CN105079552A - Preparation for treating prosopalgia and preparation method - Google Patents

Preparation for treating prosopalgia and preparation method Download PDF

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CN105079552A
CN105079552A CN201510558651.7A CN201510558651A CN105079552A CN 105079552 A CN105079552 A CN 105079552A CN 201510558651 A CN201510558651 A CN 201510558651A CN 105079552 A CN105079552 A CN 105079552A
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付丽娜
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Abstract

The invention discloses a preparation for treating prosopalgia. The preparation is characterized by being prepared from the following main raw medical materials in parts by weight: 8-13 parts of caulis spatholobi, 6-12 parts of firethorn fruits, 10-14 parts of incarvillea arguta, 7-15 parts of passion flower, 6-14 parts of cordyline terminalis, 9-13 parts of jasminum grandiflorum, 8-12 parts of dioscorea collettii Hook.f., 9-15 parts of blighted wheat, 10-16 parts of polygonum japonicum, 8-14 parts of pigeon pea root, 9-16 parts of ebony, 7-14 parts of lysimachia decurrens, 9-12 parts of frankincense, 10-13 parts of crateva unilocularis, 8-15 parts of phtheirospermum tenuisectum, 6-13 parts of Carthamus tinctorus L and 9-14 parts of peach root. The preparation is prepared through years of clinical practice summary, has the efficacies of promoting qi, activating blood, dredging collaterals and relieving pain, and is obvious in curative effect.

Description

Cure prosopalgic preparation and preparation method thereof
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to and cure prosopalgic preparation and preparation method thereof.
Background technology
Trigeminal neuralgia is modal cranial nerve diseases, and with the violent pain of the paroxysmal of recurrent exerbation in a side surface part nervi trigeminus areal area for main manifestations, morbidity crowd is slightly more than man for female, and sickness rate can increase with the age.Trigeminal neuralgia is divided into constitutional and Secondary cases two kinds, and secondary trigeminal neuralgia comprises brain occupying lesion and perstriction, the cause of disease of primary trigeminal neuralgia and pathogenesis, and doctor trained in Western medicine there is no clear and definite final conclusion so far, and the traditional Chinese medical science is thought and belonged to Liver and kidney problem.Its Episodes, for suddenly to show effect, without any tendency, mostly is side.During outbreak, sharp ache is as lancinated, shocking by electricity, last for several seconds to 1-2 minute, often with facial spasm, shed tears, sialorrhea, flushed face in the afternoon, the symptom such as conjunctival congestion, along with increasing the weight of of the state of an illness, intermission is more and more short, outbreak is further frequent, through once strong pain stimulation, makes patient's psychological problem nervous, never to forget in one's life, cause great misery.
Publication No. CN103211982A(application number 201310154579.2) Chinese patent literature disclose one and treat prosopalgic medicine, it is that crude drug prepares by Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Bombyx Batryticatus, Arisaema Cum Bile, Concha Haliotidis, Fructus Atriplicis Sibiricae, Poria, Fructus Gardeniae, Cortex Moutan, Radix Paeoniae Rubra, Pheretima, Fructus Viticis, corresponding peroral dosage form can be processed into, as powder, tablet, capsule, honeyed pill etc.Publication No. CN103083507A(application number 201210529299.0) Chinese patent literature disclose one and treat prosopalgic Chinese medicine, be made up of the Radix Angelicae Dahuricae, the Radix Paeoniae Alba, Radix Glycyrrhizae, Gypsum Fibrosum, Radix Gentianae, Rhizoma Chuanxiong, Pheretima, Bombyx Batryticatus, Scorpio, Scolopendra, Herba Asari, Radix Et Rhizoma Rhei, Rhizoma Cyperi, Periostracum Cicadae.Publication No. CN103861046A(application number 201410140862.4) Chinese patent literature disclose one and treat prosopalgic Chinese medicine, this Chinese medicine is by spending schefflera in vain, Flos daphnes odorae, Caulis fici pumilae (Fructus Fici Pumilae), Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), Radix Curcumae, Fructus Citri tangerinae core, four is stupefied logical, Rhizoma Curcumae Longae, Semen Bauhiniae championii, anistree, Radix Glycyrrhizae is made.
The medicine being used for the treatment of this disease is at present main mainly with carbamazepine, but side effect is comparatively large, and be not suitable for all patients, other treatment means are relatively complicated, and the state of an illness easily recurs, and therefore needs to develop the Chinese medicine formula that a kind of determined curative effect, side effect are little.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take prosopalgic preparation of the wide treatment of safe and applicable and preparation method thereof.
