CN107279501A - A kind of feed for animals with resisiting influenza virus and preparation method thereof - Google Patents
A kind of feed for animals with resisiting influenza virus and preparation method thereof Download PDFInfo
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- CN107279501A CN107279501A CN201710658529.6A CN201710658529A CN107279501A CN 107279501 A CN107279501 A CN 107279501A CN 201710658529 A CN201710658529 A CN 201710658529A CN 107279501 A CN107279501 A CN 107279501A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
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Abstract
The invention discloses a kind of feed formula for animals with resisiting influenza virus and manufacture craft, the formula is made up of the raw material of following parts by weight：Screwtree root, sweet wormwood, mulberry leaf, rhizoma imperatae, whiteflower cacalia seed, radix scutellariae, Radix Rhapontici seu Radix Echinopsis, corn flour, wheat flour, bean cake powder, fish meal, soybean oil, additive A, whey powder, white granulated sugar, calcium powder, calcium monohydrogen phosphate, compound amino acid, B B-complex part and additive B part；Preparation method of the present invention comprises the following steps：Sorting, dispensing, concentration cream processed, preparing raw material T, preparing raw material B and mixing curing；Infected by influenza of the present invention has the curative effect of uniqueness, treatment for diseases effect is rapid caused by infected by influenza, have no side effect, simultaneously using four curing processes in the preparation process of feed, feed is set to become crisp soft, increase palatability, while reducing ANFs and harmful microbe content in raw material, be easy to promote the growth of beasts.
Description
Technical field
The present invention relates to field of feed for animals, specially a kind of feed for animals and making work with resisiting influenza virus
Skill.
Background technology
Influenza (Influenza) is a kind of Acute respiratory infectious disease as caused by influenza virus, and infectiousness is strong, the incidence of disease
Height, at present, the feed product for animals sold on the market are that single formula, i.e. raw material are mixed with heat sensitive vitamins, enzyme preparation
A high temperature modulation curing is carried out afterwards, and temperature is 75~85 DEG C, and the modulation time is 15~25s.But the wherein curing degree of alphalise starch
Only 18~25%, sterilization ratio is only 6~15%, and vitamin destruction ratio is up to more than 20%.It can be seen that, it is existing formula and
The curing degree of the feed for animals of preparation technology production is low, and nutriment loss is more, and harmful microorganism and ANFs are abolished
It is not thorough.Cause that the palatability of feed is poor, transformation efficiency is low, while the function without anti influenza.
So, how to design a kind of feed for animals with resisiting influenza virus, the problem of currently being solved as us.
The content of the invention
The present invention provides a kind of feed for animals with resisiting influenza virus and preparation method thereof, simple production process, cost
It is cheap, easy to use, have no toxic side effect, not only with antiviral functions, while good health-care effect can be played to domestic animal, can
Low with the curing degree for effectively solving feed for animals, nutriment loss is more, and harmful microorganism and ANFs abolish not thorough
The problem of bottom.
To achieve the above object, the present invention provides following technical scheme：A kind of feed for animals with resisiting influenza virus, institute
Feed for animals is stated to be made up of the raw material of following parts by weight：12~30 parts of screwtree root, 6~15 parts of sweet wormwood, 5~15 parts of mulberry leaf, cogongrass
2~6 parts of root, 6~15 parts of whiteflower cacalia seed, 3~8 parts of radix scutellariae, 3~8 parts of Radix Rhapontici seu Radix Echinopsis, 55~60 parts of corn flour, 15~20 parts of wheat flour, beans
15~20 parts of dregs of rice powder, 2~3 parts of fish meal, 2~3 parts of soybean oil, 1~4 part of additive A, 8~10 parts of whey powder, white granulated sugar 1~2
Part, 0.5~1 part of calcium powder, 0.8~1.2 part of calcium monohydrogen phosphate, 0.5~1 part of compound amino acid, 0.03~0.05 part of B B-complex
With 0.05~0.1 part of additive B.
