CN106880722A - It is a kind of to treat compound traditional Chinese medicine composite of rhinitis and preparation method thereof - Google Patents

It is a kind of to treat compound traditional Chinese medicine composite of rhinitis and preparation method thereof Download PDF

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CN106880722A
CN106880722A CN201510936032.7A CN201510936032A CN106880722A CN 106880722 A CN106880722 A CN 106880722A CN 201510936032 A CN201510936032 A CN 201510936032A CN 106880722 A CN106880722 A CN 106880722A
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rhinitis
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张维庆
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    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The present invention is proposed and a kind of treats compound traditional Chinese medicine composite of rhinitis and preparation method thereof, it is characterized in that being constituted using the kinds of traditional Chinese medicines such as mushroom, stir-baked FRUCCTUS XANTHII, Selaginella tamariscina, windproof, climbing groundsel, fructus viticis, cordate houttuynia, Centipeda minima, the flower bud of lily magnolia, the root of Dahurain angelica, Chinese yam, Radix Codonopsis, rhizoma atractylodis macrocephalae, barrenwort, starfish, with treatment nasal membrane inflammation, help lung, spleen, kidney deficiency, heat-clearing, removing toxic substances, analgesic, the effects such as enhancing human body resistance chill, the invasion and attack of wind-heat exopathogen, acute rhinitis, rhinitis chronic, allergic rhinitis and nasosinusitis can be effectively treated, and it is safe.

Description

It is a kind of to treat compound traditional Chinese medicine composite of rhinitis and preparation method thereof
Technical field
The present invention relates to pharmaceutical sanitary field, and in particular to a kind of to treat compound traditional Chinese medicine composite of rhinitis and preparation method thereof.
Background technology
Rhinitis belongs to common, multiple illness, data statistics shows that China's rhinitis incidence of disease is up to 37%, and the total crowd of patient is more than 500,000,000 people, it is nasal cavity inflammatory disease, is the inflammation of the bronchia mucosal that virus, bacterium, allergen, various physical and chemical factors and some systemic diseases cause.The main pathological change of rhinitis is bronchia mucosal hyperemia, swelling, ooze out, hyperplasia, atrophy or necrosis etc..Rhinitis including acute rhinitis, rhinitis chronic, allergic rhinitis etc., wherein:Acute rhinitis is also called " cold ", and it is the acute disease of nasal membrane, the respiratory inflammation such as concurrent throat and tracheae often of falling ill;Rhinitis chronic is the chronic inflammation of a kind of common nasal membrane and submucosa, and clinic is cardinal symptom to have a stuffy nose, and this disease is formed by acute rhinitis recurrent exerbation or without appropriate treatment delay more, caused by the traditional Chinese medical science thinks this disease mainly because of lung, Spleen-Qi Deficiency;Allergic rhinitis, also known as " allergic rhinitis ", is that the people of some special constitutions contacts the abnormal response that Cucumber occurs.Traditional Chinese medicine thinks that the pathogensis of rhinitis have four:1. insufficiency of lung-QI, affection by exopathogenic cold-wind;2. asthenia of pulmonosplenic qi, the wet general nose of water;3. kidney qi virtual loss, lung loses gentle;4. lung channel is hot and suffocating, is attacked outside wind-heat.Although at present in treatment rhinitis, western drug is more, many medicines exist curative effect not substantially or toxic and side effect it is larger or in-convenience in use the shortcomings of, therefore clinic is in the urgent need to a kind of determined curative effect, anti-rhinitis medicament thing safe, easy to use.
The content of the invention
In view of above-mentioned the deficiencies in the prior art, it is an object of the invention to provide a kind of effective treatment acute or chronic rhinitis and allergic rhinitis, the compound traditional Chinese medicine composite of nasosinusitis.
