, dizzy dizzy, muscle arteries and veins spasm and pain.
Radix Rhodiolae: property is sweet, bitter, taste is put down, and returns lung, heart channel.There is benefiting QI for activating blood circulation, promote blood circulation relieving asthma, detumescence is become silted up in improving water flood, anti-cerebral anoxia, resisting fatigue, clearing away lung-heat to relieve cough, change, antipyreticly bring down a fever, nourish the effects such as vigour.For blood stasis due to qi deficiency, obstruction of qi in the chest and cardialgia, apoplectic hemiplegia, asthenia is panted.
The Radix Astragali: sweet in the mouth, slightly warm in nature, returns lung, spleen, liver, kidney channel.There is effect of invigorating the spleen and replenishing QI, consolidating superficial resistance arresting sweating, holder skin ulcer granulation promoting, inducing diuresis to remove edema, can be used for that the treatment deficiency of vital energy is weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty are burst, burst for a long time do not hold back, blood deficiency and yellow complexion, interior-heat are quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.、
Rhizoma Cyperi: acrid in the mouth, sweet, micro-hardship, property is put down, and enters liver, tri-jiao channel.There is effect of resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, menoxenia, amenorrhea dysmenorrhea, colic of cold type is suffered from abdominal pain, distending pain of the breast.
The invention provides a kind of medicine for the treatment of menoxenia and preparation method thereof, compared with prior art, there is following beneficial effect: the medicine for the treatment of menoxenia provided by the present invention, according to the theory of traditional Chinese medical science the body resistance strengthening and constitution consolidating, nourishing YIN and supplementing blood, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to alleviate the stagnation in middle-JIAO, menstruction regulating and pain relieving, develops meticulously.There is promoting blood circulation to restore menstrual flow, blood stasis dispelling, detumescence, the Semen Vaccariae of analgesic efficacy, Flos Carthami for principal agent in side, with the Colla carapax Trionycis of nourishing YIN and supplementing blood, eliminating stasis and resolving masses, life essence-filling, marrow-benefitting, spleen-benefiting mind-tranquilizing, Radix Rehmanniae Preparata, Arillus Longan for accessory drugs, assistant is with Radix Changii, Rhizoma Polygonati Odorati, Radix Rhodiolae, the Radix Astragali and Rhizoma Cyperi and above all medicine compatibilities, nourishing YIN and clearing away heat, invigorating the spleen and replenishing QI, depressed liver-energy dispersing and QI regulating, blood stasis dispersing and deswelling, thus the effect reaching overall regulating menstruation.The present invention adopts above all medicine compatibilities, bring out the best in each other, play the merit of the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, nourishing YIN and clearing away heat, regulating QI to relieve pain altogether, the property of medicine is gentle, and conditioning is releived, treatment menoxenia Be very effective, thorough treatment, not easily recurs after healing, and medication is simple, safe and reliable, without any side effects.
[detailed description of the invention]
The following examples can help those skilled in the art more fully to understand the present invention, but cannot limit the present invention by any way.
Embodiment 1
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 10 parts, 8 parts, Flos Carthami, Colla carapax Trionycis 5 parts, 8 parts, Radix Rehmanniae Preparata, Arillus Longan 5 parts, Radix Changii 5 parts, Rhizoma Polygonati Odorati 10 parts, Radix Rhodiolae 5 parts, the Radix Astragali 8 parts, Rhizoma Cyperi 10 parts.Its preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning, adds 6 times of water soakings 20 minutes, then decocts 40 minutes with clear water, carries out first time and extracts, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 3 times of soak by water 20 minutes again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 100 eye mesh screens and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
Embodiment 2
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 15 parts, 10 parts, Flos Carthami, Colla carapax Trionycis 7 parts, 10 parts, Radix Rehmanniae Preparata, Arillus Longan 7 parts, Radix Changii 8 parts, Rhizoma Polygonati Odorati 12 parts, Radix Rhodiolae 8 parts, the Radix Astragali 10 parts, Rhizoma Cyperi 13 parts.Its preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning, adds 7 times of water soakings 20 minutes, then decocts 45 minutes with clear water, carries out first time and extracts, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 5 times of soak by water 25 minutes again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 100 eye mesh screens and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
Embodiment 3
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 20 parts, 12 parts, Flos Carthami, Colla carapax Trionycis 8 parts, 12 parts, Radix Rehmanniae Preparata, Arillus Longan 8 parts, Radix Changii 10 parts, Rhizoma Polygonati Odorati 13 parts, Radix Rhodiolae 10 parts, the Radix Astragali 12 parts, Rhizoma Cyperi 15 parts.Its preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning, adds 8 times of water soakings 25 minutes, then decocts 50 minutes with clear water, carries out first time and extracts, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 6 times of soak by water 30 minutes again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 90 eye mesh screens and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
Embodiment 4
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 25 parts, 14 parts, Flos Carthami, Colla carapax Trionycis 9 parts, 14 parts, Radix Rehmanniae Preparata, Arillus Longan 9 parts, Radix Changii 12 parts, Rhizoma Polygonati Odorati 14 parts, Radix Rhodiolae 12 parts, the Radix Astragali 14 parts, Rhizoma Cyperi 17 parts.Its preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning, adds 9 times of water soakings 30 minutes, then decocts 55 minutes with clear water, carries out first time and extracts, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 7 times of soak by water 35 minutes again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 80 eye mesh screens and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
Embodiment 5
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 30 parts, 15 parts, Flos Carthami, Colla carapax Trionycis 10 parts, 16 parts, Radix Rehmanniae Preparata, Arillus Longan 10 parts, Radix Changii 15 parts, Rhizoma Polygonati Odorati 15 parts, Radix Rhodiolae 15 parts, the Radix Astragali 16 parts, Rhizoma Cyperi 20 parts.Its preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning, adds 10 times of water soakings 30 minutes, then decocts 60 minutes with clear water, carries out first time and extracts, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 8 times of soak by water 40 minutes again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 80 eye mesh screens and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
The medicine of the obtained treatment menoxenia of embodiment 1 to embodiment 5, the property of medicine is gentle, and conditioning is releived, and treatment menoxenia Be very effective, thorough treatment, not easily recurs after healing, and medication is simple, safe and reliable, without any side effects.
Clinical observation is studied:
1, the object of observation: the present invention for traditional Chinese medical science menoxenia, through 100 routine clinical observations.Select tcm diagnosis menoxenia to be standard: young and middle-aged women menstruation is made a return journey irregular, excessive or too small through measuring, menstrual period overlong time so that anemia etc.As above symptom, can make a definite diagnosis.In the object making a definite diagnosis observation, be all women, without other serious diseases, the age is 17-45 year, 27.4 years old mean age.
2, instructions of taking: for oral administration, three times on the one, early, middle and late half an hour ante cibum takes, each 3-4 grain, 2 months is a course for the treatment of.Period in a medicine withdraws other drug and health nutrient, and avoid eating anything raw or cold, the thing of pungent, stimulation.
3, criterion of therapeutical effect:
Cure: menstrual cycle recovers normal, rule of making a return journey, general about 28 days, normal through measuring, menstrual period are moderate, and general about 4 days, the symptoms such as anemia were obviously alleviated.
Effective: menstrual cycle and through amount etc. make moderate progress.
Invalid: symptom has no improvement.
4, therapeutic effect:
Take medicine of the present invention 2 months after (course for the treatment of), observation draws: in the 100 routine objects of observation, cures 87 examples, effective 13 examples, total effective rate 100%.
Although above the present invention is described in detail with a general description of the specific embodiments, on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.

