CN105213677A - A kind of Chinese medicinal film for topical anesthesia and preparation method thereof - Google Patents
A kind of Chinese medicinal film for topical anesthesia and preparation method thereof Download PDFInfo
- Publication number
- CN105213677A CN105213677A CN201510721389.3A CN201510721389A CN105213677A CN 105213677 A CN105213677 A CN 105213677A CN 201510721389 A CN201510721389 A CN 201510721389A CN 105213677 A CN105213677 A CN 105213677A
- Authority
- CN
- China
- Prior art keywords
- anesthesia
- solution
- chinese medicinal
- film
- chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of Chinese medicinal film for topical anesthesia, the material of main part of described Chinese medicinal film is face paper or facial mask cloth, it is characterized in that, material of main part infiltrates Chinese drug anesthesia composition; Described Chinese drug anesthesia composition is extracted by Venenum Bufonis, Rhizoma Pinelliae, Rhizoma Arisaematis, Pericarpium Zanthoxyli, Borneolum Syntheticum, Camphora and Herba Menthae and obtains.Chinese medicine extract of the present invention anesthesia facial film can realize local skin anesthesia at short notice, have rapid-action, effect is strong and lasting, the penetration power feature such as larger by force.
Description
Technical field
The present invention relates to a kind of surface surgical anesthesia film material, particularly a kind of film material containing Chinese drug anesthesia composition, belongs to field of medical technology.
Background technology
Present social rapid advances, life is more and more rich, and it is also more and more stronger that people pursue beautiful hope, and the beauty and shaping demand particularly for skin is particularly vigorous.Beautifying skin operation adopts the method for radiating such as luminous energy, heat energy to carry out face-lifting to skin to beautify more, and this wherein has the rising of temperature or the intense stimulus of local skin unavoidably.These temperature raise or intense stimulus can bring pain to face-lifting personage, affect the cosmetic surgery impression of client on the one hand; On the other hand, pain can cause the automatic activity of client, and the surgical work of interference face-lifting doctor, affects cosmetic outcome.
Mainly utilize Western medicine anesthetis to carry out anaesthetic treatment for skin irritant control method in prior art, anesthetics consumption can be reduced in order to cost-saving or do not anaesthetize when some cosmetic surgeries are less.When not anaesthetizing, face-lifting personage can be subject to the hardship of a large amount of pain, does not utilize post-operative recovery.
When employing anesthetics on a small quantity, because anesthetics mostly is oral or injecting anesthetic medicine, selectivity is poor, and anaesthetic effect is barely satisfactory.And the individual sensitivity for anesthetics is different, usually there will be the malpractice of anaesthetizing insufficient or overdose of anesthesia, adds a large amount of uncertainty and risk factors to operation process.
Summary of the invention
To the object of the invention is to overcome in prior art anaesthetic effect in operation on skin process not good, affect cosmetic surgery effect and there is the deficiency of great risk, a kind of Chinese medicinal film for topical anesthesia and preparation method thereof is provided.
In order to realize foregoing invention object, the invention provides following technical scheme:
For a Chinese medicinal film for topical anesthesia, the material of main part of described Chinese medicinal film is face paper or facial mask cloth, and material of main part infiltrates Chinese drug anesthesia composition.
Described Chinese drug anesthesia composition is extracted by Venenum Bufonis, Rhizoma Pinelliae, Rhizoma Arisaematis, Pericarpium Zanthoxyli, Borneolum Syntheticum, Camphora and Herba Menthae and obtains.
