CN105194419A - Anti-influenza Chinese herbal medicine composition - Google Patents
Anti-influenza Chinese herbal medicine composition Download PDFInfo
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- CN105194419A CN105194419A CN201510744503.4A CN201510744503A CN105194419A CN 105194419 A CN105194419 A CN 105194419A CN 201510744503 A CN201510744503 A CN 201510744503A CN 105194419 A CN105194419 A CN 105194419A
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- influenza virus
- radix
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- resisiting influenza
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Abstract
The invention discloses anti-influenza Chinese herbal medicine composition. The anti-influenza Chinese herbal medicine composition comprises components of raw materials in parts by weight as follows: 12-30 parts of screwtree roots, 6-15 parts of sweet wormwood, 5-15 parts of mulberry leaves, 2-6 parts of lalang grass rhizome, 6-15 parts of snake bramble seeds, 3-8 parts of scutellaria baicalensis and 3-8 parts of uniflower swisscentaury roots. The anti-influenza Chinese herbal medicine composition adopts natural Chinese herbs as the raw materials, is not added with any additives, has a unique curative effect on influenza virus and a fast curative effect on symptoms of fever, headache, bodily pain, pharyngalgia, cough and asthma caused by the influenza virus and does not have side effects on the human body.
Description
Technical field
The present invention relates to a kind of resisiting influenza virus herbal composite.
Background technology
Influenza (Influenza) is a kind of Acute respiratory infectious disease caused by influenza virus, and infectiousness is strong, and sickness rate is high.Eighties of last century 4 large-scale influenza virus have attacked the mankind, bring very grave disaster.After entering new century, H5N1 Human avian flu virus and influenza A H1N1 influenza virus popular, brings great harm to the mankind.In recent years influenza have Epidemic Scope wide, propagate fast, the cycle is long, the easy feature such as recurrence after drug withdrawal, brings huge difficulty to preventing and treating.Safety, efficiently Tamiflu receive much concern in medical circle.Virus is the biology that nature is small, and through the research progress in more than 100 years of the mankind, the mankind progressively disclose characteristic and viruses and man, the natural mutual relation of virus.But, the mankind are still little to the understanding of virus, to natural boundary treaty 5,000 kinds viral 95%, still know nothing.This is mainly because the variability of virus allows mankind's unpredictable.Widely using of existing chemicals, make influenza virus create drug resistance, therapeutic effect is unsatisfactory, also can have side effects to human body.
Summary of the invention
The object of this invention is to provide a kind of resisiting influenza virus herbal composite, the present invention adopts natural Chinese medicinal herb as raw material, do not add any additive, infected by influenza has unique curative effect, the heating that infected by influenza causes, headache, general pain, pharyngalgia, cough, asthma therapy effect rapidly, have no side effect to human body.Technical scheme provided by the invention is:
A kind of resisiting influenza virus herbal composite, it is characterized in that, its raw material components is counted by weight and is comprised: Radix Helicteris 12-30 part, Herba Artemisiae Annuae 6-15 part, Folium Mori 5-15 part, Rhizoma Imperatae 2-6 part, Semen Caesalpiniae Minacis 6-15 part, Radix Scutellariae 3-8 part, Radix Rhapontici 3-8 part.
Preferably, in resisiting influenza virus herbal composite, described Radix Helicteris is serration Radix Helicteris.
Preferably, in resisiting influenza virus herbal composite, described Rhizoma Imperatae is the Rhizoma Imperatae of removing fibrous root and film quality sheath.
Preferably, in resisiting influenza virus herbal composite, described Folium Mori select growth 1 year diameter to be the Folium Mori that the branch of 1.5-2cm grows.
Preferably, in resisiting influenza virus herbal composite, described Semen Caesalpiniae Minacis adopts diameter 0.7-1.2cm, and surperficial corvinus is glossy, the Semen Caesalpiniae Minacis of visible horizontal ring grain or transverse crack.
A preparation method for resisiting influenza virus herbal composite, comprises the following steps:
Thinly slice after Rhizoma Imperatae and Radix Scutellariae warm water are cleaned 2-3 time, mix to put into Radix Helicteris, Herba Artemisiae Annuae, Folium Mori, Semen Caesalpiniae Minacis and Radix Rhapontici again and grind vessel, add after pulverizing after wanting the soak by water 40-60 of medicated powder amount 10 times minute and obtain extracting solution, after extracting solution is down to room temperature, the ethanol adding 95% stirs, leave standstill and make solution precipitation 20-30 minute, the ethanol adding 75% again continues to staticly settle 20-30 minute, pour out supernatant, make extractum by concentrated for precipitate, put into Refrigerator store for subsequent use.
Technical scheme of the present invention comparatively prior art has outstanding advantages the present invention to adopt natural Chinese medicinal herb as raw material, do not add any additive, infected by influenza has unique curative effect, the heating that infected by influenza causes, headache, general pain, pharyngalgia, cough, asthma therapy effect rapidly, have no side effect to human body.
Detailed description of the invention
Below in conjunction with embodiment, description is remake to the present invention, but should not limit the scope of the invention with this.
