CN105194208A - Traditional Chinese medicine composition for treating decubitus and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating decubitus and preparation method of traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention provides traditional Chinese medicine composition for treating decubitus and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises raw materials in parts by weight as follows: 15-30 parts of Chinese starjasmine stems, 10-25 parts of coral ardisia roots, 5-15 parts of roots of pendulous monkshood, 5-15 parts of Japanese thistle herb or roots, 1-5 parts of carbonized petiole of windmill-palm, 5-15 parts of cera Chinensis, 8-15 parts of Indian trum etflower seeds, 1-5 parts of calamine, 5-15 parts of black nightshade herb, 12-18 parts of dioscorea hispida, 5-15 parts of pyrolusite, 8-15 parts of rehmannia roots and 8-15 parts of white paeony roots. The traditional Chinese medicine composition is targeted at the pathogenesis of decubitus, can be used for treating decubitus by activating blood circulation, removing stasis, nourishing blood, moistening the skin, drawing out toxin, expelling pus, astringing to stop bleeding, engendering flesh to heal ulcer, removing swelling and relieving pain, and has the advantages that the anti-infection performance is high, a wound can be healed quickly and decubitus is not prone to relapse after being cured.
Description
[technical field]
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of decubital ulcer and preparation method thereof.
[background technology]
Decubital ulcer (decubitus) has another name called pressure ulcer (pressuresores), is that the long-term pressurized of body part makes blood circulation be obstructed, and the skin caused and subcutaneous tissue ischemia and vesicle, ulcer or gangrene occur.Clinically, decubital ulcer I degree (erythema phase), decubital ulcer II degree (vesicle phase) and decubital ulcer III degree (ulcerative stage) three phase is divided into according to the forming process of decubital ulcer and the order of severity.Show as in the erythema phase: the compression zone position of whole body shows as local stasis of blood, and skin presents erythema; The vesicle phase shows as: the blister differed in size appears in pressurized position, and skin rubefaction is congested, does not disappear with during finger pressure; Ulcerative stage shows as: ulcer is no more than skin holostrome, and because ulcer basilar part lacks blood supply, in pale asphyxia, granulation edema, flowing water is more than, and severe patient involves fascia and muscle, and traumatic infection is serious.Decubital ulcer is once be formed, and state of an illness Progressive symmetric erythrokeratodermia develops, and controls for a long time difficult more then bring misery to patient, affect the treatment of disease, heavy then secondary infection, concurrent septicemia and threat to life.The common method of current treatment decubital ulcer for local change dressings, the measure such as infra-red light irradiation, quiet Chinese medicinal ointment such as antibiotic, JINGWANHONG are smeared, often take effect slow, DeGrain, the unclean easy incrustation of rear wound surface smeared by ointment, incrustation not only limits granulation and epithelial growth, and easily infects under crust, and impaired wound healing closes, the side effect of part Western medicine prolonged application is large, and the health for patient causes serious injury.
[summary of the invention]
Goal of the invention of the present invention is: for above-mentioned Problems existing, a kind of Chinese medicine composition for the treatment of decubital ulcer and preparation method thereof is provided, the pathogenesis that this Chinese medicine composition occurs for decubital ulcer, pass through blood circulation promoting and blood stasis dispelling, blood-nourishing skin-moisturizing, evacuation of pus of drawing out pus by applying a plaster to the affected part, astringing to arrest bleeding, promoting tissue regeneration and ulcer healing, reducing swelling and alleviating pain treats decubital ulcer.Have and have that infection is strong, wound healing soon, more after the advantage that not easily recurs.
To achieve these goals, the technical solution used in the present invention is as follows:
Treat a Chinese medicine composition for decubital ulcer, be made up of the raw material of following weight portion: trachelospermum jasminoide 15-30 part, Radix Ardisiae Crenatae 10-25 part, Radix aconiti szechenyiani 5-15 part, Radix Cirsii Japonici 5-15 part, charred Petiolus Trachycarpi 1-5 part, Cera Chinensis 5-15 part, Semen Oroxyli 8-15 part, Calamina 1-5 part, Herba Solani Nigri 5-15 part, sweet potato gelsemium 12-18 part, pyrolusitum 5-15 part, Radix Rehmanniae 8-15 part, Radix Paeoniae Alba 8-15 part.
