CN105232701A - Medicament for treating menstrual disorder and preparation method thereof - Google Patents
Medicament for treating menstrual disorder and preparation method thereof Download PDFInfo
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- CN105232701A CN105232701A CN201510708266.6A CN201510708266A CN105232701A CN 105232701 A CN105232701 A CN 105232701A CN 201510708266 A CN201510708266 A CN 201510708266A CN 105232701 A CN105232701 A CN 105232701A
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Abstract
The invention relates to a medicament for treating menstrual disorder and a preparation method thereof, and belongs to the field of a traditional Chinese medicine technology. The medicament is prepared by the following raw materials in parts by weight: 10-30 parts of cowherb seed, 10-20 parts of China rose, 5-10 parts of turtle shell glue, 8-16 parts of Chinese angelica, 5-10 parts of tuber fleece-flower root, 5-15 parts of changium root, 10-20 parts of ligustrum fruit, 5-15 parts of rhodiola root, 5-15 parts of acanthopanax root and 10-15 parts of sour orange flower. The manufacturing method comprises the following steps: selecting the materials, removing impurities, washing the materials, carrying out aqueous extraction twice in order, mixing extracts, carrying out condensation, drying and pulverizing of the mixture to obtain fine powder, tinning the fine powder, and producing capsules from the fine powder. The medicament has a mild drug property for nursing and relieving, and has such significant efficacy in treating menstrual disorder that the menstrual disorder can be cured thoroughly; the curative effect is substantial, and after cure, relapse is not easy to appear. The medicament is easy to dose, and is safe and reliable; the medicament does not have any side-effects.
Description
[technical field]
The present invention relates to technical field of Chinese medicines, especially a kind of medicine for the treatment of menoxenia and preparation method thereof.
[technical background]
Menoxenia also claims menoxenia, it is a kind of common gynecological disease, show as menstrual cycle or amount of bleeding exception, or the moon is premenstrual, menstrual period time stomachache and General Symptoms, some women also with a series of abnormal sign such as spirit understanding anxiety, emotional instability, absent minded, irritable, depression, insomnia, headache, distending pain of the breast, has a strong impact on their routine work, studying and living at premenstrua.The cause of disease of menoxenia may be organic disease or malfunction.Many systemic diseases such as hematopathy, hypertension, hepatopathy, endocrinopathy, miscarriage, ectopic pregnancy, hydatidiform mole, reproductive tract infection, tumor (as ovarian tumor, hysteromyoma) etc. all can cause menoxenia.Menoxenia is divided into QIXUELIANGXU type, blood-cold type, blood-heat type, qi stagnation and blood stasis type, renal deficiency type etc. by the traditional Chinese medical science.Traditional Chinese Medicine according to the basic blood deficiency of menoxenia, suffer from a deficiency of the kidney, cold in blood, endocrine disturbance, emphasize that body is nursed one's health.Current clinical treatment dysmenorrhea, is with Western medicine analgesic or hormone medicine substantially, there is the defect that weak curative effect, easily recurrence and side effect are large.And treat the Chinese medicine of this type of disease, curative effect is all not satisfactory, cannot meet patient demand.
[summary of the invention]
In view of problem set forth above, the invention provides a kind of medicine for the treatment of menoxenia and preparation method thereof, the described medicine property of medicine is gentle, and conditioning is releived, and is used for the treatment of menoxenia evident in efficacy, and thorough treatment is not easily recurred after healing; And medication is simple, safe and reliable, without any side effects.
Technical scheme of the present invention is as follows:
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 10-30 part, Flos Rosae Chinensis 10-20 part, Colla carapax Trionycis 5-10 part, Radix Angelicae Sinensis 8-16 part, Radix Polygoni Multiflori 5-10 part, Radix Changii 5-15 part, Fructus Ligustri Lucidi 10-20 part, Radix Rhodiolae 5-15 part, Radix Et Caulis Acanthopanacis Senticosi 5-15 part, Citrus aurantium L. var. amara Engl. 10-15 part.