The present invention is realized by the following technical programs:
The Chinese traditional compound medicine for the treatment of rhinitis of the present invention, is prepared from by the raw material of following weight proportion:
Mushroom 10-1000 parts, stir-baked FRUCCTUS XANTHII 10-100 parts, Selaginella tamariscina 10-100 parts, it is windproof 10-100 parts, climbing groundsel 5-50 parts, fructus viticis 10-100 parts, cordate houttuynia 10-100 parts, Centipeda minima 10-100 parts, flower bud of lily magnolia 10-100 parts, root of Dahurain angelica 10-100 parts, Chinese yam 10-100 parts, Radix Codonopsis 10-100 parts, rhizoma atractylodis macrocephalae 10-100 parts, barrenwort 10-100 parts, starfish 5-50 parts.
Preferably, it is to be prepared from by the raw material containing following weight proportion:
200 parts of mushroom, 30 parts of stir-baked FRUCCTUS XANTHII, 20 parts of Selaginella tamariscina, windproof 20 parts, 10 parts of climbing groundsel, 20 parts of fructus viticis, 10 parts of cordate houttuynia, 10 parts of Centipeda minima, 10 parts of the flower bud of lily magnolia, 20 parts of the root of Dahurain angelica, 20 parts of Chinese yam, 20 parts of Radix Codonopsis, 20 parts of rhizoma atractylodis macrocephalae, 20 parts of barrenwort, 10 parts of starfish.
Preferably, it is to be prepared from by the raw material containing following weight proportion:
100 parts of mushroom, 30 parts of stir-baked FRUCCTUS XANTHII, 10 parts of Selaginella tamariscina, windproof 20 parts, 10 parts of climbing groundsel, 20 parts of fructus viticis, 10 parts of cordate houttuynia, 10 parts of Centipeda minima, 10 parts of the flower bud of lily magnolia, 20 parts of the root of Dahurain angelica, 20 parts of Chinese yam, 10 parts of Radix Codonopsis, 20 parts of rhizoma atractylodis macrocephalae, 10 parts of barrenwort, 10 parts of starfish.
The pharmaceutical characteristic of each raw material of the present invention is:
Mushroom, indication:QI invigorating is not hungry, control wind blood-breaking, phlegm-eliminiating and qi-regulating, beneficial taste help food, prevent the various mucous membranes of human body and scytitis, prevent physical decline, capillary rupture etc., while mushroom has the effects such as detoxify, antiviral, regulation is immune.
The achene of Siberian cocklebur, indication:Dissipate wind dehumidifying, clearing the nasal passage;For anemofrigid headache, nasosinusitis runny nose, rubella itch, arthritis with fixed pain caused by dampness contraction;Modern pharmacy research simultaneously finds that the achene of Siberian cocklebur can substantially suppress murine heterotropic passive cutaneous anaphylaxis.
Selaginella tamariscina, indication:Invigorate blood circulation;For closed dysmenorrhea , wei lump in the abdomen lump in the abdomens, injury from falling down;Modern pharmacy research simultaneously finds that Selaginella tamariscina can substantially suppress murine heterotropic passive cutaneous anaphylaxis.
It is windproof, indication:Inducing diaphoresis to dispel wind, wins wet, only convulsion;For cold headache, arthralgia pain due to rheumatism, rubella itch, lockjaw;Modern medicine and pharmacology research simultaneously shows that windproof decoction, preserved material have obvious refrigeration function, and have anti-inflammatory and anticonvulsant action, also strengthens immune and anti-allergic effects.
Climbing groundsel, indication:Clearing heat and detoxicating, cool blood detumescence is clear liver and improved vision;Can be used to treat various acute inflammatory diseases, wind fire cute conjunctivitis, mesh screen, typhoid fever, bacillary dysentery, lobar pneumonia, tonsillitis, enteritis, jaundice, anemopyretic cold etc.;Modern pharmacy research simultaneously finds that climbing groundsel can substantially suppress murine heterotropic passive cutaneous anaphylaxis.
