CN105169117A - Medicine for treating stroke and preparation method - Google Patents

Medicine for treating stroke and preparation method Download PDF

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CN105169117A
CN105169117A CN201510544622.5A CN201510544622A CN105169117A CN 105169117 A CN105169117 A CN 105169117A CN 201510544622 A CN201510544622 A CN 201510544622A CN 105169117 A CN105169117 A CN 105169117A
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water
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antapoplectic
powder
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李玉欣
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Abstract

The invention discloses medicine for treating stroke and a preparation method. The medicine is prepared by, by weight, 10-16 parts of jujube, 8-15 parts of ginseng flower, 6-14 parts of rhaphidophora peepla, 9-16 parts of malt, 7-12 parts of pygmy arrowhead herb, 8-13 parts of acajounut, 10-13 parts of gentiana macrophylla, 8-14 parts of isodon amethystoides, 9-13 parts of pittosporm root, 7-14 parts of Hongkong pavetta leaf, 6-13 parts of laxleaf beautifulflower millettia root, 9-14 parts of star-flower lysimachia, 7-13 parts of terminalia bellirica and 10-14 parts of caulis bambusae in taeniam. The medicine is evident in curative effect, high in cure rate, safe, free of toxic and side effects, low in treatment cost, capable of treating both symptoms and root causes and less prone to relapse.

Description

The antapoplectic medicament of a kind of doctor and method for making
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to the antapoplectic medicament of a kind of doctor and method for making.
Background technology
Apoplexy is the general designation of Chinese medicine to acute cerebrovascular disease.It is suddenly fainted, syncope, the distortion of commissure that occurs together, dysphonia and occur that hemiplegia is a class disease of cardinal symptom.The primary disease cause of disease is more, and from clinical, with endogenous cause of ill, occasioner is in the majority.The generation of apoplexy, is summed up not outer empty (deficiency of YIN, the deficiency of vital energy), fire (liver-fire, heart-fire), wind (liver-wind, exogenous wind), expectorant (wind-phlegm, damp-phlegm), gas (QI rising in reverse order), blood (blood stasis) six end.(1) feelings will is disgruntled.Overaction of the five emotions, heart-fire cruelly very, can priming endogenous wind and send out apoplexy.Clinical is many with rage impairing the liver, and because of rage then extreme hyperactivity of the liver-yang in no time, gas fire is all floating, and forcing blood gushes, and its time must be sent out.Probably sad as troubled thoughts, the nervous inducement being primary disease.(2) eating and drinking without temperance.Surfeit delicious food pure wine, dysfunction of the spleen in transportation, accumulatively wet raise phlegm, stagnation of phlegm converting into heat, priming liver-wind, folder expectorant is disturbed, can cause a disease and send out, especially bring out the strongest with excessive drinking.(3) overwork." Plain Questions vital QI of the body connecting with natural QI opinion " is said: " yang-energy person, bothers, and opens ", namely refers to personal yang-energy, if disturbance too, then excitedly not to hold back.Primary disease also can because managing excessively, and body and the spirit is lost and supported, so that cloudy blood secretly consumes, and empty positive wind-transformation disturbance is for suffering from.Moreover indulge in sensual pleasures wound essence, be also water lose under, hyperactivity of fire in upper, morbidity because of.(4) climate change.Primary disease all can occur throughout the year, but changes relevant with seasonal climate.Entering the winter turns cold suddenly, and cold-evil invades, and can affect blood vessels and follow row.Say as " Plain Questions regulating menstruation opinion " " cold solely to stay, then blood clotting position, solidifying then arteries and veins is obstructed ... ".Secondly suddenly turn early spring when warming up, on the occasion of the main order of chilly wind wood of fainting, planted agent is in liver, and wind sun is dark dynamic, and primary disease also can be caused to occur.(5) the blood stasis of blood is stagnant.The formation of blood stasis many because of stagnation of QI hematogenous blockage or deficiency of vital energy fortune blood unable, or to accumulate in upper because of rage blood, or stagnate because feeling cold spasm, or to hinder liquid hematozemia stagnant etc. because of the moon of heat, the pathogenesis of primary disease accumulate mainly with rage blood or blood stasis due to qi deficiency the most common.
Develop and publish the method for syndrome differentiation about apoplexy apoplex involving the channels and collaterals in " new Chinese medicine guideline of clinical investigations " according to Ministry of Public Health in 1993, be divided into extreme hyperactivity of the liver-yang, wind-fire upper harassing syndrome; Wind-phlegm blood stasis, numbness resistance venation card; Phlegm-heat accumulation, syndrome of wind-phlegm invading upward; Syndrome of blood stasis due to qi deficiency; Five types such as stirring of wind due to deficiency of YIN card.The dialectical syndrome treated in each pattern of syndrome is shown in the clinical manifestation of five types.Determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs: (1) extreme hyperactivity of the liver-yang, wind fire pathogen.Syndrome: hemiplegia, crooked mouth and tongue, stiff tongue and retardation in speech or in silence, hemianesthesia, dizziness and headache, flushing conjunctival congestion, bitter taste in the mouth and dry throat, susceptible to lose temper due to restlessness, dark coloured urine dry stool, red tongue or red deep red, tongue fur BOHUANG, wiry forceful pulse.The rule for the treatment of: suppressing the hyperactive liver to arrest the wind syndrome, nourishing YIN for suppressing the hyperactive YANG.Main formula: Zhengan Xifeng Tang is added and subtracted.Side's medicine: Radix Achyranthis Bidentatae, Haematitum, Os Draconis, Concha Ostreae, the Radix Paeoniae Alba, Radix Scrophulariae, Carapax et Plastrum Testudinis, Radix Asparagi, Herba Artemisiae Scopariae, Fructus Toosendan, Fructus Hordei Germinatus, Radix Glycyrrhizae.As excessive rising of liver-YANG notably adds Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis to strengthen the power of suppressing the hyperactive liver to relieve the wind syndrome; Vexed Fructus Gardeniae, the Radix Scutellariae of notably adding is with clearing heat and relieving fidgetness; Comparatively severe one of having a headache adds Cornu Saigae Tataricae, Concha Haliotidis, Spica Prunellae with the sun that relieves dizziness, high fever, infantile convulsions, epilepsy, etc. clearly; Expectorant heat comparatively severe one, adds Arisaema Cum Bile, Succus Bambusae, Bulbus Fritillariae Cirrhosae with clearing and dissipating phlegm-heat.