CN102526665B - Chinese medicinal particles for clearing heat, allaying fever and treating cold - Google Patents
Chinese medicinal particles for clearing heat, allaying fever and treating cold Download PDFInfo
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- CN102526665B CN102526665B CN 201210013661 CN201210013661A CN102526665B CN 102526665 B CN102526665 B CN 102526665B CN 201210013661 CN201210013661 CN 201210013661 CN 201210013661 A CN201210013661 A CN 201210013661A CN 102526665 B CN102526665 B CN 102526665B
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Abstract
The invention discloses Chinese medicinal particles for clearing heat, allaying fever and treating cold. The Chinese medicinal particles are prepared from chimonanthus nitens leaf, isatis root, wild chrysanthemum 3, verbena, stiff silkworm, cicada shell, common anemarrhena, heartleaf houttuynia herb, liquoric root, mint, Chinese atractylodes, fortune eupatorium herb, divaricate saposhnikovia root, scorched malt, scorched medicated leaven, scorched fructus crataegi, chicken gizzard membrane, rehmannia root, red paeony root, ginger, blighted wheat, Chinese globeflower flower, platycodon root and common selfheal fruit-spike serving as raw materials, and has the advantages of low cost, easiness for processing, remarkable curative effect, use safety, high curative rate, and the like.
Description
Technical field
The present invention relates to the field of Chinese medicines, being specifically related to a kind of is the medicinal granule of raw material treatment flu with Chinese medicine.
Background technology
Flu is that attacking human body caused because of exopathogen is the disease of main clinical manifestation with headache, nasal obstruction, nasal mucus, sneeze, aversion to wind and cold, heating, floating pulse etc.Flu all can be fallen ill the whole year, but with winter, spring be many.State of an illness the lighter claims " cold "; State of an illness weight person, and in a period, cause pandemicly, be called " influenza ".Western medicine class medicine of the prior art mostly is the medicine that slows down disease, slows down effect though can play the malaise symptoms such as caused heating, pain, cough of falling ill as the antipyretic-antalgic class medicine that generally uses, and can not play therapeutical effect at the cause of disease.In recent years, China approved several new drugs that are used for the treatment of influenza, flu, as SHUANGHUANGLIAN KELI, GANMAO QINGRE KELI etc., because this type of medicine has stronger inhibitory action to influenza virus, except can slowing down the symptom, and can shorten healing time, play the effect for the treatment of both the principal and secondary aspects of a disease, and have no side effect, be subjected to patient and medical personnel's welcome deeply.But compare the weak point that also existence is brought down a fever, pain relieving is slower with Western medicine class medicine.The preparation of clinical use mostly is and slightly obtains through refining agent in addition, and it is remarkable to lack drug effect, and effective ingredient and the mechanism of action are clear, and is quality controllable, dosage form advanced person's modern Chinese medicine.
Summary of the invention
Purpose of the present invention provides at above-mentioned weak point of the prior art just that a kind of active constituent content height and recipe quantity are little, fast, the analgesic effect of bringing down a fever significantly is used for the treatment of granule medicament of flu and preparation method thereof, and is evident in efficacy, with low cost, toxic and side effects is minimum.
Be achieved through the following technical solutions during the technical problem to be solved in the present invention.
Medicament of the present invention is made up of following weight portion:
Major ingredient: leaf of Chimonanthus Nitens 100-150 part, Radix Isatidis 50-60 part, Flos Chrysanthemi Indici 30-50 part, Herba Verbenae 10-15 part, Bombyx Batryticatus 10-20 part, Periostracum Cicadae 6-10 part, Rhizoma Anemarrhenae 11-16 part, Herba Houttuyniae 8-15 part, Radix Glycyrrhizae 5-10 part, Herba Menthae 8-12 part, Rhizoma Atractylodis 9-15 part, Herba Eupatorii 3-7 part, Radix Saposhnikoviae 10-15 part, Fructus Hordei Germinatus (parched to brown) 4-8 part, Massa Medicata Fermentata (parched to brown) 3-6 part, Fructus Crataegi (parched to brown) 2-5 part, Endothelium Corneum Gigeriae Galli 10-20 part, Rhizoma Phragmitis 13-18 part, Radix Paeoniae Rubra 4-8 part, Rhizoma Zingiberis Recens 5-10 part; Fructus Tritici Levis 10-15 part, Flos Trollii 5-10 part, Radix Platycodonis 12-16 part, Spica Prunellae 6-10 part;
Thickening agent 5-8 part, described thickening agent are any one in starch, maltodextrin, hydroxypropyl cellulose, hydroxypropyl emthylcellulose, sodium carboxymethyl cellulose, the carboxymethyl starch sodium;
Sweeting agent 3-5 part: described sweeting agent is any one in sucrose, maltose, mannose or the xylitol.
