CN105194633A - Chinese-western medicine compound preparation for treating influenza - Google Patents

Chinese-western medicine compound preparation for treating influenza Download PDF

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Publication number
CN105194633A
CN105194633A CN201510726567.1A CN201510726567A CN105194633A CN 105194633 A CN105194633 A CN 105194633A CN 201510726567 A CN201510726567 A CN 201510726567A CN 105194633 A CN105194633 A CN 105194633A
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parts
radix
western medicine
compound preparation
chinese medicine
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张庆霞
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Abstract

The invention discloses a Chinese-western medicine compound preparation for treating influenza. The Chinese-western medicine compound preparation is prepared from raw materials in parts by weight as follows: 5-9 parts of honeysuckle, 6-8 parts of dried ginseng, 4-6 parts of white paeony roots, 4-6 parts of dahurian angelica roots, 5-8 parts of great burdock achene, 5-8 parts of common achyranthes herb, 6-8 parts of thinleaf adina fruit, 6-8 parts of bergamot, 4-6 parts of perilla leaves, 3-5 parts of Chinese lobelia herb, 3-5 parts of hawthorn fruits, 3-5 parts of Chinese thorowax roots, 0.5-1 part of acetaminophen, 0.01-0.02 parts of chlorphenamine maleate and 0.01-0.02 parts of caffeine. The Chinese-western medicine compound preparation can be in the form of granules, capsules, soft capsules, tablets, dispersible tablets, effervescent tablets, chewable tablets or pills, has efficacy of heat clearing and detoxicity, can be used for treating a headache, a fever, nasal obstruction, coughs and sore throat caused by influenza, takes effect quickly and is safe and reliable to take, and the cure rate is high.

Description

A kind of Chinese medicine and western medicine compound preparation for the treatment of flu
Technical field
The present invention relates to a kind of coldrex, specifically a kind of Chinese medicine and western medicine compound preparation for the treatment of flu.
Background technology
Flu, being commonly called as " cold ", also referred to as upper respiratory tract infection, is a kind of respiratory tract commonly encountered diseases caused by multiple virus, and comparatively suddenly, early symptom has pharyngeal dryly to itch or burning sensation, sneeze, nasal obstruction, watery nasal discharge to onset, can with pharyngalgia.Chinese medicine thinks that flu is when taking advantage of human body to drive evil scarce capacity by the heresy of ten six climate exopathogens, invades from human body fur or mouth and nose, and invasion and attack lung is defended caused by fur.To experience ailment said due to cold or exposure, the fiery cold-evil that holds concurrently invades person caused by human body, is called exterior syndrome due to wind-cold; Hold concurrently person caused by burning hot evil infringement human body, is called wind heat exterior syndrome.Clinically based on exterior syndrome, common lung meridian symptom.Exterior syndrome due to wind-cold main manifestations is that aversion to cold is heavy, rare white expectorant, the not thirsty or thirsty desire for hot drinks of mouth, white and thin fur are told in generate heat light, lossless, headache general pain, stuffy nose with watery discharge, cough; Wind heat exterior syndrome main manifestations is heating weight, micro evil wind, distending pain in the head, have antiperspirant, red swelling and pain of throat, cough, expectorant are vigorous or yellow, yellow thick nasal discharge of having a stuffy nose, thirst and liking drink, the tip of the tongue limit are red, the micro-Huang of white and thin fur.
