CN105232810A - Traditional Chinese medicine for treating chalkstone - Google Patents
Traditional Chinese medicine for treating chalkstone Download PDFInfo
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- CN105232810A CN105232810A CN201510656537.8A CN201510656537A CN105232810A CN 105232810 A CN105232810 A CN 105232810A CN 201510656537 A CN201510656537 A CN 201510656537A CN 105232810 A CN105232810 A CN 105232810A
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Abstract
The invention relates to traditional Chinese medicine for treating chalkstone. The traditional Chinese medicine comprises, by weight, 10 parts of plumbago zeylanica, 9 parts of rubus buergeri, 25 parts of pandanus tectorius, 18 parts of thladiantha nudiflora, 8 parts of spring bittercress, 8 parts of polygonum perfoliatum, 20 parts of hibiscus rosa-sinensis and 12 parts of phyllanthus cochinchinensis. Clinical experiments prove that the chalkstone can be treated safely and effectively by the traditional Chinese medicine.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to one and be used for the treatment of tophaceous Chinese medicine.
Background technology
In the pathogenic process of gout patients, there will be a kind of rock-hard tuberosity, be called " tophus ", have another name called tophus.This Monosodium urate crystallization deposition, in soft tissue, causes the tophus that chronic inflammatory disease and proliferation of fibrous tissue are formed.Tophus is most commonly in helix, also Duo Jian Yu Hallux toe Metatarsophalangeal joint, refer to, the place such as wrist, elbow and knee joint, a few patients can appear at nasal cartilages, tongue, vocal cords, eyelid, aorta, cardiac valve and cardiac muscle.In the skeleton of juxtra-articular, invade sclerotin, form skeleton deformity, or sclerotin is damaged.This tophus also can find in the synovial bursa film of juxtra-articular, stndon sheath and cartilage.Tophus is not of uniform size, little of Semen Sesami, large as egg.
The traditional Chinese medical science: arthromyodynia, the red and swollen severe pain recurrent exerbation of Minor articulus such as primary disease is with big toe, metatarsophalangeal joints, instep, heel, ankle, refer to, wrist, joint deformity, forms the sick class disease of limbs numbness that " tophus " is main manifestations.
Medical material present Research involved in the present invention is as follows:
Radix Plumbaginis Zeylanicae [another name] hillside Siberian cocklebur, false jasmine, house steward, dry in and, bird face horse, white snowflake, wild lucerne jasmine, every cloth grass, thousand Semen Arecaes, according to medicine, sky Semen Arecae, white soap medicine, spend soap medicine in vain, see and disappear, spend Rhizoma Rodgersiae in vain, spend JIUGUNIU in vain, Yu Xiaohua, spend The Iron Buddha, fiery miracle, suddenly tiger in vain.[source] medical material Ji Yuan: be herb or the root of Plumbaginaceae plant Radix Plumbaginis Zeylanicae.Gather and store: the whole year all can adopt, cutting is dried or using fresh herb.[nature and flavor] are pungent; Bitter; Puckery; Property wets; [return through] GUIXIN warp, Liver Channel, spleen channel.[function cures mainly] expelling wind and removing dampness; Promoting flow of QI and blood; Removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome; Heart peratodynia; Hepatosplenomegaly; Blood stasis amenorrhea; Osteopatia sprain; Carbuncle scrofula; Scabies pruritus; Venom.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] anemia of pregnant woman prohibits clothes.[extracts] " China's book on Chinese herbal medicine ".
Herba rubi buergeri [source] to be trembled with fear the leaf of the certain kind of berries or herb for rosaceous plant.[nature and flavor] acid, flat, nontoxic.[return through] returns kidney channel.[function cures mainly] energy nourishing YIN benefit essence, as antasthenic.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] cold cough avoids use.[extracts] " China's book on Chinese herbal medicine ".