Further, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 15-25 part, Flos Rosae Chinensis 13-17 part, Colla carapax Trionycis 7-9 part, Radix Angelicae Sinensis 10-14 part, Radix Polygoni Multiflori 7-9 part, Radix Changii 8-12 part, Fructus Ligustri Lucidi 13-17 part, Radix Rhodiolae 8-12 part, Radix Et Caulis Acanthopanacis Senticosi 8-12 part, Citrus aurantium L. var. amara Engl. 12-14 part.
Further, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 20 parts, Flos Rosae Chinensis 15 parts, Colla carapax Trionycis 8 parts, Radix Angelicae Sinensis 12 parts, Radix Polygoni Multiflori 8 parts, Radix Changii 10 parts, Fructus Ligustri Lucidi 15 parts, Radix Rhodiolae 10 parts, Radix Et Caulis Acanthopanacis Senticosi 10 parts, Citrus aurantium L. var. amara Engl. 13 parts.
Further, the preparation method of described medicine is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning with clear water, add 6-10 times of water soaking 20-30 minute, then decoct 40-60 minute, carry out first time to extract, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 3-8 times of soak by water 20-40 minute again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 80-100 eye mesh screen and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
Using method: for oral administration, three times on the one, early, middle and late half an hour ante cibum takes, each 3-4 grain, 2 months is a course for the treatment of.
Chinese medicine details in the present invention is as follows:
Semen Vaccariae: bitter in the mouth, property is put down, and returns liver, stomach warp.There is effect of promoting blood circulation to restore menstrual flow, stimulating milk secretion detumescence, inducing diuresis for treating stranguria syndrome, swell and ache for blood stasis amenorrhea, dysmenorrhea, agalactia, acute mastitis, the puckery pain of stranguria.
Flos Rosae Chinensis: sweet in the mouth, warm in nature, enter Liver Channel, there is effect of promoting blood flow to regulate menstruation, blood stasis dispelling circulation of qi promoting, subduing swelling and detoxicating, pain relieving.
Colla carapax Trionycis: salty in the mouth, micro-sweet, cold nature, returns lung, liver, kidney channel.There is nourishing YIN and supplementing blood, eliminating stasis and resolving masses, the kidney invigorating, the effect of bringing down a fever, cure mainly osteopyrexia and fever, chronic consumptive disease hemoptysis, malaria mass in the abdomen, blood deficiency amenorrhea, multiple abscess caused by damp-phlegm.
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature, returns liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, moisturize laxation, anticancer, anti-ageing anti-old, immune effect.Cure mainly that all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea, lump in the abdomen knot are poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine dyschezia, weight, ulcer sores, injury from falling down after bloody dysentery.
Radix Polygoni Multiflori: bitter in the mouth, sweet, puckery, slightly warm in nature, returns liver, kidney channel.There is enrich and benefit essence and blood, calm the nerves, active, invigorating the liver and kidney, bone and muscle strengthening, black beard and hair, removing toxic substances (preventing the attack (or recurrence) of malaria), eliminating carbuncle effect.For blood deficiency, Light-headedness, fatigue and asthenia, sallow, Liver and kidney blood and essence asthenia, vertigo and tinnitus, waist urushic acid are soft, early whitening of beard and hair, hyperlipidemia.
Radix Changii: sweet in the mouth, micro-hardship, cold nature, returns lung, stomach, Liver Channel.There is invigorating the spleen and replenishing QI, stomach function regulating nourish blood, the effect such as moistening the lung and resolving phlegm and removing toxic substances, fatigue and weakness usually, lassitude should be used for, consciously breathe hard, the slightly movable deficiency of vital energy patient with regard to dyspnea with rapid and short breath, and QI and blood deficiency pale complexion, feel dizzy, have no appetite, defecate rare patient soft, easy to catch cold.
Fructus Ligustri Lucidi: sweet in the mouth, hardship, cool in nature, return liver, kidney channel.There is effect of replenishing kidney-YIN, nourishing the liver to improve visual acuity, clearind deficient heat.Cure mainly: deficiency of the liver and kindey, to have a dizzy spell, early whitening of beard and hair, blurring of vision, fever due to yin deficiency.