Further, this Chinese medicine composition is made up of the raw material of following weight portion: trachelospermum jasminoide 18-25 part, Radix Ardisiae Crenatae 12-20 part, Radix aconiti szechenyiani 8-12 part, Radix Cirsii Japonici 8-12 part, charred Petiolus Trachycarpi 2-4 part, Cera Chinensis 7-12 part, Semen Oroxyli 9-12 part, Calamina 2-4 part, Herba Solani Nigri 8-12 part, sweet potato gelsemium 14-16 part, pyrolusitum 8-12 part, Radix Rehmanniae 10-13 part, Radix Paeoniae Alba 10-12 part.
Further, this Chinese medicine composition is made up of the raw material of following weight portion: trachelospermum jasminoide 24 parts, Radix Ardisiae Crenatae 16 parts, Radix aconiti szechenyiani 10 parts, Radix Cirsii Japonici 10 parts, charred Petiolus Trachycarpi 3 parts, Cera Chinensis 10 parts, Semen Oroxyli 10 parts, Calamina 3 parts, Herba Solani Nigri 10 parts, sweet potato gelsemium 15 parts, pyrolusitum 10 parts, Radix Rehmanniae 12 parts, the Radix Paeoniae Alba 11 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment decubital ulcer, comprise the following steps: take raw material of Chinese medicine according to aforesaid weight portion, charred Petiolus Trachycarpi, Calamina are pulverized, remaining starting material with water is soaked 1-2h then decoct 2-3 time, add institute soak medicine gross weight 5-8 water doubly at every turn, decoct 1-2 hour, merge decoction liquor, filter; When filtrate is condensed into 25 DEG C, relative density is the extractum of 1.20-1.32, charred Petiolus Trachycarpi after cold drying after grinding, be ground into the traditional Chinese medicine fine powder of 300 mesh sieves together with Calamina, and eventually passed normal process steps and add pharmaceutically acceptable excipients and make clinical acceptable dosage form.Described dosage form is preferably ointment.
Further, the prescription of described ointment is: traditional Chinese medicine fine powder 100-120g, spermol 70-80g, vaseline 80-90g, glycerol 35-45ml.
Further, the preparation method of described ointment comprises following steps: take the spermol of recipe quantity, vaseline, glycerol is heated to 70 DEG C and stirs evenly, filter and make oil phase, traditional Chinese medicine fine powder slowly added in oil phase, stir both ointment.
Effect of each raw material of Chinese medicine used in the present invention is as follows:
Trachelospermum jasminoide, root, stem, leaf, fruit hyoscine, have the usefulness of dispelling, collateral-activating, sharp joint, hemostasis, alleviating pain and detumescence, heat-clearing and toxic substances removing.Be applicable to arthralgia, myalgia, the diseases such as soreness of waist and knee joint; Also can dissipate all skin ulcers, removes laryngopharynx swelling and pain.
Radix Ardisiae Crenatae, bitter in the mouth is cool, nontoxic.There is resolving heat and reducing pathogenic fire, effect of subduing swelling and detoxicating, blood circulation and promoting silt, expelling phlegm for arresting cough, anthelmintic and parasite killing.Main laryngopharynx swelling and pain; Beriberoid pyretic arthralgia; Jaundice; Dysentery; Traumatic injury; Erysipelas; Mastitis; Orchitis.
Radix aconiti szechenyiani is bitter; Pungent; Temperature; Very toxic.Lung; Heart channel.There is blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, effect of reducing swelling and alleviating pain.Cure mainly traumatic injury, fracture pain caused by ecchymoma, lumbago due to pathogenic wind-dampness, carbuncle malignant boil, innominate toxic swelling, the routed person of scrofula, venom, chilblain.
Caulis et Folium Pavettae Hongkongensis, toil; Cold, the heart; Spleen channel.There is heat-clearing and toxic substances removing, effect of blood circulation promoting and blood stasis dispelling.Cure mainly summer-heat acute filthy disease, traumatic injury, pathogenic wind-toxic sore scabies.
Radix Cirsii Japonici, cool in nature, sweet in the mouth is bitter, nontoxic.GUIXIN, Liver Channel.There is heat-clearing and toxic substances removing, antiinflammatory, stop blooding and recover the effect of liver function, promotion liver cell regeneration, curing mainly haematemesis, epistaxis, hematuria, stranguria with blood, metrorrhagia, leukorrhagia, hemorrhoidal hamorrhage, acute appendicitis, carbuncle and ulcer toxic swelling, furuncle.Be applicable to acute calenture struvite hemorrhage, yellow cellulitis, hepatitis, pyretic stranguria, hematuria etc.Radix Cirsii Japonici also has antibacterial action, can suppress the growth of human-like poisonous tulase in vitro, have inhibitory action during ethanol preserved material 1:3000 to mycobacterium hominis when its root decoct or herb distillate 1:4000 concentration.