Technical scheme of the present invention is:
Cure prosopalgic preparation, be prepared from primarily of following bulk drugs, be mass parts: Caulis Spatholobi 8-13; Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) 6-12; Suona horn flower 10-14; Herba Passiflorae Caeruleae 7-15; Ti 6-14; Flos jasmini 9-13; Nine sons are not from female 8-12; Fructus Tritici Levis 9-15; Herba Polygoni japonici 10-16; Semen Cajani root 8-14; Folium seu Fructus Tarennae 9-16; The careless 7-14 of scrofula; Olibanum 9-12; Tree head dish 10-13; Phtheirospermum tenuisectum Bur.et Franch. 8-15; Herba Astragali Sinici 6-13; Radix Persicae 9-14.
Preferred version is, Caulis Spatholobi 9-12; Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) 8-10; Suona horn flower 11-13; Herba Passiflorae Caeruleae 9-13; Ti 8-12; Flos jasmini 10-12; Nine sons are not from female 9-11; Fructus Tritici Levis 10-14; Herba Polygoni japonici 12-14; Semen Cajani root 10-12; Folium seu Fructus Tarennae 11-14; The careless 9-12 of scrofula; Olibanum 10-11; Tree head dish 11-12; Phtheirospermum tenuisectum Bur.et Franch. 10-13; Herba Astragali Sinici 8-11; Radix Persicae 11-12.
Be more preferably, Caulis Spatholobi 10.5; Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) 9; Suona horn spends 12; Herba Passiflorae Caeruleae 11; Ti 10; Flos jasmini 11; Nine sons are not from female 10; Fructus Tritici Levis 12; Herba Polygoni japonici 13; Semen Cajani root 11; Folium seu Fructus Tarennae 12.5; Scrofula grass 10.5; Olibanum 10.5; Tree head dish 11.5; Phtheirospermum tenuisectum Bur.et Franch. 11.5; Herba Astragali Sinici 9.5; Radix Persicae 11.5.
The prosopalgic preparation of described treatment, be made into pharmaceutically acceptable granule, its preparation method is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 12-24 minute (preferred: Steam by water bath 16-20 minute; Be more preferably: Steam by water bath 18 minutes), taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add decocting in water to boiling, continue 16-28 minute (preferably: continue 20-24 minute; Be more preferably: continue 22 minutes), Guan Huohou, filters, and collect filtrate, concentrated filtrate is to thick paste;
(5) pulverized by made to step (1) (2) (3) crude drug, mix with step (4) gained thick paste, add adjuvant, make soft material, extruding is sieved, and makes wet granular, dries granulate, obtains granule.
The preparation method of the prosopalgic preparation granules agent of described treatment, step (4) amount of water with boil crude drug mass ratio be 6:1.
The prosopalgic preparation of described treatment, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 12-24 minute (preferred: Steam by water bath 16-20 minute; Be more preferably: Steam by water bath 18 minutes), taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), heating is boiled to boiling, continues 16-28 minute (preferably: continue 20-24 minute; Be more preferably: continue 22 minutes), Guan Huohou, filters, and collects filtrate;
(5) pulverized by made to step (1) (2) (3) crude drug, mix with step (4) gained filtrate, heating is concentrated into clear paste, obtains unguentum.
The preparation method of the prosopalgic preparation unguentum of described treatment, it is (preferred: heating is concentrated into the clear paste that relative density is 1.12-1.18 that step (5) heating is concentrated into the clear paste (75 DEG C) that relative density is 1.10-1.20; Be more preferably: heating is concentrated into the clear paste that relative density is 1.15).
The prosopalgic preparation of described treatment, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 12-24 minute (preferred: Steam by water bath 16-20 minute; Be more preferably: Steam by water bath 18 minutes), taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), heating is boiled to boiling, continues 16-28 minute (preferably: continue 20-24 minute; Be more preferably: continue 22 minutes), Guan Huohou, filters, and collects filtrate;
(5) step (1) (2) (3) made crude drug is pulverized and sieved, be added in step (4) gained filtrate, heated and boiled, after filtration, collect filtrate, obtain decoction.
The preparation method of the prosopalgic preparation decoction of described treatment, it is (preferred: to pulverize 80-100 mesh sieve that step (5) pulverized 60-120 mesh sieve; Be more preferably: pulverized 90 mesh sieves).