Radix Rhodiolae: property is sweet, bitter, taste is put down, and returns lung, heart channel.There is benefiting QI for activating blood circulation, promote blood circulation relieving asthma, detumescence is become silted up in improving water flood, anti-cerebral anoxia, resisting fatigue, clearing away lung-heat to relieve cough, change, antipyreticly bring down a fever, nourish the effects such as vigour.For blood stasis due to qi deficiency, obstruction of qi in the chest and cardialgia, apoplectic hemiplegia, asthenia asthma.
Radix Et Caulis Acanthopanacis Senticosi: acrid in the mouth, hardship, micro-sweet, warm in nature, returns liver, kidney channel.There is replenishing QI to invigorate the spleen, invigorating middle warmer benefit essence, tonifying the kidney for tranquilization, blood circulation and promoting silt, stomach invigorating diuresis, wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, feeling pulse effect of invigorating blood circulation.Cure mainly that anemofrigid-damp arthralgia, spleen kidney yang deficiency, body void are weak, inappetence, lumbocrural pain, muscles and bones flaccidity are soft, be slow in action, insomnia and dreamful sleep, traumatic injury, fracture, edema, beriberi, uncontrolled urination itch.
Citrus aurantium L. var. amara Engl.: bitter in the mouth, acid, cold nature, has effect of promoting the circulation of QI to alleviate the stagnation in middle-JIAO, appetite-stimulating indigestion-relieving, the preventing or arresting vomiting that reduces phlegm, can be used for that breast gastral cavity painful abdominal mass is vexed, anorexia, nausea and vomiting, stomachache, stomachache.
The invention provides a kind of medicine for the treatment of menoxenia and preparation method thereof, compared with prior art, there is following beneficial effect: the medicine for the treatment of menoxenia provided by the present invention, according to the theory of traditional Chinese medical science the body resistance strengthening and constitution consolidating, nourishing YIN and supplementing blood, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to alleviate the stagnation in middle-JIAO, menstruction regulating and pain relieving, develops meticulously.There is promoting blood flow to regulate menstruation, blood stasis dispelling circulation of qi promoting, the Semen Vaccariae of reducing swelling and alleviating pain effect, Flos Rosae Chinensis for principal agent in side, with enrich and benefit essence and blood, actively to calm the nerves, the Colla carapax Trionycis of invigorating the liver and kidney, Radix Angelicae Sinensis, Radix Polygoni Multiflori be for accessory drugs, assistant is with Radix Changii, Fructus Ligustri Lucidi, Radix Rhodiolae, Radix Et Caulis Acanthopanacis Senticosi and Citrus aurantium L. var. amara Engl. and above all medicine compatibilities, enriching yin and nourishing kidney, invigorating middle warmer benefit essence, benefiting vital QI for tranquillizing, depressed liver-energy dispersing and QI regulating, heat-clearing and toxic substances removing, thus the effect reaching overall regulating menstruation.The present invention adopts above all medicine compatibilities, bring out the best in each other, play the merit of the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, nourishing YIN and clearing away heat, regulating QI to relieve pain altogether, the property of medicine is gentle, and conditioning is releived, treatment menoxenia Be very effective, thorough treatment, not easily recurs after healing, and medication is simple, safe and reliable, without any side effects.
[detailed description of the invention]
The following examples can help those skilled in the art more fully to understand the present invention, but cannot limit the present invention by any way.