According to above-mentioned technical proposal, the screwtree root is serration screwtree root；The rhizoma imperatae is removing fibrous root and film quality leaf
The rhizoma imperatae of sheath；The mulberry leaf are from the mulberry leaf grown on 1 year a diameter of 1.5~2cm of growth branch；The whiteflower cacalia seed is used
0.7~1.2cm of diameter, surface corvinus is glossy, it is seen that the whiteflower cacalia seed of horizontal ring grain or transverse crack.
According to above-mentioned technical proposal, the additive A is feed grade mould inhibitor, by formic acid, propionic acid and inorganic carrier vermiculite
Composition.
According to above-mentioned technical proposal, the additive B is antioxidant, and its component includes dried orange peel, green tea, rosemary, ovum
Phosphatide and citric acid；Preparation method：Dried orange peel, green tea, rosemary are entered into water-filling refluxing extraction respectively, respective extract solution is obtained,
Then the extract solution of three is well mixed, then adds lecithin thereto, citric acid is stirred, dried, is made
's.
The above-mentioned feed for animals with resisiting influenza virus is prepared according to the following steps：
1) cream processed is concentrated：Thinly sliced after rhizoma imperatae and radix scutellariae are cleaned into 2~3 times with warm water, then with screwtree root, sweet wormwood,
Mulberry leaf, whiteflower cacalia seed and Radix Rhapontici seu Radix Echinopsis mixing, which are put into grinding vessel, pulverizes, and the decocting for then adding 10 times of medicinal powder quality boils 40~
Extract solution is obtained after 60 minutes, extract solution is down to after room temperature, add 95% ethanol stir, standing make solution precipitate 20~
30 minutes, the ethanol that supernatant adds 75% continued to staticly settle 20~30 minutes, collects and staticly settles thing concentration for 2 times and be made
Medicinal extract, is put into 4 DEG C of environment and preserves；
2) preparing raw material T：Corn flour, wheat flour, bean cake powder, fish meal, soybean oil and additive A are taken, adds and adjusts after crushing
Device processed carries out modulation curing for the first time, then is passed through ager and carries out second and cure, then cool down, crush raw material T is standby；
3) preparing raw material B：By raw material T and whey powder, white granulated sugar, calcium powder, calcium monohydrogen phosphate, compound amino acid, compound dimension life
Element and additive B, mix, crush raw material Y is standby；
4) mixing curing：Modulator is added after medicinal extract and raw material Y are mixed and carries out third time modulation curing, then is passed through curing
Device carries out the 4th curing, and cooling obtains the feed for animals with resisiting influenza virus；
Wherein, raw material is prepared by following weight ratio：12~30 parts of screwtree root, 6~15 parts of sweet wormwood, 5~15 parts of mulberry leaf, cogongrass
2~6 parts of root, 6~15 parts of whiteflower cacalia seed, 3~8 parts of radix scutellariae, 3~8 parts of Radix Rhapontici seu Radix Echinopsis, 55~60 parts of corn flour, 15~20 parts of wheat flour, beans
15~20 parts of dregs of rice powder, 2~3 parts of fish meal, 2~3 parts of soybean oil, 1~4 part of additive A, 8~10 parts of whey powder, white granulated sugar 1~2
Part, 0.5~1 part of calcium powder, 0.8~1.2 part of calcium monohydrogen phosphate, 0.5~1 part of compound amino acid, 0.03~0.05 part of B B-complex
With 0.05~0.1 part of additive B.
According to above-mentioned technical proposal, the temperature of the first time modulation curing is 90~100 DEG C, and the modulation time is 30~40
Second；The temperature of second of curing is 80~90 DEG C, and the curing time is 1~2 minute；The temperature of the third time modulation curing
For 60~70 DEG C, the modulation time is 30~40 seconds；The temperature of 4th curing is 55~70 DEG C, and the curing time is 1~2 point
Clock.
Compared with prior art, beneficial effects of the present invention：Infected by influenza of the present invention has the curative effect of uniqueness, and convection current is susceptible
Treatment for diseases effect is rapid caused by malicious, has no side effect, while using four curing processes in the preparation process of feed, not only
Raw material can be made to reach preferable amount of cure, reduction nutriment loss improves the transformation efficiency of feed, moreover it is possible to become feed
It is crisp soft, increase palatability, while reducing ANFs and harmful microbe content in raw material, be easy to promote beasts
Growth.