The prosopalgic preparation of described treatment, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 12-24 minute (preferred: Steam by water bath 16-20 minute; Be more preferably: Steam by water bath 18 minutes), taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), heating is boiled to boiling, continues 16-28 minute (preferably: continue 20-24 minute; Be more preferably: continue 22 minutes), Guan Huohou, filters, and collects filtrate;
(5) concentration step (4) gained filtrate, pulverizes and sieves after drying, obtains powder together with step (1) (2) (3) made crude drug.
The preparation method of the prosopalgic preparation powder of described treatment, it is (preferred: to pulverize 140-160 mesh sieve that step (5) pulverized 120-180 mesh sieve; Be more preferably: pulverized 150 mesh sieves).
The prosopalgic pharmaceutical formulation science for the treatment of provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, effectively can prevent recurrent pain;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of promoting flow of QI and blood, dissipating blood stasis analgesic therapy;
3, Chinese crude drug selected by the present invention, takes safety, and side effect is little, is applicable to all patients.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1cure prosopalgic preparation, be prepared from (every part of 10g) primarily of following bulk drugs: Caulis Spatholobi 8 parts, Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) 6 parts, suona horn spends 10 parts, Herba Passiflorae Caeruleae 7 parts, ti 6 parts, Flos jasmini 9 parts, nine sons not from female 8 parts, Fructus Tritici Levis 9 parts, Herba Polygoni japonici 10 parts, Semen Cajani root 8 parts, Folium seu Fructus Tarennae 9 parts, scrofula grass 7 parts, Olibanum 9 parts, tree head dish 10 parts, Phtheirospermum tenuisectum Bur.et Franch. 8 parts, Herba Astragali Sinici 6 parts, Radix Persicae 9 parts.The preparation method of the prosopalgic preparation granules agent of above-mentioned treatment is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 18 minutes, taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add decocting in water to boiling (amount of water with boil crude drug mass ratio be 6:1), continue 22 minutes, Guan Huohou, filter, collect filtrate, concentrated filtrate is to thick paste;
(5) pulverized by made to step (1) (2) (3) crude drug, mix with step (4) gained thick paste, add adjuvant, make soft material, extruding is sieved, and makes wet granular, dries granulate, obtains granule.
embodiment 2cure prosopalgic preparation, be prepared from (every part of 10g) primarily of following bulk drugs: Caulis Spatholobi 13 parts, Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) 12 parts, suona horn spends 14 parts, Herba Passiflorae Caeruleae 15 parts, ti 14 parts, Flos jasmini 13 parts, nine sons not from female 12 parts, Fructus Tritici Levis 15 parts, Herba Polygoni japonici 16 parts, Semen Cajani root 14 parts, Folium seu Fructus Tarennae 16 parts, scrofula grass 14 parts, Olibanum 12 parts, tree head dish 13 parts, Phtheirospermum tenuisectum Bur.et Franch. 15 parts, Herba Astragali Sinici 13 parts, Radix Persicae 14 parts.The preparation method of the prosopalgic preparation unguentum of above-mentioned treatment is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 18 minutes, taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add the water of boiled crude drug quality 7 times, heating is boiled to boiling, continues 22 minutes, Guan Huohou, filters, and collects filtrate;
(5) pulverized by made to step (1) (2) (3) crude drug, mix with step (4) gained filtrate, heating is concentrated into the clear paste (75 DEG C) that relative density is 1.15, obtains unguentum.
Model case: xxx, women, 46 years old.Main suit: patient must have primary trigeminal neuralgia half a year, hurt like hell, and in acupuncture sample, each duration of seizure is shorter, with left side face muscle twitches time serious, once drug administration treatment, symptom is improved remarkable, then finds tcm methods treatment.
Take this example gained unguentum, each 6-10g, warm boiled water, one day twice, within 15 days, be a course for the treatment of, after patient takes a course for the treatment of, pain is obviously alleviated, and attack times reduces, after adhering to taking three courses for the treatment of, pain is not shown effect substantially, in drug withdrawal half a year, does not recur again.
embodiment 3cure prosopalgic preparation, be prepared from (every part of 10g) primarily of following bulk drugs: Caulis Spatholobi 9 parts, Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) 8 parts, suona horn spends 11 parts, Herba Passiflorae Caeruleae 9 parts, ti 8 parts, Flos jasmini 10 parts, nine sons not from female 9 parts, Fructus Tritici Levis 10 parts, Herba Polygoni japonici 12 parts, Semen Cajani root 10 parts, Folium seu Fructus Tarennae 11 parts, scrofula grass 9 parts, Olibanum 10 parts, tree head dish 11 parts, Phtheirospermum tenuisectum Bur.et Franch. 10 parts, Herba Astragali Sinici 8 parts, Radix Persicae 11 parts.The preparation method of the prosopalgic preparation decoction of above-mentioned treatment is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 18 minutes, taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add the water of boiled crude drug quality 7 times, heating is boiled to boiling, continues 22 minutes, Guan Huohou, filters, and collects filtrate;
(5) step (1) (2) (3) made crude drug was pulverized 90 mesh sieves, be added in step (4) gained filtrate, heated and boiled, and after filtration, collected filtrate, obtain decoction.
