CN105213894A - A kind of kidney tonifying anti-perspiration formulation and method for making for the treatment of night sweat - Google Patents

A kind of kidney tonifying anti-perspiration formulation and method for making for the treatment of night sweat Download PDF

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CN105213894A
CN105213894A CN201510677520.0A CN201510677520A CN105213894A CN 105213894 A CN105213894 A CN 105213894A CN 201510677520 A CN201510677520 A CN 201510677520A CN 105213894 A CN105213894 A CN 105213894A
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radix
herba
crude drug
dry
night sweat
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不公告发明人
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张士远
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Abstract

The invention discloses a kind of kidney tonifying anti-perspiration formulation for the treatment of night sweat, be prepared from primarily of following bulk drugs, be mass parts: Radix Codonopsis 8-14, Radix seu Folium Rubi Pinfaensis 9-15, Radix Oryzae Glutinosae 10-14, Radix Asparagi 7-15, Radix Calystegiae sepii 9-13 , Herba Siegesbeckiae 6-9, Herba Taraxaci 10-16, Herba abutili indici 8-15, Mactraantiquata Spengler 6-12, Radix Tinosporae 7-11, wild Pedicellus et Pericarpium Trapae 8-12, Fructus Hordei Germinatus 11-16, large Oxalis corniculata Linn. 8-13, rock preserved vegetable 9-14, Rhizoma Alismatis 7-13.Selection science of the present invention, reasonably combined plurality of Chinese material, without obvious toxic-side effects, this prescription is according to the development of Chinese medicine principle, and have the effect such as clearing away heat and nourishing YIN, strengthening superficial resistance to stop perspiration, evident in efficacy, instant effect, without obvious adverse reaction, treating both the principal and secondary aspects of a disease night sweat, is worthy to be popularized.

Description

A kind of kidney tonifying anti-perspiration formulation and method for making for the treatment of night sweat
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of kidney tonifying anti-perspiration formulation and method for making for the treatment of night sweat.
Background technology
Night sweat is a symptom name of the traditional Chinese medical science, be after falling asleep sweating abnormal, namely after waking up, antiperspirant is let out is only a kind of symptom of feature.Some night sweat patient is once sleep and night sweat go out, and some then goes out at night sweat to midnight of falling asleep, and some even firm shut my eyes is that night sweat goes out a little while.According to the clinical manifestation of night sweat patient, light-duty, medium-sized and heavy three kinds can be divided into.Night sweat can be divided into physiological and pathologic again, and the incidence rate of child's physiological night sweat is very high.It is normal with night sweat that climacteric, infectious disease, cancer, drug reaction, nerve or hormonal system are not normal etc., and doctor trained in Western medicine thinks that night sweat is that autonomic nervous dysfunction causes, and its pathogenesis is mainly caused by sympathetic nerve exaltation.The traditional Chinese medical science thinks that night sweat is many because of deficiency of YIN-blood, caused by mechanism of qi is obstructed.
Publication No. CN102441043A(application number 201110391196.8) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of night sweat, crude drug has the Radix Astragali 1 part, Fructus Schisandrae Chinensis 3 parts, Radix Salviae Miltiorrhizae 4 parts, the Radix Paeoniae Alba 3 parts, Radix Ephedrae 2 parts and Herba Leonuri 3 parts.Publication No. CN103550521A(application number 201310549362.1) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of night sweat, by Cortex Lycii, the Radix Astragali, Poria, Radix Ophiopogonis, Fructus Aurantii Immaturus, Fructus Corni, Fructus Lycii, the Pseudobulbus Bletillae (Rhizoma Bletillae), Semen Persicae, Testa sojae atricolor, Os Draconis, Radix Glycyrrhizae is made.Publication No. CN104208401A(application number 201410437228.7) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of night sweat, the raw material of Chinese medicine of following weight portion composition: Semen sojae atricolor 12-18 part, Radix Rehmanniae Preparata 10-15 part, Radix Asparagi 8-12 part, Fructus Mori 10-15 part, Galla Chinensis 3-8 part, Herba Epimedii 4-8 part, Radix Puerariae 1-3 part, Fructus Schisandrae Chinensis 5-10 part, Cortex Phellodendri 5-10 part, Carapax Et Plastrum Testudinis 2-5 part, Radix Paeoniae Alba 1-5 part, Cortex Lycii 0.5-2 part, Radix Ophiopogonis 1-3 part, Concha Haliotidis 1-5 part, Rhizoma Cibotii 1-3 part.