Fructus viticis, indication:Dispelling wind and heat from the body, head clearing;For anemopyretic cold headache, gingivitis, many tears of hot eyes, mesh is secretly failed to understand, is had a dizzy spell.
Cordate houttuynia, indication:It is clearing heat and detoxicating, the carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia;For lung carbuncle pyemesis, phlegm heat panting is coughed, hot dysentery, heat gonorrhea, carbuncle sore tumefacting virus.
Centipeda minima, indication:Clearing the nasal passage, cough-relieving;For anemofrigid headache, coughing with a lot of sputum, obstructed, nasosinusitis runny nose of having a stuffy nose.
The flower bud of lily magnolia, indication:Dispersing wind and cold, clearing the nasal passage;For anemofrigid headache, nasal obstruction, nasosinusitis, turbid nasal discharge.
The root of Dahurain angelica, indication:Wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving;For having a headache, having a toothache, nasosinusitis,
Ulcer sores, pruitus etc.;Modern medicine and pharmacology research simultaneously shows that the root of Dahurain angelica has the pharmacological actions such as anti-inflammatory, antibacterial, antipyretic-antalgic.
Chinese yam, indication:Tonifying spleen nourishing the stomach, engender liquid and benefic lung, the puckery essence of kidney tonifying;For spleen eating less, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, and emission due to the kidney deficiency, under band, frequent micturition, abnormal heat is quenched one's thirst.
Radix Codonopsis, indication:Tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung;For spleen and lung weakness, shortness of breath palpitations, anorexia and loose stool, virtual asthma cough, Heat Diabetes.
Rhizoma atractylodis macrocephalae, indication:Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis is antiabortive;For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema etc..
Barrenwort, indication:Kidney-replenishing, strengthening the bones and muscles, wind-damp dispelling;For impotence and seminal emission, muscles and bones impotence, arthralgia pain due to rheumatism etc..
Starfish, indication:Detoxicating and resolving a mass, and stomach and alleviating pain, for Thyroid Gland Swell, scrofula, pantothenic acid of having a stomachache, diarrhoea, tympanitis;Modern pharmacy research simultaneously finds that starfish has obvious yang invigorating functions.
The main ingredient of compound traditional Chinese medicine composite of the invention is mushroom, and mushroom is with the effect for preventing and treating skin and mucosa inflammation, and the inflammation of rhinitis exactly bronchia mucosal, therefore mushroom can symptomatic treatment rhinitis;Stir-baked FRUCCTUS XANTHII in side has the effects such as treatment nasosinusitis runny nose, anemofrigid headache, and can substantially suppress cutaneous anaphylaxis, and stir-baked FRUCCTUS XANTHII is made after the achene of Siberian cocklebur is processed, and significantly reduces the drug toxicity, and security is higher;Selaginella tamariscina, climbing groundsel etc. also have the effect for substantially suppressing cutaneous anaphylaxis, have therapeutic action to allergic rhinitis;Fructus viticis, cordate houttuynia etc. have clearing heat and detoxicating, can treat anemopyretic cold, have a headache, the disease such as have a dizzy spell;Centipeda minima, flower bud of lily magnolia etc. can treat anemofrigid cold, headache, obstructed, the disease such as nasosinusitis runny nose of having a stuffy nose;It is windproof with treatment cold headache, and anti-inflammatory, the effect such as antiallergy;Chinese yam, Radix Codonopsis, rhizoma atractylodis macrocephalae etc. are with help is insufficiency of the spleen and effect of the deficiency syndrome of the lung;Barrenwort, starfish etc. have the effect such as warming and invigorating kidney deficiency.By above medicament composing prescription, body antianaphylaxis can be strengthened, eliminate nasal cavity and respiratory inflammation, there is heat-clearing, removing toxic substances, analgesic simultaneously, body immunity, enhancing spleen, lung, renal function is adjusted, the effects such as enhancing human body resistance chill, the invasion and attack of wind-heat exopathogen, therefore can symptomatic treatment is acute, rhinitis chronic, and allergic rhinitis, nasosinusitis, and safe.