(2) wind-phlegm blood stasis, numbness resistance venation.Syndrome: hemiplegia, crooked mouth and tongue, stiff tongue speech is not smoothgoing or in silence, hemianesthesia, has a dizzy spell, dimly pale tongue, thin white fur of tongue or greasy in vain, stringy and rolling pulse.The rule for the treatment of: dispel the wind, nourish blood, invigorate blood circulation, eleminating phlegm and freeing channels.Main formula: daqinjiao decoction is added and subtracted.Side's medicine: Radix Gentianae Macrophyllae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Saposhnikoviae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Scutellariae, Gypsum Fibrosum, the Radix Rehmanniae.As person worn with age, add the Radix Astragali with QI invigorating righting.As vomiting abundant expectoration, greasy fur rolling pulse notably, go Radix Rehmanniae, add the expectorant that dispel the wind such as the Rhizoma Pinelliae, Rhizoma Arisaematis, Rhizoma Typhonii, Scorpio, the meridian dredging.Can de-stone cream, Radix Scutellariae without interior-heat person.(3) phlegm-heat accumulation, wind-phlegm are disturbed.Syndrome: hemiplegia, crooked mouth and tongue, stiff tongue speech is not smoothgoing or in silence, hemianesthesia, abdominal distention, and dry stool or constipation, has a dizzy spell, expectoration or abundant expectoration, dimly red tongue or dimness, yellow fur or yellow greasy, stringy and rolling pulse or hemiplegia side stringy and rolling pulse and large.The rule for the treatment of: reduce phlegm purging FU-organs.Main formula: star beach wormwood CHENGQI TANG " proved recipe " is added and subtracted.Side's medicine: Arisaema Cum Bile, Fructus Trichosanthis, Radix Et Rhizoma Rhei, Natrii Sulfas.As free movement of the bowels after medicine, then internal organs gas leads to, and expectorant heat subtracts, and the state of an illness has and to a certain degree takes a turn for the better.Should clearing and dissipating phlegm-heat, circulation promoting vein relaxing medicine after internal organs gas is logical, as Arisaema Cum Bile, Fructus Trichosanthis, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Caulis Spatholobi.As dizziness weight, Ramulus Uncariae Cum Uncis, Flos Chrysanthemi, Concha Margaritifera can be added.If red tongue and dysphoria, the person of lying awake all night, belong to accumulation of phlegm-heat in the interior and the deficiency of YIN of holding concurrently, the optional fresh Radix Rehmanniae, Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, Radix Scrophulariae, the Poria of adding, Caulis Polygoni Multiflori etc. educate the product that sun is calmed the nerves, but too much unsuitable, otherwise are an impediment to and wash away expectorant heat.(4) blood stasis due to qi deficiency.Syndrome: hemiplegia, crooked mouth and tongue, speech is not smoothgoing puckery or in silence, hemianesthesia, and complexion is both white, shortness of breath and fatigue, mouth sialorrhea, from sweating, cardiopalmus loose stool, brothers' swelling, dimly pale tongue, thin white fur of tongue or greasy in vain, deep-thready pulse, thin slow or thin string.The rule for the treatment of: benefiting QI for activating blood circulation.Main formula: Buyang Huanwu Decoction.Side's medicine: Radix Astragali, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Semen Persicae, Flos Carthami, Pheretima.Add the medicines such as Ramulus Mori, Squama Manis, Hirudo as hemiplegia is heavier and increase the weight of promoting blood circulation to remove obstruction in the collateral, promoting tissue regeneration by removing blood stasis effect; Aphasia notably adds Rhizoma Acori Graminei, Radix Polygalae with waking up the patient from unconsciousness by dissipating phlegm; The obvious person of brothers' swelling adds the promoting diuresis with drugs of tasteless flavour such as Poria, Rhizoma Alismatis, Semen Coicis, Radix Stephaniae Tetrandrae; Large loose stool notably goes Semen Persicae to add Rhizoma Atractylodis Macrocephalae (parched), Rhizoma Dioscoreae with spleen invigorating.(5) stirring of wind due to deficiency of YIN.Syndrome: hemiplegia, crooked mouth and tongue, stiff tongue speech is not smoothgoing or in silence, hemianesthesia, agitation is had a sleepless night, vertigo and tinnitus, feverish sensation in the palms and soles, deep red tongue or dark red, few tongue or no fur, thready and stringy pulse or thin stringy and rapid pulse.The rule for the treatment of: nourishing YIN to subdue liver-wind.Main formula: dadingfengzhu pill is added and subtracted.Side's medicine: Ovum Gallus domesticus Flavus, Colla Corii Asini, Radix Rehmanniae, Radix Ophiopogonis, the Radix Paeoniae Alba, Carapax et Plastrum Testudinis, Carapax Trionycis, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata.As hemiplegia comparatively severe one can add the product of the dredge the meridian passage such as Radix Achyranthis Bidentatae, Fructus Chaenomelis, Pheretima, Scolopendra, Ramulus Mori; Radix Salviae Miltiorrhizae, Caulis Spatholobi, Semen Persicae, eupolyphoge sinensis etc. are added with blood circulation promoting and blood stasis dispelling as dimly red tongue, hesitant pulse etc. have during syndrome of blood stasis; Dysphonia notably adds Rhizoma Acori Graminei, Radix Curcumae, Radix Polygalae sound producing profit key.