The formula of traditional Chinese medical science associated therapy night sweat has many, but effect is uneven, needs to be investigated, and therefore can develop a kind of determined curative effect, the traditional Chinese medical science formula of the treatment night sweat that the suitability is wide, solves existing formula Problems existing.
Summary of the invention
For the defect of prior art, the object of this invention is to provide a kind of kidney tonifying anti-perspiration formulation and the method for making of preparing treatment night sweat simple, evident in efficacy.
Technical scheme of the present invention is:
Treat a kidney tonifying anti-perspiration formulation for night sweat, be prepared from primarily of following bulk drugs, be mass parts: Radix Codonopsis 8-14, Radix seu Folium Rubi Pinfaensis 9-15, Radix Oryzae Glutinosae 10-14, Radix Asparagi 7-15, Radix Calystegiae sepii 9-13 , Herba Siegesbeckiae 6-9, Herba Taraxaci 10-16, Herba abutili indici 8-15, Mactraantiquata Spengler 6-12, Radix Tinosporae 7-11, wild Pedicellus et Pericarpium Trapae 8-12, Fructus Hordei Germinatus 11-16, large Oxalis corniculata Linn. 8-13, rock preserved vegetable 9-14, Rhizoma Alismatis 7-13.
In preferred scheme, Radix Codonopsis 10-12, Radix seu Folium Rubi Pinfaensis 11-13, Radix Oryzae Glutinosae 11-13, Radix Asparagi 9-13, Radix Calystegiae sepii 10-12 Herba Siegesbeckiae 7-8, Herba Taraxaci 12-14, Herba abutili indici 10-13, Mactraantiquata Spengler 8-10, Radix Tinosporae 8-10, wild Pedicellus et Pericarpium Trapae 9-11, Fructus Hordei Germinatus 13-14, large Oxalis corniculata Linn. 9-12, rock preserved vegetable 10-13, Rhizoma Alismatis 9-11.
Be more preferably, Radix Codonopsis 11, Radix seu Folium Rubi Pinfaensis 12, Radix Oryzae Glutinosae 12, Radix Asparagi 11, Radix Calystegiae sepii 11 , Herba Siegesbeckiae 7.5, Herba Taraxaci 13, Herba abutili indici 11.5, Mactraantiquata Spengler 9, Radix Tinosporae 9, wild Pedicellus et Pericarpium Trapae 10, Fructus Hordei Germinatus 13.5, large Oxalis corniculata Linn. 10.5, rock preserved vegetable 11.5, Rhizoma Alismatis 10.
The preparation method of described preparation decoction, step is as follows:
(1) Radix Codonopsis of section and wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry, pulverize;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1-2 hour (preferred, soaks 1.5 hours), pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, taking-up, removes Folium Allii tuberosi leaf, dries, pulverizing;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, decocting in water is added together with step (2) made crude drug, doubly (preferred, the 7-8 that amount of water is boiled crude drug quality doubly for the 6-9 that amount of water is boiled crude drug quality; Be more preferably, amount of water is 7.5 times of boiled crude drug quality), after boiling, little fire is decocted, and then collects medicinal liquid;
(5) join in step (4) made medicinal liquid by step (1) (3) made medicated powder, mixing, obtains decoction.
Described a kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation decoction of night sweat, the rear little fire of step (4) boiling decocts 20-34 minute, and (preferred, 24-30 minute decocted by little fire; Be more preferably, little fire decocts 27 minutes).
The preparation method of described preparation powder, step is as follows:
(1) Radix Codonopsis of section, wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1-2 hour (preferred, soaks 1.5 hours), pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, taking-up, removes Folium Allii tuberosi leaf, dries;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, pulverize and sieve together with step (1) (2) (3) made raw material, make medicated powder, obtain powder.
Described a kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation powder of night sweat, step (4) was pulverized 90-150 mesh sieve and (preferably, was pulverized 100-140 mesh sieve; Be more preferably, pulverized 120 mesh sieves).
The preparation method of described preparation pill, step is as follows:
(1) Radix Codonopsis of section, wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry, pulverize;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1-2 hour (preferred, soaks 1.5 hours), pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, taking-up, removes Folium Allii tuberosi leaf, dries, pulverizing;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, add decocting in water together with step (2) made crude drug, the rear little fire of boiling decocts 20-34 minute, and (preferred, 24-30 minute decocted by little fire; Be more preferably, little fire decocts 27 minutes), then collect medicinal liquid, medicinal residues add water and boil, and twice amount of water is 7.5 times of boiled crude drug quality, merge medicinal liquid, and are condensed into clear paste;
(5) step (1) (3) made medicated powder and step (4) made clear paste are mixed, add that refined honey is general makes ball, dry, sterilizing, obtains pill.