Claims (4)

1. treat a medicine for menoxenia, it is characterized in that described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 10-30 part, Flos Carthami 8-15 part, Colla carapax Trionycis 5-10 part, Radix Rehmanniae Preparata 8-16 part, Arillus Longan 5-10 part, Radix Changii 5-15 part, Rhizoma Polygonati Odorati 10-15 part, Radix Rhodiolae 5-15 part, Radix Astragali 8-16 part, Rhizoma Cyperi 10-20 part.
2. the medicine for the treatment of menoxenia according to claim 1, is characterized in that described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 15-25 part, Flos Carthami 10-14 part, Colla carapax Trionycis 7-9 part, Radix Rehmanniae Preparata 10-14 part, Arillus Longan 7-9 part, Radix Changii 8-12 part, Rhizoma Polygonati Odorati 12-14 part, Radix Rhodiolae 8-12 part, Radix Astragali 10-14 part, Rhizoma Cyperi 13-17 part.
3. the medicine for the treatment of menoxenia according to claim 2, is characterized in that described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 20 parts, 12 parts, Flos Carthami, Colla carapax Trionycis 8 parts, 12 parts, Radix Rehmanniae Preparata, Arillus Longan 8 parts, Radix Changii 10 parts, Rhizoma Polygonati Odorati 13 parts, Radix Rhodiolae 10 parts, the Radix Astragali 12 parts, Rhizoma Cyperi 15 parts.
4. according to the preparation method of the medicine of the arbitrary described treatment menoxenia of claim 1-3, it is characterized in that described preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning with clear water, add 6-10 times of water soaking 20-30 minute, decoct 40-60 minute again, carry out first time and extract, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 3-8 times of soak by water 20-40 minute again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 80-100 eye mesh screen and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
CN201510708235.0A 2015-10-27 2015-10-27 Medicament for treating menstrual disorder and preparation method thereof Pending CN105232950A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1095610A (en) * 1993-05-24 1994-11-30 潘世庆 The pharmaceutical preparation Fubingkang of treatment, prevention gynecological diseases
CN101513479A (en) * 2008-02-22 2009-08-26 北京天科仁祥医药科技有限公司 Chinese medicinal capsule with efficacies in regulating menstruation and removing spots, and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1095610A (en) * 1993-05-24 1994-11-30 潘世庆 The pharmaceutical preparation Fubingkang of treatment, prevention gynecological diseases
CN101513479A (en) * 2008-02-22 2009-08-26 北京天科仁祥医药科技有限公司 Chinese medicinal capsule with efficacies in regulating menstruation and removing spots, and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
薛晓鸥等: "四物汤治疗月经不调研究进展", 《北京中医药》 *

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