Embodiment
The preferred embodiments of the present invention are illustrated below, it will be appreciated that preferred embodiment described herein is only used
In the description and interpretation present invention, it is not intended to limit the present invention.
Embodiment 1：The present invention provides a kind of feed for animals with resisiting influenza virus, and the feed for animals is by following weight
The raw material of part is made：12 parts of screwtree root, 6 parts of sweet wormwood, 5 parts of mulberry leaf, 2 parts of rhizoma imperatae, 6 parts of whiteflower cacalia seed, 3 parts of radix scutellariae, 3 parts of Radix Rhapontici seu Radix Echinopsis,
55 parts of corn flour, 15 parts of wheat flour, 15 parts of bean cake powder, 2 parts of fish meal, 2 parts of soybean oil, 1 part of additive A, 8 parts of whey powder, white sand
1 part of sugar, 0.5 part of calcium powder, 0.8 part of calcium monohydrogen phosphate, 0.5 part of compound amino acid, 0.03 part of B B-complex and additive B 0.05
Part.
According to above-mentioned technical proposal, the screwtree root is serration screwtree root；The rhizoma imperatae is removing fibrous root and film quality leaf
The rhizoma imperatae of sheath；The mulberry leaf are from the mulberry leaf grown on 1 year a diameter of 1.5~2cm of growth branch；The whiteflower cacalia seed is used
0.7~1.2cm of diameter, surface corvinus is glossy, it is seen that the whiteflower cacalia seed of horizontal ring grain or transverse crack.
According to above-mentioned technical proposal, the additive A is feed grade mould inhibitor, by formic acid, propionic acid and inorganic carrier vermiculite
Composition.
According to above-mentioned technical proposal, the additive B is antioxidant, and its component includes dried orange peel, green tea, rosemary, ovum
Phosphatide and citric acid, are by the way that dried orange peel, green tea, rosemary are entered into water-filling refluxing extraction respectively, respective extract solution is obtained, then
The extract solution of three is well mixed, then adds lecithin thereto, citric acid is stirred, is dried, it is obtained.
The feed for animals that the present embodiment has resisiting influenza virus is prepared according to the following steps：
1) cream processed is concentrated：Thinly sliced after rhizoma imperatae and radix scutellariae are cleaned into 2~3 times with warm water, then with screwtree root, sweet wormwood,
Mulberry leaf, whiteflower cacalia seed and Radix Rhapontici seu Radix Echinopsis mixing, which are put into grinding vessel, pulverizes, and the decocting for then adding 10 times of medicinal powder quality boils 40~
Extract solution is obtained after 60 minutes, extract solution is down to after room temperature, add 95% ethanol stir, standing make solution precipitate 20~
30 minutes, the ethanol that supernatant adds 75% continued to staticly settle 20~30 minutes, collects and staticly settles thing concentration for 2 times and be made
Medicinal extract, is put into 4 DEG C of environment and preserves；
2) preparing raw material T：Corn flour, wheat flour, bean cake powder, fish meal, soybean oil and additive A are taken, adds and adjusts after crushing
Device processed carries out modulation curing for the first time, then is passed through ager and carries out second and cure, then cool down, crush raw material T is standby；
3) preparing raw material B：By raw material T and whey powder, white granulated sugar, calcium powder, calcium monohydrogen phosphate, compound amino acid, compound dimension life
Element and additive B, mix, crush raw material Y is standby；
4) mixing curing：Modulator is added after medicinal extract and raw material Y are mixed and carries out third time modulation curing, then is passed through curing
Device carries out the 4th curing, and cooling obtains the feed for animals with resisiting influenza virus；
Wherein, raw material is prepared by following weight ratio：12 parts of screwtree root, 6 parts of sweet wormwood, 5 parts of mulberry leaf, 2 parts of rhizoma imperatae, whiteflower cacalia seed
6 parts, 3 parts of radix scutellariae, 3 parts of Radix Rhapontici seu Radix Echinopsis, 55 parts of corn flour, 15 parts of wheat flour, 15 parts of bean cake powder, 2 parts of fish meal, 2 parts of soybean oil, additive
A1 parts, 8 parts of whey powder, 1 part of white granulated sugar, 0.5 part of calcium powder, 0.8 part of calcium monohydrogen phosphate, 0.5 part of compound amino acid, B B-complex
0.03 part and 0.05 part of additive B.