Described a kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation pill of night sweat, the relative density of step (4) clear paste is 1.20-1.26(70 DEG C) (preferred, the relative density of clear paste is 1.22-1.24; Be more preferably, the relative density of clear paste is 1.23).
The preparation method of described formulation tablet, step is as follows:
(1) Radix Codonopsis of section, wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry, pulverize;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1-2 hour (preferred, soaks 1.5 hours), pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, taking-up, removes Folium Allii tuberosi leaf, dries, pulverizing;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, add decocting in water together with step (2) made crude drug, the rear little fire of boiling decocts 20-34 minute, and (preferred, 24-30 minute decocted by little fire; Be more preferably, little fire decocts 27 minutes), then collect medicinal liquid, medicinal residues add water and boil, and twice amount of water is 7.5 times of boiled crude drug quality, merge medicinal liquid, and to be condensed into relative density be 1.24(70 DEG C) clear paste;
(5) step (1) (3) made medicated powder and step (4) made clear paste are mixed, dry, pulverize, add adjuvant soft material, granulate, dry, granulate, tabletting, obtains tablet.
Described a kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation tablet of night sweat, step (5) was pulverized 70-110 mesh sieve and (preferably, was pulverized 80-100 mesh sieve; Be more preferably, pulverized 90 mesh sieves).
A kind of kidney tonifying anti-perspiration formulation for the treatment of night sweat provided by the invention obtains according to clinical empirical summary for many years, and reasonable recipe, prepares simple and easy, and multiple dosage form is easy to carry.In addition, excellent results of the present invention also shows:
1, selection science of the present invention, reasonably combined plurality of Chinese material, without any side effects;
2, this prescription is according to the development of Chinese medicine principle, has the effect such as clearing away heat and nourishing YIN, strengthening superficial resistance to stop perspiration;
3, the present invention is evident in efficacy, instant effect, and without obvious adverse reaction, treating both the principal and secondary aspects of a disease night sweat, is worthy to be popularized.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Codonopsis: base is former: be the root of Campanulaceae Radix Codonopsis.Nature and flavor: sweet are flat.Gui Jing: return spleen, lung meridian.Function cures mainly: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
Radix seu Folium Rubi Pinfaensis: base is former: be root and the leaf of the red hair Fructus Rubi corchorifolii Immaturus of rosaceous plant.Nature and flavor: acid is salty, cool.Gui Jing: liver, kidney channel.Function cures mainly: cooling blood for hemostasis, expelling wind and removing dampness, detoxification sore treatment.Main heat in blood is spitted blood, and hematuria, has blood in stool, metrorrhagia, rheumatic arthritis, scrofula, eczema, leukorrhagia.
Radix Oryzae Glutinosae: base is former: be the root and rhizome of grass Oryza sativa L. var. glutinosa Matsum..Nature and flavor: sweet are flat.Gui Jing: liver.Function cures mainly: yin nourishing heat extraction, hidroschesis.Main fever due to yin deficiency, spontaneous sweating, thirsty and dry pharynx, hepatitis, filaricide.
Radix Asparagi: base is former: be the tuber of liliaceous plant Radix Asparagi.Nature and flavor: sweetness and bitterness, cold.Gui Jing: enter lung, kidney channel.Function cures mainly: YIN nourishing, moisturizes, lung heat clearing, pathogenic fire reducing.Control fever due to yin deficiency, cough is spitted blood, and consumptive lung disease, lung abscess, laryngopharynx swelling and pain, quenches one's thirst, constipation.
Radix Calystegiae sepii: base is former: be the root of convolvulaceous plant bellbine.Nature and flavor: sweet, micro-hardship, temperature.Gui Jing: lung, liver, kidney channel.Function cures mainly: QI invigorating tonify deficiency, reunion of fractured tendons and bones, removing toxic substances, parasite killing.Main erysipelas, strain, incised wound, ascariasis.
Herba Siegesbeckiae: base is former: be the herb of feverfew Herba Siegesbeckiae, Herba Siegesbeckiae or siegesbeckia glabrescens Makino.Nature and flavor: bitter, cold.Gui Jing: enter liver,spleen,kidney warp.Function cures mainly: wind-damp dispelling, relieving rigidity of muscles and joints, blood pressure lowering.Control quadriplegia, bones and muscles pain, weakness of the waist and knees, malaria, acute hepatitis, hypertension, furuncle swelling toxin, traumatic hemorrhage.