Composition containing multiple anesthetic action in the formula of Chinese medicinal film of the present invention, wherein Venenum Bufonis has the effects such as anesthesia, heart tonifying, boosting, antiinflammatory, removing toxic substances and promoting subsidence of swelling.The pain relieving of Rhizoma Pinelliae externally used detumescence.Rhizoma Arisaematis is expellingged wind and relieving convulsion, mass dissipating and swelling eliminating, and life uses external treatment carbuncle, snake bite and insect sting.Pericarpium Zanthoxyli external warming middle-JIAO to relieve pain, killing parasites for relieving itching.Borneolum Syntheticum has refreshment of having one's ideas straightened out, the loose poison of heat clearing away, effect of improving acuity of vision and removing nebula; Camphora is applied to skin gentle stimulation and antisepsis, and similar Herba Menthae, has refrigerant sense, and this is the effect owing to stimulating Cold receptor, has slight local anesthesia effect.Fructus Piperis, warming spleen and stomach for dispelling cold, wherein contained piperine has analgesic effect.Mentholum acts on sensory nerve ending, and can make sensory paralyses, external has anesthetic action.Apply above formula Chinese medicine extract and can realize local skin anesthesia at short notice as the Chinese medicinal film of main anesthetic composition, have rapid-action, effect is strong and lasting, the penetration power feature such as larger by force, is convenient to the carrying out of surface skin plastic aesthetic surgery.
Further, the raw material weight number ratio of described Chinese drug anesthesia constituents extraction is Venenum Bufonis: Rhizoma Pinelliae: Rhizoma Arisaematis: Pericarpium Zanthoxyli: Borneolum Syntheticum: Camphora: Herba Menthae=5-10:10-25:10-25:8-20:10-25:10-25:10-25.Preferred its raw material weight number ratio=5-8:12-18:12-18:8-12:12-18:12-18:12-18.Most preferred raw material weight number ratio=6:15:15:10:15:15:15.
Chinese medicinal film of the present invention has soft form, and can be attached to skin surface completely as common facial film/body film, Chinese medicine ingredients transdermal penetration wherein enters surface skin.Can realize noinvasive administration, and administration process has good selectivity, can for treating that the localized skin surface anaesthetic effect of face-lifting is good.Consider, Chinese medicinal film administering mode of the present invention carries out administration by the medicine membrane material of 1:1 area ratio to skin, anaesthesia dosage easily controls, anesthesia face-mask material that can be different according to surgery situation different designs, content of active component on the medicine film of wherein unit are is stablized, operation consent has cut out anesthetics film according to anaesthetic skin area difference, efficient, the accurate corresponding anesthesia of scope can need to carry out administration of anaesthesia, avoid the consumption of other for oral administration or drug administration by injection, scope control not problem accurately.
Further, the extracting method of Chinese drug anesthesia composition is: by Venenum Bufonis, Rhizoma Pinelliae, Rhizoma Arisaematis, Pericarpium Zanthoxyli, Borneolum Syntheticum, Camphora and Herba Menthae, soak, heating, keep micro-boiling, decoct, filter, medicinal residues add decocting 30-60 minute, filter, merge extracted twice liquid, water-bath is concentrated into 20ml (being equivalent to crude drug gross weight 1-5g/ml), 0-8 DEG C of preservation, preferably 4 DEG C of preservations.Repeat this scheme and prepare a certain amount of extracting solution containing Chinese drug anesthesia composition.The leaching process of Chinese drug anesthesia composition adopts gentle decoction method, and extraction conditions is gentle, does not introduce other irritating chemical composition.Through decocting the Chinese medicine dreg composition extracted, due to more not simple containing other chemical composition processing procedure, the problem of waste pollution environment can not be caused.Can decoct by direct heating in practical application, and do not soak separately, immersion effectively can soften raw material, reduces side reaction and occurs.
Further, also containing following helper component on described anesthetics film: one or more in hydroxypropyl emthylcellulose, glycerol, ethanol, Polyethylene Glycol, polyvinylpyrrolidone, methyl parahydroxybenzoate and tween 80.Importantly Chinese drug anesthesia composition in anesthetics film, add the morphological stability that a certain amount of auxiliary element can strengthen anesthetics film, avoid the difference of medicine film product excessive, simultaneously, auxiliary element effectively can extend the pot-life of medicine film, avoid face-mask material that rotten deterioration occurs in preservation process, impact uses.Wherein methyl parahydroxybenzoate adds application as antiseptic, prevents bacteria breed, extends facial film storage cycle.Tween 80 has emulsification, can form emulsion by emulsifying medicinal liquid, protection Chinese medicine ingredients dispersibility and stability.Auxiliary element prepares infiltration solution together with Chinese drug anesthesia composition, then infiltrates on the material of main part of Chinese medicinal film.