The temperature for modulating curing described in the present embodiment for the first time is 95 DEG C, and the modulation time is 35 seconds；Second of curing
Temperature be 85 DEG C, the curing time be 1.5 minutes；The temperature of the third time modulation curing is 65 DEG C, and the modulation time is 35 seconds；
The temperature of 4th curing is 60 DEG C, and the curing time is 1 minute.
Embodiment 2：The present invention provides a kind of feed for animals with resisiting influenza virus, and the feed for animals is by following weight
The raw material of part is made：30 parts of screwtree root, 15 parts of sweet wormwood, 15 parts of mulberry leaf, 6 parts of rhizoma imperatae, 15 parts of whiteflower cacalia seed, 8 parts of radix scutellariae, Radix Rhapontici seu Radix Echinopsis 8
Part, 60 parts of corn flour, 20 parts of wheat flour, 20 parts of bean cake powder, 3 parts of fish meal, 3 parts of soybean oil, 4 parts of additive A, 10 parts of whey powder,
0.1 part of 2 parts of white granulated sugar, 1 part of calcium powder, 1.2 parts of calcium monohydrogen phosphate, 1 part of compound amino acid, 0.05 part of B B-complex and additive B.
According to above-mentioned technical proposal, the screwtree root is serration screwtree root；The rhizoma imperatae is removing fibrous root and film quality leaf
The rhizoma imperatae of sheath；The mulberry leaf are from the mulberry leaf grown on 1 year a diameter of 1.5~2cm of growth branch；The whiteflower cacalia seed is used
0.7~1.2cm of diameter, surface corvinus is glossy, it is seen that the whiteflower cacalia seed of horizontal ring grain or transverse crack.
According to above-mentioned technical proposal, the additive A is feed grade mould inhibitor, by formic acid, propionic acid and inorganic carrier vermiculite
Composition.
According to above-mentioned technical proposal, the additive B is antioxidant, and its component includes dried orange peel, green tea, rosemary, ovum
Phosphatide and citric acid, are by the way that dried orange peel, green tea, rosemary are entered into water-filling refluxing extraction respectively, respective extract solution is obtained, then
The extract solution of three is well mixed, then adds lecithin thereto, citric acid is stirred, is dried, it is obtained.
The feed for animals that the present embodiment has resisiting influenza virus is prepared according to the following steps：
1) cream processed is concentrated：Thinly sliced after rhizoma imperatae and radix scutellariae are cleaned into 2~3 times with warm water, then with screwtree root, sweet wormwood,
Mulberry leaf, whiteflower cacalia seed and Radix Rhapontici seu Radix Echinopsis mixing, which are put into grinding vessel, pulverizes, and the decocting for then adding 10 times of medicinal powder quality boils 40~
Extract solution is obtained after 60 minutes, extract solution is down to after room temperature, add 95% ethanol stir, standing make solution precipitate 20~
30 minutes, the ethanol that supernatant adds 75% continued to staticly settle 20~30 minutes, collects and staticly settles thing concentration for 2 times and be made
Medicinal extract, is put into 4 DEG C of environment and preserves；
2) preparing raw material T：Corn flour, wheat flour, bean cake powder, fish meal, soybean oil and additive A are taken, adds and adjusts after crushing
Device processed carries out modulation curing for the first time, then is passed through ager and carries out second and cure, then cool down, crush raw material T is standby；
3) preparing raw material B：By raw material T and whey powder, white granulated sugar, calcium powder, calcium monohydrogen phosphate, compound amino acid, compound dimension life
Element and additive B, mix, crush raw material Y is standby；
4) mixing curing：Modulator is added after medicinal extract and raw material Y are mixed and carries out third time modulation curing, then is passed through curing
Device carries out the 4th curing, and cooling obtains the feed for animals with resisiting influenza virus；
Wherein, raw material is prepared by following weight ratio：30 parts of screwtree root, 15 parts of sweet wormwood, 15 parts of mulberry leaf, 6 parts of rhizoma imperatae, bitter stone
15 parts of lotus, 8 parts of radix scutellariae, 8 parts of Radix Rhapontici seu Radix Echinopsis, 60 parts of corn flour, 20 parts of wheat flour, 20 parts of bean cake powder, 3 parts of fish meal, 3 parts of soybean oil, add
Plus A4 parts of agent, 10 parts of whey powder, 2 parts of white granulated sugar, 1 part of calcium powder, 1.2 parts of calcium monohydrogen phosphate, 1 part of compound amino acid, B B-complex
0.05 part and 0.1 part of additive B.