Radix Pandani Furcati [another name] wild Fructus Ananadis comosi, Radix Pandani Furcati, Luo Jindui.[source] is the root of the mould pocket tree of Pandanaceae plant bifurcated.The whole year can adopt.[nature and flavor] are sweet light, cool.[return through] returns kidney channel, Liver Channel, urinary bladder channel.[function cures mainly] clearing away heat and promoting diuresis, diaphoresis pain relieving.Cure cold heating, urinary tract infection, oedema due to nephritis, conjunctivitis, hepatitis, lumbago, skelalgia of rheumatism, colicky.[usage and dosage] takes orally: decoct soup, 50 ~ 100g.[extracts] " China's book on Chinese herbal medicine ".
South Fructus Thladianthae Dubiae [another name] wild Fructus Benincasae, ball lotus, Viola grypoceras A. Gray, Cortex Cannabis Fructus Trichosanthis, wild Fructus Trichosanthis, black melon, Fructus Momordicae charantiae beach wormwood, Qinling Mountains Fructus Thladianthae Dubiae, wild Fructus Luffae, Fructus Luffae south.[source] medical material Ji Yuan: be root or the leaf of cucurbitaceous plant south Fructus Thladianthae Dubiae.Gather and store: spring, picking leaves in summer, using fresh herb or dry.Adopt root, using fresh herb or section are dried after autumn.[nature and flavor] bitter in the mouth; Cool in nature.[return through] returns gastrointestinal warp.[function cures mainly] heat-clearing and toxic substances removing; Relieving dyspepsia.Main dysentery; Intestinal is scorching; Dyspepsia; Gastral cavity abdominal distention is vexed; Venom [usage and dosage] takes orally: decoct soup, 9 ~ 18g.[extracts] " China's book on Chinese herbal medicine ".
Impatient bittercress herb [another name] ottelia cordata, spray dish.[source] is the herb of crucifer impatient bittercress herb.Gather and store: spring gathers, using fresh herb or dry.[nature and flavor] are light; Flat.[return through] GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.[function cures mainly] promoting blood flow to regulate menstruation; Heat-clearing and toxic substances removing; Inducing diuresis for treating stranguria syndrome.Main menoxenia; Carbuncle; Stranguria.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Herba Polygoni cymosi [another name] Herba Lespedezae Cuneatae, colter thorn, river Pennisetum centrasiaticum Tzvel, ant grasshopper le, urgency are separated element, tiger Lei, ram's horn thorn, Herba Polygoni cymosi, She Yacao, are worn leaf knotweed.[source] passes through the herb of leaf knotweed for Polygonaceae arsesmart.Gather during summer fall planting strain riotous growth, dry.[nature and flavor] acid, cool.[return through] returns lung, gallbladder, spleen, large intestine, small intestine meridian.[function cures mainly] heat-clearing and toxic substances removing, inducing diuresis to remove edema.For upper respiratory tract infection, tracheitis, pertussis, acute tonsillitis, enteritis, dysentery, oedema due to nephritis; Herpes zoster is controlled in external, eczema, carbuncle furuncle and phyma poison, venom.[usage and dosage] takes orally: decoct soup, 3-9g.[extracts] " China's book on Chinese herbal medicine ".