Charred Petiolus Trachycarpi, has anastaltic effect, for haematemesis, epistaxis, have blood in stool, the card such as metrorrhagia, cure mainly spitting of blood, haematemesis, epistaxis, have blood in stool, metrorrhagia, the card such as menorrhagia and without the stagnant person of the stasis of blood.
Semen Oroxyli, mildly bitter flavor, sweet, cold nature.Return lung, liver, stomach warp.There is sore-throat relieving lung moistening, dispersing the stagnated liver-QI for regulating the stomach, effect of expelling pus and promoting granulation.Cure mainly pharyngalgia sore throat; Hoarseness; Cough; Stomachache due to hyperactive liver-QI attacking the stomach; Skin infection is burst for a long time and is not held back; Acute eczema.
Calamina, is water-fast natural magnesium zinc, is widely used in department of dermatologry, as anticorrosion, convergence, the protective agent treatment scytitis or surface injury of moderate.External can suppress local aureus growth, can partially absorb wound extract, have convergence, protective effect; Still can suppress the staphylococcic growth in local.
Herba Solani Nigri, cold in nature, bitter in the mouth, micro-sweet; Slightly poisonous.Heat-clearing and toxic substances removing, diuresis, effect of antiinflammatory.For sore and toxic, skin eczema, dysuria, chronic senile tracheitis, leukorrhagia, prostatitis, dysentery.
Sweet potato gelsemium, has removing toxic substances, detumescence, pain relieving, effect of blood stasis removing hemostasis.Cure mainly skin infection, scrofula, innominate toxic swelling, treating swelling and pain by traumatic injury, traumatic hemorrhage.
Pyrolusitum, salty in the mouth, sweet, property is put down, slightly poisonous.Return liver, kidney channel.There is blood stasis removing hemostasis, reducing swelling and alleviating pain, effect of promoting tissue regeneration and ulcer healing.Cure mainly traumatic injury, incised wound is hemorrhage, carbuncle skin infection, burn due to hot liquid or fire.
Radix Rehmanniae Preparata, sweet in the mouth, tepor.GUIXIN, liver, kidney channel.Have YIN nourishing of enriching blood, beneficial essence fills out marrow, heart tonifying, diuresis, blood sugar lowering, raises peripheral leukocytes, strengthens the effects such as immunologic function.For blood deficiency and yellow complexion, dizzy, palpitation and insomnia, menoxenia, metrorrhagia etc.
The Radix Paeoniae Alba, cool in nature, bitter in the mouth acid, is slightly cold, and has the effects such as invigorating qi and benefiting blood, whitening and moistening skin, suppressing the hyperactive liver pain relieving, yin fluid astringing receipts antiperspirant, is applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction suddenly, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.
Using method after the Chinese medicine composition that the present invention treats decubital ulcer makes ointment is: use normal saline to be cleaned by bedsore wound, band bed sore ointment is smeared in bedsore wound, ointment thickness is about 1-2mm, coating scope exceedes wound surface scope 1-2cm, then nontoxic preservative film is covered, bandage again, change dressings every day 2 times.
If make powder, after can being in harmonious proportion with appropriate Oleum Sesami, smear use as stated above.