Be main mainly with chemicals at present conventional prescription collocation, as: antipyretic analgesic, nasal mucosa vasoconstriction, histamine antagonist, central stimulants, antiviral agents etc., but table controlled often by these medicines, can not solve its root problem.Therefore, seek to control and show double effecting a permanent cure, the Chinese medicine showing originally to take into account has become the research topic paid close attention to, and the pure Chinese medicinal preparation of some treatment flu or coldrexs of Integrated TCM are also arisen at the historic moment, but the effect of these medicines is also undesirable.Therefore, seeking more rationally effective Chinese medicine preparation is the direction with Practical significance research.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine and western medicine compound preparation for the treatment of flu, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
Treat a Chinese medicine and western medicine compound preparation for flu, comprise according to the raw material of weight portion: Flos Lonicerae 5-9 part, Rhizoma Zingiberis 6-8 part, Radix Paeoniae Alba 4-6 part, Radix Angelicae Dahuricae 4-6 part, Fructus Arctii 5-8 part, Radix achyranthis asperae (Herba Achyranthis Asperae) 5-8 part, Fructus Adinae 6-8 part, Folium vilicis Negundo 6-8 part, Folium Perillae 4-6 part, Herba Lobeliae Chinensis 3-5 part, Fructus Crataegi 3-5 part, Radix Bupleuri 3-5 part, acetaminophen 0.5-1 part, chlorphenamine maleate 0.01-0.02 part, caffeine 0.01-0.02 part.
As the further scheme of the present invention: the Chinese medicine and western medicine compound preparation of described treatment flu, comprises according to the raw material of weight portion: Flos Lonicerae 7 parts, Rhizoma Zingiberis 7 parts, the Radix Paeoniae Alba 5 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Arctii 6.5 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 6.5 parts, Fructus Adinae 7 parts, Folium vilicis Negundo 7 parts, Folium Perillae 5 parts, Herba Lobeliae Chinensis 4 parts, Fructus Crataegi 4 parts, Radix Bupleuri 4 parts, acetaminophen 0.75 part, chlorphenamine maleate 0.015 part, caffeine 0.015 part.
As the present invention's further scheme: described Chinese medicine and western medicine compound preparation is granule, capsule, soft capsule, tablet, dispersible tablet, effervescent tablet, chewable tablet or pill.
As the present invention's further scheme: the preparation method of the Chinese medicine and western medicine compound preparation of described treatment flu, its step is as follows: Flos Lonicerae, Rhizoma Zingiberis, the Radix Paeoniae Alba, the Radix Angelicae Dahuricae, Fructus Arctii, Radix achyranthis asperae (Herba Achyranthis Asperae), Fructus Adinae, Folium vilicis Negundo, Folium Perillae, Herba Lobeliae Chinensis, Fructus Crataegi and Radix Bupleuri 12 taste Chinese medicine are decocted with water secondary, each decoction 2 hours, collecting decoction, filter, filtrate is condensed into paste, dry, pulverize into fine powder; By acetaminophen, chlorphenamine maleate and caffeine three taste Western medicine porphyrize respectively, mix with above-mentioned 12 taste Chinese medicine extraction fine powders, sieve, both must comprise the preparation extract used of granule, capsule, soft capsule, tablet, dispersible tablet, effervescent tablet, chewable tablet, pill for preparation.
Compared with prior art, the invention has the beneficial effects as follows: heat-clearing and toxic substances removing, what cause for catching a cold has a headache and fever, nasal obstruction, cough, throat pain, and curative effect is fast, and cure rate is high, takes safe and reliable.
Detailed description of the invention
Be described in more detail below in conjunction with the technical scheme of detailed description of the invention to this patent.
Embodiment 1
Treat a Chinese medicine and western medicine compound preparation for flu, comprise according to the raw material of weight portion: Flos Lonicerae 5 parts, Rhizoma Zingiberis 6 parts, the Radix Paeoniae Alba 4 parts, the Radix Angelicae Dahuricae 4 parts, Fructus Arctii 5 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 5 parts, Fructus Adinae 6 parts, Folium vilicis Negundo 6 parts, Folium Perillae 4 parts, Herba Lobeliae Chinensis 3 parts, Fructus Crataegi 3 parts, Radix Bupleuri 3 parts, acetaminophen 0.5 part, chlorphenamine maleate 0.01 part, caffeine 0.01 part.
