CN105120948B - 用于控制免疫刺激的激光热疗的装置和计算机可读介质 - Google Patents

用于控制免疫刺激的激光热疗的装置和计算机可读介质 Download PDF

Info

Publication number
CN105120948B
CN105120948B CN201480023179.0A CN201480023179A CN105120948B CN 105120948 B CN105120948 B CN 105120948B CN 201480023179 A CN201480023179 A CN 201480023179A CN 105120948 B CN105120948 B CN 105120948B
Authority
CN
China
Prior art keywords
temperature
thermal sensor
sensor member
heating probe
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201480023179.0A
Other languages
English (en)
Chinese (zh)
Other versions
CN105120948A (zh
Inventor
卡尔·戈兰·特兰伯格
斯蒂芬·笛姆宁
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clinical Laserthermia Systems AB
Original Assignee
Clinical Laserthermia Systems AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clinical Laserthermia Systems AB filed Critical Clinical Laserthermia Systems AB
Priority to CN201811509556.8A priority Critical patent/CN109498152B/zh
Priority to CN201811508845.6A priority patent/CN109771030A/zh
Publication of CN105120948A publication Critical patent/CN105120948A/zh
Application granted granted Critical
Publication of CN105120948B publication Critical patent/CN105120948B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00642—Sensing and controlling the application of energy with feedback, i.e. closed loop control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00666—Sensing and controlling the application of energy using a threshold value
    • A61B2018/00678—Sensing and controlling the application of energy using a threshold value upper
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00696—Controlled or regulated parameters
    • A61B2018/00702—Power or energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00791—Temperature
    • A61B2018/00797—Temperature measured by multiple temperature sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00898—Alarms or notifications created in response to an abnormal condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B2018/2005—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser with beam delivery through an interstitially insertable device, e.g. needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B2018/2035—Beam shaping or redirecting; Optical components therefor
    • A61B2018/20361—Beam shaping or redirecting; Optical components therefor with redirecting based on sensed condition, e.g. tissue analysis or tissue movement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2255—Optical elements at the distal end of probe tips
    • A61B2018/2261—Optical elements at the distal end of probe tips with scattering, diffusion or dispersion of light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A61N2005/0612—Apparatus for use inside the body using probes penetrating tissue; interstitial probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0626—Monitoring, verifying, controlling systems and methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0626—Monitoring, verifying, controlling systems and methods
    • A61N2005/0627—Dose monitoring systems and methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/063—Radiation therapy using light comprising light transmitting means, e.g. optical fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/067—Radiation therapy using light using laser light

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Radiation-Therapy Devices (AREA)
  • Laser Surgery Devices (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Surgery (AREA)
  • Electromagnetism (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
CN201480023179.0A 2013-04-30 2014-04-30 用于控制免疫刺激的激光热疗的装置和计算机可读介质 Expired - Fee Related CN105120948B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201811509556.8A CN109498152B (zh) 2013-04-30 2014-04-30 用于控制免疫刺激的激光热疗的装置和方法
CN201811508845.6A CN109771030A (zh) 2013-04-30 2014-04-30 用于控制免疫刺激的激光热疗的装置和方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361817743P 2013-04-30 2013-04-30
EP13165962.5 2013-04-30
US61/817,743 2013-04-30
EP13165962.5A EP2799111A1 (en) 2013-04-30 2013-04-30 Apparatus and method for controlling immunostimulating laser thermotherapy
PCT/EP2014/058934 WO2014177663A1 (en) 2013-04-30 2014-04-30 Apparatus and method for controlling immunostimulating laser thermotherapy

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN201811508845.6A Division CN109771030A (zh) 2013-04-30 2014-04-30 用于控制免疫刺激的激光热疗的装置和方法
CN201811509556.8A Division CN109498152B (zh) 2013-04-30 2014-04-30 用于控制免疫刺激的激光热疗的装置和方法

Publications (2)