In sum, owing to have employed technique scheme, the invention has the beneficial effects as follows:
The present invention treats the Chinese medicine composition of decubital ulcer, due to the large damage of QI and blood for decubital ulcer, run not normal, can not nutrition skin and causing a disease, have employed blood circulation promoting and blood stasis dispelling, blood-nourishing skin-moisturizing, evacuation of pus of drawing out pus by applying a plaster to the affected part, astringing to arrest bleeding, promoting tissue regeneration and ulcer healing, the Chinese herbal medicine of reducing swelling and alleviating pain adds excipient and obtains, the scientific formula reasonable compatibility of Chinese herbal medicine, with trachelospermum jasminoide, Radix Ardisiae Crenatae for monarch drug, there is blood circulation promoting and blood stasis dispelling, promote effect of local blood circulation, the effect of enrich blood with Radix Rehmanniae Preparata, the Radix Paeoniae Alba training gas, nutrition skin, reinforcement blood circulation promoting and blood stasis dispelling, blood-nourishing skin-moisturizing; Assistant is with anastaltic charred Petiolus Trachycarpi, Radix Cirsii Japonici; Assistant is with the Cera Chinensis of promoting tissue regeneration and ulcer healing, Semen Oroxyli, Calamina, the Herba Solani Nigri of reducing swelling and alleviating pain, evacuation of pus of drawing out pus by applying a plaster to the affected part, sweet potato gelsemium and pyrolusitum, kinds of traditional Chinese medicines complements each other, play blood circulation promoting and blood stasis dispelling altogether, blood-nourishing skin-moisturizing, evacuation of pus of drawing out pus by applying a plaster to the affected part, astringing to arrest bleeding, promoting tissue regeneration and ulcer healing, the pharmacological function effect of reducing swelling and alleviating pain, and then fundamentally can cure decubital ulcer accurately and rapidly.This Chinese medicine composition is a kind of medicine of debating disease treatment, and pointed height, therapeutic effect are good, effective percentage is high, advantage to human non-toxic's side effect.
[detailed description of the invention]
The invention provides a kind of Chinese medicine composition for the treatment of decubital ulcer, be made up of the raw material of following weight portion: trachelospermum jasminoide 15-30 part, Radix Ardisiae Crenatae 10-25 part, Radix aconiti szechenyiani 5-15 part, Radix Cirsii Japonici 5-15 part, charred Petiolus Trachycarpi 1-5 part, Cera Chinensis 5-15 part, Semen Oroxyli 8-15 part, Calamina 1-5 part, Herba Solani Nigri 5-15 part, sweet potato gelsemium 12-18 part, pyrolusitum 5-15 part, Radix Rehmanniae 8-15 part, Radix Paeoniae Alba 8-15 part.The pathogenesis that this Chinese medicine composition occurs for decubital ulcer, by blood circulation promoting and blood stasis dispelling, blood-nourishing skin-moisturizing, evacuation of pus of drawing out pus by applying a plaster to the affected part, astringing to arrest bleeding, promoting tissue regeneration and ulcer healing, reducing swelling and alleviating pain treats decubital ulcer.Have and have that infection is strong, wound healing soon, more after the advantage that not easily recurs.Below by way of specific embodiment, the invention will be further described.
Embodiment 1
Take following raw material by weight ratio: trachelospermum jasminoide 15 parts, Radix Ardisiae Crenatae 10 parts, Radix aconiti szechenyiani 5 parts, Radix Cirsii Japonici 5 parts, charred Petiolus Trachycarpi 3 parts, Cera Chinensis 5 parts, Semen Oroxyli 8 parts, Calamina 8 parts, Herba Solani Nigri 5 parts, sweet potato gelsemium 12 parts, pyrolusitum 5 parts, Radix Rehmanniae 8 parts, the Radix Paeoniae Alba 8 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment decubital ulcer, prepares: take raw material of Chinese medicine according to aforesaid weight portion, charred Petiolus Trachycarpi, Calamina are pulverized according to the following steps; Remaining starting material with water is soaked 1h and then decocts 2 times, add the water of institute's soak medicine gross weight 5 times at every turn, decoct 1 hour, merge decoction liquor, filter; When filtrate is condensed into 25 DEG C, relative density is the extractum of 1.20, is ground into the traditional Chinese medicine fine powder of 300 mesh sieves after cold drying together with the charred Petiolus Trachycarpi after grinding, Calamina, eventually passes normal process steps and adds pharmaceutically acceptable excipients and make ointment.
Ointment preparation method is, takes traditional Chinese medicine fine powder 100g, spermol 70g, vaseline 80g, glycerol 35ml; Spermol, vaseline, glycerol are heated to 70 DEG C and stir evenly, filters and make oil phase, traditional Chinese medicine fine powder is slowly added in oil phase, stir and both obtain ointment.