Herba Taraxaci: base is former: be the whole herb with root of feverfew Herba Taraxaci.Nature and flavor: bitter sweet, cold.Gui Jing: enter liver, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, diuresis eliminating stagnation.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.
Herba abutili indici: base is former: be the herb of Malvaceae plant Herba abutili indici.Nature and flavor: sweet, light are flat.Function cures mainly: wind and heat dispersing, and QI invigorating is sensible, diuresis of eliminating the phlegm.For flu, heat of a specified duration is not moved back, mumps, tinnitus, deaf, pulmonary tuberculosis, dysuria.
Mactraantiquata Spengler: base is former: be the meat of Carnis Mactrae section animal Mactraantiquata Spengler.Nature and flavor: sweet in the mouth, salty, property is put down.Gui Jing: Liver Channel.Function cures mainly: nourishing YIN and benefiting blood, the cool liver of heat clearing away.Main Liver and kidney clothes are empty, and the acid of waist knee joint is heavy, and conjunctival congestion, quenches one's thirst
Radix Tinosporae: base is former: be the tuber of menispermaceous plants Radix Tinosporae or limacia sagittata.Nature and flavor: bitter, cold.Gui Jing: return lung, large intestine channel.Function cures mainly: heat-clearing and toxic substances removing, sore-throat relieving, pain relieving.For laryngopharynx swelling and pain, carbuncle furunculosis, has loose bowels, dysentery, gastral cavity abdomen burning pain.
Wild Pedicellus et Pericarpium Trapae: base is former: be the nut of the wild Pedicellus et Pericarpium Trapae of Trapaceae plant and Trapa maxinowiczii Korshinsky..Nature and flavor: sweet in the mouth, property is put down.Gui Jing: return spleen, stomach warp.Function cures mainly: spleen reinforcing stomach invigorating, promoting the production of body fluid to quench thirst, removing toxic substances and promoting subsidence of swelling.Main weakness of the spleen and stomach, has loose bowels, dysentery, summer-heat excessive thirst, insobriety, and skin ulcer swells.
Fructus Hordei Germinatus: base is former: be the Fructus Hordei Vulgaris caryopsis germinateed.Nature and flavor: sweet are flat.Gui Jing: return spleen, stomach warp.Function cures mainly: promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back newborn relieving distension.Do not disappear for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, distending pain of the breast, and women weans.
Large Oxalis corniculata Linn.: base is former: be root or the herb of polygonaceae plant Rheum hastatus D. Don..Nature and flavor: acid are puckery, micro-pungent, warm in nature.Function cures mainly: relieving the exterior syndrome by diaphoresis, expelling wind and removing dampness, cough-relieving, hemostasis.Main flu, headache, rheumatic arthritis, cough with asthma, traumatic injury, metrorrhagia.
Rock preserved vegetable: base is former: be the herb of the sub-Acanthaceous indigo of acanthaceous plant four.Nature and flavor: acrid in the mouth, micro-hardship, cold in nature.Function cures mainly: dispelling wind and heat pathogens, active, removing toxic substances.Main anemopyretic cold, rheumatic ostalgia, traumatic injury, furuncle toxic swelling.
Rhizoma Alismatis: base is former: be the tuber of Notes On Alism At Aceae Rhizoma Alismatis.Nature and flavor: sweet, cold.Gui Jing: return kidney, urinary bladder channel.Function cures mainly: diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria, hyperlipidemia.
embodiment 1treat a kidney tonifying anti-perspiration formulation for night sweat, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Codonopsis 8 parts, Radix seu Folium Rubi Pinfaensis 9 parts, Radix Oryzae Glutinosae 10 parts, Radix Asparagi 7 parts, Radix Calystegiae sepii 9 parts of Herba Siegesbeckiae 6 parts, Herba Taraxaci 10 parts, Herba abutili indici 8 parts, Mactraantiquata Spengler 6 parts, Radix Tinosporae 7 parts, wild Pedicellus et Pericarpium Trapae 8 parts, 11 parts, Fructus Hordei Germinatus, large Oxalis corniculata Linn. 8 parts, rock preserved vegetable 9 parts, Rhizoma Alismatis 7 parts.