Embodiment 1
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 10 parts, Flos Rosae Chinensis 10 parts, Colla carapax Trionycis 5 parts, Radix Angelicae Sinensis 8 parts, Radix Polygoni Multiflori 5 parts, Radix Changii 5 parts, Fructus Ligustri Lucidi 10 parts, Radix Rhodiolae 5 parts, Radix Et Caulis Acanthopanacis Senticosi 5 parts, Citrus aurantium L. var. amara Engl. 10 parts.Its preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning, adds 6 times of water soakings 20 minutes, then decocts 40 minutes with clear water, carries out first time and extracts, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 3 times of soak by water 20 minutes again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 100 eye mesh screens and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
Embodiment 2
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 15 parts, Flos Rosae Chinensis 13 parts, Colla carapax Trionycis 7 parts, Radix Angelicae Sinensis 10 parts, Radix Polygoni Multiflori 7 parts, Radix Changii 8 parts, Fructus Ligustri Lucidi 13 parts, Radix Rhodiolae 8 parts, Radix Et Caulis Acanthopanacis Senticosi 8 parts, Citrus aurantium L. var. amara Engl. 12 parts.Its preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning, adds 7 times of water soakings 20 minutes, then decocts 45 minutes with clear water, carries out first time and extracts, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 5 times of soak by water 25 minutes again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 100 eye mesh screens and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
Embodiment 3
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 20 parts, Flos Rosae Chinensis 15 parts, Colla carapax Trionycis 8 parts, Radix Angelicae Sinensis 12 parts, Radix Polygoni Multiflori 8 parts, Radix Changii 10 parts, Fructus Ligustri Lucidi 15 parts, Radix Rhodiolae 10 parts, Radix Et Caulis Acanthopanacis Senticosi 10 parts, Citrus aurantium L. var. amara Engl. 13 parts.Its preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning, adds 8 times of water soakings 25 minutes, then decocts 50 minutes with clear water, carries out first time and extracts, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 6 times of soak by water 30 minutes again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 90 eye mesh screens and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
Embodiment 4
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 25 parts, Flos Rosae Chinensis 17 parts, Colla carapax Trionycis 9 parts, Radix Angelicae Sinensis 14 parts, Radix Polygoni Multiflori 9 parts, Radix Changii 12 parts, Fructus Ligustri Lucidi 17 parts, Radix Rhodiolae 12 parts, Radix Et Caulis Acanthopanacis Senticosi 12 parts, Citrus aurantium L. var. amara Engl. 14 parts.Its preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning, adds 9 times of water soakings 30 minutes, then decocts 55 minutes with clear water, carries out first time and extracts, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 7 times of soak by water 35 minutes again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 80 eye mesh screens and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
Embodiment 5
Treat a medicine for menoxenia, described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 30 parts, Flos Rosae Chinensis 20 parts, Colla carapax Trionycis 10 parts, Radix Angelicae Sinensis 16 parts, Radix Polygoni Multiflori 10 parts, Radix Changii 15 parts, Fructus Ligustri Lucidi 20 parts, Radix Rhodiolae 15 parts, Radix Et Caulis Acanthopanacis Senticosi 15 parts, Citrus aurantium L. var. amara Engl. 15 parts.Its preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning, adds 10 times of water soakings 30 minutes, then decocts 60 minutes with clear water, carries out first time and extracts, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 8 times of soak by water 40 minutes again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 80 eye mesh screens and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
The medicine of the obtained treatment menoxenia of embodiment 1 to embodiment 5, the property of medicine is gentle, and conditioning is releived, and treatment menoxenia Be very effective, thorough treatment, not easily recurs after healing, and medication is simple, safe and reliable, without any side effects.
Clinical observation is studied:
1, the object of observation: the present invention for traditional Chinese medical science menoxenia, through 100 routine clinical observations.Select tcm diagnosis menoxenia to be standard: young and middle-aged women menstruation is made a return journey irregular, excessive or too small through measuring, menstrual period overlong time so that anemia etc.As above symptom, can make a definite diagnosis.In the object making a definite diagnosis observation, be all women, without other serious diseases, the age is 18-42 year, 26.5 years old mean age.
2, instructions of taking: for oral administration, three times on the one, early, middle and late half an hour ante cibum takes, each 3-4 grain, 2 months is a course for the treatment of.Period in a medicine withdraws other drug and health nutrient, and avoid eating anything raw or cold, the thing of pungent, stimulation.