Publication Number Publication Date
CN105120948A CN105120948A (zh) 2015-12-02
CN105120948B true CN105120948B (zh) 2019-07-09

Family

ID=48190348

Family Applications (3)

Application Number Title Priority Date Filing Date
CN201480023179.0A Expired - Fee Related CN105120948B (zh) 2013-04-30 2014-04-30 用于控制免疫刺激的激光热疗的装置和计算机可读介质
CN201811509556.8A Active CN109498152B (zh) 2013-04-30 2014-04-30 用于控制免疫刺激的激光热疗的装置和方法
CN201811508845.6A Pending CN109771030A (zh) 2013-04-30 2014-04-30 用于控制免疫刺激的激光热疗的装置和方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201811509556.8A Active CN109498152B (zh) 2013-04-30 2014-04-30 用于控制免疫刺激的激光热疗的装置和方法
CN201811508845.6A Pending CN109771030A (zh) 2013-04-30 2014-04-30 用于控制免疫刺激的激光热疗的装置和方法

Country Status (9)

Country Link
US (3) US10960223B2 (https=)
EP (3) EP2799111A1 (https=)
JP (2) JP6709153B2 (https=)
KR (1) KR102465782B1 (https=)
CN (3) CN105120948B (https=)
AU (1) AU2014261409B2 (https=)
BR (1) BR112015027594A8 (https=)
ES (2) ES2940352T3 (https=)
WO (1) WO2014177663A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE532142C2 (sv) * 2007-09-28 2009-11-03 Clinical Laserthermia Systems Anordning för bestämning av en termisk egenskap hos en vävnad
CN104644265B (zh) * 2015-03-03 2017-10-27 中国科学院苏州生物医学工程技术研究所 具有运动和温度感应的智能激光治疗手具
CN106691675A (zh) * 2015-07-24 2017-05-24 广州保瑞医疗技术有限公司 一种血管内激光加热全身热疗仪
CN105344018A (zh) * 2015-10-13 2016-02-24 杨富云 一种微波治疗方法及其装置
FR3046546B1 (fr) * 2016-01-07 2020-12-25 Urgo Rech Innovation Et Developpement Dispositif de traitement dermatologique
AU2017211299A1 (en) * 2016-01-26 2018-08-09 The Regents Of The University Of California System for out of bore focal laser therapy
US10335607B2 (en) 2016-02-05 2019-07-02 Boston Scientific Neuromodulation Corporation Implantable optical stimulation lead and methods of making and using
US11547479B2 (en) * 2016-08-25 2023-01-10 Gyrus Acmi Inc. Automatic irrigation-coordinated lithotripsy
KR20190062419A (ko) 2016-10-04 2019-06-05 아벤트, 인크. 냉각된 rf 프로브
EP3335660B1 (en) * 2016-12-14 2021-01-20 Clinical Laserthermia Systems AB Apparatus for controlling laser thermotherapy
US20200046997A1 (en) * 2017-04-29 2020-02-13 Health Research, Inc. Method and system for concurrent photothermal ablation and interstitial photodynamic therapy
CN108325089A (zh) * 2018-01-03 2018-07-27 南通大学 一种肿瘤激光热疗和多参数实时监测探头
CN109260596A (zh) * 2018-05-29 2019-01-25 杨富云 一种微波治疗肿瘤的装置
EP3840824A1 (en) 2018-11-16 2021-06-30 Boston Scientific Neuromodulation Corporation An optical stimulation system with on-demand monitoring and methods of making
EP3685778A1 (en) * 2019-01-25 2020-07-29 Koninklijke Philips N.V. Apparatus for determining a position of a temperature probe during a planning for an ablation procedure
US12011222B2 (en) 2019-05-02 2024-06-18 Avenda Health, Inc. Interlock to define a fixed spatial relationship between medical instruments
EP4157443A1 (en) * 2020-05-29 2023-04-05 KNOW Bio, LLC Devices and related methods for light-based modulation of foreign body responses in living tissue
JP7534530B2 (ja) * 2020-07-30 2024-08-14 ボストン サイエンティフィック サイムド，インコーポレイテッド 一体型レーザファイバ冷却を有する流体管理システム
CN111986447B (zh) * 2020-08-05 2022-01-04 西北工业大学 一种微纳米温度灵敏报警器
US12427332B2 (en) 2021-04-08 2025-09-30 Boston Scientific Neuromodulation Corporation Photobiomodulation system and delivery device and methods of making and using
EP4572847A1 (en) * 2022-08-22 2025-06-25 Boston Scientific Neuromodulation Corporation Implantable photobiomodulation systems employing thermal monitoring or control and methods of making and using
EP4398258A3 (en) 2023-01-04 2024-08-28 Boston Scientific Neuromodulation Corporation Systems and methods incorporating a light therapy user interface for optical modulation
EP4725437A1 (en) 2024-10-08 2026-04-15 Clinical Laserthermia Systems AB System for thermal therapy