Embodiment 2
Treat a Chinese medicine and western medicine compound preparation for flu, comprise according to the raw material of weight portion: Flos Lonicerae 7 parts, Rhizoma Zingiberis 7 parts, the Radix Paeoniae Alba 5 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Arctii 6.5 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 6.5 parts, Fructus Adinae 7 parts, Folium vilicis Negundo 7 parts, Folium Perillae 5 parts, Herba Lobeliae Chinensis 4 parts, Fructus Crataegi 4 parts, Radix Bupleuri 4 parts, acetaminophen 0.75 part, chlorphenamine maleate 0.015 part, caffeine 0.015 part.
Embodiment 3
Treat a Chinese medicine and western medicine compound preparation for flu, comprise according to the raw material of weight portion: Flos Lonicerae 9 parts, Rhizoma Zingiberis 8 parts, the Radix Paeoniae Alba 6 parts, the Radix Angelicae Dahuricae 6 parts, Fructus Arctii 8 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 8 parts, Fructus Adinae 8 parts, Folium vilicis Negundo 8 parts, Folium Perillae 6 parts, Herba Lobeliae Chinensis 5 parts, Fructus Crataegi 5 parts, Radix Bupleuri 5 parts, acetaminophen 1 part, chlorphenamine maleate 0.02 part, caffeine 0.02 part.
Embodiment 4
The present embodiment provides a kind of extracting method for the treatment of the Chinese medicine and western medicine compound preparation of flu, and its concrete steps are as follows:
Getting of the prescription weight portion of the Chinese medicine and western medicine compound preparation of flu is treated: Flos Lonicerae 7 parts, Rhizoma Zingiberis 7 parts, the Radix Paeoniae Alba 5 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Arctii 6.5 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 6.5 parts, Fructus Adinae 7 parts, Folium vilicis Negundo 7 parts, Folium Perillae 5 parts, Herba Lobeliae Chinensis 4 parts, Fructus Crataegi 4 parts, Radix Bupleuri 4 parts, acetaminophen 0.75 part, chlorphenamine maleate 0.015 part, caffeine 0.015 part according to a kind of described in embodiment 2.
Flos Lonicerae, Rhizoma Zingiberis, the Radix Paeoniae Alba, the Radix Angelicae Dahuricae, Fructus Arctii, Radix achyranthis asperae (Herba Achyranthis Asperae), Fructus Adinae, Folium vilicis Negundo, Folium Perillae, Herba Lobeliae Chinensis, Fructus Crataegi and Radix Bupleuri 12 taste Chinese medicine are decocted with water secondary, each decoction 2 hours, collecting decoction, filter, filtrate is condensed into the paste (55 ~ 60 DEG C) that relative density is 1.25, dry, pulverize into fine powder; By acetaminophen, chlorphenamine maleate and caffeine three taste Western medicine porphyrize respectively, mix with above-mentioned 12 taste Chinese medicine extraction fine powders, sieve, both must comprise the preparation extract used of granule, capsule, soft capsule, tablet, dispersible tablet, effervescent tablet, chewable tablet, pill for preparation.
Embodiment 5
The present embodiment provides a kind of preparation method for the treatment of the Chinese medicine and western medicine compound preparation-tablet of flu, and its concrete steps are as follows:
Getting of the prescription weight portion of the Chinese medicine and western medicine compound preparation of flu is treated: Flos Lonicerae 7 parts, Rhizoma Zingiberis 7 parts, the Radix Paeoniae Alba 5 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Arctii 6.5 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 6.5 parts, Fructus Adinae 7 parts, Folium vilicis Negundo 7 parts, Folium Perillae 5 parts, Herba Lobeliae Chinensis 4 parts, Fructus Crataegi 4 parts, Radix Bupleuri 4 parts, acetaminophen 0.75 part, chlorphenamine maleate 0.015 part, caffeine 0.015 part according to a kind of described in embodiment 2.