The temperature for modulating curing described in the present embodiment for the first time is 90 DEG C, and the modulation time is 30 seconds；Second of curing
Temperature be 80 DEG C, the curing time be 1 minute；The temperature of the third time modulation curing is 60 DEG C, and the modulation time is 30 seconds；Institute
The temperature for stating the 4th curing is 55 DEG C, and the curing time is 1 minute.
Embodiment 3：
Influence of the feed for animals to porkling resisiting influenza virus of the present invention, specific method is：
(1) animal and basal diet：Choose 30 piglets with influenza virus simultaneously.
(2) experiment packet and processing：30 porklings are randomly divided into 3 groups.Ith group is blank control group, feeds basal diet；
The basal diet of IIth group of feeding feed for animals containing embodiment 1, the percentage by weight of feed for animals is 1.0%；IIIth group of feeding
The basal diet of the feed for animals containing embodiment 2, the percentage by weight of feed for animals is 1.0%, and three groups with identical management.
Observation calculates the number of days and body weight of rehabilitation, and result of averaging is as shown in table 1.
Table 1, feeding feed for animals grow the statistics of resisiting influenza virus to porkling
| Group | Number of days needed for taking a turn for the better | Number of days needed for rehabilitation | Compared weightening with blank control group |
| Blank control group | 3 | 7 | 0% |
| IIth group | 2 | 4 | 8.8% |
| IIIth group | 2 | 3 | 9.2% |
As shown in Table 1, porkling influenza rehabilitation compared with blank control group containing embodiment 1 and the Chinese medicine group of embodiment 2 is fed
Used time reduce 42.8% and 57.1%, illustrate feed for animals of the invention can infected by influenza have uniqueness curative effect, convection current
Treatment for diseases effect is rapid caused by Influenza Virus.
Based on above-mentioned, it is an advantage of the current invention that infected by influenza has the curative effect of uniqueness, illness caused by infected by influenza
Therapeutic effect is rapid, has no side effect, while can not only reach raw material using four curing processes in the preparation process of feed
Preferable amount of cure, reduction nutriment loss, improves the transformation efficiency of feed, moreover it is possible to feed is become crisp soft, increases
Plus palatability, while reducing ANFs and harmful microbe content in raw material, it is easy to promote the growth of beasts.
Finally it should be noted that：The preferred embodiment of the present invention is the foregoing is only, is not intended to limit the invention, to the greatest extent
The present invention is described in detail with reference to the foregoing embodiments for pipe, for those skilled in the art, and it still can be with
Technical scheme described in foregoing embodiments is modified, or equivalent substitution is carried out to which part technical characteristic.It is all
Within the spirit and principles in the present invention, any modification, equivalent substitution and improvements made etc., should be included in the guarantor of the present invention
Within the scope of shield.
Claims (6)
1. a kind of feed for animals with resisiting influenza virus, it is characterised in that：The feed for animals by following parts by weight raw material
It is made：12~30 parts of screwtree root, 6~15 parts of sweet wormwood, 5~15 parts of mulberry leaf, 2~6 parts of rhizoma imperatae, 6~15 parts of whiteflower cacalia seed, radix scutellariae 3
~8 parts, 3~8 parts of Radix Rhapontici seu Radix Echinopsis, 55~60 parts of corn flour, 15~20 parts of wheat flour, 15~20 parts of bean cake powder, 2~3 parts of fish meal, soybean
2~3 parts of oil, 1~4 part of additive A, 8~10 parts of whey powder, 1~2 part of white granulated sugar, 0.5~1 part of calcium powder, calcium monohydrogen phosphate 0.8~
0.05~0.1 part of 1.2 parts, 0.5~1 part of compound amino acid, 0.03~0.05 part of B B-complex and additive B.