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5222953A (en) * 1991-10-02 1993-06-29 Kambiz Dowlatshahi Apparatus for interstitial laser therapy having an improved temperature sensor for tissue being treated
CN2574631Y (zh) * 2002-11-04 2003-09-24 中国科学院福建物质结构研究所 一种激光热疗仪探头装置
WO2009124301A1 (en) * 2008-04-03 2009-10-08 Visualase, Inc. Systems and methods for thermal therapy
CN101854876A (zh) * 2007-09-28 2010-10-06 临床激光热疗系统公司 用于确定组织特性的装置和方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6603988B2 (en) * 2001-04-13 2003-08-05 Kelsey, Inc. Apparatus and method for delivering ablative laser energy and determining the volume of tumor mass destroyed
CN85104234A (zh) * 1985-06-03 1986-11-26 吴羽化学工业株式会社 内装式温度传感器
JPH02182272A (ja) * 1988-12-14 1990-07-16 Microthermia Technol Inc 腫瘍などの細胞を破壊する装置及び方法
US5623940A (en) * 1994-08-02 1997-04-29 S.L.T. Japan Co., Ltd. Catheter apparatus with a sensor
JPH08257048A (ja) * 1995-03-24 1996-10-08 Shimadzu Corp 温熱治療装置
JP2001046389A (ja) * 1999-08-12 2001-02-20 Terumo Corp 加熱治療装置
JP3859443B2 (ja) * 2000-09-27 2006-12-20 オリンパス株式会社 加温治療装置
JP3966406B2 (ja) 2002-04-04 2007-08-29 パイオニア株式会社 プラズマディスプレイパネルのエージングトレー
US7270656B2 (en) * 2003-11-07 2007-09-18 Visualase, Inc. Cooled laser fiber for improved thermal therapy
EP1541091A1 (en) * 2003-12-10 2005-06-15 EL.EN. S.p.A. Device for treating tumors by laser thermotherapy
US7251531B2 (en) 2004-01-30 2007-07-31 Ams Research Corporation Heating method for tissue contraction
JP4504718B2 (ja) * 2004-03-31 2010-07-14 テルモ株式会社 加熱治療装置
US20070073282A1 (en) * 2005-09-26 2007-03-29 Starion Instruments Corporation Resistive heating device and method for turbinate ablation
US20080033300A1 (en) 2006-08-04 2008-02-07 Anh Hoang Systems and methods for monitoring temperature during electrosurgery or laser therapy
US9403029B2 (en) * 2007-07-18 2016-08-02 Visualase, Inc. Systems and methods for thermal therapy
FR2954690A1 (fr) * 2009-12-29 2011-07-01 Ekkyo Dispositif de traitement dermatologique par faisceau lumineux
CN101972188A (zh) * 2010-11-10 2011-02-16 韩俊江 精确控温肿瘤治疗仪及其控制方法
US9192438B2 (en) * 2011-12-21 2015-11-24 Neuwave Medical, Inc. Energy delivery systems and uses thereof
EP2866723A4 (en) * 2012-06-27 2016-12-14 Monteris Medical Corp IMAGE-guided THERAPY OF TISSUE