Flos Lonicerae, Rhizoma Zingiberis, the Radix Paeoniae Alba, the Radix Angelicae Dahuricae, Fructus Arctii, Radix achyranthis asperae (Herba Achyranthis Asperae), Fructus Adinae, Folium vilicis Negundo, Folium Perillae, Herba Lobeliae Chinensis, Fructus Crataegi and Radix Bupleuri 12 taste Chinese medicine are decocted with water secondary, each decoction 2 hours, collecting decoction, filter, filtrate is condensed into the paste (55 ~ 60 DEG C) that relative density is 1.25, dry, pulverize into fine powder; By acetaminophen, chlorphenamine maleate and caffeine three taste Western medicine porphyrize respectively, mix with above-mentioned 12 taste Chinese medicine extraction fine powders, right amount of auxiliary materials, granulate, be pressed into 1000, sugar coating or film-coat, to obtain final product.
Described adjuvant comprises starch, sucrose, lactose, dextrin, pregelatinized Starch, microcrystalline Cellulose, mannitol, sorbitol, xylitol, methylcellulose, hydroxypropyl cellulose, hypromellose, sodium carboxymethyl cellulose, ethyl cellulose, polyvidone, Polyethylene Glycol, dried starch, carboxymethylstach sodium, low-substituted hydroxypropyl cellulose, cross-linked carboxymethyl cellulose sodium, polyvinylpolypyrrolidone, magnesium stearate, micropowder silica gel, Pulvis Talci, polyethylene glycols, one or more of sodium laurylsulfate are used in combination.
Embodiment 6
The present embodiment provides a kind of preparation method for the treatment of the Chinese medicine and western medicine compound preparation-granule of flu, and its concrete steps are as follows:
Getting of the prescription weight portion of the Chinese medicine and western medicine compound preparation of flu is treated: Flos Lonicerae 7 parts, Rhizoma Zingiberis 7 parts, the Radix Paeoniae Alba 5 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Arctii 6.5 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 6.5 parts, Fructus Adinae 7 parts, Folium vilicis Negundo 7 parts, Folium Perillae 5 parts, Herba Lobeliae Chinensis 4 parts, Fructus Crataegi 4 parts, Radix Bupleuri 4 parts, acetaminophen 0.75 part, chlorphenamine maleate 0.015 part, caffeine 0.015 part according to a kind of described in embodiment 2.
Flos Lonicerae, Rhizoma Zingiberis, the Radix Paeoniae Alba, the Radix Angelicae Dahuricae, Fructus Arctii, Radix achyranthis asperae (Herba Achyranthis Asperae), Fructus Adinae, Folium vilicis Negundo, Folium Perillae, Herba Lobeliae Chinensis, Fructus Crataegi and Radix Bupleuri 12 taste Chinese medicine are decocted with water secondary, each decoction 2 hours, collecting decoction, filter, filtrate is condensed into the paste (55 ~ 60 DEG C) that relative density is 1.25, dry, pulverize into fine powder; By acetaminophen, chlorphenamine maleate and caffeine three taste Western medicine porphyrize respectively, mix with above-mentioned 12 taste Chinese medicine extraction fine powders, right amount of auxiliary materials, add starch slurry granulation, drying, obtain granule.
Described accessory package contains: starch, sucrose, dextrin, lactose, methylcellulose, hydroxypropyl cellulose, hypromellose, sodium carboxymethyl cellulose, ethyl cellulose, magnesium stearate, micropowder silica gel, talcous one or more are used in combination.
Embodiment 7
The present embodiment provides a kind of preparation method for the treatment of the Chinese medicine and western medicine compound preparation-capsule of flu, and its concrete steps are as follows:
Getting of the prescription weight portion of the Chinese medicine and western medicine compound preparation of flu is treated: Flos Lonicerae 7 parts, Rhizoma Zingiberis 7 parts, the Radix Paeoniae Alba 5 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Arctii 6.5 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 6.5 parts, Fructus Adinae 7 parts, Folium vilicis Negundo 7 parts, Folium Perillae 5 parts, Herba Lobeliae Chinensis 4 parts, Fructus Crataegi 4 parts, Radix Bupleuri 4 parts, acetaminophen 0.75 part, chlorphenamine maleate 0.015 part, caffeine 0.015 part according to a kind of described in embodiment 2.