Hydroxypropyl emthylcellulose (HPMC), has another name called hypromellose, HPMC, is to select the gossypin of high purity as raw material, obtains in the basic conditions, have the effect of thickening, emulsifying through special etherificate.HPMC has hot gelling properties, form gel after the heating of product water solution to separate out, add HPMC more can be conducive to film morphology Control as auxiliary material, when using the Chinese medicinal film containing Chinese drug anesthesia composition of the present invention, its structure is more stable, the speed discharging Chinese drug anesthesia composition is more stable, the excellent effect of surperficial local anesthesia.
Glycerol, ethanol, Polyethylene Glycol all have good water-retaining property, there is moisturizing, moistening effect, moisture evaporation is prevented when long-term preservation, the moisture in Chinese medicinal film can be kept to stablize, the osmotic concentration controlling medicine membrane material remains in the scope of setting, avoid the dry of medicine film or solidification, improve the affinity of medicine film and skin, promote the result of use of Chinese medicinal narcotic film.Wherein ethanol can also increase the effect that permeability is absorbed by the skin fast by the Chinese drug anesthesia composition in medicine film.
Polyvinylpyrrolidone (PVP) is a kind of synthesizing water-solubility macromolecular compound, has film property, caking property, hygroscopicity, solubilising or cohesion, has very outstanding physiological compatibility especially.Have good protective effect for the anesthetic composition in medicine film, PVP and human body surface skin have extremely outstanding affinity simultaneously, can effectively promote that anesthetic composition enters skin corium through epidermis, realize anesthesia potency.Preferably the levels of viscosity of PVP-K30, PVP-K30 is moderate, be applied to comprehensive surface in Chinese medicine film best, and PVP-K30 easily obtains, and just can obtain colory raw material with extremely low price, has inexpensive feature.
Further, material of main part infiltrates in solution and obtains by Chinese medicinal film.Hygroscopic capacity after the infiltration of Chinese medicinal film is, every 100 square centimeters infiltrate solution containing 4-10ml, and preferably 5-8ml infiltrates solution.The surface of Chinese medicinal film infiltrates rear containing suitable infiltration solution, better can be attached to skin surface, conveniently be fitted on skin and carry out practical application.Infiltrate solution not easily to be controlled by the substrate of film material more than after 10ml, in film Surface runoff, the uniformity affecting anesthetics film controls, and is unfavorable for the equalization anesthetic action of skin surface.
Further, in described infiltration solution: every 1000ml infiltrates the extracting solution containing 5-150ml Chinese drug anesthesia composition in solution.Correspond in every ml Chinese drug anesthesia constituents extraction liquid that the ratio of the above-mentioned crude drug of 1-5g is concentrated to be formed, accurately control Chinese medicine ingredients content wherein, the gross weight of corresponding is crude drug composition.The concentration of extracting solution through designing of Chinese drug anesthesia composition, containing a large amount of anesthetic composition in every milliliter of extracting solution, the Chinese medicine ingredients consumption of design extracting solution, better can control the content ratio of auxiliary element, the dispersion being more conducive to anaesthetic agents composition plays a role.
Further, the usage ratio of helper component in above-mentioned infiltration solution: every 1000ml infiltrates in solution containing 30-50g hydroxypropyl emthylcellulose, 30-50g glycerol, 10-20g ethanol, 100-150g Polyethylene Glycol, 10-20g polyvinylpyrrolidone, 0.5-1g methyl parahydroxybenzoate, 5-8g tween 80.Infiltrate in solution preparation process and carry out standardize solution with water.In auxiliary element, various composition all has certain filming function or promotes effect of infiltration, but give play to best anesthesia drug effect, accurate adjustment is also needed to control the amount ratio of various composition, it is good to only have the eurythmy of each auxiliary element, better can improve Chinese medicinal narcotic film effect in practical application.
Present invention also offers a kind of method preparing the above-mentioned Chinese medicinal film for topical anesthesia, comprise the following steps:
(1) auxiliary element is got in proportion.
Solution A: by methyl parahydroxybenzoate and ethanol mixed dissolution even.