Application publication number CN104524503A(application number 201410793169.7) Chinese patent literature disclose a kind of Chinese medicine for the treatment of apoplexy, this Chinese medicine is with Radix Pedicularis Henryi 6-12 part, Radix Rehmanniae 10-25 part, Radix Rehmanniae Preparata 10-25 part, Sanguis Draxonis 10-15 part, Fructus Corni 9-15 part, Herba Cistanches 20-30 part, Radix Astragali 20-40 part, Radix Ophiopogonis 9-15 part, Rhizoma Chuanxiong 4-10 part, Radix Saposhnikoviae 6-12 part, Radix Cyathulae 9-15 part, Radix Paeoniae 5-15 part, Rhizoma Acori Graminei 4-10 part, Cortex Cinnamomi 10-15 part, Rhizoma Zingiberis Recens 5-15 part, Fructus Jujubae 2-5 part, Radix Glycyrrhizae 9-15 part is raw material, be mixed according to certain weight proportion.Application publication number CN104000931A(application number 201410244052.3) Chinese patent literature disclose a kind of medicine for the treatment of apoplexy, be made up of the component of following weight portion: Pheretima 20-30, Radix Paeoniae Rubra 6-12, Radix Ginseng 5-15, Flos Carthami 10-25, Cortex Eucommiae 20-30, blood Scorpio 10-25, Pheretima 3-8, Scolopendra 8-16, Radix Achyranthis Bidentatae 4-10, Radix Rehmanniae Preparata 8-14, Squama Manis 10-18, Radix Puerariae 10-22, Bombyx Batryticatus 6-10, Herba Lycopodii 15-25, Caulis Spatholobi 10-20, Hirudo 20-30, Radix Aconiti Lateralis Preparata 10-20, Radix Astragali 10-20, Radix Glycyrrhizae 4-10, Ramulus Cinnamomi 5-15, Radix Notoginseng powder 10-20, Herba Asari 4-10.Application publication number CN104758630A(application number 201510135611.1) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of apoplexy, its raw material of Chinese medicine and weight are: Radix Gentianae Macrophyllae 10-40 part, Ramulus Uncariae Cum Uncis 5-25 part, Herba Epimedii 10-30 part, Radix Paeoniae Alba 10-30 part, Herba Asari 5-10 part, Herba Dendrobii 10-40 part, Radix Saposhnikoviae 5-20 part, Radix Scutellariae 5-20 part, Gypsum Fibrosum 10-40 part, Herba Typhonii gigantei 5-25 part, Rhizoma Atractylodis Macrocephalae 5-20 part, Rhizoma Corydalis Decumbentis 10-30 part, Radix Rehmanniae Preparata 5-20 part, Poria 5-20 part, Radix Angelicae Pubescentis 10-30 part, Ramulus Uncariae Cum Uncis 5-25 part, Gekko Swinhonis 5-20 part, Radix Glycyrrhizae 5-15 part.
At present, the Chinese medicine and western medicine for the treatment of apoplexy has: visit aspirin, chlorine than Gray, cerebrolysin sheet, methycobal etc.This type of medicine of long-term taking can cause burden and impact to gastrointestinal, brings out the disorder of the intestines and stomach merit, digestive tract ulcer, adds cerebral hemorrhage tendency.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide the antapoplectic medicament of a kind of doctor and method for making.The present invention is evident in efficacy, and cure rate is high, and safely, have no side effect, treatment cost is low, and treating both the principal and secondary aspects of a disease not easily recurs.
Technical scheme of the present invention is:
The antapoplectic medicament of a kind of doctor, takes off the primary raw material medicine stating weight proportion and is prepared from: Fructus Jujubae 10-16, Flos Ginseng 8-15, great Ye south Soviet Union 6-14, Fructus Hordei Germinatus 9-16, Herba sagittariae pygmaeae 7-12, Fructus anacardii 8-13, Radix Gentianae Macrophyllae 10-13, Herba Rabdosiae glaucocalycis 8-14, pittosporm root 9-13, Caulis et Folium Pavettae Hongkongensis 7-14, Radix Millettiae typicae 6-13, Lysimachia trientaloides Hemsl. 9-14, adjoin Li Le 7-13, Caulis Bambusae In Taenia 10-14.
The antapoplectic medicament of a kind of doctor, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Fructus Jujubae 12-14, Flos Ginseng 10-13, great Ye south Soviet Union 8-12, Fructus Hordei Germinatus 12-14, Herba sagittariae pygmaeae 9-11, Fructus anacardii 10-12, Radix Gentianae Macrophyllae 11-12, Herba Rabdosiae glaucocalycis 11-13, pittosporm root 10-12, Caulis et Folium Pavettae Hongkongensis 9-13, Radix Millettiae typicae 9-12, Lysimachia trientaloides Hemsl. 11-13, adjoins Li Le 10-12, Caulis Bambusae In Taenia 11-13.
The antapoplectic medicament of a kind of doctor, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Fructus Jujubae 13, Flos Ginseng 12, great Ye south Soviet Union 11, Fructus Hordei Germinatus 13, Herba sagittariae pygmaeae 10, Fructus anacardii 11, Radix Gentianae Macrophyllae 11.5, Herba Rabdosiae glaucocalycis 12, pittosporm root 11, Caulis et Folium Pavettae Hongkongensis 12, Radix Millettiae typicae 11, Lysimachia trientaloides Hemsl. 12, adjoins Li Le 11, Caulis Bambusae In Taenia 12.
Present invention also offers the preparation method antapoplectic for aforementioned doctor medicament being made pharmaceutically acceptable powder, granule, pill and capsule.
The preparation method of described powder is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add two taste crude drug 9-12 water (preferably adding the water of two taste crude drug 10 times) doubly, decoct 24-30 minute (preferably decocting 27 minutes), leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. seven sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 11-13.5 times of water gaging (preferably adding 12.5 times of water gagings), heat in 65 DEG C of water-baths 32-45 minute (preferably heating 40 minutes in 65 DEG C of water-baths), leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 7-10 hour (preferably dry 8 hours), take out, altogether porphyrize powder, cross No. seven sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, add step (1) and step (2) gained medicinal liquid, stir, put into 65 DEG C of thermostatic drying chambers dry 15 hours, take out, be ground into fine powder, cross No. seven sieves, with 5g often bag subpackage, sterile packaged, to obtain final product.