Medicament processing method of the present invention is preferably as follows step:
(1) takes by weighing various medicinal raw materials by said ratio, and choose the removal of impurity with manual method;
(2) raw material of select is dried under 60 ℃ of environment, and use ultraviolet radiation disinfection;
(3) with disintegrating apparatus raw material is broken into powder about 80 orders and even blend;
(4) powder after the mixing of step (3) gained is poured in the extraction still, the decocting of quoting that adds 10 times of raw material weights boiled 2 hours, and temperature is no more than 100 ℃, separation and Extraction liquid, pressure filtration, filtrate for later use;
(5) water of quoting that step (4) gained medicinal residues is added 8 times of weight decocted 1 hour again, and temperature is no more than 100 ℃, separation and Extraction liquid, pressure filtration, filtrate for later use;
(6) twice collected filtrate is merged, place in the vacuum evaporation concentrator, be decompressed to-300mmHg, be heated to 90 ℃, be concentrated into relative density and be 1.8 concentrated solution;
(7) thickening agent and the sweeting agent in the adding formula proportion fully stirs;
(8) spray drying forming under 70-80 ℃ of environment;
(9) granulate, sieve, packing, sterilization, quality inspection, packing, obtain the finished particle agent.
Usage: oral, each 1 to 2 bag, after washing open, warm water takes, and each 2 times, 7 days is a course for the treatment of, and be 1-2 visual effects the course for the treatment of usually.
The specific embodiment
Embodiment 1
Take by weighing major ingredient and adjuvant by following proportioning:
Major ingredient: 100 parts of leaf of Chimonanthus Nitens, 50 parts of Radix Isatidis, 30 parts of Flos Chrysanthemi Indicis, 10 parts of Herba Verbenae, 10 parts of Bombyx Batryticatus, 6 parts of Periostracum Cicadaes, 11 parts of the Rhizoma Anemarrhenaes, 8 parts of Herba Houttuyniae, 5 parts in Radix Glycyrrhizae, 8 parts of Herba Menthaes, 9 parts of Rhizoma Atractylodis, 3 parts of Herba Eupatoriis, 10 parts of Radix Saposhnikoviaes, 4 parts of Fructus Hordei Germinatus (parched to brown)s, 3 parts of Massa Medicata Fermentata (parched to brown), 2 parts of Fructus Crataegi (parched to brown)s, 10 parts of Endothelium Corneum Gigeriae Galli, 13 parts of Rhizoma Phragmitiss, 4 parts of Radix Paeoniae Rubra, 5 parts in Rhizoma Zingiberis Recens; 10 parts of Fructus Tritici Levis, 5 parts of Flos Trolliis, 12 parts of Radix Platycodoniss, 6 parts of Spica Prunellaes;
5 parts of thickening agents, 3 parts of sweeting agents.
(1) takes by weighing various medicinal raw materials by said ratio, and choose the removal of impurity with manual method;
(2) raw material of select is dried under 60 ℃ of environment, and use ultraviolet radiation disinfection;
(3) with disintegrating apparatus raw material is broken into powder about 80 orders and even blend;
(4) powder after the mixing of step (3) gained is poured in the extraction still, the decocting of quoting that adds 10 times of raw material weights boiled 2 hours, and temperature is no more than 100 ℃, separation and Extraction liquid, pressure filtration, filtrate for later use;
(5) water of quoting that step (4) gained medicinal residues is added 8 times of weight decocted 1 hour again, and temperature is no more than 100 ℃, separation and Extraction liquid, pressure filtration, filtrate for later use;
(6) twice collected filtrate is merged, place in the vacuum evaporation concentrator, be decompressed to-300mmHg, be heated to 90 ℃, be concentrated into relative density and be 1.8 concentrated solution;
(7) thickening agent and the sweeting agent in the adding formula proportion fully stirs;
(8) spray drying forming under 70 ℃ of environment;
(9) granulate, sieve, packing, sterilization, quality inspection, packing, obtain the finished particle agent.
