CN105125662A - Sugar alcohol composition - Google Patents
Sugar alcohol composition Download PDFInfo
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- CN105125662A CN105125662A CN201510586411.8A CN201510586411A CN105125662A CN 105125662 A CN105125662 A CN 105125662A CN 201510586411 A CN201510586411 A CN 201510586411A CN 105125662 A CN105125662 A CN 105125662A
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Abstract
The invention relates to a sugar alcohol composition. The sugar alcohol composition comprises different sugar alcohol materials and a pharmaceutical food material, and forms an oral preparation with a lactation promoting function through reasonable ratio and synergistic effect of all raw materials. The composition adopts a technical scheme that the composition is prepared from the following materials in parts by weight: 5 to 30 parts of reduced maltitol, 5 to 30 parts of reduced isomaltitol, 5 to 10 parts of sorbitol, 2 to 10 parts of erythritol, and 5 to 25 parts of Hovenia acerba.
Description
Technical field
The invention belongs to field of food, specifically the compositions of sugar alcohol raw material and medicine and food raw materials, it embodies and promotes Lactation.
Technical background
The milk of mammal secretes is the desirable food of the nascent young baby of nurture, mammal lactogenic is the physiological activity of mammary gland under various hormonal action of animal development, the necessary nutrient substance of multiple nascent young baby's growth promoter such as breast milk rich in proteins, fat, mineral, antibody, macrophage, lysozyme, complement and bifidus factor; Mammary gland is galactopoiesis organ, in mammary gland tissue secretory cell with nutrient substance various in blood for raw material, galactopoiesis is secreted in alveolar lumen generate milk in cell after, milk in glandular cell chamber is collected by the tubing of mammary gland tissue, flow to external milk ejection finally by breast duct and papillary duct, galactopoiesis and milk ejection two processes are collectively referred to as lactogenic.
Women's postpartum milk secretion is a complex physiologic process, except by multiple hormone, suck the intrinsic factor such as stimulation and affect except, also relevant with the extrinsic factor such as maternal nutrition situation, spirit, psychology, environment; Modern female life and work rhythm is nervous, nutrition dietary custom owes the factors such as science, puerpera is caused to give prominence to without milk or hypogalactia sap-shape condition puerperal, the method of front treatment female postpartum hypogalactia or hypogalactia is more, comprise the methods such as dietetic therapy, Chinese medicine and western medicine, massage, the effect of dietetic therapy lacks specification definitiveness, and chemotherapy side effect is large.
Modern medicine is thought, parent galactopoiesis and maintenance are regulated by nerve-hormone pathway; The prolacrin of anterior lobe of hypophysis secretion pregnancy duration by a large amount of estrogen of Placenta Hominis and ovarian secretion and progesterone suppress, parent divides the puerperium to decline suddenly due to progesterone content, cause prolacrin to discharge rapidly, mammary gland tissue causes galactopoiesis under prolacrin effect; After this, owing to maintaining certain level prolacrin all the time in maternal blood, lactogenic is maintained.
Chinese invention patent publication number CN101785797A discloses " a kind of promote lactogenic, increase the medicine of nutrition of breast milk and preparation method ", it is made up of Semen Vaccariae, dry yeast, Ferrous gluconate, calcium gluconate, vitamin A etc., said composition comprises Chinese crude drug and becomes to be grouped into trace element etc., supplements each trace element and vitamin is main from threpsology's angle; Chinese invention patent publication number CN102370936A discloses " a kind of Chinese medicine composition promoting lactogenic and preparation method thereof ", and it is that raw material forms by Flos Pruni mume, Cortex Kalopanacis, Fructus Tribuli, Rhizoma Wenyujin Concisum, Herba Pteridis Multifidae, embodies the effect of replenishing QI and blood lactogenesis; Chinese invention patent publication number CN1159333A discloses " a kind of oral liquid and growing method promoting lactogenic ", and it adopts Rhizoma Dioscoreae, Semen Nelumbinis, unfresh towel gourd, Fructus Lycii, Unguis Sus domestica, and the preparation such as Pericarpium Citri Reticulatae promotes the oral liquid of galactopoiesis, embodies spleen invigorating circulation of qi promoting lactogenesis effect; Chinese invention patent publication number CN1660213A discloses " a kind of oral preparation of Chinese traditional medicinal and preparation method promoting lactogenic ", it adopts Concha Ostreae extract, Radix Astragali extract and lactalbumin powder make the oral preparation of Chinese traditional medicinal promoting lactogenic, embody based on Chinese medicine extract, be aided with the nutrients such as albumen, form compositions preparation and obtain.