Model case: xxx, male, 52 years old.Main suit: when brushing teeth morning in the recent period, without paroxysmal pain facial on the right side of obvious inducement, lower jaw is as lightning sample pain, normally cannot dehisce, have a strong impact on the orthobiosis of patient, once took carbamazepine, have certain effect, but fail to improve completely, patient is very painful.
Recommend to take this example gained decoction, each 200-300ml through people, warmly to take, one day twice, within 15 days, be a course for the treatment of, after patient takes a course for the treatment of, pain degree alleviates, and number of times reduces, continue to take a course for the treatment of, patient is almost recovered, and drug withdrawal was followed up a case by regular visits to after 1 year, and the state of an illness does not recur again.
embodiment 4cure prosopalgic preparation, be prepared from (every part of 10g) primarily of following bulk drugs: Caulis Spatholobi 12 parts, Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) 10 parts, suona horn spends 13 parts, Herba Passiflorae Caeruleae 13 parts, ti 12 parts, Flos jasmini 12 parts, nine sons not from female 11 parts, Fructus Tritici Levis 14 parts, Herba Polygoni japonici 14 parts, Semen Cajani root 12 parts, Folium seu Fructus Tarennae 14 parts, scrofula grass 12 parts, Olibanum 11 parts, tree head dish 12 parts, Phtheirospermum tenuisectum Bur.et Franch. 13 parts, Herba Astragali Sinici 11 parts, Radix Persicae 12 parts.The preparation method of the prosopalgic preparation of above-mentioned treatment is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 18 minutes, taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add the water of boiled crude drug quality 7 times, heating is boiled to boiling, continues 22 minutes, Guan Huohou, filters, and collects filtrate;
(5) concentration step (4) gained filtrate, pulverized 150 mesh sieves after drying, obtained powder together with step (1) (2) (3) made crude drug.
Model case: xxx, male, 63 years old.Main suit: face ache on the left of paroxysmal repeatedly, increases the weight of three months; , there is left side buccal and bicker pain in medical history: during patient's laboratory rodent chow, in electric shock sample, duration of seizure is about about 1 minute, recurrent exerbation in a day, without other uncomfortable diseases, through hospital diagnosis, is diagnosed as trigeminal neuralgia repeatedly.
Take this example gained powder, each 4-6g, warm boiled water, one day twice, within 15 days, be a course for the treatment of, after patient takes a course for the treatment of, pain symptom alleviates, and continues to take a course for the treatment of, pain is not shown effect substantially, and patient's self-induction is fully recovered, and in drug withdrawal half a year, the state of an illness is not shown effect.
embodiment 5cure prosopalgic preparation, be prepared from (every part of 10g) primarily of following bulk drugs: Caulis Spatholobi 10.5 parts, Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) 9 parts, suona horn spends 12 parts, Herba Passiflorae Caeruleae 11 parts, ti 10 parts, Flos jasmini 11 parts, nine sons not from female 10 parts, Fructus Tritici Levis 12 parts, Herba Polygoni japonici 13 parts, Semen Cajani root 11 parts, Folium seu Fructus Tarennae 12.5 parts, scrofula grass 10.5 parts, Olibanum 10.5 parts, tree head dish 11.5 parts, Phtheirospermum tenuisectum Bur.et Franch. 11.5 parts, Herba Astragali Sinici 9.5 parts, Radix Persicae 11.5 parts.The preparation method of the prosopalgic preparation granules agent of above-mentioned treatment is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 18 minutes, taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add decocting in water to boiling (amount of water with boil crude drug mass ratio be 6:1), continue 22 minutes, Guan Huohou, filter, collect filtrate, concentrated filtrate is to thick paste;
(5) pulverized by made to step (1) (2) (3) crude drug, mix with step (4) gained thick paste, add adjuvant, make soft material, extruding is sieved, and makes wet granular, dries granulate, obtains granule.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Caulis Spatholobi: nature and flavor with return through: bitter, sweet, temperature.Return Liver and kidney warp.There is blood circulation promoting and enriching, menstruction regulating and pain relieving, effect of relaxing muscles and tendons and activating QI and blood in the collateral.For menoxenia, dysmenorrhea. amenorrhea, rheumatic arthralgia, paralysis and numbness, blood deficiency and yellow complexion.
Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae): base is former: be the fruit of rosaceous plant fire sour jujube.Nature and flavor: sweet; Acid; Puckery; Flat; Nontoxic.Gui Jing: liver; Spleen; Stomach warp.Function cures mainly: spleen invigorating removing food stagnancy; Convergence dysentery relieving; Pain relieving.Main mass in the abdomen; Food stagnation is stagnated; Distension and fullness in the abdomen; Have loose bowels; Dysentery; Metrorrhagia; Leukorrhagia; Traumatic injury.
Suona horn flower: base is former: be the band rhizome herb of Bignoniaceae Incarvillea AJuss plant Herba Melicae Scabrosae.The property of medicine: bitter, cool.Function cures mainly: invigorating spleen to remove dampness, promoting flow of QI and blood.Cure mainly dysentery, stomachache, costalgia, rheumatalgia, menoxenia, carbuncle, fracture.
Herba Passiflorae Caeruleae: base is former: be the herb of Passifloraceae plant Herba Passiflorae Caeruleae.Nature and flavor: bitter in the mouth; Warm in nature.Function cures mainly: except wind; Dehumidifying; Invigorate blood circulation; Pain relieving.Main headache due to common cold; Nasal obstruction watery nasal discharge; Rheumatic arthritis; Dysmenorrhea; Neuralgia; Lose eye; Dysentery; Fracture.
Ti: base is former: be leaf or the root of Agavaceae Cordyline plant ti.The property of medicine: sweet, light, be slightly cold.Function cures mainly: cooling blood for hemostasis, dissipating blood stasis analgesic therapy.Cure mainly hemoptysis, spit blood, epistaxis, hematuria, has blood in stool, metrorrhagia, stomachache, bones and muscles pain, treating swelling and pain by traumatic injury.
Flos jasmini: base is former: be the dry flower of Oleaceae plants Flos jasmini.Nature and flavor: micro-hardship; Property is put down.Gui Jing: Liver Channel.Function cures mainly: soothing liver-QI for relieving depression; Promoting the circulation of QI to relieve pain.Side of body rib gastral cavity abdomen caused by main stagnation of QI due to depression of the liver is had a pain; Dysentery is suffered from abdominal pain.
Nine sons are not from mother: base is former: be the rhizome of Dioscoreaceae plant Rhizoma Dioscoreae Hypoglaucae.Nature and flavor: bitter; Micro-pungent; Be slightly cold.Function cures mainly: expelling wind and removing dampness; Removing obstruction in the collateral to relieve pain; Heat-clearing and toxic substances removing.Main air pain of dampness syndrome; Contracture is numb; Peratodynia; Jaundice due to damp-heat; Nebulousurine; Drench pain; Leucorrhea; Traumatic pain; Eczema toxic swelling; Rubella; Eczema; Venom.
Fructus Tritici Levis: base is former: the fruit of the frivolous lack of filling power of drying of grass family Triticum plant Semen Tritici aestivi.Gather during fruit maturation, get the wheat grain of the frivolous and non-peeling of lack of filling power, decontamination, sieve dedust bits, with water rinse, dry.Nature and flavor: sweet are cool.Function cures mainly: only sweating due to debility, tranquilizing by nourishing the heart.For the empty hyperhidrosis of body, hysteria.
Herba Polygoni japonici: base is former: be the herb of polygonaceae plant Herba Polygoni japonici.Nature and flavor: pungent; Warm in nature.Function cures mainly: removing toxic substances; Pain relieving; Rash.Main skin infection swells and ache; Parasites is bitten; Diarrhoea; Dysentery; The cold pain of waist knee joint; Measles is sent out not smooth thoroughly.
Semen Cajani root: base is former: be the root of pulse family Semen Cajani platymiscium Semen Cajani.The property of medicine: bitter, cold.Function cures mainly: heat-clearing and toxic substances removing, dampness removing, hemostasis.Cure mainly laryngopharynx swelling and pain, ulcer sore pain, bleeding hemorrhoids, stranguria with blood, edema, dysuria.
Folium seu Fructus Tarennae: base is former: be the Ye Jigen of dicotyledon medicine Maguireothamnus speciosus Folium seu Fructus Tarennae.Nature and flavor: micro-hardship; Cool.Gui Jing: liver; Kidney channel.Function cures mainly: heat-clearing and toxic substances removing; Expelling wind and removing dampness.Main cold, fever; Cough; Acute tonsillitis; Headache; Rheumatic arthritis; Sciatica; Oedema due to nephritis; Wound; Furuncle abscess.