The preparation method of described granule is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add two taste crude drug 9-12 water (preferably adding the water of two taste crude drug 10 times) doubly, decoct 24-30 minute (preferably decocting 27 minutes), leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. six sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 11-13.5 times of water gaging (preferably adding 12.5 times of water gagings), heat in 65 DEG C of water-baths 32-45 minute (preferably heating 40 minutes in 65 DEG C of water-baths), leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 7-10 hour (preferably dry 8 hours), take out, altogether porphyrize powder, cross No. six sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, add step (1) and step (2) gained medicinal liquid, stir, put into 65 DEG C of thermostatic drying chambers dry 15 hours, take out, be ground into fine powder, cross No. six sieves, tabletted, is then ground into granule, to obtain final product.
The preparation method of described pill is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add two taste crude drug 9-12 water (preferably adding the water of two taste crude drug 10 times) doubly, decoct 24-30 minute (preferably decocting 27 minutes), leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. six sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 11-13.5 times of water gaging (preferably adding 12.5 times of water gagings), heat in 65 DEG C of water-baths 32-45 minute (preferably heating 40 minutes in 65 DEG C of water-baths), leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 7-10 hour (preferably dry 8 hours), take out, altogether porphyrize powder, cross No. six sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, with step (1) and the general ball of step (2) gained medicinal liquid, make the pill that particle diameter is 2.5mm, the water content being dried to pill is less than 2%, to obtain final product.
The preparation method of described capsule is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add two taste crude drug 9-12 water (preferably adding the water of two taste crude drug 10 times) doubly, decoct 24-30 minute (preferably decocting 27 minutes), leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. six sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 11-13.5 times of water gaging (preferably adding 12.5 times of water gagings), heat in 65 DEG C of water-baths 32-45 minute (preferably heating 40 minutes in 65 DEG C of water-baths), leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 7-10 hour (preferably dry 8 hours), take out, altogether porphyrize powder, cross No. six sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, add step (1) and step (2) gained medicinal liquid, stir, put into 65 DEG C of thermostatic drying chambers dry 15 hours, take out, be ground into fine powder, cross No. six sieves, be filled into Capsules, every capsules is equipped with medicated powder 0.35g, to obtain final product.
The antapoplectic drug prescription science of doctor provided by the invention, the scientific matching through modern crafts is prepared from, taking convenience, is convenient to preserve, and pharmaceutical compositions is stablized.In addition, excellent results of the present invention also shows:
1, evident in efficacy, cure rate is high;
, have no side effect 2, safely;
3, treatment cost is low, relieve patient ' s burden;
4, treating both the principal and secondary aspects of a disease, not easily recurs;
5, there is dispelling wind and removing obstruction in the collateral, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, heart-calming kidney-nourishing, tonify deficiency allayed excitement, effect of removing heat-phlegm,
Effectively can treat apoplexy.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the antapoplectic medicament of a kind of doctor, the primary raw material medicine getting following weight parts is prepared from (every part is 640g): 10 parts, Fructus Jujubae, Flos Ginseng 8 parts, great Ye south Soviet Union 6 parts, 9 parts, Fructus Hordei Germinatus, Herba sagittariae pygmaeae 7 parts, Fructus anacardii 8 parts, Radix Gentianae Macrophyllae 10 parts, Herba Rabdosiae glaucocalycis 8 parts, pittosporm root 9 parts, Caulis et Folium Pavettae Hongkongensis 7 parts, Radix Millettiae typicae 6 parts, Lysimachia trientaloides Hemsl. 9 parts, adjoin Li Le 7 parts, Caulis Bambusae In Taenia 10 parts.
The preparation method of the antapoplectic medicament powder of above-mentioned doctor is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add the water of two taste crude drug 9 times, decoct 24 minutes, leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. seven sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 11 times of water gagings, heat 32 minutes in 65 DEG C of water-baths, leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 7 hours, take out, altogether porphyrize powder, cross No. seven sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, add step (1) and step (2) gained medicinal liquid, stir, put into 65 DEG C of thermostatic drying chambers dry 15 hours, take out, be ground into fine powder, cross No. seven sieves, with 5g often bag subpackage, sterile packaged, to obtain final product.
The instructions of taking that gained of the present invention cures antapoplectic medicament powder is: oral, one day twice, and each 5g, boiled water is taken after mixing it with water.
embodiment 2the antapoplectic medicament of a kind of doctor, the primary raw material medicine getting following weight parts is prepared from (every part is 640g): 16 parts, Fructus Jujubae, Flos Ginseng 15 parts, great Ye south Soviet Union 14 parts, 16 parts, Fructus Hordei Germinatus, Herba sagittariae pygmaeae 12 parts, Fructus anacardii 13 parts, Radix Gentianae Macrophyllae 13 parts, Herba Rabdosiae glaucocalycis 14 parts, pittosporm root 13 parts, Caulis et Folium Pavettae Hongkongensis 14 parts, Radix Millettiae typicae 13 parts, Lysimachia trientaloides Hemsl. 14 parts, adjoin Li Le 13 parts, Caulis Bambusae In Taenia 14 parts.
The preparation method of the antapoplectic pharmacy particle agent of above-mentioned doctor is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add the water of two taste crude drug 10 times, decoct 27 minutes, leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. six sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 12.5 times of water gagings, heat 40 minutes in 65 DEG C of water-baths, leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 8 hours, take out, altogether porphyrize powder, cross No. six sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, add step (1) and step (2) gained medicinal liquid, stir, put into 65 DEG C of thermostatic drying chambers dry 15 hours, take out, be ground into fine powder, cross No. six sieves, tabletted, is then ground into granule, to obtain final product.