Above-mentioned a kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation decoction of night sweat is:
(1) Radix Codonopsis of section and wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry, pulverize;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1.5 hours, pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, take out, remove Folium Allii tuberosi leaf, dry, pulverizing;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, decocting in water is added together with step (2) made crude drug, amount of water is 7.5 times of boiled crude drug quality, and after boiling, little fire decocts 27 minutes, then collects medicinal liquid;
(5) join in step (4) made medicinal liquid by step (1) (3) made medicated powder, mixing, obtains decoction.
embodiment 2treat a kidney tonifying anti-perspiration formulation for night sweat, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Codonopsis 14 parts, Radix seu Folium Rubi Pinfaensis 15 parts, Radix Oryzae Glutinosae 14 parts, Radix Asparagi 15 parts, Radix Calystegiae sepii 13 parts of Herba Siegesbeckiae 9 parts, Herba Taraxaci 16 parts, Herba abutili indici 15 parts, Mactraantiquata Spengler 12 parts, Radix Tinosporae 11 parts, wild Pedicellus et Pericarpium Trapae 12 parts, 16 parts, Fructus Hordei Germinatus, large Oxalis corniculata Linn. 13 parts, rock preserved vegetable 14 parts, Rhizoma Alismatis 13 parts.
A kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation powder of night sweat is:
(1) Radix Codonopsis of section, wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1.5 hours, pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, taking-up, removes Folium Allii tuberosi leaf, dries;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, pulverized 120 mesh sieves together with step (1) (2) (3) made raw material, make medicated powder, obtain powder.
Model case: xxx, female, 46 years old.Main suit: before in menstruation, in nearly, normal sense is had a dizzy spell, night dripping sweat, perspiration stopped of waking up, but feel weak all over, with soreness of the waist and knees, extremity are not warm, fatigue and weakness, emotion is irritated, and insomnia is easily waken up, dry mouth with bitter taste, the malaise symptoms such as to be hard and dry, examination in hospital, red tongue, yellow fur is thin, wiry and frequent pulse, is diagnosed as climacteric night sweat.
Take a kind of kidney tonifying anti-perspiration formulation powder for the treatment of night sweat of the present embodiment gained, every day 2 times, each 4-6g, warm boiled water, 7 days courses for the treatment of.After taking 3 days, night sweat alleviates, and sleep quality improves, and soreness of the waist and knees is obviously alleviated, and after taking a course for the treatment of, night sweat stops, and other malaise symptoms also disappear completely, consolidate 3 days, drug withdrawal, follows up a case by regular visits to without recurrence after half a year.
embodiment 3treat a kidney tonifying anti-perspiration formulation for night sweat, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Codonopsis 10 parts, Radix seu Folium Rubi Pinfaensis 11 parts, Radix Oryzae Glutinosae 11 parts, Radix Asparagi 9 parts, Radix Calystegiae sepii 10 parts of Herba Siegesbeckiae 7 parts, Herba Taraxaci 12 parts, Herba abutili indici 10 parts, Mactraantiquata Spengler 8 parts, Radix Tinosporae 8 parts, wild Pedicellus et Pericarpium Trapae 9 parts, 13 parts, Fructus Hordei Germinatus, large Oxalis corniculata Linn. 9 parts, rock preserved vegetable 10 parts, Rhizoma Alismatis 9 parts.
A kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation pill of night sweat is:
(1) Radix Codonopsis of section, wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry, pulverize;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1.5 hours, pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, take out, remove Folium Allii tuberosi leaf, dry, pulverizing;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, decocting in water is added together with step (2) made crude drug, after boiling, little fire decocts 27 minutes, then medicinal liquid is collected, medicinal residues add water and boil, twice amount of water is 7.5 times of boiled crude drug quality, merges medicinal liquid, and to be condensed into density be 1.23(70 DEG C) clear paste;
(5) step (1) (3) made medicated powder and step (4) made clear paste are mixed, add that refined honey is general makes ball, dry, sterilizing, obtains pill.
Model case: xxx, man, 26 years old.Main suit: nearly 4 months appearance night sweat without obvious inducement, amount of sweat is comparatively large, and can drench clothes, perspiration stopped after waking up, and with the soreness of waist, the warm fear of cold of happiness, abdominal distention, poor appetite, body is tired weak, lusterless complexion, hospital admission, light red tongue, and tongue is white, and deep-thready pulse, is diagnosed as night sweat.