Scrofula grass: base is former: for Primulaceae Herba Lysimachiae Fortunei platymiscium prolongs the herb of leaf Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis).The property of medicine: bitter, pungent, flat.Function cures mainly: heat-clearing and toxic substances removing, blood circulation promoting and dispersing pathogen accumulation.Cure mainly scrofula, sore throat, furuncle swelling toxin, menoxenia, traumatic injury.
Olibanum: base is former: be the gum resin of olive subject plant Boswellia carterii Birdw.Nature and flavor with return through: pungent, bitter, temperature.GUIXIN, liver, spleen channel.To invigorate blood circulation effect of analgesic therapy, detumescence and promoting granulation.For obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation, addiction abdominal mass is suffered from abdominal pain, rheumatic arthralgia, the contracture of muscle arteries and veins, traumatic injury, carbuncle skin infection.
Tree head dish: base is former: be stem, the leaf of Capparidaceae plant tree head dish.Nature and flavor: bitter in the mouth; Cold in nature.Function cures mainly: heat-clearing and toxic substances removing; Stomach invigorating.Main acute filthy disease heating; Rotten skin ulcer; Venom; Stomachache; Rheumatic arthritis.
Phtheirospermum tenuisectum Bur.et Franch.: base is former: be the herb of Scrophulariaceae Phtheirospermum plant Phtheirospermum tenuisectum Bur.et Franch..The property of medicine: pungent, micro-hardship, flat.Function cures mainly: dissipating blood stasis detoxifies, tranquilizing by nourishing the heart.Cure mainly fracture to swell and ache, cough, sputum mixed with blood, laryngopharynx swelling and pain, myocardium palpitation with a distress feeling, Serpentis lyssodexis.
Herba Astragali Sinici: base is former: be the herb of leguminous plant Herba Astragali Melilotoidis (Herba Astragali Sinici).Nature and flavor: Gan Xin; Flat.Gui Jing: the heart; Liver; Lung meridian.Function cures mainly: heat-clearing and toxic substances removing, dispelling pathogenic wind for improving eyesight, cooling blood for hemostasis.Main throat pain, wind-phlegm is coughed, conjunctival congestion and swelling pain, furuncle, herpes zoster, scabies, hemorrhoid, bleeding from the gum, traumatic hemorrhage, menoxenia, leukorrhagia, thrombocytopenic purpura.
Radix Persicae: base is former: be root or the root bark of rosaceous plant Fructus Persicae or Prunus davidiana.Nature and flavor: bitter; Flat; Nontoxic.Gui Jing: Liver Channel.Function cures mainly: clearing away heat-damp and promoting diuresis, promoting blood circulation and stopping pain; Subduing inflammation.Main jaundice; Spit blood; Epistaxis; Amenorrhea; Carbuncle; Hemorrhoid; Rheumatic arthralgia; Traumatic injury impairment caused by overstrain pain; Lumbago; Eruptive disease is suffered from abdominal pain.
test example 1gained of the present invention cures the clinical practice of prosopalgic preparation (embodiment 5):
Choose crowd: in January, 2014 in December ,-2014, according to medical case history, have prosopalgic patient 255 example five hospitals' screenings, age 44-70 year, 54.7 ± 1.6 years old mean age, the course of disease 1 month-5 years, wherein male patient 130 example, female patient 125 example.Diagnostic criteria: the paroxysmal pain that (1) nervi trigeminus areal area occurs; (2) pain is paroxysmal, and to several minutes not etc., the intermission is completely normal for each outbreak last for several seconds; (3) pain be lightning sample, electric shock sample, electrical sensation acutely unbearably, when washing one's face, brush teeth, drink water, speak, even wind time can bring out; (4) there is trigger point phenomenon in the region (as upperlip, bicker, gingiva, tongue, the wing of nose etc.) of sensory ending integrated distribution; (5) at the disease initial stage, carbamazepine treatment effectively; (6) neurologic check does not have positive sign more.
Before test, patient is divided into two groups at random, experimental group 150 example and matched group 105 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 4-6g, one day twice, warm boiled water, within 15 days, is a course for the treatment of; Matched group takes other conventional medicines (Radix Schefflerae Arboricolae sheet, carbamazepine, large Rhizoma Chuanxiong sheet etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: pain disappears completely, follows up a case by regular visits in 6 months and does not recur; (2) effective: pain disappears completely, follow up a case by regular visits in six months and have recurrence, but outbreak the frequency comparatively before less more than 50%; (3) effective: pain obviously alleviates, the outbreak frequency is comparatively front reduces 25%-50%; (4) invalid: symptom is not improved.Total effective rate=cure rate+obvious effective rate+effective percentage.