model case one:lid XX, female, 64 years old.Patient have hypertension history, and before two weeks, burst left limb hemiplegia, spoken unclear, sialorrhea.Treat at local hospital and have no improvement in two weeks, then medical.Examine and see that on the left of patient, upper and lower extremities is unsuccessful, limb is soft unable, can not walk alone, shortness of breath and fatigue, mouth sialorrhea, and spoken not smoothgoing puckery, shallow complexion, dimly pale tongue, thin white fur of tongue, thready and hesitant pulse is unable.Be diagnosed as apoplexy.Take the present embodiment gained and cure antapoplectic pharmacy particle agent, three times on the one, each 8g, boiled water is taken after mixing it with water.After taking three weeks, symptom obviously alleviates, and continues to take 3 weeks, and Myodynamia recovery is normal, freedom of movement, spoken clear, takes care of oneself.Follow up a case by regular visits to and do not recur again so far.
embodiment 3the antapoplectic medicament of a kind of doctor, the primary raw material medicine getting following weight parts is prepared from (every part is 640g): 12 parts, Fructus Jujubae, Flos Ginseng 10 parts, great Ye south Soviet Union 8 parts, 12 parts, Fructus Hordei Germinatus, Herba sagittariae pygmaeae 9 parts, Fructus anacardii 10 parts, Radix Gentianae Macrophyllae 11 parts, Herba Rabdosiae glaucocalycis 11 parts, pittosporm root 10 parts, Caulis et Folium Pavettae Hongkongensis 9 parts, Radix Millettiae typicae 9 parts, Lysimachia trientaloides Hemsl. 11 parts, adjoin Li Le 10 parts, Caulis Bambusae In Taenia 11 parts.
The preparation method of the antapoplectic medicament pill of above-mentioned doctor is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add the water of two taste crude drug 10 times, decoct 27 minutes, leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. six sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 12.5 times of water gagings, heat 40 minutes in 65 DEG C of water-baths, leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 8 hours, take out, altogether porphyrize powder, cross No. six sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, with step (1) and the general ball of step (2) gained medicinal liquid, make the pill that particle diameter is 2.5mm, the water content being dried to pill is less than 2%, to obtain final product.
model case two:normal XX, man, 52 years old.Before half a year, there is the movable unfavorable symptom of aphasia companion left limb in patient, after hospital treatment, without significant change.Then medical.Examine and see that stiff tongue speech is not smoothgoing, LC face lingualis paralysis, have a dizzy spell, tongue is dark red, and thick and greasy fur is slightly yellow, stringy and rolling pulse.Be diagnosed as apoplexy.Take the present embodiment gained and cure antapoplectic medicament pill, three times on the one, each 4 balls, warm water takes.Take two weeks, aphasia companion left limb is movable unfavorable obviously to be alleviated.Continue to take 3 weeks, all diseases disappear, and language function recovers, and muscular strength is normal, and life can be taken care of oneself.Follow up a case by regular visits to and do not recur.
embodiment 4the antapoplectic medicament of a kind of doctor, the primary raw material medicine getting following weight parts is prepared from (every part is 640g): 14 parts, Fructus Jujubae, Flos Ginseng 13 parts, great Ye south Soviet Union 12 parts, 14 parts, Fructus Hordei Germinatus, Herba sagittariae pygmaeae 11 parts, Fructus anacardii 12 parts, Radix Gentianae Macrophyllae 12 parts, Herba Rabdosiae glaucocalycis 13 parts, pittosporm root 12 parts, Caulis et Folium Pavettae Hongkongensis 13 parts, Radix Millettiae typicae 12 parts, Lysimachia trientaloides Hemsl. 13 parts, adjoin Li Le 12 parts, Caulis Bambusae In Taenia 13 parts.
The preparation method of the antapoplectic drug capsule agent of above-mentioned doctor is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add the water of two taste crude drug 10 times, decoct 27 minutes, leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. six sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 12.5 times of water gagings, heat 40 minutes in 65 DEG C of water-baths, leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 8 hours, take out, altogether porphyrize powder, cross No. six sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, add step (1) and step (2) gained medicinal liquid, stir, put into 65 DEG C of thermostatic drying chambers dry 15 hours, take out, be ground into fine powder, cross No. six sieves, be filled into Capsules, every capsules is equipped with medicated powder 0.35g, to obtain final product.
model case three:for XX, man, 49 years old.Patient suffers from cerebral arteriosclerosis for many years, usually frequent dizziness headache.Before 1 week, patient's dizziness increases the weight of, and occurs that lip is numb and walk as ant, gradually the symptom such as facial hemiparalysis.Then medical.Examine and see that lip is numb, facial hemiparalysis stiff tongue, slurred speech, dizziness and headache, left side hemiplegia.Red tongue, white and thin fur, thready and stringy pulse.Be diagnosed as apoplexy.Take the present embodiment gained and cure antapoplectic drug capsule agent, three times on the one, each 2, warm water takes.Take two weeks, lip numbness and facial hemiparalysis are clearly better, and Ipsilateral upper and lower extremities is comparatively front strong.Continue to take two weeks, lip fiber crops eye tiltedly disappears, and language function recovers substantially, and hemiplegia is clearly better.After taking 1 first quarter moon, language function recovers, and life can be taken care of oneself.Follow up a case by regular visits to and do not recur.
embodiment 5the antapoplectic medicament of a kind of doctor, the primary raw material medicine getting following weight parts is prepared from (every part is 640g): 13 parts, Fructus Jujubae, Flos Ginseng 12 parts, great Ye south Soviet Union 11 parts, 13 parts, Fructus Hordei Germinatus, Herba sagittariae pygmaeae 10 parts, Fructus anacardii 11 parts, Radix Gentianae Macrophyllae 11.5 parts, Herba Rabdosiae glaucocalycis 12 parts, pittosporm root 11 parts, Caulis et Folium Pavettae Hongkongensis 12 parts, Radix Millettiae typicae 11 parts, Lysimachia trientaloides Hemsl. 12 parts, adjoin Li Le 11 parts, Caulis Bambusae In Taenia 12 parts.