Flos Lonicerae, Rhizoma Zingiberis, the Radix Paeoniae Alba, the Radix Angelicae Dahuricae, Fructus Arctii, Radix achyranthis asperae (Herba Achyranthis Asperae), Fructus Adinae, Folium vilicis Negundo, Folium Perillae, Herba Lobeliae Chinensis, Fructus Crataegi and Radix Bupleuri 12 taste Chinese medicine are decocted with water secondary, each decoction 2 hours, collecting decoction, filter, filtrate is condensed into the paste (55 ~ 60 DEG C) that relative density is 1.25, dry, pulverize into fine powder; By acetaminophen, chlorphenamine maleate and caffeine three taste Western medicine porphyrize respectively, mix with above-mentioned 12 taste Chinese medicine extraction fine powders, right amount of auxiliary materials, fill and make capsule.
Described accessory package is starch-containing, sucrose, dextrin, lactose, microcrystalline Cellulose, pregelatinized Starch, mannitol, sorbitol, methylcellulose, hydroxypropyl cellulose, hypromellose, sodium carboxymethyl cellulose, ethyl cellulose, modified starch, magnesium stearate, silicon dioxide, micropowder silica gel, talcous one or more are used in combination.
Embodiment 8
The present embodiment provides a kind of preparation method for the treatment of the Chinese medicine and western medicine compound preparation-soft capsule of flu, and its concrete steps are as follows:
Getting of the prescription weight portion of the Chinese medicine and western medicine compound preparation of flu is treated: Flos Lonicerae 7 parts, Rhizoma Zingiberis 7 parts, the Radix Paeoniae Alba 5 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Arctii 6.5 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 6.5 parts, Fructus Adinae 7 parts, Folium vilicis Negundo 7 parts, Folium Perillae 5 parts, Herba Lobeliae Chinensis 4 parts, Fructus Crataegi 4 parts, Radix Bupleuri 4 parts, acetaminophen 0.75 part, chlorphenamine maleate 0.015 part, caffeine 0.015 part according to a kind of described in embodiment 2.
Flos Lonicerae, Rhizoma Zingiberis, the Radix Paeoniae Alba, the Radix Angelicae Dahuricae, Fructus Arctii, Radix achyranthis asperae (Herba Achyranthis Asperae), Fructus Adinae, Folium vilicis Negundo, Folium Perillae, Herba Lobeliae Chinensis, Fructus Crataegi and Radix Bupleuri 12 taste Chinese medicine are decocted with water secondary, each decoction 2 hours, collecting decoction, filter, filtrate is condensed into the paste (55 ~ 60 DEG C) that relative density is 1.25, dry, pulverize into fine powder; By acetaminophen, chlorphenamine maleate and caffeine three taste Western medicine porphyrize respectively, mix with above-mentioned 12 taste Chinese medicine extraction fine powders, right amount of auxiliary materials, mix homogeneously with disperse medium, make soft capsule liquid for subsequent use; Get gelatin, water mixing, dissolve, add glycerol, antiseptic, additives, stir under heating in water bath, after vacuumize degassing, insulation leaves standstill, and makes capsule material for subsequent use; By capsule liquid, capsule material liquid dripping from the pill dripping machine of double-deck water dropper respectively, make soft capsule, to obtain final product.
Described accessory package is starch-containing, sucrose, dextrin, lactose, microcrystalline Cellulose, pregelatinized Starch, mannitol, sorbitol, starch slurry, methylcellulose, hydroxypropyl cellulose, hypromellose, sodium carboxymethyl cellulose, ethyl cellulose, polyvidone, gelatin, Macrogol 4000 or 6000, modified starch, magnesium stearate, silicon dioxide, micropowder silica gel, talcous one or more are used in combination.