Embodiment 2
Take following raw material by weight ratio: trachelospermum jasminoide 18 parts, Radix Ardisiae Crenatae 12 parts, Radix aconiti szechenyiani 8 parts, Radix Cirsii Japonici 8 parts, charred Petiolus Trachycarpi 2 parts, Cera Chinensis 7 parts, Semen Oroxyli 9 parts, Calamina 2 parts, Herba Solani Nigri 8 parts, sweet potato gelsemium 14 parts, pyrolusitum 8 parts, Radix Rehmanniae 10 parts, the Radix Paeoniae Alba 10 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment decubital ulcer, prepares: take raw material of Chinese medicine according to aforesaid weight portion, charred Petiolus Trachycarpi, Calamina are pulverized according to the following steps; Remaining starting material with water is soaked 2h and then decocts 3 times, add the water of institute's soak medicine gross weight 8 times at every turn, decoct 2 hours, merge decoction liquor, filter; When filtrate is condensed into 25 DEG C, relative density is the extractum of 1.32, is ground into the traditional Chinese medicine fine powder of 300 mesh sieves after cold drying together with the charred Petiolus Trachycarpi after grinding, Calamina, eventually passes normal process steps and adds pharmaceutically acceptable excipients and make ointment.
Ointment preparation method is, takes traditional Chinese medicine fine powder 120g, spermol 80g, vaseline 90g, glycerol 45ml; Spermol, vaseline, glycerol are heated to 70 DEG C and stir evenly, filters and make oil phase, traditional Chinese medicine fine powder is slowly added in oil phase, stir and both obtain ointment.
Embodiment 3
Take following raw material by weight ratio: trachelospermum jasminoide 24 parts, Radix Ardisiae Crenatae 16 parts, Radix aconiti szechenyiani 10 parts, Radix Cirsii Japonici 10 parts, charred Petiolus Trachycarpi 3 parts, Cera Chinensis 10 parts, Semen Oroxyli 10 parts, Calamina 3 parts, Herba Solani Nigri 10 parts, sweet potato gelsemium 15 parts, pyrolusitum 10 parts, Radix Rehmanniae 12 parts, the Radix Paeoniae Alba 11 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment decubital ulcer, prepares: take raw material of Chinese medicine according to aforesaid weight portion, charred Petiolus Trachycarpi, Calamina are pulverized according to the following steps; Remaining starting material with water is soaked 1.5h and then decocts 2 times, add the water of institute's soak medicine gross weight 6 times at every turn, decoct 1.5 hours, merge decoction liquor, filter; When filtrate is condensed into 25 DEG C, relative density is the extractum of 1.28, is ground into the traditional Chinese medicine fine powder of 300 mesh sieves after cold drying together with the charred Petiolus Trachycarpi after grinding, Calamina, eventually passes normal process steps and adds pharmaceutically acceptable excipients and make ointment.
Ointment preparation method is, takes traditional Chinese medicine fine powder 110g, spermol 75g, vaseline 85g, glycerol 40ml; Spermol, vaseline, glycerol are heated to 70 DEG C and stir evenly, filters and make oil phase, traditional Chinese medicine fine powder is slowly added in oil phase, stir and both obtain ointment.
Embodiment 4
Take following raw material by weight ratio: trachelospermum jasminoide 25 parts, Radix Ardisiae Crenatae 20 parts, Radix aconiti szechenyiani 12 parts, Radix Cirsii Japonici 12 parts, charred Petiolus Trachycarpi 4 parts, Cera Chinensis 12 parts, Semen Oroxyli 12 parts, Calamina 4 parts, Herba Solani Nigri 12 parts, sweet potato gelsemium 16 parts, pyrolusitum 12 parts, Radix Rehmanniae 13 parts, the Radix Paeoniae Alba 12 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment decubital ulcer, prepares: take raw material of Chinese medicine according to aforesaid weight portion, charred Petiolus Trachycarpi, Calamina are pulverized according to the following steps; Remaining starting material with water is soaked 2h and then decocts 2 times, add the water of institute's soak medicine gross weight 5 times at every turn, decoct 2 hours, merge decoction liquor, filter; When filtrate is condensed into 25 DEG C, relative density is the extractum of 1.30, is ground into the traditional Chinese medicine fine powder of 300 mesh sieves after cold drying together with the charred Petiolus Trachycarpi after grinding, Calamina, eventually passes normal process steps and adds pharmaceutically acceptable excipients and make ointment.
Ointment preparation method is, takes traditional Chinese medicine fine powder 105g, spermol 72g, vaseline 83g, glycerol 39ml; Spermol, vaseline, glycerol are heated to 70 DEG C and stir evenly, filters and make oil phase, traditional Chinese medicine fine powder is slowly added in oil phase, stir and both obtain ointment.