Embodiment one
A kind of resisiting influenza virus herbal composite, it is characterized in that, its raw material components is counted by weight and is comprised: Radix Helicteris 12 parts, Herba Artemisiae Annuae 6 parts, 5 parts, Folium Mori, Rhizoma Imperatae 2 parts, Semen Caesalpiniae Minacis 6 parts, Radix Scutellariae 3 parts, Radix Rhapontici 3 parts.Wherein Radix Helicteris is serration Radix Helicteris, and Rhizoma Imperatae is the Rhizoma Imperatae of removing fibrous root and film quality sheath, and Folium Mori select growth 1 year diameter to be the Folium Mori that the branch of 1.5-2cm grows, Semen Caesalpiniae Minacis adopts diameter 0.7-1.2cm, surface corvinus, glossy, the Semen Caesalpiniae Minacis of visible horizontal ring grain or transverse crack.
The preparation method of this resisiting influenza virus herbal composite is: thinly slice after Rhizoma Imperatae and Radix Scutellariae warm water are cleaned 2-3 time, again with Radix Helicteris, Herba Artemisiae Annuae, Folium Mori, grinding vessel are put in Semen Caesalpiniae Minacis and Radix Rhapontici mixing, add after pulverizing after wanting the soak by water 40-60 of medicated powder amount 10 times minute and obtain extracting solution, after extracting solution is down to room temperature, the ethanol adding 95% stirs, leave standstill and make solution precipitation 20-30 minute, the ethanol adding 75% again continues to staticly settle 20-30 minute, pour out supernatant, extractum is made by concentrated for precipitate, put into Refrigerator store for subsequent use.
Embodiment two
A kind of resisiting influenza virus herbal composite, it is characterized in that, its raw material components is counted by weight and is comprised: Radix Helicteris 30 parts, Herba Artemisiae Annuae 13 parts, 8 parts, Folium Mori, Rhizoma Imperatae 5 parts, Semen Caesalpiniae Minacis 10 parts, Radix Scutellariae 5 parts, Radix Rhapontici 5 parts.Wherein Radix Helicteris is serration Radix Helicteris, and Rhizoma Imperatae is the Rhizoma Imperatae of removing fibrous root and film quality sheath, and Folium Mori select growth 1 year diameter to be the Folium Mori that the branch of 1.5-2cm grows, Semen Caesalpiniae Minacis adopts diameter 0.7-1.2cm, surface corvinus, glossy, the Semen Caesalpiniae Minacis of visible horizontal ring grain or transverse crack.
The preparation method of this resisiting influenza virus herbal composite is: thinly slice after Rhizoma Imperatae and Radix Scutellariae warm water are cleaned 2-3 time, again with Radix Helicteris, Herba Artemisiae Annuae, Folium Mori, grinding vessel are put in Semen Caesalpiniae Minacis and Radix Rhapontici mixing, add after pulverizing after wanting the soak by water 40-60 of medicated powder amount 10 times minute and obtain extracting solution, after extracting solution is down to room temperature, the ethanol adding 95% stirs, leave standstill and make solution precipitation 20-30 minute, the ethanol adding 75% again continues to staticly settle 20-30 minute, pour out supernatant, extractum is made by concentrated for precipitate, put into Refrigerator store for subsequent use.
Embodiment three
A kind of resisiting influenza virus herbal composite, it is characterized in that, its raw material components is counted by weight and is comprised: Radix Helicteris 30 parts, Herba Artemisiae Annuae 15 parts, 15 parts, Folium Mori, Rhizoma Imperatae 6 parts, Semen Caesalpiniae Minacis 15 parts, Radix Scutellariae 8 parts, Radix Rhapontici 8 parts wherein Radix Helicteris is serration Radix Helicteris, Rhizoma Imperatae is the Rhizoma Imperatae of removing fibrous root and film quality sheath, Folium Mori select growth 1 year diameter to be the Folium Mori that the branch of 1.5-2cm grows, and Semen Caesalpiniae Minacis adopts diameter 0.7-1.2cm, surperficial corvinus, glossy, the Semen Caesalpiniae Minacis of visible horizontal ring grain or transverse crack.
The preparation method of this resisiting influenza virus herbal composite is: thinly slice after the Rhizoma Imperatae of above-mentioned components by weight percent and Radix Scutellariae warm water are cleaned 2-3 time, again with Radix Helicteris, Herba Artemisiae Annuae, Folium Mori, grinding vessel are put in Semen Caesalpiniae Minacis and Radix Rhapontici mixing, add after pulverizing after wanting the soak by water 40-60 of medicated powder amount 10 times minute and obtain extracting solution, after extracting solution is down to room temperature, the ethanol adding 95% stirs, leave standstill and make solution precipitation 20-30 minute, the ethanol adding 75% again continues to staticly settle 20-30 minute, pour out supernatant, extractum is made by concentrated for precipitate, put into Refrigerator store for subsequent use.