Take a kind of kidney tonifying anti-perspiration formulation pill for the treatment of night sweat of the present embodiment gained, adopt every day 2 times, each 2, with warm water delivery service, 7 days courses for the treatment of.After taking 2 days, night sweat obviously alleviates, and the tired weak elimination of body, after taking 4 days, night sweat only, eliminate by the abdominal distention soreness of waist, and other malaise symptoms disappear, after taking a course for the treatment of, patient mental is full, and extremity are strong, continues to take drug withdrawal after a course for the treatment of, follows up a case by regular visits to and do not recur after 3 months.
embodiment 4treat a kidney tonifying anti-perspiration formulation for night sweat, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Codonopsis 12 parts, Radix seu Folium Rubi Pinfaensis 13 parts, Radix Oryzae Glutinosae 13 parts, Radix Asparagi 13 parts, Radix Calystegiae sepii 12 parts of Herba Siegesbeckiae 8 parts, Herba Taraxaci 14 parts, Herba abutili indici 13 parts, Mactraantiquata Spengler 10 parts, Radix Tinosporae 10 parts, wild Pedicellus et Pericarpium Trapae 11 parts, 14 parts, Fructus Hordei Germinatus, large Oxalis corniculata Linn. 12 parts, rock preserved vegetable 13 parts, Rhizoma Alismatis 11 parts.
A kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation tablet of night sweat is:
(1) Radix Codonopsis of section, wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry, pulverize;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1.5 hours, pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, take out, remove Folium Allii tuberosi leaf, dry, pulverizing;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, decocting in water is added together with step (2) made crude drug, after boiling, little fire decocts 27 minutes, then medicinal liquid is collected, medicinal residues add water and boil, twice amount of water is 7.5 times of boiled crude drug quality, merges medicinal liquid, and to be condensed into relative density be 1.24(70 DEG C) clear paste;
(5) step (1) (3) made medicated powder and step (4) made clear paste are mixed, dry, pulverize 90 mesh sieves, and added adjuvant soft material, granulate, dry, granulate, tabletting, obtains tablet.
Model case: xxx, man, 33 years old.Main suit: nearly half a year job change, pressure increase, after sleeping night, sweating is more, with a face streaming with sweat, and namely stop after waking up, poor sleep, cold extremities with aversion to cold, pale complexion, after meal abdominal distention, defecate rare soft, and lazy speech is hypologia, and examination in hospital, is diagnosed as night sweat.
Take a kind of kidney tonifying anti-perspiration formulation tablet for the treatment of night sweat of the present embodiment gained, adopt every day 2 times, each 3, with warm water delivery service, 7 days courses for the treatment of.After taking 4 days, namely night sweat stop, sleep improvement, and after taking 6 days, abdominal distention body is tired, cold extremities with aversion to cold is eliminated, and after adhering to taking two courses for the treatment of, drug withdrawal, follows up a case by regular visits to after half a year without recurrence.
embodiment 5treat a kidney tonifying anti-perspiration formulation for night sweat, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Codonopsis 11 parts, Radix seu Folium Rubi Pinfaensis 12 parts, Radix Oryzae Glutinosae 12 parts, Radix Asparagi 11 parts, Radix Calystegiae sepii 11 parts of Herba Siegesbeckiae 7.5 parts, Herba Taraxaci 13 parts, Herba abutili indici 11.5 parts, Mactraantiquata Spengler 9 parts, Radix Tinosporae 9 parts, wild Pedicellus et Pericarpium Trapae 10 parts, 13.5 parts, Fructus Hordei Germinatus, large Oxalis corniculata Linn. 10.5 parts, rock preserved vegetable 11.5 parts, Rhizoma Alismatis 10 parts.
A kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation decoction of night sweat is:
(1) Radix Codonopsis of section and wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry, pulverize;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1.5 hours, pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, take out, remove Folium Allii tuberosi leaf, dry, pulverizing;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, decocting in water is added together with step (2) made crude drug, amount of water is 7.5 times of boiled crude drug quality, and after boiling, little fire decocts 27 minutes, then collects medicinal liquid;
(5) join in step (4) made medicinal liquid by step (1) (3) made medicated powder, mixing, obtains decoction.
test example 1a kind of clinical practice for the treatment of the kidney tonifying anti-perspiration formulation (embodiment 5) of night sweat of gained of the present invention:
In October, 2013 in JIUYUE ,-2014, filter out in the night sweat patient of 4 hospital admissions 254 example, wherein women 119 example, male 135 example, age 12-62 year, the mean age (35.8 ± 6.2) year, the course of disease 1 month-2 years.Clinical symptoms: sweating is all over, five vexed hectic fever, dizziness, nervous, limbs fatigue, become thin, tinnitus, insomnia, degradation under appetite.