Flos Hibisci Rosae-Sinensis [another name] is taken, Caulis et folium clerodendri bungei, hang spring Flos Carthami, Folium Lantanae Camarae, bright red Flos Moutan, fuchsia, wood flower, friend is red, cock is colored, Buddhist Flos Mori, crafty headdress flower, Skapanthus C.Y.Wu et H.W.Li,nom.nov., ZHUANGYUANHONG.[source] medical material Ji Yuan: be the flower of Malvaceae plant Hibiscus rosasinensis.Gather and store: plucking when spending half-open, dry.[nature and flavor] are sweet; Light; Flat.[return through] heart; Lung; Liver; Spleen channel.[function cures mainly] lung heat clearing; Removing heat from blood; Removing dampness; Removing toxic substances.Main cough due to lung-heat; Spitting of blood; Epistaxis; Metrorrhagia; Leucorrhea; Dysentery; Reddish and whitish turbid urine; Carbuncle skin infection.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Radix Phyllanthi cochinchinensis [another name] Cotton Gossypii, Herba anemones vitifoliae, wild Flos persicae, Polygonum runcinatum Buch.Ham, Five Dragons meeting, eight sledgehammers, black clouds lid snow.[source] Malvaceae Herba urenae procumbentis platymiscium Herba urenae procumbentis, is used as medicine with root and leaf.Autumn uproots, the picking leaves of autumn in summer, cleans chopping, dries.[nature and flavor] are sweet, bitter, flat.[return through] returns lung; Stomach two warp.[function cures mainly] expelling wind and removing dampness, heat-clearing and toxic substances removing.For flu, rheumatic arthritis, enteritis, dysentery, cough due to lung-heat; Traumatic injury is controlled in external, sore swollen toxin, venom.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide one and is used for the treatment of tophaceous Chinese medicine, by selecting suitable medical material and proportioning thereof, reaches the tophaceous object of safe and effective healing.
In order to achieve the above object, the present invention is by the following technical solutions:
One is used for the treatment of tophaceous Chinese medicine; it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Plumbaginis Zeylanicae 10 parts, Herba rubi buergeri 9 parts, Radix Pandani Furcati 25 parts, southern Fructus Thladianthae Dubiae 18 parts, impatient bittercress herb 8 parts, Herba Polygoni cymosi 8 parts, Flos Hibisci Rosae-Sinensis 20 parts, Radix Phyllanthi cochinchinensis 12 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and tophus patient 96 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 56 example and matched group 40 example at random, treatment group man 53 example, female 3 example, 20 ~ 69 years old age, 43.5 years old mean age; Matched group man 38 example, female 2 example, 20 ~ 69 years old age, 48 years old mean age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national tophus clinical speciality:
(1). the joint of recurrent exerbation is red, swollen, hot, bitterly, typical parts is sufficient metatarsophalangeal joints, and other comprises ankle, knee joint, wrist, elbow, metacarpophalangeal joints etc.Course of disease elder can have joint deformity, arthroedema, periarticular or auricle portion tophus to be formed, and can overflow white urate crystal, also can detect urate crystal in hydrarthrosis after calculus ulceration.Outbreak is often with General Symptomies such as fear of cold heating, headache, whole body discomforts.
(2). in being more common in, elderly men, overweight or overweight people is in the majority.
(3). blood uric acid is generally greater than 380 μm of ol/L(6.4mg/dl).
(4). urine uric acid discharge capacity increases, and easily form urate calculus and gouty nephropathy, course of disease person of a specified duration causes renal hypofunction.
(5). pathological changes joint x-ray takes the photograph rounded or irregular punched-out defect district, sheet visible joint face, and local sclerotin can have osteoporosis to change.Pyelography or B-type ultrasonography prompting renal calculus exist.
(6). skin symptom: the case of about 1/2, have urate deposition in subcutaneous, these tuberositys are called as tophus or tophus.Tophus often in white or pearl tuberosity (gout Margarita), betides the skin edge (as auricle) of free arc.The other characteristic symptom of tophus refers to (toe) joint white or yellow tuberosity.Skin urate deposition.Thunder egg is seen by thinning skin, and they may ulceration.The tophus of juxtra-articular has the trend occurring in groups or merge.Tophus produces after acute attack, painless.If skin ulceration, can discharge white Calx sample material, the carcinogenic mixture of microscopical examination showed pencil pin sample material, is accredited as Monosodium urate.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.2 weeks courses for the treatment of.
The oral colchicine of matched group, ibuprofen: 0.4g, every day 3 times; Naproxen, 250 ~ 350mg, every twice-daily.2 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Cure: clinical symptom disappearance, in blood and urine, uric acid content is normal, normal renal function, follows up a case by regular visits to more than 2 years continuously without recurrence.