Embodiment 2
Take by weighing major ingredient and adjuvant by following proportioning:
Major ingredient: 150 parts of leaf of Chimonanthus Nitens, 60 parts of Radix Isatidis, 50 parts of Flos Chrysanthemi Indicis, 15 parts of Herba Verbenae, 20 parts of Bombyx Batryticatus, 10 parts of Periostracum Cicadaes, 16 parts of the Rhizoma Anemarrhenaes, 15 parts of Herba Houttuyniae, 10 parts in Radix Glycyrrhizae, 12 parts of Herba Menthaes, 15 parts of Rhizoma Atractylodis, 7 parts of Herba Eupatoriis, 15 parts of Radix Saposhnikoviaes, 8 parts of Fructus Hordei Germinatus (parched to brown)s, 6 parts of Massa Medicata Fermentata (parched to brown), 5 parts of Fructus Crataegi (parched to brown)s, 20 parts of Endothelium Corneum Gigeriae Galli, 18 parts of Rhizoma Phragmitiss, 8 parts of Radix Paeoniae Rubra, 10 parts in Rhizoma Zingiberis Recens; 15 parts of Fructus Tritici Levis, 10 parts of Flos Trolliis, 16 parts of Radix Platycodoniss, 10 parts of Spica Prunellaes;
8 parts of sodium carboxymethyl cellulose, 5 parts of maltose.
(1) takes by weighing various medicinal raw materials by said ratio, and choose the removal of impurity with manual method;
(2) raw material of select is dried under 60 ℃ of environment, and use ultraviolet radiation disinfection;
(3) with disintegrating apparatus raw material is broken into powder about 80 orders and even blend;
(4) powder after the mixing of step (3) gained is poured in the extraction still, the decocting of quoting that adds 10 times of raw material weights boiled 2 hours, and temperature is no more than 100 ℃, separation and Extraction liquid, pressure filtration, filtrate for later use;
(5) water of quoting that step (4) gained medicinal residues is added 8 times of weight decocted 1 hour again, and temperature is no more than 100 ℃, separation and Extraction liquid, pressure filtration, filtrate for later use;
(6) twice collected filtrate is merged, place in the vacuum evaporation concentrator, be decompressed to-300mmHg, be heated to 90 ℃, be concentrated into relative density and be 1.8 concentrated solution;
(7) thickening agent and the sweeting agent in the adding formula proportion fully stirs;
(8) spray drying forming under 80 ℃ of environment;
(9) granulate, sieve, packing, sterilization, quality inspection, packing, obtain the finished particle agent.
Embodiment 3
Take by weighing major ingredient and adjuvant by following proportioning:
Major ingredient: 128 parts of leaf of Chimonanthus Nitens, 55 parts of Radix Isatidis, 45 parts of Flos Chrysanthemi Indicis, 12 parts of Herba Verbenae, 15 parts of Bombyx Batryticatus, 8 parts of Periostracum Cicadaes, 13 parts of the Rhizoma Anemarrhenaes, 11 parts of Herba Houttuyniae, 8 parts in Radix Glycyrrhizae, 10 parts of Herba Menthaes, 13 parts of Rhizoma Atractylodis, 5 parts of Herba Eupatoriis, 12 parts of Radix Saposhnikoviaes, 6 parts of Fructus Hordei Germinatus (parched to brown)s, 5 parts of Massa Medicata Fermentata (parched to brown), 3 parts of Fructus Crataegi (parched to brown)s, 12 parts of Endothelium Corneum Gigeriae Galli, 17 parts of Rhizoma Phragmitiss, 6 parts of Radix Paeoniae Rubra, 6 parts in Rhizoma Zingiberis Recens; 13 parts of Fructus Tritici Levis, 9 parts of Flos Trolliis, 14 parts of Radix Platycodoniss, 7 parts of Spica Prunellaes;
7 parts of starch, 4 parts in mannitol.Medicament processing method of the present invention is carried out as follows:
(1) takes by weighing various medicinal raw materials by said ratio, and choose the removal of impurity with manual method;
(2) raw material of select is dried under 60 ℃ of environment, and use ultraviolet radiation disinfection;
(3) with disintegrating apparatus raw material is broken into powder about 80 orders and even blend;
(4) powder after the mixing of step (3) gained is poured in the extraction still, the decocting of quoting that adds 10 times of raw material weights boiled 2 hours, and temperature is no more than 100 ℃, separation and Extraction liquid, pressure filtration, filtrate for later use;
(5) water of quoting that step (4) gained medicinal residues is added 8 times of weight decocted 1 hour again, and temperature is no more than 100 ℃, separation and Extraction liquid, pressure filtration, filtrate for later use;
(6) twice collected filtrate is merged, place in the vacuum evaporation concentrator, be decompressed to-300mmHg, be heated to 90 ℃, be concentrated into relative density and be 1.8 concentrated solution;
(7) thickening agent and the sweeting agent in the adding formula proportion fully stirs;
(8) spray drying forming under 75 ℃ of environment;
(9) granulate, sieve, packing, sterilization, quality inspection, packing, obtain the finished particle agent.