The preparation method of the antapoplectic medicament powder of above-mentioned doctor is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add the water of two taste crude drug 10 times, decoct 27 minutes, leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. seven sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 12.5 times of water gagings, heat 40 minutes in 65 DEG C of water-baths, leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 8 hours, take out, altogether porphyrize powder, cross No. seven sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, add step (1) and step (2) gained medicinal liquid, stir, put into 65 DEG C of thermostatic drying chambers dry 15 hours, take out, be ground into fine powder, cross No. seven sieves, with 5g often bag subpackage, sterile packaged, to obtain final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Fructus Jujubae: base is former: be the fruit of Rhamnaceae plant Fructus Jujubae.The property of medicine: sweet; Temperature.Return spleen, stomach warp.Function cures mainly: tonifying the spleen and stomach, replenishing QI and blood, tranquilizing mind, adjusts battalion to defend, and the property of medicine.Main weakness of the spleen and stomach, insufficiency of vital energy and blood, anorexia and loose stool, fatigue and weakness, palpitation and insomnia, woman hysteria, disharmony of nutrient QI with defensive QI.
Flos Ginseng: base is former: be the inflorescence of Araliaceae Radix Ginseng.Function cures mainly: QI invigorating is kept fit; Slow down aging.Main giddy is weak; Sensation of oppression over the chest with shortness of breath." Chinese medicinal herbal ": with after brown sugar system, makes tea secondary, has excitation.
Large Ye Nansu: base is former: be the Herb of the large Ye Nansu of aroid.The property of medicine: bitter in the mouth; Micro-sweet; Cool in nature.Function cures mainly: eliminating stasis to stop pain, relaxing muscles and tendons and activating QI and blood in the collateral, nourishing the lung to arrest cough.Main angina pectoris, treating swelling and pain by traumatic injury, fracture, rheumatalgia, numb limbs and tense tendons, bronchitis, pertussis.
Fructus Hordei Germinatus: another name great Mai Nie, wheat Nie, Fructus Hordei Vulgaris hair, Fructus Hordei Germinatus are the germination caryopsis of grass Fructus Hordei Vulgaris.The property of medicine: sweet; Flat.Return spleen, stomach warp.Function cures mainly: promoting digestion and removing stagnation; Galactopoiesis.Staple food is long-pending not to disappear, and abdominal distention is had loose bowels, nausea and vomiting, inappetence, and milk smoulders, distending pain of the breast.
Herba sagittariae pygmaeae: base is former: be the herb of the short Rhizoma sagittariae sagittifoliae of Notes On Alism At Aceae.The property of medicine: lightly seasoned; Cold in nature.Return spleen channel.Function cures mainly: removing heat from the lung and relieving sorethroat; Eliminating damp, detoxifying.Main cough due to lung-heat; Laryngopharynx swelling and pain; Urine burning pain; Carbuncle furuncle and phyma poison; Eczema; Scald; Snakebite.
Fructus anacardii: base is former: be the fruit of Anacardiaceae plant chicken Fructus anacardii.The property of medicine: sweet; Flat.Return lung meridian.Function cures mainly: nourishing the lung to arrest cough; Quench the thirst; Relieving restlessness.Main cough with dyspnea; Vexed; Thirsty.
Radix Gentianae Macrophyllae: base is former: be the dry root of gentianaceae plant Radix Gentianae Macrophyllae, gentiana straminea maxim, gentiana crassicaulis Duthie or Gentiana dahurica.The property of medicine: pungent, bitter, flat.Return stomach, liver, gallbladder meridian.Function cures mainly: wind-damp dispelling, clearing away damp-heat, stopping numbness pain.For rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, and day feeds hectic fever, and infantile malnutrition generates heat.
Herba Rabdosiae glaucocalycis: base is former: be the aerial parts of labiate Herba Rabdosiae glaucocalycis.The property of medicine: acrid in the mouth; Bitter; Cool in nature.Return liver, kidney channel.Function cures mainly: clearing away heat-damp and promoting diuresis; Promoting blood circulation to remove blood stasis; Removing toxic substances and promoting subsidence of swelling.Main jaundice due to damp-heat; Stranguria; Edema; Laryngopharynx swelling and pain; Arthralgia; Amenorrhea; Acute mastitis; Hemorrhoid; Carbuncle on the back; Traumatic injury; Venom.
Pittosporm root: base is former: be root, the root bark of Pittosporaceae Chart database plant sea gold.The property of medicine: bitter, pungent, temperature.Function cures mainly: activating collaterals to relieve pain, heart-calming kidney-nourishing, removing toxic substances.Cure mainly rheumatic arthralgia, fracture, stomachache, insomnia, seminal emission, venom.
Caulis et Folium Pavettae Hongkongensis: base is former: be the stem and leaf of dicotyledon medicine Maguireothamnus speciosus Caulis et Folium Pavettae Hongkongensis.The property of medicine: bitter, pungent; Cold.GUIXIN, spleen channel.Function cures mainly: heat-clearing and toxic substances removing; Blood circulation promoting and blood stasis dispelling.Main cold, fever; Heatstroke; Hepatitis; Traumatic injury; Pathogenic wind toxic mange.
Radix Millettiae typicae: base is former: for pulse family Millettia plant dredges root and the leaf of leaf U.S. flower precipice bean rattan.The property of medicine: sweet, bitter, micro-pungent, flat.Function cures mainly: dissipating blood stasis for subsidence of swelling, and tonify deficiency is allayed excitement.Cure mainly treating swelling and pain by traumatic injury, rheumatic arthritis, weak after being ill, dyspepsia, sore swollen toxin, rubella is itched.Compatibility and incompatibility of drugs: " Hunan medicine will ": " take vomiting more.Be not taken by pregnant women.”
Lysimachia trientaloides Hemsl.: base is former: be herb or the root of the narrow leaf Herba lysimachiae Paridiformis of Primulaceae Herba Lysimachiae Fortunei platymiscium.The property of medicine: pungent, temperature.Function cures mainly: dispelling wind and removing obstruction in the collateral, promoting blood circulation and stopping pain.Cure mainly rheumatic arthralgia, hemiplegia, infantile convulsion, traumatic injury, fracture.