Effective: in the situation of taking medicine, remission.In blood and urine, uric acid content is close to normal, and renal function takes a turn for the better.
Invalid: after treating 2 weeks, clinical symptoms is without change, and joint is red, swollen, hot, pain symptom is not obvious, and activity is still influenced, and Level of Serum Uric Acid does not decline.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
| Group | n | Cure | Effectively | Invalid | Total effective rate (%) | Serious adverse reaction example |
| Treatment group | 56 | 10 | 43 | 3 | 94.64% | 0 |
| Matched group | 40 | 5 | 25 | 10 | 75% | 0 |
Visible, the medicine that the present invention obtains can safe and effective treatment tophus, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Radix Plumbaginis Zeylanicae 10 grams, Herba rubi buergeri 9 grams, Radix Pandani Furcati 25 grams, southern Fructus Thladianthae Dubiae 18 grams, impatient bittercress herb 8 grams, Herba Polygoni cymosi 8 grams, Flos Hibisci Rosae-Sinensis 20 grams, Radix Phyllanthi cochinchinensis 12 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of tophus.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Radix Plumbaginis Zeylanicae 10 grams, Herba rubi buergeri 9 grams, Radix Pandani Furcati 25 grams, southern Fructus Thladianthae Dubiae 18 grams, impatient bittercress herb 8 grams, Herba Polygoni cymosi 8 grams, Flos Hibisci Rosae-Sinensis 20 grams, Radix Phyllanthi cochinchinensis 12 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of tophus.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Radix Plumbaginis Zeylanicae 10 grams, Herba rubi buergeri 9 grams, Radix Pandani Furcati 25 grams, southern Fructus Thladianthae Dubiae 18 grams, impatient bittercress herb 8 grams, Herba Polygoni cymosi 8 grams, Flos Hibisci Rosae-Sinensis 20 grams, Radix Phyllanthi cochinchinensis 12 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of tophus.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (4)
1. one kind is used for the treatment of tophaceous Chinese medicine; it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Plumbaginis Zeylanicae 10 parts, Herba rubi buergeri 9 parts, Radix Pandani Furcati 25 parts, southern Fructus Thladianthae Dubiae 18 parts, impatient bittercress herb 8 parts, Herba Polygoni cymosi 8 parts, Flos Hibisci Rosae-Sinensis 20 parts, Radix Phyllanthi cochinchinensis 12 parts.
2. be used for the treatment of tophaceous Chinese medicine as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix Plumbaginis Zeylanicae 10 parts, Herba rubi buergeri 9 parts, Radix Pandani Furcati 25 parts, southern Fructus Thladianthae Dubiae 18 parts, impatient bittercress herb 8 parts, Herba Polygoni cymosi 8 parts, Flos Hibisci Rosae-Sinensis 20 parts, Radix Phyllanthi cochinchinensis 12 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of tophaceous Chinese medicine as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix Plumbaginis Zeylanicae 10 parts, Herba rubi buergeri 9 parts, Radix Pandani Furcati 25 parts, southern Fructus Thladianthae Dubiae 18 parts, impatient bittercress herb 8 parts, Herba Polygoni cymosi 8 parts, Flos Hibisci Rosae-Sinensis 20 parts, Radix Phyllanthi cochinchinensis 12 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of tophaceous Chinese medicine as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix Plumbaginis Zeylanicae 10 parts, Herba rubi buergeri 9 parts, Radix Pandani Furcati 25 parts, southern Fructus Thladianthae Dubiae 18 parts, impatient bittercress herb 8 parts, Herba Polygoni cymosi 8 parts, Flos Hibisci Rosae-Sinensis 20 parts, Radix Phyllanthi cochinchinensis 12 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| TWI736023B (en) * | 2019-11-18 | 2021-08-11 | 大仁科技大學 | Urena lobate extract, preparation method and use thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI736023B (en) * | 2019-11-18 | 2021-08-11 | 大仁科技大學 | Urena lobate extract, preparation method and use thereof |
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