Clinical effectiveness: after the taking medicine of three courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, the healing patient of experimental group is 98 examples, and effective patient is 32 examples, and effective patient is 16 examples, total effective rate is 97.3%, and the patient that matched group is cured is 48 examples, effective patient is 27 examples, and effective patient is 12 examples, total effective rate 82.8%, be starkly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.
The Chinese medicine used in the present invention, Caulis Spatholobi can menstruction regulating and pain relieving, Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) can spleen invigorating removing food stagnancy, suona horn flower can promoting flow of QI and blood, Herba Passiflorae Caeruleae, Olibanum, Radix Persicae can promoting blood circulation and stopping pain, ti can dissipating blood stasis analgesic therapy, and Flos jasmini can promoting the circulation of QI to relieve pain, and nine sons can removing obstruction in the collateral to relieve pain from mother, Fructus Tritici Levis, Phtheirospermum tenuisectum Bur.et Franch. can tranquilizing by nourishing the hearts, Herba Polygoni japonici can detoxify pain relieving, and Semen Cajani root, tree head dish can heat-clearing and toxic substances removing, and Folium seu Fructus Tarennae can expelling wind and removing dampness, the sub-grass of scrofula can blood circulation promoting and dispersing pathogen accumulation, Herba Astragali Sinici can dispelling pathogenic wind for improving eyesight, and multiple medical material synergism, plays effect of promoting flow of QI and blood, dissipating blood stasis analgesic therapy altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. cure prosopalgic preparation, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Caulis Spatholobi 8-13; Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) 6-12; Suona horn flower 10-14; Herba Passiflorae Caeruleae 7-15; Ti 6-14; Flos jasmini 9-13; Nine sons are not from female 8-12; Fructus Tritici Levis 9-15; Herba Polygoni japonici 10-16; Semen Cajani root 8-14; Folium seu Fructus Tarennae 9-16; The careless 7-14 of scrofula; Olibanum 9-12; Tree head dish 10-13; Phtheirospermum tenuisectum Bur.et Franch. 8-15; Herba Astragali Sinici 6-13; Radix Persicae 9-14.
2. the prosopalgic preparation for the treatment of as claimed in claim 1, is characterized in that, Caulis Spatholobi 9-12; Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) 8-10; Suona horn flower 11-13; Herba Passiflorae Caeruleae 9-13; Ti 8-12; Flos jasmini 10-12; Nine sons are not from female 9-11; Fructus Tritici Levis 10-14; Herba Polygoni japonici 12-14; Semen Cajani root 10-12; Folium seu Fructus Tarennae 11-14; The careless 9-12 of scrofula; Olibanum 10-11; Tree head dish 11-12; Phtheirospermum tenuisectum Bur.et Franch. 10-13; Herba Astragali Sinici 8-11; Radix Persicae 11-12(is preferably: Caulis Spatholobi 10.5; Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) 9; Suona horn spends 12; Herba Passiflorae Caeruleae 11; Ti 10; Flos jasmini 11; Nine sons are not from female 10; Fructus Tritici Levis 12; Herba Polygoni japonici 13; Semen Cajani root 11; Folium seu Fructus Tarennae 12.5; Scrofula grass 10.5; Olibanum 10.5; Tree head dish 11.5; Phtheirospermum tenuisectum Bur.et Franch. 11.5; Herba Astragali Sinici 9.5; Radix Persicae 11.5).
3. the prosopalgic preparation for the treatment of as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable granule, its preparation method is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 12-24 minute (preferred: Steam by water bath 16-20 minute; Be more preferably: Steam by water bath 18 minutes), taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add decocting in water to boiling, continue 16-28 minute (preferably: continue 20-24 minute; Be more preferably: continue 22 minutes), Guan Huohou, filters, and collect filtrate, concentrated filtrate is to thick paste;
(5) pulverized by made to step (1) (2) (3) crude drug, mix with step (4) gained thick paste, add adjuvant, make soft material, extruding is sieved, and makes wet granular, dries granulate, obtains granule.
4. the as claimed in claim 3 preparation method curing prosopalgic preparation granules agent, is characterized in that, step (4) amount of water with boil crude drug mass ratio be 6:1.