Embodiment 5
Take following raw material by weight ratio: trachelospermum jasminoide 30 parts, Radix Ardisiae Crenatae 25 parts, Radix aconiti szechenyiani 15 parts, Radix Cirsii Japonici 15 parts, charred Petiolus Trachycarpi 8 parts, Cera Chinensis 15 parts, Semen Oroxyli 15 parts, Calamina 15 parts, Herba Solani Nigri 15 parts, sweet potato gelsemium 18 parts, pyrolusitum 15 parts, Radix Rehmanniae 15 parts, the Radix Paeoniae Alba 15 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment decubital ulcer, prepares: take raw material of Chinese medicine according to aforesaid weight portion, charred Petiolus Trachycarpi, Calamina are pulverized according to the following steps; Remaining starting material with water is soaked 1h and then decocts 3 times, add the water of institute's soak medicine gross weight 6 times at every turn, decoct 1.5 hours, merge decoction liquor, filter; When filtrate is condensed into 25 DEG C, relative density is the extractum of 1.25, is ground into the traditional Chinese medicine fine powder of 300 mesh sieves after cold drying together with the charred Petiolus Trachycarpi after grinding, Calamina, eventually passes normal process steps and adds pharmaceutically acceptable excipients and make ointment.
Ointment preparation method is, takes traditional Chinese medicine fine powder 115g, spermol 78g, vaseline 85g, glycerol 42ml; Spermol, vaseline, glycerol are heated to 70 DEG C and stir evenly, filters and make oil phase, traditional Chinese medicine fine powder is slowly added in oil phase, stir and both obtain ointment.
Clinical effectiveness is verified
1, case selection: clinical patients is totally 88 examples, wherein male 43 example, women 45 example, 65 years old mean age.Through comprehensive health check-up, all without complication such as septicemia.According to patient's decubital ulcer by stages and the order of severity mark, be divided into two groups, treatment group and matched group, the decubital ulcer overall score result no difference of science of statistics of selected two groups.
2, Therapeutic Method:
Treatment group: use normal saline to be cleaned by bedsore wound, smeared by band bed sore ointment in bedsore wound, ointment thickness is about 1-2mm, coating scope exceedes wound surface scope 1-2cm, then covers nontoxic preservative film, then bandages, changing dressings every day 2 times, seven days is a course for the treatment of, observes 3 courses for the treatment of.
Matched group: use normal saline to be cleaned by bedsore wound, be coated with Gentian Violet liquid medicine in affected part, area, slightly larger than affected part, is changed dressings 2 times every day, seven days is a course for the treatment of, observes 3 courses for the treatment of.
3, efficacy assessment standard:
Efficacy assessment standard with reference to decubital ulcer in People's Republic of China's traditional Chinese medicine industry standard " Chinese medical disease Standardization of diagnosis and curative effect ":
Recovery from illness: ulcer surface heals completely, clinical symptom disappearance, follows up a case by regular visits to 2 months without recurrence.
Effective: ulcer area reduces and reaches more than 70%, and clinical symptoms disappears substantially.
Take a turn for the better: ulcer area reduces more than 30%, clinical symptoms is improved.
Invalid: to treat 3 courses for the treatment of, ulcer area reduces less than 30% or unchanged, or expands, and clinical symptoms is without improvement.
4, therapeutic outcome: be shown in Table 1.
Table 1 therapeutic outcome
| Group | Number | Recovery from illness | Effective | Take a turn for the better | Invalid | Total effective rate |
| Treatment group | 44 | 24(54.6％) | 10(22.7％) | 8(18.2％) | 2(4.5％) | 95.5％ |
| Matched group | 44 | 15(34.1％) | 10(22.7％) | 6(13.6％) | 13(29.6％) | 70.4％ |
Two groups of comparitive study treatment group cure rates, total effective rates, be obviously better than matched group, have comparability.P<0.05。
Model case: Xu certain, female, 73 years old, suffer stroke 1 year, right side upper and lower extremities mobility is lost, because long-term bed, compressing, right hips portion form diameter and be about the dark about 2cm decubital ulcer of 6cm, smear affected part with this medicine and be about 1-2 millimeters thick, twice daily, after 3 days, pain alleviates, in kind and consumption use 15 days after the healing of the open sore part large portion, in kind and consumption adhere to smearing 30 days after be almost recovered.