3, criterion of therapeutical effect:
Cure: menstrual cycle recovers normal, rule of making a return journey, general about 28 days, normal through measuring, menstrual period are moderate, and general about 4 days, the symptoms such as anemia were obviously alleviated.
Effective: menstrual cycle and through amount etc. make moderate progress.
Invalid: symptom has no improvement.
4, therapeutic effect:
Take medicine of the present invention 2 months after (course for the treatment of), observation draws: in the 100 routine objects of observation, cures 85 examples, effective 15 examples, total effective rate 100%.
Although above the present invention is described in detail with a general description of the specific embodiments, on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.
Claims (4)
1. treat a medicine for menoxenia, it is characterized in that described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 10-30 part, Flos Rosae Chinensis 10-20 part, Colla carapax Trionycis 5-10 part, Radix Angelicae Sinensis 8-16 part, Radix Polygoni Multiflori 5-10 part, Radix Changii 5-15 part, Fructus Ligustri Lucidi 10-20 part, Radix Rhodiolae 5-15 part, Radix Et Caulis Acanthopanacis Senticosi 5-15 part, Citrus aurantium L. var. amara Engl. 10-15 part.
2. the medicine for the treatment of menoxenia according to claim 1, is characterized in that described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 15-25 part, Flos Rosae Chinensis 13-17 part, Colla carapax Trionycis 7-9 part, Radix Angelicae Sinensis 10-14 part, Radix Polygoni Multiflori 7-9 part, Radix Changii 8-12 part, Fructus Ligustri Lucidi 13-17 part, Radix Rhodiolae 8-12 part, Radix Et Caulis Acanthopanacis Senticosi 8-12 part, Citrus aurantium L. var. amara Engl. 12-14 part.
3. the medicine for the treatment of menoxenia according to claim 2, is characterized in that described medicine is prepared from by the raw material of following weight portion: Semen Vaccariae 20 parts, Flos Rosae Chinensis 15 parts, Colla carapax Trionycis 8 parts, Radix Angelicae Sinensis 12 parts, Radix Polygoni Multiflori 8 parts, Radix Changii 10 parts, Fructus Ligustri Lucidi 15 parts, Radix Rhodiolae 10 parts, Radix Et Caulis Acanthopanacis Senticosi 10 parts, Citrus aurantium L. var. amara Engl. 13 parts.
4. according to the preparation method of the medicine of the arbitrary described treatment menoxenia of claim 1-3, it is characterized in that described preparation method is: pick described raw material according to above-mentioned weight portion, removing impurity, after cleaning with clear water, add 6-10 times of water soaking 20-30 minute, decoct 40-60 minute again, carry out first time and extract, filter to obtain decoction liquor A and filtering residue A; In filtering residue, add 3-8 times of soak by water 20-40 minute again, carry out second time and extract, cross leaching decoction liquor B; Merge decoction liquor A and decoction liquor B, be condensed into thick paste, pulverize after bake drying, cross 80-100 eye mesh screen and obtain fine powder, mixing, tinning becomes capsule, and 0.5 gram every, get product medicine.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510708266.6A CN105232701A (en) | 2015-10-27 | 2015-10-27 | Medicament for treating menstrual disorder and preparation method thereof |
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| CN201510708266.6A CN105232701A (en) | 2015-10-27 | 2015-10-27 | Medicament for treating menstrual disorder and preparation method thereof |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101919933A (en) * | 2009-06-09 | 2010-12-22 | 罗会军 | Application of stonecrop spot removal tablet in preparing medicaments for treating emmeniopathies |
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2015
- 2015-10-27 CN CN201510708266.6A patent/CN105232701A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101919933A (en) * | 2009-06-09 | 2010-12-22 | 罗会军 | Application of stonecrop spot removal tablet in preparing medicaments for treating emmeniopathies |
Non-Patent Citations (1)
| Title |
|---|
| 申宝林: "中药人工周期治疗稀发月经和继发性闭经80例疗效观察", 《山西中医学院学报》 * |
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