Adopt CPE method research performation example 1, embodiment 2 and embodiment 3 herbal composite are to the inhibitory action of influenza Alphavirus: by MD-CK cell by 2 × 10
6/ mL is inoculated in 96 well culture plates, and 200 μ L/ holes, at 5%CO
2, 37 DEG C cultivate 24h, add variable concentrations sample and RBV, establish cell controls simultaneously, continue to cultivate 48h, observation of cell lesion degree, adopt Reed-Muench method to calculate the half toxic concentration (TC of medicine
50) and maximal non-toxic concentration (TC
50).By mdck cell by 4 × 10
6/ mL is inoculated in 96 well culture plates, and 100 μ L/ holes, at 5%CO
2, 37 DEG C cultivate 24h.Add influenza Alphavirus 0.2 × 10
-4(93 × TCID
50), 100 μ L/ holes, 37 DEG C of absorption 2h, abandon virus liquid, add variable concentrations sample and RBV respectively.Establish cell normal control and virus control, 24h observation of cell lesion degree simultaneously, adopt Reed-Muench method to calculate the half-inhibition concentration (IG of medicine
50), and in conjunction with result meter drug therapeutic indices (TreatmentIndex, TI=TC50/IC50) of cell toxicity test.Result shows below:
The herbal composite of table 1 embodiment 1,2,3 is to anti-influenza A virus determination of activity result
Result shows, and the herbal composite of embodiment 1,2,3 has obvious inhibitory action to influenza Alphavirus in vitro.
Although working of an invention scheme is open as above, but it is not restricted to listed in description and embodiment utilization, it can be applied to various applicable the field of the invention completely, for those skilled in the art, can easily realize other amendment, therefore do not deviating under the general concept that claim and equivalency range limit, the present invention is not limited to specific details and illustrates here and the proportioning example described.
Claims (6)
1. a resisiting influenza virus herbal composite, is characterized in that, its raw material components is counted by weight and comprised: Radix Helicteris 12-30 part, Herba Artemisiae Annuae 6-15 part, Folium Mori 5-15 part, Rhizoma Imperatae 2-6 part, Semen Caesalpiniae Minacis 6-15 part, Radix Scutellariae 3-8 part, Radix Rhapontici 3-8 part.
2. resisiting influenza virus herbal composite as claimed in claim 1, it is characterized in that, described Radix Helicteris is serration Radix Helicteris.
3. resisiting influenza virus herbal composite as claimed in claim 1, is characterized in that, described Rhizoma Imperatae is the Rhizoma Imperatae of removing fibrous root and film quality sheath.
4. resisiting influenza virus herbal composite as claimed in claim 1, it is characterized in that, described Folium Mori select growth 1 year diameter to be the Folium Mori that the branch of 1.5-2cm grows.
5. resisiting influenza virus herbal composite as claimed in claim 1, is characterized in that, described Semen Caesalpiniae Minacis adopts diameter 0.7-1.2cm, and surperficial corvinus is glossy, the Semen Caesalpiniae Minacis of visible horizontal ring grain or transverse crack.
6. a preparation method for resisiting influenza virus herbal composite, is characterized in that, comprises the following steps:
Thinly slice after Rhizoma Imperatae and Radix Scutellariae warm water are cleaned 2-3 time, mix to put into Radix Helicteris, Herba Artemisiae Annuae, Folium Mori, Semen Caesalpiniae Minacis and Radix Rhapontici again and grind vessel, add after pulverizing after wanting the soak by water 40-60 of medicated powder amount 10 times minute and obtain extracting solution, after extracting solution is down to room temperature, the ethanol adding 95% stirs, leave standstill and make solution precipitation 20-30 minute, the ethanol adding 75% again continues to staticly settle 20-30 minute, pour out supernatant, make extractum by concentrated for precipitate, put into Refrigerator store for subsequent use.
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| CN201510744503.4A CN105194419B (en) | 2015-11-05 | 2015-11-05 | Resisiting influenza virus herbal composite |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107279501A (en) * | 2017-08-04 | 2017-10-24 | 哈尔滨千合动物药品制造有限公司 | A kind of feed for animals with resisiting influenza virus and preparation method thereof |
| CN115463125A (en) * | 2022-08-26 | 2022-12-13 | 高州市人民医院 | Application of 5-methoxyflavone in preparation of medicine for preventing or treating influenza virus infection |
-
2015
- 2015-11-05 CN CN201510744503.4A patent/CN105194419B/en active Active
Non-Patent Citations (1)
| Title |
|---|
| 广西侗族自治区中医药研究所: "《广西中医验方选集》", 31 July 1961, 广西侗族自治区人民出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107279501A (en) * | 2017-08-04 | 2017-10-24 | 哈尔滨千合动物药品制造有限公司 | A kind of feed for animals with resisiting influenza virus and preparation method thereof |
| CN115463125A (en) * | 2022-08-26 | 2022-12-13 | 高州市人民医院 | Application of 5-methoxyflavone in preparation of medicine for preventing or treating influenza virus infection |
| CN115463125B (en) * | 2022-08-26 | 2024-01-26 | 高州市人民医院 | Application of 5-methoxy flavone in preparing medicine for preventing or treating influenza virus infection |
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| CN105194419B (en) | 2019-03-12 |
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