5. the prosopalgic preparation for the treatment of as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 12-24 minute (preferred: Steam by water bath 16-20 minute; Be more preferably: Steam by water bath 18 minutes), taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), heating is boiled to boiling, continues 16-28 minute (preferably: continue 20-24 minute; Be more preferably: continue 22 minutes), Guan Huohou, filters, and collects filtrate;
(5) pulverized by made to step (1) (2) (3) crude drug, mix with step (4) gained filtrate, heating is concentrated into clear paste, obtains unguentum.
6. the preparation method curing prosopalgic preparation unguentum as claimed in claim 5, is characterized in that, it is (preferred: heating is concentrated into the clear paste that relative density is 1.12-1.18 that step (5) heating is concentrated into the clear paste that relative density is 1.10-1.20; Be more preferably: heating is concentrated into the clear paste that relative density is 1.15).
7. the prosopalgic preparation for the treatment of as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 12-24 minute (preferred: Steam by water bath 16-20 minute; Be more preferably: Steam by water bath 18 minutes), taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), heating is boiled to boiling, continues 16-28 minute (preferably: continue 20-24 minute; Be more preferably: continue 22 minutes), Guan Huohou, filters, and collects filtrate;
(5) step (1) (2) (3) made crude drug is pulverized and sieved, be added in step (4) gained filtrate, heated and boiled, after filtration, collect filtrate, obtain decoction.
8. the preparation method curing prosopalgic preparation decoction as claimed in claim 7, is characterized in that, it is (preferred: to pulverize 80-100 mesh sieve that step (5) pulverized 60-120 mesh sieve; Be more preferably: pulverized 90 mesh sieves).
9. the prosopalgic preparation for the treatment of as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Fructus Pyracanthae (Fructus Pyracanthae Fortuneanae) and Fructus Tritici Levis roguing to clean, add hydromel and mix thoroughly, be placed in steamer, Steam by water bath 12-24 minute (preferred: Steam by water bath 16-20 minute; Be more preferably: Steam by water bath 18 minutes), taking-up is smashed to pieces, then puts into frying pan, drenches and stir-fries to drying into yellow wine, takes out;
(2) get Olibanum to clean and smash, be placed in frying pan, the alcoholic solution adding concentration 70% did not have crude drug 1cm, and slow fire is heated to ethanol combustion, and constantly stir-fried to time fuel-displaced, then added wheat bran, and continuing to fry be that yellow is heaved to Olibanum, took out to dry in the air cool, sieved and removed wheat bran;
(3) cleaned by Semen oryzae sativae, be placed in frying pan, drench into rice vinegar and stir-fry to emitting steam, add the clean Herba Passiflorae Caeruleae of wash quickly, Flos jasmini, Herba Polygoni japonici, scrofula grass, tree head dish, Phtheirospermum tenuisectum Bur.et Franch. Flos Carthami dish, stir to surface in yellow, take out, sieve removes rice;
(4) Caulis Spatholobi, suona horn flower, ti, nine sons are not cleaned from mother, Semen Cajani root, Folium seu Fructus Tarennae and Radix Persicae roguing, be placed in non iron container, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), heating is boiled to boiling, continues 16-28 minute (preferably: continue 20-24 minute; Be more preferably: continue 22 minutes), Guan Huohou, filters, and collects filtrate;
(5) concentration step (4) gained filtrate, pulverizes and sieves after drying, obtains powder together with step (1) (2) (3) made crude drug.
10. the preparation method curing prosopalgic preparation powder as claimed in claim 9, is characterized in that, it is (preferred: to pulverize 140-160 mesh sieve that step (5) pulverized 120-180 mesh sieve; Be more preferably: pulverized 150 mesh sieves).
CN201510558651.7A 2015-09-06 2015-09-06 Preparation for treating prosopalgia and preparation method Pending CN105079552A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103599409A (en) * 2013-11-16 2014-02-26 崔新明 Traditional Chinese medicinal composition for treating prosopalgia
CN104740208A (en) * 2015-04-08 2015-07-01 宋修响 Traditional Chinese medicine preparation for treatment of prosopalgia and preparation method thereof
CN104784378A (en) * 2015-04-26 2015-07-22 李志刚 Medicament for curing primary trigeminal neuralgia

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103599409A (en) * 2013-11-16 2014-02-26 崔新明 Traditional Chinese medicinal composition for treating prosopalgia
CN104740208A (en) * 2015-04-08 2015-07-01 宋修响 Traditional Chinese medicine preparation for treatment of prosopalgia and preparation method thereof
CN104784378A (en) * 2015-04-26 2015-07-22 李志刚 Medicament for curing primary trigeminal neuralgia

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