Tcm theory thinks that human body body fluid QI and blood homology, milk are the life of parent QI and blood, and QI and blood is fully the material base that milk generates; Parent hypogalactia reason is often divided into deficiency and excess: excess syndrome person is that body QI and blood is obstructed, functional activity of QI being not smooth, galactozemia, and lactogenic is few; Deficiency syndrome person is body deficiency of qi and blood, and essence of water and grain is biochemical not enough, and exhaustion of thin fluid to be lost blood etc. and caused body not produce milk.
The present invention has screened foodstuff sugar alcohol raw material, has formed compositions in conjunction with medicine and food raw materials under closing threpsology's guidance with theory of Chinese medical science, modern medicine, play and promote lactogenic effect, improve parent galactopoiesis, improve milk quality, have no side effect, be suitable for female postpartum hypogalactia or hypogalactia person use.
Summary of the invention
The object of the invention is to provide a kind of sugar alcohol composite, and by sugar alcohol raw material and medicine and food raw materials rational proportion, synergism, reaches promotion Lactation.
For achieving the above object, the present invention adopts technical scheme to be: a kind of embodiment promotes that the sugar alcohol composite of Lactation is made up by weight ratio of following raw material: oligosaccharide malt sugar alcohol powder 5-30 part, reduced isomaltooligosaccharide powder 5-30 part, Sorbitol powder 5-10 part, erythritol powder 2-10 part, Semen Hoveniae (Fructus Hoveniae) 5-25 part.
The composition material medicine weight portion preferably with anti-promotion Lactation consists of: 20 parts, oligosaccharide malt sugar alcohol powder, 15 parts, reduced isomaltooligosaccharide powder, 6 parts, Sorbitol powder, 3 parts, erythritol powder, Semen Hoveniae (Fructus Hoveniae) 10 parts.
In compositions of the present invention:
Oligosaccharide malt sugar alcohol powder belongs to hydrogenated starch hydrolysate, and be the hydrogenated products of corresponding Fructus Hordei Germinatus oligose, its sugariness is higher, sugar cook temperature more than 150 DEG C, its oligosaccharide malt sugar alcohol content more than 50%, reducing sugar≤0.3%, sorbitol≤0.3%; It has promotion Calcium-ion absorption, promotes bifidus bacillus breeding in gastrointestinal, improves action of enterogastric function;
Reduced isomaltooligosaccharide powder is the hydrogenated products of oligomeric isomaltose, colourless, transparent, free from extraneous odour, and its sugariness is sucrose 50%, and viscosity ratio sucrose is low, conventional sweeting agent, very easily water-soluble, is insoluble to methanol and closes ethanol, Maillard reaction does not occur.
Sorbitol powder is obtained by Reduction of Glucose, and its sugariness is suitable with glucose, has good moisture retention, as nutritive sweeteners, wetting agent, chelating agen, improves tissue repair effect.
Erythritol powder be starch after osmophilic yeast carries out enzymatic hydrolysis and fermentation in higher concentrations, filter through pasteurization, through ion exchange resin, active carbon and ultrafiltration purification, crystallization, washing dry and obtain, it is zero-calorie sweetening agent.