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5222953A (en) * 1991-10-02 1993-06-29 Kambiz Dowlatshahi Apparatus for interstitial laser therapy having an improved temperature sensor for tissue being treated
CN2574631Y (zh) * 2002-11-04 2003-09-24 中国科学院福建物质结构研究所 一种激光热疗仪探头装置
CN101854876A (zh) * 2007-09-28 2010-10-06 临床激光热疗系统公司 用于确定组织特性的装置和方法
WO2009124301A1 (en) * 2008-04-03 2009-10-08 Visualase, Inc. Systems and methods for thermal therapy

Also Published As

Publication number Publication date
US11850442B2 (en) 2023-12-26
AU2014261409B2 (en) 2019-02-21
EP2991730A1 (en) 2016-03-09
AU2014261409A1 (en) 2015-11-12
CN109498152B (zh) 2022-03-18
ES2734518T3 (es) 2019-12-10
JP7190463B2 (ja) 2022-12-15
CN105120948A (zh) 2015-12-02
US20160067519A1 (en) 2016-03-10
BR112015027594A8 (pt) 2023-03-07
JP6709153B2 (ja) 2020-06-10
WO2014177663A1 (en) 2014-11-06
BR112015027594A2 (pt) 2017-12-12
CN109771030A (zh) 2019-05-21
EP2799111A1 (en) 2014-11-05
KR20160026865A (ko) 2016-03-09
EP3335762B1 (en) 2023-01-11
KR102465782B1 (ko) 2022-11-15
CN109498152A (zh) 2019-03-22
US10960223B2 (en) 2021-03-30
US20210236839A1 (en) 2021-08-05
EP3335762A1 (en) 2018-06-20
ES2940352T3 (es) 2023-05-05
EP2991730B1 (en) 2019-04-10
US20240082596A1 (en) 2024-03-14
JP2016522024A (ja) 2016-07-28
JP2020142111A (ja) 2020-09-10

Similar Documents

Publication Publication Date Title
CN105120948B (zh) 用于控制免疫刺激的激光热疗的装置和计算机可读介质
JP2016522024A5 (https=)
Missios et al. Renaissance of laser interstitial thermal ablation
Matthewson et al. Biological effects of intrahepatic neodymium: yttrium-aluminum-garnet laser photocoagulation in rats
US20130267939A1 (en) Methods and Apparatus for Ablating Lung Nodules with Vapor
CN101854876A (zh) 用于确定组织特性的装置和方法
KR20100041753A (ko) 레이저 지방 분해용 동축 흡입 시스템
CN101166480A (zh) 激光脂肪分解方法及系统
EP4413935A2 (en) Ablation probe systems
EP4231953B1 (en) Ablation probe systems
JP2012502714A (ja) 処置用量送達手段および用量測定制御手段を実現してヒトまたは動物の身体の一部を処置するための装置および方法
Zikorus et al. Evaluation of setpoint temperature and pullback speed on vein adventitial temperature during endovenous radiofrequency energy delivery in an in-vitro model
Milne et al. Development of stereotactically guided laser interstitial thermotherapy of breast cancer: In situ measurement and analysis of the temperature field in ex vivo and in vivo adipose tissue
HK40010623B (en) Apparatus and method for controlling immunostimulating laser thermotherapy
HK40010623A (en) Apparatus and method for controlling immunostimulating laser thermotherapy
Salas Jr et al. Thermal analysis of laser interstitial thermotherapy in ex vivo fibro-fatty tissue using exponential functions
US20120065710A1 (en) Laser-Based Lipolysis
Chang et al. Using temperature–time integration as a critical parameter in using monopolar radiofrequency ablations
RU2424009C1 (ru) Устройство для проведения внутритканевой лазерной гипертермии и фотодинамической терапии и способ их осуществления
Luis et al. Optoacoustic monitoring of RF ablation lesion progression

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20190709