A kind of compound traditional Chinese medicine composite for treating rhinitis, its preparation method is comprised the following steps:
1st, mushroom, Chinese yam, starfish etc. are taken according to weight portion to clean, drying is ground into fine powder, transfer container is loaded as standby powder after crossing 100-120 mesh sieves.
2nd, according to weight portion take the achene of Siberian cocklebur, Centipeda minima, Selaginella tamariscina, windproof, fructus viticis, cordate houttuynia, the flower bud of lily magnolia, the root of Dahurain angelica, Radix Codonopsis, the bighead atractylodes rhizome, barrenwort etc. add Chinese medicine extracting tank in, extract said medicine liquid, and will after the concentration of liquid medicine be obtained condensed cream.
3rd, after being sufficiently mixed standby powder and condensed cream, it is combined with other auxiliary materials or packaging material, the Chinese medicine preparation of various formulations can be obtained.
The compound traditional Chinese medicine composite for the treatment of rhinitis of the present invention, can be combined with other auxiliary materials or packaging material, be made the medicine preparation of various formulations, including but not limited to:Tablet, capsule, soft capsule, pill, granule, powder, paste, syrup, decoction, tincture, nasal drop, oral administration solution etc..
Specific embodiment
The present invention is further illustrated by embodiment.It should be appreciated that specific embodiment described herein is only used for explaining the present invention, rather than limitation of the present invention.
Embodiment 1
Chinese traditional compound medicine of the invention, comprises the following steps and is prepared.
Step one:The taste medicinal material of mushroom, starfish, Chinese yam etc. 3 is taken by weight, is cleaned with pure water, drying is ground into fine powder using high speed Universal pulverizer, standby powder is obtained after crossing 120 mesh sieves, be fitted into standby in transfer container;
Step 2:Stir-baked FRUCCTUS XANTHII, Selaginella tamariscina, windproof, climbing groundsel, fructus viticis, cordate houttuynia, Centipeda minima, the flower bud of lily magnolia, the root of Dahurain angelica, Radix Codonopsis, rhizoma atractylodis macrocephalae, barrenwort are taken by weight, in addition Chinese medicine extracting tank, extracted 3 times with 30% alcohol reflux, each ethanol consumption is respectively 8 times, 6 times, 4 times of medicinal material total amount, extraction time is respectively 3 hours, 2 hours, 1 hour, merge extract solution, filtering is obtained filtered fluid;
Step 3:Filtered fluid is poured into condensed cream is extracted in concentration tank;
Step 4:The standby powder is sufficiently mixed with condensed cream, dry extract is obtained;
Step 5:Dry extract, auxiliary material etc. are crushed through Universalpulverizer, extract powder is obtained;
Step 6:It is sufficiently mixed during extract powder is added into mixer;
Step 7:Extract powder is dried, medicinal powder is obtained after crossing 120 mesh sieves;
Step 8:Medicinal powder is fitted into capsule through Autocapsulefillingmachine, herbal mixture capsule of the invention is obtained.
By herbal mixture capsule of the invention, choose 60 volunteers with acute rhinitis, rhinitis chronic, allergic rhinitis and nasosinusitis, exclude gout and to mushroom allergy sufferers, carry out clinical observation on the therapeutic effect, wherein, patients with mild takes a course for the treatment of, in, severe patient is continuous takes two to three courses for the treatment of and can obtain the curative effect of satisfaction.Specifically treatment results are:Fully recover 50 people(83.3%), effective 6 people(10.0%), effective 3 people(5%), invalid 1 people(1.7%), total effective rate is up to 98.3%.
It should be understood that; preference of the invention and embodiment are not limited only to above-mentioned citing; it will be apparent to those skilled in the art that can be improved or converted according to foregoing invention, all these modifications and variations should be all included within the scope of rights protection requirement appended by the present invention.