2. a kind of feed for animals with resisiting influenza virus according to claim 1, it is characterised in that：The screwtree root is
Serration screwtree root；The rhizoma imperatae is removing fibrous root and the rhizoma imperatae of film quality leaf sheath；The mulberry leaf are a diameter of from growing 1 year
The mulberry leaf grown on 1.5~2cm branch；The whiteflower cacalia seed uses 0.7~1.2cm of diameter, and surface corvinus is glossy, can
See the whiteflower cacalia seed of horizontal ring grain or transverse crack.
3. a kind of feed for animals with resisiting influenza virus according to claim 1, it is characterised in that：The additive A
For feed grade mould inhibitor, it is made up of formic acid, propionic acid and inorganic carrier vermiculite.
4. a kind of feed for animals with resisiting influenza virus according to claim 1, it is characterised in that：The additive B
For antioxidant, it is made up of dried orange peel, green tea, rosemary, lecithin and citric acid.
5. the preparation method of the feed for animals with resisiting influenza virus described in claim 1, it is characterised in that：Including following step
Suddenly：
1) cream processed is concentrated：Thinly sliced after rhizoma imperatae and radix scutellariae are cleaned into 2~3 times with warm water, then with screwtree root, sweet wormwood, mulberry leaf,
Whiteflower cacalia seed and Radix Rhapontici seu Radix Echinopsis mixing, which are put into grinding vessel, is pulverized, and the decocting for then adding 10 times of medicinal powder quality is boiled 40~60 minutes
After obtain extract solution, extract solution is down to after room temperature, add 95% ethanol stir, standing make solution precipitate 20~30 points
Clock, the ethanol that supernatant adds 75% continues to staticly settle 20~30 minutes, collects and staticly settles thing concentration for 2 times leaching is made
Cream, is put into 4 DEG C of environment and preserves；
2) preparing raw material T：Modulator is added after taking corn flour, wheat flour, bean cake powder, fish meal, soybean oil and additive A, crushing
Carry out modulation curing for the first time, then be passed through ager and carry out second and cure, then cool down, crush raw material T is standby；
3) preparing raw material B：By raw material T and whey powder, white granulated sugar, calcium powder, calcium monohydrogen phosphate, compound amino acid, B B-complex and
Additive B, mix, crush raw material Y is standby；
4) mixing curing：Add modulator after medicinal extract and raw material Y are mixed and carry out third time modulation curing, then be passed through ager
The 4th curing of row, cooling obtains the feed for animals with resisiting influenza virus；
Wherein, raw material is prepared by following weight ratio：12~30 parts of screwtree root, 6~15 parts of sweet wormwood, 5~15 parts of mulberry leaf, rhizoma imperatae 2
~6 parts, 6~15 parts of whiteflower cacalia seed, 3~8 parts of radix scutellariae, 3~8 parts of Radix Rhapontici seu Radix Echinopsis, 55~60 parts of corn flour, 15~20 parts of wheat flour, dregs of beans
15~20 parts of powder, 2~3 parts of fish meal, 2~3 parts of soybean oil, 1~4 part of additive A, 8~10 parts of whey powder, 1~2 part of white granulated sugar,
0.5~1 part of calcium powder, 0.8~1.2 part of calcium monohydrogen phosphate, 0.5~1 part of compound amino acid, 0.03~0.05 part of B B-complex and add
Plus 0.05~0.1 part of agent B.
6. a kind of preparation method of feed for animals with resisiting influenza virus according to claim 5, it is characterised in that：Institute
The temperature for stating modulation curing for the first time is 90~100 DEG C, and the modulation time is 30~40 seconds；The temperature of second of curing is 80
~90 DEG C, the curing time is 1~2 minute；The temperature of the third time modulation curing is 60~70 DEG C, and the modulation time is 30~40
Second；The temperature of 4th curing is 55~70 DEG C, and the curing time is 1~2 minute.
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Application publication date: 20171024 |
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| RJ01 | Rejection of invention patent application after publication |