Adjoin Li Le: base is former: be the fruit making monarch Yu Ke plant adjoin Li Le.The property of medicine: bitter in the mouth; Micro-puckery; Cold in nature.Function cures mainly: resolving toxin and disinhibiting the throat; Cough-relieving dysentery relieving; Nourishing blood and hemoslasis.Main laryngopharynx swelling and pain; Cough; Dysentery; Bleeding hemorrhoids; Metrorrhagia; Body is empty after being ill.
Caulis Bambusae In Taenia: base is former: the intermediate layer that the stem stalk for grass family Phyllostachys plant phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle, the blue or green pole bamboo of Thorny Sinobambusa plant, Sinocalamus plant major part allusion quotation bamboo etc. goes crust to scrape.Composition: the Caulis Bambusae In Taenia of phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle is containing phenolic constituent: 2,5-dimethoxy-1,4-benzoquinone, hydroxy benzaldehyde, syringic aldehyde, coniferyl aldehyde.Another containing p-phthalic acid 2 '-hydroxyethyl methyl ester.The property of medicine: sweet, is slightly cold.Return spleen, stomach, gallbladder meridian.Function cures mainly: removing heat-phlegm, relieves restlessness and prevents vomiting, antiabortive removing heat from blood.Cure mainly cough due to lung-heat, dysphoria with smothery sensation is palpitated with fear, and gastric heat is vomitted oh, pregnancy reactions, frequent fetal movement, spits blood, epistaxis, hematuria, metrorrhagia.
test example 1gained of the present invention cures the clinical practice of antapoplectic medicament (embodiment 5): in November ,-2010 in July, 2009, screen 270 routine paralytics in 3 hospitals.Be divided into two groups at random, experimental group and matched group.Experimental group male 75 example, women 60 example, oldest 76 years old, minimum 42 years old of age, 62.5 years old mean age.Matched group male 75 example, women 60 example, oldest 76 years old, minimum 42 years old of age, 63 years old mean age.The physical data no significant difference such as two groups of case sexes, age, state of an illness, have comparability (P > 0.05).
Therapeutic Method: experimental group uses gained of the present invention to cure antapoplectic medicament, using method: oral, one day twice, and each 5g, boiled water is taken after mixing it with water.Matched group uses the Drug therapys such as QINGKAILING, XINGNAOJING ZHUSHEYE, cow-bezoar bolus for resurrection, within 10 days, is a course for the treatment of.After two groups of patients all treat four courses for the treatment of, carry out Comparison of therapeutic.
Curative effect situation criterion: clinical cure: clinical symptoms and sign disappear, and substantially can live on one's own life; Take a turn for the better: clinical symptoms and sign take a turn for the better, the action of energy cane, or substantially can live on one's own life; Invalid: clinical symptoms and sign unchanged.Always effectively comprise clinical cure and improvement, result is as shown in table 1.
Table 1: gained of the present invention cures the checking of antapoplectic pharmacy effect
Efficacy analysis: after two groups of cases treat four courses for the treatment of, experimental group clinical cure 92 example, take a turn for the better 40 examples, invalid 3 examples, total effective rate 97.78%; Matched group clinical cure 40 example, take a turn for the better 66 examples, invalid 29 examples, total effective rate 78.52%.The cure rate of experimental group and total effective rate are apparently higher than matched group.The clinical efficacy of experimental group is obviously better than matched group.
The present invention is primary raw material medicine with Fructus Jujubae, Flos Ginseng, large Ye Nansu and Fructus Hordei Germinatus etc., makes the antapoplectic medicament of doctor.Fructus Jujubae tonifying the spleen and stomach in side, replenishing QI and blood, tranquilizing mind, adjusts battalion to defend, and the property of medicine.Flos Ginseng's QI invigorating is kept fit; Slow down aging.Large Ye Nansu eliminating stasis to stop pain, relaxing muscles and tendons and activating QI and blood in the collateral, nourishing the lung to arrest cough.Fructus Hordei Germinatus promoting digestion and removing stagnation; Galactopoiesis.Herba sagittariae pygmaeae removing heat from the lung and relieving sorethroat; Eliminating damp, detoxifying.Fructus anacardii nourishing the lung to arrest cough; Quench the thirst; Relieving restlessness.Radix Gentianae Macrophyllae wind-damp dispelling, clearing away damp-heat, stopping numbness pain.Herba Rabdosiae glaucocalycis clearing away heat-damp and promoting diuresis; Promoting blood circulation to remove blood stasis; Removing toxic substances and promoting subsidence of swelling.Pittosporm root activating collaterals to relieve pain, heart-calming kidney-nourishing, removing toxic substances.Caulis et Folium Pavettae Hongkongensis heat-clearing and toxic substances removing; Blood circulation promoting and blood stasis dispelling.Radix Millettiae typicae dissipating blood stasis for subsidence of swelling, tonify deficiency is allayed excitement.Lysimachia trientaloides Hemsl. dispelling wind and removing obstruction in the collateral, promoting blood circulation and stopping pain.Adjoin Li Le resolving toxin and disinhibiting the throat; Cough-relieving dysentery relieving; Nourishing blood and hemoslasis.Caulis Bambusae In Taenia removing heat-phlegm, relieves restlessness and prevents vomiting, antiabortive removing heat from blood.Many medicines share, and mutually coordinate, and play dispelling wind and removing obstruction in the collateral altogether, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, heart-calming kidney-nourishing, tonify deficiency are allayed excitement, the effect of removing heat-phlegm, effectively can treat apoplexy.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. cure an antapoplectic medicament, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Fructus Jujubae 10-16, Flos Ginseng 8-15, great Ye south Soviet Union 6-14, Fructus Hordei Germinatus 9-16, Herba sagittariae pygmaeae 7-12, Fructus anacardii 8-13, Radix Gentianae Macrophyllae 10-13, Herba Rabdosiae glaucocalycis 8-14, pittosporm root 9-13, Caulis et Folium Pavettae Hongkongensis 7-14, Radix Millettiae typicae 6-13, Lysimachia trientaloides Hemsl. 9-14, adjoins Li Le 7-13, Caulis Bambusae In Taenia 10-14.