Claims (5)

1. a kind of compound traditional Chinese medicine composite for treating rhinitis, it is characterised in that:It is to be prepared from the following raw materials in parts by weight:Mushroom 10-1000 parts, stir-baked FRUCCTUS XANTHII 10-100 parts, Selaginella tamariscina 10-100 parts, it is windproof 10-100 parts, climbing groundsel 5-50 parts, fructus viticis 10-100 parts, cordate houttuynia 10-100 parts, Centipeda minima 10-100 parts, flower bud of lily magnolia 10-100 parts, root of Dahurain angelica 10-100 parts, Chinese yam 10-100 parts, Radix Codonopsis 10-100 parts, rhizoma atractylodis macrocephalae 10-100 parts, barrenwort 10-100 parts, starfish 5-50 parts.
2. a kind of compound traditional Chinese medicine composite for treating rhinitis according to claim 1, it is characterised in that:It is to be prepared from the following raw materials in parts by weight:200 parts of mushroom, 30 parts of stir-baked FRUCCTUS XANTHII, 20 parts of Selaginella tamariscina, windproof 20 parts, 10 parts of climbing groundsel, 20 parts of fructus viticis, 10 parts of cordate houttuynia, 10 parts of Centipeda minima, 10 parts of the flower bud of lily magnolia, 20 parts of the root of Dahurain angelica, 20 parts of Chinese yam, 20 parts of Radix Codonopsis, 20 parts of rhizoma atractylodis macrocephalae, 20 parts of barrenwort, 10 parts of starfish.
3. a kind of compound traditional Chinese medicine composite for treating rhinitis according to claim 1, it is characterised in that:It is made up of the raw material of following weight proportion:100 parts of mushroom, 30 parts of stir-baked FRUCCTUS XANTHII, 20 parts of Selaginella tamariscina, windproof 20 parts, 10 parts of climbing groundsel, 20 parts of fructus viticis, 10 parts of cordate houttuynia, 10 parts of Centipeda minima, 10 parts of the flower bud of lily magnolia, 20 parts of the root of Dahurain angelica, 20 parts of Chinese yam, 20 parts of Radix Codonopsis, 20 parts of rhizoma atractylodis macrocephalae, 20 parts of barrenwort, 10 parts of starfish.
4. a kind of preparation method of the compound traditional Chinese medicine composite for treating rhinitis, it is characterised in that:According to the Chinese medicine composition any one of claim 1-3, it is characterised in that its active component is prepared by the following method and forms:Take mushroom, Chinese yam, starfish etc. clean, drying after wear into fine powder, load transfer container as standby powder after crossing 100-120 mesh sieves, take stir-baked FRUCCTUS XANTHII, Selaginella tamariscina, windproof, climbing groundsel, fructus viticis, cordate houttuynia, Centipeda minima, the flower bud of lily magnolia, the root of Dahurain angelica, Radix Codonopsis, rhizoma atractylodis macrocephalae, barrenwort etc., in addition Chinese medicine extracting tank, extract the liquid of said medicine, and condensed cream will be obtained after the concentration of liquid medicine, after standby powder and condensed cream are sufficiently mixed, obtain final product the active component.
5. the Chinese medicine composition of the treatment rhinitis of any one of a kind of Chinese medicine for treating rhinitis composition, including claim 1-3 and acceptable carrier in pharmaceuticals industry.
CN201510936032.7A 2015-12-15 2015-12-15 It is a kind of to treat compound traditional Chinese medicine composite of rhinitis and preparation method thereof Pending CN106880722A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107582708A (en) * 2017-09-22 2018-01-16 简惠泉 A kind of Chinese traditional medicine composition preparation for preventing and treating rhinitis and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107582708A (en) * 2017-09-22 2018-01-16 简惠泉 A kind of Chinese traditional medicine composition preparation for preventing and treating rhinitis and preparation method thereof

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