Semen Hoveniae (Fructus Hoveniae) is Chinese herbal medicines, and be the fruits and seeds with meat fruit stem of Rhamnaceae plant Semen Hoveniae (Fructus Hoveniae), sweet in the mouth, containing a large amount of glucose, calcium malate.
Above-mentioned sugar alcohol and the appropriate compatibility of medical material, play and promote cesarean lactation effect, is applicable to lack breast puerperal and hypogalactia person takes, and has no bibliographical information.
Below in conjunction with embodiment, the invention will be further elaborated
Embodiment 1 one kinds of sugar alcohol composites
(1) parts by weight of raw materials proportioning is as follows:
5 parts, oligosaccharide malt sugar alcohol powder, 5 parts, reduced isomaltooligosaccharide powder, 5 parts, Sorbitol powder, 2 parts, erythritol powder, Semen Hoveniae (Fructus Hoveniae) 5 parts
(2) preparation method is as follows:
1. take oligosaccharide malt sugar alcohol powder, reduced isomaltooligosaccharide powder, Sorbitol powder and erythritol powder raw material by above-mentioned weight portion, for subsequent use;
2. get Semen Hoveniae (Fructus Hoveniae) to dry, pulverize, sieve, obtain fine powder, for subsequent use;
3., by above-mentioned 1 and 2 abundant mix and blends, be prepared into powder.
Embodiment 2 one kinds of sugar alcohol composites
(1) parts by weight of raw materials proportioning is as follows:
30 parts, oligosaccharide malt sugar alcohol powder, 30 parts, reduced isomaltooligosaccharide powder, 10 parts, Sorbitol powder, 10 parts, erythritol powder, Semen Hoveniae (Fructus Hoveniae) 25 parts
(2) preparation method is as follows:
1. take oligosaccharide malt sugar alcohol powder, reduced isomaltooligosaccharide powder, Sorbitol powder and erythritol powder raw material by above-mentioned weight portion, for subsequent use;
2. get Semen Hoveniae (Fructus Hoveniae) to dry, pulverize, sieve, obtain fine powder, for subsequent use;
3., by above-mentioned 1 and 2 abundant mix and blends, add tablet customary adjuvant, tabletting.
Embodiment 3 one kinds of sugar alcohol composites
(1) parts by weight of raw materials proportioning is as follows:
20 parts, oligosaccharide malt sugar alcohol powder, 15 parts, reduced isomaltooligosaccharide powder, 6 parts, Sorbitol powder, 3 parts, erythritol powder, Semen Hoveniae (Fructus Hoveniae) 10 parts
(2) preparation method is as follows:
1. take oligosaccharide malt sugar alcohol powder, reduced isomaltooligosaccharide powder, Sorbitol powder and erythritol powder raw material by above-mentioned weight portion, for subsequent use;
2. get Semen Hoveniae (Fructus Hoveniae) to dry, pulverize, sieve, obtain fine powder, for subsequent use;
3., by above-mentioned 1 and 2 abundant mix and blends, process for producing granula is granulated routinely, obtains granule.
Experimental example 1 present composition promotes the efficacy assessments of lactogenic
1. laboratory animal and grouping
The female Pregnant rats of cleaning grade SD 50, body weight 250 ± 10 grams, random point 5 groups (blank group, model group, high, medium and low three the dosage groups of present composition tested material), often organize 10.
2. medication
Except blank group, within after all the other 4 groups of maternal rat delivery the 3rd day, give female Mus and take bromocriptine (0.5mg/kg/d), tested material is respectively organized gavage and is given the various dose present composition (tested material pure water dissolves and prepares to become and answers concentration, 3,6,12g/kg), all the other groups gavage normal saline, and each treated animal feeds water 14 days to tested material continuously.
3. Testing index and method
3.1 female Mus Prolactin content
After ZISHU birth, every nest stays 8 female Mus of confession to feed, point 14 days puerperiums, and the blood sampling of female Mus docking point, gets serum kit measurement Prolactin (PRL).