Claims (7)
1. treat a Chinese medicine composition for decubital ulcer, it is characterized in that being made up of the raw material of following weight portion: trachelospermum jasminoide 15-30 part, Radix Ardisiae Crenatae 10-25 part, Radix aconiti szechenyiani 5-15 part, Radix Cirsii Japonici 5-15 part, charred Petiolus Trachycarpi 1-5 part, Cera Chinensis 5-15 part, Semen Oroxyli 8-15 part, Calamina 1-5 part, Herba Solani Nigri 5-15 part, sweet potato gelsemium 12-18 part, pyrolusitum 5-15 part, Radix Rehmanniae 8-15 part, Radix Paeoniae Alba 8-15 part.
2. a kind of Chinese medicine composition for the treatment of decubital ulcer according to claim 1, it is characterized in that being made up of the raw material of following weight portion: trachelospermum jasminoide 18-25 part, Radix Ardisiae Crenatae 12-20 part, Radix aconiti szechenyiani 8-12 part, Radix Cirsii Japonici 8-12 part, charred Petiolus Trachycarpi 2-4 part, Cera Chinensis 7-12 part, Semen Oroxyli 9-12 part, Calamina 2-4 part, Herba Solani Nigri 8-12 part, sweet potato gelsemium 14-16 part, pyrolusitum 8-12 part, Radix Rehmanniae 10-13 part, Radix Paeoniae Alba 10-12 part.
3. treat a Chinese medicine composition for decubital ulcer, it is characterized in that being made up of the raw material of following weight portion: trachelospermum jasminoide 24 parts, Radix Ardisiae Crenatae 16 parts, Radix aconiti szechenyiani 10 parts, Radix Cirsii Japonici 10 parts, charred Petiolus Trachycarpi 6 parts, Cera Chinensis 10 parts, Semen Oroxyli 10 parts, Calamina 3 parts, Herba Solani Nigri 10 parts, sweet potato gelsemium 15 parts, pyrolusitum 10 parts, Radix Rehmanniae 12 parts, the Radix Paeoniae Alba 11 parts.
4. a kind of preparation method for the treatment of the Chinese medicine composition of decubital ulcer according to any one of claim 1-3, it is characterized in that comprising the following steps: take raw material of Chinese medicine according to aforesaid weight portion, charred Petiolus Trachycarpi, Calamina are pulverized, remaining starting material with water is soaked 1-2h then decoct 2-3 time, add institute soak medicine gross weight 5-8 water doubly at every turn, decoct 1-2 hour, merge decoction liquor, filter; When filtrate is condensed into 25 DEG C, relative density is the extractum of 1.20-1.32, charred Petiolus Trachycarpi after cold drying after grinding, be ground into the traditional Chinese medicine fine powder of 300 mesh sieves together with Calamina, and eventually passed normal process steps and add pharmaceutically acceptable excipients and make clinical acceptable dosage form.
5. a kind of preparation method for the treatment of the Chinese medicine composition of decubital ulcer according to claim 4, is characterized in that: described dosage form is ointment.
6. a kind of preparation method for the treatment of the Chinese medicine composition of decubital ulcer according to claim 5, is characterized in that the prescription of described ointment is: traditional Chinese medicine fine powder 100-120g, spermol 70-80g, vaseline 80-90g, glycerol 35-45ml.
7. a kind of preparation method for the treatment of the Chinese medicine composition of decubital ulcer according to claim 6, it is characterized in that the preparation method of described ointment comprises following steps: take the spermol of recipe quantity, vaseline, glycerol is heated to 70 DEG C and stirs evenly, oil phase is made in filtration, traditional Chinese medicine fine powder is slowly added in oil phase, stirs and both obtain ointment.
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| CN201510726968.7A Pending CN105194208A (en) | 2015-10-29 | 2015-10-29 | Traditional Chinese medicine composition for treating decubitus and preparation method of traditional Chinese medicine composition |
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| CN101194929A (en) * | 2007-12-11 | 2008-06-11 | 徐东健 | Powder medicament for treating decubitus |
| CN101543565A (en) * | 2009-05-19 | 2009-09-30 | 卜继武 | Chinese medicine external-use preparation medicament for treating surgery wound infection and method for producing the same |
| CN101708222A (en) * | 2009-11-23 | 2010-05-19 | 马红银 | Chinese medicinal unguent for treating bedsore and preparation method thereof |
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