2. the antapoplectic medicament of doctor as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Fructus Jujubae 12-14, Flos Ginseng 10-13, great Ye south Soviet Union 8-12, Fructus Hordei Germinatus 12-14, Herba sagittariae pygmaeae 9-11, Fructus anacardii 10-12, Radix Gentianae Macrophyllae 11-12, Herba Rabdosiae glaucocalycis 11-13, pittosporm root 10-12, Caulis et Folium Pavettae Hongkongensis 9-13, Radix Millettiae typicae 9-12, Lysimachia trientaloides Hemsl. 11-13, adjoins Li Le 10-12, Caulis Bambusae In Taenia 11-13.
3. the antapoplectic medicament of doctor as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Fructus Jujubae 13, Flos Ginseng 12, great Ye south Soviet Union 11, Fructus Hordei Germinatus 13, Herba sagittariae pygmaeae 10, Fructus anacardii 11, Radix Gentianae Macrophyllae 11.5, Herba Rabdosiae glaucocalycis 12, pittosporm root 11, Caulis et Folium Pavettae Hongkongensis 12, Radix Millettiae typicae 11, Lysimachia trientaloides Hemsl. 12, adjoins Li Le 11, Caulis Bambusae In Taenia 12.
4. the antapoplectic medicament of doctor as described in as arbitrary in claims 1 to 3, it is characterized in that, antapoplectic for this doctor medicament is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add two taste crude drug 9-12 water doubly, decoct 24-30 minute, leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. seven sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 11-13.5 times of water gaging (preferably adding 12.5 times of water gagings), heat 32-45 minute in 65 DEG C of water-baths, leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 7-10 hour (preferably dry 8 hours), take out, altogether porphyrize powder, cross No. seven sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, add step (1) and step (2) gained medicinal liquid, stir, put into 65 DEG C of thermostatic drying chambers dry 15 hours, take out, be ground into fine powder, cross No. seven sieves, with 5g often bag subpackage, sterile packaged, to obtain final product.
5. the antapoplectic medicament of doctor as described in as arbitrary in claims 1 to 3, it is characterized in that, antapoplectic for this doctor medicament is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add two taste crude drug 9-12 water (preferably adding the water of two taste crude drug 10 times) doubly, decoct 24-30 minute (preferably decocting 27 minutes), leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. six sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 11-13.5 times of water gaging (preferably adding 12.5 times of water gagings), heat in 65 DEG C of water-baths 32-45 minute (preferably heating 40 minutes in 65 DEG C of water-baths), leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 7-10 hour (preferably dry 8 hours), take out, altogether porphyrize powder, cross No. six sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, add step (1) and step (2) gained medicinal liquid, stir, put into 65 DEG C of thermostatic drying chambers dry 15 hours, take out, be ground into fine powder, cross No. six sieves, tabletted, is then ground into granule, to obtain final product.
6. the antapoplectic medicament of doctor as described in as arbitrary in claims 1 to 3, it is characterized in that, antapoplectic for this doctor medicament is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add two taste crude drug 9-12 water (preferably adding the water of two taste crude drug 10 times) doubly, decoct 24-30 minute (preferably decocting 27 minutes), leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. six sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 11-13.5 times of water gaging (preferably adding 12.5 times of water gagings), heat in 65 DEG C of water-baths 32-45 minute (preferably heating 40 minutes in 65 DEG C of water-baths), leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 7-10 hour (preferably dry 8 hours), take out, altogether porphyrize powder, cross No. six sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, with step (1) and the general ball of step (2) gained medicinal liquid, make the pill that particle diameter is 2.5mm, the water content being dried to pill is less than 2%, to obtain final product.
7. the antapoplectic medicament of doctor as described in as arbitrary in claims 1 to 3, it is characterized in that, antapoplectic for this doctor medicament is made pharmaceutically acceptable capsule, and the preparation method of described capsule is:
(1) Fructus Jujubae and Fructus Hordei Germinatus are put into pot, add two taste crude drug 9-12 water (preferably adding the water of two taste crude drug 10 times) doubly, decoct 24-30 minute (preferably decocting 27 minutes), leach medicinal liquid, medicinal residues dry, and are ground into fine powder, cross No. six sieves;
(2) large Ye Nansu is dried in the shade, be ground into coarse powder, cross 30 mesh sieves, add 11-13.5 times of water gaging (preferably adding 12.5 times of water gagings), heat in 65 DEG C of water-baths 32-45 minute (preferably heating 40 minutes in 65 DEG C of water-baths), leaching medicinal liquid;
(3) all the other the 11 taste crude drug except Fructus Jujubae, large Ye Nansu and Fructus Hordei Germinatus are put into 60 DEG C of thermostatic drying chambers, dry 7-10 hour (preferably dry 8 hours), take out, altogether porphyrize powder, cross No. six sieves;
(4) by step (1) and the mixing of step (3) gained fine powder, add step (1) and step (2) gained medicinal liquid, stir, put into 65 DEG C of thermostatic drying chambers dry 15 hours, take out, be ground into fine powder, cross No. six sieves, be filled into Capsules, every capsules is equipped with medicated powder 0.35g, to obtain final product.
8. the preparation method of the antapoplectic medicament powder of doctor as claimed in claim 4, is characterized in that, add the water of two taste crude drug 10 times in step (1).
9. the preparation method of the antapoplectic medicament powder of doctor as claimed in claim 4, is characterized in that, decocts 27 minutes in step (1).
10. the preparation method of the antapoplectic medicament powder of doctor as claimed in claim 4, is characterized in that, heats 40 minutes in step (2) in 65 DEG C of water-baths.
CN201510544622.5A 2015-08-31 2015-08-31 Medicine for treating stroke and preparation method Pending CN105169117A (en)

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Citations (1)

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Publication number Priority date Publication date Assignee Title
CN103877194A (en) * 2013-10-22 2014-06-25 东南大学 Traditional Chinese medicine for treating stroke

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Publication number Priority date Publication date Assignee Title
CN103877194A (en) * 2013-10-22 2014-06-25 东南大学 Traditional Chinese medicine for treating stroke

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