3.2 ZISHU body weight change
By to tested material the 3rd, within 7,14 days, measure ZISHU body weight, represent body weight change with every nest ZISHU average weight.
4. experimental result
4.1 present compositions affect female Mus Prolactin
Obvious on the impact of PRL level after the 14th day to tested material, three dosage groups more all have significant differences (P < 0.01) with model group, and the result prompting present composition has short breast effect, the results are shown in following table 1.
Table 1 present composition is on P of Rats RL impact in puerperal
* compare P < 0.01** with blank group and compare P < 0.01 with model group
4.2 present compositions affect ZISHU body weight
Each group of ZISHU weight ratio is measured comparatively without significant difference (P > 0.05) to after tested material the 3rd day, within 14th day, measure ZISHU body weight, three dosage groups and model group more all have significant difference (P < 0.01), the present composition on the impact of ZISHU body weight obviously, the result prompting present composition has short breast effect, the results are shown in following table 2.
Table 2 present composition affects ZISHU body weight
* compare P < 0.01** with blank group and compare P < 0.01 with model group.
Claims (3)
1. one kind is embodied the sugar alcohol composite promoting Lactation, it is characterized in that being made up by weight ratio of following raw material: oligosaccharide malt sugar alcohol powder 5-30 part, reduced isomaltooligosaccharide powder 5-30 part, Sorbitol powder 5-10 part, erythritol powder 2-10 part, Semen Hoveniae (Fructus Hoveniae) 5-25 part.
2. compositions according to claim 1, is characterized in that said composition is made up of the raw material of following weight portion: 20 parts, oligosaccharide malt sugar alcohol powder, 15 parts, reduced isomaltooligosaccharide powder, 6 parts, Sorbitol powder, 3 parts, erythritol powder, Semen Hoveniae (Fructus Hoveniae) 10 parts.
3. compositions according to claim 1, is characterized in that said composition is oral formulations.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510586411.8A CN105125662A (en) | 2015-09-07 | 2015-09-07 | Sugar alcohol composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510586411.8A CN105125662A (en) | 2015-09-07 | 2015-09-07 | Sugar alcohol composition |
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| CN105125662A true CN105125662A (en) | 2015-12-09 |
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| CN201510586411.8A Pending CN105125662A (en) | 2015-09-07 | 2015-09-07 | Sugar alcohol composition |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060057274A1 (en) * | 2004-09-16 | 2006-03-16 | Land O'lakes Farmland Feed Llc | Animal feed with a soluble fiber and sugar alcohol and method of making and method of feeding |
| CN102793736A (en) * | 2012-07-25 | 2012-11-28 | 青岛文创科技有限公司 | Buccal tablet with removing throat heat and promoting diuresis |
| CN105055495A (en) * | 2015-08-28 | 2015-11-18 | 广州国宇医药科技有限公司 | Application of campylotropis macrocarpa in preparation of milk secretion promoting product |
-
2015
- 2015-09-07 CN CN201510586411.8A patent/CN105125662A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060057274A1 (en) * | 2004-09-16 | 2006-03-16 | Land O'lakes Farmland Feed Llc | Animal feed with a soluble fiber and sugar alcohol and method of making and method of feeding |
| CN102793736A (en) * | 2012-07-25 | 2012-11-28 | 青岛文创科技有限公司 | Buccal tablet with removing throat heat and promoting diuresis |
| CN105055495A (en) * | 2015-08-28 | 2015-11-18 | 广州国宇医药科技有限公司 | Application of campylotropis macrocarpa in preparation of milk secretion promoting product |
Non-Patent Citations (3)
| Title |
|---|
| 中国科学院四川分院中医中药研究所: "《四川中药誌 第一册》", 31 January 1960, 四川人民出版社 * |
| 夏延斌等: "《食品化学》", 28 February 2015, 中国农业出版社 * |
| 陈惊蛰: "《老偏方》", 31 March 2012, 江西科学技术出版社 * |
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Application publication date: 20151209 |
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