Described disperse medium, additives are soybean oil, Oleum Sesami, olive oil, Oleum Arachidis hypogaeae semen, triglyceride, oleic acid sorbitol ester, olein, Oleum Cocois C8/C10 monoglyceride, Oleum Cocois C8/C10 diglyceride, Oleum Cocois C8/C10 propylene glycol ester, Oleum Cocois triglyceride, Oleum Cocois triglyceride, olein, glyceryl linoleate, Polyethylene Glycol glyceryl laurate ester, Oleum helianthi monoglyceride, propylene glycol, Cera Flava, glyceryl monostearate, soybean lecithin, ethyl cellulose, one or more of Liquid Macrogol ~ 800 are used in combination.
Described antiseptic, additives be glycerol, propylene glycol, methyl parahydroxybenzoate, ethylparaben, propyl p-hydroxybenzoate, butyl p-hydroxybenzoate one or more are used in combination.
Above the better embodiment of this patent is explained in detail, but this patent is not limited to above-mentioned embodiment, in the ken that one skilled in the relevant art possesses, can also makes a variety of changes under the prerequisite not departing from this patent aim.

Claims (4)

1. treat the Chinese medicine and western medicine compound preparation of flu for one kind, it is characterized in that, comprise according to the raw material of weight portion: Flos Lonicerae 5-9 part, Rhizoma Zingiberis 6-8 part, Radix Paeoniae Alba 4-6 part, Radix Angelicae Dahuricae 4-6 part, Fructus Arctii 5-8 part, Radix achyranthis asperae (Herba Achyranthis Asperae) 5-8 part, Fructus Adinae 6-8 part, Folium vilicis Negundo 6-8 part, Folium Perillae 4-6 part, Herba Lobeliae Chinensis 3-5 part, Fructus Crataegi 3-5 part, Radix Bupleuri 3-5 part, acetaminophen 0.5-1 part, chlorphenamine maleate 0.01-0.02 part, caffeine 0.01-0.02 part.
2. the Chinese medicine and western medicine compound preparation for the treatment of flu according to claim 1, it is characterized in that, comprise according to the raw material of weight portion: Flos Lonicerae 7 parts, Rhizoma Zingiberis 7 parts, the Radix Paeoniae Alba 5 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Arctii 6.5 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 6.5 parts, Fructus Adinae 7 parts, Folium vilicis Negundo 7 parts, Folium Perillae 5 parts, Herba Lobeliae Chinensis 4 parts, Fructus Crataegi 4 parts, Radix Bupleuri 4 parts, acetaminophen 0.75 part, chlorphenamine maleate 0.015 part, caffeine 0.015 part.
3. the Chinese medicine and western medicine compound preparation for the treatment of flu according to claim 1, it is characterized in that, described Chinese medicine and western medicine compound preparation is granule, capsule, soft capsule, tablet, dispersible tablet, effervescent tablet, chewable tablet or pill.
4. one kind as arbitrary in claim 1-3 as described in the preparation method of Chinese medicine and western medicine compound preparation for the treatment of flu, it is characterized in that, its step is as follows: Flos Lonicerae, Rhizoma Zingiberis, the Radix Paeoniae Alba, the Radix Angelicae Dahuricae, Fructus Arctii, Radix achyranthis asperae (Herba Achyranthis Asperae), Fructus Adinae, Folium vilicis Negundo, Folium Perillae, Herba Lobeliae Chinensis, Fructus Crataegi and Radix Bupleuri 12 taste Chinese medicine are decocted with water secondary, each decoction 2 hours, collecting decoction, filter, filtrate is condensed into paste, dry, pulverize into fine powder; By acetaminophen, chlorphenamine maleate and caffeine three taste Western medicine porphyrize respectively, mix with above-mentioned 12 taste Chinese medicine extraction fine powders, sieve, both must comprise the preparation extract used of granule, capsule, soft capsule, tablet, dispersible tablet, effervescent tablet, chewable tablet, pill for preparation.
CN201510726567.1A 2015-10-26 2015-10-26 Chinese-western medicine compound preparation for treating influenza Pending CN105194633A (en)

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US10086026B2 (en) * 2016-06-27 2018-10-02 Uwais M. Syed Combined herbal and pharmaceutical composition and method
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Application publication date: 20151230