Solution B: join in hydroxypropyl methylcellulose by Polyethylene Glycol and polyvinylpyrrolidone, stirs to mucus shape.
(2) extracting solution of solution A, glycerol, Chinese drug anesthesia composition is joined in solution B, add water, stir, add tween 80, stir and form emulsus, obtain infiltration solution.
(3) face paper or facial mask cloth are infiltrated in above-mentioned infiltration solution, or be coated on face paper or facial mask cloth by above-mentioned infiltration solution, the content controlling face paper or facial mask cloth infiltrate solution is every 100 square centimeters and infiltrates solution containing 4-10ml.
Further, step (4) is also comprised: the Chinese medicinal film that above-mentioned infiltration is good is packaged into pouch/parcel.Then Co 60 sterilization is used.After being distributed into parcel, the size of Chinese medicinal film is distributed complete, transports before application, stores conveniently.Co 60 sterilization has efficiently, low-risk feature, and the loss amount of Chinese drug anesthesia composition is little, and anesthetic action is reliable and stable.
compared with prior art, beneficial effect of the present invention:
1. the Chinese medicinal film of topical anesthesia of the present invention, adopts common film paper/film cloth as substrate, is scattered in by Chinese drug anesthesia ingredient solution and infiltrates in solution, be evenly distributed in substrate, ensures Chinese medicine ingredients uniformly penetrating in application process, evenly anaesthetizes, convenient and swift.Anaesthetic effect is good, meet the requirement of local cosmetic surgery treatment, and the consumption of anesthetic composition wherein easily controls, and has positive help for face-lifting personage and face-lifting doctor.
2. Chinese medicine extract anesthetics film of the present invention can realize local skin anesthesia at short notice, have rapid-action, effect is strong and lasting, the penetration power feature such as larger by force.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following embodiment, all technology realized based on content of the present invention all belong to scope of the present invention.Percentage ratio not specified in the present invention is all weight percentage.
embodiment 1
Get Venenum Bufonis 6 grams, Rhizoma Pinelliae 15 grams, Rhizoma Arisaematis 15 grams, Pericarpium Zanthoxyli 10 grams, Borneolum Syntheticum 15 grams, Camphora 15 grams, Herba Menthae 15 grams, add 200ml soak by water 30 minutes, filter, filtering residue adds 200ml soak by water 30 minutes, and mixing filtrate, is concentrated into 20ml, obtains Chinese medicine extraction liquid.
embodiment 2
Chinese medicine extraction liquid 20ml embodiment 1 prepared and 30g hydroxypropyl emthylcellulose, 20g glycerol, 10g ethanol, 80g Polyethylene Glycol, 8g polyvinylpyrrolidone, 0.3g methyl parahydroxybenzoate, 4g tween 80 mix, add water to 500ml, stir, obtain the infiltration solution composition 500ml to be coated containing Chinese drug anesthesia composition.
embodiment 3
Infiltration solution embodiment 2 prepared is coated on the non-woven fabrics of the thick super softness of 0.3mm, and every 100 square centimeters of these infiltration solution of coating 6ml obtain the Chinese medicinal film (facial mask cloth substrate) containing Chinese drug anesthesia composition.
embodiment 4
Infiltration solution embodiment 2 prepared is coated on face paper, and every 100 square centimeters of coating 5ml infiltration solution obtain the Chinese medicinal film (paper substrates) containing Chinese drug anesthesia composition.
embodiment 5
Chinese medicine extraction liquid 20ml embodiment 1 prepared and 25g hydroxypropyl emthylcellulose, 30ml glycerol, 12ml ethanol, 110ml Polyethylene Glycol, 8g polyvinylpyrrolidone, 0.4g methyl parahydroxybenzoate, 5g tween 80 mix, add water to 800ml, stir, obtain the infiltration solution composition 800ml to be coated containing Chinese drug anesthesia composition.
embodiment 6
Infiltration solution embodiment 5 prepared is coated on face paper, and every 100 square centimeters of coating 8ml infiltration solution obtain the Chinese medicinal film (paper substrates) containing Chinese drug anesthesia composition.