Claims (5)
1. the Chinese medicine granules that heat clearing away, treatment are caught a cold is characterized in that, is made up of following materials of weight proportions:
Major ingredient: leaf of Chimonanthus Nitens 100-150 part, Radix Isatidis 50-60 part, Flos Chrysanthemi Indici 30-50 part, Herba Verbenae 10-15 part, Bombyx Batryticatus 10-20 part, Periostracum Cicadae 6-10 part, Rhizoma Anemarrhenae 11-16 part, Herba Houttuyniae 8-15 part, Radix Glycyrrhizae 5-10 part, Herba Menthae 8-12 part, Rhizoma Atractylodis 9-15 part, Herba Eupatorii 3-7 part, Radix Saposhnikoviae 10-15 part, Fructus Hordei Germinatus (parched to brown) 4-8 part, Massa Medicata Fermentata (parched to brown) 3-6 part, Fructus Crataegi (parched to brown) 2-5 part, Endothelium Corneum Gigeriae Galli 10-20 part, Rhizoma Phragmitis 13-18 part, Radix Paeoniae Rubra 4-8 part, Rhizoma Zingiberis Recens 5-10 part; Fructus Tritici Levis 10-15 part, Flos Trollii 5-10 part, Radix Platycodonis 12-16 part, Spica Prunellae 6-10 part;
Thickening agent 5-8 part, described thickening agent are any one in starch, maltodextrin, hydroxypropyl cellulose, hydroxypropyl emthylcellulose, sodium carboxymethyl cellulose, the carboxymethyl starch sodium;
Sweeting agent 3-5 part: described sweeting agent is any one in sucrose, maltose, mannitol or the xylitol.
2. granule according to claim 1 is characterized in that, is made up of following materials of weight proportions:
Major ingredient; 100 parts of leaf of Chimonanthus Nitens, 50 parts of Radix Isatidis, 30 parts of Flos Chrysanthemi Indicis, 10 parts of Herba Verbenae, 10 parts of Bombyx Batryticatus, 6 parts of Periostracum Cicadaes, 11 parts of the Rhizoma Anemarrhenaes, 8 parts of Herba Houttuyniae, 5 parts in Radix Glycyrrhizae, 8 parts of Herba Menthaes, 9 parts of Rhizoma Atractylodis, 3 parts of Herba Eupatoriis, 10 parts of Radix Saposhnikoviaes, 4 parts of Fructus Hordei Germinatus (parched to brown)s, 3 parts of Massa Medicata Fermentata (parched to brown), 2 parts of Fructus Crataegi (parched to brown)s, 10 parts of Endothelium Corneum Gigeriae Galli, 13 parts of Rhizoma Phragmitiss, 4 parts of Radix Paeoniae Rubra, 5 parts in Rhizoma Zingiberis Recens; 10 parts of Fructus Tritici Levis, 5 parts of Flos Trolliis, 12 parts of Radix Platycodoniss, 6 parts of Spica Prunellaes;
5 parts of thickening agents, 3 parts of sweeting agents.
3. granule according to claim 1 is characterized in that, is made up of following materials of weight proportions:
Major ingredient: 150 parts of leaf of Chimonanthus Nitens, 60 parts of Radix Isatidis, 50 parts of Flos Chrysanthemi Indicis, 15 parts of Herba Verbenae, 20 parts of Bombyx Batryticatus, 10 parts of Periostracum Cicadaes, 16 parts of the Rhizoma Anemarrhenaes, 15 parts of Herba Houttuyniae, 10 parts in Radix Glycyrrhizae, 12 parts of Herba Menthaes, 15 parts of Rhizoma Atractylodis, 7 parts of Herba Eupatoriis, 15 parts of Radix Saposhnikoviaes, 8 parts of Fructus Hordei Germinatus (parched to brown)s, 6 parts of Massa Medicata Fermentata (parched to brown), 5 parts of Fructus Crataegi (parched to brown)s, 20 parts of Endothelium Corneum Gigeriae Galli, 18 parts of Rhizoma Phragmitiss, 8 parts of Radix Paeoniae Rubra, 10 parts in Rhizoma Zingiberis Recens; 15 parts of Fructus Tritici Levis, 10 parts of Flos Trolliis, 16 parts of Radix Platycodoniss, 10 parts of Spica Prunellaes;
8 parts of thickening agents, 5 parts of sweeting agents.