Patient is divided into two groups at random, experimental group 140 example and matched group 114 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference ( p> 0.05), there is comparability.Experimental group takes products obtained therefrom of the present invention, and take every day twice (warm), each 150m1-200m1(adjusts to some extent depending on concrete condition), 7 days courses for the treatment of, treat two courses for the treatment of continuously.Matched group takes other medicine (conventional medication such as Maiwei rehmannia-root oral liquid, Bolus as a Kidney-Yin-Tonic, ZHIBAI DIHUANG WAN).Treatments period carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect situation criterion: cure: night sweat and simultaneous phenomenon disappear; Take a turn for the better: night sweat obviously alleviates, simultaneous phenomenon disappears; Invalid: after treatment, night sweat and simultaneous phenomenon are showed no improvement.Total effective rate=cure rate+improvement rate
Table 1 liang group patient treatment outcome
Two groups of therapeutic outcomes are as shown in table 1, therefrom known, and experimental group patient total effective rate is 95.7%, and the total effective rate of matched group is that 82.5%, two groups of results are compared, and there is significant difference (P < 0.05).All there is not any untoward reaction in treatments period two groups of patients.
The present invention selects the Radix Codonopsis having invigorating the spleen and replenishing QI, the Radix seu Folium Rubi Pinfaensis of expelling wind and removing dampness, the Radix Oryzae Glutinosae of yin nourishing heat extraction, the Radix Asparagi of lung heat clearing pathogenic fire reducing, the Radix Calystegiae sepii of QI invigorating tonify deficiency, wind-damp dispelling Herba Siegesbeckiae, the Herba Taraxaci of heat-clearing and toxic substances removing, the Herba abutili indici of wind and heat dispersing, the Mactraantiquata Spengler of nourishing YIN and benefiting blood, the Radix Tinosporae of relieving sore throat and pain, the wild Pedicellus et Pericarpium Trapae of spleen reinforcing stomach invigorating, the Fructus Hordei Germinatus of spleen benefiting and stimulating the appetite, the large Oxalis corniculata Linn. of expelling wind and removing dampness, the rock preserved vegetable of dispelling wind and heat pathogens, the Rhizoma Alismatis of clearing away damp-heat, multiple medicines share, and has the effect such as clearing away heat and nourishing YIN, strengthening superficial resistance to stop perspiration.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat a kidney tonifying anti-perspiration formulation for night sweat, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Radix Codonopsis 8-14, Radix seu Folium Rubi Pinfaensis 9-15, Radix Oryzae Glutinosae 10-14, Radix Asparagi 7-15, Radix Calystegiae sepii 9-13 , Herba Siegesbeckiae 6-9, Herba Taraxaci 10-16, Herba abutili indici 8-15, Mactraantiquata Spengler 6-12, Radix Tinosporae 7-11, wild Pedicellus et Pericarpium Trapae 8-12, Fructus Hordei Germinatus 11-16, large Oxalis corniculata Linn. 8-13, rock preserved vegetable 9-14, Rhizoma Alismatis 7-13.
2. a kind of kidney tonifying anti-perspiration formulation for the treatment of night sweat as claimed in claim 1, it is characterized in that, Radix Codonopsis 10-12, Radix seu Folium Rubi Pinfaensis 11-13, Radix Oryzae Glutinosae 11-13, Radix Asparagi 9-13, Radix Calystegiae sepii 10-12, Herba Siegesbeckiae 7-8, Herba Taraxaci 12-14, Herba abutili indici 10-13, Mactraantiquata Spengler 8-10, Radix Tinosporae 8-10, wild Pedicellus et Pericarpium Trapae 9-11, Fructus Hordei Germinatus 13-14, large Oxalis corniculata Linn. 9-12, rock preserved vegetable 10-13, Rhizoma Alismatis 9-11 is (preferred, Radix Codonopsis 11, Radix seu Folium Rubi Pinfaensis 12, Radix Oryzae Glutinosae 12, Radix Asparagi 11, Radix Calystegiae sepii 11, Herba Siegesbeckiae 7.5, Herba Taraxaci 13, Herba abutili indici 11.5, Mactraantiquata Spengler 9, Radix Tinosporae 9, wild Pedicellus et Pericarpium Trapae 10, Fructus Hordei Germinatus 13.5, large Oxalis corniculata Linn. 10.5, rock preserved vegetable 11.5, Rhizoma Alismatis 10).
3. the preparation method of the preparation decoction as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) Radix Codonopsis of section and wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry, pulverize;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1-2 hour (preferred, soaks 1.5 hours), pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, taking-up, removes Folium Allii tuberosi leaf, dries, pulverizing;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, decocting in water is added together with step (2) made crude drug, doubly (preferred, the 7-8 that amount of water is boiled crude drug quality doubly for the 6-9 that amount of water is boiled crude drug quality; Be more preferably, amount of water is 7.5 times of boiled crude drug quality), after boiling, little fire is decocted, and then collects medicinal liquid;
(5) join in step (4) made medicinal liquid by step (1) (3) made medicated powder, mixing, obtains decoction.