embodiment 7
Get Venenum Bufonis 10 grams, Rhizoma Pinelliae 10 grams, Rhizoma Arisaematis 10 grams, Pericarpium Zanthoxyli 12 grams, Borneolum Syntheticum 10 grams, Camphora 18 grams, Herba Menthae 12 grams, adds 400ml water soaking 2 hours minutes, decocts 25 minutes, filter, filtering residue adds 200ml soak by water 20 minutes, and mixing filtrate, is concentrated into 16ml, obtain Chinese medicine extraction liquid, be stored in the refrigerator of 4 DEG C.
embodiment 8
Get 40g hydroxypropyl emthylcellulose, 50g glycerol, 10g ethanol, 150g Polyethylene Glycol, 10g polyvinylpyrrolidone, 1g methyl parahydroxybenzoate, 5g tween 80.Methyl parahydroxybenzoate and ethanol mixed dissolution is even, obtain solution A.Polyethylene Glycol and polyvinylpyrrolidone are joined in hydroxypropyl methylcellulose, stirs to mucus shape, obtain solution B.Extracting solution 16ml, solution A and the glycerol embodiment 7 prepared add in solution B, add water to 1000ml, stir, add tween 80, stir and form emulsus infiltration solution.Infiltrated by facial mask cloth in above-mentioned infiltration solution, the content controlling facial mask cloth infiltrates solution is every 100 square centimeters and infiltrates solution containing 10ml, prepares the Chinese medicinal film of Chinese drug anesthesia reagent.This Chinese medicinal film is packaged into pouch, uses Co 60 sterilization.
embodiment 9
Get Venenum Bufonis 20 grams, Rhizoma Pinelliae 20 grams, Rhizoma Arisaematis 15 grams, Pericarpium Zanthoxyli 18 grams, Borneolum Syntheticum 8 grams, Camphora 14 grams, Herba Menthae 16 grams, adds 400ml water soaking 2 hours minutes, decocts 25 minutes, filter, filtering residue adds 200ml soak by water 20 minutes, and mixing filtrate, is concentrated into 22ml, obtain Chinese medicine extraction liquid, be stored in the frost-free refrigerator of 0 DEG C.
0.8g methyl parahydroxybenzoate is dissolved in 12ml ethanol, obtains solution A.130g Polyethylene Glycol and 18g polyvinylpyrrolidone are joined in hydroxyl 40g third methylcellulose, stirs to mucus shape, obtain solution B.Add in solution B by the Chinese medicine extraction liquid 20ml of above-mentioned preparation, solution A and 40g glycerol, the capacity that adds water to while stirring, close to 196ml, stirs, and adds 4g tween 80, stirs and forms emulsus infiltration solution.Infiltrated by facial mask cloth in above-mentioned infiltration solution, the content controlling facial mask cloth infiltrates solution is every 100 square centimeters and infiltrates solution containing 6ml, prepares the Chinese medicinal film of Chinese drug anesthesia reagent.Be distributed into parcel, use Co 60 sterilization.
Claims (10)
1. for a Chinese medicinal film for topical anesthesia, the material of main part of described Chinese medicinal film is face paper or facial mask cloth, it is characterized in that, material of main part infiltrates Chinese drug anesthesia composition;
Described Chinese drug anesthesia composition is extracted by Venenum Bufonis, Rhizoma Pinelliae, Rhizoma Arisaematis, Pericarpium Zanthoxyli, Borneolum Syntheticum, Camphora and Herba Menthae and obtains.
2. the Chinese medicinal film for topical anesthesia according to claim 1, it is characterized in that, the raw material weight number ratio of described Chinese drug anesthesia constituents extraction is Venenum Bufonis: Rhizoma Pinelliae: Rhizoma Arisaematis: Pericarpium Zanthoxyli: Borneolum Syntheticum: Camphora: Herba Menthae=5-10:10-25:10-25:8-20:10-25:10-25:10-25.
3. the Chinese medicinal film for topical anesthesia according to claim 1, it is characterized in that, the raw material weight number ratio of described Chinese drug anesthesia constituents extraction is Venenum Bufonis: Rhizoma Pinelliae: Rhizoma Arisaematis: Pericarpium Zanthoxyli: Borneolum Syntheticum: Camphora: Herba Menthae=5-8:12-18:12-18:8-12:12-18:12-18:12-18.