4. granule according to claim 1 is characterized in that, is made up of following materials of weight proportions:
Major ingredient: 128 parts of leaf of Chimonanthus Nitens, 55 parts of Radix Isatidis, 45 parts of Flos Chrysanthemi Indicis, 12 parts of Herba Verbenae, 15 parts of Bombyx Batryticatus, 8 parts of Periostracum Cicadaes, 13 parts of the Rhizoma Anemarrhenaes, 11 parts of Herba Houttuyniae, 8 parts in Radix Glycyrrhizae, 10 parts of Herba Menthaes, 13 parts of Rhizoma Atractylodis, 5 parts of Herba Eupatoriis, 12 parts of Radix Saposhnikoviaes, 6 parts of Fructus Hordei Germinatus (parched to brown)s, 5 parts of Massa Medicata Fermentata (parched to brown), 3 parts of Fructus Crataegi (parched to brown)s, 12 parts of Endothelium Corneum Gigeriae Galli, 17 parts of Rhizoma Phragmitiss, 6 parts of Radix Paeoniae Rubra, 6 parts in Rhizoma Zingiberis Recens; 13 parts of Fructus Tritici Levis, 9 parts of Flos Trolliis, 14 parts of Radix Platycodoniss, 7 parts of Spica Prunellaes;
7 parts of thickening agents, 4 parts of sweeting agents.
5. as the preparation method of granule as described among the claim 1-4 any, it is characterized in that, carry out according to following steps:
(1) takes by weighing various medicinal raw materials by said ratio, and choose the removal of impurity with manual method;
(2) raw material of select is dried under 60 ℃ of environment, and use ultraviolet radiation disinfection;
(3) with disintegrating apparatus raw material is broken into powder about 80 orders and even blend;
(4) powder after the mixing of step (3) gained is poured in the extraction still, the decocting of quoting that adds 10 times of raw material weights boiled 2 hours, and temperature is no more than 100 ℃, separation and Extraction liquid, pressure filtration, filtrate for later use;
(5) water of quoting that step (4) gained medicinal residues is added 8 times of weight decocted 1 hour again, and temperature is no more than 100 ℃, separation and Extraction liquid, pressure filtration, filtrate for later use;
(6) twice collected filtrate is merged, place in the vacuum evaporation concentrator, be decompressed to-300mmHg, be heated to 90 ℃, be concentrated into relative density and be 1.8 concentrated solution;
(7) thickening agent and the sweeting agent in the adding formula proportion fully stirs;
(8) spray drying forming under 70-80 ℃ of environment;
(9) granulate, sieve, packing, sterilization, quality inspection, packing, obtain the finished particle agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN 201210013661 CN102526665B (en) | 2012-01-17 | 2012-01-17 | Chinese medicinal particles for clearing heat, allaying fever and treating cold |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201210013661 CN102526665B (en) | 2012-01-17 | 2012-01-17 | Chinese medicinal particles for clearing heat, allaying fever and treating cold |
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| CN102526665A CN102526665A (en) | 2012-07-04 |
| CN102526665B true CN102526665B (en) | 2013-08-14 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103283863B (en) * | 2013-06-28 | 2014-06-11 | 叶建斌 | Bean curd capable of clearing away heat and toxic material and moistening lung and preparation method thereof |
| CN103550419B (en) * | 2013-11-13 | 2016-06-08 | 张笑飞 | Clearing away heat for children Chinese medicine |
| CN106237293A (en) * | 2016-08-31 | 2016-12-21 | 庄宏杰 | A kind of anemofrigid cold nursing Chinese medicine composition |
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2012
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| CN1840113A (en) * | 2006-01-23 | 2006-10-04 | 冯东 | Chinese medicinal preparation for treating viral influenza |
| CN101564514A (en) * | 2009-06-12 | 2009-10-28 | 杨文龙 | Method for analyzing children Fengreqing particle |
| CN101601830A (en) * | 2009-07-10 | 2009-12-16 | 卢速江 | A kind of Chinese medicine preparation for the treatment of flu and preparation method thereof |
| CN101698005A (en) * | 2009-11-25 | 2010-04-28 | 河南太龙药业股份有限公司 | Gold granules used for treating cold and influenza and preparation method thereof |
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