4. a kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation decoction of night sweat as claimed in claim 3, is characterized in that, after step (4) boiling, little fire is decocted 20-34 minute (preferred, 24-30 minute decocted by little fire; Be more preferably, little fire decocts 27 minutes).
5. the preparation method of the preparation powder as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) Radix Codonopsis of section, wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1-2 hour (preferred, soaks 1.5 hours), pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, taking-up, removes Folium Allii tuberosi leaf, dries;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, pulverize and sieve together with step (1) (2) (3) made raw material, make medicated powder, obtain powder.
6. a kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation powder of night sweat as claimed in claim 5, is characterized in that, step (4) pulverized 90-150 mesh sieve (preferred, pulverized 100-140 mesh sieve; Be more preferably, pulverized 120 mesh sieves).
7. the preparation method of the preparation pill as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) Radix Codonopsis of section, wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry, pulverize;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1-2 hour (preferred, soaks 1.5 hours), pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, taking-up, removes Folium Allii tuberosi leaf, dries, pulverizing;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, add decocting in water together with step (2) made crude drug, the rear little fire of boiling decocts 20-34 minute, and (preferred, 24-30 minute decocted by little fire; Be more preferably, little fire decocts 27 minutes), then collect medicinal liquid, medicinal residues add water and boil, and twice amount of water is 7.5 times of boiled crude drug quality, merge medicinal liquid, and are condensed into clear paste;
(5) step (1) (3) made medicated powder and step (4) made clear paste are mixed, add that refined honey is general makes ball, dry, sterilizing, obtains pill.
8. a kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation pill of night sweat as claimed in claim 7, is characterized in that, the relative density of step (4) clear paste is that 1.20-1.26(is preferred, and the relative density of clear paste is 1.22-1.24; Be more preferably, the relative density of clear paste is 1.23).
9. the preparation method of the formulation tablet as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) Radix Codonopsis of section, wild Pedicellus et Pericarpium Trapae, Fructus Hordei Germinatus and Radix Dauci Sativae juice are mixed thoroughly, be placed in Steam by water bath in container saturating, take out, mash, dry, pulverize;
(2) get Fructus Crotonis with Herba Siegesbeckiae yellow wine is well-done, pull out, be placed in frying pan with the Radix Asparagi of section together with Radix Tinosporae and Herba Taraxaci and heat and stir-fry, fry to have during focal spot to crude drug surface and take out, remove Fructus Crotonis, dry in the air cool;
(3) Mactraantiquata Spengler vinegar is soaked 1-2 hour (preferred, soaks 1.5 hours), pulls out, with the Folium Allii tuberosi leaf of chopping together slow fire heat and stir-fries, when frying to savory effusion, taking-up, removes Folium Allii tuberosi leaf, dries, pulverizing;
(4) Radix seu Folium Rubi Pinfaensis, Radix Oryzae Glutinosae, Radix Calystegiae sepii, Herba abutili indici, large Oxalis corniculata Linn., rock preserved vegetable and Rhizoma Alismatis are cleaned, add decocting in water together with step (2) made crude drug, the rear little fire of boiling decocts 20-34 minute, and (preferred, 24-30 minute decocted by little fire; Be more preferably, little fire decocts 27 minutes), then collect medicinal liquid, medicinal residues add water and boil, and twice amount of water is 7.5 times of boiled crude drug quality, merge medicinal liquid, and are condensed into the clear paste that relative density is 1.24;
(5) step (1) (3) made medicated powder and step (4) made clear paste are mixed, dry, pulverize, add adjuvant soft material, granulate, dry, granulate, tabletting, obtains tablet.
10. a kind of preparation method for the treatment of the kidney tonifying anti-perspiration formulation tablet of night sweat as claimed in claim 9, is characterized in that, step (5) pulverized 70-110 mesh sieve (preferred, pulverized 80-100 mesh sieve; Be more preferably, pulverized 90 mesh sieves).
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US20070041993A1 (en) * 2003-05-29 2007-02-22 Holcomb-Halstead Terri L Compositions and methods for symptomatic relief
CN101264229A (en) * 2008-04-21 2008-09-17 北京中科仁和科技有限公司 Medicaments assembly for nourishing blood and nourishing heart, promoting blood and qi circulation and preparation thereof

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