4. the Chinese medicinal film for topical anesthesia according to claim 1, it is characterized in that, the raw material weight number ratio of described Chinese drug anesthesia constituents extraction is Venenum Bufonis: Rhizoma Pinelliae: Rhizoma Arisaematis: Pericarpium Zanthoxyli: Borneolum Syntheticum: Camphora: Herba Menthae=6:15:15:10:15:15:15.
5. the Chinese medicinal film for topical anesthesia according to claim 1, is characterized in that, the extracting method of Chinese drug anesthesia composition is: by Venenum Bufonis, Rhizoma Pinelliae, Rhizoma Arisaematis, Pericarpium Zanthoxyli, Borneolum Syntheticum, Camphora and Herba Menthae, soak, heating, keeps micro-and boils, and decocts, filter, medicinal residues add decocting 30-60 minute, filter, and merge extracted twice liquid, be concentrated in extracting solution and be equivalent to crude drug gross weight 1-5g/ml, namely obtain the extracting solution containing Chinese drug anesthesia composition.
6. the Chinese medicinal film for topical anesthesia according to claim 1, it is characterized in that, also containing following helper component on described anesthesia facial film: one or more in hydroxypropyl emthylcellulose, glycerol, ethanol, Polyethylene Glycol, polyvinylpyrrolidone, methyl parahydroxybenzoate and tween 80.
7. the Chinese medicinal film for topical anesthesia according to claim 1, is characterized in that, material of main part infiltrates in solution and obtains by Chinese medicinal film; Hygroscopic capacity after the infiltration of Chinese medicinal film is, every 100 square centimeters infiltrate solution containing 4-10ml.
8. the Chinese medicinal film for topical anesthesia according to claim 7, is characterized in that, in described infiltration solution: every 1000ml infiltrates the extracting solution containing 5-150ml Chinese drug anesthesia composition in solution.
9. the Chinese medicinal film for topical anesthesia according to claim 7, it is characterized in that, the usage ratio of helper component in above-mentioned infiltration solution: every 1000ml infiltrates in solution containing 30-50g hydroxypropyl emthylcellulose, 30-50g glycerol, 10-20g ethanol, 100-150g Polyethylene Glycol, 10-20g polyvinylpyrrolidone, 0.5-1g methyl parahydroxybenzoate, 5-8g tween 80.
10. prepare a method for the above-mentioned Chinese medicinal film for topical anesthesia, comprise the following steps:
(1) auxiliary element is got in proportion;
Solution A: by methyl parahydroxybenzoate and ethanol mixed dissolution even;
Solution B: join in hydroxypropyl methylcellulose by Polyethylene Glycol and polyvinylpyrrolidone, stirs to mucus shape;
(2) extracting solution of solution A, glycerol, Chinese drug anesthesia composition is joined in solution B, add water, stir, add tween 80, stir and form emulsus, obtain infiltration solution;
(3) face paper or facial mask cloth are infiltrated in above-mentioned infiltration solution, or be coated on face paper or facial mask cloth by above-mentioned infiltration solution, the content controlling face paper or facial mask cloth infiltrate solution is every 100 square centimeters and infiltrates solution containing 4-10ml.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510721389.3A CN105213677A (en) | 2015-10-30 | 2015-10-30 | A kind of Chinese medicinal film for topical anesthesia and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510721389.3A CN105213677A (en) | 2015-10-30 | 2015-10-30 | A kind of Chinese medicinal film for topical anesthesia and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105213677A true CN105213677A (en) | 2016-01-06 |
Family
ID=54983189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510721389.3A Pending CN105213677A (en) | 2015-10-30 | 2015-10-30 | A kind of Chinese medicinal film for topical anesthesia and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105213677A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105596615A (en) * | 2016-01-25 | 2016-05-25 | 青岛大学附属医院 | Anesthesia, analgesia and inflammation diminishing traditional Chinese medicine |
| CN111420021A (en) * | 2020-05-26 | 2020-07-17 | 袁浩峥 | Traditional Chinese medicine preparation for anesthesia and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101757333A (en) * | 2008-12-24 | 2010-06-30 | 天津市中宝制药有限公司 | External traditional Chinese medicament preparation for treating arthralgia |
| CN103690515A (en) * | 2013-12-09 | 2014-04-02 | 中国人民解放军第四军医大学 | Surface anesthesia membrane for laser therapy and preparation method thereof |
-
2015
- 2015-10-30 CN CN201510721389.3A patent/CN105213677A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101757333A (en) * | 2008-12-24 | 2010-06-30 | 天津市中宝制药有限公司 | External traditional Chinese medicament preparation for treating arthralgia |
| CN103690515A (en) * | 2013-12-09 | 2014-04-02 | 中国人民解放军第四军医大学 | Surface anesthesia membrane for laser therapy and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 吴金华等: "中药麻醉的现代研究进展", 《中兽医学杂志》 * |
| 杨升华等: "中药表面麻醉剂的应用", 《中医外治杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105596615A (en) * | 2016-01-25 | 2016-05-25 | 青岛大学附属医院 | Anesthesia, analgesia and inflammation diminishing traditional Chinese medicine |
| CN111420021A (en) * | 2020-05-26 | 2020-07-17 | 袁浩峥 | Traditional Chinese medicine preparation for anesthesia and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109394737A (en) | Medical cold application and preparation method thereof | |
| US20150147415A1 (en) | Agent for promoting hair growth and method for preparing same | |
| CN104258456A (en) | Wound repair gel containing hexagonal mesoporous silicon and preparation method thereof | |
| CN104274546B (en) | A kind of external medicine composition, traditional Chinese medicine for outer use and its preparation method and application | |
| CN1806823B (en) | Externally applied wind-expelling Chinese medicinal composition plaster | |
| CN101934015B (en) | Traditional Chinese medicinal composition for treating thyroid and method for preparing dispelling-goitre cataplasm thereof | |
| CN106138491B (en) | A kind of weight-reducing Chinese medicine compound prescription drug paste | |
| CN105213677A (en) | A kind of Chinese medicinal film for topical anesthesia and preparation method thereof | |
| CN109125207A (en) | A kind of plant compound of antibacterial anti-acne and its preparation method and application | |
| CN100462098C (en) | Chinese medicine ointment for treating bone disease and its preparing method | |
| KR102178353B1 (en) | patch composition for diabetes mellitus and patch manufacturing method using the same | |
| CN108355038A (en) | The Chinese medicine bathing instant granular of improvement qi deficiency to blood stasis rheumatism and preparation and application method | |
| CN104474577A (en) | Laser beatifying postoperation dressing and preparation method thereof | |
| CN100525751C (en) | Meridian point therapeutic plaster of high polymer multi hole energy gathering ion and its preparation method and application | |
| CN103550675A (en) | Pain relieving plaster | |
| CN100500139C (en) | External use medicine for treating rheumatic arthritis, and its preparation method | |
| CN104138499B (en) | A kind of Chinese medicine composition, its preparation method and its application for treating tinea of feet and hands and onychomycosis | |
| CN102670735A (en) | Anti-dandruff Chinese medicinal composition and application thereof to anti-dandruff external application agent | |
| CN106620514A (en) | Traditional Chinese medicine hydrophilic gel patch for treating dysmenorrheal and preparation method of traditional Chinese medicine hydrophilic gel patch | |
| CN102000176B (en) | Medicine composition for treating burns and scalds and preparation method thereof | |
| CN103751073B (en) | Compound traditional Chinese medicine extract with function of removing dandruff, and application | |
| CN109260345A (en) | A kind of callus promoting blood circulation composition and its preparation and preparation method | |
| CN109395050A (en) | Paediatrics external application massage the ointment formula, preparation method and application for treating diarrhea | |
| CN108434299B (en) | Pharmaceutical composition for treating scapulohumeral periarthritis and preparation method and spray thereof | |
| CN108272772A (en) | A kind of surface surgical anesthesia facial mask |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160106 |
|
| RJ01 | Rejection of invention patent application after publication |